Mus musculus

15 known processes

Mfn1

mitofusin 1

(Aliases: D3Ertd265e,HR2,KIAA4032,6330416C07Rik,mKIAA4032,2310002F04Rik)

Mfn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heterocycle catabolic processGO:00467002800.160
organonitrogen compound catabolic processGO:19015652640.139
nucleoside triphosphate metabolic processGO:00091412300.128
purine nucleoside metabolic processGO:00422782410.125
nucleobase containing small molecule metabolic processGO:00550863520.123
nucleoside phosphate catabolic processGO:19012922220.120
membrane organizationGO:00610242450.118
purine ribonucleotide metabolic processGO:00091502900.112
organophosphate catabolic processGO:00464342320.100
purine nucleoside triphosphate metabolic processGO:00091442260.091
ribonucleotide metabolic processGO:00092592910.091
ribose phosphate metabolic processGO:00196932910.091
ribonucleoside triphosphate catabolic processGO:00092031990.089
organic cyclic compound catabolic processGO:19013612950.085
ribonucleotide catabolic processGO:00092612080.082
purine ribonucleoside triphosphate metabolic processGO:00092052200.079
aromatic compound catabolic processGO:00194392860.078
cellular nitrogen compound catabolic processGO:00442702800.075
carbohydrate derivative catabolic processGO:19011362310.075
cellular amino acid metabolic processGO:00065201030.075
purine nucleotide catabolic processGO:00061952110.070
nucleotide catabolic processGO:00091662170.067
actin cytoskeleton organizationGO:00300362200.066
ribonucleoside triphosphate metabolic processGO:00091992200.066
glycosyl compound catabolic processGO:19016582060.064
nucleoside phosphate metabolic processGO:00067533380.063
small gtpase mediated signal transductionGO:0007264970.063
nucleoside catabolic processGO:00091642060.063
purine ribonucleoside triphosphate catabolic processGO:00092071990.062
purine containing compound catabolic processGO:00725232130.061
purine ribonucleotide catabolic processGO:00091542080.059
regulation of cellular catabolic processGO:00313292420.059
purine ribonucleoside catabolic processGO:00461302050.059
purine nucleoside triphosphate catabolic processGO:00091462030.058
purine ribonucleoside metabolic processGO:00461282410.058
purine nucleoside catabolic processGO:00061522050.058
nucleotide metabolic processGO:00091173320.057
nucleoside metabolic processGO:00091162460.057
nucleoside triphosphate catabolic processGO:00091432050.055
purine nucleotide metabolic processGO:00061633020.055
coenzyme metabolic processGO:0006732520.054
macromolecule catabolic processGO:00090572810.054
positive regulation of cellular amino acid metabolic processGO:004576430.053
regulation of cellular ketone metabolic processGO:0010565660.053
ribonucleoside catabolic processGO:00424542060.053
negative regulation of cellular protein metabolic processGO:00322692470.051
glycosyl compound metabolic processGO:19016572460.051
regulation of membrane potentialGO:00423911920.051
regulation of mitochondrial fissionGO:009014030.050
Fly
apoptotic signaling pathwayGO:00971903060.049
purine containing compound metabolic processGO:00725213110.049
cellular macromolecule catabolic processGO:00442652060.049
regulation of organelle organizationGO:00330432890.047
Fly
protein catabolic processGO:00301632210.047
cellular ketone metabolic processGO:0042180840.047
ras protein signal transductionGO:0007265770.046
positive regulation of cellular catabolic processGO:00313311480.046
cation transportGO:00068123990.045
protein localization to organelleGO:00333651850.045
mitochondrion organizationGO:00070051340.044
ion transmembrane transportGO:00342203610.044
transmembrane transportGO:00550854120.044
transmission of nerve impulseGO:0019226760.043
negative regulation of phosphate metabolic processGO:00459361840.042
p38mapk cascadeGO:003806640.041
amine metabolic processGO:0009308450.040
ribonucleoside metabolic processGO:00091192450.040
regulation of cellular amino acid metabolic processGO:000652150.040
response to organonitrogen compoundGO:00102432460.039
regulation of transferase activityGO:00513382630.039
cellular amine metabolic processGO:0044106440.038
positive regulation of cellular amine metabolic processGO:003324050.037
neuronal action potentialGO:0019228540.037
response to growth factorGO:00708481980.037
mapk cascadeGO:00001652810.036
regulation of kinase activityGO:00435492490.036
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.036
positive regulation of protein modification processGO:00314012990.036
negative regulation of immune system processGO:00026832090.035
regulation of cellular response to stressGO:00801351590.034
regulation of apoptotic signaling pathwayGO:20012331970.034
negative regulation of molecular functionGO:00440922580.034
regulation of cellular amine metabolic processGO:0033238200.034
regulation of hydrolase activityGO:00513362460.034
multicellular organismal signalingGO:0035637910.034
response to oxidative stressGO:00069791230.033
negative regulation of phosphorus metabolic processGO:00105631840.033
guanosine containing compound catabolic processGO:19010691440.033
inorganic cation transmembrane transportGO:00986622070.033
response to endoplasmic reticulum stressGO:0034976530.033
Fly
ubiquitin dependent protein catabolic processGO:00065111290.033
regulation of ion transmembrane transportGO:00347651190.031
gtp metabolic processGO:00460391440.031
nitrogen compound transportGO:00717052710.030
cellular lipid metabolic processGO:00442553230.030
translationGO:0006412930.030
dna metabolic processGO:00062593030.029
positive regulation of organelle organizationGO:00106381280.029
Fly
intracellular protein transportGO:00068862040.029
negative regulation of intracellular signal transductionGO:19025321670.029
spermatogenesisGO:00072832840.029
dephosphorylationGO:00163111290.029
cellular response to growth factor stimulusGO:00713631970.029
homeostasis of number of cellsGO:00488722100.029
action potentialGO:0001508780.029
negative regulation of protein modification processGO:00314001630.028
monocarboxylic acid metabolic processGO:00327871910.028
regulation of nucleotide metabolic processGO:00061401690.027
regulation of ion transportGO:00432692150.027
inorganic ion transmembrane transportGO:00986602340.027
protein localization to nucleusGO:00345041210.027
muscle cell differentiationGO:00426922610.027
rho protein signal transductionGO:0007266320.027
gtp catabolic processGO:00061841430.027
regulation of cell activationGO:00508652890.027
guanosine containing compound metabolic processGO:19010681440.027
establishment of mitochondrion localizationGO:005165440.027
protein localization to membraneGO:00726571080.026
cell type specific apoptotic processGO:00972852680.026
cytoplasmic transportGO:00164822340.026
regulation of protein kinase activityGO:00458592320.026
cellular response to organonitrogen compoundGO:00714171450.026
male gamete generationGO:00482322850.025
organelle fissionGO:00482851700.025
Fly
cation transmembrane transportGO:00986552660.025
early endosome to late endosome transportGO:004502220.025
endocytosisGO:00068971680.025
cellular homeostasisGO:00197252400.025
muscle tissue developmentGO:00605373080.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.025
regulation of purine nucleotide catabolic processGO:00331211220.024
positive regulation of hydrolase activityGO:00513451480.024
immune effector processGO:00022523210.024
cytokine productionGO:00018163190.024
regulation of protein localizationGO:00328802310.024
regulation of nucleotide catabolic processGO:00308111220.024
cellularizationGO:000734910.024
negative regulation of phosphorylationGO:00423261660.024
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.024
regulation of protein serine threonine kinase activityGO:00719001570.023
carbohydrate metabolic processGO:00059752300.023
multicellular organism growthGO:00352641610.023
Worm
ensheathment of neuronsGO:0007272760.023
maintenance of locationGO:0051235890.023
negative regulation of interferon beta productionGO:003268830.022
regulation of ras protein signal transductionGO:00465781140.022
cellular chemical homeostasisGO:00550822150.022
negative regulation of cell proliferationGO:00082852960.022
protein localization to plasma membraneGO:0072659570.022
microtubule based processGO:00070172360.022
regulation of purine nucleotide metabolic processGO:19005421690.022
cell adhesionGO:00071553290.022
protein processingGO:00164851630.021
negative regulation of protein phosphorylationGO:00019331260.021
regulation of transmembrane transportGO:00347621280.021
negative regulation of protein metabolic processGO:00512482820.021
positive regulation of purine nucleotide metabolic processGO:19005441140.021
regulation of mapk cascadeGO:00434082480.021
positive regulation of protein phosphorylationGO:00019342420.021
morphogenesis of embryonic epitheliumGO:00163311590.021
synaptic transmissionGO:00072683290.021
very long chain fatty acid catabolic processGO:004276020.020
organelle localizationGO:00516401790.020
locomotory behaviorGO:00076261950.020
Fly
regulation of synaptic growth at neuromuscular junctionGO:000858240.020
reactive oxygen species metabolic processGO:0072593840.020
synapse organizationGO:00508081250.020
regulation of defense responseGO:00313472330.020
intrinsic apoptotic signaling pathwayGO:00971931320.020
regulation of cell cycleGO:00517262810.020
regulation of lymphocyte activationGO:00512492400.020
defense response to other organismGO:00985421970.020
regulation of cytokine productionGO:00018172660.020
nucleocytoplasmic transportGO:00069131390.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
protein modification by small protein conjugation or removalGO:00706472070.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
establishment of organelle localizationGO:00516561220.020
regulation of peptide transportGO:0090087910.020
generation of precursor metabolites and energyGO:00060911030.019
mitochondrion transport along microtubuleGO:004749730.019
positive regulation of nucleoside metabolic processGO:0045979910.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.019
regulation of mitotic cell cycleGO:00073461260.019
positive regulation of cell deathGO:00109422240.019
regulation of secretion by cellGO:19035302490.019
response to transforming growth factor betaGO:0071559880.019
negative regulation of cellular component organizationGO:00511291940.019
purine ribonucleoside monophosphate metabolic processGO:0009167800.019
regulation of nucleoside metabolic processGO:00091181300.018
protein modification by small protein conjugationGO:00324461870.018
ribonucleoside monophosphate metabolic processGO:0009161800.018
cytoskeleton dependent intracellular transportGO:0030705500.018
negative regulation of cellular response to growth factor stimulusGO:0090288460.018
positive regulation of growthGO:00459271040.018
Worm
multicellular organismal homeostasisGO:00488711640.018
regulation of homeostatic processGO:00328441820.018
leukocyte differentiationGO:00025213420.018
regulation of anatomical structure sizeGO:00900661780.018
atp metabolic processGO:0046034750.018
cofactor metabolic processGO:0051186800.018
striated muscle tissue developmentGO:00147062930.018
endomembrane system organizationGO:00102561470.018
Fly
positive regulation of gtp catabolic processGO:0033126850.018
cation homeostasisGO:00550802120.018
purine nucleoside monophosphate catabolic processGO:0009128580.018
cellular response to hormone stimulusGO:00328701500.017
positive regulation of purine nucleotide catabolic processGO:0033123880.017
oxidation reduction processGO:00551143420.017
nucleoside monophosphate metabolic processGO:0009123850.017
protein ubiquitinationGO:00165671710.017
plasma membrane organizationGO:0007009900.017
purine ribonucleoside monophosphate catabolic processGO:0009169570.017
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.017
sensory perceptionGO:00076002450.017
cellular carbohydrate metabolic processGO:00442621190.017
digestive system developmentGO:00551232000.017
positive regulation of nucleotide catabolic processGO:0030813880.017
thioester metabolic processGO:0035383190.017
myelinationGO:0042552740.017
peptidyl amino acid modificationGO:00181933360.016
urogenital system developmentGO:00016552610.016
positive regulation of programmed cell deathGO:00430682180.016
sequestering of calcium ionGO:0051208180.016
response to radiationGO:00093141650.016
posttranscriptional regulation of gene expressionGO:00106081550.016
negative regulation of apoptotic signaling pathwayGO:20012341040.016
response to inorganic substanceGO:0010035960.016
regulation of protein transportGO:00512231630.016
telencephalon developmentGO:00215371860.016
t cell activationGO:00421102890.016
renal system developmentGO:00720012250.016
regulation of proteolysisGO:00301621640.016
cellular component assembly involved in morphogenesisGO:00109271390.016
digestive tract morphogenesisGO:00485461470.016
nucleoside monophosphate catabolic processGO:0009125590.016
stress activated mapk cascadeGO:0051403800.016
amide transportGO:00428861380.016
g protein coupled receptor signaling pathwayGO:00071862430.016
cellular ion homeostasisGO:00068731650.016
mitotic cell cycleGO:00002781950.015
fat cell differentiationGO:00454441600.015
regulation of establishment of protein localizationGO:00702011810.015
negative regulation of multi organism processGO:0043901680.015
forebrain developmentGO:00309003020.015
divalent metal ion transportGO:00708381720.015
sequestering of metal ionGO:0051238190.015
neuron apoptotic processGO:00514021420.015
axon ensheathmentGO:0008366760.015
microtubule cytoskeleton organizationGO:00002261570.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
stress activated protein kinase signaling cascadeGO:0031098810.015
gastrulationGO:00073691160.015
neuron deathGO:00709971540.015
regulation of t cell activationGO:00508631700.015
lipid biosynthetic processGO:00086101790.015
reactive oxygen species biosynthetic processGO:190340980.015
regulation of cellular component sizeGO:00325351210.015
cellular response to cytokine stimulusGO:00713451890.015
epithelial tube morphogenesisGO:00605623030.015
cofactor biosynthetic processGO:0051188410.015
transforming growth factor beta receptor signaling pathwayGO:0007179710.014
anatomical structure homeostasisGO:00602491450.014
chromatin organizationGO:00063252060.014
acetyl coa biosynthetic process from pyruvateGO:000608630.014
regulation of p38mapk cascadeGO:190074430.014
divalent inorganic cation transportGO:00725111780.014
positive regulation of nucleotide metabolic processGO:00459811140.014
regulation of cellular response to growth factor stimulusGO:0090287820.014
nuclear transportGO:00511691390.014
anion transmembrane transportGO:0098656710.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
embryonic epithelial tube formationGO:00018381300.014
regulation of interleukin 8 productionGO:003267730.014
positive regulation of transferase activityGO:00513471670.014
neural precursor cell proliferationGO:00613511210.014
proteasomal protein catabolic processGO:0010498980.014
adult behaviorGO:00305341350.014
Fly
regulation of cellular component biogenesisGO:00440871810.014
peptide transportGO:00158331330.014
wnt signaling pathwayGO:00160551880.014
protein maturationGO:00516041760.014
lymphocyte differentiationGO:00300982420.014
regionalizationGO:00030023370.014
interleukin 8 productionGO:003263740.014
lipid localizationGO:00108761260.013
lymphocyte proliferationGO:00466511640.013
cell activation involved in immune responseGO:00022631260.013
regulation of lymphocyte proliferationGO:00506701170.013
leukocyte mediated immunityGO:00024431740.013
organonitrogen compound biosynthetic processGO:19015661920.013
leukocyte proliferationGO:00706611720.013
kidney developmentGO:00018222130.013
regulation of intracellular transportGO:00323861590.013
regulation of map kinase activityGO:00434051200.013
small molecule biosynthetic processGO:00442831320.013
cellular protein complex assemblyGO:00436231160.013
neural tube formationGO:00018411080.013
camera type eye developmentGO:00430102660.013
Mouse
positive regulation of protein kinase activityGO:00458601440.013
establishment of protein localization to organelleGO:00725941180.013
cellular response to peptideGO:1901653920.013
ribonucleoside monophosphate catabolic processGO:0009158570.013
positive regulation of kinase activityGO:00336741550.013
thioester biosynthetic processGO:003538470.013
protein targetingGO:00066051430.013
negative regulation of defense responseGO:0031348770.013
regulation of cell projection organizationGO:00313442060.013
jnk cascadeGO:0007254720.013
regulation of cytoplasmic transportGO:19036491120.013
gland developmentGO:00487323300.013
regulation of actin filament based processGO:0032970990.013
axonogenesisGO:00074092740.013
mitochondrion degradationGO:000042230.013
regulation of cytoskeleton organizationGO:00514931220.013
cellular protein catabolic processGO:00442571550.013
leukocyte homeostasisGO:0001776790.013
regulation of secretionGO:00510462740.013
mitochondrial translationGO:003254340.013
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.012
positive regulation of mitochondrion organizationGO:0010822170.012
Fly
lipid homeostasisGO:0055088630.012
metal ion homeostasisGO:00550651890.012
cell junction organizationGO:0034330770.012
organelle fusionGO:0048284280.012
chromatin modificationGO:00165681870.012
response to insulinGO:00328681000.012
compound eye developmentGO:004874910.012
coenzyme biosynthetic processGO:0009108230.012
carboxylic acid biosynthetic processGO:0046394860.012
pyridine containing compound catabolic processGO:007252640.012
blood vessel morphogenesisGO:00485142850.012
cell agingGO:0007569350.012
embryonic organ morphogenesisGO:00485622760.012
blood circulationGO:00080151950.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
skeletal muscle organ developmentGO:00605381630.012
microtubule based transportGO:0010970500.012
mitotic cell cycle processGO:19030471590.012
regulation of ras gtpase activityGO:0032318880.012
monocarboxylic acid biosynthetic processGO:0072330610.012
response to peptideGO:19016521360.012
circulatory system processGO:00030131970.012
negative regulation of mapk cascadeGO:0043409650.012
response to organic cyclic compoundGO:00140701980.012
digestive tract developmentGO:00485651900.012
modification dependent macromolecule catabolic processGO:00436321330.012
regulation of metal ion transportGO:00109591060.012
response to reactive oxygen speciesGO:0000302560.012
regulation of cell cycle processGO:00105641600.012
protein acylationGO:0043543640.012
cell recognitionGO:0008037830.012
spermatid differentiationGO:00485151150.012
tube formationGO:00351481400.012
carboxylic acid transportGO:00469421000.012
engulfment of apoptotic cellGO:004365230.012
negative regulation of mitotic cell cycleGO:0045930580.011
glucose homeostasisGO:00425931280.011
histone modificationGO:00165701590.011
defense response to virusGO:0051607680.011
actin filament organizationGO:00070151130.011
developmental growth involved in morphogenesisGO:00605601380.011
defense response to bacteriumGO:00427421190.011
negative regulation of cellular amine metabolic processGO:003323910.011
negative regulation of kinase activityGO:0033673810.011
single organism nuclear importGO:1902593950.011
neuromuscular processGO:0050905990.011
neural tube closureGO:0001843900.011
regulation of t cell proliferationGO:0042129920.011
inflammatory responseGO:00069542440.011
ossificationGO:00015032160.011
negative regulation of growthGO:0045926990.011
tissue homeostasisGO:00018941150.011
spermatid developmentGO:00072861080.011
regulation of actin cytoskeleton organizationGO:0032956840.011
regulation of epithelial cell proliferationGO:00506781410.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
phospholipid metabolic processGO:0006644870.011
glycerophospholipid metabolic processGO:0006650710.011
epithelial tube formationGO:00721751300.011
erk1 and erk2 cascadeGO:0070371770.011
dna repairGO:00062811070.011
regulation of cell motilityGO:20001452360.011
negative regulation of organelle organizationGO:0010639900.011
response to uvGO:0009411440.011
carbohydrate derivative biosynthetic processGO:19011371830.011
response to acid chemicalGO:00011011110.011
positive regulation of gtpase activityGO:0043547850.011
regulation of mitochondrion organizationGO:0010821270.011
Fly
sulfur compound metabolic processGO:00067901000.011
regulation of multi organism processGO:00439001110.011
protein polymerizationGO:0051258570.011
regulation of hormone levelsGO:00108172110.011
positive regulation of lymphocyte activationGO:00512511400.011
organic hydroxy compound metabolic processGO:19016152030.011
regulation of lipid metabolic processGO:00192161180.011
single organism cell adhesionGO:00986021560.011
protein oligomerizationGO:0051259670.011
innate immune responseGO:00450871570.011
positive regulation of cell activationGO:00508671580.011
positive regulation of ras gtpase activityGO:0032320650.011
regulation of jnk cascadeGO:0046328620.011
response to peptide hormoneGO:00434341270.011
cellular response to dna damage stimulusGO:00069742070.010
establishment of blood nerve barrierGO:000806530.010
epithelial cell proliferationGO:00506731740.010
regulation of gtp catabolic processGO:00331241130.010
acylglycerol metabolic processGO:0006639550.010
negative regulation of transferase activityGO:0051348850.010
actin polymerization or depolymerizationGO:0008154540.010
covalent chromatin modificationGO:00165691630.010
regulation of response to woundingGO:19030341890.010
regulation of leukocyte differentiationGO:19021051590.010
regulation of intracellular protein transportGO:0033157820.010
epithelial cell developmentGO:00020641590.010
microtubule based movementGO:0007018840.010
organic acid biosynthetic processGO:0016053860.010
negative regulation of immune effector processGO:0002698550.010
single organismal cell cell adhesionGO:00163371310.010
protein importGO:00170381010.010
t cell proliferationGO:00420981200.010
cellular metal ion homeostasisGO:00068751510.010
tube closureGO:0060606910.010
pallium developmentGO:00215431200.010
protein import into nucleusGO:0006606950.010
regulation of ion transmembrane transporter activityGO:0032412540.010
organic hydroxy compound transportGO:0015850930.010
negative regulation of cell developmentGO:00107211690.010
organic anion transportGO:00157111370.010
nuclear importGO:0051170950.010

Mfn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
musculoskeletal system diseaseDOID:1700.020
sensory system diseaseDOID:005015500.018
immune system diseaseDOID:291400.015
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
neurodegenerative diseaseDOID:128900.012
central nervous system diseaseDOID:33100.012
hematopoietic system diseaseDOID:7400.011