Mus musculus

42 known processes

Tk2

thymidine kinase 2, mitochondrial

(Aliases: AU024611)

Tk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecule catabolic processGO:00090572810.114
regulation of cellular amino acid metabolic processGO:000652150.107
dna metabolic processGO:00062593030.102
cellular amine metabolic processGO:0044106440.099
oxidation reduction processGO:00551143420.095
cellular macromolecule catabolic processGO:00442652060.091
regulation of cellular amine metabolic processGO:0033238200.084
intra golgi vesicle mediated transportGO:000689110.062
protein ubiquitinationGO:00165671710.062
cellular amino acid metabolic processGO:00065201030.058
regulation of cellular ketone metabolic processGO:0010565660.057
dephosphorylationGO:00163111290.054
mitotic cell cycleGO:00002781950.051
cation transportGO:00068123990.048
negative regulation of cellular amino acid metabolic processGO:004576300.048
endomembrane system organizationGO:00102561470.045
cellular response to dna damage stimulusGO:00069742070.044
protein modification by small protein conjugation or removalGO:00706472070.043
membrane organizationGO:00610242450.043
response to light stimulusGO:00094161350.043
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.043
cytoplasmic transportGO:00164822340.042
modification dependent protein catabolic processGO:00199411330.041
proteolysis involved in cellular protein catabolic processGO:00516031470.041
mitotic cell cycle processGO:19030471590.040
organelle fissionGO:00482851700.040
retrograde transport endosome to golgiGO:004214720.039
regulation of cell cycleGO:00517262810.038
modification dependent macromolecule catabolic processGO:00436321330.038
nuclear divisionGO:00002801580.037
cellular ketone metabolic processGO:0042180840.037
nucleotide metabolic processGO:00091173320.035
negative regulation of cellular amine metabolic processGO:003323910.035
proteasomal protein catabolic processGO:0010498980.035
amine metabolic processGO:0009308450.035
purine nucleotide metabolic processGO:00061633020.034
ubiquitin dependent protein catabolic processGO:00065111290.034
purine ribonucleotide metabolic processGO:00091502900.033
ribonucleoside metabolic processGO:00091192450.033
negative regulation of cellular protein metabolic processGO:00322692470.033
positive regulation of cellular amino acid metabolic processGO:004576430.032
nucleoside phosphate metabolic processGO:00067533380.032
synaptic transmissionGO:00072683290.030
cellular response to cytokine stimulusGO:00713451890.030
regulation of vesicle mediated transportGO:00606271390.030
positive regulation of cellular amine metabolic processGO:003324050.029
nucleobase containing small molecule metabolic processGO:00550863520.029
regulation of system processGO:00440572000.029
carbohydrate derivative biosynthetic processGO:19011371830.028
negative regulation of cell cycleGO:00457861230.028
hexose metabolic processGO:0019318980.028
cellular carbohydrate metabolic processGO:00442621190.028
cation transmembrane transportGO:00986552660.027
response to radiationGO:00093141650.026
skeletal system developmentGO:00015013560.026
cellular protein catabolic processGO:00442571550.025
purine containing compound catabolic processGO:00725232130.024
carbohydrate derivative catabolic processGO:19011362310.024
regulation of protein transportGO:00512231630.024
negative regulation of cellular component organizationGO:00511291940.024
glycosyl compound metabolic processGO:19016572460.024
phospholipid metabolic processGO:0006644870.024
purine nucleoside triphosphate metabolic processGO:00091442260.024
dna repairGO:00062811070.023
digestive tract developmentGO:00485651900.023
inorganic cation transmembrane transportGO:00986622070.023
female meiosis chromosome segregationGO:001632110.023
protein modification by small protein conjugationGO:00324461870.023
ribonucleotide metabolic processGO:00092592910.023
cellular nitrogen compound catabolic processGO:00442702800.022
response to growth factorGO:00708481980.022
establishment of protein localization to membraneGO:0090150540.022
purine containing compound metabolic processGO:00725213110.022
vesicle localizationGO:0051648860.022
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
cellular response to extracellular stimulusGO:0031668810.022
protein localization to organelleGO:00333651850.022
nucleoside phosphate catabolic processGO:19012922220.022
nucleoside triphosphate metabolic processGO:00091412300.022
striated muscle tissue developmentGO:00147062930.022
positive regulation of protein phosphorylationGO:00019342420.021
regulation of protein localizationGO:00328802310.021
regulation of protein kinase activityGO:00458592320.021
small molecule catabolic processGO:0044282710.021
nitrogen compound transportGO:00717052710.020
regulation of mitotic cell cycleGO:00073461260.020
membrane fusionGO:0061025380.020
negative regulation of phosphate metabolic processGO:00459361840.020
macroautophagyGO:0016236210.020
digestive system developmentGO:00551232000.020
digestive tract morphogenesisGO:00485461470.020
purine nucleoside metabolic processGO:00422782410.020
posttranscriptional regulation of gene expressionGO:00106081550.020
endocytosisGO:00068971680.020
meiotic cell cycleGO:00513211220.020
male gamete generationGO:00482322850.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
organelle assemblyGO:00709251770.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
viral gene expressionGO:001908030.019
ion transmembrane transportGO:00342203610.019
regulation of synaptic growth at neuromuscular junctionGO:000858240.019
negative regulation of molecular functionGO:00440922580.019
regulation of homeostatic processGO:00328441820.019
positive regulation of dna templated transcription elongationGO:003278620.018
mapk cascadeGO:00001652810.018
organic hydroxy compound metabolic processGO:19016152030.018
nucleoside catabolic processGO:00091642060.018
protein importGO:00170381010.018
protein catabolic processGO:00301632210.018
organonitrogen compound biosynthetic processGO:19015661920.018
nucleoside triphosphate catabolic processGO:00091432050.018
anatomical structure homeostasisGO:00602491450.018
spermatogenesisGO:00072832840.018
protein targetingGO:00066051430.018
positive regulation of protein modification processGO:00314012990.018
lipid modificationGO:0030258650.017
regulation of clathrin mediated endocytosisGO:200036940.017
intracellular protein transportGO:00068862040.017
response to organic cyclic compoundGO:00140701980.017
cellular response to growth factor stimulusGO:00713631970.017
regulation of organelle organizationGO:00330432890.017
divalent metal ion transportGO:00708381720.017
locomotory behaviorGO:00076261950.017
divalent inorganic cation transportGO:00725111780.017
heterocycle catabolic processGO:00467002800.017
histone modificationGO:00165701590.017
regulation of kinase activityGO:00435492490.017
golgi to endosome transportGO:000689530.017
monosaccharide metabolic processGO:00059961060.017
response to epidermal growth factorGO:007084940.016
muscle tissue developmentGO:00605373080.016
regulation of hydrolase activityGO:00513362460.016
response to oxidative stressGO:00069791230.016
peptidyl tyrosine phosphorylationGO:00181081430.016
transmembrane transportGO:00550854120.016
purine ribonucleoside metabolic processGO:00461282410.016
ribonucleoside catabolic processGO:00424542060.016
regulation of membrane potentialGO:00423911920.016
carbohydrate metabolic processGO:00059752300.016
peptidyl serine phosphorylationGO:0018105740.016
cellular lipid metabolic processGO:00442553230.015
regulation of intracellular transportGO:00323861590.015
negative regulation of protein metabolic processGO:00512482820.015
regulation of transcription from rna polymerase iii promoterGO:000635920.015
glycerolipid metabolic processGO:00464861220.015
carbohydrate biosynthetic processGO:0016051740.015
interspecies interaction between organismsGO:0044419830.015
apoptotic signaling pathwayGO:00971903060.015
g protein coupled receptor signaling pathwayGO:00071862430.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of endocytosisGO:0030100690.015
negative regulation of organelle organizationGO:0010639900.015
nucleocytoplasmic transportGO:00069131390.014
cellular response to external stimulusGO:0071496880.014
regulation of transferase activityGO:00513382630.014
protein maturationGO:00516041760.014
regulation of ion transportGO:00432692150.014
positive regulation of transferase activityGO:00513471670.014
vesicle organizationGO:0016050600.014
skeletal muscle organ developmentGO:00605381630.014
regulation of neuron deathGO:19012141340.014
polysaccharide metabolic processGO:0005976390.014
ribonucleotide catabolic processGO:00092612080.014
regulation of cellular component biogenesisGO:00440871810.014
chromosome segregationGO:0007059480.014
nucleoside metabolic processGO:00091162460.014
neuron deathGO:00709971540.014
cellular pigmentationGO:0033059200.014
organophosphate catabolic processGO:00464342320.014
mitotic nuclear divisionGO:0007067480.014
response to uvGO:0009411440.013
cytokine productionGO:00018163190.013
response to nutrient levelsGO:00316671090.013
organophosphate biosynthetic processGO:00904071220.013
positive regulation of nucleotide metabolic processGO:00459811140.013
regulation of protein maturationGO:1903317960.013
alcohol metabolic processGO:00060661160.013
organonitrogen compound catabolic processGO:19015652640.013
regulation of mapk cascadeGO:00434082480.013
muscle cell differentiationGO:00426922610.013
cellular polysaccharide metabolic processGO:0044264380.013
regulation of secretionGO:00510462740.013
negative regulation of glycogen biosynthetic processGO:004571910.013
regulation of intracellular protein transportGO:0033157820.013
smoothened signaling pathwayGO:00072241050.013
regulation of interleukin 8 productionGO:003267730.013
peptidyl threonine modificationGO:0018210310.013
nucleotide catabolic processGO:00091662170.013
regulation of cell cycle phase transitionGO:1901987770.013
sensory perceptionGO:00076002450.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
regulation of epithelial cell proliferationGO:00506781410.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
regulation of chromosome organizationGO:0033044830.013
renal system developmentGO:00720012250.013
inositol phosphate catabolic processGO:007154540.013
regulation of neuron apoptotic processGO:00435231220.013
gtp catabolic processGO:00061841430.013
organelle fusionGO:0048284280.012
cell type specific apoptotic processGO:00972852680.012
negative regulation of phosphorus metabolic processGO:00105631840.012
epithelial cell proliferationGO:00506731740.012
intra s dna damage checkpointGO:003157340.012
interleukin 8 productionGO:003263740.012
regulation of purine nucleotide metabolic processGO:19005421690.012
asymmetric neuroblast divisionGO:005505910.012
proteoglycan biosynthetic processGO:0030166200.012
negative regulation of viral transcriptionGO:003289730.012
regulation of cell migrationGO:00303342190.012
fibroblast growth factor receptor signaling pathwayGO:0008543460.012
glycerophospholipid metabolic processGO:0006650710.012
peptidyl amino acid modificationGO:00181933360.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
organic cyclic compound catabolic processGO:19013612950.012
phosphorylated carbohydrate dephosphorylationGO:004683840.012
sperm motilityGO:0030317470.012
protein import into nucleusGO:0006606950.012
plasma membrane organizationGO:0007009900.012
regulation of body fluid levelsGO:00508781620.012
reactive nitrogen species metabolic processGO:200105700.012
regulation of cytoplasmic transportGO:19036491120.012
dna recombinationGO:0006310920.012
sulfur compound metabolic processGO:00067901000.012
regulation of lymphocyte activationGO:00512492400.012
rna processingGO:00063961050.012
regulation of ossificationGO:00302781120.012
protein localization to membraneGO:00726571080.011
regulation of cell cycle processGO:00105641600.011
multicellular organismal signalingGO:0035637910.011
cellular protein complex assemblyGO:00436231160.011
positive regulation of intracellular transportGO:0032388700.011
golgi vesicle transportGO:0048193300.011
positive regulation of programmed cell deathGO:00430682180.011
positive regulation of protein kinase activityGO:00458601440.011
regulation of cell projection organizationGO:00313442060.011
negative regulation of neuron deathGO:1901215980.011
rna splicingGO:0008380540.011
homeostasis of number of cellsGO:00488722100.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.011
adult behaviorGO:00305341350.011
purine ribonucleoside catabolic processGO:00461302050.011
ras protein signal transductionGO:0007265770.011
myosin filament organizationGO:003103330.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
meiotic nuclear divisionGO:00071261150.011
sequestering of metal ionGO:0051238190.011
regulation of protein processingGO:0070613960.011
regulation of leukocyte differentiationGO:19021051590.011
purine nucleotide catabolic processGO:00061952110.011
response to extracellular stimulusGO:00099911270.011
positive regulation of apoptotic cell clearanceGO:200042730.011
central nervous system neuron differentiationGO:00219531620.011
regulation of establishment of protein localizationGO:00702011810.011
nucleoside phosphate biosynthetic processGO:1901293790.011
regulation of feeding behaviorGO:006025930.011
regulation of lymphocyte mediated immunityGO:0002706840.011
adult locomotory behaviorGO:0008344910.011
purine ribonucleotide catabolic processGO:00091542080.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
protein localization to nucleusGO:00345041210.011
actin cytoskeleton organizationGO:00300362200.011
establishment of protein localization to organelleGO:00725941180.010
negative regulation of protein modification processGO:00314001630.010
regulation of neuron differentiationGO:00456642810.010
lymphocyte mediated immunityGO:00024491390.010
skin developmentGO:00435882200.010
cell adhesionGO:00071553290.010
negative regulation of transferase activityGO:0051348850.010
viral processGO:0016032410.010
regulation of secretion by cellGO:19035302490.010
negative regulation of cell proliferationGO:00082852960.010
peptidyl serine modificationGO:0018209830.010
chemotaxisGO:00069352470.010
regulation of cell activationGO:00508652890.010
immune effector processGO:00022523210.010
hematopoietic progenitor cell differentiationGO:00022441430.010
peptidyl tyrosine modificationGO:00182121450.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
regulation of neuron projection developmentGO:00109751690.010
regulation of osteoblast differentiationGO:0045667670.010
positive regulation of hydrolase activityGO:00513451480.010
regulation of leukocyte mediated immunityGO:00027031040.010
membrane lipid metabolic processGO:0006643530.010

Tk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.055
nervous system diseaseDOID:86300.055
disease of anatomical entityDOID:700.055
disease of metabolismDOID:001466700.049
inherited metabolic disorderDOID:65500.049
lysosomal storage diseaseDOID:321100.013
lipid storage diseaseDOID:945500.013
sphingolipidosisDOID:192700.013
cardiovascular system diseaseDOID:128700.011