| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.806 | Mouse |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.572 | |
| leukocyte migration | GO:0050900 | 124 | 0.491 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.491 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.481 | |
| positive regulation of ras gtpase activity | GO:0032320 | 65 | 0.477 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.474 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.460 | |
| activation of rac gtpase activity | GO:0032863 | 2 | 0.445 | Fly |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.442 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.422 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.419 | |
| vesicle fusion | GO:0006906 | 16 | 0.416 | |
| organelle fusion | GO:0048284 | 28 | 0.396 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.396 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.393 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.391 | Fly |
| gtp catabolic process | GO:0006184 | 143 | 0.384 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.384 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.384 | |
| cation transport | GO:0006812 | 399 | 0.381 | |
| membrane fusion | GO:0061025 | 38 | 0.380 | |
| cell adhesion | GO:0007155 | 329 | 0.363 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.359 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.357 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.355 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.353 | |
| synaptic transmission | GO:0007268 | 329 | 0.352 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.338 | |
| axon guidance | GO:0007411 | 141 | 0.330 | Fly |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.326 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.323 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.299 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.297 | |
| amine metabolic process | GO:0009308 | 45 | 0.295 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.286 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.285 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.284 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.275 | Mouse |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.274 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.270 | Mouse |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.265 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.264 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.263 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.260 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.258 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.254 | Fly |
| regulation of cell adhesion | GO:0030155 | 154 | 0.251 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.250 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.247 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.237 | |
| positive regulation of cell adhesion | GO:0045785 | 80 | 0.235 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.235 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.228 | |
| actin filament organization | GO:0007015 | 113 | 0.228 | Fly |
| multicellular organism growth | GO:0035264 | 161 | 0.220 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.220 | |
| actin cytoskeleton reorganization | GO:0031532 | 21 | 0.219 | Fly |
| phospholipid metabolic process | GO:0006644 | 87 | 0.219 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.218 | |
| regulation of insulin receptor signaling pathway | GO:0046626 | 21 | 0.215 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.212 | |
| cell growth involved in cardiac muscle cell development | GO:0061049 | 3 | 0.204 | |
| regulation of defense response | GO:0031347 | 233 | 0.201 | |
| cell fate commitment | GO:0045165 | 210 | 0.200 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.198 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.198 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.191 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.190 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.186 | Fly |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.186 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.184 | |
| transmembrane transport | GO:0055085 | 412 | 0.183 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.178 | |
| fat cell differentiation | GO:0045444 | 160 | 0.177 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.174 | |
| oxidation reduction process | GO:0055114 | 342 | 0.174 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.173 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.173 | |
| phenol containing compound metabolic process | GO:0018958 | 60 | 0.172 | Fly |
| immune effector process | GO:0002252 | 321 | 0.172 | Fly |
| superoxide metabolic process | GO:0006801 | 27 | 0.172 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.171 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.171 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.170 | |
| t cell differentiation | GO:0030217 | 174 | 0.168 | Mouse |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.167 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.166 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.164 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.162 | |
| positive regulation of lipid kinase activity | GO:0090218 | 11 | 0.158 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.158 | |
| anion transport | GO:0006820 | 177 | 0.156 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.155 | |
| mapk cascade | GO:0000165 | 281 | 0.153 | |
| fatty acid metabolic process | GO:0006631 | 121 | 0.153 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.151 | |
| myeloid leukocyte migration | GO:0097529 | 57 | 0.150 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.149 | |
| granulocyte chemotaxis | GO:0071621 | 39 | 0.148 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.147 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.146 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.144 | |
| neutrophil migration | GO:1990266 | 37 | 0.144 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.144 | |
| activation of ras gtpase activity | GO:0032856 | 11 | 0.144 | Fly |
| heterocycle catabolic process | GO:0046700 | 280 | 0.141 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.141 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.140 | |
| renal system development | GO:0072001 | 225 | 0.139 | |
| phagocytosis | GO:0006909 | 66 | 0.138 | Mouse |
| regulation of activation of jak2 kinase activity | GO:0010534 | 1 | 0.138 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.138 | |
| wound healing | GO:0042060 | 157 | 0.137 | |
| physiological cardiac muscle hypertrophy | GO:0003301 | 3 | 0.136 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.136 | |
| calcium ion transport | GO:0006816 | 159 | 0.134 | |
| activation of janus kinase activity | GO:0042976 | 2 | 0.134 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.131 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.131 | |
| inflammatory response | GO:0006954 | 244 | 0.130 | |
| lamellipodium organization | GO:0097581 | 29 | 0.130 | |
| regulation of cell motility | GO:2000145 | 236 | 0.130 | |
| t cell activation | GO:0042110 | 289 | 0.130 | Mouse |
| peptide secretion | GO:0002790 | 114 | 0.130 | |
| response to growth factor | GO:0070848 | 198 | 0.127 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.126 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.126 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.125 | Mouse |
| chemotaxis | GO:0006935 | 247 | 0.122 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.122 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.119 | |
| cation homeostasis | GO:0055080 | 212 | 0.119 | |
| response to nutrient levels | GO:0031667 | 109 | 0.119 | |
| secondary metabolic process | GO:0019748 | 18 | 0.116 | Fly |
| muscle adaptation | GO:0043500 | 39 | 0.115 | |
| muscle contraction | GO:0006936 | 101 | 0.115 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.115 | |
| regulation of ion transport | GO:0043269 | 215 | 0.114 | |
| cytokine production | GO:0001816 | 319 | 0.112 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.111 | |
| intracellular protein transport | GO:0006886 | 204 | 0.109 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.109 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.108 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.108 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.107 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.107 | |
| neurotransmitter transport | GO:0006836 | 76 | 0.105 | |
| cellular homeostasis | GO:0019725 | 240 | 0.105 | |
| vesicle organization | GO:0016050 | 60 | 0.103 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.103 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.103 | |
| response to corticosterone | GO:0051412 | 1 | 0.102 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.101 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.100 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.098 | |
| organ regeneration | GO:0031100 | 2 | 0.098 | |
| neuron death | GO:0070997 | 154 | 0.096 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.096 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.095 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.095 | |
| myotube differentiation | GO:0014902 | 105 | 0.094 | Fly |
| positive regulation of lipid metabolic process | GO:0045834 | 40 | 0.093 | |
| organic anion transport | GO:0015711 | 137 | 0.093 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.093 | |
| gtp metabolic process | GO:0046039 | 144 | 0.092 | |
| tissue remodeling | GO:0048771 | 102 | 0.090 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.088 | |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.088 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.087 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.086 | |
| response to insulin | GO:0032868 | 100 | 0.086 | |
| regulation of neuron death | GO:1901214 | 134 | 0.086 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.085 | |
| regulation of cell migration | GO:0030334 | 219 | 0.085 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.084 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.082 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.082 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.082 | |
| regulation of system process | GO:0044057 | 200 | 0.081 | |
| catecholamine metabolic process | GO:0006584 | 30 | 0.081 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.081 | |
| regulation of lipid metabolic process | GO:0019216 | 118 | 0.081 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.080 | |
| neurotrophin trk receptor signaling pathway | GO:0048011 | 8 | 0.080 | |
| vesicle localization | GO:0051648 | 86 | 0.079 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.078 | |
| respiratory tube development | GO:0030323 | 167 | 0.078 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.078 | |
| gland development | GO:0048732 | 330 | 0.076 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.076 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.076 | |
| skeletal system development | GO:0001501 | 356 | 0.075 | |
| ossification | GO:0001503 | 216 | 0.075 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.075 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.075 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.074 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.073 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.073 | |
| gliogenesis | GO:0042063 | 141 | 0.073 | |
| positive regulation of rho gtpase activity | GO:0032321 | 41 | 0.073 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.073 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.072 | |
| negative regulation of growth | GO:0045926 | 99 | 0.071 | |
| cell chemotaxis | GO:0060326 | 81 | 0.070 | |
| circulatory system process | GO:0003013 | 197 | 0.070 | |
| hormone metabolic process | GO:0042445 | 86 | 0.070 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.069 | |
| embryonic placenta development | GO:0001892 | 98 | 0.069 | |
| placenta development | GO:0001890 | 140 | 0.069 | |
| hemostasis | GO:0007599 | 78 | 0.068 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.068 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.068 | |
| ribose phosphate biosynthetic process | GO:0046390 | 59 | 0.068 | |
| coagulation | GO:0050817 | 78 | 0.067 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.067 | |
| cellular response to inorganic substance | GO:0071241 | 37 | 0.067 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.066 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.066 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.065 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.065 | |
| physiological muscle hypertrophy | GO:0003298 | 3 | 0.065 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.065 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.065 | |
| camera type eye development | GO:0043010 | 266 | 0.065 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.064 | |
| skin development | GO:0043588 | 220 | 0.064 | |
| heart morphogenesis | GO:0003007 | 178 | 0.064 | |
| regulation of fat cell differentiation | GO:0045598 | 81 | 0.064 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.063 | |
| negative regulation of synaptic vesicle transport | GO:1902804 | 3 | 0.062 | |
| alpha beta t cell differentiation | GO:0046632 | 69 | 0.062 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.062 | |
| urogenital system development | GO:0001655 | 261 | 0.062 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.061 | |
| circadian rhythm | GO:0007623 | 114 | 0.061 | |
| pigmentation | GO:0043473 | 71 | 0.061 | |
| exocytosis | GO:0006887 | 121 | 0.061 | |
| heart process | GO:0003015 | 94 | 0.060 | |
| regulation of circadian sleep wake cycle sleep | GO:0045187 | 3 | 0.060 | |
| connective tissue development | GO:0061448 | 179 | 0.060 | |
| adipose tissue development | GO:0060612 | 25 | 0.060 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.060 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.059 | |
| cell substrate adhesion | GO:0031589 | 130 | 0.059 | |
| regulation of neurotransmitter levels | GO:0001505 | 87 | 0.059 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.058 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.058 | |
| alpha beta t cell activation | GO:0046631 | 91 | 0.058 | |
| heart contraction | GO:0060047 | 93 | 0.058 | |
| negative regulation of synaptic vesicle exocytosis | GO:2000301 | 3 | 0.058 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.058 | |
| bone development | GO:0060348 | 120 | 0.057 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.057 | |
| negative regulation of cellular response to insulin stimulus | GO:1900077 | 16 | 0.057 | |
| erbb signaling pathway | GO:0038127 | 32 | 0.057 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.057 | |
| norepinephrine transport | GO:0015874 | 2 | 0.057 | |
| cellular response to metal ion | GO:0071248 | 31 | 0.057 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.056 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.056 | Human |
| negative regulation of peptidyl tyrosine phosphorylation | GO:0050732 | 17 | 0.056 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.055 | |
| sensory perception | GO:0007600 | 245 | 0.055 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.055 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.055 | |
| kidney development | GO:0001822 | 213 | 0.055 | |
| kidney epithelium development | GO:0072073 | 121 | 0.055 | |
| epidermal growth factor receptor signaling pathway | GO:0007173 | 28 | 0.054 | |
| axonogenesis | GO:0007409 | 274 | 0.054 | Fly |
| negative regulation of defense response | GO:0031348 | 77 | 0.054 | |
| dephosphorylation | GO:0016311 | 129 | 0.054 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.054 | |
| chondrocyte differentiation | GO:0002062 | 72 | 0.054 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.054 | |
| pigment metabolic process | GO:0042440 | 32 | 0.053 | Fly |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.053 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.053 | |
| endocytosis | GO:0006897 | 168 | 0.053 | Mouse |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.053 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.052 | |
| alcohol metabolic process | GO:0006066 | 116 | 0.052 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.052 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.052 | |
| negative regulation of phagocytosis | GO:0050765 | 4 | 0.052 | |
| neutrophil chemotaxis | GO:0030593 | 36 | 0.052 | |
| cognition | GO:0050890 | 149 | 0.052 | |
| glucocorticoid biosynthetic process | GO:0006704 | 5 | 0.051 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.051 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.051 | |
| negative regulation of neurotransmitter transport | GO:0051589 | 7 | 0.050 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.050 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.050 | |
| regulation of blood coagulation | GO:0030193 | 28 | 0.050 | |
| response to inactivity | GO:0014854 | 4 | 0.050 | |
| regulation of muscle hypertrophy | GO:0014743 | 13 | 0.050 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.049 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.049 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.049 | |
| peptide metabolic process | GO:0006518 | 46 | 0.049 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 42 | 0.048 | Fly |
| multi multicellular organism process | GO:0044706 | 109 | 0.048 | |
| regulation of synaptic plasticity | GO:0048167 | 87 | 0.048 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.048 | |
| organic acid transport | GO:0015849 | 101 | 0.048 | |
| positive regulation of growth | GO:0045927 | 104 | 0.048 | |
| fibroblast migration | GO:0010761 | 21 | 0.048 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.047 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.047 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.047 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.047 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.047 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.047 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.047 | |
| monoamine transport | GO:0015844 | 33 | 0.047 | |
| phenol containing compound biosynthetic process | GO:0046189 | 21 | 0.047 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.047 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.047 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.046 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.046 | |
| modification by symbiont of host morphology or physiology | GO:0044003 | 4 | 0.046 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.045 | Human |
| positive regulation of cell activation | GO:0050867 | 158 | 0.045 | Human |
| sensory perception of light stimulus | GO:0050953 | 54 | 0.045 | |
| glucose homeostasis | GO:0042593 | 128 | 0.045 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.045 | |
| lung development | GO:0030324 | 164 | 0.045 | |
| protein localization to membrane | GO:0072657 | 108 | 0.044 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 65 | 0.044 | |
| rhythmic process | GO:0048511 | 174 | 0.044 | |
| regulation of protein localization | GO:0032880 | 231 | 0.044 | |
| amino acid transport | GO:0006865 | 61 | 0.044 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.044 | |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.044 | |
| membrane organization | GO:0061024 | 245 | 0.044 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.044 | |
| developmental maturation | GO:0021700 | 193 | 0.044 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.043 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.043 | |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.042 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.042 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.042 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.042 | |
| adenylate cyclase modulating g protein coupled receptor signaling pathway | GO:0007188 | 54 | 0.042 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.042 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.041 | |
| response to amino acid | GO:0043200 | 37 | 0.041 | |
| regulation of peptidyl serine phosphorylation | GO:0033135 | 39 | 0.041 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.041 | |
| positive regulation of nucleotide biosynthetic process | GO:0030810 | 26 | 0.041 | |
| neuron projection guidance | GO:0097485 | 141 | 0.041 | Fly |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.041 | |
| respiratory system development | GO:0060541 | 190 | 0.041 | Fly |
| negative regulation of neuron death | GO:1901215 | 98 | 0.041 | |
| positive regulation of apoptotic process involved in mammary gland involution | GO:0060058 | 4 | 0.041 | |
| amide transport | GO:0042886 | 138 | 0.041 | |
| smooth muscle contraction | GO:0006939 | 44 | 0.041 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.040 | |
| regulation of secretion | GO:0051046 | 274 | 0.040 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.040 | |
| response to peptide | GO:1901652 | 136 | 0.040 | |
| protein localization to organelle | GO:0033365 | 185 | 0.040 | |
| response to osmotic stress | GO:0006970 | 21 | 0.040 | |
| chromatin mediated maintenance of transcription | GO:0048096 | 2 | 0.040 | |
| mesonephros development | GO:0001823 | 97 | 0.040 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.040 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.040 | |
| response to oxidative stress | GO:0006979 | 123 | 0.040 | |
| neurotransmitter secretion | GO:0007269 | 62 | 0.040 | |
| peptide transport | GO:0015833 | 133 | 0.039 | |
| hexose metabolic process | GO:0019318 | 98 | 0.039 | |
| regulation of calcium ion transport | GO:0051924 | 69 | 0.039 | |
| response to vitamin d | GO:0033280 | 3 | 0.039 | |
| response to radiation | GO:0009314 | 165 | 0.039 | |
| dendrite development | GO:0016358 | 115 | 0.038 | |
| response to peptide hormone | GO:0043434 | 127 | 0.038 | |
| organelle assembly | GO:0070925 | 177 | 0.038 | |
| cellular response to peptide | GO:1901653 | 92 | 0.038 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.038 | |
| regulation of ion homeostasis | GO:2000021 | 64 | 0.038 | |
| blood circulation | GO:0008015 | 195 | 0.038 | |
| negative regulation of fibroblast migration | GO:0010764 | 2 | 0.038 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.037 | |
| body fluid secretion | GO:0007589 | 53 | 0.037 | |
| action potential | GO:0001508 | 78 | 0.037 | |
| female gamete generation | GO:0007292 | 74 | 0.037 | |
| cellular amide metabolic process | GO:0043603 | 58 | 0.037 | |
| regulation of hormone secretion | GO:0046883 | 88 | 0.037 | |
| regulation of systemic arterial blood pressure | GO:0003073 | 61 | 0.037 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.037 | |
| regulation of norepinephrine secretion | GO:0014061 | 2 | 0.037 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.036 | |
| regulation of notch signaling pathway | GO:0008593 | 35 | 0.036 | Worm |
| muscle system process | GO:0003012 | 141 | 0.036 | |
| response to inorganic substance | GO:0010035 | 96 | 0.036 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.036 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.036 | |
| negative regulation of insulin receptor signaling pathway | GO:0046627 | 14 | 0.035 | |
| leukocyte chemotaxis | GO:0030595 | 69 | 0.035 | |
| regulation of smad protein import into nucleus | GO:0060390 | 3 | 0.035 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.035 | |
| learning or memory | GO:0007611 | 148 | 0.034 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.034 | |
| photoreceptor cell development | GO:0042461 | 40 | 0.034 | |
| regulation of wound healing | GO:0061041 | 40 | 0.034 | |
| phosphatidylinositol metabolic process | GO:0046488 | 45 | 0.034 | |
| response to alcohol | GO:0097305 | 48 | 0.034 | |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.034 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 77 | 0.034 | |
| organ growth | GO:0035265 | 117 | 0.034 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.034 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.034 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.034 | |
| maintenance of location | GO:0051235 | 89 | 0.034 | |
| smad protein complex assembly | GO:0007183 | 1 | 0.034 | |
| regulation of muscle adaptation | GO:0043502 | 31 | 0.033 | |
| schwann cell development | GO:0014044 | 22 | 0.033 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.033 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.033 | |
| regulation of exocytosis | GO:0017157 | 61 | 0.033 | |
| myeloid leukocyte mediated immunity | GO:0002444 | 42 | 0.033 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.033 | |
| ureteric bud development | GO:0001657 | 94 | 0.033 | |
| blood coagulation | GO:0007596 | 76 | 0.033 | |
| regulation of cell activation | GO:0050865 | 289 | 0.032 | Human |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.032 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.032 | |
| regulation of lipid kinase activity | GO:0043550 | 14 | 0.032 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.032 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.032 | |
| regulation of hemostasis | GO:1900046 | 28 | 0.032 | |
| regulation of angiogenesis | GO:0045765 | 81 | 0.032 | |
| rap protein signal transduction | GO:0032486 | 3 | 0.032 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.031 | |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.031 | |
| sperm individualization | GO:0007291 | 1 | 0.031 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.031 | |
| regulation of coagulation | GO:0050818 | 31 | 0.031 | |
| glial cell differentiation | GO:0010001 | 131 | 0.031 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.031 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.031 | |
| regulation of circadian rhythm | GO:0042752 | 58 | 0.031 | |
| cell maturation | GO:0048469 | 127 | 0.030 | |
| regulation of muscle contraction | GO:0006937 | 49 | 0.030 | |
| learning | GO:0007612 | 98 | 0.030 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.030 | |
| epidermis development | GO:0008544 | 187 | 0.030 | |
| microglia differentiation | GO:0014004 | 2 | 0.030 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.030 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.030 | |
| hormone secretion | GO:0046879 | 128 | 0.030 | |
| response to monosaccharide | GO:0034284 | 67 | 0.029 | |
| negative regulation of cytokine production | GO:0001818 | 84 | 0.029 | |
| regulation of circadian sleep wake cycle | GO:0042749 | 3 | 0.029 | |
| regulation of gluconeogenesis | GO:0006111 | 30 | 0.029 | |
| negative regulation of ras protein signal transduction | GO:0046580 | 18 | 0.029 | |
| nephron tubule development | GO:0072080 | 84 | 0.029 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 93 | 0.029 | |
| regulation of cell shape | GO:0008360 | 39 | 0.029 | Fly |
| rac protein signal transduction | GO:0016601 | 13 | 0.029 | |
| stem cell development | GO:0048864 | 219 | 0.029 | |
| steroid metabolic process | GO:0008202 | 119 | 0.029 | |
| renal tubule development | GO:0061326 | 87 | 0.029 | |
| forebrain development | GO:0030900 | 302 | 0.029 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.029 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.029 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.029 | |
| cellular response to carbohydrate stimulus | GO:0071322 | 50 | 0.028 | |
| chromatin modification | GO:0016568 | 187 | 0.028 | |
| superoxide anion generation | GO:0042554 | 11 | 0.028 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.028 | |
| syncytium formation | GO:0006949 | 43 | 0.028 | Fly |
| response to light stimulus | GO:0009416 | 135 | 0.028 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.028 | |
| purine containing compound biosynthetic process | GO:0072522 | 70 | 0.028 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 59 | 0.028 | |
| negative regulation of cell migration | GO:0030336 | 59 | 0.028 | |
| t cell proliferation | GO:0042098 | 120 | 0.028 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.028 | |
| mesonephric tubule development | GO:0072164 | 94 | 0.028 | |
| primary neural tube formation | GO:0014020 | 95 | 0.028 | |
| dopamine metabolic process | GO:0042417 | 23 | 0.028 | |
| regulation of neurotransmitter transport | GO:0051588 | 35 | 0.028 | |
| insulin receptor signaling pathway | GO:0008286 | 49 | 0.028 | |
| insulin secretion | GO:0030073 | 89 | 0.028 | |
| adaptive immune response | GO:0002250 | 155 | 0.028 | |
| granulocyte migration | GO:0097530 | 43 | 0.028 | |
| neutrophil mediated immunity | GO:0002446 | 19 | 0.027 | |
| locomotory behavior | GO:0007626 | 195 | 0.027 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.027 | |
