Mus musculus

91 known processes

Ube2i

ubiquitin-conjugating enzyme E2I

(Aliases: F830028O17Rik,Ubce2i,Ubce9,5830467E05Rik,UBC9)

Ube2i biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
stem cell maintenanceGO:00198271300.125
germ cell developmentGO:00072811850.115
rna splicingGO:0008380540.112
mrna metabolic processGO:0016071840.111
t cell activationGO:00421102890.108
male gamete generationGO:00482322850.106
leukocyte differentiationGO:00025213420.105
rna processingGO:00063961050.105
regulation of cell activationGO:00508652890.103
protein modification by small protein conjugation or removalGO:00706472070.101
Human Zebrafish Rat Worm Fly
stem cell differentiationGO:00488632680.096
cell fate commitmentGO:00451652100.093
lymphocyte differentiationGO:00300982420.087
regulation of lymphocyte activationGO:00512492400.081
regulation of bindingGO:00510981110.077
regulation of cellular ketone metabolic processGO:0010565660.075
heterocycle catabolic processGO:00467002800.074
spermatogenesisGO:00072832840.071
regulation of synaptic growth at neuromuscular junctionGO:000858240.068
cellular response to dna damage stimulusGO:00069742070.067
Fly
negative regulation of cellular amine metabolic processGO:003323910.064
regulation of cellular component biogenesisGO:00440871810.061
camera type eye developmentGO:00430102660.060
t cell differentiationGO:00302171740.058
regulation of multi organism processGO:00439001110.055
stem cell fate specificationGO:004886630.055
cellular amine metabolic processGO:0044106440.054
rna splicing via transesterification reactionsGO:0000375430.054
purine containing compound metabolic processGO:00725213110.052
negative regulation of molecular functionGO:00440922580.051
regulation of leukocyte differentiationGO:19021051590.051
fat cell differentiationGO:00454441600.051
regulation of membrane potentialGO:00423911920.050
positive regulation of cell activationGO:00508671580.050
synapse organizationGO:00508081250.049
membrane organizationGO:00610242450.049
myeloid cell differentiationGO:00300992330.049
regulation of neuron differentiationGO:00456642810.048
formation of organ boundaryGO:001016010.046
synaptic transmissionGO:00072683290.046
renal system developmentGO:00720012250.046
intracellular protein transportGO:00068862040.046
Fly
leukocyte proliferationGO:00706611720.045
nucleotide metabolic processGO:00091173320.045
synapse assemblyGO:0007416560.045
histone modificationGO:00165701590.045
meiotic nuclear divisionGO:00071261150.044
Fly
protein localization to organelleGO:00333651850.044
Fly
mrna processingGO:0006397630.044
regionalizationGO:00030023370.043
Worm Fly
regulation of leukocyte proliferationGO:00706631210.043
organic cyclic compound catabolic processGO:19013612950.041
locomotory behaviorGO:00076261950.041
chromatin modificationGO:00165681870.040
nucleocytoplasmic transportGO:00069131390.039
Fly
purine nucleoside triphosphate metabolic processGO:00091442260.039
amine metabolic processGO:0009308450.039
negative regulation of protein modification processGO:00314001630.038
positive regulation of bindingGO:0051099490.038
somatic stem cell maintenanceGO:0035019470.038
t cell differentiation in thymusGO:0033077770.038
multicellular organism growthGO:00352641610.038
posttranscriptional regulation of gene expressionGO:00106081550.037
negative regulation of protein metabolic processGO:00512482820.036
negative regulation of cellular protein metabolic processGO:00322692470.036
action potentialGO:0001508780.035
skeletal system developmentGO:00015013560.035
neuroblast differentiationGO:001401620.035
regulation of cellular amine metabolic processGO:0033238200.034
rhythmic processGO:00485111740.034
dna repairGO:00062811070.034
wnt signaling pathwayGO:00160551880.034
purine ribonucleoside metabolic processGO:00461282410.033
neuronal action potentialGO:0019228540.032
protein modification by small protein conjugationGO:00324461870.032
Human Zebrafish Rat Worm Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.032
circadian rhythmGO:00076231140.032
cellular amino acid metabolic processGO:00065201030.032
multicellular organismal signalingGO:0035637910.032
negative regulation of cell proliferationGO:00082852960.032
Fly
positive regulation of protein modification processGO:00314012990.032
mrna splicing via spliceosomeGO:0000398430.031
development of primary sexual characteristicsGO:00451371430.031
Worm
regulation of protein complex assemblyGO:0043254830.031
methylationGO:00322591340.031
nucleoside triphosphate catabolic processGO:00091432050.031
organonitrogen compound catabolic processGO:19015652640.031
positive regulation of cell developmentGO:00107202370.030
aromatic compound catabolic processGO:00194392860.030
digestive tract developmentGO:00485651900.030
Worm
gonad developmentGO:00084061410.030
Worm
spermatid differentiationGO:00485151150.030
transmission of nerve impulseGO:0019226760.030
regulation of mrna processingGO:0050684410.029
nucleoside metabolic processGO:00091162460.029
kidney developmentGO:00018222130.029
regulation of myeloid leukocyte differentiationGO:0002761580.029
learning or memoryGO:00076111480.029
chemotaxisGO:00069352470.028
protein localization to nucleusGO:00345041210.028
Fly
myeloid cell homeostasisGO:00022621140.028
positive regulation of cellular component biogenesisGO:0044089940.028
nucleoside phosphate metabolic processGO:00067533380.028
lymphocyte proliferationGO:00466511640.028
stem cell developmentGO:00488642190.027
glial cell differentiationGO:00100011310.027
cognitionGO:00508901490.027
regulation of protein localizationGO:00328802310.027
Worm
positive regulation of apoptotic processGO:00430652170.027
spermatid developmentGO:00072861080.027
developmental maturationGO:00217001930.026
regulation of sequence specific dna binding transcription factor activityGO:00510901060.026
Rat
organophosphate catabolic processGO:00464342320.026
regulation of ossificationGO:00302781120.026
ribonucleotide catabolic processGO:00092612080.026
negative regulation of phosphorylationGO:00423261660.026
axon ensheathmentGO:0008366760.026
mitotic cell cycle processGO:19030471590.026
Zebrafish Fly
epithelial cell developmentGO:00020641590.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.025
innate immune responseGO:00450871570.025
adaptive immune responseGO:00022501550.025
mitotic cell cycleGO:00002781950.025
Zebrafish Fly
rna interferenceGO:001624620.025
ribonucleoside triphosphate catabolic processGO:00092031990.025
telencephalon developmentGO:00215371860.025
connective tissue developmentGO:00614481790.025
nucleotide catabolic processGO:00091662170.025
regulation of lymphocyte proliferationGO:00506701170.025
protein import into nucleusGO:0006606950.024
Fly
positive regulation of programmed cell deathGO:00430682180.024
regulation of t cell activationGO:00508631700.024
gonad morphogenesisGO:003526210.024
ensheathment of neuronsGO:0007272760.024
epithelial tube morphogenesisGO:00605623030.024
negative regulation of cellular amino acid metabolic processGO:004576300.024
dna metabolic processGO:00062593030.024
urogenital system developmentGO:00016552610.024
respiratory system developmentGO:00605411900.024
nucleoside phosphate catabolic processGO:19012922220.024
carbohydrate derivative catabolic processGO:19011362310.024
negative regulation of immune system processGO:00026832090.024
Fly
ribonucleotide metabolic processGO:00092592910.024
cellular ketone metabolic processGO:0042180840.024
synapse assembly involved in innervationGO:006038610.024
ossificationGO:00015032160.024
positive regulation of lymphocyte activationGO:00512511400.023
peptidyl amino acid modificationGO:00181933360.023
purine nucleoside metabolic processGO:00422782410.023
myeloid leukocyte differentiationGO:00025731190.023
regulation of cellular amino acid metabolic processGO:000652150.023
meiotic cell cycle processGO:1903046770.023
Fly
positive regulation of neuron differentiationGO:00456661410.023
purine containing compound catabolic processGO:00725232130.022
organelle fissionGO:00482851700.022
Zebrafish Fly
glycosyl compound metabolic processGO:19016572460.022
cellular response to cytokine stimulusGO:00713451890.022
gland developmentGO:00487323300.022
Fly
regulation of wnt signaling pathwayGO:00301111230.022
regulation of cell cycleGO:00517262810.022
Zebrafish Fly
peptidyl lysine modificationGO:0018205770.022
macromolecule catabolic processGO:00090572810.022
Rat
negative regulation of intracellular signal transductionGO:19025321670.021
negative regulation of phosphorus metabolic processGO:00105631840.021
fertilizationGO:00095661270.021
negative regulation of phosphate metabolic processGO:00459361840.021
response to molecule of bacterial originGO:00022371430.021
positive regulation of nervous system developmentGO:00519622210.021
ribonucleoside catabolic processGO:00424542060.021
regulation of protein stabilityGO:0031647520.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
protein maturationGO:00516041760.021
symbiosis encompassing mutualism through parasitismGO:0044403830.021
circadian regulation of gene expressionGO:0032922480.021
purine ribonucleotide metabolic processGO:00091502900.021
immune effector processGO:00022523210.020
cytokine productionGO:00018163190.020
neuron projection guidanceGO:00974851410.020
cell fate determination involved in pattern specificationGO:006058210.020
gliogenesisGO:00420631410.020
cell type specific apoptotic processGO:00972852680.020
regulation of cell projection organizationGO:00313442060.019
positive regulation of organelle organizationGO:00106381280.019
positive regulation of cell deathGO:00109422240.019
regulation of proteolysisGO:00301621640.019
cell growthGO:00160491300.019
negative regulation of osteoblast differentiationGO:0045668300.019
heart morphogenesisGO:00030071780.019
cellular response to lipidGO:00713961450.019
positive regulation of cellular amine metabolic processGO:003324050.019
axonogenesisGO:00074092740.019
cellular response to external stimulusGO:0071496880.019
purine ribonucleoside catabolic processGO:00461302050.019
purine nucleotide metabolic processGO:00061633020.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
blood vessel morphogenesisGO:00485142850.019
response to organonitrogen compoundGO:00102432460.019
negative regulation of cell developmentGO:00107211690.019
protein acylationGO:0043543640.019
single fertilizationGO:0007338820.019
columnar cuboidal epithelial cell differentiationGO:0002065820.018
glucose homeostasisGO:00425931280.018
regulation of establishment of protein localizationGO:00702011810.018
regulation of nucleotide metabolic processGO:00061401690.018
regulation of neuron deathGO:19012141340.018
cell maturationGO:00484691270.018
regulation of organelle organizationGO:00330432890.018
Zebrafish
regulation of cytokine productionGO:00018172660.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
regulation of organ morphogenesisGO:20000271440.018
regulation of cellular catabolic processGO:00313292420.018
positive regulation of defense responseGO:00313491240.018
leukocyte mediated immunityGO:00024431740.018
regulation of protein kinase activityGO:00458592320.018
positive regulation of leukocyte differentiationGO:1902107860.018
sensory organ boundary specificationGO:000805210.018
lateral inhibitionGO:004633110.017
cytoplasmic transportGO:00164822340.017
Fly
response to radiationGO:00093141650.017
neuroepithelial cell differentiationGO:0060563370.017
ribonucleoside metabolic processGO:00091192450.017
purine nucleotide catabolic processGO:00061952110.017
response to lipopolysaccharideGO:00324961280.017
ribose phosphate metabolic processGO:00196932910.017
ribonucleoprotein complex subunit organizationGO:0071826280.017
regulation of intracellular transportGO:00323861590.017
regulation of defense responseGO:00313472330.017
negative regulation of multi organism processGO:0043901680.017
trna wobble base modificationGO:000209720.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
Rat
histone h4 acetylationGO:0043967100.017
gtp metabolic processGO:00460391440.017
response to acid chemicalGO:00011011110.017
regulation of epithelial cell proliferationGO:00506781410.017
macromolecule methylationGO:00434141200.017
nuclear divisionGO:00002801580.017
Zebrafish Fly
cell cycle arrestGO:0007050370.017
meiosis iGO:0007127600.017
transmembrane transportGO:00550854120.017
hematopoietic progenitor cell differentiationGO:00022441430.016
muscle cell differentiationGO:00426922610.016
positive regulation of hydrolase activityGO:00513451480.016
positive regulation of dna templated transcription elongationGO:003278620.016
nucleobase containing small molecule metabolic processGO:00550863520.016
protein methylationGO:0006479810.016
neuron deathGO:00709971540.016
divalent metal ion transportGO:00708381720.016
cellular nitrogen compound catabolic processGO:00442702800.016
regulation of purine nucleotide metabolic processGO:19005421690.016
molting cycleGO:0042303900.016
cellular protein catabolic processGO:00442571550.016
Rat
maintenance of locationGO:0051235890.016
multi multicellular organism processGO:00447061090.016
Worm
chromatin organizationGO:00063252060.016
cell adhesionGO:00071553290.016
nuclear transportGO:00511691390.016
Fly
cardiac muscle tissue developmentGO:00487381300.016
regulation of system processGO:00440572000.016
lipid localizationGO:00108761260.016
trna wobble uridine modificationGO:000209820.016
regulation of mapk cascadeGO:00434082480.016
erythrocyte differentiationGO:0030218880.015
carbohydrate homeostasisGO:00335001280.015
negative regulation of synapse assemblyGO:005196430.015
single organism nuclear importGO:1902593950.015
Fly
nucleoside catabolic processGO:00091642060.015
positive regulation of myeloid cell differentiationGO:0045639430.015
striated muscle tissue developmentGO:00147062930.015
neuromuscular processGO:0050905990.015
interspecies interaction between organismsGO:0044419830.015
pole plasm assemblyGO:000731520.015
muscle tissue developmentGO:00605373080.015
purine ribonucleotide catabolic processGO:00091542080.015
positive regulation of t cell activationGO:00508701010.015
organ growthGO:00352651170.015
positive regulation of proteolysisGO:0045862850.015
cell divisionGO:00513011200.015
Zebrafish
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.015
production of molecular mediator of immune responseGO:00024401030.015
forebrain developmentGO:00309003020.015
negative regulation of cellular component organizationGO:00511291940.015
negative regulation of protein phosphorylationGO:00019331260.015
t cell proliferationGO:00420981200.015
negative regulation of defense responseGO:0031348770.015
protein importGO:00170381010.015
Fly
nucleoside triphosphate metabolic processGO:00091412300.014
negative regulation of lymphocyte activationGO:0051250910.014
regulation of mrna metabolic processGO:1903311430.014
jak stat cascadeGO:0007259420.014
adult behaviorGO:00305341350.014
negative regulation of cytokine productionGO:0001818840.014
endocytosisGO:00068971680.014
cellular homeostasisGO:00197252400.014
negative regulation of cell activationGO:00508661110.014
regulation of neuron apoptotic processGO:00435231220.014
cd4 positive alpha beta t cell differentiationGO:0043367410.014
positive regulation of growthGO:00459271040.014
protein targetingGO:00066051430.014
Fly
b cell activationGO:00421131610.014
protein alkylationGO:0008213810.014
myelinationGO:0042552740.014
organelle assemblyGO:00709251770.014
nephron epithelium developmentGO:0072009920.014
establishment of protein localization to organelleGO:00725941180.014
Fly
anatomical structure homeostasisGO:00602491450.014
meiotic cell cycleGO:00513211220.014
Fly
cytokine metabolic processGO:0042107710.014
homeostasis of number of cellsGO:00488722100.014
Zebrafish
angiogenesisGO:00015252010.014
negative regulation of immune effector processGO:0002698550.014
defense response to bacteriumGO:00427421190.013
striated muscle cell developmentGO:00550021250.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.013
cellular protein complex assemblyGO:00436231160.013
skeletal muscle organ developmentGO:00605381630.013
positive regulation of protein catabolic processGO:0045732600.013
microtubule based processGO:00070172360.013
regulation of cell motilityGO:20001452360.013
neuroblast fate commitmentGO:001401710.013
purine nucleoside catabolic processGO:00061522050.013
reactive oxygen species metabolic processGO:0072593840.013
lymphocyte mediated immunityGO:00024491390.013
organonitrogen compound biosynthetic processGO:19015661920.013
cell activation involved in immune responseGO:00022631260.013
ubiquitin dependent protein catabolic processGO:00065111290.013
Rat
regulation of cytoplasmic transportGO:19036491120.013
positive regulation of nucleotide metabolic processGO:00459811140.013
morphogenesis of a branching epitheliumGO:00611381930.013
gtp catabolic processGO:00061841430.013
mesenchyme developmentGO:00604851520.013
mesonephric tubule developmentGO:0072164940.013
metanephros developmentGO:0001656790.013
regulation of rna splicingGO:0043484370.013
nerve developmentGO:0021675670.012
regulation of nucleoside metabolic processGO:00091181300.012
negative regulation of t cell activationGO:0050868650.012
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.012
regulation of transferase activityGO:00513382630.012
activation of immune responseGO:00022531380.012
regulation of kinase activityGO:00435492490.012
regulation of cellular response to stressGO:00801351590.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
regulation of cell migrationGO:00303342190.012
nephron developmentGO:00720061090.012
ureteric bud developmentGO:0001657940.012
renal tubule morphogenesisGO:0061333720.012
cation transmembrane transportGO:00986552660.012
cellular lipid metabolic processGO:00442553230.012
multicellular organismal homeostasisGO:00488711640.012
rho protein signal transductionGO:0007266320.012
male meiosisGO:0007140370.012
proteasomal protein catabolic processGO:0010498980.012
Rat
dendrite developmentGO:00163581150.012
regulation of myeloid cell differentiationGO:0045637960.012
male sex differentiationGO:00466611090.012
response to monosaccharideGO:0034284670.012
cytokine mediated signaling pathwayGO:00192211150.012
response to inorganic substanceGO:0010035960.012
response to peptideGO:19016521360.012
oogenesisGO:0048477560.012
regulation of lymphocyte differentiationGO:00456191070.012
regulation of protein transportGO:00512231630.012
positive regulation of protein complex assemblyGO:0031334450.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
endomembrane system organizationGO:00102561470.012
sensory perceptionGO:00076002450.012
cellular response to organonitrogen compoundGO:00714171450.011
mesonephros developmentGO:0001823970.011
negative regulation of wnt signaling pathwayGO:0030178730.011
regulation of osteoblast differentiationGO:0045667670.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
ion transmembrane transportGO:00342203610.011
regulation of cellular protein catabolic processGO:1903362610.011
bmp signaling pathwayGO:0030509930.011
positive regulation of intracellular transportGO:0032388700.011
epithelial tube formationGO:00721751300.011
regulation of innate immune responseGO:0045088910.011
kidney epithelium developmentGO:00720731210.011
regulation of nucleotide catabolic processGO:00308111220.011
retina development in camera type eyeGO:00600411190.011
glycosyl compound catabolic processGO:19016582060.011
regulation of gtp catabolic processGO:00331241130.011
nuclear importGO:0051170950.011
Fly
oligodendrocyte differentiationGO:0048709530.011
regulation of homeostatic processGO:00328441820.011
hexose metabolic processGO:0019318980.011
response to organic cyclic compoundGO:00140701980.011
sensory organ morphogenesisGO:00905962420.011
negative regulation of neuron apoptotic processGO:0043524920.011
epidermis developmentGO:00085441870.011
oocyte anterior posterior axis specificationGO:000731420.011
calcium ion transportGO:00068161590.011
response to oxidative stressGO:00069791230.011
positive regulation of immune effector processGO:00026991070.011
formation of anatomical boundaryGO:004885960.011
cation transportGO:00068123990.011
regulation of neuron projection developmentGO:00109751690.011
internal peptidyl lysine acetylationGO:0018393420.011
central nervous system neuron differentiationGO:00219531620.011
guanosine containing compound catabolic processGO:19010691440.011
cardiocyte differentiationGO:0035051870.011
somatic diversification of immune receptorsGO:0002200530.011
somatic cell dna recombinationGO:0016444510.011
peptidyl lysine acetylationGO:0018394450.011
regulation of mitotic cell cycleGO:00073461260.011
Zebrafish Fly
regulation of t cell differentiationGO:0045580830.011
response to insulinGO:00328681000.011
intracellular mrna localizationGO:000829840.011
microtubule cytoskeleton organizationGO:00002261570.010
organic hydroxy compound metabolic processGO:19016152030.010
histone acetylationGO:0016573410.010
transcription initiation from rna polymerase ii promoterGO:000636780.010
cd4 positive alpha beta t cell activationGO:0035710450.010
male gonad developmentGO:0008584880.010
regulation of protein targetingGO:1903533610.010
epithelial cell proliferationGO:00506731740.010
response to oxygen levelsGO:0070482620.010
tissue homeostasisGO:00018941150.010
respiratory tube developmentGO:00303231670.010
protein ubiquitinationGO:00165671710.010
Rat
endocrine system developmentGO:0035270980.010
alpha beta t cell activationGO:0046631910.010
intracellular receptor signaling pathwayGO:0030522740.010
Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.010
canonical wnt signaling pathwayGO:00600701300.010
renal tubule developmentGO:0061326870.010
regulation of striated muscle cell differentiationGO:0051153810.010
negative regulation of ossificationGO:0030279490.010
compound eye developmentGO:004874910.010
mammary gland epithelium developmentGO:0061180650.010
negative regulation of mapk cascadeGO:0043409650.010
tube formationGO:00351481400.010
regulation of vasculature developmentGO:1901342880.010
natural killer cell activationGO:0030101440.010
positive regulation of immature t cell proliferationGO:003309140.010
sperm motilityGO:0030317470.010
cellular carbohydrate metabolic processGO:00442621190.010

Ube2i disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.054
nervous system diseaseDOID:86300.054
disease of cellular proliferationDOID:1456600.022
eye and adnexa diseaseDOID:149200.019
sensory system diseaseDOID:005015500.019
eye diseaseDOID:561400.019
retinal diseaseDOID:567900.013
retinal degenerationDOID:846600.013
neuropathyDOID:87000.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012