Mus musculus

22 known processes

Manf

mesencephalic astrocyte-derived neurotrophic factor

(Aliases: AA673178,Armet,D18Mgi17,AA408789,AA407711,3230402M22Rik,D17914)

Manf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to topologically incorrect proteinGO:0035966250.994
endoplasmic reticulum unfolded protein responseGO:0030968190.817
proteolysis involved in cellular protein catabolic processGO:00516031470.801
er nucleus signaling pathwayGO:0006984270.788
response to unfolded proteinGO:0006986210.784
cellular response to topologically incorrect proteinGO:0035967250.674
glycoprotein biosynthetic processGO:0009101890.571
cellular macromolecule catabolic processGO:00442652060.566
cellular response to antibioticGO:007123640.538
cellular response to interleukin 4GO:0071353210.536
ubiquitin dependent protein catabolic processGO:00065111290.409
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.382
carbohydrate metabolic processGO:00059752300.377
cellular response to toxic substanceGO:009723770.238
modification dependent macromolecule catabolic processGO:00436321330.224
proteasomal protein catabolic processGO:0010498980.206
glycoprotein metabolic processGO:00091001160.205
macromolecule catabolic processGO:00090572810.199
transmembrane transportGO:00550854120.193
protein targeting to membraneGO:0006612200.166
mrna metabolic processGO:0016071840.162
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.153
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.153
response to organonitrogen compoundGO:00102432460.144
response to antibioticGO:0046677110.137
modification dependent protein catabolic processGO:00199411330.131
protein catabolic processGO:00301632210.125
protein targeting to erGO:004504720.122
positive regulation of growth hormone secretionGO:006012430.105
substantia nigra developmentGO:002176220.099
macromolecule glycosylationGO:0043413550.093
positive regulation of protein ubiquitinationGO:0031398270.093
muscle cell differentiationGO:00426922610.091
protein n linked glycosylation via asparagineGO:001827910.088
digestive system developmentGO:00551232000.081
negative regulation of cellular response to growth factor stimulusGO:0090288460.081
intracellular protein transportGO:00068862040.080
cellular response to cytokine stimulusGO:00713451890.073
cellular response to biotic stimulusGO:0071216920.066
peptide transportGO:00158331330.065
positive regulation of interleukin 6 secretionGO:200077810.058
membrane lipid biosynthetic processGO:0046467320.057
protein localization to organelleGO:00333651850.056
cellular response to transforming growth factor beta stimulusGO:0071560880.056
toxin transportGO:1901998380.055
fertilizationGO:00095661270.054
localization within membraneGO:005166840.053
regulation of establishment of protein localizationGO:00702011810.053
protein n linked glycosylationGO:0006487120.052
regulation of dephosphorylationGO:0035303180.051
peptidyl asparagine modificationGO:001819610.051
maintenance of protein localization in organelleGO:007259520.051
interleukin 6 secretionGO:007260430.047
cotranslational protein targeting to membraneGO:000661320.047
chaperone mediated protein foldingGO:0061077100.047
nitrogen compound transportGO:00717052710.047
establishment of protein localization to membraneGO:0090150540.046
leukocyte differentiationGO:00025213420.046
cellular amine metabolic processGO:0044106440.045
regulation of cellular catabolic processGO:00313292420.043
aromatic compound catabolic processGO:00194392860.043
regulation of secretionGO:00510462740.043
interleukin 6 productionGO:0032635580.043
positive regulation of protein modification processGO:00314012990.043
cellular nitrogen compound catabolic processGO:00442702800.043
positive regulation of secretion by cellGO:19035321140.043
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.042
lipid biosynthetic processGO:00086101790.042
response to organic cyclic compoundGO:00140701980.041
protein targetingGO:00066051430.041
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.040
sensory organ morphogenesisGO:00905962420.040
protein transmembrane transportGO:007180680.040
extracellular matrix organizationGO:00301981470.039
amine metabolic processGO:0009308450.039
skeletal system developmentGO:00015013560.039
protein modification by small protein conjugation or removalGO:00706472070.038
regulation of organ morphogenesisGO:20000271440.038
positive regulation of cell activationGO:00508671580.038
response to extracellular stimulusGO:00099911270.037
cellular protein catabolic processGO:00442571550.036
regulation of cell motilityGO:20001452360.036
positive regulation of transferase activityGO:00513471670.036
regulation of cell cycleGO:00517262810.036
peptidyl amino acid modificationGO:00181933360.035
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.035
negative regulation of phosphorus metabolic processGO:00105631840.035
positive regulation of kinase activityGO:00336741550.035
cation transmembrane transportGO:00986552660.034
establishment of protein localization to endoplasmic reticulumGO:007259920.034
protein ubiquitinationGO:00165671710.034
regulation of hydrolase activityGO:00513362460.033
protein lipidationGO:0006497280.032
inorganic ion transmembrane transportGO:00986602340.032
positive regulation of hydrolase activityGO:00513451480.032
copii coated vesicle buddingGO:009011420.032
glycosylationGO:0070085620.031
cellular response to lipopolysaccharideGO:0071222770.030
gland developmentGO:00487323300.030
photoreceptor cell differentiationGO:0046530520.029
muscle tissue developmentGO:00605373080.029
positive regulation of growthGO:00459271040.029
carbohydrate homeostasisGO:00335001280.028
positive regulation of cell migrationGO:00303351090.028
regulation of cellular response to stressGO:00801351590.028
response to starvationGO:0042594650.027
liver developmentGO:0001889660.027
serotonin transportGO:0006837110.027
purine nucleoside catabolic processGO:00061522050.026
regulation of purine nucleotide metabolic processGO:19005421690.026
regulation of t cell activationGO:00508631700.026
heterocycle catabolic processGO:00467002800.026
regulation of lymphocyte activationGO:00512492400.026
regulation of cytokine productionGO:00018172660.026
positive regulation of cellular catabolic processGO:00313311480.025
positive regulation of t cell activationGO:00508701010.025
regulation of transferase activityGO:00513382630.025
midbrain developmentGO:0030901350.025
cation transportGO:00068123990.025
epithelial cell proliferationGO:00506731740.025
regulation of organelle organizationGO:00330432890.025
positive regulation of programmed cell deathGO:00430682180.025
regulation of protein exit from endoplasmic reticulumGO:007086110.025
carbohydrate derivative biosynthetic processGO:19011371830.024
production of molecular mediator of immune responseGO:00024401030.024
b cell differentiationGO:0030183780.024
lymphocyte differentiationGO:00300982420.024
regulation of protein secretionGO:0050708820.024
regulation of phosphatase activityGO:0010921120.023
t cell activationGO:00421102890.023
regulation of purine nucleotide catabolic processGO:00331211220.023
cellular response to lipidGO:00713961450.023
regulation of nucleoside metabolic processGO:00091181300.023
protein modification by small protein conjugationGO:00324461870.022
lymphocyte activation involved in immune responseGO:0002285930.022
er associated ubiquitin dependent protein catabolic processGO:0030433100.022
dephosphorylationGO:00163111290.022
hepaticobiliary system developmentGO:0061008670.021
er overload responseGO:000698360.021
posttranscriptional regulation of gene expressionGO:00106081550.021
plasma cell differentiationGO:000231730.021
b cell activationGO:00421131610.021
response to growth factorGO:00708481980.021
response to purine containing compoundGO:0014074280.021
regulation of cell migrationGO:00303342190.021
response to testosteroneGO:003357430.021
glucose homeostasisGO:00425931280.021
regulation of leukocyte differentiationGO:19021051590.020
regulation of mrna processingGO:0050684410.020
negative regulation of phosphate metabolic processGO:00459361840.020
hindbrain developmentGO:00309021280.020
positive regulation of protein phosphorylationGO:00019342420.020
cellular chemical homeostasisGO:00550822150.020
ribonucleotide metabolic processGO:00092592910.020
positive regulation of apoptotic signaling pathwayGO:2001235950.019
regulation of lymphocyte differentiationGO:00456191070.019
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.019
response to oxygen levelsGO:0070482620.019
immune effector processGO:00022523210.019
cellular response to starvationGO:0009267570.019
mitotic cytokinesisGO:000028140.018
nuclear divisionGO:00002801580.018
photoreceptor cell developmentGO:0042461400.018
cerebellum developmentGO:0021549770.018
transforming growth factor beta receptor signaling pathwayGO:0007179710.018
regulation of translationGO:0006417710.018
t cell differentiationGO:00302171740.017
organism emergence from protective structureGO:007168440.017
eye photoreceptor cell differentiationGO:0001754410.017
regulation of neuron differentiationGO:00456642810.017
developmental maturationGO:00217001930.017
striated muscle cell developmentGO:00550021250.017
immunoglobulin productionGO:0002377730.017
positive regulation of organelle organizationGO:00106381280.017
cytoplasmic transportGO:00164822340.017
anatomical structure arrangementGO:0048532200.017
cellular response to nutrient levelsGO:0031669640.016
hatchingGO:003518840.016
regulation of cellular amine metabolic processGO:0033238200.016
response to nutrient levelsGO:00316671090.016
guanosine containing compound catabolic processGO:19010691440.016
nuclear importGO:0051170950.016
nucleoside triphosphate catabolic processGO:00091432050.016
renal system developmentGO:00720012250.016
leukocyte migrationGO:00509001240.016
cellular amino acid metabolic processGO:00065201030.016
protein import into nucleusGO:0006606950.016
neural nucleus developmentGO:0048857220.016
regulation of cell activationGO:00508652890.016
regulation of epithelial cell proliferationGO:00506781410.015
cellular response to external stimulusGO:0071496880.015
body morphogenesisGO:0010171450.015
protein localization to membraneGO:00726571080.015
regulation of protein modification by small protein conjugation or removalGO:1903320570.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
regulation of t cell differentiationGO:0045580830.015
proteasome assemblyGO:004324810.015
male sex differentiationGO:00466611090.014
cellular response to molecule of bacterial originGO:0071219830.014
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.014
establishment of protein localization to organelleGO:00725941180.014
protein refoldingGO:004202610.014
apoptotic signaling pathwayGO:00971903060.014
sphingolipid metabolic processGO:0006665450.014
response to interleukin 4GO:0070670230.014
oocyte anterior posterior axis specificationGO:000731420.014
positive regulation of secretionGO:00510471300.014
guanosine containing compound metabolic processGO:19010681440.014
cytokine productionGO:00018163190.014
amide transportGO:00428861380.014
multi multicellular organism processGO:00447061090.014
cellular ketone metabolic processGO:0042180840.014
nucleoside catabolic processGO:00091642060.014
response to endoplasmic reticulum stressGO:0034976530.013
maintenance of locationGO:0051235890.013
regulation of gtp catabolic processGO:00331241130.013
protein foldingGO:0006457280.013
cerebellar purkinje cell layer developmentGO:0021680260.013
pore complex assemblyGO:004693130.013
regulation of cellular ketone metabolic processGO:0010565660.013
hormone secretionGO:00468791280.013
regulation of sphingolipid biosynthetic processGO:009015310.013
organelle disassemblyGO:190300820.013
negative regulation of cellular protein metabolic processGO:00322692470.013
hindbrain morphogenesisGO:0021575460.013
single fertilizationGO:0007338820.013
maintenance of location in cellGO:0051651240.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
eye photoreceptor cell developmentGO:0042462310.013
regulation of kinase activityGO:00435492490.013
kidney developmentGO:00018222130.012
organonitrogen compound biosynthetic processGO:19015661920.012
blastocyst developmentGO:0001824800.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
nucleotide catabolic processGO:00091662170.012
nuclear transportGO:00511691390.012
regulation of phosphoprotein phosphatase activityGO:004366630.012
regulation of nucleotide catabolic processGO:00308111220.012
inorganic cation transmembrane transportGO:00986622070.012
forebrain developmentGO:00309003020.012
multicellular organismal agingGO:0010259240.012
positive regulation of nucleotide metabolic processGO:00459811140.012
protein exit from endoplasmic reticulumGO:003252710.012
rna splicing via transesterification reactionsGO:0000375430.012
neural tube formationGO:00018411080.012
purine containing compound catabolic processGO:00725232130.012
cellular response to hexose stimulusGO:0071331470.012
organic cyclic compound catabolic processGO:19013612950.012
cell activation involved in immune responseGO:00022631260.012
regulation of mapk cascadeGO:00434082480.011
lipid localizationGO:00108761260.011
lipoprotein biosynthetic processGO:0042158330.011
positive regulation of cell motilityGO:20001471160.011
cellular lipid metabolic processGO:00442553230.011
positive regulation of protein transportGO:0051222930.011
protein glycosylationGO:0006486550.011
cerebellar cortex developmentGO:0021695480.011
microtubule cytoskeleton organizationGO:00002261570.011
t cell differentiation in thymusGO:0033077770.011
divalent inorganic cation transportGO:00725111780.011
regulation of hormone levelsGO:00108172110.011
insulin secretionGO:0030073890.011
membrane organizationGO:00610242450.011
regulation of protein ubiquitinationGO:0031396520.011
positive regulation of epithelial cell proliferationGO:0050679680.011
ribonucleoside catabolic processGO:00424542060.011
connective tissue developmentGO:00614481790.011
epithelial cell developmentGO:00020641590.011
positive regulation of interleukin 6 productionGO:0032755370.011
mapk cascadeGO:00001652810.011
response to acid chemicalGO:00011011110.011
gtp metabolic processGO:00460391440.011
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.010
ion transmembrane transportGO:00342203610.010
lateral inhibitionGO:004633110.010
ribose phosphate metabolic processGO:00196932910.010
regulation of secretion by cellGO:19035302490.010
mrna splicing via spliceosomeGO:0000398430.010
regulation of cellular amino acid metabolic processGO:000652150.010
urogenital system developmentGO:00016552610.010
respiratory system developmentGO:00605411900.010
organophosphate catabolic processGO:00464342320.010
purine nucleoside triphosphate metabolic processGO:00091442260.010
purine ribonucleotide metabolic processGO:00091502900.010
response to organophosphorusGO:0046683220.010
peptidyl proline modificationGO:001820860.010
myeloid cell differentiationGO:00300992330.010
mitotic nuclear divisionGO:0007067480.010

Manf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.069
musculoskeletal system diseaseDOID:1700.069
muscle tissue diseaseDOID:6600.069
muscular diseaseDOID:008000000.069
myopathyDOID:42300.069
connective tissue diseaseDOID:6500.059
bone diseaseDOID:008000100.059
bone development diseaseDOID:008000600.059
limb girdle muscular dystrophyDOID:1172400.015
muscular dystrophyDOID:988400.015
immune system diseaseDOID:291400.013
hematologic cancerDOID:253100.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
immune system cancerDOID:006008300.013
cancerDOID:16200.013