Mus musculus

0 known processes

Smpd1

sphingomyelin phosphodiesterase 1, acid lysosomal

(Aliases: aSMase,Zn-SMase,A-SMase,ASM)

Smpd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of secretionGO:00510462740.081
nucleoside phosphate metabolic processGO:00067533380.079
regulation of cellular amine metabolic processGO:0033238200.069
cellular lipid metabolic processGO:00442553230.067
Human
regulation of cellular amino acid metabolic processGO:000652150.066
cellular amino acid metabolic processGO:00065201030.066
glycoprotein biosynthetic processGO:0009101890.058
amine metabolic processGO:0009308450.047
carbohydrate metabolic processGO:00059752300.043
cellular response to extracellular stimulusGO:0031668810.043
regulation of cellular ketone metabolic processGO:0010565660.041
vacuole organizationGO:0007033380.040
organophosphate catabolic processGO:00464342320.040
nucleobase containing small molecule metabolic processGO:00550863520.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
cellular amine metabolic processGO:0044106440.037
transmembrane transportGO:00550854120.036
sensory system developmentGO:004888030.036
sulfur compound metabolic processGO:00067901000.036
carbohydrate derivative biosynthetic processGO:19011371830.036
cation transmembrane transportGO:00986552660.034
intracellular protein transportGO:00068862040.033
negative regulation of molecular functionGO:00440922580.033
Human
positive regulation of protein modification processGO:00314012990.033
Human
glycoprotein metabolic processGO:00091001160.032
peptidyl amino acid modificationGO:00181933360.032
skin developmentGO:00435882200.031
endomembrane system organizationGO:00102561470.031
lipid transportGO:0006869980.030
renal system developmentGO:00720012250.030
cation transportGO:00068123990.029
positive regulation of cellular amine metabolic processGO:003324050.029
anatomical structure homeostasisGO:00602491450.029
lipid localizationGO:00108761260.028
cellular response to growth factor stimulusGO:00713631970.028
negative regulation of intracellular signal transductionGO:19025321670.027
Human
rho protein signal transductionGO:0007266320.027
action potentialGO:0001508780.027
nucleotide metabolic processGO:00091173320.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.026
heterocycle catabolic processGO:00467002800.026
leukocyte differentiationGO:00025213420.025
cellular ketone metabolic processGO:0042180840.025
mapk cascadeGO:00001652810.025
Human
positive regulation of apoptotic processGO:00430652170.025
axonogenesisGO:00074092740.025
ossificationGO:00015032160.024
negative regulation of cellular amine metabolic processGO:003323910.024
inorganic cation transmembrane transportGO:00986622070.024
inorganic ion transmembrane transportGO:00986602340.024
heart morphogenesisGO:00030071780.023
purine containing compound catabolic processGO:00725232130.023
protein glycosylationGO:0006486550.023
organelle assemblyGO:00709251770.023
cellular homeostasisGO:00197252400.023
nucleoside phosphate catabolic processGO:19012922220.022
carbohydrate derivative catabolic processGO:19011362310.022
endocytosisGO:00068971680.022
macroautophagyGO:0016236210.021
lipid biosynthetic processGO:00086101790.021
Human
urogenital system developmentGO:00016552610.021
apoptotic signaling pathwayGO:00971903060.021
circulatory system processGO:00030131970.021
myelinationGO:0042552740.020
reactive oxygen species metabolic processGO:0072593840.020
positive regulation of leukocyte differentiationGO:1902107860.020
plasma membrane organizationGO:0007009900.020
dna metabolic processGO:00062593030.019
negative regulation of protein metabolic processGO:00512482820.019
Human
oxidation reduction processGO:00551143420.019
cellular divalent inorganic cation homeostasisGO:00725031270.019
response to extracellular stimulusGO:00099911270.019
positive regulation of programmed cell deathGO:00430682180.019
developmental maturationGO:00217001930.019
regulation of leukocyte differentiationGO:19021051590.019
monocarboxylic acid metabolic processGO:00327871910.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
inflammatory responseGO:00069542440.019
glycosyl compound catabolic processGO:19016582060.019
ion transmembrane transportGO:00342203610.019
cellular response to nutrient levelsGO:0031669640.019
negative regulation of cell proliferationGO:00082852960.019
cellular response to external stimulusGO:0071496880.019
regulation of cell activationGO:00508652890.018
maintenance of locationGO:0051235890.018
response to organonitrogen compoundGO:00102432460.018
purine ribonucleotide catabolic processGO:00091542080.018
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.018
cell maturationGO:00484691270.018
cellular nitrogen compound catabolic processGO:00442702800.018
chemotaxisGO:00069352470.018
cation homeostasisGO:00550802120.018
multicellular organismal homeostasisGO:00488711640.017
macromolecule glycosylationGO:0043413550.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
nucleotide sugar metabolic processGO:000922540.017
nitrogen compound transportGO:00717052710.017
negative regulation of growthGO:0045926990.016
small gtpase mediated signal transductionGO:0007264970.016
ribonucleotide metabolic processGO:00092592910.016
response to inorganic substanceGO:0010035960.016
cellular chemical homeostasisGO:00550822150.016
dephosphorylationGO:00163111290.016
Human
ras protein signal transductionGO:0007265770.016
protein maturationGO:00516041760.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.016
positive regulation of cell deathGO:00109422240.016
regulation of cellular catabolic processGO:00313292420.016
glycerolipid metabolic processGO:00464861220.016
positive regulation of secretion by cellGO:19035321140.016
negative regulation of nervous system developmentGO:00519611560.016
macromolecule catabolic processGO:00090572810.016
blood circulationGO:00080151950.016
regulation of secretion by cellGO:19035302490.015
cellular lipid catabolic processGO:0044242520.015
glycosylationGO:0070085620.015
extracellular structure organizationGO:00430621480.015
regulation of membrane potentialGO:00423911920.015
negative regulation of phosphorylationGO:00423261660.015
Human
sensory organ morphogenesisGO:00905962420.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
organonitrogen compound catabolic processGO:19015652640.015
nucleotide catabolic processGO:00091662170.015
organonitrogen compound biosynthetic processGO:19015661920.015
Human
response to nutrient levelsGO:00316671090.015
autophagyGO:0006914450.015
nucleoside triphosphate catabolic processGO:00091432050.015
regulation of cellular response to stressGO:00801351590.015
ear developmentGO:00435832000.015
pigmentationGO:0043473710.015
camera type eye developmentGO:00430102660.015
negative regulation of phosphate metabolic processGO:00459361840.015
Human
t cell activationGO:00421102890.015
immune effector processGO:00022523210.015
lateral line system developmentGO:004892510.015
protein processingGO:00164851630.015
respiratory system developmentGO:00605411900.014
cellular carbohydrate metabolic processGO:00442621190.014
hair cell differentiationGO:0035315400.014
aromatic compound catabolic processGO:00194392860.014
attachment of spindle microtubules to kinetochoreGO:000860840.014
protein kinase b signalingGO:0043491740.014
interspecies interaction between organismsGO:0044419830.014
fatty acid metabolic processGO:00066311210.014
glycosyl compound metabolic processGO:19016572460.014
regulation of protein localizationGO:00328802310.014
regulation of cytokine productionGO:00018172660.014
regulation of cell cycleGO:00517262810.014
regulation of apoptotic signaling pathwayGO:20012331970.014
lymphocyte differentiationGO:00300982420.014
response to starvationGO:0042594650.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
nucleoside catabolic processGO:00091642060.014
epithelial cell proliferationGO:00506731740.014
protein localization to plasma membraneGO:0072659570.014
negative regulation of phosphorus metabolic processGO:00105631840.013
Human
organic cyclic compound catabolic processGO:19013612950.013
nucleoside metabolic processGO:00091162460.013
generation of precursor metabolites and energyGO:00060911030.013
transmission of nerve impulseGO:0019226760.013
negative regulation of cellular catabolic processGO:0031330470.013
response to oxidative stressGO:00069791230.013
regulation of t cell activationGO:00508631700.013
positive regulation of secretionGO:00510471300.013
negative regulation of synapse assemblyGO:005196430.013
embryonic organ morphogenesisGO:00485622760.013
single organism cell adhesionGO:00986021560.013
peptidyl tyrosine modificationGO:00182121450.013
autophagic vacuole assemblyGO:0000045130.013
regulation of hormone levelsGO:00108172110.013
epidermis developmentGO:00085441870.013
regulation of lymphocyte activationGO:00512492400.013
leukocyte activation involved in immune responseGO:00023661260.013
alcohol metabolic processGO:00060661160.013
positive regulation of lymphocyte activationGO:00512511400.013
organic hydroxy compound metabolic processGO:19016152030.013
regulation of establishment of protein localizationGO:00702011810.013
response to monosaccharideGO:0034284670.013
organelle fissionGO:00482851700.013
germ cell developmentGO:00072811850.013
negative regulation of cell developmentGO:00107211690.013
organelle localizationGO:00516401790.013
cellular response to biotic stimulusGO:0071216920.013
regulation of cell motilityGO:20001452360.013
learning or memoryGO:00076111480.012
regulation of cellular component biogenesisGO:00440871810.012
purine nucleotide metabolic processGO:00061633020.012
muscle system processGO:00030121410.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
glucose homeostasisGO:00425931280.012
ribose phosphate metabolic processGO:00196932910.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
substantia nigra developmentGO:002176220.012
lipid catabolic processGO:0016042690.012
neuronal action potentialGO:0019228540.012
mesoderm developmentGO:00074981000.012
multicellular organism growthGO:00352641610.012
skeletal system developmentGO:00015013560.012
compound eye developmentGO:004874910.012
posttranscriptional regulation of gene expressionGO:00106081550.012
regulation of body fluid levelsGO:00508781620.012
lipoprotein metabolic processGO:0042157430.012
acetate ester transportGO:190137420.012
modification by symbiont of host morphology or physiologyGO:004400340.012
negative regulation of cellular component organizationGO:00511291940.012
lysosome organizationGO:0007040210.012
purine ribonucleotide metabolic processGO:00091502900.012
multicellular organismal signalingGO:0035637910.012
cellular response to oxidative stressGO:0034599760.012
acetylcholine transportGO:001587020.012
male gamete generationGO:00482322850.012
glycerophospholipid metabolic processGO:0006650710.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
wnt signaling pathwayGO:00160551880.012
positive regulation of protein phosphorylationGO:00019342420.012
establishment of protein localization to membraneGO:0090150540.012
mitochondrion organizationGO:00070051340.012
regulation of organelle organizationGO:00330432890.012
glycerolipid biosynthetic processGO:0045017500.012
muscle contractionGO:00069361010.012
organic acid biosynthetic processGO:0016053860.011
regulation of lipid metabolic processGO:00192161180.011
regulation of defense responseGO:00313472330.011
membrane organizationGO:00610242450.011
extracellular matrix organizationGO:00301981470.011
regulation of cell growthGO:0001558910.011
sensory perceptionGO:00076002450.011
myeloid leukocyte differentiationGO:00025731190.011
wound healingGO:00420601570.011
regulation of system processGO:00440572000.011
positive regulation of cell activationGO:00508671580.011
purine nucleoside catabolic processGO:00061522050.011
muscle tissue developmentGO:00605373080.011
neutral lipid metabolic processGO:0006638570.011
purine nucleoside metabolic processGO:00422782410.011
cellular response to starvationGO:0009267570.011
response to epidermal growth factorGO:007084940.011
cellular response to organonitrogen compoundGO:00714171450.011
nucleoside monophosphate metabolic processGO:0009123850.011
regulation of intracellular protein transportGO:0033157820.011
cellular response to cytokine stimulusGO:00713451890.011
respiratory gaseous exchangeGO:0007585430.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
response to peptideGO:19016521360.011
positive regulation of nervous system developmentGO:00519622210.011
modification dependent macromolecule catabolic processGO:00436321330.011
exocytosisGO:00068871210.010
positive regulation of neuron differentiationGO:00456661410.010
regulation of vesicle mediated transportGO:00606271390.010
regulation of lymphocyte differentiationGO:00456191070.010
carboxylic acid biosynthetic processGO:0046394860.010
positive regulation of organelle organizationGO:00106381280.010
fibroblast growth factor receptor signaling pathwayGO:0008543460.010
regulation of multi organism processGO:00439001110.010
organic hydroxy compound transportGO:0015850930.010
negative regulation of protein modification processGO:00314001630.010
Human
ribonucleoside triphosphate metabolic processGO:00091992200.010
cytokine productionGO:00018163190.010
purine containing compound metabolic processGO:00725213110.010
protein modification by small protein conjugationGO:00324461870.010
locomotory behaviorGO:00076261950.010
regulation of transmembrane transportGO:00347621280.010
nucleoside monophosphate catabolic processGO:0009125590.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
cellular amide metabolic processGO:0043603580.010
cellular polysaccharide metabolic processGO:0044264380.010

Smpd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.157
Human
inherited metabolic disorderDOID:65500.039
Human
disease of anatomical entityDOID:700.038
Human
central nervous system diseaseDOID:33100.038
nervous system diseaseDOID:86300.038
brain diseaseDOID:93600.016
sensory system diseaseDOID:005015500.012
acquired metabolic diseaseDOID:006015800.010
cardiovascular system diseaseDOID:128700.010
immune system diseaseDOID:291400.010
Human