Mus musculus

19 known processes

Aff3

AF4/FMR2 family, member 3

(Aliases: Laf4,LAF-4,3222402O04Rik,A730046J16)

Aff3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238200.063
purine ribonucleotide metabolic processGO:00091502900.062
male gamete generationGO:00482322850.061
ras protein signal transductionGO:0007265770.060
cellular ketone metabolic processGO:0042180840.059
regulation of cellular amino acid metabolic processGO:000652150.058
cell adhesionGO:00071553290.056
small gtpase mediated signal transductionGO:0007264970.056
regulation of cellular ketone metabolic processGO:0010565660.055
nucleotide metabolic processGO:00091173320.055
purine nucleotide metabolic processGO:00061633020.052
cellular amino acid metabolic processGO:00065201030.051
nucleobase containing small molecule metabolic processGO:00550863520.049
chromatin organizationGO:00063252060.048
aromatic compound catabolic processGO:00194392860.046
purine containing compound metabolic processGO:00725213110.045
positive regulation of cellular catabolic processGO:00313311480.043
glycosyl compound catabolic processGO:19016582060.043
ribonucleotide metabolic processGO:00092592910.042
macromolecule methylationGO:00434141200.042
regulation of cell activationGO:00508652890.042
actin cytoskeleton organizationGO:00300362200.042
nucleoside phosphate metabolic processGO:00067533380.042
purine ribonucleoside metabolic processGO:00461282410.041
peptidyl amino acid modificationGO:00181933360.041
positive regulation of cellular amine metabolic processGO:003324050.041
heterocycle catabolic processGO:00467002800.039
immune effector processGO:00022523210.039
organonitrogen compound catabolic processGO:19015652640.039
regulation of cellular catabolic processGO:00313292420.039
regulation of organelle organizationGO:00330432890.038
carbohydrate derivative catabolic processGO:19011362310.038
purine nucleoside catabolic processGO:00061522050.037
nucleoside catabolic processGO:00091642060.036
nucleoside metabolic processGO:00091162460.036
mapk cascadeGO:00001652810.035
positive regulation of gtp catabolic processGO:0033126850.035
ribose phosphate metabolic processGO:00196932910.035
cellular nitrogen compound catabolic processGO:00442702800.035
purine nucleoside triphosphate catabolic processGO:00091462030.034
spermatogenesisGO:00072832840.034
histone modificationGO:00165701590.033
purine nucleotide catabolic processGO:00061952110.033
ribonucleoside catabolic processGO:00424542060.033
amine metabolic processGO:0009308450.032
methylationGO:00322591340.032
regulation of cellular component biogenesisGO:00440871810.031
regulation of mapk cascadeGO:00434082480.031
cellular homeostasisGO:00197252400.031
purine ribonucleoside catabolic processGO:00461302050.031
ribonucleoside triphosphate metabolic processGO:00091992200.030
skeletal system developmentGO:00015013560.030
organic cyclic compound catabolic processGO:19013612950.030
cellular amine metabolic processGO:0044106440.030
negative regulation of immune system processGO:00026832090.030
leukocyte differentiationGO:00025213420.030
nucleotide catabolic processGO:00091662170.030
negative regulation of cell proliferationGO:00082852960.030
purine nucleoside metabolic processGO:00422782410.029
glycosyl compound metabolic processGO:19016572460.029
protein methylationGO:0006479810.029
ribonucleoside metabolic processGO:00091192450.029
protein alkylationGO:0008213810.029
nucleoside triphosphate catabolic processGO:00091432050.029
regulation of purine nucleotide metabolic processGO:19005421690.029
organophosphate catabolic processGO:00464342320.029
histone methylationGO:0016571710.029
lymphocyte differentiationGO:00300982420.028
negative regulation of cellular component organizationGO:00511291940.028
gtp catabolic processGO:00061841430.028
purine containing compound catabolic processGO:00725232130.028
nucleoside triphosphate metabolic processGO:00091412300.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
axonogenesisGO:00074092740.027
negative regulation of phosphorus metabolic processGO:00105631840.027
macromolecule catabolic processGO:00090572810.027
regulation of transferase activityGO:00513382630.027
regionalizationGO:00030023370.027
cellular response to lipidGO:00713961450.026
rho protein signal transductionGO:0007266320.026
purine ribonucleotide catabolic processGO:00091542080.026
guanosine containing compound catabolic processGO:19010691440.026
ribonucleotide catabolic processGO:00092612080.026
regulation of secretionGO:00510462740.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.026
t cell activationGO:00421102890.026
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
regulation of lymphocyte activationGO:00512492400.026
muscle cell differentiationGO:00426922610.025
cellular chemical homeostasisGO:00550822150.025
regulation of gtp catabolic processGO:00331241130.025
gtp metabolic processGO:00460391440.025
positive regulation of purine nucleotide metabolic processGO:19005441140.024
regulation of nucleoside metabolic processGO:00091181300.024
carbohydrate metabolic processGO:00059752300.024
homeostasis of number of cellsGO:00488722100.024
regulation of nucleotide catabolic processGO:00308111220.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
purine ribonucleoside triphosphate catabolic processGO:00092071990.024
nitrogen compound transportGO:00717052710.023
asymmetric stem cell divisionGO:009872230.023
regulation of cell cycleGO:00517262810.023
negative regulation of molecular functionGO:00440922580.023
forebrain developmentGO:00309003020.023
regulation of protein kinase activityGO:00458592320.023
cellular lipid metabolic processGO:00442553230.023
regulation of purine nucleotide catabolic processGO:00331211220.023
g protein coupled receptor signaling pathwayGO:00071862430.023
chromatin modificationGO:00165681870.023
covalent chromatin modificationGO:00165691630.022
regulation of neuron differentiationGO:00456642810.022
carbohydrate derivative biosynthetic processGO:19011371830.022
wnt signaling pathwayGO:00160551880.022
positive regulation of nucleoside metabolic processGO:0045979910.022
protein modification by small protein conjugation or removalGO:00706472070.022
nucleoside phosphate catabolic processGO:19012922220.022
multicellular organismal signalingGO:0035637910.022
positive regulation of protein modification processGO:00314012990.022
regulation of secretion by cellGO:19035302490.022
apoptotic signaling pathwayGO:00971903060.022
actin filament organizationGO:00070151130.021
regulation of nucleotide metabolic processGO:00061401690.021
camera type eye developmentGO:00430102660.021
gland developmentGO:00487323300.021
regulation of hydrolase activityGO:00513362460.021
negative regulation of intracellular signal transductionGO:19025321670.021
positive regulation of organelle organizationGO:00106381280.021
ossificationGO:00015032160.021
regulation of hormone levelsGO:00108172110.021
response to organonitrogen compoundGO:00102432460.021
positive regulation of nucleotide catabolic processGO:0030813880.021
regulation of ras protein signal transductionGO:00465781140.021
negative regulation of protein phosphorylationGO:00019331260.020
negative regulation of protein modification processGO:00314001630.020
cytoplasmic transportGO:00164822340.020
amide transportGO:00428861380.020
cellular metal ion homeostasisGO:00068751510.020
protein ubiquitinationGO:00165671710.020
protein catabolic processGO:00301632210.020
negative regulation of phosphate metabolic processGO:00459361840.020
response to lipopolysaccharideGO:00324961280.020
positive regulation of cell developmentGO:00107202370.020
negative regulation of phosphorylationGO:00423261660.020
cellular response to organonitrogen compoundGO:00714171450.020
regulation of intracellular transportGO:00323861590.020
stem cell differentiationGO:00488632680.019
positive regulation of nucleotide metabolic processGO:00459811140.019
membrane organizationGO:00610242450.019
regulation of synaptic growth at neuromuscular junctionGO:000858240.019
epithelial tube morphogenesisGO:00605623030.019
cytokine productionGO:00018163190.019
positive regulation of purine nucleotide catabolic processGO:0033123880.019
organonitrogen compound biosynthetic processGO:19015661920.019
muscle system processGO:00030121410.019
negative regulation of protein metabolic processGO:00512482820.019
dna metabolic processGO:00062593030.019
microtubule based processGO:00070172360.019
compound eye developmentGO:004874910.019
negative regulation of cellular protein metabolic processGO:00322692470.019
response to organic cyclic compoundGO:00140701980.019
positive regulation of secretionGO:00510471300.019
protein modification by small protein conjugationGO:00324461870.019
endocytosisGO:00068971680.019
respiratory tube developmentGO:00303231670.019
multicellular organism growthGO:00352641610.019
cation homeostasisGO:00550802120.019
skin developmentGO:00435882200.019
histone lysine methylationGO:0034968500.019
regulation of actin filament based processGO:0032970990.019
cellular macromolecule catabolic processGO:00442652060.019
leukocyte proliferationGO:00706611720.018
regulation of system processGO:00440572000.018
regulation of kinase activityGO:00435492490.018
regulation of neuron projection developmentGO:00109751690.018
regulation of protein localizationGO:00328802310.018
telencephalon developmentGO:00215371860.018
regulation of protein serine threonine kinase activityGO:00719001570.018
inflammatory responseGO:00069542440.018
regulation of homeostatic processGO:00328441820.018
negative regulation of nervous system developmentGO:00519611560.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.018
cellular response to cytokine stimulusGO:00713451890.018
t cell differentiationGO:00302171740.018
regulation of bindingGO:00510981110.018
regulation of chromosome organizationGO:0033044830.018
transmembrane transportGO:00550854120.018
myeloid cell differentiationGO:00300992330.018
guanosine containing compound metabolic processGO:19010681440.018
metal ion homeostasisGO:00550651890.017
positive regulation of hydrolase activityGO:00513451480.017
sensory organ morphogenesisGO:00905962420.017
oxidation reduction processGO:00551143420.017
regulation of peptide transportGO:0090087910.017
regulation of chromatin modificationGO:1903308570.017
morphogenesis of embryonic epitheliumGO:00163311590.017
striated muscle tissue developmentGO:00147062930.017
cell type specific apoptotic processGO:00972852680.017
regulation of anatomical structure sizeGO:00900661780.017
hormone secretionGO:00468791280.017
negative regulation of transferase activityGO:0051348850.017
positive regulation of protein phosphorylationGO:00019342420.017
positive regulation of nervous system developmentGO:00519622210.017
protein localization to organelleGO:00333651850.017
negative regulation of cell developmentGO:00107211690.017
peptide hormone secretionGO:00300721090.017
response to molecule of bacterial originGO:00022371430.017
cellular response to hormone stimulusGO:00328701500.016
innate immune responseGO:00450871570.016
lymphocyte proliferationGO:00466511640.016
muscle tissue developmentGO:00605373080.016
glucose homeostasisGO:00425931280.016
regulation of membrane potentialGO:00423911920.016
fat cell differentiationGO:00454441600.016
skeletal muscle organ developmentGO:00605381630.016
protein polymerizationGO:0051258570.016
regulation of ras gtpase activityGO:0032318880.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
sequestering of metal ionGO:0051238190.016
positive regulation of mapk cascadeGO:00434101700.016
neural tube developmentGO:00219151600.016
b cell activationGO:00421131610.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of cytokine productionGO:00018172660.016
regulation of cellular component sizeGO:00325351210.016
regulation of leukocyte differentiationGO:19021051590.016
peptide secretionGO:00027901140.015
cilium morphogenesisGO:00602711020.015
transmission of nerve impulseGO:0019226760.015
calcium ion homeostasisGO:00550741270.015
cognitionGO:00508901490.015
peptide transportGO:00158331330.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
cation transportGO:00068123990.015
cellular ion homeostasisGO:00068731650.015
regulation of defense responseGO:00313472330.015
intracellular protein transportGO:00068862040.015
positive regulation of transferase activityGO:00513471670.015
divalent inorganic cation homeostasisGO:00725071380.015
rap protein signal transductionGO:003248630.015
monocarboxylic acid metabolic processGO:00327871910.015
insulin secretionGO:0030073890.015
actin polymerization or depolymerizationGO:0008154540.015
cellular response to dna damage stimulusGO:00069742070.015
respiratory system developmentGO:00605411900.015
regulation of response to woundingGO:19030341890.015
divalent inorganic cation transportGO:00725111780.015
cellular response to growth factor stimulusGO:00713631970.015
cellular protein complex assemblyGO:00436231160.015
regulation of vesicle mediated transportGO:00606271390.015
actin filament polymerizationGO:0030041440.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
regulation of apoptotic signaling pathwayGO:20012331970.014
cellular component assembly involved in morphogenesisGO:00109271390.014
establishment of protein localization to organelleGO:00725941180.014
inorganic ion transmembrane transportGO:00986602340.014
negative regulation of cellular amine metabolic processGO:003323910.014
negative regulation of cell cycleGO:00457861230.014
ubiquitin dependent protein catabolic processGO:00065111290.014
regulation of t cell activationGO:00508631700.014
regulation of establishment of protein localizationGO:00702011810.014
regulation of actin cytoskeleton organizationGO:0032956840.014
spermatid differentiationGO:00485151150.014
positive regulation of cell activationGO:00508671580.014
positive regulation of lymphocyte activationGO:00512511400.014
protein maturationGO:00516041760.014
positive regulation of gtpase activityGO:0043547850.014
negative regulation of growthGO:0045926990.014
placenta developmentGO:00018901400.014
organelle fissionGO:00482851700.014
organelle assemblyGO:00709251770.014
positive regulation of cell deathGO:00109422240.014
negative regulation of organelle organizationGO:0010639900.014
cell divisionGO:00513011200.014
blood vessel morphogenesisGO:00485142850.014
circulatory system processGO:00030131970.014
cation transmembrane transportGO:00986552660.014
mitotic cell cycleGO:00002781950.014
canonical wnt signaling pathwayGO:00600701300.014
neuronal action potentialGO:0019228540.014
positive regulation of ras gtpase activityGO:0032320650.014
response to radiationGO:00093141650.013
hematopoietic progenitor cell differentiationGO:00022441430.013
response to peptideGO:19016521360.013
chemotaxisGO:00069352470.013
divalent metal ion transportGO:00708381720.013
blood circulationGO:00080151950.013
positive regulation of protein kinase activityGO:00458601440.013
lateral inhibitionGO:004633110.013
regulation of chromatin organizationGO:1902275570.013
sequestering of calcium ionGO:0051208180.013
regulation of ion transportGO:00432692150.013
epithelial cell proliferationGO:00506731740.013
sensory perceptionGO:00076002450.013
response to growth factorGO:00708481980.013
inorganic cation transmembrane transportGO:00986622070.013
epidermis developmentGO:00085441870.013
t cell proliferationGO:00420981200.013
organ growthGO:00352651170.013
maintenance of locationGO:0051235890.013
cell activation involved in immune responseGO:00022631260.013
regulation of cell motilityGO:20001452360.013
synaptic transmissionGO:00072683290.013
ion transmembrane transportGO:00342203610.013
lymphocyte activation involved in immune responseGO:0002285930.013
regulation of proteolysisGO:00301621640.013
reactive oxygen species metabolic processGO:0072593840.013
synapse organizationGO:00508081250.013
lung developmentGO:00303241640.013
response to insulinGO:00328681000.013
anion transportGO:00068201770.013
nuclear divisionGO:00002801580.013
negative regulation of cell activationGO:00508661110.013
microtubule cytoskeleton organizationGO:00002261570.012
cellular response to biotic stimulusGO:0071216920.012
regulation of protein catabolic processGO:00421761080.012
cellular carbohydrate metabolic processGO:00442621190.012
small molecule biosynthetic processGO:00442831320.012
leukocyte activation involved in immune responseGO:00023661260.012
positive regulation of secretion by cellGO:19035321140.012
protein import into nucleusGO:0006606950.012
learning or memoryGO:00076111480.012
response to oxidative stressGO:00069791230.012
protein localization to nucleusGO:00345041210.012
nuclear transportGO:00511691390.012
positive regulation of growthGO:00459271040.012
organophosphate biosynthetic processGO:00904071220.012
phospholipid metabolic processGO:0006644870.012
heart contractionGO:0060047930.012
fatty acid metabolic processGO:00066311210.012
regulation of cell projection organizationGO:00313442060.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
organelle localizationGO:00516401790.012
positive regulation of kinase activityGO:00336741550.012
regulation of cell cycle processGO:00105641600.012
glycoprotein metabolic processGO:00091001160.012
regulation of cytoskeleton organizationGO:00514931220.012
negative regulation of synapse assemblyGO:005196430.012
cellular response to organic cyclic compoundGO:0071407870.012
nucleoside phosphate biosynthetic processGO:1901293790.012
embryonic epithelial tube formationGO:00018381300.012
embryonic organ morphogenesisGO:00485622760.012
regulation of histone modificationGO:0031056560.012
cellular response to molecule of bacterial originGO:0071219830.012
regulation of lymphocyte proliferationGO:00506701170.012
regulation of protein transportGO:00512231630.012
embryonic placenta developmentGO:0001892980.012
positive regulation of programmed cell deathGO:00430682180.011
organic acid biosynthetic processGO:0016053860.011
regulation of cytoplasmic transportGO:19036491120.011
carbohydrate homeostasisGO:00335001280.011
modification dependent macromolecule catabolic processGO:00436321330.011
positive regulation of apoptotic processGO:00430652170.011
positive regulation of cell projection organizationGO:0031346950.011
regulation of cell migrationGO:00303342190.011
dendrite developmentGO:00163581150.011
anatomical structure homeostasisGO:00602491450.011
regulation of cell adhesionGO:00301551540.011
olfactory learningGO:000835520.011
calcium ion transportGO:00068161590.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
cell growthGO:00160491300.011
protein processingGO:00164851630.011
nucleocytoplasmic transportGO:00069131390.011
regulation of transmembrane transportGO:00347621280.011
regulation of cellular response to stressGO:00801351590.011
regulation of histone methylationGO:0031060300.011
myeloid cell homeostasisGO:00022621140.011
protein localization to membraneGO:00726571080.011
central nervous system neuron differentiationGO:00219531620.011
extracellular matrix organizationGO:00301981470.011
regulation of striated muscle cell differentiationGO:0051153810.011
cellular response to lipopolysaccharideGO:0071222770.011
regulation of lymphocyte differentiationGO:00456191070.011
muscle contractionGO:00069361010.011
modification dependent protein catabolic processGO:00199411330.011
regulation of stem cell proliferationGO:0072091780.011
response to nutrient levelsGO:00316671090.011
response to oxygen levelsGO:0070482620.011
activation of immune responseGO:00022531380.011
negative regulation of neuron differentiationGO:00456651010.011
cellular protein catabolic processGO:00442571550.011
purine nucleotide biosynthetic processGO:0006164650.011
spermatid developmentGO:00072861080.011
regulation of protein processingGO:0070613960.010
negative regulation of kinase activityGO:0033673810.010
meiotic nuclear divisionGO:00071261150.010
response to extracellular stimulusGO:00099911270.010
action potentialGO:0001508780.010
neuron deathGO:00709971540.010
regulation of lipid metabolic processGO:00192161180.010
stem cell maintenanceGO:00198271300.010
bmp signaling pathwayGO:0030509930.010
rna processingGO:00063961050.010
regulation of ossificationGO:00302781120.010
digestive system developmentGO:00551232000.010
reactive nitrogen species metabolic processGO:200105700.010
retina development in camera type eyeGO:00600411190.010
regulation of hormone secretionGO:0046883880.010
regulation of peptide secretionGO:0002791770.010
mitotic cytokinesisGO:000028140.010
protein targetingGO:00066051430.010
regulation of ion transmembrane transportGO:00347651190.010
nucleotide biosynthetic processGO:0009165780.010
regulation of metal ion transportGO:00109591060.010
regulation of inflammatory responseGO:00507271470.010
mrna metabolic processGO:0016071840.010
wound healingGO:00420601570.010
neural precursor cell proliferationGO:00613511210.010
carboxylic acid biosynthetic processGO:0046394860.010
regulation of myotube differentiationGO:0010830620.010
positive regulation of protein transportGO:0051222930.010
monosaccharide transportGO:0015749580.010
germ cell developmentGO:00072811850.010

Aff3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.032
disease of anatomical entityDOID:700.032
central nervous system diseaseDOID:33100.013
disease of metabolismDOID:001466700.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.011
organ system cancerDOID:005068600.011