Mus musculus

129 known processes

Cd59a

CD59a antigen

(Aliases: AA987121,Cd59,protectin)

Cd59a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of complement activationGO:004591630.996
negative regulation of protein activation cascadeGO:200025830.995
activation of membrane attack complexGO:000190540.978
protein activation cascadeGO:0072376190.817
activation of immune responseGO:00022531380.795
complement activationGO:0006956160.690
regulation of protein activation cascadeGO:200025770.680
cytokine productionGO:00018163190.542
immune effector processGO:00022523210.527
regulation of acute inflammatory responseGO:0002673270.487
negative regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094860.486
regulation of protein maturationGO:1903317960.444
negative regulation of protein processingGO:0010955790.420
regulation of inflammatory responseGO:00507271470.411
regulation of protein processingGO:0070613960.406
regulation of fibroblast growth factor productionGO:009027040.377
acute inflammatory responseGO:0002526410.360
humoral immune responseGO:0006959570.336
inflammatory responseGO:00069542440.308
negative regulation of protein maturationGO:1903318790.301
protein maturationGO:00516041760.272
negative regulation of immune effector processGO:0002698550.248
protein processingGO:00164851630.243
negative regulation of vasculature developmentGO:1901343260.241
negative regulation of immune system processGO:00026832090.217
regulation of cytokine productionGO:00018172660.205
oxidation reduction processGO:00551143420.195
regulation of cytolysisGO:004226810.180
Mouse
negative regulation of cellular response to growth factor stimulusGO:0090288460.173
cellular response to growth factor stimulusGO:00713631970.151
negative regulation of protein metabolic processGO:00512482820.148
regulation of defense responseGO:00313472330.130
response to growth factorGO:00708481980.127
negative regulation of angiogenesisGO:0016525250.119
cellular response to lipopolysaccharideGO:0071222770.117
cellular amino acid metabolic processGO:00065201030.106
regulation of vasculature developmentGO:1901342880.106
cellular lipid metabolic processGO:00442553230.104
sulfur compound metabolic processGO:00067901000.102
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.091
angiogenesisGO:00015252010.087
negative regulation of cytokine productionGO:0001818840.080
glutathione metabolic processGO:0006749160.070
coagulationGO:0050817780.067
vascular endothelial growth factor receptor signaling pathwayGO:0048010240.065
regulation of cellular response to growth factor stimulusGO:0090287820.062
cytolysisGO:001983580.062
Mouse
cellular amine metabolic processGO:0044106440.061
lipid biosynthetic processGO:00086101790.060
regulation of response to woundingGO:19030341890.058
transmembrane transportGO:00550854120.057
amine metabolic processGO:0009308450.057
leukocyte proliferationGO:00706611720.056
cellular ketone metabolic processGO:0042180840.055
regulation of cellular amino acid metabolic processGO:000652150.055
cellular chemical homeostasisGO:00550822150.055
regulation of cellular ketone metabolic processGO:0010565660.053
cellular response to biotic stimulusGO:0071216920.051
nucleobase containing small molecule metabolic processGO:00550863520.047
response to molecule of bacterial originGO:00022371430.047
regulation of humoral immune responseGO:0002920220.045
regulation of cell activationGO:00508652890.045
cellular amide metabolic processGO:0043603580.043
cellular response to molecule of bacterial originGO:0071219830.043
response to organic cyclic compoundGO:00140701980.043
t cell activationGO:00421102890.042
lipid catabolic processGO:0016042690.041
regulation of leukocyte proliferationGO:00706631210.040
sterol metabolic processGO:0016125580.040
regulation of blood coagulationGO:0030193280.040
cdc42 protein signal transductionGO:003248800.039
negative regulation of phosphorus metabolic processGO:00105631840.039
regulation of cellular amine metabolic processGO:0033238200.039
g protein coupled receptor signaling pathwayGO:00071862430.038
regulation of lymphocyte activationGO:00512492400.038
peptide metabolic processGO:0006518460.037
xenobiotic catabolic processGO:004217810.037
cellular response to lipidGO:00713961450.037
divalent inorganic cation homeostasisGO:00725071380.035
regulation of t cell activationGO:00508631700.035
regulation of plasma lipoprotein particle levelsGO:0097006230.034
positive regulation of cellular amine metabolic processGO:003324050.034
positive regulation of protein phosphorylationGO:00019342420.034
small molecule catabolic processGO:0044282710.034
cholesterol metabolic processGO:0008203560.034
mapk cascadeGO:00001652810.033
leukocyte differentiationGO:00025213420.033
response to acid chemicalGO:00011011110.033
regulation of protein kinase activityGO:00458592320.033
production of molecular mediator of immune responseGO:00024401030.033
small molecule biosynthetic processGO:00442831320.032
sterol homeostasisGO:0055092450.032
cd4 positive alpha beta t cell cytokine productionGO:003574340.031
response to lipopolysaccharideGO:00324961280.031
glycerolipid metabolic processGO:00464861220.031
regulation of reactive oxygen species metabolic processGO:2000377400.031
cation homeostasisGO:00550802120.031
regulation of protein serine threonine kinase activityGO:00719001570.030
regulation of mapk cascadeGO:00434082480.030
positive regulation of cell developmentGO:00107202370.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
organic cyclic compound catabolic processGO:19013612950.030
acylglycerol metabolic processGO:0006639550.030
carboxylic acid biosynthetic processGO:0046394860.030
cellular response to organonitrogen compoundGO:00714171450.030
nucleoside phosphate metabolic processGO:00067533380.030
fatty acid metabolic processGO:00066311210.029
regulation of body fluid levelsGO:00508781620.029
response to nitrosative stressGO:005140910.029
glycerolipid biosynthetic processGO:0045017500.029
cellular modified amino acid metabolic processGO:0006575630.028
dna metabolic processGO:00062593030.028
negative regulation of cellular protein metabolic processGO:00322692470.028
response to oxidative stressGO:00069791230.028
unsaturated fatty acid metabolic processGO:0033559310.028
regulation of transmembrane transportGO:00347621280.028
organonitrogen compound biosynthetic processGO:19015661920.028
negative regulation of phosphorylationGO:00423261660.028
neutral lipid metabolic processGO:0006638570.028
regulation of cellular catabolic processGO:00313292420.027
regulation of transferase activityGO:00513382630.027
negative regulation of molecular functionGO:00440922580.027
cellular ion homeostasisGO:00068731650.027
blood coagulationGO:0007596760.027
cellular response to acid chemicalGO:0071229680.026
positive regulation of mapk cascadeGO:00434101700.026
adaptive immune responseGO:00022501550.026
membrane organizationGO:00610242450.026
response to organonitrogen compoundGO:00102432460.026
regulation of complement activation classical pathwayGO:003045010.026
cellular lipid catabolic processGO:0044242520.025
positive regulation of reactive oxygen species metabolic processGO:2000379110.025
cellular calcium ion homeostasisGO:00068741190.025
intracellular protein transportGO:00068862040.025
striated muscle tissue developmentGO:00147062930.025
regulation of t cell proliferationGO:0042129920.025
regulation of kinase activityGO:00435492490.025
organic acid biosynthetic processGO:0016053860.025
organic hydroxy compound catabolic processGO:1901616250.024
positive regulation of cell activationGO:00508671580.024
myeloid cell differentiationGO:00300992330.024
regulation of ion transportGO:00432692150.024
positive regulation of t cell activationGO:00508701010.024
cellular homeostasisGO:00197252400.024
monocarboxylic acid metabolic processGO:00327871910.024
endomembrane system organizationGO:00102561470.023
positive regulation of lymphocyte activationGO:00512511400.023
cytoplasmic transportGO:00164822340.023
regulation of leukocyte mediated immunityGO:00027031040.023
reactive oxygen species metabolic processGO:0072593840.023
renal system developmentGO:00720012250.023
carbohydrate derivative biosynthetic processGO:19011371830.023
lymphocyte mediated immunityGO:00024491390.023
reverse cholesterol transportGO:004369160.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.023
nucleotide metabolic processGO:00091173320.022
cell type specific apoptotic processGO:00972852680.022
b cell mediated immunityGO:0019724710.022
t cell proliferationGO:00420981200.022
male gamete generationGO:00482322850.022
chemotaxisGO:00069352470.022
cholesterol homeostasisGO:0042632440.022
anion transportGO:00068201770.022
positive regulation of ion transportGO:0043270650.022
positive regulation of protein modification processGO:00314012990.021
wound healingGO:00420601570.021
regulation of lipid metabolic processGO:00192161180.021
negative regulation of protein modification processGO:00314001630.021
actin cytoskeleton organizationGO:00300362200.021
regulation of hormone levelsGO:00108172110.021
cation transportGO:00068123990.021
regulation of beta amyloid clearanceGO:190022110.021
lipid homeostasisGO:0055088630.020
regulation of map kinase activityGO:00434051200.020
positive regulation of lipid metabolic processGO:0045834400.020
negative regulation of protein serine threonine kinase activityGO:0071901490.020
negative regulation of intracellular signal transductionGO:19025321670.020
alcohol metabolic processGO:00060661160.020
regulation of lymphocyte mediated immunityGO:0002706840.020
regulation of multi organism processGO:00439001110.020
multicellular organismal signalingGO:0035637910.020
acylglycerol biosynthetic processGO:0046463180.019
fatty acid derivative metabolic processGO:1901568330.019
regulation of protein localizationGO:00328802310.019
gland developmentGO:00487323300.019
fat cell differentiationGO:00454441600.019
plasma membrane organizationGO:0007009900.019
skeletal system developmentGO:00015013560.019
positive regulation of cytokine productionGO:00018191740.019
muscle cell differentiationGO:00426922610.019
negative regulation of phosphate metabolic processGO:00459361840.019
small gtpase mediated signal transductionGO:0007264970.019
positive regulation of lymphocyte proliferationGO:0050671700.019
regulation of hemostasisGO:1900046280.018
lymphocyte proliferationGO:00466511640.018
regulation of neuron differentiationGO:00456642810.018
leukocyte mediated immunityGO:00024431740.018
positive regulation of transferase activityGO:00513471670.018
negative regulation of protein phosphorylationGO:00019331260.018
organophosphate biosynthetic processGO:00904071220.018
nitrobenzene metabolic processGO:001891610.018
ribose phosphate metabolic processGO:00196932910.018
developmental growth involved in morphogenesisGO:00605601380.018
regulation of apoptotic signaling pathwayGO:20012331970.018
positive regulation of membrane protein ectodomain proteolysisGO:005104430.018
protein localization to organelleGO:00333651850.018
cholesterol esterificationGO:003443530.017
negative regulation of dendritic spine developmentGO:006100030.017
cell activation involved in immune responseGO:00022631260.017
cellular metal ion homeostasisGO:00068751510.017
peptidyl amino acid modificationGO:00181933360.017
ribonucleotide metabolic processGO:00092592910.017
developmental maturationGO:00217001930.017
regulation of coagulationGO:0050818310.017
phospholipid metabolic processGO:0006644870.017
alpha beta t cell activationGO:0046631910.017
response to extracellular stimulusGO:00099911270.017
posttranscriptional regulation of gene expressionGO:00106081550.017
regulation of cell projection organizationGO:00313442060.017
regulation of membrane potentialGO:00423911920.017
t cell mediated immunityGO:0002456500.017
homeostasis of number of cellsGO:00488722100.017
organic hydroxy compound metabolic processGO:19016152030.016
lipoprotein metabolic processGO:0042157430.016
mitochondrion organizationGO:00070051340.016
tissue homeostasisGO:00018941150.016
hemostasisGO:0007599780.016
regulation of proteolysisGO:00301621640.016
regulation of lymphocyte proliferationGO:00506701170.016
defense response to other organismGO:00985421970.016
regulation of intracellular transportGO:00323861590.016
innate immune responseGO:00450871570.016
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.016
negative regulation of blood vessel endothelial cell migrationGO:004353730.016
regulation of tumor necrosis factor productionGO:0032680490.016
steroid esterificationGO:003443330.016
protein modification by small protein conjugation or removalGO:00706472070.016
negative regulation of kinase activityGO:0033673810.016
nitrogen compound transportGO:00717052710.016
response to reactive oxygen speciesGO:0000302560.016
myeloid leukocyte differentiationGO:00025731190.016
regulation of phospholipid effluxGO:190299420.015
blood circulationGO:00080151950.015
dendritic spine maintenanceGO:009706240.015
synaptic transmissionGO:00072683290.015
carbohydrate biosynthetic processGO:0016051740.015
inorganic cation transmembrane transportGO:00986622070.015
regulation of homeostatic processGO:00328441820.015
sterol transportGO:0015918380.015
negative regulation of transferase activityGO:0051348850.015
triglyceride metabolic processGO:0006641510.015
negative regulation of sterol transportGO:003237240.015
blood vessel morphogenesisGO:00485142850.015
regulation of cell motilityGO:20001452360.015
sensory organ morphogenesisGO:00905962420.015
carbohydrate metabolic processGO:00059752300.015
cation transmembrane transportGO:00986552660.015
chromatin organizationGO:00063252060.015
negative regulation of cholesterol transportGO:003237540.015
monocarboxylic acid biosynthetic processGO:0072330610.015
cellular response to hormone stimulusGO:00328701500.015
cognitionGO:00508901490.014
fertilizationGO:00095661270.014
protein targetingGO:00066051430.014
cholesterol transportGO:0030301380.014
positive regulation of protein kinase activityGO:00458601440.014
apoptotic signaling pathwayGO:00971903060.014
icosanoid metabolic processGO:0006690330.014
skeletal muscle organ developmentGO:00605381630.014
ventricular cardiac muscle cell action potentialGO:008600540.014
organic anion transportGO:00157111370.014
rho protein signal transductionGO:0007266320.014
camera type eye developmentGO:00430102660.014
protein catabolic processGO:00301632210.014
purine ribonucleotide metabolic processGO:00091502900.014
high density lipoprotein particle remodelingGO:003437540.014
response to steroid hormoneGO:0048545560.014
regulation of secretion by cellGO:19035302490.014
negative regulation of proteolysisGO:0045861740.014
lymphocyte activation involved in immune responseGO:0002285930.014
response to inorganic substanceGO:0010035960.014
regulation of adaptive immune responseGO:0002819900.014
plasma lipoprotein particle clearanceGO:0034381130.014
benzene containing compound metabolic processGO:004253750.013
response to nutrient levelsGO:00316671090.013
ion transmembrane transportGO:00342203610.013
positive regulation of nervous system developmentGO:00519622210.013
monocyte chemotactic protein 1 productionGO:007160510.013
protein localization to membraneGO:00726571080.013
glycerolipid catabolic processGO:0046503160.013
protein lipid complex subunit organizationGO:0071825120.013
stem cell differentiationGO:00488632680.013
ras protein signal transductionGO:0007265770.013
negative regulation of map kinase activityGO:0043407340.013
lymphocyte differentiationGO:00300982420.013
cell recognitionGO:0008037830.013
leukocyte activation involved in immune responseGO:00023661260.013
hematopoietic progenitor cell differentiationGO:00022441430.013
organelle fissionGO:00482851700.013
metal ion homeostasisGO:00550651890.013
digestive tract developmentGO:00485651900.013
negative regulation of cell proliferationGO:00082852960.013
macromolecule catabolic processGO:00090572810.013
nuclear divisionGO:00002801580.013
neuron deathGO:00709971540.013
alcohol catabolic processGO:0046164160.013
positive regulation of immune effector processGO:00026991070.013
negative regulation of mapk cascadeGO:0043409650.013
cellular response to abiotic stimulusGO:0071214560.013
proteasomal protein catabolic processGO:0010498980.013
mitotic cell cycle processGO:19030471590.012
purine nucleotide metabolic processGO:00061633020.012
single fertilizationGO:0007338820.012
glucose homeostasisGO:00425931280.012
circulatory system processGO:00030131970.012
iron ion homeostasisGO:0055072360.012
positive regulation of cell deathGO:00109422240.012
myeloid cell homeostasisGO:00022621140.012
reactive nitrogen species metabolic processGO:200105700.012
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.012
purine containing compound metabolic processGO:00725213110.012
muscle tissue developmentGO:00605373080.012
oligopeptide transmembrane transportGO:003567240.012
lipid modificationGO:0030258650.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
inorganic ion transmembrane transportGO:00986602340.012
establishment of protein localization to organelleGO:00725941180.012
kidney developmentGO:00018222130.012
cytokine mediated signaling pathwayGO:00192211150.012
cytokine production involved in immune responseGO:0002367340.012
plasma lipoprotein particle organizationGO:0071827110.012
positive regulation of defense responseGO:00313491240.012
superoxide metabolic processGO:0006801270.012
ear developmentGO:00435832000.012
positive regulation of cellular ph reductionGO:003284920.012
action potentialGO:0001508780.012
regulation of organelle organizationGO:00330432890.012
protein oligomerizationGO:0051259670.012
sensory perceptionGO:00076002450.012
learning or memoryGO:00076111480.012
glycosylationGO:0070085620.012
regulation of bindingGO:00510981110.012
lipid localizationGO:00108761260.012
spermatid differentiationGO:00485151150.012
neuronal action potentialGO:0019228540.012
positive regulation of protein serine threonine kinase activityGO:00719021060.011
protein modification by small protein conjugationGO:00324461870.011
glycerophospholipid metabolic processGO:0006650710.011
transition metal ion homeostasisGO:0055076540.011
negative regulation of growthGO:0045926990.011
nucleocytoplasmic transportGO:00069131390.011
defense response to bacteriumGO:00427421190.011
cell cell recognitionGO:0009988440.011
cellular response to organic cyclic compoundGO:0071407870.011
positive regulation of kinase activityGO:00336741550.011
neuron apoptotic processGO:00514021420.011
forebrain developmentGO:00309003020.011
spermatogenesisGO:00072832840.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
phospholipid effluxGO:003370030.011
neutral lipid biosynthetic processGO:0046460180.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
response to metal ionGO:0010038470.011
cofactor metabolic processGO:0051186800.011
urogenital system developmentGO:00016552610.011
protein ubiquitinationGO:00165671710.011
ossificationGO:00015032160.011
i kappab kinase nf kappab signalingGO:0007249850.011
muscle contractionGO:00069361010.011
positive regulation of innate immune responseGO:0045089800.011
cytokine metabolic processGO:0042107710.011
negative regulation of cellular amine metabolic processGO:003323910.011
regulation of protein transportGO:00512231630.011
lipoprotein biosynthetic processGO:0042158330.011
organic hydroxy compound transportGO:0015850930.011
monocarboxylic acid transportGO:0015718440.011
cellular nitrogen compound catabolic processGO:00442702800.011
rhythmic processGO:00485111740.011
regulation of membrane protein ectodomain proteolysisGO:005104330.011
positive regulation of cellular catabolic processGO:00313311480.011
fatty acid biosynthetic processGO:0006633410.011
cardiac muscle cell contractionGO:008600370.011
cell maturationGO:00484691270.011
peptidyl tyrosine phosphorylationGO:00181081430.011
skin developmentGO:00435882200.011
regulation of wound healingGO:0061041400.011
positive regulation of phagocytosis engulfmentGO:006010030.011
regulation of protein kinase b signalingGO:0051896560.011
leukocyte migrationGO:00509001240.011
water soluble vitamin metabolic processGO:0006767100.011
regulation of chloride transportGO:200122520.011
digestive system developmentGO:00551232000.011
dephosphorylationGO:00163111290.011
regulation of phospholipid transportGO:200113840.011
innate immune response in mucosaGO:000222730.011
erythrocyte differentiationGO:0030218880.010
regulation of cellular response to stressGO:00801351590.010
positive regulation of map kinase activityGO:0043406840.010
hexose metabolic processGO:0019318980.010
maintenance of locationGO:0051235890.010
positive regulation of leukocyte proliferationGO:0070665730.010
regulation of purine nucleotide metabolic processGO:19005421690.010
acylglycerol homeostasisGO:0055090160.010
acylglycerol catabolic processGO:0046464110.010
microtubule based processGO:00070172360.010
sodium ion export from cellGO:003637610.010
vitamin metabolic processGO:0006766230.010
positive regulation of nucleotide metabolic processGO:00459811140.010
ribonucleoside metabolic processGO:00091192450.010
myelinationGO:0042552740.010
cellular response to external stimulusGO:0071496880.010
response to amino acidGO:0043200370.010
purine containing compound biosynthetic processGO:0072522700.010
cellular macromolecule catabolic processGO:00442652060.010
immune response regulating signaling pathwayGO:00027641250.010
wnt signaling pathwayGO:00160551880.010
tumor necrosis factor productionGO:0032640500.010
interleukin 1 productionGO:0032612310.010
multicellular organismal homeostasisGO:00488711640.010
regulation of establishment of protein localizationGO:00702011810.010
tumor necrosis factor superfamily cytokine productionGO:0071706510.010
anatomical structure homeostasisGO:00602491450.010
skeletal system morphogenesisGO:00487052030.010
glycoprotein metabolic processGO:00091001160.010
stress activated mapk cascadeGO:0051403800.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
regulation of cell growthGO:0001558910.010
mitotic cytokinesisGO:000028140.010

Cd59a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.034
inherited metabolic disorderDOID:65500.034
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.034
cardiovascular system diseaseDOID:128700.031
central nervous system diseaseDOID:33100.024
immune system diseaseDOID:291400.021
musculoskeletal system diseaseDOID:1700.020
sensory system diseaseDOID:005015500.018
retinal diseaseDOID:567900.017
eye diseaseDOID:561400.017
eye and adnexa diseaseDOID:149200.017
lipid metabolism disorderDOID:314600.016
hematopoietic system diseaseDOID:7400.016
myopathyDOID:42300.016
muscular diseaseDOID:008000000.016
muscle tissue diseaseDOID:6600.016
cardiomyopathyDOID:005070000.014
heart diseaseDOID:11400.014
neurodegenerative diseaseDOID:128900.013
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
intrinsic cardiomyopathyDOID:006003600.013
retinal degenerationDOID:846600.012
anemiaDOID:235500.010