Mus musculus

16 known processes

Pias3

protein inhibitor of activated STAT 3

(Aliases: MGC27936,Pias3l)

Pias3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517262810.137
Fly
skeletal system developmentGO:00015013560.135
ribonucleoside triphosphate metabolic processGO:00091992200.132
membrane organizationGO:00610242450.121
dna metabolic processGO:00062593030.106
Fly
protein localization to organelleGO:00333651850.097
cellular response to lipopolysaccharideGO:0071222770.095
positive regulation of apoptotic processGO:00430652170.095
Mouse
gland developmentGO:00487323300.094
aromatic compound catabolic processGO:00194392860.093
organonitrogen compound catabolic processGO:19015652640.093
skin developmentGO:00435882200.092
response to lipopolysaccharideGO:00324961280.085
nucleoside phosphate metabolic processGO:00067533380.081
peptidyl amino acid modificationGO:00181933360.081
heterocycle catabolic processGO:00467002800.078
response to molecule of bacterial originGO:00022371430.078
regulation of intracellular transportGO:00323861590.078
protein localization to nucleusGO:00345041210.078
synaptic transmissionGO:00072683290.077
protein targetingGO:00066051430.077
macromolecule catabolic processGO:00090572810.074
Mouse
ras protein signal transductionGO:0007265770.068
nucleobase containing small molecule metabolic processGO:00550863520.065
cellular response to molecule of bacterial originGO:0071219830.064
purine nucleotide metabolic processGO:00061633020.064
nucleoside catabolic processGO:00091642060.063
cellular response to biotic stimulusGO:0071216920.062
protein import into nucleusGO:0006606950.061
regulation of cellular ketone metabolic processGO:0010565660.060
glycosyl compound metabolic processGO:19016572460.060
positive regulation of cellular amino acid metabolic processGO:004576430.059
nucleoside triphosphate metabolic processGO:00091412300.058
intracellular protein transportGO:00068862040.058
protein importGO:00170381010.058
nitrogen compound transportGO:00717052710.058
purine nucleoside triphosphate metabolic processGO:00091442260.057
nucleotide metabolic processGO:00091173320.056
gtp catabolic processGO:00061841430.056
methylationGO:00322591340.055
regulation of sequence specific dna binding transcription factor activityGO:00510901060.055
Mouse
sulfur compound biosynthetic processGO:0044272370.054
positive regulation of gtpase activityGO:0043547850.054
cellular nitrogen compound catabolic processGO:00442702800.053
vesicle localizationGO:0051648860.052
positive regulation of innate immune responseGO:0045089800.051
Fly
nucleoside triphosphate catabolic processGO:00091432050.050
organic cyclic compound catabolic processGO:19013612950.050
purine ribonucleoside triphosphate catabolic processGO:00092071990.049
guanosine containing compound metabolic processGO:19010681440.049
purine nucleotide catabolic processGO:00061952110.049
maintenance of locationGO:0051235890.047
organophosphate catabolic processGO:00464342320.047
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.047
guanosine containing compound catabolic processGO:19010691440.047
rho protein signal transductionGO:0007266320.046
chromatin organizationGO:00063252060.046
positive regulation of apoptotic signaling pathwayGO:2001235950.046
Mouse
epidermis developmentGO:00085441870.046
cellular response to dna damage stimulusGO:00069742070.046
Mouse Fly
myeloid cell differentiationGO:00300992330.046
purine ribonucleotide metabolic processGO:00091502900.045
cell fate commitmentGO:00451652100.045
regulation of protein transportGO:00512231630.043
organonitrogen compound biosynthetic processGO:19015661920.043
nuclear importGO:0051170950.043
blood circulationGO:00080151950.042
regulation of reactive oxygen species biosynthetic processGO:190342620.042
regionalizationGO:00030023370.041
male gamete generationGO:00482322850.041
small gtpase mediated signal transductionGO:0007264970.041
positive regulation of protein modification processGO:00314012990.041
Human
purine nucleoside metabolic processGO:00422782410.040
nucleoside metabolic processGO:00091162460.040
regulation of neuron differentiationGO:00456642810.040
negative regulation of cell cycleGO:00457861230.039
Fly
purine containing compound catabolic processGO:00725232130.039
embryonic organ morphogenesisGO:00485622760.039
cellular response to lipidGO:00713961450.039
cytoplasmic transportGO:00164822340.038
regulation of establishment of protein localizationGO:00702011810.037
ossificationGO:00015032160.037
Mouse
response to light stimulusGO:00094161350.037
cellular amino acid metabolic processGO:00065201030.037
positive regulation of programmed cell deathGO:00430682180.037
Mouse
regulation of bindingGO:00510981110.036
nucleotide catabolic processGO:00091662170.035
proteolysis involved in cellular protein catabolic processGO:00516031470.035
Mouse
purine ribonucleoside catabolic processGO:00461302050.035
regulation of cellular component biogenesisGO:00440871810.035
positive regulation of cellular amine metabolic processGO:003324050.035
purine ribonucleotide catabolic processGO:00091542080.035
microtubule based processGO:00070172360.035
chemotaxisGO:00069352470.035
purine containing compound metabolic processGO:00725213110.034
positive regulation of protein phosphorylationGO:00019342420.034
spermatogenesisGO:00072832840.034
regulation of nucleotide metabolic processGO:00061401690.034
carbohydrate derivative catabolic processGO:19011362310.034
cellular protein catabolic processGO:00442571550.033
Mouse
regulation of protein localizationGO:00328802310.033
establishment of organelle localizationGO:00516561220.033
nuclear transportGO:00511691390.032
carbohydrate derivative biosynthetic processGO:19011371830.032
establishment of vesicle localizationGO:0051650810.032
regulation of purine nucleotide metabolic processGO:19005421690.032
regulation of intracellular protein transportGO:0033157820.032
regulation of protein serine threonine kinase activityGO:00719001570.032
ribonucleoside catabolic processGO:00424542060.032
cell cycle arrestGO:0007050370.032
histone modificationGO:00165701590.031
regulation of vesicle mediated transportGO:00606271390.031
response to organic cyclic compoundGO:00140701980.031
protein catabolic processGO:00301632210.030
Mouse
positive regulation of cell deathGO:00109422240.030
Mouse
respiratory tube developmentGO:00303231670.029
glycosyl compound catabolic processGO:19016582060.029
regulation of cell migrationGO:00303342190.029
kidney developmentGO:00018222130.029
ribonucleotide metabolic processGO:00092592910.029
muscle tissue developmentGO:00605373080.029
purine nucleoside triphosphate catabolic processGO:00091462030.029
chromatin modificationGO:00165681870.028
stem cell maintenanceGO:00198271300.028
synaptic vesicle localizationGO:0097479590.028
protein modification by small protein conjugation or removalGO:00706472070.028
positive regulation of hydrolase activityGO:00513451480.028
cellular amine metabolic processGO:0044106440.028
negative regulation of cellular component organizationGO:00511291940.028
protein maturationGO:00516041760.028
positive regulation of reactive oxygen species biosynthetic processGO:190342820.028
defense response to bacteriumGO:00427421190.028
Fly
regulation of cellular component sizeGO:00325351210.027
lung developmentGO:00303241640.027
regulation of organelle organizationGO:00330432890.027
lateral inhibitionGO:004633110.027
reactive oxygen species biosynthetic processGO:190340980.027
regulation of cytoplasmic transportGO:19036491120.027
nucleocytoplasmic transportGO:00069131390.026
purine ribonucleoside metabolic processGO:00461282410.026
ribonucleoside triphosphate catabolic processGO:00092031990.026
positive regulation of reactive oxygen species metabolic processGO:2000379110.026
positive regulation of protein serine threonine kinase activityGO:00719021060.026
regulation of system processGO:00440572000.026
cation transmembrane transportGO:00986552660.026
Rat
ribose phosphate metabolic processGO:00196932910.026
positive regulation of kinase activityGO:00336741550.026
embryonic limb morphogenesisGO:00303261260.026
proteasomal protein catabolic processGO:0010498980.026
Mouse
response to oxidative stressGO:00069791230.026
glycoprotein biosynthetic processGO:0009101890.026
regulation of transferase activityGO:00513382630.025
ion transmembrane transportGO:00342203610.025
Rat
positive regulation of cellular catabolic processGO:00313311480.025
Mouse
carbohydrate biosynthetic processGO:0016051740.025
positive regulation of transferase activityGO:00513471670.025
gtp metabolic processGO:00460391440.025
hematopoietic progenitor cell differentiationGO:00022441430.025
endomembrane system organizationGO:00102561470.025
regulation of membrane potentialGO:00423911920.025
Rat
regulation of nucleotide catabolic processGO:00308111220.024
retrograde transport endosome to golgiGO:004214720.024
regulation of hydrolase activityGO:00513362460.024
positive regulation of nucleoside metabolic processGO:0045979910.024
striated muscle contractionGO:0006941450.024
regulation of rho gtpase activityGO:0032319580.024
developmental maturationGO:00217001930.024
single organism nuclear importGO:1902593950.024
organelle assemblyGO:00709251770.024
establishment of protein localization to organelleGO:00725941180.024
t cell activationGO:00421102890.024
cell cycle g1 s phase transitionGO:0044843570.023
stem cell differentiationGO:00488632680.023
regulation of proteolysisGO:00301621640.023
Mouse
embryonic appendage morphogenesisGO:00351131260.023
establishment or maintenance of cell polarityGO:0007163860.023
macromolecule methylationGO:00434141200.023
protein processingGO:00164851630.023
regulation of mitotic cell cycleGO:00073461260.023
Fly
rhythmic processGO:00485111740.023
multi organism behaviorGO:0051705620.023
positive regulation of nervous system developmentGO:00519622210.023
nucleoside phosphate catabolic processGO:19012922220.023
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
regulation of protein targetingGO:1903533610.022
regulation of multi organism processGO:00439001110.022
ribonucleotide catabolic processGO:00092612080.022
purine nucleoside catabolic processGO:00061522050.022
regulation of purine nucleotide catabolic processGO:00331211220.022
regulation of cell cycle processGO:00105641600.022
Fly
epithelial cell proliferationGO:00506731740.022
peptidyl lysine modificationGO:0018205770.022
reactive nitrogen species metabolic processGO:200105700.022
vesicle organizationGO:0016050600.022
positive regulation of defense responseGO:00313491240.022
Fly
angiogenesisGO:00015252010.022
multicellular organismal homeostasisGO:00488711640.022
translationGO:0006412930.022
regulation of leukocyte differentiationGO:19021051590.021
protein acylationGO:0043543640.021
activation of immune responseGO:00022531380.021
axonogenesisGO:00074092740.021
erk1 and erk2 cascadeGO:0070371770.021
protein localization to membraneGO:00726571080.021
cellular response to cytokine stimulusGO:00713451890.021
establishment of protein localization to membraneGO:0090150540.021
meiotic cell cycleGO:00513211220.021
cartilage developmentGO:00512161400.021
production of molecular mediator of immune responseGO:00024401030.021
multi multicellular organism processGO:00447061090.020
regulation of synaptic growth at neuromuscular junctionGO:000858240.020
glycoprotein metabolic processGO:00091001160.020
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.020
regulation of erk1 and erk2 cascadeGO:0070372710.020
wnt signaling pathwayGO:00160551880.020
defense response to other organismGO:00985421970.020
Fly
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
modification dependent macromolecule catabolic processGO:00436321330.020
Mouse
macromolecular complex disassemblyGO:0032984430.020
gastrulationGO:00073691160.020
sulfur compound metabolic processGO:00067901000.020
carbohydrate metabolic processGO:00059752300.019
negative regulation of cytoskeleton organizationGO:0051494360.019
negative regulation of organelle organizationGO:0010639900.019
regulation of protein kinase activityGO:00458592320.019
cellular response to fluid shear stressGO:007149840.019
regulation of protein localization to nucleusGO:1900180600.019
cellular ketone metabolic processGO:0042180840.019
skeletal system morphogenesisGO:00487052030.019
negative regulation of nervous system developmentGO:00519611560.019
regulation of myeloid cell differentiationGO:0045637960.019
regulation of cellular amine metabolic processGO:0033238200.019
regulation of cellular catabolic processGO:00313292420.018
Mouse
appendage morphogenesisGO:00351071490.018
multicellular organismal signalingGO:0035637910.018
cellular macromolecule catabolic processGO:00442652060.018
Mouse
proteoglycan biosynthetic processGO:0030166200.018
canonical wnt signaling pathwayGO:00600701300.018
cytokine mediated signaling pathwayGO:00192211150.018
regulation of cytoskeleton organizationGO:00514931220.018
regulation of response to drugGO:200102320.018
skeletal muscle fiber developmentGO:0048741580.018
apoptotic signaling pathwayGO:00971903060.018
Mouse
respiratory system developmentGO:00605411900.018
locomotory behaviorGO:00076261950.018
nephron tubule morphogenesisGO:0072078680.018
establishment of synaptic vesicle localizationGO:0097480570.018
regulation of cellular amino acid metabolic processGO:000652150.018
epithelial tube morphogenesisGO:00605623030.018
embryonic skeletal system developmentGO:00487061200.018
covalent chromatin modificationGO:00165691630.018
actin filament organizationGO:00070151130.018
anatomical structure homeostasisGO:00602491450.018
negative regulation of protein transportGO:0051224460.018
response to organonitrogen compoundGO:00102432460.018
urogenital system developmentGO:00016552610.018
tube formationGO:00351481400.018
regulation of nucleoside metabolic processGO:00091181300.017
modification dependent protein catabolic processGO:00199411330.017
Mouse
cognitionGO:00508901490.017
regulation of asymmetric cell divisionGO:000978640.017
golgi vesicle transportGO:0048193300.017
regulation of ossificationGO:00302781120.017
Mouse
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.017
response to radiationGO:00093141650.017
regulation of gtp catabolic processGO:00331241130.017
morphogenesis of a branching structureGO:00017632030.017
regulation of cell projection organizationGO:00313442060.017
positive regulation of purine nucleotide metabolic processGO:19005441140.017
engulfment of apoptotic cellGO:004365230.017
negative regulation of protein metabolic processGO:00512482820.017
ribonucleoside metabolic processGO:00091192450.017
cellular protein complex disassemblyGO:0043624360.017
formation of primary germ layerGO:0001704770.017
amide transportGO:00428861380.017
cell divisionGO:00513011200.017
positive regulation of protein kinase activityGO:00458601440.017
renal system developmentGO:00720012250.016
learning or memoryGO:00076111480.016
amine metabolic processGO:0009308450.016
digestive system developmentGO:00551232000.016
response to endoplasmic reticulum stressGO:0034976530.016
neural tube developmentGO:00219151600.016
positive regulation of gtp catabolic processGO:0033126850.016
regulation of actin cytoskeleton organizationGO:0032956840.016
divalent metal ion transportGO:00708381720.016
regulation of cellular protein catabolic processGO:1903362610.016
Mouse
connective tissue developmentGO:00614481790.016
posttranscriptional regulation of gene expressionGO:00106081550.016
cellular response to salt stressGO:007147210.016
actin filament polymerizationGO:0030041440.016
ubiquitin dependent protein catabolic processGO:00065111290.016
Mouse
cellular chemical homeostasisGO:00550822150.016
negative regulation of molecular functionGO:00440922580.016
Mouse
compound eye developmentGO:004874910.016
Fly
activation of meiosis involved in egg activationGO:006046620.016
telencephalon developmentGO:00215371860.016
negative regulation of cell fate specificationGO:000999640.015
peptidyl serine phosphorylationGO:0018105740.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
Mouse
aminoglycan metabolic processGO:0006022340.015
protein methylationGO:0006479810.015
muscle fiber developmentGO:0048747760.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
cation homeostasisGO:00550802120.015
hormone secretionGO:00468791280.015
muscle cell differentiationGO:00426922610.015
response to peptideGO:19016521360.015
regulation of protein import into nucleusGO:0042306520.015
myeloid leukocyte differentiationGO:00025731190.015
cell maturationGO:00484691270.015
mitotic cell cycle processGO:19030471590.015
Fly
retina development in camera type eyeGO:00600411190.015
cellular component assembly involved in morphogenesisGO:00109271390.015
cellular response to acidic phGO:007146840.015
cellular divalent inorganic cation homeostasisGO:00725031270.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
ascending thin limb developmentGO:007202120.015
renal tubule developmentGO:0061326870.015
negative regulation of intracellular protein transportGO:0090317270.015
peptide secretionGO:00027901140.015
negative regulation of growthGO:0045926990.015
carbohydrate homeostasisGO:00335001280.015
neuron deathGO:00709971540.014
immune response regulating signaling pathwayGO:00027641250.014
positive regulation of cytokine productionGO:00018191740.014
metal ion homeostasisGO:00550651890.014
regulation of innate immune responseGO:0045088910.014
Fly
muscle cell developmentGO:00550011330.014
organelle localizationGO:00516401790.014
muscle contractionGO:00069361010.014
inorganic cation transmembrane transportGO:00986622070.014
Rat
innate immune responseGO:00450871570.014
Fly
mechanosensory behaviorGO:000763860.014
internal protein amino acid acetylationGO:0006475420.014
regulation of mitotic cell cycle phase transitionGO:1901990730.014
Fly
regulation of cell activationGO:00508652890.014
regulation of ras gtpase activityGO:0032318880.014
regulation of protein processingGO:0070613960.014
regulation of lymphocyte activationGO:00512492400.014
positive regulation of cell motilityGO:20001471160.014
regulation of nucleocytoplasmic transportGO:0046822730.014
positive regulation of nucleotide metabolic processGO:00459811140.014
regulation of anatomical structure sizeGO:00900661780.014
cellular homeostasisGO:00197252400.014
synapse organizationGO:00508081250.014
protein alkylationGO:0008213810.014
organic hydroxy compound metabolic processGO:19016152030.013
stem cell developmentGO:00488642190.013
regulation of t cell activationGO:00508631700.013
internal peptidyl lysine acetylationGO:0018393420.013
peptide transportGO:00158331330.013
glial cell apoptotic processGO:003434930.013
regulation of ras protein signal transductionGO:00465781140.013
positive regulation of bindingGO:0051099490.013
nephron developmentGO:00720061090.013
photoreceptor cell differentiationGO:0046530520.013
multi organism reproductive behaviorGO:0044705290.013
multicellular organismal reproductive behaviorGO:0033057230.013
tissue migrationGO:0090130680.013
negative regulation of cytoplasmic transportGO:1903650290.013
anion transportGO:00068201770.013
skeletal muscle organ developmentGO:00605381630.013
forebrain developmentGO:00309003020.013
germ cell developmentGO:00072811850.013
camera type eye developmentGO:00430102660.013
cellular response to hormone stimulusGO:00328701500.013
limb morphogenesisGO:00351081490.013
morphogenesis of a branching epitheliumGO:00611381930.013
actin filament bundle assemblyGO:0051017400.012
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic processGO:001501410.012
leukocyte migrationGO:00509001240.012
reproductive behaviorGO:0019098320.012
spermatid developmentGO:00072861080.012
retina morphogenesis in camera type eyeGO:0060042450.012
cell type specific apoptotic processGO:00972852680.012
Mouse
organophosphate biosynthetic processGO:00904071220.012
protein ubiquitinationGO:00165671710.012
aminoglycan biosynthetic processGO:0006023150.012
hindbrain developmentGO:00309021280.012
circulatory system processGO:00030131970.012
regulation of translationGO:0006417710.012
sequestering of metal ionGO:0051238190.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
asymmetric neuroblast divisionGO:005505910.012
regulation of canonical wnt signaling pathwayGO:0060828820.012
nephron morphogenesisGO:0072028690.012
response to granulocyte macrophage colony stimulating factorGO:009701230.012
regulation of autophagyGO:0010506300.012
toxin transportGO:1901998380.012
regulation of lymphocyte differentiationGO:00456191070.012
protein kinase b signalingGO:0043491740.012
activation of mapk activityGO:0000187590.012
spleen developmentGO:0048536390.012
mitotic cell cycleGO:00002781950.012
Fly
cellularizationGO:000734910.012
nephron epithelium developmentGO:0072009920.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
positive regulation of cell cycleGO:0045787920.012
positive regulation of tor signalingGO:003200830.012
cyclic nucleotide metabolic processGO:0009187590.012
regulation of homeostatic processGO:00328441820.012
smoothened signaling pathwayGO:00072241050.012
regulation of mapk cascadeGO:00434082480.011
morphogenesis of embryonic epitheliumGO:00163311590.011
nephron epithelium morphogenesisGO:0072088680.011
ear developmentGO:00435832000.011
limb developmentGO:00601731660.011
mammary gland epithelium developmentGO:0061180650.011
regulation of neuron deathGO:19012141340.011
negative regulation of protein localization to nucleusGO:1900181230.011
synaptic vesicle transportGO:0048489570.011
muscle system processGO:00030121410.011
sensory organ morphogenesisGO:00905962420.011
regulation of epithelial cell proliferationGO:00506781410.011
regulation of protein sumoylationGO:003323340.011
Human
negative regulation of cation channel activityGO:200125810.011
positive regulation of cellular component biogenesisGO:0044089940.011
single fertilizationGO:0007338820.011
glycosaminoglycan biosynthetic processGO:0006024150.011
adult locomotory behaviorGO:0008344910.011
negative regulation of stress fiber assemblyGO:005149740.011
myotube differentiationGO:00149021050.011
appendage developmentGO:00487361660.011
circadian regulation of gene expressionGO:0032922480.011
endocytosisGO:00068971680.011
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.011
reactive oxygen species metabolic processGO:0072593840.011
regenerationGO:0031099380.011
regulation of defense responseGO:00313472330.011
Fly
negative regulation of cell proliferationGO:00082852960.011
cell fate specificationGO:0001708720.011
peptide hormone secretionGO:00300721090.011
response to fibroblast growth factorGO:0071774470.010
protein depolymerizationGO:0051261340.010
actin filament based movementGO:0030048230.010
cell growthGO:00160491300.010
regulation of secretionGO:00510462740.010
positive regulation of protein transportGO:0051222930.010
regulation of cell motilityGO:20001452360.010
cellular metal ion homeostasisGO:00068751510.010
i kappab kinase nf kappab signalingGO:0007249850.010
glial cell differentiationGO:00100011310.010
liver developmentGO:0001889660.010
proteoglycan metabolic processGO:0006029380.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
adult behaviorGO:00305341350.010
insulin secretionGO:0030073890.010
exocytosisGO:00068871210.010
mesonephros developmentGO:0001823970.010
microtubule cytoskeleton organizationGO:00002261570.010
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.010
digestive tract developmentGO:00485651900.010
plasma membrane organizationGO:0007009900.010
positive regulation of cell migrationGO:00303351090.010
hepaticobiliary system developmentGO:0061008670.010
regulation of actin filament based processGO:0032970990.010

Pias3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.015
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
disease of anatomical entityDOID:700.012