Mus musculus

31 known processes

Aqp4

aquaporin 4

(Aliases: WCH4)

Aqp4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.328
Mouse
inorganic ion transmembrane transportGO:00986602340.238
Mouse
organic anion transportGO:00157111370.230
synaptic transmissionGO:00072683290.203
anion transmembrane transportGO:0098656710.192
l amino acid transportGO:0015807320.181
transmembrane transportGO:00550854120.180
amino acid transmembrane transportGO:0003333370.165
organic acid transportGO:00158491010.156
anion transportGO:00068201770.156
nitrogen compound transportGO:00717052710.150
Mouse
cation transportGO:00068123990.147
Mouse
cation transmembrane transportGO:00986552660.146
Mouse
inorganic cation transmembrane transportGO:00986622070.144
Mouse
cation homeostasisGO:00550802120.127
sodium ion transportGO:0006814730.118
cellular amino acid metabolic processGO:00065201030.117
sodium ion transmembrane transportGO:0035725490.098
multicellular organismal signalingGO:0035637910.090
action potentialGO:0001508780.086
organic acid biosynthetic processGO:0016053860.086
carboxylic acid transportGO:00469421000.078
neuronal action potentialGO:0019228540.073
monocarboxylic acid metabolic processGO:00327871910.072
amino acid transportGO:0006865610.071
positive regulation of cellular amine metabolic processGO:003324050.067
transmission of nerve impulseGO:0019226760.067
skin developmentGO:00435882200.066
nucleoside metabolic processGO:00091162460.066
positive regulation of cellular amino acid metabolic processGO:004576430.064
cellular amine metabolic processGO:0044106440.064
nucleotide metabolic processGO:00091173320.064
cellular lipid metabolic processGO:00442553230.060
neuron neuron synaptic transmissionGO:0007270690.060
chloride transportGO:0006821320.059
locomotory behaviorGO:00076261950.057
amide transportGO:00428861380.057
Mouse
ribonucleoside catabolic processGO:00424542060.056
response to organonitrogen compoundGO:00102432460.056
cellular component assembly involved in morphogenesisGO:00109271390.055
oxidation reduction processGO:00551143420.054
regulation of cellular ketone metabolic processGO:0010565660.053
adult behaviorGO:00305341350.053
regulation of membrane potentialGO:00423911920.053
regulation of transmembrane transportGO:00347621280.052
metal ion homeostasisGO:00550651890.052
forebrain developmentGO:00309003020.052
Mouse
l alpha amino acid transmembrane transportGO:1902475230.052
carboxylic acid biosynthetic processGO:0046394860.051
protein targetingGO:00066051430.051
amine metabolic processGO:0009308450.050
organonitrogen compound catabolic processGO:19015652640.048
regulation of secretionGO:00510462740.048
purine ribonucleotide metabolic processGO:00091502900.047
regulation of cellular catabolic processGO:00313292420.047
regulation of blood circulationGO:1903522930.047
lipid biosynthetic processGO:00086101790.046
response to radiationGO:00093141650.046
protein localization to organelleGO:00333651850.045
regulation of hormone levelsGO:00108172110.045
Mouse
cellular homeostasisGO:00197252400.045
purine ribonucleoside metabolic processGO:00461282410.044
regulation of chloride transportGO:200122520.044
cytoplasmic transportGO:00164822340.043
cellular chemical homeostasisGO:00550822150.043
regulation of neurotransmitter levelsGO:0001505870.043
organic hydroxy compound metabolic processGO:19016152030.043
regulation of cellular amino acid metabolic processGO:000652150.043
cellular ion homeostasisGO:00068731650.042
myelinationGO:0042552740.042
regulation of protein localizationGO:00328802310.042
cellular ketone metabolic processGO:0042180840.042
regulation of cellular amine metabolic processGO:0033238200.041
purine nucleoside catabolic processGO:00061522050.041
ribonucleoside triphosphate metabolic processGO:00091992200.041
purine nucleotide metabolic processGO:00061633020.041
cellular metal ion homeostasisGO:00068751510.041
inorganic anion transmembrane transportGO:0098661290.041
sensory perceptionGO:00076002450.040
purine containing compound metabolic processGO:00725213110.040
chloride transmembrane transportGO:1902476240.040
regulation of ion transportGO:00432692150.040
hormone metabolic processGO:0042445860.039
nucleoside phosphate metabolic processGO:00067533380.039
regulation of nucleotide metabolic processGO:00061401690.038
purine nucleoside triphosphate metabolic processGO:00091442260.038
regulation of body fluid levelsGO:00508781620.037
organonitrogen compound biosynthetic processGO:19015661920.037
inorganic anion transportGO:0015698430.037
blood circulationGO:00080151950.037
ribonucleoside metabolic processGO:00091192450.036
cellular calcium ion homeostasisGO:00068741190.036
ensheathment of neuronsGO:0007272760.036
divalent inorganic cation transportGO:00725111780.036
response to light stimulusGO:00094161350.036
monovalent inorganic cation homeostasisGO:0055067330.036
eye photoreceptor cell differentiationGO:0001754410.035
apoptotic signaling pathwayGO:00971903060.035
membrane organizationGO:00610242450.034
angiogenesisGO:00015252010.034
purine nucleoside triphosphate catabolic processGO:00091462030.033
regulation of protein transportGO:00512231630.033
epidermis developmentGO:00085441870.033
purine nucleotide catabolic processGO:00061952110.032
response to histamineGO:003477610.032
protein localization to nucleusGO:00345041210.032
cellular response to lipidGO:00713961450.032
regulation of response to drugGO:200102320.031
nucleocytoplasmic transportGO:00069131390.031
nucleoside triphosphate metabolic processGO:00091412300.031
positive regulation of cellular catabolic processGO:00313311480.031
muscle cell differentiationGO:00426922610.031
organophosphate catabolic processGO:00464342320.030
ribonucleotide metabolic processGO:00092592910.030
negative regulation of cell proliferationGO:00082852960.030
monocarboxylic acid biosynthetic processGO:0072330610.030
regulation of apoptotic signaling pathwayGO:20012331970.030
glycosyl compound metabolic processGO:19016572460.030
digestive tract developmentGO:00485651900.030
regulation of ion transmembrane transportGO:00347651190.030
regulation of establishment of protein localizationGO:00702011810.030
alpha amino acid metabolic processGO:1901605590.030
single organism nuclear importGO:1902593950.029
nucleotide catabolic processGO:00091662170.029
g protein coupled receptor signaling pathwayGO:00071862430.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
nucleobase containing small molecule metabolic processGO:00550863520.029
ras protein signal transductionGO:0007265770.029
cell type specific apoptotic processGO:00972852680.029
regulation of purine nucleotide catabolic processGO:00331211220.029
regulation of system processGO:00440572000.028
calcium ion homeostasisGO:00550741270.028
regulation of feeding behaviorGO:006025930.028
response to lipopolysaccharideGO:00324961280.028
axon ensheathmentGO:0008366760.028
peptide transportGO:00158331330.027
Mouse
peptide hormone secretionGO:00300721090.027
Mouse
ribose phosphate metabolic processGO:00196932910.027
intracellular protein transportGO:00068862040.027
purine ribonucleoside triphosphate metabolic processGO:00092052200.027
organic hydroxy compound transportGO:0015850930.027
ribonucleoside triphosphate catabolic processGO:00092031990.026
ossificationGO:00015032160.026
cellular nitrogen compound catabolic processGO:00442702800.026
sensory perception of mechanical stimulusGO:00509541070.026
regulation of metal ion transportGO:00109591060.025
small molecule biosynthetic processGO:00442831320.025
regulation of mapk cascadeGO:00434082480.025
hindbrain developmentGO:00309021280.025
purine nucleoside metabolic processGO:00422782410.025
regulation of organelle organizationGO:00330432890.025
response to organic cyclic compoundGO:00140701980.025
organic cyclic compound catabolic processGO:19013612950.025
muscle tissue developmentGO:00605373080.025
glycosyl compound catabolic processGO:19016582060.025
plasma membrane organizationGO:0007009900.025
carbohydrate metabolic processGO:00059752300.025
aromatic compound catabolic processGO:00194392860.025
skeletal system developmentGO:00015013560.025
regulation of phGO:0006885260.024
cell adhesionGO:00071553290.024
potassium ion homeostasisGO:005507540.024
organophosphate biosynthetic processGO:00904071220.024
cellular response to organonitrogen compoundGO:00714171450.024
stem cell differentiationGO:00488632680.024
establishment of protein localization to organelleGO:00725941180.024
muscle system processGO:00030121410.024
regulation of peptide transportGO:0090087910.024
divalent inorganic cation homeostasisGO:00725071380.023
sensory organ morphogenesisGO:00905962420.023
Mouse
actin filament based movementGO:0030048230.023
nucleoside phosphate catabolic processGO:19012922220.023
protein localization to membraneGO:00726571080.023
regulation of heart contractionGO:0008016770.023
ear developmentGO:00435832000.023
regulation of sodium ion transportGO:0002028290.022
synaptic transmission glycinergicGO:006001220.022
mapk cascadeGO:00001652810.022
glial cell differentiationGO:00100011310.022
inner ear receptor cell developmentGO:0060119390.022
circulatory system processGO:00030131970.022
nucleoside triphosphate catabolic processGO:00091432050.022
nucleoside catabolic processGO:00091642060.022
positive regulation of necrotic cell deathGO:001094010.022
negative regulation of phosphate metabolic processGO:00459361840.022
muscle contractionGO:00069361010.022
negative regulation of phosphorus metabolic processGO:00105631840.022
heart processGO:0003015940.022
heterocycle catabolic processGO:00467002800.022
nuclear transportGO:00511691390.021
striated muscle tissue developmentGO:00147062930.021
wound healingGO:00420601570.021
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.021
carbohydrate derivative biosynthetic processGO:19011371830.021
defecationGO:003042110.021
purine ribonucleoside catabolic processGO:00461302050.021
regulation of cell activationGO:00508652890.021
neurotransmitter transportGO:0006836760.021
carbohydrate derivative catabolic processGO:19011362310.021
neuron deathGO:00709971540.021
cellular amino acid biosynthetic processGO:0008652220.021
regulation of cell migrationGO:00303342190.021
Mouse
learning or memoryGO:00076111480.021
regulation of gtp catabolic processGO:00331241130.021
retina development in camera type eyeGO:00600411190.021
monoamine transportGO:0015844330.020
anatomical structure homeostasisGO:00602491450.020
purine containing compound catabolic processGO:00725232130.020
regulation of secretion by cellGO:19035302490.020
myeloid cell differentiationGO:00300992330.020
positive regulation of cellular ph reductionGO:003284920.020
regulation of ion transmembrane transporter activityGO:0032412540.020
visual perceptionGO:0007601520.020
Mouse
heart contractionGO:0060047930.020
epithelial tube morphogenesisGO:00605623030.020
immune effector processGO:00022523210.020
dephosphorylationGO:00163111290.020
gland developmentGO:00487323300.019
response to nutrient levelsGO:00316671090.019
protein importGO:00170381010.019
small gtpase mediated signal transductionGO:0007264970.019
fat cell differentiationGO:00454441600.019
ribonucleotide catabolic processGO:00092612080.019
positive regulation of protein modification processGO:00314012990.018
regulation of cytokine productionGO:00018172660.018
cell junction organizationGO:0034330770.018
regulation of purine nucleotide metabolic processGO:19005421690.018
purine ribonucleotide catabolic processGO:00091542080.018
male gamete generationGO:00482322850.018
tissue homeostasisGO:00018941150.018
positive regulation of cell motilityGO:20001471160.018
Mouse
phenol containing compound metabolic processGO:0018958600.018
regulation of cell cycleGO:00517262810.018
peptide secretionGO:00027901140.018
Mouse
multicellular organismal response to stressGO:0033555620.018
cellular response to ammonium ionGO:007124220.017
regulation of cellular response to stressGO:00801351590.017
engulfment of apoptotic cellGO:004365230.017
regulation of neuron apoptotic processGO:00435231220.017
regulation of circadian sleep wake cycleGO:004274930.017
sensory perception of light stimulusGO:0050953540.017
Mouse
positive regulation of protein phosphorylationGO:00019342420.017
synaptic transmission gabaergicGO:0051932190.017
regulation of anatomical structure sizeGO:00900661780.017
membrane lipid metabolic processGO:0006643530.017
cellular carbohydrate metabolic processGO:00442621190.017
response to extracellular stimulusGO:00099911270.017
Mouse
protein import into nucleusGO:0006606950.017
nucleoside monophosphate metabolic processGO:0009123850.017
regulation of cytoskeleton organizationGO:00514931220.017
posttranscriptional regulation of gene expressionGO:00106081550.017
c4 dicarboxylate transportGO:001574030.017
actin filament organizationGO:00070151130.016
regulation of cytoplasmic transportGO:19036491120.016
divalent metal ion transportGO:00708381720.016
regulation of actin filament based processGO:0032970990.016
sensory perception of soundGO:0007605970.016
connective tissue developmentGO:00614481790.016
organelle localizationGO:00516401790.016
negative regulation of intracellular signal transductionGO:19025321670.016
regulation of muscle system processGO:0090257800.016
sa node cell action potentialGO:008601540.016
peptidyl amino acid modificationGO:00181933360.016
epithelial cell developmentGO:00020641590.016
adult locomotory behaviorGO:0008344910.016
cellular response to growth factor stimulusGO:00713631970.016
fatty acid metabolic processGO:00066311210.016
positive regulation of cell migrationGO:00303351090.016
Mouse
regulation of circadian sleep wake cycle sleepGO:004518730.016
regulation of nucleoside metabolic processGO:00091181300.016
gtp metabolic processGO:00460391440.016
t cell activationGO:00421102890.016
multicellular organismal homeostasisGO:00488711640.016
glycerophospholipid metabolic processGO:0006650710.015
lipid localizationGO:00108761260.015
cellular protein complex assemblyGO:00436231160.015
regulation of t cell activationGO:00508631700.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
cognitionGO:00508901490.015
positive regulation of programmed cell deathGO:00430682180.015
cellular response to histamineGO:007142010.015
positive regulation of apoptotic processGO:00430652170.015
pallium developmentGO:00215431200.015
guanosine containing compound catabolic processGO:19010691440.015
protein polymerizationGO:0051258570.015
response to acid chemicalGO:00011011110.015
Mouse
lipid modificationGO:0030258650.015
skeletal muscle organ developmentGO:00605381630.015
guanosine containing compound metabolic processGO:19010681440.015
regulation of nucleotide catabolic processGO:00308111220.015
associative learningGO:0008306610.015
establishment of organelle localizationGO:00516561220.015
regulation of hormone secretionGO:0046883880.015
regulation of cellular component biogenesisGO:00440871810.015
amino acid import into cellGO:190283740.015
actin cytoskeleton organizationGO:00300362200.015
response to growth factorGO:00708481980.015
norepinephrine transportGO:001587420.015
stem cell developmentGO:00488642190.015
camera type eye developmentGO:00430102660.015
Mouse
dicarboxylic acid transportGO:0006835290.014
microtubule based processGO:00070172360.014
fear responseGO:0042596330.014
rhythmic processGO:00485111740.014
synaptic transmission glutamatergicGO:0035249360.014
multicellular organism growthGO:00352641610.014
glutamine family amino acid biosynthetic processGO:000908420.014
endocytosisGO:00068971680.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
cartilage developmentGO:00512161400.014
energy derivation by oxidation of organic compoundsGO:0015980770.014
regulation of hydrolase activityGO:00513362460.014
nuclear importGO:0051170950.014
glycerolipid metabolic processGO:00464861220.014
defense response to other organismGO:00985421970.014
substantia nigra developmentGO:002176220.014
generation of precursor metabolites and energyGO:00060911030.014
positive regulation of protein kinase activityGO:00458601440.014
maintenance of locationGO:0051235890.014
cerebellum developmentGO:0021549770.014
glycoprotein metabolic processGO:00091001160.014
regulation of kinase activityGO:00435492490.014
actin filament polymerizationGO:0030041440.014
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.014
negative regulation of molecular functionGO:00440922580.014
glutamate biosynthetic processGO:000653720.014
behavioral response to nutrientGO:005178010.014
regulation of epithelial cell proliferationGO:00506781410.014
developmental maturationGO:00217001930.013
sa node cell to atrial cardiac muscle cell signallingGO:008601840.013
cytokine mediated signaling pathwayGO:00192211150.013
reactive oxygen species metabolic processGO:0072593840.013
defense response to virusGO:0051607680.013
positive regulation of ion transportGO:0043270650.013
cellular response to organic cyclic compoundGO:0071407870.013
blood vessel morphogenesisGO:00485142850.013
cardiac muscle cell contractionGO:008600370.013
actin mediated cell contractionGO:0070252150.013
response to inorganic substanceGO:0010035960.013
Mouse
carbohydrate transportGO:0008643620.013
response to molecule of bacterial originGO:00022371430.013
regulation of cell motilityGO:20001452360.013
Mouse
positive regulation of behaviorGO:0048520400.013
purine nucleotide biosynthetic processGO:0006164650.013
asymmetric stem cell divisionGO:009872230.013
regulation of ossificationGO:00302781120.013
positive regulation of white fat cell proliferationGO:007035210.013
regulation of intracellular transportGO:00323861590.013
endomembrane system organizationGO:00102561470.013
Mouse
metencephalon developmentGO:0022037890.013
membrane lipid biosynthetic processGO:0046467320.013
positive regulation of cell deathGO:00109422240.013
positive regulation of nucleotide metabolic processGO:00459811140.013
adult walking behaviorGO:0007628410.013
regulation of cell adhesionGO:00301551540.013
regulation of voltage gated calcium channel activityGO:190138540.013
striated muscle cell developmentGO:00550021250.013
neuromuscular processGO:0050905990.013
negative regulation of immune system processGO:00026832090.013
regulation of intracellular protein transportGO:0033157820.013
d amino acid transportGO:004294010.013
second messenger mediated signalingGO:0019932730.013
regulation of ras gtpase activityGO:0032318880.012
innate immune responseGO:00450871570.012
monocarboxylic acid transportGO:0015718440.012
cellular response to oxidative stressGO:0034599760.012
negative regulation of phosphorylationGO:00423261660.012
regulation of protein kinase activityGO:00458592320.012
regulation of blood pressureGO:0008217930.012
gtp catabolic processGO:00061841430.012
rho protein signal transductionGO:0007266320.012
embryonic organ morphogenesisGO:00485622760.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
lymphocyte differentiationGO:00300982420.012
sphingolipid metabolic processGO:0006665450.012
lipid transportGO:0006869980.012
regulation of neuron deathGO:19012141340.012
regulation of g protein activated inward rectifier potassium channel activityGO:190012810.012
exocytosisGO:00068871210.012
glucose transportGO:0015758560.012
learningGO:0007612980.012
mitotic cell cycleGO:00002781950.012
multi multicellular organism processGO:00447061090.012
regulation of synaptic plasticityGO:0048167870.012
protein oligomerizationGO:0051259670.012
calcium ion transmembrane transportGO:0070588850.012
positive regulation of mapk cascadeGO:00434101700.012
positive regulation of growthGO:00459271040.012
regulation of protein localization to nucleusGO:1900180600.012
nucleotide biosynthetic processGO:0009165780.011
relaxation of muscleGO:0090075180.011
ear morphogenesisGO:00424711180.011
positive regulation of cell developmentGO:00107202370.011
response to oxygen levelsGO:0070482620.011
cell divisionGO:00513011200.011
neurotransmitter uptakeGO:0001504140.011
positive regulation of nervous system developmentGO:00519622210.011
atp metabolic processGO:0046034750.011
av node cell to bundle of his cell communicationGO:008606720.011
gliogenesisGO:00420631410.011
l glutamate transportGO:0015813160.011
cellular modified amino acid metabolic processGO:0006575630.011
photoreceptor cell differentiationGO:0046530520.011
leukocyte differentiationGO:00025213420.011
mitotic cytokinesisGO:000028140.011
cell growthGO:00160491300.011
mitochondrion organizationGO:00070051340.011
cellular response to cytokine stimulusGO:00713451890.011
cellular response to hormone stimulusGO:00328701500.011
l glutamate uptake involved in synaptic transmissionGO:005193530.011
regulation of ras protein signal transductionGO:00465781140.011
morphogenesis of embryonic epitheliumGO:00163311590.011
regulation of cellular phGO:0030641120.011
protein localization to plasma membraneGO:0072659570.011
regulation of inward rectifier potassium channel activityGO:190197910.011
regulation of transferase activityGO:00513382630.011
neural precursor cell proliferationGO:00613511210.011
midgut developmentGO:000749440.011
ventricular cardiac muscle cell action potentialGO:008600540.011
bone developmentGO:00603481200.011
norepinephrine secretionGO:004824320.011
monosaccharide transportGO:0015749580.011
single organism cell adhesionGO:00986021560.011
rac protein signal transductionGO:0016601130.011
regulation of lymphocyte activationGO:00512492400.011
negative regulation of cellular amine metabolic processGO:003323910.011
regulation of protein bindingGO:0043393600.011
reflexGO:0060004220.011
regulation of stem cell proliferationGO:0072091780.011
response to sterolGO:003631440.010
respiratory tube developmentGO:00303231670.010
neuron migrationGO:00017641220.010
pigmentationGO:0043473710.010
response to drugGO:0042493750.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
inner ear receptor cell differentiationGO:0060113610.010
establishment of vesicle localizationGO:0051650810.010
acidic amino acid transportGO:0015800160.010
sequestering of calcium ionGO:0051208180.010
renal sodium excretionGO:003581230.010
respiratory system developmentGO:00605411900.010
regulation of resting membrane potentialGO:006007530.010
regulation of osteoblast differentiationGO:0045667670.010
placenta developmentGO:00018901400.010
telencephalon developmentGO:00215371860.010
Mouse
cellular response to cadmium ionGO:007127630.010
positive regulation of epithelial cell proliferationGO:0050679680.010
cerebral cortex developmentGO:0021987860.010
regulation of synaptic transmission gabaergicGO:0032228170.010
polysaccharide metabolic processGO:0005976390.010
mechanoreceptor differentiationGO:0042490670.010
heart morphogenesisGO:00030071780.010
regulation of homeostatic processGO:00328441820.010
regulation of protein import into nucleusGO:0042306520.010
homeostasis of number of cellsGO:00488722100.010
hydrogen ion transmembrane transportGO:1902600250.010
striated muscle contractionGO:0006941450.010
response to temperature stimulusGO:0009266550.010

Aqp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
nervous system diseaseDOID:86300.061
central nervous system diseaseDOID:33100.027
sensory system diseaseDOID:005015500.018
musculoskeletal system diseaseDOID:1700.018
neuropathyDOID:87000.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011
brain diseaseDOID:93600.011
organ system cancerDOID:005068600.011
neuromuscular diseaseDOID:44000.010