Mus musculus

39 known processes

Tk1

thymidine kinase 1

(Aliases: Tk1a,Tk1b,Tk-1,D530002A18Rik)

Tk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.491
cellular response to dna damage stimulusGO:00069742070.415
dna replicationGO:0006260520.290
nucleobase containing small molecule metabolic processGO:00550863520.236
aromatic compound catabolic processGO:00194392860.231
chromosome segregationGO:0007059480.202
purine nucleoside triphosphate metabolic processGO:00091442260.185
deoxyribonucleotide metabolic processGO:0009262140.169
purine ribonucleotide metabolic processGO:00091502900.161
heterocycle catabolic processGO:00467002800.150
nucleotide metabolic processGO:00091173320.148
nucleoside phosphate metabolic processGO:00067533380.143
purine ribonucleoside triphosphate metabolic processGO:00092052200.128
cellular nitrogen compound catabolic processGO:00442702800.123
ribonucleoside metabolic processGO:00091192450.121
purine ribonucleoside metabolic processGO:00461282410.117
purine containing compound metabolic processGO:00725213110.113
regulation of cell cycleGO:00517262810.112
protein ubiquitinationGO:00165671710.112
dna repairGO:00062811070.109
organic cyclic compound catabolic processGO:19013612950.107
organelle localizationGO:00516401790.102
nucleoside triphosphate metabolic processGO:00091412300.101
mitotic sister chromatid segregationGO:0000070140.096
translesion synthesisGO:001998510.095
nucleoside monophosphate metabolic processGO:0009123850.093
purine nucleoside metabolic processGO:00422782410.089
proteasomal protein catabolic processGO:0010498980.089
dna endoreduplicationGO:004202340.089
covalent chromatin modificationGO:00165691630.087
organonitrogen compound catabolic processGO:19015652640.086
lateral inhibitionGO:004633110.083
asymmetric stem cell divisionGO:009872230.082
protein processingGO:00164851630.082
cellular protein catabolic processGO:00442571550.080
cellular amino acid metabolic processGO:00065201030.078
histone modificationGO:00165701590.076
purine nucleotide metabolic processGO:00061633020.076
nucleoside catabolic processGO:00091642060.074
nuclear dna replicationGO:003326030.073
purine containing compound catabolic processGO:00725232130.073
dna dependent dna replicationGO:0006261240.070
macromolecule catabolic processGO:00090572810.070
ubiquitin dependent protein catabolic processGO:00065111290.069
protein modification by small protein conjugation or removalGO:00706472070.067
ribonucleoside triphosphate catabolic processGO:00092031990.067
ribonucleotide metabolic processGO:00092592910.066
meiotic cell cycle processGO:1903046770.066
modification dependent protein catabolic processGO:00199411330.065
cellular homeostasisGO:00197252400.065
ribonucleoside triphosphate metabolic processGO:00091992200.064
nucleoside metabolic processGO:00091162460.064
purine ribonucleoside catabolic processGO:00461302050.063
purine nucleotide catabolic processGO:00061952110.061
regulation of cellular ketone metabolic processGO:0010565660.060
proteolysis involved in cellular protein catabolic processGO:00516031470.059
mitotic cell cycleGO:00002781950.059
modification dependent macromolecule catabolic processGO:00436321330.059
amine metabolic processGO:0009308450.059
mitotic chromosome condensationGO:000707610.058
nucleoside phosphate catabolic processGO:19012922220.058
deoxyribonucleotide biosynthetic processGO:000926360.057
cleavage furrow formationGO:003608920.057
meiotic nuclear divisionGO:00071261150.056
ribose phosphate metabolic processGO:00196932910.055
response to oxidative stressGO:00069791230.055
cellular ketone metabolic processGO:0042180840.054
regulation of cellular amino acid metabolic processGO:000652150.052
ribonucleoside monophosphate metabolic processGO:0009161800.051
peptidyl amino acid modificationGO:00181933360.051
organelle assemblyGO:00709251770.050
nucleoside phosphate biosynthetic processGO:1901293790.049
carbohydrate derivative biosynthetic processGO:19011371830.048
regulation of cellular amine metabolic processGO:0033238200.047
dna recombinationGO:0006310920.046
chromatin modificationGO:00165681870.046
endocytosisGO:00068971680.046
germ cell developmentGO:00072811850.046
purine nucleoside catabolic processGO:00061522050.045
oxidation reduction processGO:00551143420.045
regulation of secretionGO:00510462740.045
regulation of mitotic cell cycle phase transitionGO:1901990730.045
positive regulation of cellular amino acid metabolic processGO:004576430.044
cellular lipid metabolic processGO:00442553230.044
negative regulation of chromatin silencingGO:003193610.043
organophosphate catabolic processGO:00464342320.042
cellular amine metabolic processGO:0044106440.042
male gamete generationGO:00482322850.041
protein oligomerizationGO:0051259670.041
Human
microtubule based processGO:00070172360.040
regulation of cellular response to stressGO:00801351590.040
regulation of organelle organizationGO:00330432890.039
nucleoside triphosphate catabolic processGO:00091432050.039
regulation of hydrolase activityGO:00513362460.039
regulation of dna replicationGO:0006275170.039
carbohydrate derivative catabolic processGO:19011362310.039
regulation of cell cycle processGO:00105641600.038
regulation of cellular catabolic processGO:00313292420.038
spindle midzone assemblyGO:005125510.038
development of primary sexual characteristicsGO:00451371430.037
double strand break repairGO:0006302480.037
regulation of cellular protein catabolic processGO:1903362610.036
meiosis iGO:0007127600.036
cation transportGO:00068123990.036
sister chromatid cohesionGO:0007062120.036
sister chromatid segregationGO:0000819200.035
synapsisGO:0007129340.035
nucleotide catabolic processGO:00091662170.034
purine nucleoside monophosphate catabolic processGO:0009128580.034
ribonucleoside catabolic processGO:00424542060.034
regulation of dna dependent dna replication initiationGO:003017430.034
positive regulation of cellular amine metabolic processGO:003324050.033
circulatory system processGO:00030131970.033
organonitrogen compound biosynthetic processGO:19015661920.033
nuclear divisionGO:00002801580.033
cellular protein complex assemblyGO:00436231160.033
mitotic nuclear divisionGO:0007067480.033
synaptonemal complex assemblyGO:0007130130.032
positive regulation of chromosome segregationGO:005198440.032
response to organonitrogen compoundGO:00102432460.031
glycosyl compound metabolic processGO:19016572460.031
apoptotic signaling pathwayGO:00971903060.031
protein catabolic processGO:00301632210.031
gene silencingGO:0016458380.031
purine ribonucleoside monophosphate catabolic processGO:0009169570.031
negative regulation of phosphorus metabolic processGO:00105631840.030
cyclin catabolic processGO:000805410.030
regulation of mitotic cell cycleGO:00073461260.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.030
mitotic cytokinesisGO:000028140.029
mitotic cell cycle processGO:19030471590.029
regulation of chromosome segregationGO:0051983210.028
positive regulation of mitotic sister chromatid separationGO:190197020.028
ribonucleotide catabolic processGO:00092612080.028
mitotic sister chromatid cohesionGO:000706410.028
nucleoside monophosphate catabolic processGO:0009125590.028
atp metabolic processGO:0046034750.028
regulation of defense responseGO:00313472330.028
positive regulation of cellular catabolic processGO:00313311480.028
positive regulation of protein phosphorylationGO:00019342420.027
protein localization to organelleGO:00333651850.027
peptidyl serine phosphorylationGO:0018105740.027
purine nucleoside triphosphate catabolic processGO:00091462030.026
chromatin organizationGO:00063252060.026
cell type specific apoptotic processGO:00972852680.026
gonad developmentGO:00084061410.026
regulation of transferase activityGO:00513382630.025
anion transportGO:00068201770.025
female gamete generationGO:0007292740.025
blood circulationGO:00080151950.025
response to iron ionGO:001003940.025
protein maturationGO:00516041760.025
regulation of spindle organizationGO:009022420.025
spindle assembly involved in mitosisGO:009030740.025
microtubule based movementGO:0007018840.024
purine ribonucleoside monophosphate metabolic processGO:0009167800.024
dephosphorylationGO:00163111290.024
mapk cascadeGO:00001652810.024
spermatogenesisGO:00072832840.024
cytokine productionGO:00018163190.024
genitalia developmentGO:0048806370.023
guanosine containing compound metabolic processGO:19010681440.023
regulation of proteolysisGO:00301621640.023
cellular chemical homeostasisGO:00550822150.023
dna unwinding involved in dna replicationGO:000626850.023
glycosyl compound catabolic processGO:19016582060.023
gland developmentGO:00487323300.023
leukocyte homeostasisGO:0001776790.022
negative regulation of cell proliferationGO:00082852960.022
lymphocyte differentiationGO:00300982420.022
purine deoxyribonucleoside triphosphate metabolic processGO:000921570.022
histone serine phosphorylationGO:003540450.022
regulation of mitotic spindle organizationGO:006023620.021
sensory perceptionGO:00076002450.021
gtp metabolic processGO:00460391440.021
regulation of mapk cascadeGO:00434082480.021
mitochondrion organizationGO:00070051340.021
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.021
myosin filament assemblyGO:003103420.020
single fertilizationGO:0007338820.020
synaptic transmissionGO:00072683290.020
response to organic cyclic compoundGO:00140701980.020
microtubule cytoskeleton organizationGO:00002261570.020
energy derivation by oxidation of organic compoundsGO:0015980770.020
positive regulation of protein modification processGO:00314012990.020
spindle assembly involved in female meiosisGO:000705630.020
protein polymerizationGO:0051258570.020
cytokinetic processGO:003250620.020
cellular response to biotic stimulusGO:0071216920.019
ion transmembrane transportGO:00342203610.019
positive regulation of protein kinase activityGO:00458601440.019
cofactor metabolic processGO:0051186800.019
protein tetramerizationGO:0051262230.019
Human
regulation of response to woundingGO:19030341890.019
regulation of dna dependent dna replicationGO:009032980.019
positive regulation of exit from mitosisGO:003153610.019
neural tube developmentGO:00219151600.019
regulation of inflammatory responseGO:00507271470.019
establishment of organelle localizationGO:00516561220.018
cell cycle g1 s phase transitionGO:0044843570.018
organelle fissionGO:00482851700.018
mitotic sister chromatid separationGO:005130690.018
negative regulation of protein modification processGO:00314001630.018
cellular amino acid catabolic processGO:0009063250.018
carbohydrate metabolic processGO:00059752300.018
negative regulation of cellular component organizationGO:00511291940.018
spindle assembly involved in meiosisGO:009030640.018
nitrogen compound transportGO:00717052710.018
nucleotide biosynthetic processGO:0009165780.018
regulation of transcription by chromatin organizationGO:003440100.018
muscle cell developmentGO:00550011330.018
regulation of protein serine threonine kinase activityGO:00719001570.018
transmembrane transportGO:00550854120.018
negative regulation of phosphate metabolic processGO:00459361840.018
cytoplasmic transportGO:00164822340.018
regulation of exit from mitosisGO:000709610.018
female meiotic divisionGO:0007143210.017
leukocyte differentiationGO:00025213420.017
regulation of cell motilityGO:20001452360.017
myeloid cell differentiationGO:00300992330.017
fibroblast proliferationGO:0048144350.017
microtubule cytoskeleton organization involved in mitosisGO:190285040.017
negative regulation of gene silencingGO:006096920.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
regulation of lymphocyte activationGO:00512492400.017
fertilizationGO:00095661270.017
regulation of cell cycle phase transitionGO:1901987770.017
response to lipopolysaccharideGO:00324961280.017
cell adhesionGO:00071553290.017
synaptonemal complex organizationGO:0070193150.017
response to inorganic substanceGO:0010035960.017
positive regulation of hydrolase activityGO:00513451480.017
posttranscriptional regulation of gene expressionGO:00106081550.017
negative regulation of molecular functionGO:00440922580.017
embryonic epithelial tube formationGO:00018381300.017
protein heterotetramerizationGO:005129040.017
cytokinesisGO:0000910170.017
organophosphate biosynthetic processGO:00904071220.017
positive regulation of programmed cell deathGO:00430682180.017
positive regulation of cell cycleGO:0045787920.016
hepaticobiliary system developmentGO:0061008670.016
meiotic cell cycleGO:00513211220.016
regulation of apoptotic signaling pathwayGO:20012331970.016
ras protein signal transductionGO:0007265770.016
regulation of secretion by cellGO:19035302490.016
striated muscle myosin thick filament assemblyGO:007168810.016
blood vessel morphogenesisGO:00485142850.016
regulation of cell migrationGO:00303342190.016
peptidyl serine modificationGO:0018209830.016
inflammatory responseGO:00069542440.016
purine ribonucleotide catabolic processGO:00091542080.016
cellular metal ion homeostasisGO:00068751510.016
positive regulation of proteolysisGO:0045862850.016
regulation of cell projection organizationGO:00313442060.016
asymmetric neuroblast divisionGO:005505910.015
cellular response to lipidGO:00713961450.015
regulation of cell divisionGO:0051302760.015
muscle cell differentiationGO:00426922610.015
dna integrity checkpointGO:0031570280.015
carbohydrate homeostasisGO:00335001280.015
response to metal ionGO:0010038470.015
response to acid chemicalGO:00011011110.015
epithelial tube morphogenesisGO:00605623030.015
cellular component assembly involved in morphogenesisGO:00109271390.015
regulation of cytokine productionGO:00018172660.015
regulation of kinase activityGO:00435492490.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.015
cellular response to hormone stimulusGO:00328701500.015
regulation of mitotic sister chromatid segregationGO:0033047120.015
camera type eye developmentGO:00430102660.014
rho protein signal transductionGO:0007266320.014
t cell activationGO:00421102890.014
cell maturationGO:00484691270.014
heart contractionGO:0060047930.014
response to oxygen levelsGO:0070482620.014
atp catabolic processGO:0006200550.014
negative regulation of phosphorylationGO:00423261660.014
membrane organizationGO:00610242450.014
positive regulation of mitotic metaphase anaphase transitionGO:004584220.014
peptide transportGO:00158331330.014
protein kinase b signalingGO:0043491740.014
regulation of nucleoside metabolic processGO:00091181300.014
negative regulation of cell cycleGO:00457861230.014
cell divisionGO:00513011200.014
myosin filament organizationGO:003103330.014
neuron apoptotic processGO:00514021420.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
positive regulation of apoptotic processGO:00430652170.014
homeostasis of number of cellsGO:00488722100.014
regulation of establishment of protein localizationGO:00702011810.014
positive regulation of nervous system developmentGO:00519622210.014
regulation of metaphase anaphase transition of cell cycleGO:190209990.014
positive regulation of protein transportGO:0051222930.014
small gtpase mediated signal transductionGO:0007264970.014
cellular response to growth factor stimulusGO:00713631970.014
glucose homeostasisGO:00425931280.014
developmental maturationGO:00217001930.014
cellular ion homeostasisGO:00068731650.013
cofactor biosynthetic processGO:0051188410.013
negative regulation of protein phosphorylationGO:00019331260.013
negative regulation of cellular protein metabolic processGO:00322692470.013
positive regulation of viral genome replicationGO:004507020.013
organic anion transportGO:00157111370.013
angiogenesisGO:00015252010.013
anatomical structure homeostasisGO:00602491450.013
deoxyribonucleotide catabolic processGO:000926450.013
heart processGO:0003015940.013
negative regulation of protein metabolic processGO:00512482820.013
base excision repairGO:000628490.013
organ growthGO:00352651170.013
reciprocal meiotic recombinationGO:0007131160.013
positive regulation of mapk cascadeGO:00434101700.013
cellular response to hexose stimulusGO:0071331470.013
b cell activationGO:00421131610.013
g1 s transition of mitotic cell cycleGO:0000082570.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
mrna metabolic processGO:0016071840.013
chromosome condensationGO:0030261100.013
chromosome movement towards spindle poleGO:005130530.013
protein localization to chromosome centromeric regionGO:007145910.012
striated muscle tissue developmentGO:00147062930.012
regulation of cell activationGO:00508652890.012
rna processingGO:00063961050.012
protein modification by small protein conjugationGO:00324461870.012
cognitionGO:00508901490.012
positive regulation of ubiquitin protein transferase activityGO:005144340.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
regulation of homeostatic processGO:00328441820.012
response to reactive oxygen speciesGO:0000302560.012
regulation of purine nucleotide catabolic processGO:00331211220.012
peptidyl tyrosine modificationGO:00182121450.012
muscle tissue developmentGO:00605373080.012
negative regulation of hydrolase activityGO:0051346710.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
regulation of protein processingGO:0070613960.012
peptidyl tyrosine phosphorylationGO:00181081430.012
wnt signaling pathwayGO:00160551880.012
purine containing compound biosynthetic processGO:0072522700.012
placenta developmentGO:00018901400.012
regulation of purine nucleotide metabolic processGO:19005421690.012
response to radiationGO:00093141650.012
locomotory behaviorGO:00076261950.012
metaphase plate congressionGO:005131020.012
response to light stimulusGO:00094161350.012
alpha amino acid biosynthetic processGO:1901607150.012
regulation of protein kinase activityGO:00458592320.012
positive regulation of cell deathGO:00109422240.012
negative regulation of cytoskeleton organizationGO:0051494360.012
regulation of protein transportGO:00512231630.012
intracellular protein transportGO:00068862040.012
apoptotic mitochondrial changesGO:0008637480.012
innate immune responseGO:00450871570.011
regulation of hormone levelsGO:00108172110.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.011
mitotic centrosome separationGO:000710040.011
amide transportGO:00428861380.011
purine nucleobase biosynthetic processGO:000911330.011
rna interferenceGO:001624620.011
neuron deathGO:00709971540.011
response to growth factorGO:00708481980.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
alpha amino acid metabolic processGO:1901605590.011
positive regulation of transferase activityGO:00513471670.011
hexose metabolic processGO:0019318980.011
regulation of nucleotide metabolic processGO:00061401690.011
cell activation involved in immune responseGO:00022631260.011
lipid biosynthetic processGO:00086101790.011
wound healingGO:00420601570.011
epithelial tube formationGO:00721751300.011
dendrite developmentGO:00163581150.011
regulation of cytoplasmic transportGO:19036491120.011
striated muscle cell developmentGO:00550021250.011
t cell differentiationGO:00302171740.011
negative regulation of protein maturationGO:1903318790.011
activation of anaphase promoting complex activityGO:005148810.011
negative regulation of organelle organizationGO:0010639900.011
positive regulation of cell developmentGO:00107202370.011
regulation of lymphocyte proliferationGO:00506701170.011
response to extracellular stimulusGO:00099911270.011
respiratory tube developmentGO:00303231670.011
leukocyte proliferationGO:00706611720.010
regulation of intracellular transportGO:00323861590.010
regulation of lipid metabolic processGO:00192161180.010
response to molecule of bacterial originGO:00022371430.010
rna catabolic processGO:0006401290.010
myofibril assemblyGO:0030239340.010
guanosine containing compound catabolic processGO:19010691440.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
stress activated mapk cascadeGO:0051403800.010
metal ion homeostasisGO:00550651890.010
cellular response to oxidative stressGO:0034599760.010
neural tube formationGO:00018411080.010
epithelial cell proliferationGO:00506731740.010
rhythmic processGO:00485111740.010
lymphocyte homeostasisGO:0002260640.010
humoral immune responseGO:0006959570.010
positive regulation of neuron projection developmentGO:0010976790.010
protein secretionGO:00093061110.010
oogenesisGO:0048477560.010
reactive oxygen species metabolic processGO:0072593840.010
liver developmentGO:0001889660.010
peptidyl threonine phosphorylationGO:0018107310.010
cardiocyte differentiationGO:0035051870.010
cellular response to lipopolysaccharideGO:0071222770.010

Tk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.104
inherited metabolic disorderDOID:65500.104
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.016
gastrointestinal system cancerDOID:311900.014
organ system cancerDOID:005068600.014
intestinal cancerDOID:1015500.011
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011
carbohydrate metabolic disorderDOID:297800.010