IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Flot2

flotillin 2

(Aliases: reggie-2,Esa,AI573412)

Entrez: 14252
Ensembl: ENSMUSG00000061981
UniProtKB: Q3UEG9
UniProtKB: Q60634
UniProtKB: Q5SS83

Process Predictions
Disease Predictions

Flot2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
membrane organization	GO:0061024	245	0.470	Human Mouse
ras protein signal transduction	GO:0007265	77	0.460	Mouse
cation transport	GO:0006812	399	0.297
protein localization to membrane	GO:0072657	108	0.223	Human Mouse
wound healing	GO:0042060	157	0.212
regulation of intracellular transport	GO:0032386	159	0.212
protein localization to plasma membrane	GO:0072659	57	0.205	Human Mouse
blood circulation	GO:0008015	195	0.184
regulation of multi organism process	GO:0043900	111	0.177
negative regulation of molecular function	GO:0044092	258	0.170
intracellular protein transport	GO:0006886	204	0.155
regulation of protein targeting	GO:1903533	61	0.153
nucleotide metabolic process	GO:0009117	332	0.149
regulation of protein transport	GO:0051223	163	0.140
cellular amine metabolic process	GO:0044106	44	0.137
positive regulation of necrotic cell death	GO:0010940	1	0.131
oxidation reduction process	GO:0055114	342	0.128
regulation of establishment of protein localization	GO:0070201	181	0.128
positive regulation of protein export from nucleus	GO:0046827	4	0.117
regulation of cytoplasmic transport	GO:1903649	112	0.116
negative regulation of phosphate metabolic process	GO:0045936	184	0.114
regulation of secretion	GO:0051046	274	0.114
positive regulation of cell development	GO:0010720	237	0.114
purine ribonucleotide metabolic process	GO:0009150	290	0.106
carbohydrate metabolic process	GO:0005975	230	0.101
inorganic cation transmembrane transport	GO:0098662	207	0.100
cation transmembrane transport	GO:0098655	266	0.099
regulation of cell motility	GO:2000145	236	0.098
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.097
small gtpase mediated signal transduction	GO:0007264	97	0.094	Mouse
cellular homeostasis	GO:0019725	240	0.090
positive regulation of nervous system development	GO:0051962	221	0.087
plasma membrane organization	GO:0007009	90	0.085	Human Mouse
rho protein signal transduction	GO:0007266	32	0.085	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.084
carbohydrate derivative biosynthetic process	GO:1901137	183	0.084
endomembrane system organization	GO:0010256	147	0.083	Human Mouse
regulation of neuron differentiation	GO:0045664	281	0.074
microtubule based process	GO:0007017	236	0.072
regulation of proteolysis	GO:0030162	164	0.072
negative regulation of cellular protein metabolic process	GO:0032269	247	0.070
retina development in camera type eye	GO:0060041	119	0.069
transmembrane transport	GO:0055085	412	0.067
skin development	GO:0043588	220	0.065
camera type eye development	GO:0043010	266	0.065
positive regulation of cellular amine metabolic process	GO:0033240	5	0.065
negative regulation of protein metabolic process	GO:0051248	282	0.064	Human
circulatory system process	GO:0003013	197	0.064
cytoplasmic transport	GO:0016482	234	0.063
response to ischemia	GO:0002931	14	0.063
heart contraction	GO:0060047	93	0.062
protein localization to organelle	GO:0033365	185	0.062
regulation of intracellular protein transport	GO:0033157	82	0.062
establishment of protein localization to organelle	GO:0072594	118	0.061
protein processing	GO:0016485	163	0.061
regulation of response to wounding	GO:1903034	189	0.060
negative regulation of phosphorylation	GO:0042326	166	0.060
positive regulation of neuron differentiation	GO:0045666	141	0.059
nuclear transport	GO:0051169	139	0.058
regulation of secretion by cell	GO:1903530	249	0.058
calcium ion transport	GO:0006816	159	0.058
calcium ion homeostasis	GO:0055074	127	0.058
amine metabolic process	GO:0009308	45	0.057
mapk cascade	GO:0000165	281	0.057
nucleobase containing small molecule metabolic process	GO:0055086	352	0.056
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.056
positive regulation of cell motility	GO:2000147	116	0.056
nucleocytoplasmic transport	GO:0006913	139	0.056
locomotory behavior	GO:0007626	195	0.056
central nervous system neuron differentiation	GO:0021953	162	0.055
epidermis development	GO:0008544	187	0.054
response to oxidative stress	GO:0006979	123	0.054
positive regulation of apoptotic process	GO:0043065	217	0.054
establishment of protein localization to plasma membrane	GO:0090002	34	0.054	Human
energy derivation by oxidation of organic compounds	GO:0015980	77	0.054
regulation of ion transport	GO:0043269	215	0.053
mitochondrion organization	GO:0007005	134	0.052
nucleoside phosphate metabolic process	GO:0006753	338	0.052
meiotic cell cycle	GO:0051321	122	0.051
positive regulation of secretion by cell	GO:1903532	114	0.051
establishment or maintenance of cell polarity	GO:0007163	86	0.051
divalent inorganic cation transport	GO:0072511	178	0.050
anion transport	GO:0006820	177	0.050
cellular amino acid metabolic process	GO:0006520	103	0.050
cellular response to growth factor stimulus	GO:0071363	197	0.050
respiratory system development	GO:0060541	190	0.050
negative regulation of intracellular signal transduction	GO:1902532	167	0.050
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.049
synaptic transmission	GO:0007268	329	0.048
activation of adenylate cyclase activity	GO:0007190	4	0.048
regulation of metal ion transport	GO:0010959	106	0.048
axonogenesis	GO:0007409	274	0.048	Mouse
regulation of system process	GO:0044057	200	0.048
carbohydrate homeostasis	GO:0033500	128	0.047
energy reserve metabolic process	GO:0006112	39	0.047
smoothened signaling pathway	GO:0007224	105	0.047
response to radiation	GO:0009314	165	0.047
regulation of cell cycle	GO:0051726	281	0.046
cellular glucan metabolic process	GO:0006073	32	0.046
developmental maturation	GO:0021700	193	0.046
regulation of cellular ketone metabolic process	GO:0010565	66	0.045
t cell activation	GO:0042110	289	0.045
transmission of nerve impulse	GO:0019226	76	0.045
positive regulation of mapk cascade	GO:0043410	170	0.045
organic anion transport	GO:0015711	137	0.045
polysaccharide metabolic process	GO:0005976	39	0.044
epithelial tube morphogenesis	GO:0060562	303	0.044
regulation of body fluid levels	GO:0050878	162	0.044
positive regulation of cell projection organization	GO:0031346	95	0.044
regulation of meiotic cell cycle	GO:0051445	34	0.044
cellular metal ion homeostasis	GO:0006875	151	0.043
cellular ketone metabolic process	GO:0042180	84	0.043
ensheathment of neurons	GO:0007272	76	0.043
extracellular matrix organization	GO:0030198	147	0.043
regulation of cell migration	GO:0030334	219	0.043
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.043
protein maturation	GO:0051604	176	0.042
cell maturation	GO:0048469	127	0.042
negative regulation of phosphorus metabolic process	GO:0010563	184	0.041
cell type specific apoptotic process	GO:0097285	268	0.041
protein import into nucleus	GO:0006606	95	0.041
neuronal action potential	GO:0019228	54	0.040
maintenance of location	GO:0051235	89	0.040
cell junction organization	GO:0034330	77	0.040
ion transmembrane transport	GO:0034220	361	0.040
regulation of protein binding	GO:0043393	60	0.040
positive regulation of cell cycle	GO:0045787	92	0.040
establishment of endothelial blood brain barrier	GO:0014045	3	0.040
protein import	GO:0017038	101	0.039
action potential	GO:0001508	78	0.039
negative regulation of protein phosphorylation	GO:0001933	126	0.039
positive regulation of neuron projection development	GO:0010976	79	0.039
generation of precursor metabolites and energy	GO:0006091	103	0.039
positive regulation of endopeptidase activity	GO:0010950	43	0.038
glycoprotein biosynthetic process	GO:0009101	89	0.038
cellular protein catabolic process	GO:0044257	155	0.038
protein ubiquitination	GO:0016567	171	0.038
organelle localization	GO:0051640	179	0.037
divalent inorganic cation homeostasis	GO:0072507	138	0.037
macromolecule catabolic process	GO:0009057	281	0.037
regulation of nucleocytoplasmic transport	GO:0046822	73	0.036
positive regulation of protein transport	GO:0051222	93	0.036
response to lipopolysaccharide	GO:0032496	128	0.036
detection of abiotic stimulus	GO:0009582	60	0.036
inorganic ion transmembrane transport	GO:0098660	234	0.036
regulation of protein localization	GO:0032880	231	0.035
positive regulation of proteolysis	GO:0045862	85	0.035
cellular carbohydrate metabolic process	GO:0044262	119	0.035
visual perception	GO:0007601	52	0.035
cell growth	GO:0016049	130	0.034
regulation of kinase activity	GO:0043549	249	0.034
dephosphorylation	GO:0016311	129	0.034
positive regulation of innate immune response	GO:0045089	80	0.034
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.034
epithelial cell proliferation	GO:0050673	174	0.034
negative regulation of protein transport	GO:0051224	46	0.034
glycogen metabolic process	GO:0005977	32	0.034
innate immune response	GO:0045087	157	0.034
development of primary sexual characteristics	GO:0045137	143	0.034
axon ensheathment	GO:0008366	76	0.033
regulation of wound healing	GO:0061041	40	0.033
regulation of heart contraction	GO:0008016	77	0.033
regulation of membrane potential	GO:0042391	192	0.033
anatomical structure homeostasis	GO:0060249	145	0.033
regulation of peptidase activity	GO:0052547	96	0.033
sensory perception	GO:0007600	245	0.032
peptidyl serine modification	GO:0018209	83	0.032
macroautophagy	GO:0016236	21	0.032
nuclear import	GO:0051170	95	0.032
asymmetric neuroblast division	GO:0055059	1	0.032
g protein coupled receptor signaling pathway	GO:0007186	243	0.032
positive regulation of protein modification process	GO:0031401	299	0.032
protein targeting	GO:0006605	143	0.032
ossification	GO:0001503	216	0.031
positive regulation of secretion	GO:0051047	130	0.031
inflammatory response	GO:0006954	244	0.031
cellular polysaccharide metabolic process	GO:0044264	38	0.031
positive regulation of cell migration	GO:0030335	109	0.030
regulation of defense response	GO:0031347	233	0.030
multicellular organismal signaling	GO:0035637	91	0.030
hemostasis	GO:0007599	78	0.030
regulation of ion transmembrane transport	GO:0034765	119	0.030
metal ion homeostasis	GO:0055065	189	0.030
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.030
protein modification by small protein conjugation	GO:0032446	187	0.029
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.029
cellular chemical homeostasis	GO:0055082	215	0.029
positive regulation of cell death	GO:0010942	224	0.029
retina morphogenesis in camera type eye	GO:0060042	45	0.029
sterol homeostasis	GO:0055092	45	0.029
single organism nuclear import	GO:1902593	95	0.029
embryonic appendage morphogenesis	GO:0035113	126	0.029
establishment of protein localization to membrane	GO:0090150	54	0.028	Human
vacuole organization	GO:0007033	38	0.028
glucan metabolic process	GO:0044042	32	0.028
endocytosis	GO:0006897	168	0.027
cellular ion homeostasis	GO:0006873	165	0.027
heart process	GO:0003015	94	0.027
cilium morphogenesis	GO:0060271	102	0.027
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.027
cholesterol homeostasis	GO:0042632	44	0.027
regulation of binding	GO:0051098	111	0.027
regulation of protein maturation	GO:1903317	96	0.027
regulation of protein kinase activity	GO:0045859	232	0.027
cell substrate adhesion	GO:0031589	130	0.026
sulfur compound metabolic process	GO:0006790	100	0.026
response to light stimulus	GO:0009416	135	0.026
blood coagulation	GO:0007596	76	0.026
regulation of lymphocyte activation	GO:0051249	240	0.026
sensory perception of light stimulus	GO:0050953	54	0.026
organelle fission	GO:0048285	170	0.026
regulation of anatomical structure size	GO:0090066	178	0.026
protein catabolic process	GO:0030163	221	0.026
regulation of calcium ion transport	GO:0051924	69	0.026
sodium ion transport	GO:0006814	73	0.026
single organismal cell cell adhesion	GO:0016337	131	0.026
response to organic cyclic compound	GO:0014070	198	0.026
nitrogen compound transport	GO:0071705	271	0.025
establishment of organelle localization	GO:0051656	122	0.025
cognition	GO:0050890	149	0.025
regulation of cellular amino acid metabolic process	GO:0006521	5	0.025
glucose homeostasis	GO:0042593	128	0.025
appendage morphogenesis	GO:0035107	149	0.025
neuron projection extension	GO:1990138	64	0.025
organonitrogen compound biosynthetic process	GO:1901566	192	0.024
positive regulation of hormone secretion	GO:0046887	38	0.024
metencephalon development	GO:0022037	89	0.024
negative regulation of intracellular transport	GO:0032387	38	0.024
lipid biosynthetic process	GO:0008610	179	0.024
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.024
positive regulation of response to wounding	GO:1903036	66	0.024
skeletal system development	GO:0001501	356	0.024
apoptotic signaling pathway	GO:0097190	306	0.024
regulation of calcium ion transport into cytosol	GO:0010522	31	0.024
cellular response to lipopolysaccharide	GO:0071222	77	0.024
cellular macromolecule catabolic process	GO:0044265	206	0.024
peptide transport	GO:0015833	133	0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.024
purine ribonucleotide catabolic process	GO:0009154	208	0.024
learning or memory	GO:0007611	148	0.024
regulation of erk1 and erk2 cascade	GO:0070372	71	0.024
regulation of cellular amine metabolic process	GO:0033238	20	0.024
cellular response to hormone stimulus	GO:0032870	150	0.023
regulation of cyclic nucleotide metabolic process	GO:0030799	40	0.023
coagulation	GO:0050817	78	0.023
regulation of hormone levels	GO:0010817	211	0.023
retinal cone cell development	GO:0046549	8	0.023
dna metabolic process	GO:0006259	303	0.023
peptidyl tyrosine modification	GO:0018212	145	0.023
dendrite development	GO:0016358	115	0.023
cellular response to glucose stimulus	GO:0071333	45	0.023
molting cycle	GO:0042303	90	0.023
cellular response to hexose stimulus	GO:0071331	47	0.023
response to growth factor	GO:0070848	198	0.023
regulation of blood circulation	GO:1903522	93	0.023
lipid transport	GO:0006869	98	0.023
lipid localization	GO:0010876	126	0.023
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.023
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.023
cell cell junction organization	GO:0045216	72	0.023
regulation of protein localization to nucleus	GO:1900180	60	0.023
cell fate commitment	GO:0045165	210	0.023
cartilage development	GO:0051216	140	0.023
regulation of mapk cascade	GO:0043408	248	0.023
response to fibroblast growth factor	GO:0071774	47	0.023
embryonic limb morphogenesis	GO:0030326	126	0.023
organic hydroxy compound transport	GO:0015850	93	0.023
sensory perception of umami taste	GO:0050917	4	0.023
cellular response to extracellular stimulus	GO:0031668	81	0.022
cellular response to oxidative stress	GO:0034599	76	0.022
cellular glucose homeostasis	GO:0001678	52	0.022
regulation of camp metabolic process	GO:0030814	30	0.022
nucleoside phosphate catabolic process	GO:1901292	222	0.022
regulation of cell adhesion	GO:0030155	154	0.022
regulation of cellular component size	GO:0032535	121	0.022
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.022
protein modification by small protein conjugation or removal	GO:0070647	207	0.022
negative regulation of neuron apoptotic process	GO:0043524	92	0.022
regulation of endopeptidase activity	GO:0052548	89	0.022
cell adhesion	GO:0007155	329	0.022
g1 s transition of mitotic cell cycle	GO:0000082	57	0.022
epithelial cell development	GO:0002064	159	0.022
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.022
positive regulation of defense response	GO:0031349	124	0.022
placenta development	GO:0001890	140	0.022
positive regulation of peptidase activity	GO:0010952	49	0.022
mitotic cell cycle	GO:0000278	195	0.021
regulation of hydrolase activity	GO:0051336	246	0.021
syncytium formation by plasma membrane fusion	GO:0000768	42	0.021
positive regulation of programmed cell death	GO:0043068	218	0.021
regulation of hemostasis	GO:1900046	28	0.021
cyclic nucleotide metabolic process	GO:0009187	59	0.021
negative regulation of organelle organization	GO:0010639	90	0.021
peptide hormone secretion	GO:0030072	109	0.021
divalent metal ion transport	GO:0070838	172	0.021
negative regulation of protein localization to nucleus	GO:1900181	23	0.021
regulation of cell growth	GO:0001558	91	0.021
positive regulation of kinase activity	GO:0033674	155	0.021
negative regulation of nucleocytoplasmic transport	GO:0046823	23	0.021
cell cycle switching	GO:0060184	1	0.021
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.021
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.021
erk1 and erk2 cascade	GO:0070371	77	0.021
pigmentation	GO:0043473	71	0.021
multicellular organism growth	GO:0035264	161	0.021
negative regulation of growth	GO:0045926	99	0.021
regulation of protein processing	GO:0070613	96	0.021
organelle assembly	GO:0070925	177	0.021
leukocyte migration	GO:0050900	124	0.021
regulation of leukocyte differentiation	GO:1902105	159	0.020
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.020
purine nucleotide biosynthetic process	GO:0006164	65	0.020
forebrain neuron differentiation	GO:0021879	52	0.020
positive regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0035774	13	0.020
cellular amide metabolic process	GO:0043603	58	0.020
multicellular organismal homeostasis	GO:0048871	164	0.020
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.020
lung development	GO:0030324	164	0.020
nucleotide biosynthetic process	GO:0009165	78	0.020
aromatic compound catabolic process	GO:0019439	286	0.020
regulation of synaptic plasticity	GO:0048167	87	0.020
ubiquitin dependent protein catabolic process	GO:0006511	129	0.020
myelination	GO:0042552	74	0.020
posttranscriptional regulation of gene expression	GO:0010608	155	0.020	Human
negative regulation of transcription factor import into nucleus	GO:0042992	13	0.020
positive regulation of camp metabolic process	GO:0030816	19	0.020
positive regulation of protein phosphorylation	GO:0001934	242	0.020
detection of stimulus	GO:0051606	84	0.020
regulation of exocytosis	GO:0017157	61	0.020
appendage development	GO:0048736	166	0.020
positive regulation of intracellular protein transport	GO:0090316	42	0.020
calcium ion transmembrane transport	GO:0070588	85	0.020
organic acid biosynthetic process	GO:0016053	86	0.020
hindbrain development	GO:0030902	128	0.019
stem cell proliferation	GO:0072089	117	0.019
regulation of cell projection organization	GO:0031344	206	0.019
response to molecule of bacterial origin	GO:0002237	143	0.019
insulin secretion involved in cellular response to glucose stimulus	GO:0035773	36	0.019
muscle cell differentiation	GO:0042692	261	0.019
endothelial cell differentiation	GO:0045446	41	0.019
photoreceptor cell development	GO:0042461	40	0.019
establishment of melanosome localization	GO:0032401	11	0.019
peptidyl amino acid modification	GO:0018193	336	0.019
fibroblast growth factor receptor signaling pathway	GO:0008543	46	0.019
respiratory tube development	GO:0030323	167	0.019
endothelium development	GO:0003158	45	0.019
response to osmotic stress	GO:0006970	21	0.019
sensory organ morphogenesis	GO:0090596	242	0.019
interspecies interaction between organisms	GO:0044419	83	0.019
ameboidal type cell migration	GO:0001667	128	0.019
multi organism behavior	GO:0051705	62	0.019
regulation of neuron death	GO:1901214	134	0.019
limb morphogenesis	GO:0035108	149	0.019
regulation of innate immune response	GO:0045088	91	0.019
intracellular mrna localization	GO:0008298	4	0.019
immune effector process	GO:0002252	321	0.019
regionalization	GO:0003002	337	0.019
immune response regulating signaling pathway	GO:0002764	125	0.018
positive regulation of protein kinase activity	GO:0045860	144	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.018
sequestering of calcium ion	GO:0051208	18	0.018
regulation of cellular response to stress	GO:0080135	159	0.018
positive regulation of fibroblast growth factor receptor signaling pathway	GO:0045743	3	0.018
eye photoreceptor cell differentiation	GO:0001754	41	0.018
organic hydroxy compound metabolic process	GO:1901615	203	0.018
response to hepatocyte growth factor	GO:0035728	2	0.018
positive regulation of dendrite development	GO:1900006	21	0.018
regulation of cell cycle process	GO:0010564	160	0.018
negative regulation of intracellular protein transport	GO:0090317	27	0.018
regulation of feeding behavior	GO:0060259	3	0.018
cerebellum development	GO:0021549	77	0.018
regulation of peptide transport	GO:0090087	91	0.018
regulation of organelle organization	GO:0033043	289	0.018
nucleoside catabolic process	GO:0009164	206	0.018
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.018
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.018
regulation of neuron apoptotic process	GO:0043523	122	0.018
photoreceptor cell differentiation	GO:0046530	52	0.018
connective tissue development	GO:0061448	179	0.018
detection of external stimulus	GO:0009581	61	0.017
cellular response to lipid	GO:0071396	145	0.017
regulation of epithelial cell proliferation	GO:0050678	141	0.017
protein localization to nucleus	GO:0034504	121	0.017
purine ribonucleoside metabolic process	GO:0046128	241	0.017
leukocyte differentiation	GO:0002521	342	0.017
multi multicellular organism process	GO:0044706	109	0.017
regulation of transcription factor import into nucleus	GO:0042990	24	0.017
tube formation	GO:0035148	140	0.017
regulation of peptide hormone secretion	GO:0090276	75	0.017
regulation of cell activation	GO:0050865	289	0.017
embryonic digit morphogenesis	GO:0042733	56	0.017
purine containing compound biosynthetic process	GO:0072522	70	0.017
striated muscle contraction	GO:0006941	45	0.017
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.017
response to monosaccharide	GO:0034284	67	0.017
regulation of nucleotide biosynthetic process	GO:0030808	34	0.017
positive regulation of intracellular transport	GO:0032388	70	0.017
negative regulation of cell proliferation	GO:0008285	296	0.017
negative regulation of protein modification process	GO:0031400	163	0.017
regulation of cellular protein catabolic process	GO:1903362	61	0.017
ear development	GO:0043583	200	0.017
ribose phosphate metabolic process	GO:0019693	291	0.017
central nervous system neuron development	GO:0021954	67	0.017
insulin secretion	GO:0030073	89	0.017
skeletal system morphogenesis	GO:0048705	203	0.017
peptide secretion	GO:0002790	114	0.017
maintenance of location in cell	GO:0051651	24	0.016
regulation of t cell activation	GO:0050863	170	0.016
modification dependent macromolecule catabolic process	GO:0043632	133	0.016
nucleoside phosphate biosynthetic process	GO:1901293	79	0.016
thermosensory behavior	GO:0040040	1	0.016
negative regulation of cytoplasmic transport	GO:1903650	29	0.016
forebrain neuron development	GO:0021884	30	0.016
regulation of blood coagulation	GO:0030193	28	0.016
kidney development	GO:0001822	213	0.016
carboxylic acid transport	GO:0046942	100	0.016
stem cell differentiation	GO:0048863	268	0.016
carbohydrate biosynthetic process	GO:0016051	74	0.016
microtubule cytoskeleton organization	GO:0000226	157	0.016
methylation	GO:0032259	134	0.016
regulation of cell size	GO:0008361	72	0.016
cell matrix adhesion	GO:0007160	68	0.016
muscle system process	GO:0003012	141	0.015
extracellular structure organization	GO:0043062	148	0.015
protein glycosylation	GO:0006486	55	0.015
negative regulation of mitotic cell cycle	GO:0045930	58	0.015
regulation of purine nucleotide metabolic process	GO:1900542	169	0.015
carboxylic acid biosynthetic process	GO:0046394	86	0.015
response to reactive oxygen species	GO:0000302	56	0.015
cellular response to acid chemical	GO:0071229	68	0.015
myeloid cell differentiation	GO:0030099	233	0.015
cilium assembly	GO:0042384	81	0.015
cell chemotaxis	GO:0060326	81	0.015
regulation of osteoblast differentiation	GO:0045667	67	0.015
cellular lipid metabolic process	GO:0044255	323	0.015
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.015
cation homeostasis	GO:0055080	212	0.015
regulation of protein serine threonine kinase activity	GO:0071900	157	0.015
embryonic skeletal system development	GO:0048706	120	0.015
cellular response to carbohydrate stimulus	GO:0071322	50	0.015
regulation of neuron projection development	GO:0010975	169	0.015
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.015
negative regulation of transposition	GO:0010529	2	0.015
apical junction assembly	GO:0043297	15	0.015
neural tube development	GO:0021915	160	0.015
cyclic purine nucleotide metabolic process	GO:0052652	43	0.015
regulation of ras protein signal transduction	GO:0046578	114	0.015	Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.015
establishment of glial blood brain barrier	GO:0060857	2	0.015
cellular response to fibroblast growth factor stimulus	GO:0044344	47	0.015
amide transport	GO:0042886	138	0.015
response to extracellular stimulus	GO:0009991	127	0.015
lipid homeostasis	GO:0055088	63	0.014
cholesterol transport	GO:0030301	38	0.014
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.014
meiotic nuclear division	GO:0007126	115	0.014
regulation of protein catabolic process	GO:0042176	108	0.014
hormone secretion	GO:0046879	128	0.014
substrate adhesion dependent cell spreading	GO:0034446	30	0.014
cellular modified amino acid metabolic process	GO:0006575	63	0.014
positive regulation of cytoplasmic transport	GO:1903651	40	0.014
establishment of vesicle localization	GO:0051650	81	0.014
regulation of transmembrane transport	GO:0034762	128	0.014
regulation of ossification	GO:0030278	112	0.014
leukocyte proliferation	GO:0070661	172	0.014
negative regulation of cellular amine metabolic process	GO:0033239	1	0.014
cellular response to abiotic stimulus	GO:0071214	56	0.014
extrinsic apoptotic signaling pathway	GO:0097191	126	0.014
autophagy	GO:0006914	45	0.014
defense response to other organism	GO:0098542	197	0.014
negative regulation of homeostatic process	GO:0032845	71	0.014
cellular response to molecule of bacterial origin	GO:0071219	83	0.014
embryonic placenta development	GO:0001892	98	0.014
carbohydrate catabolic process	GO:0016052	32	0.014
regulation of cellular component biogenesis	GO:0044087	181	0.014
cellular response to nutrient levels	GO:0031669	64	0.014
receptor mediated endocytosis	GO:0006898	51	0.014
carbon catabolite activation of transcription	GO:0045991	4	0.014
protein autophosphorylation	GO:0046777	61	0.014
cellular response to biotic stimulus	GO:0071216	92	0.014
negative regulation of endopeptidase activity	GO:0010951	44	0.013
response to inorganic substance	GO:0010035	96	0.013
regulation of chromosome organization	GO:0033044	83	0.013
positive regulation of peptide secretion	GO:0002793	33	0.013
g protein coupled acetylcholine receptor signaling pathway	GO:0007213	4	0.013
mitotic cell cycle process	GO:1903047	159	0.013
positive regulation of growth	GO:0045927	104	0.013
limb development	GO:0060173	166	0.013
developmental cell growth	GO:0048588	84	0.013
glycoprotein metabolic process	GO:0009100	116	0.013
regulation of chromatin modification	GO:1903308	57	0.013
adult behavior	GO:0030534	135	0.013
activation of immune response	GO:0002253	138	0.013

Flot2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.071
musculoskeletal system disease	DOID:17	0.042
disease of anatomical entity	DOID:7	0.042
acquired metabolic disease	DOID:0060158	0.016
inherited metabolic disorder	DOID:655	0.014

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