Mus musculus

123 known processes

Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

(Aliases: PAI1,PAI-1,Planh1)

Serpine1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of protein modification processGO:00314012990.690
leukocyte differentiationGO:00025213420.547
reactive oxygen species metabolic processGO:0072593840.520
cell adhesionGO:00071553290.507
Human Mouse
regulation of mapk cascadeGO:00434082480.452
intussusceptive angiogenesisGO:000204120.445
regulation of transferase activityGO:00513382630.429
cellular response to growth factor stimulusGO:00713631970.429
regulation of peptidase activityGO:0052547960.407
single organismal cell cell adhesionGO:00163371310.380
Mouse
wound healingGO:00420601570.374
positive regulation of mapk cascadeGO:00434101700.359
positive regulation of neutrophil mediated killing of symbiont cellGO:007096110.349
striated muscle tissue developmentGO:00147062930.333
positive regulation of sphingolipid biosynthetic processGO:009015410.318
response to growth factorGO:00708481980.303
placenta developmentGO:00018901400.301
Rat
skeletal muscle organ developmentGO:00605381630.301
regulation of apoptotic signaling pathwayGO:20012331970.297
Human
regulation of reactive oxygen species metabolic processGO:2000377400.292
positive regulation of t helper 1 cell differentiationGO:004562740.283
connective tissue developmentGO:00614481790.279
regulation of neutrophil mediated killing of gram negative bacteriumGO:007095110.268
positive regulation of cell deathGO:00109422240.263
regulation of kinase activityGO:00435492490.258
single organism cell adhesionGO:00986021560.255
Mouse
positive regulation of programmed cell deathGO:00430682180.250
response to radiationGO:00093141650.247
apoptotic signaling pathwayGO:00971903060.243
Human
positive regulation of cell adhesionGO:0045785800.242
regulation of response to woundingGO:19030341890.230
rhombomere 5 developmentGO:002157140.222
extracellular matrix organizationGO:00301981470.222
positive regulation of proteolysisGO:0045862850.221
sphingolipid biosynthetic processGO:0030148260.220
positive regulation of cytokine productionGO:00018191740.219
Human
protein maturationGO:00516041760.219
regulation of cell motilityGO:20001452360.218
Human Rat
positive regulation of leukocyte differentiationGO:1902107860.213
blood vessel morphogenesisGO:00485142850.210
skeletal system developmentGO:00015013560.209
regulation of cellular response to stressGO:00801351590.207
response to fibroblast growth factorGO:0071774470.203
Rat
gland developmentGO:00487323300.201
Mouse
sphingolipid metabolic processGO:0006665450.200
regulation of sphingolipid biosynthetic processGO:009015310.197
positive regulation of apoptotic processGO:00430652170.197
regulation of protein serine threonine kinase activityGO:00719001570.183
fibroblast growth factor receptor signaling pathwayGO:0008543460.183
cellular response to transforming growth factor beta stimulusGO:0071560880.179
negative regulation of protein metabolic processGO:00512482820.179
regulation of ceramide biosynthetic processGO:200030310.178
muscle tissue developmentGO:00605373080.175
t cell activationGO:00421102890.173
cell chemotaxisGO:0060326810.169
Human
regulation of angiogenesisGO:0045765810.167
regulation of rhodopsin gene expressionGO:000746830.163
regulation of map kinase activityGO:00434051200.162
regulation of endopeptidase activityGO:0052548890.158
regulation of hydrolase activityGO:00513362460.155
mapk cascadeGO:00001652810.152
neutrophil mediated killing of gram negative bacteriumGO:007094540.152
response to transforming growth factor betaGO:0071559880.151
nucleobase containing small molecule metabolic processGO:00550863520.149
regulation of protein transportGO:00512231630.147
lung developmentGO:00303241640.146
regulation of cellular catabolic processGO:00313292420.144
cartilage developmentGO:00512161400.142
extracellular structure organizationGO:00430621480.140
carbohydrate metabolic processGO:00059752300.139
axonogenesisGO:00074092740.139
regulation of cell adhesionGO:00301551540.138
Human Mouse
inflammatory responseGO:00069542440.138
Human
muscle cell developmentGO:00550011330.136
nucleoside phosphate metabolic processGO:00067533380.136
wound healing involved in inflammatory responseGO:000224640.136
regulation of thymocyte migrationGO:200041020.135
positive regulation of reactive oxygen species metabolic processGO:2000379110.134
regulation of nucleotide metabolic processGO:00061401690.133
regulation of neutrophil mediated killing of symbiont cellGO:007094920.131
regulation of cell cycleGO:00517262810.130
regulation of proteolysisGO:00301621640.128
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.127
thymocyte migrationGO:007267920.127
cellular amine metabolic processGO:0044106440.126
camera type eye developmentGO:00430102660.124
cellular amino acid metabolic processGO:00065201030.124
positive regulation of hematopoietic stem cell proliferationGO:190203520.123
regulation of cytokine productionGO:00018172660.120
Human
response to inorganic substanceGO:0010035960.118
Rat
negative regulation of intracellular signal transductionGO:19025321670.118
Mouse
membrane lipid biosynthetic processGO:0046467320.117
respiratory tube developmentGO:00303231670.116
cell substrate adhesionGO:00315891300.116
Human
response to organic cyclic compoundGO:00140701980.115
Rat
muscle cell differentiationGO:00426922610.114
regulation of organelle organizationGO:00330432890.112
basement membrane organizationGO:007171180.111
multicellular organismal homeostasisGO:00488711640.111
myeloid cell differentiationGO:00300992330.110
positive regulation of phospholipase activityGO:001051830.108
fat cell differentiationGO:00454441600.107
chemotaxisGO:00069352470.107
Human
inflammatory response to woundingGO:009059440.107
intrinsic apoptotic signaling pathwayGO:00971931320.106
positive regulation of neutrophil mediated cytotoxicityGO:007096010.106
positive regulation of protein kinase activityGO:00458601440.106
cytokine productionGO:00018163190.105
Human
embryonic placenta developmentGO:0001892980.104
regulation of defense responseGO:00313472330.102
Human
regulation of fat cell differentiationGO:0045598810.102
positive regulation of b cell chemotaxisGO:200053820.101
negative regulation of molecular functionGO:00440922580.100
lens development in camera type eyeGO:0002088620.100
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.098
response to ionizing radiationGO:0010212420.097
brain segmentationGO:003528430.097
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.097
cation homeostasisGO:00550802120.097
regulation of cell growthGO:0001558910.097
Mouse
chondroblast differentiationGO:006059120.096
regulation of system processGO:00440572000.095
skeletal system morphogenesisGO:00487052030.093
regulation of neuron deathGO:19012141340.092
regulation of cellular amino acid metabolic processGO:000652150.092
cell growthGO:00160491300.092
Mouse
synaptic transmissionGO:00072683290.091
Mouse
cellular response to extracellular stimulusGO:0031668810.090
regulation of chondrocyte differentiationGO:0032330330.090
regulation of leukocyte differentiationGO:19021051590.090
positive regulation of rhodopsin gene expressionGO:004587220.089
negative regulation of cellular protein metabolic processGO:00322692470.088
carbohydrate derivative biosynthetic processGO:19011371830.088
positive regulation of peptidase activityGO:0010952490.088
respiratory system developmentGO:00605411900.087
positive regulation of protein phosphorylationGO:00019342420.085
cation transportGO:00068123990.085
Mouse Rat
regulation of homeostatic processGO:00328441820.085
placenta blood vessel developmentGO:0060674310.084
covalent chromatin modificationGO:00165691630.084
negative regulation of phosphorus metabolic processGO:00105631840.082
positive regulation of endopeptidase activityGO:0010950430.082
myeloid leukocyte differentiationGO:00025731190.081
negative regulation of protein phosphorylationGO:00019331260.081
regulation of cell migrationGO:00303342190.080
Human Rat
cell type specific apoptotic processGO:00972852680.080
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.080
cellular response to inorganic substanceGO:0071241370.079
Rat
translationGO:0006412930.079
response to decreased oxygen levelsGO:0036293590.079
Rat
regulation of cell substrate adhesionGO:0010810730.079
Human
muscle system processGO:00030121410.077
cell recognitionGO:0008037830.076
cellular response to oxidative stressGO:0034599760.075
Rat
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycleGO:003166010.075
regulation of secretion by cellGO:19035302490.075
stem cell differentiationGO:00488632680.074
positive regulation of cell developmentGO:00107202370.074
urogenital system developmentGO:00016552610.073
glycoprotein biosynthetic processGO:0009101890.073
regulation of cartilage developmentGO:0061035440.073
epithelial cell proliferationGO:00506731740.072
positive regulation of kinase activityGO:00336741550.072
positive regulation of eosinophil migrationGO:200041820.071
positive regulation of hydrolase activityGO:00513451480.071
purine nucleotide metabolic processGO:00061633020.071
positive regulation of epithelial cell proliferationGO:0050679680.070
response to organonitrogen compoundGO:00102432460.070
Rat
cellular response to fibroblast growth factor stimulusGO:0044344470.070
Rat
glycoprotein metabolic processGO:00091001160.070
anion transportGO:00068201770.070
purine containing compound metabolic processGO:00725213110.069
response to steroid hormoneGO:0048545560.069
Rat
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.069
macromolecule deacylationGO:0098732370.068
keratinocyte migrationGO:005154630.067
Rat
regulation of neuron projection developmentGO:00109751690.067
regulation of cell activationGO:00508652890.067
Mouse
nucleotide metabolic processGO:00091173320.067
regulation of neutrophil mediated killing of fungusGO:007095310.067
regulation of neuron apoptotic processGO:00435231220.066
positive regulation of stem cell proliferationGO:2000648590.066
t cell differentiationGO:00302171740.066
ossificationGO:00015032160.065
anatomical structure homeostasisGO:00602491450.065
regulation of bmp signaling pathwayGO:0030510600.065
negative regulation of fat cell differentiationGO:0045599360.065
striated muscle cell developmentGO:00550021250.065
regulation of erk1 and erk2 cascadeGO:0070372710.064
regulation of histone deacetylationGO:0031063120.064
regulation of eosinophil migrationGO:200041620.064
erk1 and erk2 cascadeGO:0070371770.063
extrinsic apoptotic signaling pathwayGO:00971911260.063
Human
cellular ketone metabolic processGO:0042180840.063
labyrinthine layer morphogenesisGO:0060713210.063
regulation of protein kinase activityGO:00458592320.063
regulation of neuron differentiationGO:00456642810.062
eye photoreceptor cell developmentGO:0042462310.062
response to light stimulusGO:00094161350.061
positive regulation of lipid biosynthetic processGO:0046889180.061
regulation of secretionGO:00510462740.061
chromatin organizationGO:00063252060.061
eosinophil migrationGO:007267730.061
response to peptideGO:19016521360.060
Rat
immune effector processGO:00022523210.060
purine ribonucleotide metabolic processGO:00091502900.060
negative regulation of response to woundingGO:1903035770.060
metal ion homeostasisGO:00550651890.060
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.060
labyrinthine layer developmentGO:0060711490.059
branching morphogenesis of an epithelial tubeGO:00487541590.059
negative regulation of neuron apoptotic processGO:0043524920.059
mitotic cell cycle processGO:19030471590.058
lipid biosynthetic processGO:00086101790.058
regulation of stem cell proliferationGO:0072091780.058
divalent metal ion transportGO:00708381720.057
Rat
response to metal ionGO:0010038470.057
Rat
myotube differentiationGO:00149021050.057
regulation of neutrophil mediated cytotoxicityGO:007094820.057
chromatin modificationGO:00165681870.056
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.055
morphogenesis of a branching structureGO:00017632030.055
regulation of establishment of protein localizationGO:00702011810.055
ribonucleotide metabolic processGO:00092592910.055
regulation of neutrophil mediated killing of bacteriumGO:007095010.054
i kappab kinase nf kappab signalingGO:0007249850.054
mitotic cell cycleGO:00002781950.054
regulation of lipase activityGO:0060191150.054
circulatory system processGO:00030131970.054
positive regulation of cell migrationGO:00303351090.054
Human Rat
neutrophil chemotaxisGO:0030593360.054
peptidyl amino acid modificationGO:00181933360.053
response to molecule of bacterial originGO:00022371430.053
Human Rat
cellular metal ion homeostasisGO:00068751510.053
axon regenerationGO:0031103120.053
negative regulation of protein maturationGO:1903318790.053
regulation of histone modificationGO:0031056560.052
response to oxidative stressGO:00069791230.052
Rat
adult behaviorGO:00305341350.052
positive regulation of angiogenesisGO:0045766460.052
cellular response to metal ionGO:0071248310.051
Rat
connective tissue replacement involved in inflammatory response wound healingGO:000224830.051
smooth muscle contractionGO:0006939440.051
calcium ion homeostasisGO:00550741270.051
regulation of chromosome organizationGO:0033044830.051
skin developmentGO:00435882200.051
regulation of cell projection organizationGO:00313442060.050
ceramide biosynthetic processGO:0046513200.050
response to calcium ionGO:0051592200.049
elastic fiber assemblyGO:004825140.049
regulation of myotube differentiationGO:0010830620.049
response to peptide hormoneGO:00434341270.049
Rat
regulation of inflammatory responseGO:00507271470.049
Human
morphogenesis of a branching epitheliumGO:00611381930.049
granulocyte migrationGO:0097530430.049
chondrocyte differentiationGO:0002062720.048
regulation of protein localizationGO:00328802310.048
positive regulation of lymphocyte activationGO:00512511400.048
developmental cell growthGO:0048588840.048
rhythmic processGO:00485111740.047
response to insulinGO:00328681000.047
Rat
lung alveolus developmentGO:0048286450.047
positive regulation of protein serine threonine kinase activityGO:00719021060.046
organonitrogen compound biosynthetic processGO:19015661920.046
regulation of cysteine type endopeptidase activityGO:2000116650.046
cd4 positive alpha beta t cell cytokine productionGO:003574340.046
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.046
cardiac septum developmentGO:0003279590.046
eye photoreceptor cell differentiationGO:0001754410.046
negative regulation of striated muscle cell differentiationGO:0051154140.046
positive regulation of erk1 and erk2 cascadeGO:0070374470.046
regulation of fibrinolysisGO:005191710.045
Human
cognitionGO:00508901490.045
chorio allantoic fusionGO:006071080.045
leukocyte migrationGO:00509001240.044
Human
regulation of ossificationGO:00302781120.044
wound healing spreading of cellsGO:004431980.044
positive regulation of cell motilityGO:20001471160.044
Human Rat
angiogenesisGO:00015252010.044
cellular response to lipidGO:00713961450.043
Human Rat
positive regulation of map kinase activityGO:0043406840.043
positive regulation of cell activationGO:00508671580.043
regulation of syncytium formation by plasma membrane fusionGO:0060142230.043
tissue homeostasisGO:00018941150.042
regulation of hematopoietic stem cell proliferationGO:190203330.042
cellular response to organic cyclic compoundGO:0071407870.042
Rat
osteoclast differentiationGO:0030316620.042
heart morphogenesisGO:00030071780.041
neuron projection regenerationGO:0031102140.041
t cell differentiation in thymusGO:0033077770.041
protein secretionGO:00093061110.041
purine nucleoside triphosphate metabolic processGO:00091442260.041
sequestering of calcium ionGO:0051208180.040
myeloid leukocyte migrationGO:0097529570.040
Human
transforming growth factor beta2 productionGO:003290620.040
metanephric glomerular mesangium developmentGO:007222330.040
cellular lipid metabolic processGO:00442553230.040
cellular nitrogen compound catabolic processGO:00442702800.040
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.040
embryonic placenta morphogenesisGO:0060669250.039
granulocyte chemotaxisGO:0071621390.039
calcium ion transportGO:00068161590.039
Rat
regulation of leukocyte mediated immunityGO:00027031040.039
negative regulation of phosphorylationGO:00423261660.039
regulation of cellular component biogenesisGO:00440871810.039
ventricular septum developmentGO:0003281420.039
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.039
cellular calcium ion homeostasisGO:00068741190.039
negative regulation of proteolysisGO:0045861740.039
mature dendritic cell differentiationGO:009702930.039
regulation of protein processingGO:0070613960.038
regulation of protein maturationGO:1903317960.038
negative regulation of myoblast differentiationGO:0045662180.038
lymphocyte differentiationGO:00300982420.038
regulation of lipid biosynthetic processGO:0046890540.038
reactive oxygen species biosynthetic processGO:190340980.038
muscle contractionGO:00069361010.038
oxidation reduction processGO:00551143420.038
neutrophil migrationGO:1990266370.037
hexose metabolic processGO:0019318980.037
positive regulation of lipid metabolic processGO:0045834400.037
organic acid transportGO:00158491010.037
protein glycosylationGO:0006486550.037
skeletal muscle cell differentiationGO:0035914660.037
phagocytosisGO:0006909660.037
integrin mediated signaling pathwayGO:0007229270.036
multicellular organismal macromolecule metabolic processGO:0044259190.036
jnk cascadeGO:0007254720.036
sensory system developmentGO:004888030.036
negative regulation of endopeptidase activityGO:0010951440.036
purine ribonucleotide catabolic processGO:00091542080.036
purine containing compound catabolic processGO:00725232130.036
interleukin 12 secretionGO:007261030.036
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.036
divalent inorganic cation homeostasisGO:00725071380.036
positive regulation of vasoconstrictionGO:004590740.036
protein kinase b signalingGO:0043491740.036
negative regulation of myotube differentiationGO:001083290.036
cellular response to dna damage stimulusGO:00069742070.035
compound eye developmentGO:004874910.035
transforming growth factor beta receptor signaling pathwayGO:0007179710.035
positive regulation of t helper 1 cell cytokine productionGO:200055610.035
purine ribonucleoside triphosphate metabolic processGO:00092052200.035
superoxide metabolic processGO:0006801270.035
ribonucleoside triphosphate metabolic processGO:00091992200.034
tumor necrosis factor productionGO:0032640500.034
negative regulation of neuron deathGO:1901215980.034
cellular response to biotic stimulusGO:0071216920.034
Human
circadian behaviorGO:0048512130.034
carbohydrate biosynthetic processGO:0016051740.034
regulation of cell cycle processGO:00105641600.034
regulation of stress activated mapk cascadeGO:0032872690.034
regulation of action potentialGO:009890040.034
posttranscriptional regulation of gene expressionGO:00106081550.034
nitrogen compound transportGO:00717052710.034
monosaccharide biosynthetic processGO:0046364440.034
regulation of lipid metabolic processGO:00192161180.033
positive regulation of killing of cells of other organismGO:005171230.033
cell activation involved in immune responseGO:00022631260.033
cellular response to cytokine stimulusGO:00713451890.033
Rat
cellular response to amino acid stimulusGO:0071230290.033
negative regulation of neuron projection regenerationGO:007057130.033
regulation of membrane protein ectodomain proteolysisGO:005104330.033
positive regulation of cysteine type endopeptidase activityGO:2001056390.033
regulation of removal of superoxide radicalsGO:200012140.033
homeostasis of number of cellsGO:00488722100.033
positive regulation of striated muscle cell differentiationGO:0051155350.033
regulation of blood circulationGO:1903522930.032
regulation of phospholipase activityGO:001051790.032
regulation of gliogenesisGO:0014013500.032
positive regulation of cell killingGO:0031343330.032
ceramide metabolic processGO:0006672310.032
vitellogenesisGO:000729620.032
forebrain developmentGO:00309003020.032
regulation of killing of cells of other organismGO:005170940.032
positive regulation of natural killer cell chemotaxisGO:200050310.032
organic anion transportGO:00157111370.032
response to interleukin 1GO:0070555110.032
Rat
negative regulation of protein processingGO:0010955790.032
dna metabolic processGO:00062593030.032
cellular chemical homeostasisGO:00550822150.032
Rat
positive regulation of cardiac muscle contractionGO:006045220.032
cellular ion homeostasisGO:00068731650.031
skeletal muscle fiber developmentGO:0048741580.031
cellular homeostasisGO:00197252400.031
Rat
leukocyte homeostasisGO:0001776790.031
glucose homeostasisGO:00425931280.031
Rat
neuron projection extensionGO:1990138640.031
regulation of purine nucleotide metabolic processGO:19005421690.031
fertilizationGO:00095661270.031
plasma membrane long chain fatty acid transportGO:001591110.031
nucleoside triphosphate metabolic processGO:00091412300.031
hindbrain developmentGO:00309021280.031
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.031
regulation of fibroblast proliferationGO:0048145340.031
Rat
response to alcoholGO:0097305480.031
Rat
positive regulation of protein deacetylationGO:009031290.030
nucleotide catabolic processGO:00091662170.030
t cell proliferationGO:00420981200.030
protein deacylationGO:0035601360.030
negative regulation of protein modification processGO:00314001630.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
membrane lipid metabolic processGO:0006643530.030
positive regulation of fibroblast proliferationGO:0048146200.030
Rat
regulation of protein kinase b signalingGO:0051896560.030
regulation of vasculature developmentGO:1901342880.030
cellular response to insulin stimulusGO:0032869780.030
Rat
cellular response to organonitrogen compoundGO:00714171450.030
Rat
response to drugGO:0042493750.030
Rat
hematopoietic progenitor cell differentiationGO:00022441430.030
axon guidanceGO:00074111410.030
sensory organ morphogenesisGO:00905962420.030
epithelial tube morphogenesisGO:00605623030.030
development of primary female sexual characteristicsGO:0046545730.029
Rat
positive regulation of organelle organizationGO:00106381280.029
epidermis developmentGO:00085441870.029
positive regulation of histone modificationGO:0031058280.029
positive regulation of neutrophil mediated killing of fungusGO:007096510.029
stem cell proliferationGO:00720891170.029
positive regulation of secretionGO:00510471300.029
negative regulation of macrophage apoptotic processGO:200011030.029
positive regulation of stress activated mapk cascadeGO:0032874480.029
positive regulation of protein transportGO:0051222930.029
glial cell differentiationGO:00100011310.029
positive regulation of cellular amine metabolic processGO:003324050.029
synapse organizationGO:00508081250.029
response to reactive oxygen speciesGO:0000302560.029
Rat
protein processingGO:00164851630.029
positive regulation of syncytium formation by plasma membrane fusionGO:0060143170.029
negative regulation of phosphate metabolic processGO:00459361840.029
sensory perceptionGO:00076002450.028
Mouse
regulation of wound healingGO:0061041400.028
positive regulation of wound healingGO:0090303170.028
Human
acetylcholine secretion neurotransmissionGO:001405520.028
glycosyl compound metabolic processGO:19016572460.028
membrane organizationGO:00610242450.028
natural killer cell chemotaxisGO:003574710.028
regulation of multi organism processGO:00439001110.028
macromolecule catabolic processGO:00090572810.028
Mouse
glucose metabolic processGO:0006006920.028
developmental maturationGO:00217001930.028
mitochondrion organizationGO:00070051340.028
positive regulation of muscle cell differentiationGO:0051149390.027
multi multicellular organism processGO:00447061090.027
Mouse Rat
macromolecule glycosylationGO:0043413550.027
tissue remodelingGO:00487711020.027
muscle fiber developmentGO:0048747760.027
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.027
regulation of skeletal muscle fiber developmentGO:0048742360.027
negative regulation of muscle cell differentiationGO:0051148330.027
response to estrogenGO:0043627240.027
Rat
female sex differentiationGO:0046660840.027
Rat
positive regulation of purine nucleotide metabolic processGO:19005441140.027
regulation of myeloid leukocyte differentiationGO:0002761580.027
regulation of plasminogen activationGO:001075540.027
heart processGO:0003015940.027
neuron deathGO:00709971540.027
regulation of osteoclast differentiationGO:0045670360.027
purine nucleoside catabolic processGO:00061522050.026
regionalizationGO:00030023370.026
regulation of vesicle mediated transportGO:00606271390.026
Human Rat
negative regulation of endothelial cell migrationGO:001059640.026
ear developmentGO:00435832000.026
regulation of cellular ketone metabolic processGO:0010565660.026
sequestering of metal ionGO:0051238190.026
mesoderm developmentGO:00074981000.026
regulation of b cell chemotaxisGO:200053720.026
positive regulation of homeostatic processGO:0032846640.026
neuron apoptotic processGO:00514021420.026
regulation of amine transportGO:0051952210.026
photoreceptor cell developmentGO:0042461400.026
cellular response to acid chemicalGO:0071229680.026
hexose biosynthetic processGO:0019319390.026
ameboidal type cell migrationGO:00016671280.026
Rat
response to corticosteroidGO:0031960200.026
Rat
peptidyl lysine modificationGO:0018205770.025
embryonic organ morphogenesisGO:00485622760.025
positive regulation of t cell activationGO:00508701010.025
hormone secretionGO:00468791280.025
protein localization to cell junctionGO:190241430.025
germ cell developmentGO:00072811850.025
regulation of ion transportGO:00432692150.025
Mouse Rat
ribose phosphate metabolic processGO:00196932910.025
positive regulation of protein kinase b signalingGO:0051897320.025
positive regulation of neuron projection developmentGO:0010976790.025
regulation of neurotransmitter transportGO:0051588350.025
positive regulation of leukocyte mediated immunityGO:0002705700.025
positive regulation of defense responseGO:00313491240.024
Human
positive regulation of secretion by cellGO:19035321140.024
regulation of stem cell differentiationGO:2000736500.024

Serpine1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.145
disease of anatomical entityDOID:700.145
sensory system diseaseDOID:005015500.052
neuropathyDOID:87000.052
neuromuscular diseaseDOID:44000.052
disease of metabolismDOID:001466700.036
charcot marie tooth diseaseDOID:1059500.032
eye and adnexa diseaseDOID:149200.031
acquired metabolic diseaseDOID:006015800.025