IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Ctps

cytidine 5'-triphosphate synthase

Ensembl: ENSMUSG00000028633
Entrez: 51797
UniProtKB: P70698

Process Predictions
Disease Predictions

Ctps biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular response to dna damage stimulus	GO:0006974	207	0.208
dna metabolic process	GO:0006259	303	0.162
protein modification by small protein conjugation or removal	GO:0070647	207	0.156
dna dealkylation	GO:0035510	11	0.150
organophosphate biosynthetic process	GO:0090407	122	0.143	Human
nucleoside phosphate metabolic process	GO:0006753	338	0.138	Human
nls bearing protein import into nucleus	GO:0006607	2	0.121
polyamine biosynthetic process	GO:0006596	2	0.111
regulation of protein localization	GO:0032880	231	0.104
dna repair	GO:0006281	107	0.103
organelle fission	GO:0048285	170	0.081
nuclear division	GO:0000280	158	0.081
protein desumoylation	GO:0016926	2	0.078
amine metabolic process	GO:0009308	45	0.077
cytoplasmic transport	GO:0016482	234	0.073
cellular amine metabolic process	GO:0044106	44	0.071
nucleotide biosynthetic process	GO:0009165	78	0.070	Human
response to amino acid	GO:0043200	37	0.068
cellular amino acid metabolic process	GO:0006520	103	0.063
ossification	GO:0001503	216	0.063
transmembrane transport	GO:0055085	412	0.062
mrna transport	GO:0051028	13	0.061
negative regulation of molecular function	GO:0044092	258	0.061
nucleotide metabolic process	GO:0009117	332	0.060	Human
regulation of intracellular transport	GO:0032386	159	0.054
regulation of cell cycle	GO:0051726	281	0.050
cellular response to amino acid stimulus	GO:0071230	29	0.049
organonitrogen compound biosynthetic process	GO:1901566	192	0.048	Human
cellular response to acid chemical	GO:0071229	68	0.048
regulation of establishment of protein localization	GO:0070201	181	0.047
regulation of hydrolase activity	GO:0051336	246	0.047
purine nucleotide metabolic process	GO:0006163	302	0.047
nitrogen compound transport	GO:0071705	271	0.046
positive regulation of apoptotic process	GO:0043065	217	0.045
regulation of cytoplasmic transport	GO:1903649	112	0.045
response to acid chemical	GO:0001101	111	0.042
microtubule cytoskeleton organization	GO:0000226	157	0.042
nucleoside metabolic process	GO:0009116	246	0.041	Human
negative regulation of phosphate metabolic process	GO:0045936	184	0.040
cellular homeostasis	GO:0019725	240	0.040
nucleoside phosphate catabolic process	GO:1901292	222	0.037
negative regulation of phosphorylation	GO:0042326	166	0.036
positive regulation of protein transport	GO:0051222	93	0.036
negative regulation of protein metabolic process	GO:0051248	282	0.035
cellular protein catabolic process	GO:0044257	155	0.035
regulation of intracellular protein transport	GO:0033157	82	0.034
positive regulation of transcription from rna polymerase i promoter	GO:0045943	3	0.034
positive regulation of programmed cell death	GO:0043068	218	0.034
urogenital system development	GO:0001655	261	0.034
ribose phosphate metabolic process	GO:0019693	291	0.033	Human
ion transmembrane transport	GO:0034220	361	0.033
nucleobase containing small molecule metabolic process	GO:0055086	352	0.033	Human
folic acid containing compound metabolic process	GO:0006760	3	0.032
atp metabolic process	GO:0046034	75	0.032
protein import into nucleus	GO:0006606	95	0.032
ribonucleotide metabolic process	GO:0009259	291	0.031	Human
regulation of protein binding	GO:0043393	60	0.031
nucleoside triphosphate metabolic process	GO:0009141	230	0.031	Human
mapk cascade	GO:0000165	281	0.031
regulation of protein transport	GO:0051223	163	0.031
protein targeting	GO:0006605	143	0.030
positive regulation of cell death	GO:0010942	224	0.030
response to light stimulus	GO:0009416	135	0.029
regulation of protein catabolic process	GO:0042176	108	0.029
cellular biogenic amine metabolic process	GO:0006576	28	0.029
response to organonitrogen compound	GO:0010243	246	0.029
macromolecule catabolic process	GO:0009057	281	0.028
methylation	GO:0032259	134	0.028
nuclear export	GO:0051168	34	0.028
cation transport	GO:0006812	399	0.028
protein import	GO:0017038	101	0.028
carbohydrate derivative biosynthetic process	GO:1901137	183	0.027	Human
glycosyl compound metabolic process	GO:1901657	246	0.027	Human
oxidation reduction process	GO:0055114	342	0.027
organic anion transport	GO:0015711	137	0.027
negative regulation of protein phosphorylation	GO:0001933	126	0.027
protein localization to nucleus	GO:0034504	121	0.026
establishment of rna localization	GO:0051236	18	0.026
dna modification	GO:0006304	50	0.026
carbohydrate derivative catabolic process	GO:1901136	231	0.026
cellular nitrogen compound catabolic process	GO:0044270	280	0.026
mitotic nuclear division	GO:0007067	48	0.026
purine nucleoside metabolic process	GO:0042278	241	0.026
anion transport	GO:0006820	177	0.026
divalent metal ion transport	GO:0070838	172	0.025
purine ribonucleotide metabolic process	GO:0009150	290	0.025
cellular response to cytokine stimulus	GO:0071345	189	0.024
nucleocytoplasmic transport	GO:0006913	139	0.024
multicellular organismal homeostasis	GO:0048871	164	0.024
negative regulation of cell proliferation	GO:0008285	296	0.024
regulation of organelle organization	GO:0033043	289	0.024
apoptotic signaling pathway	GO:0097190	306	0.024
intrinsic apoptotic signaling pathway	GO:0097193	132	0.024
hematopoietic progenitor cell differentiation	GO:0002244	143	0.024
ribonucleoside catabolic process	GO:0042454	206	0.023
ribose phosphate biosynthetic process	GO:0046390	59	0.023	Human
alpha amino acid metabolic process	GO:1901605	59	0.023
cellular macromolecule catabolic process	GO:0044265	206	0.023
actin cytoskeleton organization	GO:0030036	220	0.023
purine ribonucleoside catabolic process	GO:0046130	205	0.023
metaphase plate congression	GO:0051310	2	0.022
regulation of nucleocytoplasmic transport	GO:0046822	73	0.022
transcription coupled nucleotide excision repair	GO:0006283	2	0.022
regulation of protein import into nucleus	GO:0042306	52	0.022
negative regulation of phosphorus metabolic process	GO:0010563	184	0.021
regulation of cellular amino acid metabolic process	GO:0006521	5	0.021
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.021	Human
response to organic cyclic compound	GO:0014070	198	0.021
receptor mediated endocytosis	GO:0006898	51	0.021
intracellular protein transport	GO:0006886	204	0.021
tissue homeostasis	GO:0001894	115	0.020
purine ribonucleoside metabolic process	GO:0046128	241	0.020
dephosphorylation	GO:0016311	129	0.020
negative regulation of cellular protein metabolic process	GO:0032269	247	0.020
forebrain development	GO:0030900	302	0.020
regulation of kinase activity	GO:0043549	249	0.020
oocyte construction	GO:0007308	2	0.020
regulation of cellular amine metabolic process	GO:0033238	20	0.020
cellular response to organonitrogen compound	GO:0071417	145	0.019
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.019
regulation of rna stability	GO:0043487	26	0.019
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.019
protein modification by small protein conjugation	GO:0032446	187	0.019
methionine transport	GO:0015821	1	0.019
protein catabolic process	GO:0030163	221	0.018
maturation of ssu rrna	GO:0030490	1	0.018
coenzyme metabolic process	GO:0006732	52	0.018
regulation of apoptotic signaling pathway	GO:2001233	197	0.018
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.018
regulation of cell division	GO:0051302	76	0.017
anion transmembrane transport	GO:0098656	71	0.017
positive regulation of intracellular protein transport	GO:0090316	42	0.017
kidney development	GO:0001822	213	0.017
organic hydroxy compound metabolic process	GO:1901615	203	0.017
signal transduction by p53 class mediator	GO:0072331	51	0.017
purine nucleoside catabolic process	GO:0006152	205	0.016
membrane organization	GO:0061024	245	0.016
regulation of mrna stability	GO:0043488	23	0.016
translation	GO:0006412	93	0.016
developmental growth involved in morphogenesis	GO:0060560	138	0.016
regulation of circadian rhythm	GO:0042752	58	0.016
ncrna processing	GO:0034470	26	0.016
macromolecule methylation	GO:0043414	120	0.016
cellular ketone metabolic process	GO:0042180	84	0.016
meiotic cell cycle	GO:0051321	122	0.015
nucleotide catabolic process	GO:0009166	217	0.015
negative regulation of protein modification process	GO:0031400	163	0.015
blood circulation	GO:0008015	195	0.015
negative regulation of cell development	GO:0010721	169	0.015
demethylation	GO:0070988	23	0.015
carboxylic acid transport	GO:0046942	100	0.015
transcription from rna polymerase i promoter	GO:0006360	13	0.015
cellular response to interleukin 4	GO:0071353	21	0.015
protein localization to organelle	GO:0033365	185	0.015
neuron death	GO:0070997	154	0.015
stem cell differentiation	GO:0048863	268	0.015
aromatic compound catabolic process	GO:0019439	286	0.015
purine containing compound biosynthetic process	GO:0072522	70	0.015
regulation of proteolysis	GO:0030162	164	0.015
cell growth	GO:0016049	130	0.015
respiratory system development	GO:0060541	190	0.014
male gamete generation	GO:0048232	285	0.014
regulation of cellular ketone metabolic process	GO:0010565	66	0.014
anatomical structure homeostasis	GO:0060249	145	0.014
posttranscriptional regulation of gene expression	GO:0010608	155	0.014
cell adhesion	GO:0007155	329	0.014
axonogenesis	GO:0007409	274	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
heart morphogenesis	GO:0003007	178	0.014
response to oxidative stress	GO:0006979	123	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.014
maintenance of location	GO:0051235	89	0.014
response to extracellular stimulus	GO:0009991	127	0.014
response to nutrient levels	GO:0031667	109	0.014
response to radiation	GO:0009314	165	0.014
cellular response to lipid	GO:0071396	145	0.014
endocytosis	GO:0006897	168	0.014
positive regulation of intracellular transport	GO:0032388	70	0.014
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.014
heart contraction	GO:0060047	93	0.013
regulation of hormone levels	GO:0010817	211	0.013
regulation of body fluid levels	GO:0050878	162	0.013
organic cyclic compound catabolic process	GO:1901361	295	0.013
organic acid transport	GO:0015849	101	0.013
neuron apoptotic process	GO:0051402	142	0.013
organophosphate catabolic process	GO:0046434	232	0.013
regulation of binding	GO:0051098	111	0.013
regulation of transmembrane transport	GO:0034762	128	0.013
small gtpase mediated signal transduction	GO:0007264	97	0.013
glycosyl compound catabolic process	GO:1901658	206	0.013
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
i kappab kinase nf kappab signaling	GO:0007249	85	0.013
cell type specific apoptotic process	GO:0097285	268	0.013
establishment of protein localization to organelle	GO:0072594	118	0.012
small molecule biosynthetic process	GO:0044283	132	0.012
nucleoside catabolic process	GO:0009164	206	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
purine ribonucleotide catabolic process	GO:0009154	208	0.012
cell maturation	GO:0048469	127	0.012
reactive nitrogen species metabolic process	GO:2001057	0	0.012
sensory perception	GO:0007600	245	0.012
muscle tissue development	GO:0060537	308	0.012
divalent inorganic cation homeostasis	GO:0072507	138	0.012
regulation of cell cycle process	GO:0010564	160	0.012
ras protein signal transduction	GO:0007265	77	0.012
locomotory behavior	GO:0007626	195	0.012
regulation of cellular response to stress	GO:0080135	159	0.012
renal system development	GO:0072001	225	0.012
regulation of ion transport	GO:0043269	215	0.012
protein alkylation	GO:0008213	81	0.012
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.012
mitotic cell cycle process	GO:1903047	159	0.012
single organism nuclear import	GO:1902593	95	0.012
spermatogenesis	GO:0007283	284	0.011
nucleoside monophosphate metabolic process	GO:0009123	85	0.011
sequestering of calcium ion	GO:0051208	18	0.011
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.011
regulation of cell projection organization	GO:0031344	206	0.011
regulation of neuron projection development	GO:0010975	169	0.011
positive regulation of cellular amine metabolic process	GO:0033240	5	0.011
regulation of cytoskeleton organization	GO:0051493	122	0.011
ribonucleotide catabolic process	GO:0009261	208	0.011
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.011
cofactor metabolic process	GO:0051186	80	0.011
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	57	0.011
epithelial cell proliferation	GO:0050673	174	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
microtubule based process	GO:0007017	236	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
nuclear import	GO:0051170	95	0.011
regulation of homeostatic process	GO:0032844	182	0.011
regulation of cellular component size	GO:0032535	121	0.011
regulation of neuron death	GO:1901214	134	0.011
heart trabecula formation	GO:0060347	14	0.011
mitotic cell cycle	GO:0000278	195	0.011
response to uv	GO:0009411	44	0.011
ribonucleoside metabolic process	GO:0009119	245	0.011	Human
development of primary sexual characteristics	GO:0045137	143	0.011
positive regulation of organelle organization	GO:0010638	128	0.011
mrna metabolic process	GO:0016071	84	0.011
regulation of peptidase activity	GO:0052547	96	0.011
branched chain amino acid transport	GO:0015803	2	0.011
regulation of neuron differentiation	GO:0045664	281	0.011
mrna export from nucleus	GO:0006406	11	0.011
engulfment of apoptotic cell	GO:0043652	3	0.011
actin filament organization	GO:0007015	113	0.011
positive regulation of cytoskeleton organization	GO:0051495	49	0.011
regulation of mapk cascade	GO:0043408	248	0.010
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.010
negative regulation of neuron death	GO:1901215	98	0.010
response to inorganic substance	GO:0010035	96	0.010
glucose homeostasis	GO:0042593	128	0.010
gland development	GO:0048732	330	0.010
polyamine metabolic process	GO:0006595	5	0.010
carbohydrate homeostasis	GO:0033500	128	0.010
protein ubiquitination	GO:0016567	171	0.010
leukocyte proliferation	GO:0070661	172	0.010	Human
atp catabolic process	GO:0006200	55	0.010
mesenchymal cell differentiation	GO:0048762	107	0.010
cation transmembrane transport	GO:0098655	266	0.010
regulation of map kinase activity	GO:0043405	120	0.010
regulation of protein serine threonine kinase activity	GO:0071900	157	0.010
circulatory system process	GO:0003013	197	0.010

Ctps disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.059
nervous system disease	DOID:863	0.059
large intestine cancer	DOID:5672	0.051
colon cancer	DOID:219	0.051
intestinal cancer	DOID:10155	0.051
gastrointestinal system cancer	DOID:3119	0.051
cancer	DOID:162	0.051
disease of cellular proliferation	DOID:14566	0.051
organ system cancer	DOID:0050686	0.051
colorectal cancer	DOID:9256	0.051
neurodegenerative disease	DOID:1289	0.047
central nervous system disease	DOID:331	0.047
neuromuscular disease	DOID:440	0.043
neuropathy	DOID:870	0.043
motor neuron disease	DOID:231	0.010

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