Mus musculus

99 known processes

Timeless

timeless homolog (Drosophila)

(Aliases: tim,C77407,Debt69)

Timeless biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna dependent dna replication maintenance of fidelityGO:004500530.987
cellular response to dna damage stimulusGO:00069742070.975
dna repairGO:00062811070.955
dna recombinationGO:0006310920.950
dna biosynthetic processGO:0071897220.937
dna metabolic processGO:00062593030.936
base excision repairGO:000628490.883
dna dependent dna replicationGO:0006261240.873
dna replicationGO:0006260520.867
double strand break repair via homologous recombinationGO:0000724210.857
intra s dna damage checkpointGO:003157340.829
regulation of cell cycle processGO:00105641600.820
Worm
recombinational repairGO:0000725210.814
meiotic nuclear divisionGO:00071261150.808
Worm
rna dependent dna replicationGO:000627830.800
translesion synthesisGO:001998510.764
double strand break repairGO:0006302480.691
nuclear dna replicationGO:003326030.631
nucleotide excision repairGO:0006289130.586
regulation of transcription by chromatin organizationGO:003440100.552
meiotic cell cycle processGO:1903046770.516
Worm
dna integrity checkpointGO:0031570280.515
Fly
dna geometric changeGO:003239270.502
regulation of mitotic cell cycle phase transitionGO:1901990730.463
nucleobase containing small molecule metabolic processGO:00550863520.454
dna unwinding involved in dna replicationGO:000626850.446
receptor mediated endocytosisGO:0006898510.411
nuclear divisionGO:00002801580.372
Worm
heterochromatin organizationGO:007082840.359
somatic diversification of immune receptors via somatic mutationGO:000256680.334
organelle fissionGO:00482851700.311
Worm
dna duplex unwindingGO:003250870.276
mitotic sister chromatid cohesionGO:000706410.266
Worm
purine nucleoside triphosphate metabolic processGO:00091442260.264
meiotic cell cycleGO:00513211220.249
Worm
nucleoside monophosphate metabolic processGO:0009123850.238
purine nucleoside catabolic processGO:00061522050.230
meiosis iGO:0007127600.223
purine ribonucleotide metabolic processGO:00091502900.217
chromatin organizationGO:00063252060.216
negative regulation of cell cycle phase transitionGO:1901988480.210
nucleoside metabolic processGO:00091162460.204
intrinsic apoptotic signaling pathwayGO:00971931320.203
negative regulation of mitotic cell cycleGO:0045930580.195
purine ribonucleoside catabolic processGO:00461302050.195
mitotic cell cycleGO:00002781950.190
Worm
dna endoreduplicationGO:004202340.190
dna replication initiationGO:000627050.189
ribonucleoside monophosphate catabolic processGO:0009158570.188
purine ribonucleoside metabolic processGO:00461282410.184
ribonucleoside triphosphate catabolic processGO:00092031990.184
aromatic compound catabolic processGO:00194392860.183
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.178
development of primary sexual characteristicsGO:00451371430.172
purine containing compound metabolic processGO:00725213110.166
carbohydrate derivative catabolic processGO:19011362310.163
regulation of cell cycle g2 m phase transitionGO:1902749100.157
regulation of hydrolase activityGO:00513362460.154
purine containing compound catabolic processGO:00725232130.153
purine ribonucleoside monophosphate catabolic processGO:0009169570.150
regulation of mitotic cell cycleGO:00073461260.146
purine ribonucleoside triphosphate catabolic processGO:00092071990.144
dna damage checkpointGO:0000077260.142
Fly
sister chromatid cohesionGO:0007062120.136
Worm
atp catabolic processGO:0006200550.132
negative regulation of gene expression epigeneticGO:0045814150.129
organic cyclic compound catabolic processGO:19013612950.127
purine ribonucleotide catabolic processGO:00091542080.127
organonitrogen compound catabolic processGO:19015652640.126
somatic diversification of immune receptorsGO:0002200530.125
dna replication checkpointGO:000007620.125
ribonucleotide metabolic processGO:00092592910.117
ribonucleoside catabolic processGO:00424542060.117
mitotic cell cycle processGO:19030471590.116
Worm
purine nucleoside metabolic processGO:00422782410.113
negative regulation of nucleoside metabolic processGO:0045978110.109
purine nucleotide catabolic processGO:00061952110.105
nucleotide metabolic processGO:00091173320.105
double strand break repair via nonhomologous end joiningGO:0006303100.103
purine ribonucleoside triphosphate metabolic processGO:00092052200.102
ribonucleotide catabolic processGO:00092612080.098
cellular nitrogen compound catabolic processGO:00442702800.097
cell cycle checkpointGO:0000075470.097
Fly
purine nucleotide metabolic processGO:00061633020.095
organophosphate catabolic processGO:00464342320.094
rna catabolic processGO:0006401290.092
purine nucleoside triphosphate catabolic processGO:00091462030.091
regulation of cell cycle phase transitionGO:1901987770.089
cellular amino acid metabolic processGO:00065201030.088
negative regulation of mitotic cell cycle phase transitionGO:1901991450.087
lateral inhibitionGO:004633110.086
negative regulation of chromatin silencingGO:003193610.084
heterocycle catabolic processGO:00467002800.084
somatic recombination of immunoglobulin gene segmentsGO:0016447420.084
glycosyl compound catabolic processGO:19016582060.082
organism emergence from protective structureGO:007168440.081
regulation of dna replicationGO:0006275170.081
response to light stimulusGO:00094161350.079
Fly
cellular response to cytokine stimulusGO:00713451890.078
gene silencingGO:0016458380.078
ribonucleoside monophosphate metabolic processGO:0009161800.074
nucleoside catabolic processGO:00091642060.073
nucleoside triphosphate metabolic processGO:00091412300.070
positive regulation of hydrolase activityGO:00513451480.070
ribose phosphate metabolic processGO:00196932910.069
cell cycle g1 s phase transitionGO:0044843570.067
nucleoside phosphate catabolic processGO:19012922220.067
cell divisionGO:00513011200.061
hatchingGO:003518840.060
endocytosisGO:00068971680.060
glycosyl compound metabolic processGO:19016572460.060
ribonucleoside metabolic processGO:00091192450.059
gonad developmentGO:00084061410.059
purine nucleoside monophosphate catabolic processGO:0009128580.058
nucleoside phosphate metabolic processGO:00067533380.057
ribonucleoside triphosphate metabolic processGO:00091992200.057
negative regulation of cell cycleGO:00457861230.056
nucleotide catabolic processGO:00091662170.056
nucleoside triphosphate catabolic processGO:00091432050.055
inner cell mass cell proliferationGO:0001833150.054
regulation of nucleoside metabolic processGO:00091181300.053
nucleic acid phosphodiester bond hydrolysisGO:0090305490.051
apoptotic signaling pathwayGO:00971903060.050
immunoglobulin productionGO:0002377730.048
production of molecular mediator of immune responseGO:00024401030.048
postreplication repairGO:000630150.046
protein modification by small protein conjugation or removalGO:00706472070.046
nucleus organizationGO:0006997450.046
regulation of organelle organizationGO:00330432890.045
Worm
negative regulation of nucleotide catabolic processGO:003081290.044
reciprocal dna recombinationGO:0035825160.043
meiotic chromosome separationGO:005130750.042
regulation of cellular catabolic processGO:00313292420.042
g2 m transition of mitotic cell cycleGO:0000086200.042
somatic hypermutation of immunoglobulin genesGO:001644670.042
microtubule cytoskeleton organizationGO:00002261570.042
purine nucleoside monophosphate metabolic processGO:0009126810.037
regulation of dna dependent dna replicationGO:009032980.037
fatty acid homeostasisGO:005508950.036
macromolecule catabolic processGO:00090572810.036
negative regulation of cell proliferationGO:00082852960.036
somatic diversification of immunoglobulinsGO:0016445430.035
regulation of dna dependent dna replication initiationGO:003017430.034
homeostasis of number of cellsGO:00488722100.034
response to purine containing compoundGO:0014074280.034
sister chromatid segregationGO:0000819200.034
Worm
chromosome segregationGO:0007059480.033
Worm
mitotic cell cycle checkpointGO:0007093310.033
purine ribonucleoside monophosphate metabolic processGO:0009167800.033
membrane organizationGO:00610242450.032
response to radiationGO:00093141650.032
Fly
lipid homeostasisGO:0055088630.032
regulation of g2 m transition of mitotic cell cycleGO:0010389100.031
negative regulation of molecular functionGO:00440922580.031
Fly
negative regulation of cell cycle processGO:0010948690.031
lymphocyte mediated immunityGO:00024491390.030
negative regulation of protein modification processGO:00314001630.029
gene conversionGO:003582220.029
negative regulation of atpase activityGO:003278020.028
camera type eye developmentGO:00430102660.028
intracellular mrna localizationGO:000829840.028
genitalia developmentGO:0048806370.028
b cell activationGO:00421131610.028
regulation of purine nucleotide metabolic processGO:19005421690.028
striated muscle myosin thick filament assemblyGO:007168810.027
response to interleukin 4GO:0070670230.027
regulation of anatomical structure sizeGO:00900661780.027
nucleosome assemblyGO:000633470.026
protein ubiquitinationGO:00165671710.026
regulation of nucleotide metabolic processGO:00061401690.026
negative regulation of gene silencingGO:006096920.026
carboxylic acid biosynthetic processGO:0046394860.025
response to organonitrogen compoundGO:00102432460.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.024
negative regulation of purine nucleotide catabolic processGO:003312290.024
l amino acid transportGO:0015807320.024
negative regulation of hydrolase activityGO:0051346710.023
cellular ketone metabolic processGO:0042180840.023
response to organic cyclic compoundGO:00140701980.023
atp metabolic processGO:0046034750.023
cell activation involved in immune responseGO:00022631260.022
amine metabolic processGO:0009308450.022
female meiotic divisionGO:0007143210.022
cellular response to organonitrogen compoundGO:00714171450.022
cellular amine metabolic processGO:0044106440.021
regulation of bindingGO:00510981110.021
Fly
non recombinational repairGO:0000726100.021
regulation of cell divisionGO:0051302760.021
telomere maintenance via telomeraseGO:000700410.021
regulation of cellular amine metabolic processGO:0033238200.021
macromolecule methylationGO:00434141200.020
protein dna complex subunit organizationGO:0071824280.020
regulation of cellular response to stressGO:00801351590.020
anion homeostasisGO:0055081160.020
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.020
blood vessel morphogenesisGO:00485142850.020
female gamete generationGO:0007292740.020
mitotic recombinationGO:000631230.020
regulation of purine nucleotide catabolic processGO:00331211220.019
g1 s transition of mitotic cell cycleGO:0000082570.018
immune effector processGO:00022523210.018
regulation of transferase activityGO:00513382630.018
maintenance of locationGO:0051235890.017
cation transportGO:00068123990.017
negative regulation of phosphorylationGO:00423261660.017
methylationGO:00322591340.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
adaptive immune responseGO:00022501550.017
sensory organ morphogenesisGO:00905962420.017
negative regulation of phosphate metabolic processGO:00459361840.017
regulation of proteolysisGO:00301621640.017
regulation of chromosome organizationGO:0033044830.017
Worm
leukocyte mediated immunityGO:00024431740.017
regulation of nucleotide catabolic processGO:00308111220.016
protein modification by small protein conjugationGO:00324461870.016
male gamete generationGO:00482322850.016
negative regulation of cell developmentGO:00107211690.016
regulation of histone h3 k4 methylationGO:0051569120.016
regulation of protein modification by small protein conjugation or removalGO:1903320570.016
response to ionizing radiationGO:0010212420.016
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.016
nucleoside monophosphate catabolic processGO:0009125590.015
negative regulation of nucleotide metabolic processGO:0045980160.015
response to metal ionGO:0010038470.015
regulation of cytokine productionGO:00018172660.015
negative regulation of protein metabolic processGO:00512482820.015
negative regulation of phosphorus metabolic processGO:00105631840.015
endomembrane system organizationGO:00102561470.015
rhythmic processGO:00485111740.015
l serine metabolic processGO:000656320.015
nitrogen compound transportGO:00717052710.015
regulation of atp metabolic processGO:1903578170.015
digestive system developmentGO:00551232000.014
somatic cell dna recombinationGO:0016444510.014
negative regulation of atp metabolic processGO:190357940.014
chromatin silencingGO:0006342150.014
positive regulation of cellular catabolic processGO:00313311480.014
response to lipopolysaccharideGO:00324961280.014
histone methylationGO:0016571710.014
small molecule biosynthetic processGO:00442831320.014
regulation of apoptotic signaling pathwayGO:20012331970.014
mitotic g2 dna damage checkpointGO:000709580.014
gonad morphogenesisGO:003526210.014
lymphocyte activation involved in immune responseGO:0002285930.013
cytokine productionGO:00018163190.013
positive regulation of cellular amine metabolic processGO:003324050.013
signal transduction by p53 class mediatorGO:0072331510.013
negative regulation of purine nucleotide metabolic processGO:1900543160.013
regulation of actin polymerization or depolymerizationGO:0008064450.013
cell cell signaling involved in cell fate commitmentGO:0045168350.013
leukocyte proliferationGO:00706611720.013
organonitrogen compound biosynthetic processGO:19015661920.013
myosin filament organizationGO:003103330.013
angiogenesisGO:00015252010.013
regulation of protein kinase activityGO:00458592320.013
cell maturationGO:00484691270.013
nucleobase biosynthetic processGO:004611230.013
t cell activationGO:00421102890.013
organic hydroxy compound metabolic processGO:19016152030.013
myosin filament assemblyGO:003103420.013
regulation of cellular amino acid metabolic processGO:000652150.012
actin filament organizationGO:00070151130.012
cellular protein complex assemblyGO:00436231160.012
oxidation reduction processGO:00551143420.012
folic acid containing compound metabolic processGO:000676030.012
blastocyst developmentGO:0001824800.012
leukocyte differentiationGO:00025213420.012
cellular component assembly involved in morphogenesisGO:00109271390.012
digestive tract morphogenesisGO:00485461470.012
regulation of secretionGO:00510462740.012
spermatogenesisGO:00072832840.012
signal transduction involved in dna damage checkpointGO:007242230.012
negative regulation of intracellular signal transductionGO:19025321670.012
regulation of histone modificationGO:0031056560.012
response to testosteroneGO:003357430.012
positive regulation of nucleotide metabolic processGO:00459811140.012
positive regulation of gtpase activityGO:0043547850.012
localization within membraneGO:005166840.012
regulation of gtp catabolic processGO:00331241130.012
digestive tract developmentGO:00485651900.012
base excision repair gap fillingGO:000628730.011
intracellular receptor signaling pathwayGO:0030522740.011
ion transmembrane transportGO:00342203610.011
regulation of cell motilityGO:20001452360.011
leukocyte activation involved in immune responseGO:00023661260.011
circulatory system processGO:00030131970.011
isotype switchingGO:0045190360.011
mitotic sister chromatid segregationGO:0000070140.011
Worm
glial cell differentiationGO:00100011310.011
error prone translesion synthesisGO:004227610.011
monocarboxylic acid metabolic processGO:00327871910.011
divalent metal ion transportGO:00708381720.011
b cell activation involved in immune responseGO:0002312500.011
positive regulation of cell cycle phase transitionGO:1901989170.011
protein localization to organelleGO:00333651850.011
regulation of cellular ketone metabolic processGO:0010565660.011
response to inorganic substanceGO:0010035960.011
cell cycle g2 m phase transitionGO:0044839200.011
lymphocyte differentiationGO:00300982420.011
regulation of leukocyte proliferationGO:00706631210.011
lymphocyte proliferationGO:00466511640.011
stem cell differentiationGO:00488632680.010
forebrain developmentGO:00309003020.010
g0 to g1 transitionGO:004502330.010
blood circulationGO:00080151950.010
gland developmentGO:00487323300.010
regulation of cell cycleGO:00517262810.010
Worm
s adenosylmethionine metabolic processGO:004650020.010
regulation of hormone levelsGO:00108172110.010
cell type specific apoptotic processGO:00972852680.010
purine nucleobase biosynthetic processGO:000911330.010
multicellular organismal homeostasisGO:00488711640.010
Fly
heterochromatin organization involved in chromatin silencingGO:007086810.010

Timeless disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.967
cancerDOID:16200.841
organ system cancerDOID:005068600.818
gastrointestinal system cancerDOID:311900.583
intestinal cancerDOID:1015500.547
large intestine cancerDOID:567200.541
colorectal cancerDOID:925600.255
inherited metabolic disorderDOID:65500.031
disease of metabolismDOID:001466700.031
male reproductive organ cancerDOID:385600.017
reproductive organ cancerDOID:19300.017
central nervous system diseaseDOID:33100.014
disease of anatomical entityDOID:700.014
nervous system diseaseDOID:86300.014