Mus musculus

0 known processes

Parp8

poly (ADP-ribose) polymerase family, member 8

(Aliases: 2810430O08Rik,D13Ertd275e)

Parp8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of molecular functionGO:00440922580.117
heterocycle catabolic processGO:00467002800.100
hematopoietic progenitor cell differentiationGO:00022441430.099
peptidyl amino acid modificationGO:00181933360.096
regulation of cellular amine metabolic processGO:0033238200.096
negative regulation of phosphate metabolic processGO:00459361840.095
cellular amine metabolic processGO:0044106440.090
organic cyclic compound catabolic processGO:19013612950.087
t cell activationGO:00421102890.085
ribonucleoside metabolic processGO:00091192450.080
cellular amino acid metabolic processGO:00065201030.078
cellular nitrogen compound catabolic processGO:00442702800.076
regulation of nucleotide metabolic processGO:00061401690.073
t cell differentiationGO:00302171740.072
amine metabolic processGO:0009308450.071
leukocyte differentiationGO:00025213420.070
regulation of purine nucleotide metabolic processGO:19005421690.068
regulation of cellular amino acid metabolic processGO:000652150.066
regulation of hydrolase activityGO:00513362460.066
response to lipopolysaccharideGO:00324961280.065
negative regulation of cell proliferationGO:00082852960.064
regulation of apoptotic signaling pathwayGO:20012331970.062
regulation of cellular catabolic processGO:00313292420.061
nucleoside metabolic processGO:00091162460.060
nucleoside phosphate metabolic processGO:00067533380.060
lymphocyte differentiationGO:00300982420.060
regulation of neuron projection developmentGO:00109751690.060
ribose phosphate metabolic processGO:00196932910.059
regulation of cell activationGO:00508652890.058
male gamete generationGO:00482322850.058
regulation of lymphocyte activationGO:00512492400.057
regulation of neuron differentiationGO:00456642810.057
negative regulation of cellular amino acid metabolic processGO:004576300.056
spermatogenesisGO:00072832840.055
purine ribonucleoside triphosphate metabolic processGO:00092052200.053
positive regulation of cell activationGO:00508671580.053
transmembrane transportGO:00550854120.053
regulation of t cell activationGO:00508631700.052
purine ribonucleoside metabolic processGO:00461282410.052
nucleoside triphosphate metabolic processGO:00091412300.052
t cell proliferationGO:00420981200.052
cytoplasmic transportGO:00164822340.052
organonitrogen compound catabolic processGO:19015652640.051
inflammatory responseGO:00069542440.051
negative regulation of protein phosphorylationGO:00019331260.051
nucleotide metabolic processGO:00091173320.050
positive regulation of gtp catabolic processGO:0033126850.049
immune effector processGO:00022523210.049
muscle cell differentiationGO:00426922610.049
purine nucleotide catabolic processGO:00061952110.049
aromatic compound catabolic processGO:00194392860.049
positive regulation of nucleotide catabolic processGO:0030813880.048
chromatin modificationGO:00165681870.046
negative regulation of cellular amine metabolic processGO:003323910.046
cellular ketone metabolic processGO:0042180840.046
positive regulation of nervous system developmentGO:00519622210.046
purine nucleotide metabolic processGO:00061633020.046
regulation of organelle organizationGO:00330432890.045
nucleoside phosphate catabolic processGO:19012922220.045
cellular response to lipopolysaccharideGO:0071222770.045
response to molecule of bacterial originGO:00022371430.044
purine ribonucleoside catabolic processGO:00461302050.044
negative regulation of cellular protein metabolic processGO:00322692470.044
purine ribonucleotide metabolic processGO:00091502900.044
purine containing compound metabolic processGO:00725213110.043
negative regulation of protein modification processGO:00314001630.043
regulation of purine nucleotide catabolic processGO:00331211220.042
ribonucleoside catabolic processGO:00424542060.042
nucleobase containing small molecule metabolic processGO:00550863520.042
regulation of synaptic growth at neuromuscular junctionGO:000858240.042
ribonucleotide catabolic processGO:00092612080.041
purine nucleoside triphosphate catabolic processGO:00091462030.040
lymphocyte proliferationGO:00466511640.040
glycosyl compound catabolic processGO:19016582060.039
purine nucleoside metabolic processGO:00422782410.039
ribonucleotide metabolic processGO:00092592910.038
leukocyte proliferationGO:00706611720.038
positive regulation of programmed cell deathGO:00430682180.038
purine containing compound catabolic processGO:00725232130.037
positive regulation of cellular amino acid metabolic processGO:004576430.037
purine nucleoside triphosphate metabolic processGO:00091442260.037
regulation of nucleoside metabolic processGO:00091181300.037
regulation of cellular ketone metabolic processGO:0010565660.036
ribonucleoside triphosphate metabolic processGO:00091992200.036
cellular response to molecule of bacterial originGO:0071219830.036
protein ubiquitinationGO:00165671710.035
nucleoside catabolic processGO:00091642060.035
regulation of cytokine productionGO:00018172660.035
positive regulation of cell deathGO:00109422240.035
peptidyl tyrosine phosphorylationGO:00181081430.035
positive regulation of cellular amine metabolic processGO:003324050.035
muscle tissue developmentGO:00605373080.035
regulation of mapk cascadeGO:00434082480.035
gtp metabolic processGO:00460391440.034
ribonucleoside triphosphate catabolic processGO:00092031990.034
cytokine productionGO:00018163190.033
cation transportGO:00068123990.033
regulation of protein complex assemblyGO:0043254830.033
compound eye developmentGO:004874910.033
peptidyl serine modificationGO:0018209830.033
positive regulation of gtpase activityGO:0043547850.032
positive regulation of hydrolase activityGO:00513451480.032
positive regulation of apoptotic signaling pathwayGO:2001235950.032
regulation of adaptive immune responseGO:0002819900.032
cellular protein complex assemblyGO:00436231160.032
leukocyte mediated immunityGO:00024431740.032
cellular response to cytokine stimulusGO:00713451890.032
positive regulation of lymphocyte activationGO:00512511400.032
nucleotide catabolic processGO:00091662170.031
negative regulation of protein metabolic processGO:00512482820.031
protein modification by small protein conjugation or removalGO:00706472070.031
adaptive immune responseGO:00022501550.031
antigen receptor mediated signaling pathwayGO:0050851640.030
apoptotic signaling pathwayGO:00971903060.030
multicellular organism growthGO:00352641610.030
regulation of gtp catabolic processGO:00331241130.030
regulation of protein kinase activityGO:00458592320.030
cation transmembrane transportGO:00986552660.030
guanosine containing compound catabolic processGO:19010691440.029
sensory organ morphogenesisGO:00905962420.029
negative regulation of immune system processGO:00026832090.029
muscle system processGO:00030121410.029
positive regulation of apoptotic processGO:00430652170.029
response to organonitrogen compoundGO:00102432460.029
purine nucleoside catabolic processGO:00061522050.029
chromatin organizationGO:00063252060.028
positive regulation of protein phosphorylationGO:00019342420.028
protein modification by small protein conjugationGO:00324461870.028
purine ribonucleoside triphosphate catabolic processGO:00092071990.028
alpha beta t cell activationGO:0046631910.028
carbohydrate derivative catabolic processGO:19011362310.028
negative regulation of phosphorylationGO:00423261660.028
gtp catabolic processGO:00061841430.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.027
rho protein signal transductionGO:0007266320.027
regulation of kinase activityGO:00435492490.027
regulation of defense responseGO:00313472330.027
regulation of anatomical structure sizeGO:00900661780.027
cellular response to biotic stimulusGO:0071216920.026
blood vessel morphogenesisGO:00485142850.026
glycosyl compound metabolic processGO:19016572460.026
histone modificationGO:00165701590.026
nitrogen compound transportGO:00717052710.026
cellular response to organonitrogen compoundGO:00714171450.026
positive regulation of protein modification processGO:00314012990.025
peptidyl tyrosine modificationGO:00182121450.025
g protein coupled receptor signaling pathwayGO:00071862430.025
mapk cascadeGO:00001652810.025
negative regulation of intracellular signal transductionGO:19025321670.025
nucleoside triphosphate catabolic processGO:00091432050.025
muscle contractionGO:00069361010.025
intracellular protein transportGO:00068862040.024
negative regulation of nervous system developmentGO:00519611560.024
positive regulation of nucleoside metabolic processGO:0045979910.024
fat cell differentiationGO:00454441600.024
positive regulation of growthGO:00459271040.024
maintenance of locationGO:0051235890.024
gland developmentGO:00487323300.024
regulation of t cell proliferationGO:0042129920.024
ion transmembrane transportGO:00342203610.023
regulation of response to woundingGO:19030341890.023
positive regulation of cell developmentGO:00107202370.023
digestive system developmentGO:00551232000.023
regulation of lymphocyte proliferationGO:00506701170.023
chemotaxisGO:00069352470.023
morphogenesis of embryonic epitheliumGO:00163311590.023
macromolecule catabolic processGO:00090572810.023
regulation of nucleotide catabolic processGO:00308111220.023
regulation of secretion by cellGO:19035302490.023
regulation of leukocyte mediated immunityGO:00027031040.022
covalent chromatin modificationGO:00165691630.022
membrane organizationGO:00610242450.022
carbohydrate metabolic processGO:00059752300.022
purine ribonucleotide catabolic processGO:00091542080.022
dna metabolic processGO:00062593030.022
positive regulation of secretionGO:00510471300.022
epithelial tube morphogenesisGO:00605623030.022
negative regulation of cellular component organizationGO:00511291940.022
angiogenesisGO:00015252010.022
nuclear transportGO:00511691390.022
cell growthGO:00160491300.022
dendrite developmentGO:00163581150.022
striated muscle tissue developmentGO:00147062930.022
small gtpase mediated signal transductionGO:0007264970.021
embryonic organ morphogenesisGO:00485622760.021
immune response regulating signaling pathwayGO:00027641250.021
carbohydrate derivative biosynthetic processGO:19011371830.021
regulation of cellular component biogenesisGO:00440871810.021
ras protein signal transductionGO:0007265770.021
regulation of secretionGO:00510462740.021
peptidyl serine phosphorylationGO:0018105740.021
negative regulation of t cell activationGO:0050868650.021
regulation of cytoskeleton organizationGO:00514931220.021
regulation of protein localizationGO:00328802310.020
protein localization to organelleGO:00333651850.020
regulation of inflammatory responseGO:00507271470.020
reactive oxygen species metabolic processGO:0072593840.020
negative regulation of lymphocyte activationGO:0051250910.020
digestive tract developmentGO:00485651900.020
regulation of cell adhesionGO:00301551540.020
cardiac muscle contractionGO:0060048320.020
positive regulation of lymphocyte proliferationGO:0050671700.020
tube formationGO:00351481400.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
protein catabolic processGO:00301632210.020
regulation of lymphocyte differentiationGO:00456191070.020
regulation of intracellular protein transportGO:0033157820.020
positive regulation of cytokine productionGO:00018191740.020
alpha beta t cell differentiationGO:0046632690.020
cell type specific apoptotic processGO:00972852680.020
cell activation involved in immune responseGO:00022631260.020
immune response regulating cell surface receptor signaling pathwayGO:0002768800.020
mrna metabolic processGO:0016071840.020
cellular response to lipidGO:00713961450.020
b cell proliferationGO:0042100530.020
positive regulation of nucleotide metabolic processGO:00459811140.019
response to peptide hormoneGO:00434341270.019
regulation of sequence specific dna binding transcription factor activityGO:00510901060.019
embryonic epithelial tube formationGO:00018381300.019
regulation of cell projection organizationGO:00313442060.019
response to growth factorGO:00708481980.019
innate immune responseGO:00450871570.019
neuron apoptotic processGO:00514021420.019
neural tube developmentGO:00219151600.019
regulation of leukocyte differentiationGO:19021051590.019
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.019
muscle adaptationGO:0043500390.019
negative regulation of cell developmentGO:00107211690.019
protein polymerizationGO:0051258570.019
circulatory system processGO:00030131970.019
positive regulation of neuron differentiationGO:00456661410.019
regulation of lymphocyte mediated immunityGO:0002706840.019
positive regulation of ras gtpase activityGO:0032320650.019
cellular response to hormone stimulusGO:00328701500.018
positive regulation of leukocyte proliferationGO:0070665730.018
gonad developmentGO:00084061410.018
organophosphate catabolic processGO:00464342320.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
regulation of vesicle mediated transportGO:00606271390.018
vesicle fusionGO:0006906160.018
camera type eye developmentGO:00430102660.018
retrograde transport endosome to golgiGO:004214720.018
cellular macromolecule catabolic processGO:00442652060.018
protein processingGO:00164851630.018
neuron deathGO:00709971540.018
synaptic transmissionGO:00072683290.018
immune response activating signal transductionGO:00027571160.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
positive regulation of cellular catabolic processGO:00313311480.018
neural tube formationGO:00018411080.018
blood circulationGO:00080151950.018
oxidation reduction processGO:00551143420.017
inorganic cation transmembrane transportGO:00986622070.017
regulation of mrna processingGO:0050684410.017
skeletal system developmentGO:00015013560.017
cell adhesionGO:00071553290.017
sequestering of metal ionGO:0051238190.017
negative regulation of phospholipase activityGO:001051940.017
axon target recognitionGO:000741240.017
regulation of antigen receptor mediated signaling pathwayGO:0050854290.017
cellular protein catabolic processGO:00442571550.017
regulation of cell growthGO:0001558910.017
regulation of protein transportGO:00512231630.017
epithelial tube formationGO:00721751300.017
microtubule based processGO:00070172360.017
actin cytoskeleton organizationGO:00300362200.017
neural tube closureGO:0001843900.017
cytokine biosynthetic processGO:0042089680.017
activation of immune responseGO:00022531380.017
regulation of hormone levelsGO:00108172110.017
protein targetingGO:00066051430.017
glycoprotein metabolic processGO:00091001160.017
multicellular organismal signalingGO:0035637910.016
regulation of ras protein signal transductionGO:00465781140.016
negative regulation of camp mediated signalingGO:004395130.016
positive regulation of defense responseGO:00313491240.016
regulation of transferase activityGO:00513382630.016
regulation of t cell differentiationGO:0045580830.016
regulation of ras gtpase activityGO:0032318880.016
regulation of cytoplasmic transportGO:19036491120.016
lymphocyte mediated immunityGO:00024491390.016
negative regulation of neuron differentiationGO:00456651010.016
negative regulation of cytokine productionGO:0001818840.016
dna recombinationGO:0006310920.016
methylationGO:00322591340.016
myeloid cell differentiationGO:00300992330.015
actin filament organizationGO:00070151130.015
negative regulation of phosphorus metabolic processGO:00105631840.015
defense response to other organismGO:00985421970.015
regulation of establishment of protein localizationGO:00702011810.015
negative regulation of hydrolase activityGO:0051346710.015
regulation of adrenergic receptor signaling pathwayGO:007187740.015
transforming growth factor beta receptor signaling pathwayGO:0007179710.015
protein alkylationGO:0008213810.015
positive regulation of secretion by cellGO:19035321140.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
response to peptideGO:19016521360.015
primary neural tube formationGO:0014020950.015
lymphocyte activation involved in immune responseGO:0002285930.015
regulation of neuron apoptotic processGO:00435231220.015
actin polymerization or depolymerizationGO:0008154540.015
ossificationGO:00015032160.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
nucleocytoplasmic transportGO:00069131390.015
negative regulation of cell activationGO:00508661110.015
forebrain developmentGO:00309003020.014
immune response activating cell surface receptor signaling pathwayGO:0002429720.014
homeostasis of number of cellsGO:00488722100.014
modification dependent macromolecule catabolic processGO:00436321330.014
positive regulation of t cell activationGO:00508701010.014
heart processGO:0003015940.014
positive regulation of immune effector processGO:00026991070.014
cellular lipid metabolic processGO:00442553230.014
positive regulation of proteolysisGO:0045862850.014
response to organic cyclic compoundGO:00140701980.014
negative regulation of synapse assemblyGO:005196430.014
cellular homeostasisGO:00197252400.014
cd4 positive alpha beta t cell activationGO:0035710450.014
hexose metabolic processGO:0019318980.014
t cell activation involved in immune responseGO:0002286430.014
rhythmic processGO:00485111740.014
endocytosisGO:00068971680.014
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.014
regulation of peptidyl tyrosine phosphorylationGO:0050730930.014
lung developmentGO:00303241640.014
organelle localizationGO:00516401790.014
regulation of leukocyte proliferationGO:00706631210.014
cytokine mediated signaling pathwayGO:00192211150.014
renal system developmentGO:00720012250.014
negative regulation of kinase activityGO:0033673810.013
regulation of protein serine threonine kinase activityGO:00719001570.013
macromolecule methylationGO:00434141200.013
respiratory tube developmentGO:00303231670.013
positive regulation of cell projection organizationGO:0031346950.013
muscle cell developmentGO:00550011330.013
multi multicellular organism processGO:00447061090.013
positive regulation of protein transportGO:0051222930.013
midgut developmentGO:000749440.013
anion transportGO:00068201770.013
membrane fusionGO:0061025380.013
axonogenesisGO:00074092740.013
protein autophosphorylationGO:0046777610.013
mrna processingGO:0006397630.013
positive regulation of neuron projection developmentGO:0010976790.013
rna processingGO:00063961050.013
developmental growth involved in morphogenesisGO:00605601380.013
organic anion transportGO:00157111370.013
amide transportGO:00428861380.013
rna splicing via transesterification reactionsGO:0000375430.013
development of primary sexual characteristicsGO:00451371430.013
response to transforming growth factor betaGO:0071559880.013
regulation of bindingGO:00510981110.013
lipid localizationGO:00108761260.013
protein secretionGO:00093061110.013
regulation of rho gtpase activityGO:0032319580.013
reactive oxygen species biosynthetic processGO:190340980.013
positive regulation of reactive oxygen species metabolic processGO:2000379110.013
reactive nitrogen species metabolic processGO:200105700.013
peptidyl threonine phosphorylationGO:0018107310.013
t cell mediated immunityGO:0002456500.013
muscle fiber developmentGO:0048747760.012
exocytosisGO:00068871210.012
defense response to virusGO:0051607680.012
positive regulation of leukocyte mediated immunityGO:0002705700.012
cytokine metabolic processGO:0042107710.012
regulation of mrna splicing via spliceosomeGO:0048024320.012
wnt signaling pathwayGO:00160551880.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.012
lateral inhibitionGO:004633110.012
regulation of cellular response to stressGO:00801351590.012
developmental maturationGO:00217001930.012
negative regulation of cell adhesionGO:0007162450.012
response to oxidative stressGO:00069791230.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
regulation of cell migrationGO:00303342190.012
skeletal muscle organ developmentGO:00605381630.012
cd4 positive alpha beta t cell differentiationGO:0043367410.012
t cell receptor signaling pathwayGO:0050852460.012
sequestering of calcium ionGO:0051208180.012
striated muscle cell developmentGO:00550021250.012
heart contractionGO:0060047930.012
organelle assemblyGO:00709251770.012
respiratory system developmentGO:00605411900.012
response to nutrient levelsGO:00316671090.012
urogenital system developmentGO:00016552610.012
regulation of peptidase activityGO:0052547960.012
carbohydrate homeostasisGO:00335001280.012
t cell differentiation in thymusGO:0033077770.012
leukocyte mediated cytotoxicityGO:0001909620.012
peptide secretionGO:00027901140.012
organic hydroxy compound metabolic processGO:19016152030.012
regulation of intracellular transportGO:00323861590.012
regulation of ion transportGO:00432692150.012
regulation of nucleocytoplasmic transportGO:0046822730.011
cellular chemical homeostasisGO:00550822150.011
glucose metabolic processGO:0006006920.011
negative regulation of mapk cascadeGO:0043409650.011
regulation of cell substrate adhesionGO:0010810730.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
inorganic ion transmembrane transportGO:00986602340.011
regulation of cell sizeGO:0008361720.011
leukocyte activation involved in immune responseGO:00023661260.011
guanosine containing compound metabolic processGO:19010681440.011
regulation of protein localization to nucleusGO:1900180600.011
positive regulation of wnt signaling pathwayGO:0030177450.011
organonitrogen compound biosynthetic processGO:19015661920.011
b cell activationGO:00421131610.011
response to extracellular stimulusGO:00099911270.011
apoptotic mitochondrial changesGO:0008637480.011
connective tissue developmentGO:00614481790.011
protein localization to nucleusGO:00345041210.011
canonical wnt signaling pathwayGO:00600701300.011
posttranscriptional regulation of gene expressionGO:00106081550.011
monosaccharide transportGO:0015749580.011
negative regulation of protein processingGO:0010955790.011
relaxation of muscleGO:0090075180.011
regulation of insulin receptor signaling pathwayGO:0046626210.011
regulation of protein processingGO:0070613960.011
anatomical structure homeostasisGO:00602491450.011
modification dependent protein catabolic processGO:00199411330.011
peripheral nervous system neuron axonogenesisGO:004893630.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
negative regulation of growthGO:0045926990.011
stem cell developmentGO:00488642190.011
negative regulation of transferase activityGO:0051348850.011
regulation of cell cycleGO:00517262810.011
meiotic nuclear divisionGO:00071261150.011
intracellular receptor signaling pathwayGO:0030522740.010
regulation of protein bindingGO:0043393600.010
myeloid leukocyte differentiationGO:00025731190.010
myotube differentiationGO:00149021050.010
peptide hormone secretionGO:00300721090.010
positive regulation of organelle organizationGO:00106381280.010
protein acylationGO:0043543640.010
organelle fusionGO:0048284280.010
regulation of system processGO:00440572000.010
regulation of wnt signaling pathwayGO:00301111230.010
ubiquitin dependent protein catabolic processGO:00065111290.010
cellular response to peptideGO:1901653920.010
skeletal muscle cell differentiationGO:0035914660.010
calcium ion transmembrane transportGO:0070588850.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
male sex differentiationGO:00466611090.010
regulation of blood circulationGO:1903522930.010
skeletal system morphogenesisGO:00487052030.010
microtubule cytoskeleton organizationGO:00002261570.010
regulation of mrna metabolic processGO:1903311430.010
b cell differentiationGO:0030183780.010
positive regulation of t cell proliferationGO:0042102520.010
mitochondrion distributionGO:004831140.010
tissue remodelingGO:00487711020.010

Parp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.025
organ system cancerDOID:005068600.019
cancerDOID:16200.019
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018