Mus musculus

26 known processes

Parp3

poly (ADP-ribose) polymerase family, member 3

(Aliases: Adprtl3,pADPRT-3,PARP-3,AW990611,A930002C11Rik,Adprt3)

Parp3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cytokine productionGO:00018172660.092
immune effector processGO:00022523210.087
regulation of hydrolase activityGO:00513362460.082
regulation of defense responseGO:00313472330.066
nucleotide metabolic processGO:00091173320.060
muscle tissue developmentGO:00605373080.060
cellular amino acid metabolic processGO:00065201030.057
innate immune responseGO:00450871570.051
negative regulation of protein metabolic processGO:00512482820.050
leukocyte differentiationGO:00025213420.050
cellular ketone metabolic processGO:0042180840.048
regulation of cellular amino acid metabolic processGO:000652150.047
cellular amine metabolic processGO:0044106440.047
purine nucleotide catabolic processGO:00061952110.047
regulation of organelle organizationGO:00330432890.044
Human
regulation of proteolysisGO:00301621640.044
amine metabolic processGO:0009308450.043
negative regulation of cellular protein metabolic processGO:00322692470.043
ribonucleoside metabolic processGO:00091192450.043
defense response to virusGO:0051607680.043
small gtpase mediated signal transductionGO:0007264970.043
regulation of innate immune responseGO:0045088910.043
t cell activationGO:00421102890.043
protein modification by small protein conjugation or removalGO:00706472070.043
positive regulation of programmed cell deathGO:00430682180.042
activation of immune responseGO:00022531380.041
protein processingGO:00164851630.041
positive regulation of cell deathGO:00109422240.041
cytokine productionGO:00018163190.041
positive regulation of cytokine productionGO:00018191740.040
protein maturationGO:00516041760.040
apoptotic signaling pathwayGO:00971903060.039
Mouse
regulation of cellular amine metabolic processGO:0033238200.039
organic cyclic compound catabolic processGO:19013612950.039
purine containing compound metabolic processGO:00725213110.039
response to molecule of bacterial originGO:00022371430.039
ras protein signal transductionGO:0007265770.039
ribonucleotide catabolic processGO:00092612080.038
regulation of lymphocyte activationGO:00512492400.038
nucleoside phosphate metabolic processGO:00067533380.038
inflammatory responseGO:00069542440.038
nucleoside triphosphate metabolic processGO:00091412300.038
nucleobase containing small molecule metabolic processGO:00550863520.037
ribonucleotide metabolic processGO:00092592910.036
myeloid cell differentiationGO:00300992330.036
purine nucleoside metabolic processGO:00422782410.035
ribonucleoside catabolic processGO:00424542060.035
regulation of cellular ketone metabolic processGO:0010565660.035
activation of innate immune responseGO:0002218560.034
purine ribonucleotide catabolic processGO:00091542080.034
transmembrane transportGO:00550854120.034
response to lipopolysaccharideGO:00324961280.034
regulation of peptidase activityGO:0052547960.034
cellular lipid metabolic processGO:00442553230.034
purine nucleoside triphosphate metabolic processGO:00091442260.034
cation transportGO:00068123990.034
positive regulation of defense responseGO:00313491240.033
regulation of cellular component biogenesisGO:00440871810.033
interspecies interaction between organismsGO:0044419830.033
carbohydrate derivative catabolic processGO:19011362310.033
ribose phosphate metabolic processGO:00196932910.032
cellular protein complex assemblyGO:00436231160.032
regulation of protein localizationGO:00328802310.032
purine ribonucleoside catabolic processGO:00461302050.032
muscle cell differentiationGO:00426922610.032
cellular response to organonitrogen compoundGO:00714171450.031
cellular response to lipopolysaccharideGO:0071222770.031
heterocycle catabolic processGO:00467002800.031
adaptive immune responseGO:00022501550.030
positive regulation of protein modification processGO:00314012990.030
glycoprotein biosynthetic processGO:0009101890.030
Human
regulation of multi organism processGO:00439001110.030
glycosyl compound metabolic processGO:19016572460.030
protein ubiquitinationGO:00165671710.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
membrane organizationGO:00610242450.029
purine ribonucleoside metabolic processGO:00461282410.029
negative regulation of cellular amine metabolic processGO:003323910.029
purine ribonucleotide metabolic processGO:00091502900.029
positive regulation of innate immune responseGO:0045089800.029
regulation of t cell activationGO:00508631700.029
striated muscle tissue developmentGO:00147062930.029
regulation of response to woundingGO:19030341890.028
positive regulation of apoptotic processGO:00430652170.028
peptidyl amino acid modificationGO:00181933360.028
regulation of cellular catabolic processGO:00313292420.028
synaptic transmissionGO:00072683290.028
positive regulation of cellular amine metabolic processGO:003324050.028
aromatic compound catabolic processGO:00194392860.028
homeostasis of number of cellsGO:00488722100.027
lymphocyte differentiationGO:00300982420.027
regulation of cell activationGO:00508652890.027
negative regulation of molecular functionGO:00440922580.027
negative regulation of phosphorylationGO:00423261660.027
purine nucleoside triphosphate catabolic processGO:00091462030.027
nitrogen compound transportGO:00717052710.027
actin cytoskeleton organizationGO:00300362200.026
regulation of myotube differentiationGO:0010830620.026
nucleoside metabolic processGO:00091162460.026
response to organonitrogen compoundGO:00102432460.026
guanosine containing compound metabolic processGO:19010681440.026
cell adhesionGO:00071553290.026
intracellular protein transportGO:00068862040.025
ion transmembrane transportGO:00342203610.025
cellular response to molecule of bacterial originGO:0071219830.025
purine nucleotide metabolic processGO:00061633020.025
purine nucleoside catabolic processGO:00061522050.025
carbohydrate derivative biosynthetic processGO:19011371830.025
Human
rho protein signal transductionGO:0007266320.025
oxidation reduction processGO:00551143420.025
immune response regulating signaling pathwayGO:00027641250.025
response to radiationGO:00093141650.025
epithelial cell proliferationGO:00506731740.025
purine ribonucleoside triphosphate catabolic processGO:00092071990.025
mapk cascadeGO:00001652810.025
leukocyte mediated immunityGO:00024431740.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
cell substrate adhesionGO:00315891300.024
protein catabolic processGO:00301632210.024
defense response to other organismGO:00985421970.024
i kappab kinase nf kappab signalingGO:0007249850.024
nucleoside phosphate catabolic processGO:19012922220.024
negative regulation of phosphate metabolic processGO:00459361840.024
nucleoside triphosphate catabolic processGO:00091432050.024
extracellular structure organizationGO:00430621480.024
cellular chemical homeostasisGO:00550822150.024
multicellular organism growthGO:00352641610.024
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
gland developmentGO:00487323300.024
glycoprotein metabolic processGO:00091001160.023
Human
cellular response to biotic stimulusGO:0071216920.023
protein modification by small protein conjugationGO:00324461870.023
regulation of establishment of protein localizationGO:00702011810.023
nucleotide catabolic processGO:00091662170.023
cation homeostasisGO:00550802120.023
negative regulation of phosphorus metabolic processGO:00105631840.023
carbohydrate metabolic processGO:00059752300.023
Human
ubiquitin dependent protein catabolic processGO:00065111290.022
regulation of apoptotic signaling pathwayGO:20012331970.022
male gamete generationGO:00482322850.022
positive regulation of hydrolase activityGO:00513451480.022
negative regulation of protein phosphorylationGO:00019331260.022
purine containing compound catabolic processGO:00725232130.022
macromolecule catabolic processGO:00090572810.022
myotube differentiationGO:00149021050.022
glycosyl compound catabolic processGO:19016582060.022
regulation of nucleotide metabolic processGO:00061401690.022
organonitrogen compound catabolic processGO:19015652640.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.021
negative regulation of cell proliferationGO:00082852960.021
negative regulation of cellular component organizationGO:00511291940.021
cellular homeostasisGO:00197252400.021
regulation of secretionGO:00510462740.021
lymphocyte proliferationGO:00466511640.021
cellular response to lipidGO:00713961450.021
regulation of protein processingGO:0070613960.021
regulation of nucleoside metabolic processGO:00091181300.021
negative regulation of proteolysisGO:0045861740.021
single organism cell adhesionGO:00986021560.021
reactive oxygen species metabolic processGO:0072593840.021
regulation of protein catabolic processGO:00421761080.021
lymphocyte mediated immunityGO:00024491390.021
cation transmembrane transportGO:00986552660.020
regulation of purine nucleotide metabolic processGO:19005421690.020
divalent inorganic cation transportGO:00725111780.020
regulation of mapk cascadeGO:00434082480.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
fat cell differentiationGO:00454441600.020
positive regulation of proteolysisGO:0045862850.020
protein localization to membraneGO:00726571080.020
response to peptideGO:19016521360.019
negative regulation of protein modification processGO:00314001630.019
regulation of intracellular transportGO:00323861590.019
leukocyte proliferationGO:00706611720.019
negative regulation of immune system processGO:00026832090.019
regulation of ras protein signal transductionGO:00465781140.019
leukocyte migrationGO:00509001240.019
response to growth factorGO:00708481980.019
cell activation involved in immune responseGO:00022631260.019
organophosphate catabolic processGO:00464342320.019
cellular metal ion homeostasisGO:00068751510.019
regulation of anatomical structure sizeGO:00900661780.019
cellular response to acid chemicalGO:0071229680.019
cellular response to amino acid stimulusGO:0071230290.019
peptide transportGO:00158331330.019
cellular nitrogen compound catabolic processGO:00442702800.019
negative regulation of cell developmentGO:00107211690.019
nucleoside catabolic processGO:00091642060.019
regulation of protein transportGO:00512231630.018
cell type specific apoptotic processGO:00972852680.018
regulation of protein maturationGO:1903317960.018
immune response activating signal transductionGO:00027571160.018
positive regulation of lymphocyte activationGO:00512511400.018
interleukin 8 productionGO:003263740.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
gtp catabolic processGO:00061841430.018
response to acid chemicalGO:00011011110.018
protein localization to organelleGO:00333651850.018
Human
morphogenesis of a branching structureGO:00017632030.018
anion transportGO:00068201770.018
regulation of membrane potentialGO:00423911920.018
actin filament organizationGO:00070151130.018
divalent inorganic cation homeostasisGO:00725071380.017
regulation of endopeptidase activityGO:0052548890.017
positive regulation of mapk cascadeGO:00434101700.017
modification dependent protein catabolic processGO:00199411330.017
regulation of leukocyte mediated immunityGO:00027031040.017
positive regulation of cell activationGO:00508671580.017
extracellular matrix organizationGO:00301981470.017
regulation of lymphocyte proliferationGO:00506701170.017
positive regulation of purine nucleotide metabolic processGO:19005441140.017
muscle cell developmentGO:00550011330.017
striated muscle cell developmentGO:00550021250.017
angiogenesisGO:00015252010.017
cellular macromolecule catabolic processGO:00442652060.017
dna metabolic processGO:00062593030.017
organonitrogen compound biosynthetic processGO:19015661920.017
regulation of purine nucleotide catabolic processGO:00331211220.017
positive regulation of protein phosphorylationGO:00019342420.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
regulation of nucleotide catabolic processGO:00308111220.017
symbiosis encompassing mutualism through parasitismGO:0044403830.017
mitochondrion organizationGO:00070051340.017
regulation of cytoskeleton organizationGO:00514931220.016
Human
regulation of reactive oxygen species metabolic processGO:2000377400.016
actin filament polymerizationGO:0030041440.016
sensory perceptionGO:00076002450.016
modification dependent macromolecule catabolic processGO:00436321330.016
regulation of cell adhesionGO:00301551540.016
gonad developmentGO:00084061410.016
regulation of system processGO:00440572000.016
monocarboxylic acid metabolic processGO:00327871910.016
regulation of ion transportGO:00432692150.016
blood vessel morphogenesisGO:00485142850.016
microtubule based processGO:00070172360.016
Human
myeloid leukocyte differentiationGO:00025731190.016
negative regulation of intracellular signal transductionGO:19025321670.016
guanosine containing compound catabolic processGO:19010691440.016
regulation of body fluid levelsGO:00508781620.015
cellular response to cytokine stimulusGO:00713451890.015
regulation of cytoplasmic transportGO:19036491120.015
metal ion homeostasisGO:00550651890.015
regulation of cellular response to stressGO:00801351590.015
calcium ion transportGO:00068161590.015
regulation of striated muscle cell differentiationGO:0051153810.015
amide transportGO:00428861380.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
regulation of secretion by cellGO:19035302490.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
cytoplasmic transportGO:00164822340.015
sensory organ morphogenesisGO:00905962420.015
fatty acid metabolic processGO:00066311210.015
endomembrane system organizationGO:00102561470.015
endocytosisGO:00068971680.015
regulation of response to biotic stimulusGO:0002831380.015
positive regulation of protein kinase activityGO:00458601440.015
cellular response to dna damage stimulusGO:00069742070.015
ossificationGO:00015032160.015
macromolecule glycosylationGO:0043413550.014
Human
sulfur compound metabolic processGO:00067901000.014
innate immune response activating signal transductionGO:0002758500.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
divalent metal ion transportGO:00708381720.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
spermatogenesisGO:00072832840.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
defense response to bacteriumGO:00427421190.014
multicellular organismal homeostasisGO:00488711640.014
response to organic cyclic compoundGO:00140701980.014
regulation of cellular component sizeGO:00325351210.014
production of molecular mediator of immune responseGO:00024401030.014
regulation of leukocyte proliferationGO:00706631210.014
tumor necrosis factor superfamily cytokine productionGO:0071706510.014
negative regulation of cell activationGO:00508661110.014
negative regulation of lymphocyte activationGO:0051250910.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
response to light stimulusGO:00094161350.014
regulation of neuron deathGO:19012141340.014
inorganic cation transmembrane transportGO:00986622070.014
cellular protein catabolic processGO:00442571550.014
nucleocytoplasmic transportGO:00069131390.013
calcium ion homeostasisGO:00550741270.013
positive regulation of nucleotide metabolic processGO:00459811140.013
embryonic organ morphogenesisGO:00485622760.013
cellular response to growth factor stimulusGO:00713631970.013
negative regulation of defense responseGO:0031348770.013
myeloid cell homeostasisGO:00022621140.013
learning or memoryGO:00076111480.013
regulation of protein kinase activityGO:00458592320.013
regulation of cell cycleGO:00517262810.013
Human
compound eye developmentGO:004874910.013
regulation of lymphocyte mediated immunityGO:0002706840.013
proteasomal protein catabolic processGO:0010498980.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.013
viral processGO:0016032410.013
protein polymerizationGO:0051258570.013
regulation of ras gtpase activityGO:0032318880.013
protein targetingGO:00066051430.013
camera type eye developmentGO:00430102660.013
regulation of kinase activityGO:00435492490.013
regulation of inflammatory responseGO:00507271470.013
regulation of transferase activityGO:00513382630.013
actin polymerization or depolymerizationGO:0008154540.013
positive regulation of cellular component biogenesisGO:0044089940.013
positive regulation of secretionGO:00510471300.013
negative regulation of protein maturationGO:1903318790.013
nuclear transportGO:00511691390.013
anatomical structure homeostasisGO:00602491450.013
Human
cellular response to peptideGO:1901653920.013
regulation of adaptive immune responseGO:0002819900.013
t cell differentiationGO:00302171740.013
regulation of gtp catabolic processGO:00331241130.013
multicellular organismal signalingGO:0035637910.013
negative regulation of immune effector processGO:0002698550.013
neuron deathGO:00709971540.013
negative regulation of protein processingGO:0010955790.013
peptide secretionGO:00027901140.013
negative regulation of endopeptidase activityGO:0010951440.013
t cell proliferationGO:00420981200.012
chemotaxisGO:00069352470.012
respiratory system developmentGO:00605411900.012
positive regulation of mitochondrial calcium ion concentrationGO:005156130.012
inorganic ion transmembrane transportGO:00986602340.012
peptidyl tyrosine phosphorylationGO:00181081430.012
regulation of hormone levelsGO:00108172110.012
cognitionGO:00508901490.012
positive regulation of nervous system developmentGO:00519622210.012
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.012
mitotic cell cycleGO:00002781950.012
Human
circulatory system processGO:00030131970.012
nuclear importGO:0051170950.012
regulation of intracellular protein transportGO:0033157820.012
regulation of lymphocyte differentiationGO:00456191070.012
response to amino acidGO:0043200370.012
positive regulation of secretion by cellGO:19035321140.012
regulation of vesicle mediated transportGO:00606271390.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
response to nutrient levelsGO:00316671090.012
positive regulation of ras gtpase activityGO:0032320650.012
positive regulation of protein catabolic processGO:0045732600.012
negative regulation of nervous system developmentGO:00519611560.012
regulation of leukocyte differentiationGO:19021051590.012
cellular response to hormone stimulusGO:00328701500.012
blood circulationGO:00080151950.012
positive regulation of interleukin 8 productionGO:003275720.012
response to extracellular stimulusGO:00099911270.012
cellular component assembly involved in morphogenesisGO:00109271390.012
regulation of protein complex assemblyGO:0043254830.012
organelle fissionGO:00482851700.012
rhythmic processGO:00485111740.012
cellular calcium ion homeostasisGO:00068741190.012
negative regulation of hydrolase activityGO:0051346710.012
locomotory behaviorGO:00076261950.012
regulation of cell projection organizationGO:00313442060.012
positive regulation of gtp catabolic processGO:0033126850.012
type i interferon productionGO:0032606290.012
regulation of cell migrationGO:00303342190.012
organic hydroxy compound metabolic processGO:19016152030.012
organic hydroxy compound transportGO:0015850930.012
positive regulation of peptidase activityGO:0010952490.012
regulation of actin filament based processGO:0032970990.012
peptidyl tyrosine modificationGO:00182121450.012
cellular ion homeostasisGO:00068731650.011
forebrain developmentGO:00309003020.011
negative regulation of multi organism processGO:0043901680.011
lymphocyte activation involved in immune responseGO:0002285930.011
nucleoside monophosphate metabolic processGO:0009123850.011
regionalizationGO:00030023370.011
development of primary sexual characteristicsGO:00451371430.011
cell matrix adhesionGO:0007160680.011
negative regulation of cytokine productionGO:0001818840.011
viral gene expressionGO:001908030.011
carbohydrate homeostasisGO:00335001280.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
cellular response to transforming growth factor beta stimulusGO:0071560880.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
posttranscriptional regulation of gene expressionGO:00106081550.011
regulation of interleukin 8 productionGO:003267730.011
lipid biosynthetic processGO:00086101790.011
transmission of nerve impulseGO:0019226760.011
negative regulation of t cell activationGO:0050868650.011
regulation of rho protein signal transductionGO:0035023710.011
glucose homeostasisGO:00425931280.011
response to insulinGO:00328681000.011
rna interferenceGO:001624620.011
positive regulation of protein transportGO:0051222930.011
regulation of t cell proliferationGO:0042129920.011
entry into cell of other organism involved in symbiotic interactionGO:0051806150.011
skeletal system developmentGO:00015013560.011
morphogenesis of a branching epitheliumGO:00611381930.011
maintenance of locationGO:0051235890.011
regulation of feeding behaviorGO:006025930.011
skeletal muscle organ developmentGO:00605381630.011
membrane depolarizationGO:0051899640.011
positive regulation of nucleotide catabolic processGO:0030813880.011
positive regulation of cell developmentGO:00107202370.011
protein glycosylationGO:0006486550.011
Human
cellular response to peptide hormone stimulusGO:0071375920.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
organophosphate biosynthetic processGO:00904071220.011
plasma membrane organizationGO:0007009900.011
b cell activationGO:00421131610.011
neuron apoptotic processGO:00514021420.011
cell growthGO:00160491300.011
reactive oxygen species biosynthetic processGO:190340980.011
cytokine mediated signaling pathwayGO:00192211150.011
female gonad developmentGO:0008585710.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
epithelial cell developmentGO:00020641590.011
regulation of cysteine type endopeptidase activityGO:2000116650.010
wnt signaling pathwayGO:00160551880.010
epidermis developmentGO:00085441870.010
female sex differentiationGO:0046660840.010
positive regulation of kinase activityGO:00336741550.010
protein secretionGO:00093061110.010
positive regulation of immune effector processGO:00026991070.010
immunoglobulin mediated immune responseGO:0016064690.010
single organism nuclear importGO:1902593950.010
negative regulation of peptidase activityGO:0010466460.010
cytokine biosynthetic processGO:0042089680.010
cd4 positive alpha beta t cell activationGO:0035710450.010
regulation of epithelial cell proliferationGO:00506781410.010
viral transcriptionGO:001908330.010
lung developmentGO:00303241640.010
positive regulation of purine nucleotide catabolic processGO:0033123880.010
engulfment of apoptotic cellGO:004365230.010
regulation of neuron differentiationGO:00456642810.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
regulation of bindingGO:00510981110.010
negative regulation of viral transcriptionGO:003289730.010

Parp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
nervous system diseaseDOID:86300.042
sensory system diseaseDOID:005015500.023
disease of metabolismDOID:001466700.023
immune system diseaseDOID:291400.021
eye and adnexa diseaseDOID:149200.021
eye diseaseDOID:561400.021
musculoskeletal system diseaseDOID:1700.021
retinal diseaseDOID:567900.017
retinal degenerationDOID:846600.017
bone diseaseDOID:008000100.010
connective tissue diseaseDOID:6500.010