Mus musculus

0 known processes

Parp6

poly (ADP-ribose) polymerase family, member 6

(Aliases: PARP-6,3110038K10Rik,2310028P13Rik,1700119G14Rik,C030013N01Rik)

Parp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565660.111
peptidyl amino acid modificationGO:00181933360.102
organic cyclic compound catabolic processGO:19013612950.078
protein ubiquitinationGO:00165671710.076
regulation of nucleoside metabolic processGO:00091181300.073
gtp metabolic processGO:00460391440.068
purine ribonucleotide metabolic processGO:00091502900.066
regulation of cellular amino acid metabolic processGO:000652150.065
cellular response to dna damage stimulusGO:00069742070.064
nucleoside phosphate metabolic processGO:00067533380.063
glycosyl compound catabolic processGO:19016582060.061
heterocycle catabolic processGO:00467002800.060
purine containing compound catabolic processGO:00725232130.057
purine nucleoside triphosphate metabolic processGO:00091442260.056
aromatic compound catabolic processGO:00194392860.055
protein modification by small protein conjugation or removalGO:00706472070.055
positive regulation of cellular catabolic processGO:00313311480.055
male gamete generationGO:00482322850.054
cellular amino acid metabolic processGO:00065201030.052
macromolecule catabolic processGO:00090572810.051
negative regulation of phosphorus metabolic processGO:00105631840.051
axonogenesisGO:00074092740.051
negative regulation of cellular protein metabolic processGO:00322692470.051
carbohydrate derivative catabolic processGO:19011362310.050
purine ribonucleotide catabolic processGO:00091542080.050
nucleoside metabolic processGO:00091162460.049
regulation of nucleotide metabolic processGO:00061401690.048
purine nucleotide metabolic processGO:00061633020.048
histone modificationGO:00165701590.047
cellular nitrogen compound catabolic processGO:00442702800.047
negative regulation of nervous system developmentGO:00519611560.046
purine ribonucleoside triphosphate metabolic processGO:00092052200.046
organonitrogen compound catabolic processGO:19015652640.045
carbohydrate metabolic processGO:00059752300.045
ribonucleotide metabolic processGO:00092592910.044
organophosphate catabolic processGO:00464342320.044
ribonucleoside triphosphate metabolic processGO:00091992200.044
regulation of synaptic growth at neuromuscular junctionGO:000858240.043
negative regulation of cellular component organizationGO:00511291940.043
negative regulation of cellular amine metabolic processGO:003323910.042
glycosyl compound metabolic processGO:19016572460.041
intracellular protein transportGO:00068862040.041
purine nucleotide catabolic processGO:00061952110.041
negative regulation of protein phosphorylationGO:00019331260.041
blood vessel morphogenesisGO:00485142850.041
nucleoside phosphate catabolic processGO:19012922220.041
negative regulation of protein metabolic processGO:00512482820.041
purine ribonucleoside catabolic processGO:00461302050.041
ras protein signal transductionGO:0007265770.040
protein modification by small protein conjugationGO:00324461870.040
positive regulation of gtp catabolic processGO:0033126850.040
regulation of kinase activityGO:00435492490.039
positive regulation of gtpase activityGO:0043547850.039
regulation of purine nucleotide metabolic processGO:19005421690.039
chromatin modificationGO:00165681870.039
regulation of neuron differentiationGO:00456642810.038
nitrogen compound transportGO:00717052710.038
nucleoside catabolic processGO:00091642060.038
cellular amine metabolic processGO:0044106440.038
negative regulation of protein modification processGO:00314001630.038
positive regulation of cell deathGO:00109422240.038
regulation of cellular catabolic processGO:00313292420.038
cellular ketone metabolic processGO:0042180840.038
organelle localizationGO:00516401790.038
cellular lipid metabolic processGO:00442553230.037
protein catabolic processGO:00301632210.037
regulation of cell sizeGO:0008361720.037
regulation of purine nucleotide catabolic processGO:00331211220.037
regulation of organelle organizationGO:00330432890.037
regulation of nucleotide catabolic processGO:00308111220.037
guanosine containing compound catabolic processGO:19010691440.037
chromatin organizationGO:00063252060.037
regulation of mapk cascadeGO:00434082480.037
small gtpase mediated signal transductionGO:0007264970.036
positive regulation of nucleotide catabolic processGO:0030813880.036
negative regulation of phosphorylationGO:00423261660.036
regulation of intracellular transportGO:00323861590.036
negative regulation of cell developmentGO:00107211690.035
purine nucleoside metabolic processGO:00422782410.035
regulation of anatomical structure sizeGO:00900661780.035
transmembrane transportGO:00550854120.035
negative regulation of phosphate metabolic processGO:00459361840.035
amine metabolic processGO:0009308450.035
nucleoside triphosphate catabolic processGO:00091432050.035
nucleobase containing small molecule metabolic processGO:00550863520.034
purine containing compound metabolic processGO:00725213110.034
ribonucleoside triphosphate catabolic processGO:00092031990.034
regulation of gtp catabolic processGO:00331241130.034
purine nucleoside catabolic processGO:00061522050.034
regulation of secretionGO:00510462740.034
purine ribonucleoside metabolic processGO:00461282410.033
negative regulation of molecular functionGO:00440922580.033
positive regulation of nucleotide metabolic processGO:00459811140.033
positive regulation of nucleoside metabolic processGO:0045979910.033
protein localization to membraneGO:00726571080.033
microtubule based processGO:00070172360.033
homeostasis of number of cellsGO:00488722100.032
neuron projection extensionGO:1990138640.032
nucleotide catabolic processGO:00091662170.032
regulation of cellular amine metabolic processGO:0033238200.032
dna metabolic processGO:00062593030.032
cytoplasmic transportGO:00164822340.032
endomembrane system organizationGO:00102561470.032
ribonucleotide catabolic processGO:00092612080.032
mapk cascadeGO:00001652810.032
positive regulation of purine nucleotide catabolic processGO:0033123880.031
germ cell developmentGO:00072811850.031
cellular macromolecule catabolic processGO:00442652060.031
establishment of organelle localizationGO:00516561220.031
ribonucleoside metabolic processGO:00091192450.031
covalent chromatin modificationGO:00165691630.030
protein localization to organelleGO:00333651850.030
regulation of hydrolase activityGO:00513362460.030
apoptotic signaling pathwayGO:00971903060.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.030
regulation of membrane potentialGO:00423911920.030
cell growthGO:00160491300.029
gtp catabolic processGO:00061841430.029
purine nucleoside triphosphate catabolic processGO:00091462030.029
regulation of cellular component biogenesisGO:00440871810.029
ribose phosphate metabolic processGO:00196932910.029
mitochondrion organizationGO:00070051340.029
nucleotide metabolic processGO:00091173320.029
nucleoside triphosphate metabolic processGO:00091412300.029
regulation of ras gtpase activityGO:0032318880.028
establishment or maintenance of cytoskeleton polarityGO:003095220.028
regulation of neuron projection developmentGO:00109751690.028
regionalizationGO:00030023370.028
response to organonitrogen compoundGO:00102432460.028
regulation of homeostatic processGO:00328441820.028
regulation of cell projection organizationGO:00313442060.028
regulation of protein kinase activityGO:00458592320.028
peptidyl serine modificationGO:0018209830.028
regulation of ion transportGO:00432692150.027
regulation of cell morphogenesis involved in differentiationGO:00107691510.027
ubiquitin dependent protein catabolic processGO:00065111290.027
negative regulation of cell proliferationGO:00082852960.027
tube formationGO:00351481400.027
microtubule cytoskeleton organizationGO:00002261570.027
positive regulation of ras gtpase activityGO:0032320650.027
positive regulation of purine nucleotide metabolic processGO:19005441140.026
ribonucleoside catabolic processGO:00424542060.026
membrane organizationGO:00610242450.026
positive regulation of hydrolase activityGO:00513451480.025
skeletal system developmentGO:00015013560.025
autophagyGO:0006914450.025
engulfment of apoptotic cellGO:004365230.025
positive regulation of programmed cell deathGO:00430682180.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
response to peptideGO:19016521360.025
positive regulation of cellular amine metabolic processGO:003324050.025
posttranscriptional regulation of gene expressionGO:00106081550.025
spermatogenesisGO:00072832840.025
developmental cell growthGO:0048588840.025
multicellular organism growthGO:00352641610.024
regulation of transferase activityGO:00513382630.024
regulation of reactive oxygen species metabolic processGO:2000377400.024
regulation of protein localizationGO:00328802310.024
positive regulation of organelle organizationGO:00106381280.024
establishment or maintenance of cell polarityGO:0007163860.024
neural tube developmentGO:00219151600.024
guanosine containing compound metabolic processGO:19010681440.024
regulation of vasculature developmentGO:1901342880.024
peptidyl serine phosphorylationGO:0018105740.024
positive regulation of cellular component biogenesisGO:0044089940.023
translationGO:0006412930.023
response to lipopolysaccharideGO:00324961280.023
positive regulation of cell developmentGO:00107202370.023
epithelial tube morphogenesisGO:00605623030.023
negative regulation of synapse assemblyGO:005196430.022
negative regulation of growthGO:0045926990.022
regulation of vesicle mediated transportGO:00606271390.022
actin cytoskeleton organizationGO:00300362200.022
peptidyl tyrosine phosphorylationGO:00181081430.022
developmental growth involved in morphogenesisGO:00605601380.022
proteolysis involved in cellular protein catabolic processGO:00516031470.022
digestive system developmentGO:00551232000.022
regulation of intracellular protein transportGO:0033157820.022
regulation of ral gtpase activityGO:003231540.022
organelle assemblyGO:00709251770.022
negative regulation of cellular amino acid metabolic processGO:004576300.021
regulation of apoptotic signaling pathwayGO:20012331970.021
leukocyte differentiationGO:00025213420.021
neuron apoptotic processGO:00514021420.021
positive regulation of apoptotic processGO:00430652170.020
modification dependent protein catabolic processGO:00199411330.020
response to growth factorGO:00708481980.020
regulation of protein serine threonine kinase activityGO:00719001570.020
morphogenesis of embryonic epitheliumGO:00163311590.020
wnt signaling pathwayGO:00160551880.020
rna processingGO:00063961050.020
neuron projection guidanceGO:00974851410.020
myeloid cell homeostasisGO:00022621140.020
establishment of protein localization to membraneGO:0090150540.020
cellular response to organonitrogen compoundGO:00714171450.020
regulation of protein transportGO:00512231630.020
negative regulation of intracellular signal transductionGO:19025321670.020
angiogenesisGO:00015252010.019
regulation of proteolysisGO:00301621640.019
transcription from rna polymerase iii promoterGO:000638330.019
endocytosisGO:00068971680.019
response to peptide hormoneGO:00434341270.019
positive regulation of protein phosphorylationGO:00019342420.019
positive regulation of intracellular protein transportGO:0090316420.019
cellular response to cytokine stimulusGO:00713451890.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
regulation of ras protein signal transductionGO:00465781140.019
forebrain developmentGO:00309003020.019
cellular response to peptideGO:1901653920.019
regulation of cytoskeleton organizationGO:00514931220.019
immune effector processGO:00022523210.019
regulation of cellular component sizeGO:00325351210.019
regulation of system processGO:00440572000.018
mitochondrion transport along microtubuleGO:004749730.018
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.018
asymmetric stem cell divisionGO:009872230.018
organelle fissionGO:00482851700.018
response to insulinGO:00328681000.018
cellular response to growth factor stimulusGO:00713631970.018
inorganic ion transmembrane transportGO:00986602340.018
cellular response to lipopolysaccharideGO:0071222770.018
cation transportGO:00068123990.018
nucleocytoplasmic transportGO:00069131390.018
chemotaxisGO:00069352470.018
positive regulation of protein modification processGO:00314012990.018
regulation of voltage gated calcium channel activityGO:190138540.018
regulation of secretion by cellGO:19035302490.018
mitotic cell cycleGO:00002781950.018
cytokine productionGO:00018163190.018
cellular homeostasisGO:00197252400.018
response to molecule of bacterial originGO:00022371430.018
maintenance of locationGO:0051235890.018
retrograde transport endosome to golgiGO:004214720.018
peptidyl tyrosine modificationGO:00182121450.018
negative regulation of transferase activityGO:0051348850.018
skin developmentGO:00435882200.017
nuclear transportGO:00511691390.017
development of primary sexual characteristicsGO:00451371430.017
regulation of sequence specific dna binding transcription factor activityGO:00510901060.017
embryonic epithelial tube formationGO:00018381300.017
telencephalon developmentGO:00215371860.017
ossificationGO:00015032160.017
negative regulation of kinase activityGO:0033673810.017
primary neural tube formationGO:0014020950.017
regulation of axon extensionGO:0030516430.017
g protein coupled receptor signaling pathwayGO:00071862430.017
regulation of establishment of protein localizationGO:00702011810.017
cognitionGO:00508901490.017
microtubule based movementGO:0007018840.017
regulation of map kinase activityGO:00434051200.017
oxidation reduction processGO:00551143420.017
regulation of wnt signaling pathwayGO:00301111230.017
fat cell differentiationGO:00454441600.017
synaptic transmissionGO:00072683290.017
central nervous system neuron differentiationGO:00219531620.017
cellular response to hormone stimulusGO:00328701500.017
positive regulation of intracellular transportGO:0032388700.017
cellular response to biotic stimulusGO:0071216920.017
regulation of transmembrane transportGO:00347621280.016
methylationGO:00322591340.016
meiosis iGO:0007127600.016
developmental maturationGO:00217001930.016
positive regulation of proteolysisGO:0045862850.016
meiotic cell cycleGO:00513211220.016
axon guidanceGO:00074111410.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
amide transportGO:00428861380.016
cell type specific apoptotic processGO:00972852680.016
respiratory tube developmentGO:00303231670.016
cellular protein catabolic processGO:00442571550.016
regulation of cytokine productionGO:00018172660.016
positive regulation of transferase activityGO:00513471670.016
protein maturationGO:00516041760.016
regulation of ion transmembrane transportGO:00347651190.016
protein localization to plasma membraneGO:0072659570.016
protein acylationGO:0043543640.016
peptidyl threonine modificationGO:0018210310.016
monosaccharide metabolic processGO:00059961060.015
cellular response to insulin stimulusGO:0032869780.015
mrna metabolic processGO:0016071840.015
multicellular organismal signalingGO:0035637910.015
cellular protein complex assemblyGO:00436231160.015
proteasomal protein catabolic processGO:0010498980.015
organic hydroxy compound metabolic processGO:19016152030.015
nuclear divisionGO:00002801580.015
positive regulation of kinase activityGO:00336741550.015
ion transmembrane transportGO:00342203610.015
rna splicingGO:0008380540.015
ral protein signal transductionGO:003248420.015
protein targetingGO:00066051430.015
regulation of cell growthGO:0001558910.015
regulation of bindingGO:00510981110.015
regulation of protein complex assemblyGO:0043254830.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
phospholipid metabolic processGO:0006644870.015
p38mapk cascadeGO:003806640.015
modification dependent macromolecule catabolic processGO:00436321330.015
endodermal cell fate specificationGO:000171440.014
regulation of cell cycleGO:00517262810.014
t cell activationGO:00421102890.014
regulation of hormone levelsGO:00108172110.014
transmission of nerve impulseGO:0019226760.014
cilium morphogenesisGO:00602711020.014
negative regulation of wnt signaling pathwayGO:0030178730.014
dephosphorylationGO:00163111290.014
inorganic cation transmembrane transportGO:00986622070.014
glucose homeostasisGO:00425931280.014
regulation of extent of cell growthGO:0061387520.014
carbohydrate derivative biosynthetic processGO:19011371830.014
regulation of insulin receptor signaling pathwayGO:0046626210.014
epidermis developmentGO:00085441870.014
leukocyte homeostasisGO:0001776790.014
microtubule based transportGO:0010970500.014
neural tube formationGO:00018411080.014
lymphocyte differentiationGO:00300982420.014
negative regulation of immune system processGO:00026832090.014
lipid localizationGO:00108761260.014
cellular response to peptide hormone stimulusGO:0071375920.014
regulation of ral protein signal transductionGO:003248540.014
t cell differentiationGO:00302171740.013
learning or memoryGO:00076111480.013
skeletal muscle organ developmentGO:00605381630.013
anatomical structure homeostasisGO:00602491450.013
cellular response to molecule of bacterial originGO:0071219830.013
reactive oxygen species metabolic processGO:0072593840.013
regulation of translationGO:0006417710.013
peptidyl lysine modificationGO:0018205770.013
tube closureGO:0060606910.013
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.013
regulation of angiogenesisGO:0045765810.013
epithelial cell proliferationGO:00506731740.013
cellular component assembly involved in morphogenesisGO:00109271390.013
hexose metabolic processGO:0019318980.013
plasma membrane organizationGO:0007009900.013
intracellular mrna localizationGO:000829840.013
gliogenesisGO:00420631410.013
camera type eye developmentGO:00430102660.013
positive regulation of protein transportGO:0051222930.013
cell fate commitmentGO:00451652100.013
lipid transportGO:0006869980.013
positive regulation of neuron differentiationGO:00456661410.013
regulation of metal ion transportGO:00109591060.013
synaptic vesicle transportGO:0048489570.013
inflammatory responseGO:00069542440.013
blood circulationGO:00080151950.013
hindbrain developmentGO:00309021280.013
cellular response to lipidGO:00713961450.013
muscle cell differentiationGO:00426922610.013
regulation of cell migrationGO:00303342190.013
response to acid chemicalGO:00011011110.013
protein import into nucleusGO:0006606950.013
meiotic nuclear divisionGO:00071261150.012
meiotic cell cycle processGO:1903046770.012
establishment of protein localization to organelleGO:00725941180.012
skeletal system morphogenesisGO:00487052030.012
rho protein signal transductionGO:0007266320.012
carbohydrate transportGO:0008643620.012
cytokine biosynthetic processGO:0042089680.012
positive regulation of nervous system developmentGO:00519622210.012
sensory organ morphogenesisGO:00905962420.012
regulation of high voltage gated calcium channel activityGO:190184120.012
regulation of lymphocyte activationGO:00512492400.012
cation homeostasisGO:00550802120.012
learningGO:0007612980.012
regulation of neuron deathGO:19012141340.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
anion transportGO:00068201770.012
muscle adaptationGO:0043500390.012
vesicle localizationGO:0051648860.012
sequestering of calcium ionGO:0051208180.012
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.012
negative regulation of cell projection organizationGO:0031345560.012
lateral inhibitionGO:004633110.012
negative regulation of organelle organizationGO:0010639900.012
organonitrogen compound biosynthetic processGO:19015661920.012
action potentialGO:0001508780.012
carbohydrate homeostasisGO:00335001280.012
regulation of cell migration involved in sprouting angiogenesisGO:009004940.012
regulation of leukocyte differentiationGO:19021051590.011
peptide hormone secretionGO:00300721090.011
negative regulation of cell growthGO:0030308440.011
gonad developmentGO:00084061410.011
regulation of carbohydrate metabolic processGO:0006109750.011
positive regulation of cell projection organizationGO:0031346950.011
sequestering of metal ionGO:0051238190.011
response to inorganic substanceGO:0010035960.011
hormone secretionGO:00468791280.011
retina development in camera type eyeGO:00600411190.011
negative regulation of multi organism processGO:0043901680.011
glucose metabolic processGO:0006006920.011
divalent inorganic cation transportGO:00725111780.011
canonical wnt signaling pathwayGO:00600701300.011
protein polymerizationGO:0051258570.011
response to organic cyclic compoundGO:00140701980.011
localization within membraneGO:005166840.011
synapse organizationGO:00508081250.011
positive regulation of secretion by cellGO:19035321140.011
peptidyl threonine phosphorylationGO:0018107310.011
synaptic vesicle localizationGO:0097479590.011
metencephalon developmentGO:0022037890.011
regulation of hormone secretionGO:0046883880.011
cation transmembrane transportGO:00986552660.011
negative regulation of mapk cascadeGO:0043409650.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
vesicle organizationGO:0016050600.011
dna repairGO:00062811070.011
regulation of actin filament based processGO:0032970990.011
neuron migrationGO:00017641220.011
myeloid cell differentiationGO:00300992330.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
negative regulation of cell activationGO:00508661110.011
peptide transportGO:00158331330.011
regulation of transcription from rna polymerase iii promoterGO:000635920.010
positive regulation of protein catabolic processGO:0045732600.010
response to nutrient levelsGO:00316671090.010
regulation of cell activationGO:00508652890.010
mitotic cell cycle processGO:19030471590.010
regulation of cellular response to stressGO:00801351590.010
generation of precursor metabolites and energyGO:00060911030.010
cell adhesionGO:00071553290.010
regulation of rho gtpase activityGO:0032319580.010
activation of ral gtpase activityGO:003285930.010
jnk cascadeGO:0007254720.010
thermosensory behaviorGO:004004010.010
response to oxygen levelsGO:0070482620.010
apoptotic mitochondrial changesGO:0008637480.010
negative regulation of neuron differentiationGO:00456651010.010
muscle tissue developmentGO:00605373080.010
macromolecule methylationGO:00434141200.010
spermatid developmentGO:00072861080.010
protein processingGO:00164851630.010
response to light stimulusGO:00094161350.010
regulation of cell motilityGO:20001452360.010
monosaccharide transportGO:0015749580.010
regulation of endocytosisGO:0030100690.010
heart morphogenesisGO:00030071780.010
limb developmentGO:00601731660.010

Parp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.028
disease of anatomical entityDOID:700.028
central nervous system diseaseDOID:33100.016
neurodegenerative diseaseDOID:128900.011
brain diseaseDOID:93600.010