Mus musculus

22 known processes

Slc39a8

solute carrier family 39 (metal ion transporter), member 8

(Aliases: BIGM103,Zip8,AA986696,4933419D20Rik)

Slc39a8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.103
transmembrane transportGO:00550854120.094
anion transportGO:00068201770.064
cellular lipid metabolic processGO:00442553230.063
cellular amine metabolic processGO:0044106440.059
organic anion transportGO:00157111370.051
cellular ketone metabolic processGO:0042180840.045
monocarboxylic acid metabolic processGO:00327871910.044
small molecule biosynthetic processGO:00442831320.044
amine metabolic processGO:0009308450.044
apoptotic signaling pathwayGO:00971903060.043
lipid biosynthetic processGO:00086101790.043
ion transmembrane transportGO:00342203610.043
lipid transportGO:0006869980.042
negative regulation of protein metabolic processGO:00512482820.042
carboxylic acid biosynthetic processGO:0046394860.041
regulation of cellular ketone metabolic processGO:0010565660.041
positive regulation of cellular amino acid metabolic processGO:004576430.041
cell adhesionGO:00071553290.040
sulfur compound metabolic processGO:00067901000.039
regulation of cellular amino acid metabolic processGO:000652150.037
nucleobase containing small molecule metabolic processGO:00550863520.037
cellular nitrogen compound catabolic processGO:00442702800.036
nucleoside phosphate metabolic processGO:00067533380.036
cation transportGO:00068123990.035
oxidation reduction processGO:00551143420.035
negative regulation of cellular protein metabolic processGO:00322692470.034
purine containing compound metabolic processGO:00725213110.034
nucleotide metabolic processGO:00091173320.034
regulation of cellular amine metabolic processGO:0033238200.033
immune effector processGO:00022523210.033
regulation of transferase activityGO:00513382630.033
membrane organizationGO:00610242450.033
nitrogen compound transportGO:00717052710.033
purine ribonucleoside metabolic processGO:00461282410.033
ribonucleotide metabolic processGO:00092592910.032
cell cell junction organizationGO:0045216720.032
small gtpase mediated signal transductionGO:0007264970.031
nucleoside metabolic processGO:00091162460.030
glycosyl compound metabolic processGO:19016572460.030
heterocycle catabolic processGO:00467002800.030
anion transmembrane transportGO:0098656710.030
regulation of cell activationGO:00508652890.029
negative regulation of phosphate metabolic processGO:00459361840.029
glycerolipid metabolic processGO:00464861220.029
regulation of hydrolase activityGO:00513362460.029
organic acid transportGO:00158491010.029
negative regulation of phosphorylationGO:00423261660.029
response to acid chemicalGO:00011011110.029
ribose phosphate metabolic processGO:00196932910.028
ribonucleoside metabolic processGO:00091192450.028
inorganic ion transmembrane transportGO:00986602340.028
organic hydroxy compound transportGO:0015850930.028
endocytosisGO:00068971680.028
ras protein signal transductionGO:0007265770.027
nucleoside triphosphate metabolic processGO:00091412300.027
organic hydroxy compound metabolic processGO:19016152030.027
aromatic compound catabolic processGO:00194392860.027
glycosyl compound catabolic processGO:19016582060.027
positive regulation of cellular catabolic processGO:00313311480.027
purine ribonucleotide metabolic processGO:00091502900.027
cation transmembrane transportGO:00986552660.026
negative regulation of phosphorus metabolic processGO:00105631840.026
regulation of mapk cascadeGO:00434082480.026
mapk cascadeGO:00001652810.026
organic acid biosynthetic processGO:0016053860.026
carboxylic acid transportGO:00469421000.026
regulation of protein kinase activityGO:00458592320.026
ribonucleoside catabolic processGO:00424542060.026
cellular homeostasisGO:00197252400.025
organic cyclic compound catabolic processGO:19013612950.025
lipid localizationGO:00108761260.025
regulation of inflammatory responseGO:00507271470.025
positive regulation of protein modification processGO:00314012990.025
negative regulation of molecular functionGO:00440922580.025
cellular response to lipidGO:00713961450.025
response to growth factorGO:00708481980.024
protein ubiquitinationGO:00165671710.024
carbohydrate derivative biosynthetic processGO:19011371830.024
innate immune responseGO:00450871570.024
regulation of homeostatic processGO:00328441820.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
negative regulation of intracellular signal transductionGO:19025321670.024
purine nucleoside metabolic processGO:00422782410.024
rho protein signal transductionGO:0007266320.024
regulation of lymphocyte activationGO:00512492400.024
cellular chemical homeostasisGO:00550822150.024
macromolecule catabolic processGO:00090572810.024
leukocyte differentiationGO:00025213420.023
regulation of kinase activityGO:00435492490.023
organonitrogen compound catabolic processGO:19015652640.023
organonitrogen compound biosynthetic processGO:19015661920.023
carbohydrate derivative catabolic processGO:19011362310.023
regulation of response to woundingGO:19030341890.023
wnt signaling pathwayGO:00160551880.023
inorganic cation transmembrane transportGO:00986622070.023
positive regulation of protein phosphorylationGO:00019342420.022
protein modification by small protein conjugationGO:00324461870.022
cofactor metabolic processGO:0051186800.022
regulation of cell projection organizationGO:00313442060.022
positive regulation of cellular amine metabolic processGO:003324050.022
positive regulation of hydrolase activityGO:00513451480.022
fatty acid metabolic processGO:00066311210.022
nucleoside phosphate catabolic processGO:19012922220.022
regulation of apoptotic signaling pathwayGO:20012331970.022
regulation of cellular catabolic processGO:00313292420.022
regulation of membrane potentialGO:00423911920.022
proteolysis involved in cellular protein catabolic processGO:00516031470.022
regulation of organelle organizationGO:00330432890.022
purine nucleotide metabolic processGO:00061633020.022
negative regulation of cellular amino acid metabolic processGO:004576300.022
protein modification by small protein conjugation or removalGO:00706472070.022
purine ribonucleoside catabolic processGO:00461302050.021
negative regulation of immune system processGO:00026832090.021
response to extracellular stimulusGO:00099911270.021
Mouse
cell type specific apoptotic processGO:00972852680.021
intracellular protein transportGO:00068862040.021
negative regulation of protein phosphorylationGO:00019331260.021
purine nucleoside catabolic processGO:00061522050.021
negative regulation of cellular amine metabolic processGO:003323910.021
response to molecule of bacterial originGO:00022371430.021
transmission of nerve impulseGO:0019226760.021
renal system developmentGO:00720012250.021
sensory organ morphogenesisGO:00905962420.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
regulation of cell migrationGO:00303342190.020
purine containing compound catabolic processGO:00725232130.020
nucleotide catabolic processGO:00091662170.020
cytoplasmic transportGO:00164822340.020
blood circulationGO:00080151950.020
cellular modified amino acid metabolic processGO:0006575630.020
modification dependent macromolecule catabolic processGO:00436321330.020
inflammatory responseGO:00069542440.020
regulation of defense responseGO:00313472330.020
purine nucleotide catabolic processGO:00061952110.020
chemotaxisGO:00069352470.020
regulation of hormone levelsGO:00108172110.019
protein maturationGO:00516041760.019
skeletal system developmentGO:00015013560.019
response to lipopolysaccharideGO:00324961280.019
sensory perceptionGO:00076002450.019
regulation of t cell activationGO:00508631700.019
single organism cell adhesionGO:00986021560.019
ubiquitin dependent protein catabolic processGO:00065111290.019
multicellular organismal homeostasisGO:00488711640.019
cation homeostasisGO:00550802120.019
positive regulation of cell deathGO:00109422240.019
peptidyl amino acid modificationGO:00181933360.019
purine ribonucleotide catabolic processGO:00091542080.019
cellular response to cytokine stimulusGO:00713451890.019
regulation of purine nucleotide metabolic processGO:19005421690.019
kidney developmentGO:00018222130.019
cell substrate adhesionGO:00315891300.019
gland developmentGO:00487323300.019
posttranscriptional regulation of gene expressionGO:00106081550.019
positive regulation of nervous system developmentGO:00519622210.019
regulation of protein localizationGO:00328802310.019
action potentialGO:0001508780.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
regulation of cellular component biogenesisGO:00440871810.019
positive regulation of cell developmentGO:00107202370.018
negative regulation of protein modification processGO:00314001630.018
sterol metabolic processGO:0016125580.018
circulatory system processGO:00030131970.018
homeostasis of number of cellsGO:00488722100.018
regulation of cell motilityGO:20001452360.018
protein catabolic processGO:00301632210.018
defense response to bacteriumGO:00427421190.018
protein localization to organelleGO:00333651850.018
neuronal action potentialGO:0019228540.018
ossificationGO:00015032160.018
forebrain developmentGO:00309003020.018
morphogenesis of a branching epitheliumGO:00611381930.018
nucleoside catabolic processGO:00091642060.018
phospholipid metabolic processGO:0006644870.018
reactive oxygen species metabolic processGO:0072593840.018
regulation of body fluid levelsGO:00508781620.018
organophosphate catabolic processGO:00464342320.018
divalent inorganic cation transportGO:00725111780.017
steroid metabolic processGO:00082021190.017
divalent metal ion transportGO:00708381720.017
regulation of cell adhesionGO:00301551540.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
glycoprotein biosynthetic processGO:0009101890.017
multicellular organismal signalingGO:0035637910.017
endomembrane system organizationGO:00102561470.017
positive regulation of programmed cell deathGO:00430682180.017
positive regulation of apoptotic processGO:00430652170.017
ribonucleotide catabolic processGO:00092612080.017
regulation of chloride transportGO:200122520.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
actin cytoskeleton organizationGO:00300362200.017
nucleoside triphosphate catabolic processGO:00091432050.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
cellular macromolecule catabolic processGO:00442652060.017
urogenital system developmentGO:00016552610.017
lymphocyte differentiationGO:00300982420.016
regulation of neuron differentiationGO:00456642810.016
response to inorganic substanceGO:0010035960.016
monocarboxylic acid biosynthetic processGO:0072330610.016
respiratory system developmentGO:00605411900.016
oocyte constructionGO:000730820.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
cytokine productionGO:00018163190.016
spermatogenesisGO:00072832840.016
cellular protein catabolic processGO:00442571550.016
cell junction organizationGO:0034330770.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
negative regulation of cell proliferationGO:00082852960.016
modification dependent protein catabolic processGO:00199411330.016
regulation of secretionGO:00510462740.016
positive regulation of protein kinase activityGO:00458601440.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
response to nutrient levelsGO:00316671090.016
Mouse
male gamete generationGO:00482322850.016
positive regulation of mapk cascadeGO:00434101700.016
cellular ion homeostasisGO:00068731650.016
regulation of nucleotide metabolic processGO:00061401690.016
regulation of neuron projection developmentGO:00109751690.016
negative regulation of cell activationGO:00508661110.015
camera type eye developmentGO:00430102660.015
regulation of protein serine threonine kinase activityGO:00719001570.015
nucleocytoplasmic transportGO:00069131390.015
regulation of transmembrane transportGO:00347621280.015
dephosphorylationGO:00163111290.015
regulation of secretion by cellGO:19035302490.015
nuclear transportGO:00511691390.015
regulation of gtp catabolic processGO:00331241130.015
gtp metabolic processGO:00460391440.015
protein processingGO:00164851630.015
response to organonitrogen compoundGO:00102432460.015
regulation of ion transportGO:00432692150.015
alpha amino acid metabolic processGO:1901605590.015
carbohydrate homeostasisGO:00335001280.015
cholesterol metabolic processGO:0008203560.015
glucose homeostasisGO:00425931280.015
monocarboxylic acid transportGO:0015718440.015
alcohol metabolic processGO:00060661160.015
response to organic cyclic compoundGO:00140701980.015
sulfur compound biosynthetic processGO:0044272370.015
regulation of cytokine productionGO:00018172660.015
stem cell differentiationGO:00488632680.015
positive regulation of transferase activityGO:00513471670.015
leukocyte mediated immunityGO:00024431740.014
oocyte axis specificationGO:000730920.014
respiratory tube developmentGO:00303231670.014
regulation of proteolysisGO:00301621640.014
epithelial cell proliferationGO:00506731740.014
regulation of establishment of protein localizationGO:00702011810.014
cellular response to growth factor stimulusGO:00713631970.014
cellular response to molecule of bacterial originGO:0071219830.014
cellular response to lipopolysaccharideGO:0071222770.014
multicellular organism growthGO:00352641610.014
organelle localizationGO:00516401790.014
positive regulation of kinase activityGO:00336741550.014
regulation of vesicle mediated transportGO:00606271390.014
regulation of nucleoside metabolic processGO:00091181300.014
activation of immune responseGO:00022531380.014
regulation of cellular response to stressGO:00801351590.014
epithelial tube morphogenesisGO:00605623030.014
regulation of purine nucleotide catabolic processGO:00331211220.014
morphogenesis of a branching structureGO:00017632030.014
t cell activationGO:00421102890.014
tissue remodelingGO:00487711020.014
morphogenesis of embryonic epitheliumGO:00163311590.014
heart morphogenesisGO:00030071780.014
epidermis developmentGO:00085441870.014
glycerolipid biosynthetic processGO:0045017500.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
axonogenesisGO:00074092740.013
amino acid transmembrane transportGO:0003333370.013
membrane lipid biosynthetic processGO:0046467320.013
neural precursor cell proliferationGO:00613511210.013
protein localization to nucleusGO:00345041210.013
lung developmentGO:00303241640.013
cellular response to hormone stimulusGO:00328701500.013
myeloid cell differentiationGO:00300992330.013
g protein coupled receptor signaling pathwayGO:00071862430.013
peptidyl tyrosine phosphorylationGO:00181081430.013
lymphocyte mediated immunityGO:00024491390.013
tissue homeostasisGO:00018941150.013
blood vessel morphogenesisGO:00485142850.013
positive regulation of nucleotide metabolic processGO:00459811140.013
regulation of ossificationGO:00302781120.013
regulation of leukocyte differentiationGO:19021051590.013
response to oxidative stressGO:00069791230.013
leukocyte migrationGO:00509001240.013
glycoprotein metabolic processGO:00091001160.013
epithelial cell developmentGO:00020641590.013
regulation of actin filament based processGO:0032970990.013
regulation of system processGO:00440572000.013
hindbrain developmentGO:00309021280.013
regulation of protein catabolic processGO:00421761080.013
response to amino acidGO:0043200370.013
positive regulation of growthGO:00459271040.013
carbohydrate metabolic processGO:00059752300.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
leukocyte proliferationGO:00706611720.013
neutral lipid metabolic processGO:0006638570.013
myeloid cell homeostasisGO:00022621140.013
regulation of cell cycleGO:00517262810.013
dna metabolic processGO:00062593030.013
negative regulation of growthGO:0045926990.013
rna processingGO:00063961050.012
Mouse
hormone secretionGO:00468791280.012
muscle cell differentiationGO:00426922610.012
digestive system developmentGO:00551232000.012
positive regulation of cell activationGO:00508671580.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
regulation of map kinase activityGO:00434051200.012
cellular protein complex assemblyGO:00436231160.012
mrna metabolic processGO:0016071840.012
Mouse
amino acid transportGO:0006865610.012
regulation of nucleotide catabolic processGO:00308111220.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
developmental growth involved in morphogenesisGO:00605601380.012
defense response to other organismGO:00985421970.012
skin developmentGO:00435882200.012
metal ion homeostasisGO:00550651890.012
maintenance of locationGO:0051235890.012
regionalizationGO:00030023370.012
canonical wnt signaling pathwayGO:00600701300.012
adaptive immune responseGO:00022501550.012
developmental maturationGO:00217001930.012
positive regulation of cell motilityGO:20001471160.012
intracellular mrna localizationGO:000829840.012
regulation of intracellular transportGO:00323861590.012
wound healingGO:00420601570.012
negative regulation of cellular component organizationGO:00511291940.012
negative regulation of transferase activityGO:0051348850.012
regulation of ion transmembrane transportGO:00347651190.012
telencephalon developmentGO:00215371860.012
cellular response to biotic stimulusGO:0071216920.012
establishment of protein localization to organelleGO:00725941180.012
regulation of wnt signaling pathwayGO:00301111230.012
positive regulation of neuron differentiationGO:00456661410.012
cell activation involved in immune responseGO:00022631260.012
cellular response to dna damage stimulusGO:00069742070.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
actin filament organizationGO:00070151130.012
single organism nuclear importGO:1902593950.012
tube formationGO:00351481400.012
positive regulation of map kinase activityGO:0043406840.012
sequestering of calcium ionGO:0051208180.012
positive regulation of proteolysisGO:0045862850.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
retinoid metabolic processGO:0001523240.012
compound eye developmentGO:004874910.012
regulation of lymphocyte proliferationGO:00506701170.012
neural tube developmentGO:00219151600.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
microtubule based processGO:00070172360.012
regulation of protein transportGO:00512231630.012
glycerophospholipid metabolic processGO:0006650710.011
fat cell differentiationGO:00454441600.011
proteasomal protein catabolic processGO:0010498980.011
response to light stimulusGO:00094161350.011
response to transforming growth factor betaGO:0071559880.011
negative regulation of kinase activityGO:0033673810.011
acylglycerol metabolic processGO:0006639550.011
cellular alcohol metabolic processGO:004410730.011
regulation of leukocyte proliferationGO:00706631210.011
cellular amino acid biosynthetic processGO:0008652220.011
cytokine mediated signaling pathwayGO:00192211150.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
fatty acid biosynthetic processGO:0006633410.011
regulation of epithelial cell proliferationGO:00506781410.011
guanosine containing compound metabolic processGO:19010681440.011
ear developmentGO:00435832000.011
embryonic epithelial tube formationGO:00018381300.011
divalent inorganic cation homeostasisGO:00725071380.011
skeletal system morphogenesisGO:00487052030.011
positive regulation of gtp catabolic processGO:0033126850.011
regulation of ras protein signal transductionGO:00465781140.011
liver developmentGO:0001889660.011
positive regulation of nucleoside metabolic processGO:0045979910.011
organic hydroxy compound biosynthetic processGO:1901617770.011
hepaticobiliary system developmentGO:0061008670.011
myelinationGO:0042552740.011
t cell proliferationGO:00420981200.011
regulation of protein processingGO:0070613960.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
negative regulation of lymphocyte activationGO:0051250910.011
lymphocyte proliferationGO:00466511640.011
sequestering of metal ionGO:0051238190.011
cognitionGO:00508901490.011
b cell activationGO:00421131610.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
exocytosisGO:00068871210.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
gtp catabolic processGO:00061841430.011
amide transportGO:00428861380.011
organelle fissionGO:00482851700.011
myeloid leukocyte differentiationGO:00025731190.011
organophosphate biosynthetic processGO:00904071220.011
regulation of lymphocyte differentiationGO:00456191070.011
positive regulation of gtpase activityGO:0043547850.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
response to steroid hormoneGO:0048545560.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
negative regulation of cell developmentGO:00107211690.010
phagocytosisGO:0006909660.010
lateral inhibitionGO:004633110.010
synaptic transmissionGO:00072683290.010
cellularizationGO:000734910.010
cell cell adhesionGO:0098609410.010
peptide transportGO:00158331330.010
interleukin 8 productionGO:003263740.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
maternal determination of anterior posterior axis embryoGO:000835820.010
organ regenerationGO:003110020.010
angiogenesisGO:00015252010.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
leukocyte activation involved in immune responseGO:00023661260.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
regulation of cytoskeleton organizationGO:00514931220.010
anatomical structure homeostasisGO:00602491450.010
protein importGO:00170381010.010
mitochondrion organizationGO:00070051340.010
positive regulation of lymphocyte activationGO:00512511400.010
positive regulation of organelle organizationGO:00106381280.010
regulation of bindingGO:00510981110.010
inorganic anion transportGO:0015698430.010
coenzyme metabolic processGO:0006732520.010
gliogenesisGO:00420631410.010
cellular response to acid chemicalGO:0071229680.010
protein targetingGO:00066051430.010
regulation of cytoplasmic transportGO:19036491120.010
regulation of cell substrate adhesionGO:0010810730.010
positive regulation of cellular ph reductionGO:003284920.010
nuclear importGO:0051170950.010

Slc39a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
cancerDOID:16200.020
inherited metabolic disorderDOID:65500.019
immune system diseaseDOID:291400.017
hematopoietic system diseaseDOID:7400.015
sensory system diseaseDOID:005015500.015
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
cardiovascular system diseaseDOID:128700.012
musculoskeletal system diseaseDOID:1700.011