Mus musculus

125 known processes

Trps1

trichorhinophalangeal syndrome I (human)

(Aliases: D15Ertd586e,AI447310,AI115454,MGC46754,MGC107472)

Trps1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal system developmentGO:00015013560.108
regulation of cellular amino acid metabolic processGO:000652150.107
regulation of cellular amine metabolic processGO:0033238200.091
lymphocyte differentiationGO:00300982420.091
regulation of cellular ketone metabolic processGO:0010565660.090
mapk cascadeGO:00001652810.090
cellular amine metabolic processGO:0044106440.082
positive regulation of protein modification processGO:00314012990.077
cellular amino acid metabolic processGO:00065201030.076
kidney developmentGO:00018222130.074
regulation of organelle organizationGO:00330432890.073
renal system developmentGO:00720012250.071
myeloid cell differentiationGO:00300992330.071
regulation of cell migrationGO:00303342190.067
gland developmentGO:00487323300.066
amine metabolic processGO:0009308450.065
bone developmentGO:00603481200.062
positive regulation of cellular amine metabolic processGO:003324050.059
regulation of mapk cascadeGO:00434082480.057
urogenital system developmentGO:00016552610.055
endocytosisGO:00068971680.055
positive regulation of apoptotic processGO:00430652170.053
leukocyte differentiationGO:00025213420.053
chromatin organizationGO:00063252060.052
negative regulation of molecular functionGO:00440922580.050
skeletal system morphogenesisGO:00487052030.050
chromatin modificationGO:00165681870.048
cellular ketone metabolic processGO:0042180840.048
embryonic organ morphogenesisGO:00485622760.047
regulation of neuron differentiationGO:00456642810.046
sensory organ morphogenesisGO:00905962420.044
negative regulation of cellular amine metabolic processGO:003323910.044
muscle cell differentiationGO:00426922610.044
regulation of vesicle mediated transportGO:00606271390.043
forebrain developmentGO:00309003020.043
heterocycle catabolic processGO:00467002800.043
neural tube developmentGO:00219151600.042
transmembrane transportGO:00550854120.042
response to growth factorGO:00708481980.041
positive regulation of transferase activityGO:00513471670.041
cartilage developmentGO:00512161400.041
negative regulation of cellular component organizationGO:00511291940.041
camera type eye developmentGO:00430102660.040
stem cell developmentGO:00488642190.040
regionalizationGO:00030023370.040
macromolecule catabolic processGO:00090572810.039
epithelial tube morphogenesisGO:00605623030.039
positive regulation of cellular amino acid metabolic processGO:004576430.038
oxidation reduction processGO:00551143420.038
regulation of synaptic growth at neuromuscular junctionGO:000858240.038
lateral inhibitionGO:004633110.038
negative regulation of cell developmentGO:00107211690.038
small gtpase mediated signal transductionGO:0007264970.038
negative regulation of nervous system developmentGO:00519611560.037
nucleoside metabolic processGO:00091162460.036
negative regulation of cellular protein metabolic processGO:00322692470.036
negative regulation of cellular amino acid metabolic processGO:004576300.036
purine nucleoside triphosphate metabolic processGO:00091442260.036
embryonic epithelial tube formationGO:00018381300.035
aromatic compound catabolic processGO:00194392860.035
digestive tract developmentGO:00485651900.035
positive regulation of growthGO:00459271040.034
multicellular organismal signalingGO:0035637910.034
ribonucleoside metabolic processGO:00091192450.034
immune effector processGO:00022523210.033
primary neural tube formationGO:0014020950.033
purine ribonucleoside metabolic processGO:00461282410.033
regulation of cytoskeleton organizationGO:00514931220.033
regulation of secretion by cellGO:19035302490.032
fat cell differentiationGO:00454441600.032
positive regulation of nervous system developmentGO:00519622210.032
central nervous system neuron differentiationGO:00219531620.032
purine ribonucleoside triphosphate catabolic processGO:00092071990.031
neuronal action potentialGO:0019228540.031
positive regulation of cell activationGO:00508671580.031
membrane organizationGO:00610242450.031
ossificationGO:00015032160.031
organelle fissionGO:00482851700.030
nucleobase containing small molecule metabolic processGO:00550863520.030
axon guidanceGO:00074111410.030
regulation of cell motilityGO:20001452360.030
action potentialGO:0001508780.030
regulation of protein kinase activityGO:00458592320.030
dna metabolic processGO:00062593030.030
purine containing compound metabolic processGO:00725213110.030
carbohydrate metabolic processGO:00059752300.030
regulation of lymphocyte activationGO:00512492400.029
protein modification by small protein conjugation or removalGO:00706472070.029
limb developmentGO:00601731660.029
nucleoside triphosphate metabolic processGO:00091412300.029
positive regulation of protein kinase activityGO:00458601440.029
digestive system developmentGO:00551232000.029
male gamete generationGO:00482322850.028
neural tube formationGO:00018411080.028
ribonucleoside triphosphate catabolic processGO:00092031990.027
regulation of membrane potentialGO:00423911920.027
blood vessel morphogenesisGO:00485142850.027
peptide secretionGO:00027901140.027
inorganic cation transmembrane transportGO:00986622070.027
nucleoside phosphate catabolic processGO:19012922220.026
regulation of transferase activityGO:00513382630.026
purine nucleoside catabolic processGO:00061522050.026
gliogenesisGO:00420631410.026
muscle tissue developmentGO:00605373080.026
nucleotide metabolic processGO:00091173320.026
regulation of actin cytoskeleton organizationGO:0032956840.026
positive regulation of lymphocyte activationGO:00512511400.026
positive regulation of neuron differentiationGO:00456661410.026
positive regulation of mapk cascadeGO:00434101700.026
cell type specific apoptotic processGO:00972852680.025
cellular macromolecule catabolic processGO:00442652060.025
regulation of cell projection organizationGO:00313442060.025
purine nucleoside metabolic processGO:00422782410.025
striated muscle tissue developmentGO:00147062930.025
positive regulation of kinase activityGO:00336741550.025
sensory perceptionGO:00076002450.025
nucleoside catabolic processGO:00091642060.025
negative regulation of intracellular signal transductionGO:19025321670.025
regulation of actin filament based processGO:0032970990.025
cellular response to growth factor stimulusGO:00713631970.025
regulation of anatomical structure sizeGO:00900661780.025
embryonic skeletal system developmentGO:00487061200.025
midgut developmentGO:000749440.025
glial cell differentiationGO:00100011310.024
connective tissue developmentGO:00614481790.024
protein ubiquitinationGO:00165671710.024
purine nucleotide catabolic processGO:00061952110.024
negative regulation of cell proliferationGO:00082852960.024
skin developmentGO:00435882200.024
segmentationGO:0035282930.024
cellular response to organonitrogen compoundGO:00714171450.024
t cell differentiationGO:00302171740.024
bone morphogenesisGO:0060349780.024
actin cytoskeleton organizationGO:00300362200.024
neuron deathGO:00709971540.024
positive regulation of protein phosphorylationGO:00019342420.024
protein catabolic processGO:00301632210.024
germ cell developmentGO:00072811850.023
positive regulation of programmed cell deathGO:00430682180.023
chemotaxisGO:00069352470.023
mitochondrion organizationGO:00070051340.023
placenta developmentGO:00018901400.023
regulation of secretionGO:00510462740.023
regulation of cellular component biogenesisGO:00440871810.023
response to organonitrogen compoundGO:00102432460.023
ear developmentGO:00435832000.023
organic cyclic compound catabolic processGO:19013612950.023
peptidyl lysine modificationGO:0018205770.023
regulation of bindingGO:00510981110.022
negative regulation of protein modification processGO:00314001630.022
epidermis developmentGO:00085441870.022
nucleoside phosphate metabolic processGO:00067533380.022
neuron migrationGO:00017641220.022
purine ribonucleotide catabolic processGO:00091542080.022
ribose phosphate metabolic processGO:00196932910.022
covalent chromatin modificationGO:00165691630.022
tube formationGO:00351481400.022
cation transmembrane transportGO:00986552660.022
cognitionGO:00508901490.022
rho protein signal transductionGO:0007266320.022
appendage morphogenesisGO:00351071490.022
response to extracellular stimulusGO:00099911270.022
mesenchymal cell differentiationGO:00487621070.022
purine ribonucleotide metabolic processGO:00091502900.022
organonitrogen compound catabolic processGO:19015652640.022
skeletal muscle organ developmentGO:00605381630.022
regulation of feeding behaviorGO:006025930.022
positive regulation of cell deathGO:00109422240.022
angiogenesisGO:00015252010.021
t cell activationGO:00421102890.021
protein methylationGO:0006479810.021
microtubule cytoskeleton organizationGO:00002261570.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
ras protein signal transductionGO:0007265770.021
inorganic ion transmembrane transportGO:00986602340.021
central nervous system neuron developmentGO:0021954670.021
positive regulation of hydrolase activityGO:00513451480.021
regulation of system processGO:00440572000.021
regulation of cellular catabolic processGO:00313292420.021
alpha beta t cell activationGO:0046631910.021
ribonucleotide catabolic processGO:00092612080.021
ribonucleoside catabolic processGO:00424542060.021
epithelial tube formationGO:00721751300.021
protein acylationGO:0043543640.021
response to organic cyclic compoundGO:00140701980.020
regulation of response to woundingGO:19030341890.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
carbohydrate derivative catabolic processGO:19011362310.020
microtubule based processGO:00070172360.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
maintenance of locationGO:0051235890.020
response to inorganic substanceGO:0010035960.020
morphogenesis of embryonic epitheliumGO:00163311590.020
cellular response to hormone stimulusGO:00328701500.020
respiratory system developmentGO:00605411900.020
histone modificationGO:00165701590.020
neuron projection guidanceGO:00974851410.019
mrna processingGO:0006397630.019
protein modification by small protein conjugationGO:00324461870.019
regulation of cell activationGO:00508652890.019
learning or memoryGO:00076111480.019
protein polymerizationGO:0051258570.019
transmission of nerve impulseGO:0019226760.019
mesenchyme developmentGO:00604851520.019
glycosyl compound catabolic processGO:19016582060.019
response to transforming growth factor betaGO:0071559880.019
stem cell differentiationGO:00488632680.019
negative regulation of protein metabolic processGO:00512482820.019
negative regulation of growthGO:0045926990.019
developmental maturationGO:00217001930.019
alpha beta t cell differentiationGO:0046632690.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
purine nucleotide metabolic processGO:00061633020.019
carbohydrate homeostasisGO:00335001280.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.018
cell fate commitmentGO:00451652100.018
axon ensheathmentGO:0008366760.018
development of primary sexual characteristicsGO:00451371430.018
organelle assemblyGO:00709251770.018
epithelial cell developmentGO:00020641590.018
neural tube closureGO:0001843900.018
telencephalon developmentGO:00215371860.018
regulation of cellular response to stressGO:00801351590.018
cellular response to transforming growth factor beta stimulusGO:0071560880.018
embryonic appendage morphogenesisGO:00351131260.018
regulation of ossificationGO:00302781120.018
multicellular organism growthGO:00352641610.018
histone methylationGO:0016571710.018
photoreceptor cell differentiationGO:0046530520.018
regulation of kinase activityGO:00435492490.018
inflammatory responseGO:00069542440.018
positive regulation of jnk cascadeGO:0046330460.018
organophosphate catabolic processGO:00464342320.018
regulation of nucleoside metabolic processGO:00091181300.018
regulation of apoptotic signaling pathwayGO:20012331970.018
response to acid chemicalGO:00011011110.018
nucleoside triphosphate catabolic processGO:00091432050.018
regulation of hydrolase activityGO:00513362460.018
methylationGO:00322591340.017
innate immune responseGO:00450871570.017
respiratory tube developmentGO:00303231670.017
hormone secretionGO:00468791280.017
ear morphogenesisGO:00424711180.017
nitrogen compound transportGO:00717052710.017
purine containing compound catabolic processGO:00725232130.017
locomotory behaviorGO:00076261950.017
developmental growth involved in morphogenesisGO:00605601380.017
vesicle organizationGO:0016050600.017
myelinationGO:0042552740.017
lipid biosynthetic processGO:00086101790.017
morphogenesis of a branching structureGO:00017632030.017
kidney epithelium developmentGO:00720731210.017
positive regulation of purine nucleotide metabolic processGO:19005441140.017
ribonucleotide metabolic processGO:00092592910.017
g protein coupled receptor signaling pathwayGO:00071862430.017
cytoplasmic transportGO:00164822340.017
peptidyl amino acid modificationGO:00181933360.017
spermatid differentiationGO:00485151150.017
multi multicellular organism processGO:00447061090.017
morphogenesis of a branching epitheliumGO:00611381930.017
regulation of multi organism processGO:00439001110.016
cellular protein complex assemblyGO:00436231160.016
response to nutrient levelsGO:00316671090.016
branching morphogenesis of an epithelial tubeGO:00487541590.016
tube closureGO:0060606910.016
regulation of body fluid levelsGO:00508781620.016
nucleotide catabolic processGO:00091662170.016
myeloid leukocyte differentiationGO:00025731190.016
dephosphorylationGO:00163111290.016
reactive oxygen species metabolic processGO:0072593840.016
b cell differentiationGO:0030183780.016
regulation of sequence specific dna binding transcription factor activityGO:00510901060.016
axonogenesisGO:00074092740.016
cell adhesionGO:00071553290.016
hematopoietic progenitor cell differentiationGO:00022441430.016
positive regulation of endocytosisGO:0045807420.016
regulation of hormone levelsGO:00108172110.016
cell migration involved in gastrulationGO:0042074130.015
amide transportGO:00428861380.015
cellular response to molecule of bacterial originGO:0071219830.015
neuron apoptotic processGO:00514021420.015
b cell activationGO:00421131610.015
regulation of proteolysisGO:00301621640.015
somite developmentGO:0061053810.015
learningGO:0007612980.015
multi organism behaviorGO:0051705620.015
leukocyte activation involved in immune responseGO:00023661260.015
regulation of cellular response to growth factor stimulusGO:0090287820.015
biomineral tissue developmentGO:0031214640.015
regulation of establishment of protein localizationGO:00702011810.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
organelle localizationGO:00516401790.015
nuclear divisionGO:00002801580.015
cellular ion homeostasisGO:00068731650.015
spermatogenesisGO:00072832840.015
compound eye developmentGO:004874910.015
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.015
apoptotic signaling pathwayGO:00971903060.015
organic hydroxy compound metabolic processGO:19016152030.015
regulation of nucleotide metabolic processGO:00061401690.015
protein maturationGO:00516041760.015
stress activated mapk cascadeGO:0051403800.015
negative regulation of protein maturationGO:1903318790.015
establishment of vesicle localizationGO:0051650810.015
cellular response to acid chemicalGO:0071229680.015
gtp metabolic processGO:00460391440.015
response to lipopolysaccharideGO:00324961280.014
skeletal muscle cell differentiationGO:0035914660.014
actin filament organizationGO:00070151130.014
cation transportGO:00068123990.014
activation of immune responseGO:00022531380.014
fertilizationGO:00095661270.014
regulation of cell adhesionGO:00301551540.014
embryonic limb morphogenesisGO:00303261260.014
cellular response to external stimulusGO:0071496880.014
regulation of leukocyte differentiationGO:19021051590.014
cellular response to lipidGO:00713961450.014
negative regulation of ossificationGO:0030279490.014
glycosyl compound metabolic processGO:19016572460.014
photoreceptor cell developmentGO:0042461400.014
regulation of protein processingGO:0070613960.014
response to corticosteroneGO:005141210.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
cerebral cortex developmentGO:0021987860.014
endomembrane system organizationGO:00102561470.014
response to peptideGO:19016521360.014
protein alkylationGO:0008213810.014
organ growthGO:00352651170.014
leukocyte migrationGO:00509001240.014
regulation of ras protein signal transductionGO:00465781140.014
actin mediated cell contractionGO:0070252150.014
determination of left right symmetryGO:0007368800.014
cytokinetic processGO:003250620.014
dendrite developmentGO:00163581150.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
regulation of fat cell differentiationGO:0045598810.014
defense response to other organismGO:00985421970.014
establishment of organelle localizationGO:00516561220.014
gonad developmentGO:00084061410.013
somitogenesisGO:0001756690.013
regulation of defense responseGO:00313472330.013
regulation of map kinase activityGO:00434051200.013
stress activated protein kinase signaling cascadeGO:0031098810.013
carbohydrate derivative biosynthetic processGO:19011371830.013
regulation of lymphocyte differentiationGO:00456191070.013
regulation of protein complex assemblyGO:0043254830.013
cellular response to cytokine stimulusGO:00713451890.013
synapse organizationGO:00508081250.013
positive regulation of leukocyte proliferationGO:0070665730.013
pharynx developmentGO:006046510.013
peptide transportGO:00158331330.013
positive regulation of apoptotic signaling pathwayGO:2001235950.013
cellular chemical homeostasisGO:00550822150.013
guanosine containing compound catabolic processGO:19010691440.013
lipid localizationGO:00108761260.013
chondrocyte differentiationGO:0002062720.013
response to peptide hormoneGO:00434341270.013
limb morphogenesisGO:00351081490.013
spermatid developmentGO:00072861080.013
regulation of endocytosisGO:0030100690.013
palate developmentGO:0060021760.013
tissue remodelingGO:00487711020.013
peptidyl tyrosine modificationGO:00182121450.013
intracellular protein transportGO:00068862040.013
response to light stimulusGO:00094161350.013
actin filament based movementGO:0030048230.013
exocytosisGO:00068871210.013
endochondral bone morphogenesisGO:0060350500.013
regulation of protein catabolic processGO:00421761080.013
anatomical structure maturationGO:0071695490.013
protein localization to organelleGO:00333651850.013
regulation of neuron projection developmentGO:00109751690.013
appendage developmentGO:00487361660.013
stem cell maintenanceGO:00198271300.013
wnt signaling pathwayGO:00160551880.013
negative regulation of epithelial cell proliferationGO:0050680640.013
actin polymerization or depolymerizationGO:0008154540.013
posttranscriptional regulation of gene expressionGO:00106081550.013
negative regulation of neuron deathGO:1901215980.013
adult behaviorGO:00305341350.013
syncytium formation by plasma membrane fusionGO:0000768420.013
determination of heart left right asymmetryGO:0061371480.013
monocarboxylic acid metabolic processGO:00327871910.013
gtp catabolic processGO:00061841430.013
lung developmentGO:00303241640.012
regulation of myeloid cell differentiationGO:0045637960.012
ensheathment of neuronsGO:0007272760.012
response to radiationGO:00093141650.012
cellular carbohydrate metabolic processGO:00442621190.012
cellular homeostasisGO:00197252400.012
adaptive immune responseGO:00022501550.012
asymmetric stem cell divisionGO:009872230.012
nephron developmentGO:00720061090.012
cellular component assembly involved in morphogenesisGO:00109271390.012
protein processingGO:00164851630.012
female gamete generationGO:0007292740.012
inner ear morphogenesisGO:00424721010.012
blastocyst developmentGO:0001824800.012
proteasomal protein catabolic processGO:0010498980.012
pallium developmentGO:00215431200.012
cell divisionGO:00513011200.012
motor neuron axon guidanceGO:0008045260.012
glucose homeostasisGO:00425931280.012
forebrain cell migrationGO:0021885580.012
retina development in camera type eyeGO:00600411190.012
regulation of rho protein signal transductionGO:0035023710.012
positive regulation of map kinase activityGO:0043406840.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
male sex differentiationGO:00466611090.012
cellular lipid metabolic processGO:00442553230.012
canonical wnt signaling pathwayGO:00600701300.012
negative regulation of cell migrationGO:0030336590.012
digestive tract morphogenesisGO:00485461470.012
gastrulationGO:00073691160.012
regulation of organ growthGO:0046620610.012
homeostasis of number of cellsGO:00488722100.012
embryonic skeletal system morphogenesisGO:0048704910.012
bone mineralizationGO:0030282540.012
myosin filament assemblyGO:003103420.012
regulation of homeostatic processGO:00328441820.012
smoothened signaling pathwayGO:00072241050.012
cell substrate adhesionGO:00315891300.012
regulation of osteoblast differentiationGO:0045667670.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
cation homeostasisGO:00550802120.012
cellular response to abiotic stimulusGO:0071214560.012
eosinophil migrationGO:007267730.011
tissue homeostasisGO:00018941150.011
regulation of canonical wnt signaling pathwayGO:0060828820.011
vesicle localizationGO:0051648860.011
negative regulation of phosphate metabolic processGO:00459361840.011
negative regulation of neuron differentiationGO:00456651010.011
response to molecule of bacterial originGO:00022371430.011
positive regulation of cellular component biogenesisGO:0044089940.011
single organism cell adhesionGO:00986021560.011
substantia nigra developmentGO:002176220.011
nerve developmentGO:0021675670.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
regulation of t cell activationGO:00508631700.011
peptidyl tyrosine phosphorylationGO:00181081430.011
glycoprotein metabolic processGO:00091001160.011
positive regulation of cell motilityGO:20001471160.011
response to parathyroid hormoneGO:007110730.011
regulation of neuron deathGO:19012141340.011
negative regulation of protein phosphorylationGO:00019331260.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
negative regulation of proteolysisGO:0045861740.011
embryonic placenta developmentGO:0001892980.011
epithelial cell proliferationGO:00506731740.011
cell activation involved in immune responseGO:00022631260.011
glial cell developmentGO:0021782540.011
body morphogenesisGO:0010171450.011
mitotic cell cycleGO:00002781950.011
bmp signaling pathwayGO:0030509930.011
response to amino acidGO:0043200370.011
oogenesisGO:0048477560.011
eye photoreceptor cell differentiationGO:0001754410.011
regulation of purine nucleotide metabolic processGO:19005421690.011
regulation of cellular component sizeGO:00325351210.011
negative regulation of immune system processGO:00026832090.011
regulation of protein serine threonine kinase activityGO:00719001570.011
myotube differentiationGO:00149021050.011
regulation of embryonic developmentGO:0045995710.011
lymphocyte mediated immunityGO:00024491390.011
mitotic cytokinesisGO:000028140.011
regulation of wnt signaling pathwayGO:00301111230.011
regulation of protein maturationGO:1903317960.011
myeloid cell homeostasisGO:00022621140.011
cellular protein catabolic processGO:00442571550.011
myoblast differentiationGO:0045445520.011
cellular response to organic cyclic compoundGO:0071407870.011
glycoprotein biosynthetic processGO:0009101890.011
clara cell differentiationGO:006048640.011
actin filament polymerizationGO:0030041440.011
lymphocyte proliferationGO:00466511640.011
regulation of muscle tissue developmentGO:1901861970.011
cellular response to biotic stimulusGO:0071216920.011
ion transmembrane transportGO:00342203610.011
positive regulation of gtp catabolic processGO:0033126850.010
embryonic heart tube morphogenesisGO:0003143510.010
negative regulation of phosphorylationGO:00423261660.010
positive regulation of apoptotic cell clearanceGO:200042730.010
engulfment of apoptotic cellGO:004365230.010
positive regulation of nucleotide metabolic processGO:00459811140.010
retina morphogenesis in camera type eyeGO:0060042450.010
forebrain generation of neuronsGO:0021872630.010
defense response to bacteriumGO:00427421190.010

Trps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
organ system cancerDOID:005068600.014
disease of metabolismDOID:001466700.013
central nervous system diseaseDOID:33100.010
neurodegenerative diseaseDOID:128900.010