IMP: Integrative Multi-species Prediction

Mus musculus

36 known processes

Ephb6

Eph receptor B6

(Aliases: Cekl,Mep)

Entrez: 13848
Ensembl: ENSMUSG00000029869
UniProtKB: O08644

Process Predictions
Disease Predictions

Ephb6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chemotaxis	GO:0006935	247	0.380	Mouse Worm
epidermis development	GO:0008544	187	0.280
regulation of neuron differentiation	GO:0045664	281	0.250	Mouse
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.248	Mouse
single organismal cell cell adhesion	GO:0016337	131	0.208	Mouse
regulation of transferase activity	GO:0051338	263	0.203	Mouse
ras protein signal transduction	GO:0007265	77	0.198
regulation of kinase activity	GO:0043549	249	0.192	Mouse
purine nucleotide catabolic process	GO:0006195	211	0.188	Mouse
axonogenesis	GO:0007409	274	0.185	Mouse Worm
cell adhesion	GO:0007155	329	0.182	Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.181	Mouse
aromatic compound catabolic process	GO:0019439	286	0.179	Mouse
nucleoside phosphate metabolic process	GO:0006753	338	0.177	Mouse
cellular lipid metabolic process	GO:0044255	323	0.175	Mouse
regionalization	GO:0003002	337	0.174
purine ribonucleoside metabolic process	GO:0046128	241	0.171	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.164	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.162	Mouse
gtp catabolic process	GO:0006184	143	0.152	Mouse
organophosphate catabolic process	GO:0046434	232	0.148	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.145
negative regulation of cell development	GO:0010721	169	0.145	Mouse
regulation of neuron projection development	GO:0010975	169	0.138	Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.136	Mouse
salivary gland development	GO:0007431	37	0.127
regulation of cell projection organization	GO:0031344	206	0.126	Mouse
regulation of organelle organization	GO:0033043	289	0.121	Mouse
ribonucleotide catabolic process	GO:0009261	208	0.120	Mouse
nucleoside triphosphate catabolic process	GO:0009143	205	0.118	Mouse
developmental growth involved in morphogenesis	GO:0060560	138	0.116
purine nucleoside catabolic process	GO:0006152	205	0.113	Mouse
glycosyl compound catabolic process	GO:1901658	206	0.108	Mouse
actin cytoskeleton organization	GO:0030036	220	0.106	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.106	Mouse
positive regulation of mapk cascade	GO:0043410	170	0.103	Mouse
neuron projection guidance	GO:0097485	141	0.102	Mouse Worm
nucleoside metabolic process	GO:0009116	246	0.101	Mouse
regulation of cell adhesion	GO:0030155	154	0.101	Mouse
positive regulation of nervous system development	GO:0051962	221	0.101	Mouse
purine ribonucleoside catabolic process	GO:0046130	205	0.100	Mouse
ribonucleoside metabolic process	GO:0009119	245	0.100	Mouse
purine nucleoside metabolic process	GO:0042278	241	0.099	Mouse
negative regulation of cell projection organization	GO:0031345	56	0.098	Mouse
positive regulation of protein kinase activity	GO:0045860	144	0.098	Mouse
developmental maturation	GO:0021700	193	0.093	Mouse Worm
ribonucleotide metabolic process	GO:0009259	291	0.093	Mouse
positive regulation of protein modification process	GO:0031401	299	0.092	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.091	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.091	Mouse
rho protein signal transduction	GO:0007266	32	0.090
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.089	Mouse
positive regulation of cell death	GO:0010942	224	0.089	Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.088	Mouse
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.088	Mouse
skin development	GO:0043588	220	0.086
morphogenesis of a branching structure	GO:0001763	203	0.086	Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.084	Mouse
regulation of cell migration	GO:0030334	219	0.084	Mouse
regulation of cytoskeleton organization	GO:0051493	122	0.083	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.083	Mouse
ribonucleoside catabolic process	GO:0042454	206	0.083	Mouse
nucleoside catabolic process	GO:0009164	206	0.081	Mouse
tube formation	GO:0035148	140	0.077
cellular response to hormone stimulus	GO:0032870	150	0.076
neural tube development	GO:0021915	160	0.076	Mouse
immune effector process	GO:0002252	321	0.076	Fly
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.075	Mouse
regulation of mapk cascade	GO:0043408	248	0.075	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.074
organic cyclic compound catabolic process	GO:1901361	295	0.074	Mouse
nucleoside phosphate catabolic process	GO:1901292	222	0.074	Mouse
cellular response to organonitrogen compound	GO:0071417	145	0.074
gland development	GO:0048732	330	0.073	Mouse
regulation of anatomical structure size	GO:0090066	178	0.073
negative regulation of molecular function	GO:0044092	258	0.073
nitrogen compound transport	GO:0071705	271	0.073	Mouse
wnt signaling pathway	GO:0016055	188	0.072
purine nucleotide metabolic process	GO:0006163	302	0.071	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.071	Mouse
positive regulation of cytokine production	GO:0001819	174	0.070
microtubule based process	GO:0007017	236	0.070
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.069
forebrain development	GO:0030900	302	0.068	Mouse
mapk cascade	GO:0000165	281	0.067	Mouse
positive regulation of cell development	GO:0010720	237	0.067	Mouse
camera type eye development	GO:0043010	266	0.066	Mouse
purine containing compound catabolic process	GO:0072523	213	0.066	Mouse
regulation of wnt signaling pathway	GO:0030111	123	0.066
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.066	Mouse
regulation of hydrolase activity	GO:0051336	246	0.064	Mouse
neural precursor cell proliferation	GO:0061351	121	0.063	Mouse
cytoplasmic transport	GO:0016482	234	0.062
protein modification by small protein conjugation or removal	GO:0070647	207	0.062
establishment of planar polarity	GO:0001736	28	0.061
epithelial tube morphogenesis	GO:0060562	303	0.061	Mouse
negative regulation of neuron projection development	GO:0010977	50	0.061	Mouse
positive regulation of gtpase activity	GO:0043547	85	0.061
regulation of intracellular transport	GO:0032386	159	0.061
carbohydrate metabolic process	GO:0005975	230	0.061
regulation of cell cycle	GO:0051726	281	0.061
neuron migration	GO:0001764	122	0.060
asymmetric neuroblast division	GO:0055059	1	0.060
skeletal system morphogenesis	GO:0048705	203	0.060
skeletal system development	GO:0001501	356	0.060	Mouse
carbohydrate homeostasis	GO:0033500	128	0.060	Mouse
cellular ketone metabolic process	GO:0042180	84	0.059
positive regulation of neuron differentiation	GO:0045666	141	0.059
wound healing	GO:0042060	157	0.059
response to organonitrogen compound	GO:0010243	246	0.059
regulation of angiogenesis	GO:0045765	81	0.058	Mouse
positive regulation of kinase activity	GO:0033674	155	0.058	Mouse
leukocyte differentiation	GO:0002521	342	0.057	Mouse
ion transmembrane transport	GO:0034220	361	0.056
ribose phosphate metabolic process	GO:0019693	291	0.056	Mouse
protein maturation	GO:0051604	176	0.055
response to peptide	GO:1901652	136	0.055
oocyte axis specification	GO:0007309	2	0.055
establishment of tissue polarity	GO:0007164	28	0.054
single organism cell adhesion	GO:0098602	156	0.054	Mouse
blood vessel morphogenesis	GO:0048514	285	0.054	Mouse
neural tube formation	GO:0001841	108	0.054
non canonical wnt signaling pathway	GO:0035567	33	0.054
cellular response to growth factor stimulus	GO:0071363	197	0.054
positive regulation of programmed cell death	GO:0043068	218	0.054	Mouse
regulation of vasculature development	GO:1901342	88	0.053	Mouse
cell maturation	GO:0048469	127	0.053	Mouse Worm
axon guidance	GO:0007411	141	0.053	Mouse Worm
muscle tissue development	GO:0060537	308	0.053
regulation of body fluid levels	GO:0050878	162	0.052	Mouse
protein processing	GO:0016485	163	0.052
transmembrane transport	GO:0055085	412	0.052
connective tissue development	GO:0061448	179	0.052
regulation of actin cytoskeleton organization	GO:0032956	84	0.052	Mouse
retina development in camera type eye	GO:0060041	119	0.051
tube closure	GO:0060606	91	0.051
regulation of protein kinase activity	GO:0045859	232	0.051	Mouse
negative regulation of nervous system development	GO:0051961	156	0.051	Mouse
lipid transport	GO:0006869	98	0.051
positive regulation of cell projection organization	GO:0031346	95	0.051
cellular response to peptide	GO:1901653	92	0.050
regulation of protein localization	GO:0032880	231	0.050
carbohydrate derivative catabolic process	GO:1901136	231	0.050	Mouse
regulation of vesicle mediated transport	GO:0060627	139	0.049
epithelial cell proliferation	GO:0050673	174	0.049	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.049	Mouse
purine ribonucleotide catabolic process	GO:0009154	208	0.048	Mouse
asymmetric stem cell division	GO:0098722	3	0.048
regulation of cell activation	GO:0050865	289	0.048
cell growth	GO:0016049	130	0.047
positive regulation of rho gtpase activity	GO:0032321	41	0.047
cellular nitrogen compound catabolic process	GO:0044270	280	0.047	Mouse
positive regulation of ras gtpase activity	GO:0032320	65	0.046
regulation of actin filament based process	GO:0032970	99	0.046	Mouse
muscle cell differentiation	GO:0042692	261	0.046
response to peptide hormone	GO:0043434	127	0.046
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.045
nucleotide metabolic process	GO:0009117	332	0.045	Mouse
regulation of mitotic cell cycle	GO:0007346	126	0.045
positive regulation of cellular component biogenesis	GO:0044089	94	0.045	Mouse
pole plasm assembly	GO:0007315	2	0.045
peptide transport	GO:0015833	133	0.045	Mouse
notch signaling pathway	GO:0007219	71	0.044
positive regulation of nucleotide catabolic process	GO:0030813	88	0.044
regulation of epithelial cell proliferation	GO:0050678	141	0.044
regulation of canonical wnt signaling pathway	GO:0060828	82	0.044
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.043
nucleotide catabolic process	GO:0009166	217	0.042	Mouse
nuclear transport	GO:0051169	139	0.042
b cell activation	GO:0042113	161	0.042
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.042
response to insulin	GO:0032868	100	0.042
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.042
morphogenesis of embryonic epithelium	GO:0016331	159	0.042	Worm
regulation of cell size	GO:0008361	72	0.042
protein localization to organelle	GO:0033365	185	0.042
membrane organization	GO:0061024	245	0.042
positive regulation of protein phosphorylation	GO:0001934	242	0.042	Mouse
canonical wnt signaling pathway	GO:0060070	130	0.042
heterocycle catabolic process	GO:0046700	280	0.042	Mouse
germ cell development	GO:0007281	185	0.042	Worm
regulation of rho gtpase activity	GO:0032319	58	0.041	Mouse
regulation of gtp catabolic process	GO:0033124	113	0.041	Mouse
stem cell proliferation	GO:0072089	117	0.041
g protein coupled receptor signaling pathway	GO:0007186	243	0.041
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.041
t cell differentiation in thymus	GO:0033077	77	0.041
mesoderm development	GO:0007498	100	0.040	Mouse
response to growth factor	GO:0070848	198	0.040
organelle localization	GO:0051640	179	0.040
purine containing compound metabolic process	GO:0072521	311	0.040	Mouse
regulation of jun kinase activity	GO:0043506	40	0.040	Mouse
actin filament organization	GO:0007015	113	0.040	Mouse
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.040	Mouse
inflammatory response	GO:0006954	244	0.039
lymphocyte differentiation	GO:0030098	242	0.039
negative regulation of cellular component organization	GO:0051129	194	0.039	Mouse
oocyte construction	GO:0007308	2	0.039
positive regulation of proteolysis	GO:0045862	85	0.039
oocyte anterior posterior axis specification	GO:0007314	2	0.039
regulation of purine nucleotide catabolic process	GO:0033121	122	0.039	Mouse
response to organic cyclic compound	GO:0014070	198	0.039
regulation of purine nucleotide metabolic process	GO:1900542	169	0.039	Mouse
positive regulation of hydrolase activity	GO:0051345	148	0.039
cellular response to peptide hormone stimulus	GO:0071375	92	0.038
positive regulation of cellular catabolic process	GO:0031331	148	0.038
epithelial tube formation	GO:0072175	130	0.038
skeletal muscle organ development	GO:0060538	163	0.038
positive regulation of transferase activity	GO:0051347	167	0.038	Mouse
striated muscle tissue development	GO:0014706	293	0.037
amine metabolic process	GO:0009308	45	0.037
negative regulation of cell proliferation	GO:0008285	296	0.037
regulation of secretion by cell	GO:1903530	249	0.037	Mouse
embryonic epithelial tube formation	GO:0001838	130	0.037
positive regulation of apoptotic process	GO:0043065	217	0.037	Mouse
regulation of lymphocyte activation	GO:0051249	240	0.037
hormone secretion	GO:0046879	128	0.036
regulation of establishment of protein localization	GO:0070201	181	0.036
oxidation reduction process	GO:0055114	342	0.036
small molecule biosynthetic process	GO:0044283	132	0.036
negative regulation of cell growth	GO:0030308	44	0.036
angiogenesis	GO:0001525	201	0.036	Mouse
protein localization to plasma membrane	GO:0072659	57	0.035
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.035	Mouse
spermatogenesis	GO:0007283	284	0.035
regulation of cellular ketone metabolic process	GO:0010565	66	0.035
regulation of ras gtpase activity	GO:0032318	88	0.035	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.035
regulation of cell motility	GO:2000145	236	0.035	Mouse
positive regulation of cell activation	GO:0050867	158	0.035
macromolecule catabolic process	GO:0009057	281	0.034
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.034
negative regulation of hydrolase activity	GO:0051346	71	0.034
protein modification by small protein conjugation	GO:0032446	187	0.034
regulation of cellular catabolic process	GO:0031329	242	0.033	Mouse
urogenital system development	GO:0001655	261	0.033	Mouse
regulation of proteolysis	GO:0030162	164	0.033	Mouse
neural tube closure	GO:0001843	90	0.033
negative regulation of phosphate metabolic process	GO:0045936	184	0.033
determination of left right symmetry	GO:0007368	80	0.032
positive regulation of secretion by cell	GO:1903532	114	0.032
cellular amine metabolic process	GO:0044106	44	0.032
regulation of extent of cell growth	GO:0061387	52	0.032
lipid biosynthetic process	GO:0008610	179	0.032
negative regulation of cellular protein metabolic process	GO:0032269	247	0.032
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.032
inner ear morphogenesis	GO:0042472	101	0.031	Mouse
regulation of cell growth	GO:0001558	91	0.031
innate immune response	GO:0045087	157	0.031	Fly
sensory organ morphogenesis	GO:0090596	242	0.031	Mouse
organelle assembly	GO:0070925	177	0.031
ear development	GO:0043583	200	0.031	Mouse
positive regulation of gtp catabolic process	GO:0033126	85	0.031
cellular amino acid metabolic process	GO:0006520	103	0.031
regulation of establishment of planar polarity	GO:0090175	28	0.030
heart morphogenesis	GO:0003007	178	0.030	Mouse
fat cell differentiation	GO:0045444	160	0.030
regulation of endocytosis	GO:0030100	69	0.030
peptidyl tyrosine modification	GO:0018212	145	0.030	Mouse Worm
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.030
cell junction organization	GO:0034330	77	0.030
positive regulation of nucleotide metabolic process	GO:0045981	114	0.030
monosaccharide metabolic process	GO:0005996	106	0.030
regulation of cellular component biogenesis	GO:0044087	181	0.030	Mouse
cell division	GO:0051301	120	0.030
exocrine system development	GO:0035272	45	0.030
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.030
ossification	GO:0001503	216	0.030	Mouse
pallium development	GO:0021543	120	0.029	Mouse
leukocyte mediated immunity	GO:0002443	174	0.029
guanosine containing compound catabolic process	GO:1901069	144	0.029	Mouse
renal system development	GO:0072001	225	0.029
t cell differentiation	GO:0030217	174	0.029
mitotic cell cycle	GO:0000278	195	0.029
mesenchymal cell differentiation	GO:0048762	107	0.029	Mouse
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.029
somitogenesis	GO:0001756	69	0.029
dna metabolic process	GO:0006259	303	0.029
negative regulation of neuron differentiation	GO:0045665	101	0.029	Mouse
cytokine production	GO:0001816	319	0.029
cellular response to cytokine stimulus	GO:0071345	189	0.029
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.029
telencephalon development	GO:0021537	186	0.029	Mouse
regulation of ras protein signal transduction	GO:0046578	114	0.028	Mouse
synapse organization	GO:0050808	125	0.028	Mouse
regulation of peptidase activity	GO:0052547	96	0.028	Mouse
ameboidal type cell migration	GO:0001667	128	0.028	Mouse
limbic system development	GO:0021761	72	0.028	Mouse
regulation of asymmetric cell division	GO:0009786	4	0.028
t cell activation	GO:0042110	289	0.028
gastrulation	GO:0007369	116	0.028	Mouse
cell type specific apoptotic process	GO:0097285	268	0.027	Mouse
regulation of endopeptidase activity	GO:0052548	89	0.027	Mouse
cell substrate adhesion	GO:0031589	130	0.027
negative regulation of wnt signaling pathway	GO:0030178	73	0.027
regulation of organ morphogenesis	GO:2000027	144	0.027
positive regulation of growth	GO:0045927	104	0.027
protein catabolic process	GO:0030163	221	0.026
microtubule cytoskeleton organization	GO:0000226	157	0.026
regulation of cellular response to stress	GO:0080135	159	0.026	Mouse
hexose metabolic process	GO:0019318	98	0.026
limb development	GO:0060173	166	0.026
positive regulation of map kinase activity	GO:0043406	84	0.026	Mouse
regulation of nucleoside metabolic process	GO:0009118	130	0.026	Mouse
endomembrane system organization	GO:0010256	147	0.026
peptidyl amino acid modification	GO:0018193	336	0.026	Mouse Worm
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.025
endocytosis	GO:0006897	168	0.025
regulation of cytokine production	GO:0001817	266	0.025
protein polymerization	GO:0051258	57	0.025
hair follicle development	GO:0001942	85	0.025
protein targeting	GO:0006605	143	0.025
salivary gland morphogenesis	GO:0007435	33	0.025
apoptotic signaling pathway	GO:0097190	306	0.025
response to extracellular stimulus	GO:0009991	127	0.025
regulation of apoptotic signaling pathway	GO:2001233	197	0.024
protein localization to nucleus	GO:0034504	121	0.024
gonad development	GO:0008406	141	0.024
establishment or maintenance of cell polarity	GO:0007163	86	0.024	Mouse
positive regulation of nucleoside metabolic process	GO:0045979	91	0.024
organic hydroxy compound metabolic process	GO:1901615	203	0.024	Fly
peptide secretion	GO:0002790	114	0.024	Mouse
cell junction maintenance	GO:0034331	4	0.024
regulation of cellular component size	GO:0032535	121	0.024
regulation of homeostatic process	GO:0032844	182	0.024	Mouse
organic anion transport	GO:0015711	137	0.024
cardiac muscle tissue development	GO:0048738	130	0.023
positive regulation of cytoskeleton organization	GO:0051495	49	0.023	Mouse
production of molecular mediator of immune response	GO:0002440	103	0.023
phospholipid metabolic process	GO:0006644	87	0.023	Mouse
regulation of peptide transport	GO:0090087	91	0.023	Mouse
regulation of secretion	GO:0051046	274	0.023	Mouse
stress activated protein kinase signaling cascade	GO:0031098	81	0.023	Mouse
fasciculation of sensory neuron axon	GO:0097155	3	0.023	Mouse
regulation of cell cycle process	GO:0010564	160	0.023
lymphocyte mediated immunity	GO:0002449	139	0.023
female sex differentiation	GO:0046660	84	0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.023	Mouse
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.023
negative regulation of endopeptidase activity	GO:0010951	44	0.023
defense response to other organism	GO:0098542	197	0.022
metencephalon development	GO:0022037	89	0.022
intracellular protein transport	GO:0006886	204	0.022
cartilage development	GO:0051216	140	0.022
cellular response to amino acid stimulus	GO:0071230	29	0.022
glucose metabolic process	GO:0006006	92	0.022
steroid metabolic process	GO:0008202	119	0.022
respiratory tube development	GO:0030323	167	0.022
ear morphogenesis	GO:0042471	118	0.022	Mouse
negative regulation of synapse assembly	GO:0051964	3	0.022	Mouse
modification dependent macromolecule catabolic process	GO:0043632	133	0.022
protein kinase b signaling	GO:0043491	74	0.022
nuclear division	GO:0000280	158	0.022
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.022
monocarboxylic acid metabolic process	GO:0032787	191	0.022
ubiquitin dependent protein catabolic process	GO:0006511	129	0.022
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.022
primary neural tube formation	GO:0014020	95	0.022
positive regulation of jun kinase activity	GO:0043507	30	0.022	Mouse
mitotic cell cycle process	GO:1903047	159	0.021
meiotic nuclear division	GO:0007126	115	0.021
neuron projection extension	GO:1990138	64	0.021
branching morphogenesis of an epithelial tube	GO:0048754	159	0.021	Mouse
oogenesis	GO:0048477	56	0.021	Worm
interleukin 8 production	GO:0032637	4	0.021
vagus nerve development	GO:0021564	3	0.021
positive regulation of secretion	GO:0051047	130	0.021
peptidyl serine modification	GO:0018209	83	0.021
negative regulation of protein metabolic process	GO:0051248	282	0.021
regulation of hormone levels	GO:0010817	211	0.021
platelet activation	GO:0030168	40	0.021
glycerolipid metabolic process	GO:0046486	122	0.021	Mouse
male gamete generation	GO:0048232	285	0.020
chromatin modification	GO:0016568	187	0.020
regulation of lipid metabolic process	GO:0019216	118	0.020	Mouse
negative regulation of protein maturation	GO:1903318	79	0.020
sensory perception of sound	GO:0007605	97	0.020
antimicrobial peptide production	GO:0002775	2	0.020
leukocyte migration	GO:0050900	124	0.020
digestive tract morphogenesis	GO:0048546	147	0.020	Mouse
nucleocytoplasmic transport	GO:0006913	139	0.020
cellular response to lipid	GO:0071396	145	0.020
actin polymerization or depolymerization	GO:0008154	54	0.020
blood coagulation	GO:0007596	76	0.020
gtp metabolic process	GO:0046039	144	0.020	Mouse
muscle cell development	GO:0055001	133	0.020
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.020
protein secretion	GO:0009306	111	0.020
lung development	GO:0030324	164	0.020
regulation of protein processing	GO:0070613	96	0.020
limb morphogenesis	GO:0035108	149	0.020
cell chemotaxis	GO:0060326	81	0.019	Mouse
multicellular organismal homeostasis	GO:0048871	164	0.019
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.019
male sex differentiation	GO:0046661	109	0.019
regulation of protein catabolic process	GO:0042176	108	0.019
inorganic ion transmembrane transport	GO:0098660	234	0.019
antimicrobial peptide biosynthetic process	GO:0002777	2	0.019
stem cell development	GO:0048864	219	0.019	Mouse
maintenance of cell number	GO:0098727	3	0.019
hippocampus development	GO:0021766	52	0.019	Mouse
guanosine containing compound metabolic process	GO:1901068	144	0.019	Mouse
multicellular organism growth	GO:0035264	161	0.019
cellular amide metabolic process	GO:0043603	58	0.019
negative regulation of proteolysis	GO:0045861	74	0.019
locomotory behavior	GO:0007626	195	0.019	Mouse
reactive oxygen species metabolic process	GO:0072593	84	0.019
syncytium formation	GO:0006949	43	0.019
response to inorganic substance	GO:0010035	96	0.019
engulfment of apoptotic cell	GO:0043652	3	0.019
regulation of membrane potential	GO:0042391	192	0.019
negative regulation of peptidase activity	GO:0010466	46	0.019
nuclear import	GO:0051170	95	0.019
defecation	GO:0030421	1	0.019
insulin receptor signaling pathway	GO:0008286	49	0.018
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.018
myoblast differentiation	GO:0045445	52	0.018
olfactory bulb development	GO:0021772	30	0.018
myotube differentiation	GO:0014902	105	0.018
protein localization to membrane	GO:0072657	108	0.018
neuroblast proliferation	GO:0007405	49	0.018
blood circulation	GO:0008015	195	0.018
positive regulation of immune effector process	GO:0002699	107	0.018
positive regulation of cell cycle	GO:0045787	92	0.018
cellular homeostasis	GO:0019725	240	0.018	Mouse
mammary gland epithelium development	GO:0061180	65	0.018	Mouse
appendage development	GO:0048736	166	0.018
regulation of protein maturation	GO:1903317	96	0.018
regulation of epithelial cell migration	GO:0010632	35	0.018	Mouse
actin filament polymerization	GO:0030041	44	0.018
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.018
organelle fission	GO:0048285	170	0.018
cerebellar granule cell precursor tangential migration	GO:0021935	1	0.018
regulation of notch signaling pathway	GO:0008593	35	0.018
compound eye development	GO:0048749	1	0.018
alpha beta t cell differentiation	GO:0046632	69	0.018
myeloid leukocyte migration	GO:0097529	57	0.018
positive regulation of cell adhesion	GO:0045785	80	0.018
response to oxidative stress	GO:0006979	123	0.018
extrinsic apoptotic signaling pathway	GO:0097191	126	0.018
positive regulation of epithelial cell proliferation	GO:0050679	68	0.018
organonitrogen compound biosynthetic process	GO:1901566	192	0.018
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.018
regulation of lymphocyte proliferation	GO:0050670	117	0.018
rap protein signal transduction	GO:0032486	3	0.018
digestive system development	GO:0055123	200	0.018	Mouse
positive regulation of lymphocyte activation	GO:0051251	140	0.018
defense response to bacterium	GO:0042742	119	0.018
mesodermal cell migration	GO:0008078	4	0.018
cellular protein complex assembly	GO:0043623	116	0.018
cellular response to acid chemical	GO:0071229	68	0.017
cell cell junction organization	GO:0045216	72	0.017
olfactory bulb axon guidance	GO:0071678	1	0.017
positive regulation of cell migration	GO:0030335	109	0.017
reactive oxygen species biosynthetic process	GO:1903409	8	0.017
muscle fiber development	GO:0048747	76	0.017
morphogenesis of a polarized epithelium	GO:0001738	37	0.017
modification dependent protein catabolic process	GO:0019941	133	0.017
cell fate commitment	GO:0045165	210	0.017
sensory perception	GO:0007600	245	0.017	Mouse
adult locomotory behavior	GO:0008344	91	0.017	Mouse
intracellular mrna localization	GO:0008298	4	0.017
cation transport	GO:0006812	399	0.017
placenta development	GO:0001890	140	0.017
embryonic skeletal system development	GO:0048706	120	0.017
embryonic appendage morphogenesis	GO:0035113	126	0.017
negative regulation of phosphorylation	GO:0042326	166	0.017
positive regulation of neuron projection development	GO:0010976	79	0.017
jnk cascade	GO:0007254	72	0.017	Mouse
inorganic cation transmembrane transport	GO:0098662	207	0.017
epithelial cell migration	GO:0010631	63	0.017	Mouse
mechanoreceptor differentiation	GO:0042490	67	0.017
lipid localization	GO:0010876	126	0.017
protein import	GO:0017038	101	0.017
adaptive immune response	GO:0002250	155	0.017
response to transforming growth factor beta	GO:0071559	88	0.017
myoblast differentiation involved in skeletal muscle regeneration	GO:0014835	3	0.017
response to steroid hormone	GO:0048545	56	0.017
chondrocyte differentiation	GO:0002062	72	0.016
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.016
negative regulation of protein processing	GO:0010955	79	0.016
establishment of organelle localization	GO:0051656	122	0.016
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.016
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.016	Mouse
regulation of t cell activation	GO:0050863	170	0.016
positive regulation of organelle organization	GO:0010638	128	0.016	Mouse
myotube cell development	GO:0014904	60	0.016
respiratory system development	GO:0060541	190	0.016
regulation of neural precursor cell proliferation	GO:2000177	70	0.016
myeloid cell differentiation	GO:0030099	233	0.016	Mouse
negative regulation of protein modification process	GO:0031400	163	0.016
developmental cell growth	GO:0048588	84	0.016

Ephb6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.019
disease of anatomical entity	DOID:7	0.019
neuropathy	DOID:870	0.018
neuromuscular disease	DOID:440	0.018

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