Mus musculus

360 known processes

Cdkn2a

cyclin-dependent kinase inhibitor 2A

(Aliases: p16INK4a,MTS1,p16,Pctr1,INK4a-ARF,Ink4a/Arf,p16(INK4a),ARF-INK4a,Arf,p19ARF,p19<ARF>)

Cdkn2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell cycleGO:00457861230.981
regulation of cell cycleGO:00517262810.978
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.967
negative regulation of cell proliferationGO:00082852960.965
skeletal system developmentGO:00015013560.949
regulation of protein kinase activityGO:00458592320.920
cell cycle arrestGO:0007050370.882
axon guidanceGO:00074111410.842
signal transduction by p53 class mediatorGO:0072331510.841
intrinsic apoptotic signaling pathwayGO:00971931320.836
gland developmentGO:00487323300.825
regulation of cell morphogenesis involved in differentiationGO:00107691510.799
cellular response to dna damage stimulusGO:00069742070.792
regulation of kinase activityGO:00435492490.785
regulation of cell cycle processGO:00105641600.749
Human Mouse
segmentationGO:0035282930.743
regulation of synaptic plasticityGO:0048167870.671
male gamete generationGO:00482322850.666
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.661
Human
positive regulation of cell developmentGO:00107202370.656
appendage morphogenesisGO:00351071490.632
cellular ketone metabolic processGO:0042180840.631
cell growthGO:00160491300.628
cellular amino acid metabolic processGO:00065201030.608
apoptotic signaling pathwayGO:00971903060.606
regionalizationGO:00030023370.601
cellular amine metabolic processGO:0044106440.598
regulation of reactive oxygen species metabolic processGO:2000377400.596
cellular response to growth factor stimulusGO:00713631970.591
Human
positive regulation of nervous system developmentGO:00519622210.591
negative regulation of growthGO:0045926990.579
neuron projection guidanceGO:00974851410.563
mitotic cell cycleGO:00002781950.558
Human Mouse
axonogenesisGO:00074092740.550
germ cell developmentGO:00072811850.536
positive regulation of cellular amine metabolic processGO:003324050.522
negative regulation of immune system processGO:00026832090.506
myeloid cell differentiationGO:00300992330.502
Human
embryonic organ morphogenesisGO:00485622760.502
developmental maturationGO:00217001930.498
regulation of cellular amine metabolic processGO:0033238200.495
spermatogenesisGO:00072832840.494
regulation of organ morphogenesisGO:20000271440.491
regulation of transferase activityGO:00513382630.491
positive regulation of cell cycleGO:0045787920.486
dna recombinationGO:0006310920.484
regulation of mitotic cell cycleGO:00073461260.481
Human Mouse
positive regulation of apoptotic processGO:00430652170.468
carbon catabolite activation of transcriptionGO:004599140.467
collagen fibril organizationGO:0030199320.464
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.452
Human
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.446
nuclear divisionGO:00002801580.440
odontogenesis of dentin containing toothGO:0042475660.436
jnk cascadeGO:0007254720.429
telencephalon developmentGO:00215371860.428
oocyte differentiationGO:0009994350.427
negative regulation of epithelial cell proliferationGO:0050680640.427
mitotic g1 dna damage checkpointGO:003157140.424
stem cell proliferationGO:00720891170.419
oocyte axis specificationGO:000730920.418
epithelial cell maturation involved in prostate gland developmentGO:006074340.415
response to growth factorGO:00708481980.411
Human
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.410
positive regulation of cellular amino acid metabolic processGO:004576430.406
regulation of stress activated mapk cascadeGO:0032872690.403
meiotic cell cycleGO:00513211220.402
glycosyl compound catabolic processGO:19016582060.401
negative regulation of kinase activityGO:0033673810.397
mesenchyme developmentGO:00604851520.396
ras protein signal transductionGO:0007265770.392
embryonic appendage morphogenesisGO:00351131260.388
positive regulation of keratinocyte proliferationGO:001083840.386
hippocampus developmentGO:0021766520.383
positive regulation of cell deathGO:00109422240.378
positive regulation of mitotic cell cycleGO:0045931410.362
negative regulation of phosphorus metabolic processGO:00105631840.362
regulation of cellular catabolic processGO:00313292420.358
pole plasm assemblyGO:000731520.355
regulation of cell divisionGO:0051302760.354
g1 s transition of mitotic cell cycleGO:0000082570.340
Mouse
embryonic skeletal system developmentGO:00487061200.340
negative regulation of molecular functionGO:00440922580.340
stem cell developmentGO:00488642190.334
cell fate commitmentGO:00451652100.333
myeloid leukocyte differentiationGO:00025731190.331
regulation of cell growthGO:0001558910.325
pyramidal neuron migrationGO:002185210.316
response to x rayGO:0010165110.315
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.314
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.311
peptidyl tyrosine modificationGO:00182121450.309
regulation of neuron projection developmentGO:00109751690.309
signal transduction involved in dna integrity checkpointGO:007240130.309
b cell differentiationGO:0030183780.306
regulation of cellular amino acid metabolic processGO:000652150.305
columnar cuboidal epithelial cell differentiationGO:0002065820.303
organelle fissionGO:00482851700.303
dna metabolic processGO:00062593030.302
leukocyte differentiationGO:00025213420.300
signal transduction involved in dna damage checkpointGO:007242230.299
regulation of cell cycle arrestGO:0071156120.294
ameboidal type cell migrationGO:00016671280.293
negative regulation of leukocyte differentiationGO:1902106510.293
negative regulation of cell cycle phase transitionGO:1901988480.292
Human Mouse
lymphocyte differentiationGO:00300982420.289
positive regulation of growthGO:00459271040.286
negative regulation of lymphocyte activationGO:0051250910.286
cell divisionGO:00513011200.280
appendage developmentGO:00487361660.279
developmental programmed cell deathGO:0010623410.277
response to nutrient levelsGO:00316671090.275
Human
positive regulation of apoptotic signaling pathwayGO:2001235950.275
camera type eye developmentGO:00430102660.275
female sex differentiationGO:0046660840.273
retinal ganglion cell axon guidanceGO:0031290180.270
dendrite developmentGO:00163581150.269
endochondral bone morphogenesisGO:0060350500.269
regulation of erythrocyte differentiationGO:0045646230.269
regulation of mapk cascadeGO:00434082480.268
reactive oxygen species metabolic processGO:0072593840.266
nephron morphogenesisGO:0072028690.265
morphogenesis of a branching structureGO:00017632030.262
chromatin organizationGO:00063252060.259
regulation of angiogenesisGO:0045765810.255
ossificationGO:00015032160.255
regulation of t cell differentiationGO:0045580830.254
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.253
cellular senescenceGO:0090398110.251
positive regulation of auditory receptor cell differentiationGO:004560910.250
actin filament organizationGO:00070151130.250
transforming growth factor beta receptor signaling pathwayGO:0007179710.249
Human
peptidyl amino acid modificationGO:00181933360.249
cellular response to external stimulusGO:0071496880.247
Human
central nervous system neuron differentiationGO:00219531620.247
signal transduction involved in cell cycle checkpointGO:007239530.246
regulation of neuron differentiationGO:00456642810.244
gtp catabolic processGO:00061841430.244
lung inductionGO:006049230.243
meiotic nuclear divisionGO:00071261150.238
posttranscriptional regulation of gene expressionGO:00106081550.237
ureteric bud morphogenesisGO:0060675620.236
developmental growth involved in morphogenesisGO:00605601380.234
regulation of epithelial cell proliferation involved in prostate gland developmentGO:0060768100.231
meiosis iGO:0007127600.231
regulation of intracellular transportGO:00323861590.231
cell adhesionGO:00071553290.228
angiogenesisGO:00015252010.226
regulation of leukocyte differentiationGO:19021051590.225
auditory receptor cell fate specificationGO:004266710.223
regulation of mitosisGO:0007088290.222
negative regulation of cellular catabolic processGO:0031330470.221
response to oxygen levelsGO:0070482620.221
stem cell differentiationGO:00488632680.220
regulation of epithelial cell proliferationGO:00506781410.218
regulation of cell projection organizationGO:00313442060.216
regulation of apoptotic signaling pathwayGO:20012331970.214
regulation of vasculature developmentGO:1901342880.211
regulation of cell motilityGO:20001452360.211
epithelium migrationGO:0090132630.210
regulation of cell substrate adhesionGO:0010810730.210
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225520.208
male sex differentiationGO:00466611090.206
negative regulation of cellular protein metabolic processGO:00322692470.206
cell type specific apoptotic processGO:00972852680.205
mesenchymal cell developmentGO:0014031930.204
oviduct developmentGO:006006630.204
epithelial cell developmentGO:00020641590.202
organ growthGO:00352651170.202
mesonephric tubule developmentGO:0072164940.202
negative regulation of intracellular signal transductionGO:19025321670.199
negative regulation of mitotic cell cycle phase transitionGO:1901991450.199
Human Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.198
response to extracellular stimulusGO:00099911270.197
Human
regulation of cytoskeleton organizationGO:00514931220.196
response to organic cyclic compoundGO:00140701980.196
regulation of neuron apoptotic processGO:00435231220.196
ribonucleoside catabolic processGO:00424542060.196
regulation of ras protein signal transductionGO:00465781140.195
regulation of peptide secretionGO:0002791770.192
negative regulation of fibroblast proliferationGO:0048147140.192
mitral valve developmentGO:000317440.191
regulation of ras gtpase activityGO:0032318880.189
regulation of cell sizeGO:0008361720.188
signal transduction involved in mitotic dna damage checkpointGO:190240230.187
schwann cell proliferationGO:001401020.187
positive regulation of protein phosphorylationGO:00019342420.186
neuroblast differentiationGO:001401620.186
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076310.186
neuron deathGO:00709971540.185
endothelial cell migrationGO:0043542440.185
nephron tubule morphogenesisGO:0072078680.184
wound healingGO:00420601570.184
stem cell maintenanceGO:00198271300.182
positive regulation of cell cycle processGO:0090068610.181
heterocycle catabolic processGO:00467002800.181
response to decreased oxygen levelsGO:0036293590.180
negative regulation of t cell proliferationGO:0042130380.179
limb morphogenesisGO:00351081490.179
pallium developmentGO:00215431200.179
homeostasis of number of cellsGO:00488722100.178
regulation of map kinase activityGO:00434051200.177
protein modification by small protein conjugation or removalGO:00706472070.177
regulation of protein stabilityGO:0031647520.177
somite developmentGO:0061053810.176
regulation of nucleocytoplasmic transportGO:0046822730.176
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.175
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.175
forebrain neuron developmentGO:0021884300.175
mesenchymal cell differentiationGO:00487621070.175
positive regulation of stem cell differentiationGO:2000738230.174
odontogenesisGO:0042476780.173
regulation of cellular response to stressGO:00801351590.173
male gonad developmentGO:0008584880.172
positive regulation of neuron projection developmentGO:0010976790.172
response to radiationGO:00093141650.172
positive regulation of neuron differentiationGO:00456661410.172
limb developmentGO:00601731660.172
regulation of cell cycle phase transitionGO:1901987770.171
Human Mouse
limbic system developmentGO:0021761720.170
positive regulation of inner ear receptor cell differentiationGO:200098210.169
auditory receptor cell fate determinationGO:004266830.169
regulation of protein serine threonine kinase activityGO:00719001570.167
cellular nitrogen compound catabolic processGO:00442702800.166
somitogenesisGO:0001756690.166
activation of adenylate cyclase activityGO:000719040.166
chemotaxisGO:00069352470.165
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.165
regulation of cellular ketone metabolic processGO:0010565660.163
sprouting angiogenesisGO:0002040260.163
dna damage response signal transduction by p53 class mediatorGO:0030330190.162
embryonic limb morphogenesisGO:00303261260.161
carbohydrate derivative catabolic processGO:19011362310.160
regulation of mast cell differentiationGO:006037530.159
purine nucleotide metabolic processGO:00061633020.159
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.157
multicellular organism growthGO:00352641610.157
blood vessel morphogenesisGO:00485142850.157
nephron tubule developmentGO:0072080840.156
response to transforming growth factor betaGO:0071559880.155
Human
oogenesisGO:0048477560.155
paraxial mesodermal cell differentiationGO:004834220.155
negative regulation of stem cell proliferationGO:2000647120.155
aortic valve morphogenesisGO:000318040.153
meiotic cell cycle processGO:1903046770.152
stem cell divisionGO:0017145300.151
spermatid differentiationGO:00485151150.151
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.151
tube closureGO:0060606910.151
notch signaling pathwayGO:0007219710.150
lens development in camera type eyeGO:0002088620.150
positive regulation of lymphocyte apoptotic processGO:0070230130.149
positive regulation of organelle organizationGO:00106381280.149
peptidyl tyrosine phosphorylationGO:00181081430.149
t cell differentiation in thymusGO:0033077770.148
negative regulation of nuclear divisionGO:0051784190.147
mesenchyme morphogenesisGO:0072132320.147
nuclear transportGO:00511691390.147
negative regulation of cell growthGO:0030308440.146
ribonucleotide metabolic processGO:00092592910.146
regulation of kidney developmentGO:0090183400.146
embryonic skeletal system morphogenesisGO:0048704910.144
protein localization to organelleGO:00333651850.144
nucleoside phosphate metabolic processGO:00067533380.143
blastocyst developmentGO:0001824800.143
phenol containing compound metabolic processGO:0018958600.143
regulation of actin filament bundle assemblyGO:0032231180.142
regulation of stem cell differentiationGO:2000736500.141
regulation of hydrolase activityGO:00513362460.141
morphogenesis of a branching epitheliumGO:00611381930.141
negative regulation of phosphorylationGO:00423261660.140
sensory organ morphogenesisGO:00905962420.139
tertiary branching involved in mammary gland duct morphogenesisGO:006074830.139
oocyte constructionGO:000730820.138
skeletal system morphogenesisGO:00487052030.138
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.137
Human
regulation of cellular response to growth factor stimulusGO:0090287820.136
Human
cardiac muscle tissue developmentGO:00487381300.136
organic cyclic compound catabolic processGO:19013612950.135
ear morphogenesisGO:00424711180.134
rhythmic processGO:00485111740.134
regulation of cell cycle g1 s phase transitionGO:1902806350.132
Mouse
morphogenesis of a polarized epitheliumGO:0001738370.130
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.129
nucleocytoplasmic transportGO:00069131390.129
chondrocyte differentiationGO:0002062720.128
cytokine productionGO:00018163190.128
positive regulation of transferase activityGO:00513471670.128
nucleotide catabolic processGO:00091662170.127
positive regulation of protein modification processGO:00314012990.127
t cell selectionGO:0045058340.127
neuron apoptotic processGO:00514021420.127
extracellular structure organizationGO:00430621480.126
regulation of cellular component biogenesisGO:00440871810.126
regulation of rho gtpase activityGO:0032319580.126
cation transportGO:00068123990.126
development of primary female sexual characteristicsGO:0046545730.125
negative regulation of phosphate metabolic processGO:00459361840.124
erythrocyte differentiationGO:0030218880.122
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.122
extrinsic apoptotic signaling pathwayGO:00971911260.121
regulation of organelle organizationGO:00330432890.121
regulation of lymphocyte differentiationGO:00456191070.121
protein maturationGO:00516041760.120
neural tube developmentGO:00219151600.120
ovulation cycleGO:0042698590.120
actin filament bundle assemblyGO:0051017400.120
kidney morphogenesisGO:0060993830.120
negative regulation of transferase activityGO:0051348850.119
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.118
positive regulation of map kinase activityGO:0043406840.118
tissue migrationGO:0090130680.118
embryonic axis specificationGO:0000578300.118
cardiac right ventricle formationGO:000321930.117
positive regulation of chromosome organizationGO:2001252330.117
nucleobase containing small molecule metabolic processGO:00550863520.116
fibroblast growth factor receptor signaling pathwayGO:0008543460.116
maternal determination of anterior posterior axis embryoGO:000835820.115
glycosyl compound metabolic processGO:19016572460.114
protein targetingGO:00066051430.114
positive regulation of exit from mitosisGO:003153610.113
hormone secretionGO:00468791280.113
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.112
muscle cell differentiationGO:00426922610.112
forebrain developmentGO:00309003020.112
mitotic cell cycle processGO:19030471590.112
Human Mouse
negative regulation of cell motilityGO:2000146610.112
b cell activationGO:00421131610.112
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.111
heart formationGO:0060914160.111
positive regulation of kinase activityGO:00336741550.110
cell maturationGO:00484691270.110
positive regulation of protein serine threonine kinase activityGO:00719021060.110
protein localization to nucleusGO:00345041210.110
negative regulation of cell cycle processGO:0010948690.109
Human Mouse
digestive system developmentGO:00551232000.109
mammary gland morphogenesisGO:0060443540.109
nucleoside phosphate catabolic processGO:19012922220.109
female gamete generationGO:0007292740.108
positive regulation of camp biosynthetic processGO:0030819190.108
negative regulation of neuron apoptotic processGO:0043524920.107
embryonic digit morphogenesisGO:0042733560.107
primary neural tube formationGO:0014020950.107
female genitalia morphogenesisGO:004880730.106
blood vessel endothelial cell migrationGO:0043534230.106
oocyte developmentGO:0048599330.106
development of primary male sexual characteristicsGO:0046546880.106
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.105
digestive tract developmentGO:00485651900.105
kidney epithelium developmentGO:00720731210.105
t cell proliferationGO:00420981200.105
cerebellum developmentGO:0021549770.104
positive regulation of epithelial cell proliferationGO:0050679680.104
organonitrogen compound catabolic processGO:19015652640.104
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.104
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.103
fibroblast proliferationGO:0048144350.102
anatomical structure homeostasisGO:00602491450.102
regulation of neuron deathGO:19012141340.102
positive regulation of cellular catabolic processGO:00313311480.101
neural tube closureGO:0001843900.101
regulation of cell migrationGO:00303342190.101
signal transduction involved in mitotic cell cycle checkpointGO:007241330.101
hemangioblast cell differentiationGO:006021710.101
megakaryocyte differentiationGO:0030219260.100
Human
pancreatic pp cell fate commitmentGO:000332920.100
astrocyte fate commitmentGO:006001840.100
positive regulation of cytokine productionGO:00018191740.100
gastrulationGO:00073691160.100
regulation of mitotic cell cycle phase transitionGO:1901990730.099
Human Mouse
central nervous system neuron developmentGO:0021954670.099
phenol containing compound biosynthetic processGO:0046189210.099
actin cytoskeleton organizationGO:00300362200.099
covalent chromatin modificationGO:00165691630.099
cloacal septationGO:006019720.098
response to endoplasmic reticulum stressGO:0034976530.098
negative regulation of odontogenesisGO:004248330.097
regulation of anatomical structure sizeGO:00900661780.097
neuroblast proliferationGO:0007405490.097
nephric duct formationGO:007217940.097
regulation of histone modificationGO:0031056560.096
negative regulation of protein metabolic processGO:00512482820.096
urogenital system developmentGO:00016552610.096
regulation of peptidyl tyrosine phosphorylationGO:0050730930.096
pituitary gland developmentGO:0021983380.096
mitral valve morphogenesisGO:000318340.096
regulation of chromatin organizationGO:1902275570.095
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:200076410.095
gonad developmentGO:00084061410.095
regulation of rho protein signal transductionGO:0035023710.094
guanosine containing compound metabolic processGO:19010681440.094
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.094
heart morphogenesisGO:00030071780.094
negative regulation of epithelial cell proliferation involved in prostate gland developmentGO:006077070.093
germ line stem cell divisionGO:004207820.093
purine ribonucleoside catabolic processGO:00461302050.093
regulation of fibroblast proliferationGO:0048145340.092
skeletal muscle cell differentiationGO:0035914660.092
female genitalia developmentGO:0030540140.091
development of primary sexual characteristicsGO:00451371430.091
cellular macromolecule catabolic processGO:00442652060.091
visceral serous pericardium developmentGO:006103220.091
negative regulation of neuron deathGO:1901215980.091
positive regulation of mechanoreceptor differentiationGO:004563310.091
epithelial cell proliferationGO:00506731740.090
apoptotic process involved in mammary gland involutionGO:006005740.090
protein kinase b signalingGO:0043491740.090
renal inner medulla developmentGO:007205330.090
regulation of apoptotic process involved in outflow tract morphogenesisGO:190225620.089
regulation of glial cell differentiationGO:0045685410.089
regulation of actin cytoskeleton organizationGO:0032956840.089
regulation of somitogenesisGO:001480760.089
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.089
nucleoside triphosphate metabolic processGO:00091412300.088
neural crest cell developmentGO:0014032480.088
purine ribonucleotide metabolic processGO:00091502900.088
formation of primary germ layerGO:0001704770.088
neural crest cell migrationGO:0001755320.087
neuron projection extensionGO:1990138640.087
negative regulation of t cell activationGO:0050868650.087
aromatic compound catabolic processGO:00194392860.087
regulation of cytokine productionGO:00018172660.087
signal transduction involved in mitotic g1 dna damage checkpointGO:007243130.086
neuron migrationGO:00017641220.086
chromatin modificationGO:00165681870.086
regulation of chromatin modificationGO:1903308570.085
forebrain generation of neuronsGO:0021872630.085
regulation of nucleotide metabolic processGO:00061401690.085
regulation of morphogenesis of a branching structureGO:0060688530.085
regulation of cell activationGO:00508652890.085
protein ubiquitinationGO:00165671710.084
regulation of muscle cell apoptotic processGO:0010660170.083
methylationGO:00322591340.083
protein processingGO:00164851630.083
tendon formationGO:003599240.083
organic hydroxy compound biosynthetic processGO:1901617770.082
mesenchymal to epithelial transitionGO:0060231120.082
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.082
response to hypoxiaGO:0001666580.082
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.082
organic hydroxy compound metabolic processGO:19016152030.082
hindbrain developmentGO:00309021280.081
regulation of transcription from rna polymerase iii promoterGO:000635920.081
bmp signaling pathwayGO:0030509930.081
peptide transportGO:00158331330.080
ribonucleoside metabolic processGO:00091192450.080
positive regulation of hydrolase activityGO:00513451480.079
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.079
negative regulation of nervous system developmentGO:00519611560.079
purine nucleoside catabolic processGO:00061522050.079
nephron epithelium morphogenesisGO:0072088680.079
regulation of odontogenesisGO:0042481180.078
mesangial cell differentiationGO:007200740.078
negative regulation of cell substrate adhesionGO:0010812160.078
positive regulation of reactive oxygen species metabolic processGO:2000379110.078
thyroid stimulating hormone secreting cell differentiationGO:006012940.077
regulation of gliogenesisGO:0014013500.077
positive regulation of angiogenesisGO:0045766460.077
protein catabolic processGO:00301632210.077
mesodermal cell differentiationGO:0048333220.077
carbon catabolite regulation of transcriptionGO:004599040.076
negative regulation of dna replicationGO:000815640.076
negative regulation of mitotic cell cycleGO:0045930580.076
Human Mouse
negative regulation of cytokine productionGO:0001818840.076
protein autophosphorylationGO:0046777610.076
positive regulation of histone modificationGO:0031058280.076
hematopoietic progenitor cell differentiationGO:00022441430.075
Human
negative regulation of map kinase activityGO:0043407340.075
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.075
regulation of nucleotide catabolic processGO:00308111220.075
nephron developmentGO:00720061090.075
cellular response to lipidGO:00713961450.075
regulation of translationGO:0006417710.075
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.075
carboxylic acid biosynthetic processGO:0046394860.075
negative regulation of cell developmentGO:00107211690.075
extracellular matrix organizationGO:00301981470.075
apoptotic process involved in developmentGO:1902742280.075
regulation of actin filament based processGO:0032970990.074
transdifferentiationGO:006029010.074
cell agingGO:0007569350.074
peptide secretionGO:00027901140.074
positive regulation of cyclic nucleotide biosynthetic processGO:0030804240.074
intracellular protein transportGO:00068862040.074
artery developmentGO:0060840530.073
response to oxidative stressGO:00069791230.073
positive regulation of striated muscle cell apoptotic processGO:001066330.073

Cdkn2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.947
cancerDOID:16200.865
organ system cancerDOID:005068600.865
disease of anatomical entityDOID:700.144
musculoskeletal system diseaseDOID:1700.144
connective tissue diseaseDOID:6500.144
urinary system cancerDOID:399600.086
endocrine gland cancerDOID:17000.079