Mus musculus

0 known processes

Hmgcs1

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

(Aliases: B130032C06Rik,MGC36662,MGC98430)

Hmgcs1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular alcohol biosynthetic processGO:004410831.000
sterol metabolic processGO:0016125581.000
cholesterol biosynthetic processGO:0006695150.998
lipid biosynthetic processGO:00086101790.997
small molecule biosynthetic processGO:00442831320.995
alcohol biosynthetic processGO:0046165430.988
cellular alcohol metabolic processGO:004410730.983
alcohol metabolic processGO:00060661160.981
sterol biosynthetic processGO:0016126170.945
cholesterol metabolic processGO:0008203560.908
isoprenoid biosynthetic processGO:000829990.899
steroid metabolic processGO:00082021190.856
oxidation reduction processGO:00551143420.828
cellular lipid metabolic processGO:00442553230.819
organic hydroxy compound metabolic processGO:19016152030.756
response to stilbenoidGO:0035634220.711
steroid biosynthetic processGO:0006694470.697
long chain fatty acid biosynthetic processGO:004275950.520
fatty acid elongationGO:003049730.490
organic hydroxy compound biosynthetic processGO:1901617770.472
sphingolipid metabolic processGO:0006665450.469
long chain fatty acid metabolic processGO:0001676260.438
cellular biogenic amine metabolic processGO:0006576280.399
organonitrogen compound biosynthetic processGO:19015661920.368
fatty acid elongation unsaturated fatty acidGO:001936820.282
sphingolipid biosynthetic processGO:0030148260.259
lipid modificationGO:0030258650.236
sterol transmembrane transportGO:003538220.190
rhodopsin mediated signaling pathwayGO:001605640.187
liver developmentGO:0001889660.162
fatty acid metabolic processGO:00066311210.157
demethylationGO:0070988230.154
lipid transportGO:0006869980.150
monocarboxylic acid biosynthetic processGO:0072330610.147
mating behavior sex discriminationGO:004804710.144
glutamate biosynthetic processGO:000653720.143
monocarboxylic acid metabolic processGO:00327871910.135
regulation of phospholipid catabolic processGO:006069620.123
regulation of phosphatidylcholine catabolic processGO:001089920.121
small molecule catabolic processGO:0044282710.120
carboxylic acid biosynthetic processGO:0046394860.109
organic acid biosynthetic processGO:0016053860.107
response to radiationGO:00093141650.097
adaptation of rhodopsin mediated signalingGO:001606220.094
spermatid differentiationGO:00485151150.092
regulation of cellular amine metabolic processGO:0033238200.090
endocytosisGO:00068971680.088
regulation of lipid metabolic processGO:00192161180.084
sterol transportGO:0015918380.081
very long chain fatty acid biosynthetic processGO:004276120.075
negative regulation of multi organism processGO:0043901680.074
alpha amino acid biosynthetic processGO:1901607150.073
lipid localizationGO:00108761260.071
ribonucleotide metabolic processGO:00092592910.071
response to nutrient levelsGO:00316671090.070
cellular amino acid metabolic processGO:00065201030.070
cellular amino acid biosynthetic processGO:0008652220.067
triglyceride biosynthetic processGO:0019432170.066
neutral lipid biosynthetic processGO:0046460180.065
regulation of synaptic growth at neuromuscular junctionGO:000858240.064
establishment or maintenance of cytoskeleton polarityGO:003095220.063
cellular ketone metabolic processGO:0042180840.062
negative regulation of intracellular signal transductionGO:19025321670.059
negative regulation of molecular functionGO:00440922580.059
purine nucleotide metabolic processGO:00061633020.056
fatty acid biosynthetic processGO:0006633410.056
regulation of cellular ketone metabolic processGO:0010565660.054
microtubule cytoskeleton organizationGO:00002261570.053
coenzyme biosynthetic processGO:0009108230.053
glycosyl compound metabolic processGO:19016572460.050
regulation of phospholipid biosynthetic processGO:007107130.050
tricarboxylic acid metabolic processGO:007235050.048
response to organic cyclic compoundGO:00140701980.048
phospholipid catabolic processGO:000939550.047
organic hydroxy compound catabolic processGO:1901616250.047
regulation of triglyceride metabolic processGO:0090207170.047
nucleotide metabolic processGO:00091173320.046
positive regulation of cellular amine metabolic processGO:003324050.045
purine nucleoside metabolic processGO:00422782410.044
ras protein signal transductionGO:0007265770.044
nucleoside triphosphate metabolic processGO:00091412300.044
ribonucleoside metabolic processGO:00091192450.043
response to phenylpropanoidGO:0080184220.041
response to peptideGO:19016521360.041
ribose phosphate metabolic processGO:00196932910.039
positive regulation of lipid metabolic processGO:0045834400.039
cholesterol importGO:007050820.038
small gtpase mediated signal transductionGO:0007264970.038
positive regulation of mapk cascadeGO:00434101700.038
positive regulation of growthGO:00459271040.037
locomotory behaviorGO:00076261950.037
gland developmentGO:00487323300.037
response to extracellular stimulusGO:00099911270.037
response to organonitrogen compoundGO:00102432460.037
hormone secretionGO:00468791280.035
cellular amine metabolic processGO:0044106440.035
regulation of organelle organizationGO:00330432890.034
positive regulation of triglyceride metabolic processGO:009020890.034
regulation of hormone levelsGO:00108172110.033
regulation of vesicle mediated transportGO:00606271390.033
organophosphate catabolic processGO:00464342320.033
nucleobase containing small molecule metabolic processGO:00550863520.032
forebrain developmentGO:00309003020.031
response to monosaccharideGO:0034284670.031
glutamate metabolic processGO:000653690.030
establishment or maintenance of bipolar cell polarityGO:0061245210.030
purine ribonucleoside metabolic processGO:00461282410.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
negative regulation of protein metabolic processGO:00512482820.029
nucleoside metabolic processGO:00091162460.029
regulation of cytoskeleton organizationGO:00514931220.028
nucleoside bisphosphate biosynthetic processGO:003386660.028
regulation of cellular amino acid metabolic processGO:000652150.028
cholesterol homeostasisGO:0042632440.028
cellular ketone body metabolic processGO:004695030.027
skin developmentGO:00435882200.027
positive regulation of cholesterol biosynthetic processGO:004554230.027
amine metabolic processGO:0009308450.027
pallium developmentGO:00215431200.027
organonitrogen compound catabolic processGO:19015652640.026
cellular response to carbohydrate stimulusGO:0071322500.026
maintenance of locationGO:0051235890.026
nucleoside phosphate catabolic processGO:19012922220.026
multicellular organism growthGO:00352641610.026
oocyte constructionGO:000730820.026
positive regulation of creb transcription factor activityGO:003279340.025
positive regulation of transferase activityGO:00513471670.024
ethanolamine containing compound metabolic processGO:0042439180.024
positive regulation of protein modification processGO:00314012990.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
detection of abiotic stimulusGO:0009582600.024
regulation of secretionGO:00510462740.024
spermatid developmentGO:00072861080.023
purine ribonucleotide metabolic processGO:00091502900.023
negative regulation of growthGO:0045926990.023
cellularizationGO:000734910.023
sterol homeostasisGO:0055092450.023
ribonucleotide biosynthetic processGO:0009260590.023
negative regulation of synapse assemblyGO:005196430.022
actin filament organizationGO:00070151130.022
asymmetric stem cell divisionGO:009872230.022
male gamete generationGO:00482322850.022
ribonucleoside bisphosphate metabolic processGO:003387590.022
carbohydrate derivative catabolic processGO:19011362310.022
negative regulation of protein serine threonine kinase activityGO:0071901490.022
molting cycleGO:0042303900.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
protein catabolic processGO:00301632210.021
mapk cascadeGO:00001652810.021
glycerolipid metabolic processGO:00464861220.021
maternal determination of anterior posterior axis embryoGO:000835820.021
ribose phosphate biosynthetic processGO:0046390590.021
response to light stimulusGO:00094161350.021
rho protein signal transductionGO:0007266320.021
positive regulation of cell projection organizationGO:0031346950.021
regulation of cell motilityGO:20001452360.020
establishment or maintenance of cell polarityGO:0007163860.020
regulation of cellular catabolic processGO:00313292420.020
regulation of transferase activityGO:00513382630.020
response to oxidative stressGO:00069791230.020
mitochondrion organizationGO:00070051340.020
organic acid catabolic processGO:0016054510.020
nucleoside phosphate metabolic processGO:00067533380.019
gtp catabolic processGO:00061841430.019
rhythmic processGO:00485111740.019
negative regulation of phosphorus metabolic processGO:00105631840.019
neutral lipid metabolic processGO:0006638570.019
response to steroid hormoneGO:0048545560.019
anion transportGO:00068201770.019
response to yeastGO:000187860.019
purine ribonucleotide catabolic processGO:00091542080.019
defense response to bacteriumGO:00427421190.019
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.019
negative regulation of protein phosphorylationGO:00019331260.018
asymmetric neuroblast divisionGO:005505910.018
response to peptide hormoneGO:00434341270.018
lipid catabolic processGO:0016042690.018
cellular response to extracellular stimulusGO:0031668810.018
receptor biosynthetic processGO:003280030.018
negative regulation of cellular protein metabolic processGO:00322692470.018
insulin secretionGO:0030073890.018
negative regulation of nervous system developmentGO:00519611560.018
actin cytoskeleton organizationGO:00300362200.018
negative regulation of cholesterol transportGO:003237540.018
dna metabolic processGO:00062593030.018
cell divisionGO:00513011200.017
spermatogenesisGO:00072832840.017
intracellular mrna localizationGO:000829840.017
cellular respirationGO:0045333380.017
cellular protein complex assemblyGO:00436231160.017
negative regulation of cellular component organizationGO:00511291940.017
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.017
microtubule based processGO:00070172360.017
cytoplasmic transportGO:00164822340.017
sensory organ morphogenesisGO:00905962420.017
regulation of membrane potentialGO:00423911920.017
lung developmentGO:00303241640.017
fatty acid beta oxidationGO:0006635160.017
cellular transition metal ion homeostasisGO:0046916320.017
regulation of cell migrationGO:00303342190.017
cellular response to organonitrogen compoundGO:00714171450.017
ribonucleoside triphosphate catabolic processGO:00092031990.016
iron ion homeostasisGO:0055072360.016
cell junction maintenanceGO:003433140.016
genitalia developmentGO:0048806370.016
regulation of cell morphogenesis involved in differentiationGO:00107691510.016
respiratory tube developmentGO:00303231670.016
aromatic compound catabolic processGO:00194392860.016
positive regulation of cell developmentGO:00107202370.016
carboxylic acid catabolic processGO:0046395510.016
regulation of ras protein signal transductionGO:00465781140.016
cellular chemical homeostasisGO:00550822150.016
nucleotide catabolic processGO:00091662170.016
negative regulation of phosphorylationGO:00423261660.016
positive regulation of cell adhesionGO:0045785800.016
positive regulation of cell motilityGO:20001471160.016
organophosphate biosynthetic processGO:00904071220.016
retrograde transport endosome to golgiGO:004214720.016
ion transmembrane transportGO:00342203610.016
regulation of protein complex assemblyGO:0043254830.016
regulation of neuron projection developmentGO:00109751690.015
energy derivation by oxidation of organic compoundsGO:0015980770.015
regulation of phosphatidylcholine biosynthetic processGO:200124520.015
purine containing compound metabolic processGO:00725213110.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
membrane organizationGO:00610242450.015
muscle system processGO:00030121410.015
meiotic cell cycleGO:00513211220.015
fat cell differentiationGO:00454441600.015
cellular lipid catabolic processGO:0044242520.015
regulation of cell cycleGO:00517262810.015
regulation of kinase activityGO:00435492490.015
acylglycerol metabolic processGO:0006639550.015
membrane lipid metabolic processGO:0006643530.015
negative regulation of phosphate metabolic processGO:00459361840.015
endomembrane system organizationGO:00102561470.015
protein localization to membraneGO:00726571080.015
cellular response to lipidGO:00713961450.015
formation of organ boundaryGO:001016010.015
low density lipoprotein particle clearanceGO:003438380.015
regulation of neuron differentiationGO:00456642810.015
regulation of multi organism processGO:00439001110.015
cell growthGO:00160491300.015
generation of precursor metabolites and energyGO:00060911030.015
transmission of nerve impulseGO:0019226760.015
g protein coupled receptor signaling pathwayGO:00071862430.015
oocyte axis specificationGO:000730920.014
lipid homeostasisGO:0055088630.014
thioester metabolic processGO:0035383190.014
smoothened signaling pathwayGO:00072241050.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
regulation of ion transportGO:00432692150.014
positive regulation of protein kinase activityGO:00458601440.014
regulation of cell projection organizationGO:00313442060.014
response to inorganic substanceGO:0010035960.014
triglyceride metabolic processGO:0006641510.014
multicellular organismal signalingGO:0035637910.014
carbohydrate homeostasisGO:00335001280.014
stem cell developmentGO:00488642190.014
positive regulation of nervous system developmentGO:00519622210.014
cofactor biosynthetic processGO:0051188410.014
nucleotide biosynthetic processGO:0009165780.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
stem cell differentiationGO:00488632680.014
glutamine family amino acid metabolic processGO:0009064150.014
dicarboxylic acid biosynthetic processGO:004365050.014
regulation of cellular component biogenesisGO:00440871810.013
compound eye developmentGO:004874910.013
establishment of protein localization to membraneGO:0090150540.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
metal ion homeostasisGO:00550651890.013
ameboidal type cell migrationGO:00016671280.013
tissue migrationGO:0090130680.013
telencephalon developmentGO:00215371860.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
inorganic cation transmembrane transportGO:00986622070.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
regulation of mapk cascadeGO:00434082480.013
negative regulation of protein modification processGO:00314001630.013
acyl coa biosynthetic processGO:007161670.013
carbohydrate derivative biosynthetic processGO:19011371830.013
cation transmembrane transportGO:00986552660.013
regulation of exocytosisGO:0017157610.013
blood vessel morphogenesisGO:00485142850.013
activation of adenylate cyclase activityGO:000719040.013
innate immune responseGO:00450871570.013
regulation of cellular component sizeGO:00325351210.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.013
purine nucleoside triphosphate metabolic processGO:00091442260.013
positive regulation of dna templated transcription elongationGO:003278620.013
regulation of lipid storageGO:0010883200.013
peptide metabolic processGO:0006518460.013
phosphorylated carbohydrate dephosphorylationGO:004683840.013
wnt signaling pathwayGO:00160551880.013
neuronal action potentialGO:0019228540.013
oocyte anterior posterior axis specificationGO:000731420.013
cellular amide metabolic processGO:0043603580.013
nucleoside biosynthetic processGO:0009163210.012
positive regulation of secretionGO:00510471300.012
histone modificationGO:00165701590.012
dicarboxylic acid metabolic processGO:0043648180.012
development of primary sexual characteristicsGO:00451371430.012
regulation of receptor biosynthetic processGO:001086920.012
positive regulation of secretion by cellGO:19035321140.012
amide transportGO:00428861380.012
response to starvationGO:0042594650.012
positive regulation of steroid biosynthetic processGO:001089340.012
cellular response to external stimulusGO:0071496880.012
limbic system developmentGO:0021761720.012
organelle disassemblyGO:190300820.012
positive regulation of cholesterol storageGO:001088630.012
isoprenoid metabolic processGO:0006720290.012
defense response to gram positive bacteriumGO:0050830500.012
fatty acid oxidationGO:0019395280.012
cellular homeostasisGO:00197252400.012
mrna metabolic processGO:0016071840.012
female sex differentiationGO:0046660840.012
positive regulation of neuron differentiationGO:00456661410.012
organic cyclic compound catabolic processGO:19013612950.012
cellular carbohydrate metabolic processGO:00442621190.012
associative learningGO:0008306610.012
transmembrane transportGO:00550854120.012
glucose homeostasisGO:00425931280.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.012
regulation of defense responseGO:00313472330.012
cell fate determination involved in pattern specificationGO:006058210.012
regulation of transmembrane transportGO:00347621280.012
regulation of actin filament based processGO:0032970990.012
positive regulation of triglyceride biosynthetic processGO:001086760.012
osteoclast differentiationGO:0030316620.012
peptide hormone secretionGO:00300721090.012
regulation of homeostatic processGO:00328441820.012
nitrogen compound transportGO:00717052710.012
nucleoside catabolic processGO:00091642060.012
response to insulinGO:00328681000.012
carbon catabolite regulation of transcriptionGO:004599040.012
growth involved in symbiotic interactionGO:0044110230.012
negative regulation of neuron apoptotic processGO:0043524920.012
organic acid transportGO:00158491010.012
glutathione metabolic processGO:0006749160.011
cofactor metabolic processGO:0051186800.011
neural precursor cell proliferationGO:00613511210.011
synapse organizationGO:00508081250.011
establishment or maintenance of apical basal cell polarityGO:0035088210.011
sensory perceptionGO:00076002450.011
synaptic transmissionGO:00072683290.011
organic hydroxy compound transportGO:0015850930.011
learningGO:0007612980.011
purine containing compound catabolic processGO:00725232130.011
germ cell developmentGO:00072811850.011
urogenital system developmentGO:00016552610.011
development of primary female sexual characteristicsGO:0046545730.011
purine nucleoside catabolic processGO:00061522050.011
protein modification by small protein conjugationGO:00324461870.011
exocytosisGO:00068871210.011
learning or memoryGO:00076111480.011
angiogenesisGO:00015252010.011
developmental cell growthGO:0048588840.011
cell cell junction organizationGO:0045216720.011
cellular nitrogen compound catabolic processGO:00442702800.011
posttranscriptional regulation of gene expressionGO:00106081550.011
chemotaxisGO:00069352470.011
camera type eye developmentGO:00430102660.011
nucleoside phosphate biosynthetic processGO:1901293790.011
lipid oxidationGO:0034440290.011
nadph regenerationGO:000674020.011
action potentialGO:0001508780.011
inorganic ion transmembrane transportGO:00986602340.011
protein modification by small protein conjugation or removalGO:00706472070.011
microtubule based movementGO:0007018840.011
tissue homeostasisGO:00018941150.011
cellular protein complex disassemblyGO:0043624360.011
localization within membraneGO:005166840.011
regulation of protein kinase activityGO:00458592320.011
macromolecule deacylationGO:0098732370.011
response to acid chemicalGO:00011011110.011
inter male aggressive behaviorGO:000212130.011
very long chain fatty acid metabolic processGO:000003880.011
organelle fissionGO:00482851700.011
cell substrate adhesionGO:00315891300.011
canonical wnt signaling pathwayGO:00600701300.011
macromolecule catabolic processGO:00090572810.011
peptidyl amino acid modificationGO:00181933360.010
receptor mediated endocytosisGO:0006898510.010
interleukin 8 productionGO:003263740.010
cellular response to gamma radiationGO:007148040.010
purine containing compound biosynthetic processGO:0072522700.010
cellular response to nutrient levelsGO:0031669640.010
muscle cell differentiationGO:00426922610.010
regulation of triglyceride biosynthetic processGO:0010866100.010
monocarboxylic acid transportGO:0015718440.010
regulation of ion transmembrane transportGO:00347651190.010
leukocyte differentiationGO:00025213420.010
positive regulation of organelle organizationGO:00106381280.010
regulation of apoptotic signaling pathwayGO:20012331970.010
ribonucleotide catabolic processGO:00092612080.010
cerebral cortex developmentGO:0021987860.010
regulation of protein serine threonine kinase activityGO:00719001570.010
epithelium migrationGO:0090132630.010
defense response to other organismGO:00985421970.010
negative regulation of mapk cascadeGO:0043409650.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010

Hmgcs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.157
inherited metabolic disorderDOID:65500.157
disease of cellular proliferationDOID:1456600.091
cancerDOID:16200.057
lipid metabolism disorderDOID:314600.024
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018