Mus musculus

30 known processes

Ube2h

ubiquitin-conjugating enzyme E2H

(Aliases: Ubc8,E2-20K,AI462483,AI326965,1500009C23Rik,N28148,AW227540,AI181839)

Ube2h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugation or removalGO:00706472070.279
protein modification by small protein conjugationGO:00324461870.150
macromolecule catabolic processGO:00090572810.146
cellular macromolecule catabolic processGO:00442652060.109
purine nucleotide metabolic processGO:00061633020.095
regulation of cell cycleGO:00517262810.076
proteolysis involved in cellular protein catabolic processGO:00516031470.073
response to peptide hormoneGO:00434341270.068
response to peptideGO:19016521360.063
modification dependent macromolecule catabolic processGO:00436321330.059
protein catabolic processGO:00301632210.059
regulation of neuron differentiationGO:00456642810.059
regulation of cellular response to stressGO:00801351590.059
regulation of cell projection organizationGO:00313442060.059
carbohydrate metabolic processGO:00059752300.058
Yeast
regulation of protein localizationGO:00328802310.057
ubiquitin dependent protein catabolic processGO:00065111290.057
ras protein signal transductionGO:0007265770.056
negative regulation of cellular component organizationGO:00511291940.056
cellular response to organonitrogen compoundGO:00714171450.055
organelle assemblyGO:00709251770.055
positive regulation of cellular catabolic processGO:00313311480.053
multicellular organism growthGO:00352641610.053
regulation of membrane potentialGO:00423911920.047
aromatic compound catabolic processGO:00194392860.046
regulation of cellular ketone metabolic processGO:0010565660.045
Yeast
membrane organizationGO:00610242450.044
small gtpase mediated signal transductionGO:0007264970.043
regulation of sequence specific dna binding transcription factor activityGO:00510901060.043
apoptotic signaling pathwayGO:00971903060.042
cellular response to peptideGO:1901653920.042
protein ubiquitinationGO:00165671710.042
purine ribonucleoside triphosphate metabolic processGO:00092052200.041
positive regulation of protein modification processGO:00314012990.041
heterocycle catabolic processGO:00467002800.041
regulation of cellular catabolic processGO:00313292420.040
negative regulation of neuron projection developmentGO:0010977500.040
negative regulation of protein metabolic processGO:00512482820.039
positive regulation of apoptotic processGO:00430652170.038
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.038
nucleotide metabolic processGO:00091173320.037
cell type specific apoptotic processGO:00972852680.037
innate immune responseGO:00450871570.037
regulation of cytokine productionGO:00018172660.036
negative regulation of intracellular signal transductionGO:19025321670.036
positive regulation of programmed cell deathGO:00430682180.036
response to organonitrogen compoundGO:00102432460.036
cellular ketone metabolic processGO:0042180840.035
Yeast
skeletal system developmentGO:00015013560.035
engulfment of apoptotic cellGO:004365230.035
negative regulation of cell proliferationGO:00082852960.035
modification dependent protein catabolic processGO:00199411330.035
regulation of mapk cascadeGO:00434082480.034
cellular nitrogen compound catabolic processGO:00442702800.034
positive regulation of cellular amine metabolic processGO:003324050.033
protein maturationGO:00516041760.033
cytokine productionGO:00018163190.033
purine ribonucleotide metabolic processGO:00091502900.033
regulation of protein serine threonine kinase activityGO:00719001570.032
negative regulation of nervous system developmentGO:00519611560.032
mitochondrion distributionGO:004831140.032
positive regulation of cellular amino acid metabolic processGO:004576430.031
regulation of cellular amine metabolic processGO:0033238200.031
ribonucleoside triphosphate metabolic processGO:00091992200.031
olfactory learningGO:000835520.031
mapk cascadeGO:00001652810.031
organic cyclic compound catabolic processGO:19013612950.030
regulation of transferase activityGO:00513382630.030
negative regulation of molecular functionGO:00440922580.030
ribose phosphate metabolic processGO:00196932910.029
nucleoside catabolic processGO:00091642060.029
nucleoside phosphate metabolic processGO:00067533380.029
organophosphate catabolic processGO:00464342320.029
cellular response to peptide hormone stimulusGO:0071375920.028
male gamete generationGO:00482322850.028
intrinsic apoptotic signaling pathwayGO:00971931320.028
regulation of cellular amino acid metabolic processGO:000652150.028
regulation of neuron projection developmentGO:00109751690.028
protein localization to organelleGO:00333651850.027
generation of precursor metabolites and energyGO:00060911030.027
neuronal action potentialGO:0019228540.027
mitochondrion organizationGO:00070051340.027
dna metabolic processGO:00062593030.027
learning or memoryGO:00076111480.027
purine containing compound metabolic processGO:00725213110.027
glycosyl compound metabolic processGO:19016572460.027
posttranscriptional regulation of gene expressionGO:00106081550.027
regulation of cellular carbohydrate metabolic processGO:0010675750.027
Yeast
cellular response to hormone stimulusGO:00328701500.026
negative regulation of phosphorus metabolic processGO:00105631840.026
ribonucleoside catabolic processGO:00424542060.026
nucleoside triphosphate catabolic processGO:00091432050.026
adaptive immune responseGO:00022501550.026
dephosphorylationGO:00163111290.026
regulation of cellular component sizeGO:00325351210.026
cellular response to dna damage stimulusGO:00069742070.026
actin cytoskeleton organizationGO:00300362200.026
spermatogenesisGO:00072832840.026
muscle tissue developmentGO:00605373080.026
carbohydrate transportGO:0008643620.026
regulation of hydrolase activityGO:00513362460.026
positive regulation of macroautophagyGO:001623930.025
ribonucleotide metabolic processGO:00092592910.025
negative regulation of phosphorylationGO:00423261660.025
maintenance of locationGO:0051235890.025
regulation of organelle organizationGO:00330432890.025
immune effector processGO:00022523210.025
muscle cell differentiationGO:00426922610.025
nucleoside phosphate catabolic processGO:19012922220.025
negative regulation of kinase activityGO:0033673810.025
cellular amine metabolic processGO:0044106440.025
amine metabolic processGO:0009308450.025
negative regulation of cell cycleGO:00457861230.024
response to insulinGO:00328681000.024
purine nucleoside catabolic processGO:00061522050.024
transmembrane transportGO:00550854120.024
peptidyl amino acid modificationGO:00181933360.024
action potentialGO:0001508780.023
gtp metabolic processGO:00460391440.023
regulation of engulfment of apoptotic cellGO:190107420.023
cerebellum developmentGO:0021549770.023
regulation of proteolysisGO:00301621640.023
purine ribonucleoside triphosphate catabolic processGO:00092071990.023
circadian rhythmGO:00076231140.023
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.023
inositol phosphate catabolic processGO:007154540.023
positive regulation of reactive oxygen species metabolic processGO:2000379110.022
ribonucleoside metabolic processGO:00091192450.022
response to nutrient levelsGO:00316671090.022
ossificationGO:00015032160.022
purine nucleoside metabolic processGO:00422782410.022
organonitrogen compound catabolic processGO:19015652640.022
response to oxidative stressGO:00069791230.022
negative regulation of growthGO:0045926990.022
negative regulation of cell developmentGO:00107211690.022
cellular carbohydrate metabolic processGO:00442621190.022
Yeast
regulation of insulin receptor signaling pathwayGO:0046626210.022
nucleobase containing small molecule metabolic processGO:00550863520.021
cell adhesionGO:00071553290.021
symbiosis encompassing mutualism through parasitismGO:0044403830.021
regulation of establishment of protein localizationGO:00702011810.021
cellular amino acid metabolic processGO:00065201030.021
reactive oxygen species metabolic processGO:0072593840.021
regulation of body fluid levelsGO:00508781620.021
regulation of kinase activityGO:00435492490.021
purine nucleoside triphosphate metabolic processGO:00091442260.021
regulation of secretionGO:00510462740.021
mitotic cell cycleGO:00002781950.021
cellular response to starvationGO:0009267570.021
regulation of bindingGO:00510981110.021
negative regulation of cellular amine metabolic processGO:003323910.021
regulation of anatomical structure sizeGO:00900661780.020
regulation of protein kinase activityGO:00458592320.020
phosphorylated carbohydrate dephosphorylationGO:004683840.020
defense response to other organismGO:00985421970.020
regulation of reactive oxygen species biosynthetic processGO:190342620.020
cellular response to insulin stimulusGO:0032869780.020
regulation of cell activationGO:00508652890.020
rho protein signal transductionGO:0007266320.020
regulation of lymphocyte activationGO:00512492400.020
multicellular organismal signalingGO:0035637910.020
small molecule catabolic processGO:0044282710.020
regulation of ras protein signal transductionGO:00465781140.020
metencephalon developmentGO:0022037890.020
alcohol metabolic processGO:00060661160.020
glycosyl compound catabolic processGO:19016582060.020
regulation of cellular component biogenesisGO:00440871810.020
locomotory behaviorGO:00076261950.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
cellular response to external stimulusGO:0071496880.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.020
single organism cell adhesionGO:00986021560.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
leukocyte differentiationGO:00025213420.019
positive regulation of hydrolase activityGO:00513451480.019
nucleoside metabolic processGO:00091162460.019
skeletal muscle organ developmentGO:00605381630.019
digestive tract developmentGO:00485651900.019
regulation of system processGO:00440572000.019
positive regulation of reactive oxygen species biosynthetic processGO:190342820.019
oxidation reduction processGO:00551143420.019
microtubule based processGO:00070172360.019
positive regulation of mapk cascadeGO:00434101700.019
reactive oxygen species biosynthetic processGO:190340980.019
myeloid leukocyte differentiationGO:00025731190.019
nucleotide catabolic processGO:00091662170.018
negative regulation of phosphate metabolic processGO:00459361840.018
developmental maturationGO:00217001930.018
plasma membrane organizationGO:0007009900.018
positive regulation of cell deathGO:00109422240.018
transmission of nerve impulseGO:0019226760.018
regulation of intracellular protein transportGO:0033157820.018
microtubule cytoskeleton organizationGO:00002261570.018
regulation of leukocyte differentiationGO:19021051590.018
cognitionGO:00508901490.018
response to endoplasmic reticulum stressGO:0034976530.018
positive regulation of nucleotide catabolic processGO:0030813880.017
syncytiotrophoblast cell differentiation involved in labyrinthine layer developmentGO:006071520.017
leukocyte mediated immunityGO:00024431740.017
regulation of map kinase activityGO:00434051200.017
positive regulation of protein phosphorylationGO:00019342420.017
insulin receptor signaling pathwayGO:0008286490.017
sensory perceptionGO:00076002450.017
rhythmic processGO:00485111740.017
myeloid cell differentiationGO:00300992330.017
compound eye developmentGO:004874910.017
lipid modificationGO:0030258650.017
regulation of cell motilityGO:20001452360.017
cell growthGO:00160491300.017
retrograde transport endosome to golgiGO:004214720.017
regulation of cell migrationGO:00303342190.017
negative regulation of protein modification processGO:00314001630.017
intracellular protein transportGO:00068862040.017
germ cell developmentGO:00072811850.016
regulation of vesicle mediated transportGO:00606271390.016
reactive nitrogen species metabolic processGO:200105700.016
carbohydrate derivative biosynthetic processGO:19011371830.016
carbohydrate derivative catabolic processGO:19011362310.016
regulation of defense responseGO:00313472330.016
response to molecule of bacterial originGO:00022371430.016
positive regulation of gtpase activityGO:0043547850.016
protein processingGO:00164851630.016
purine ribonucleotide catabolic processGO:00091542080.016
lymphocyte mediated immunityGO:00024491390.016
cellular response to acid chemicalGO:0071229680.016
striated muscle tissue developmentGO:00147062930.016
regulation of protein catabolic processGO:00421761080.016
production of molecular mediator of immune responseGO:00024401030.016
regulation of intracellular transportGO:00323861590.015
wnt signaling pathwayGO:00160551880.015
cellular response to extracellular stimulusGO:0031668810.015
negative regulation of protein phosphorylationGO:00019331260.015
rna processingGO:00063961050.015
mitotic cell cycle processGO:19030471590.015
blood vessel morphogenesisGO:00485142850.015
cation transportGO:00068123990.015
negative regulation of neuron differentiationGO:00456651010.015
cytokine biosynthetic processGO:0042089680.015
cellular protein catabolic processGO:00442571550.015
negative regulation of transferase activityGO:0051348850.015
regulation of cell sizeGO:0008361720.015
purine nucleotide catabolic processGO:00061952110.015
regulation of cell growthGO:0001558910.015
actin filament organizationGO:00070151130.015
methylationGO:00322591340.015
protein targetingGO:00066051430.015
endomembrane system organizationGO:00102561470.015
glycerolipid metabolic processGO:00464861220.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
regulation of protein transportGO:00512231630.015
positive regulation of cytokine productionGO:00018191740.015
cell maturationGO:00484691270.015
regulation of mitotic cell cycleGO:00073461260.015
positive regulation of proteolysisGO:0045862850.015
regulation of protein bindingGO:0043393600.015
regulation of neurotrophin trk receptor signaling pathwayGO:005138640.015
regulation of cytoskeleton organizationGO:00514931220.015
developmental growth involved in morphogenesisGO:00605601380.014
gland developmentGO:00487323300.014
t cell activationGO:00421102890.014
monocarboxylic acid metabolic processGO:00327871910.014
cytoplasmic transportGO:00164822340.014
establishment of protein localization to membraneGO:0090150540.014
dna repairGO:00062811070.014
wound healingGO:00420601570.014
neuron projection extensionGO:1990138640.014
positive regulation of growthGO:00459271040.014
regulation of response to woundingGO:19030341890.014
positive regulation of nucleotide metabolic processGO:00459811140.014
regulation of ion transportGO:00432692150.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
gtp catabolic processGO:00061841430.014
lateral inhibitionGO:004633110.014
Fly
purine ribonucleoside metabolic processGO:00461282410.014
regulation of nucleotide metabolic processGO:00061401690.014
cellular protein complex assemblyGO:00436231160.014
forebrain developmentGO:00309003020.014
organelle localizationGO:00516401790.014
nucleoside triphosphate metabolic processGO:00091412300.014
regulation of protein processingGO:0070613960.014
regulation of purine nucleotide metabolic processGO:19005421690.014
nitrogen compound transportGO:00717052710.014
cellular homeostasisGO:00197252400.014
myeloid cell homeostasisGO:00022621140.014
muscle system processGO:00030121410.014
endocytosisGO:00068971680.013
metal ion homeostasisGO:00550651890.013
response to extracellular stimulusGO:00099911270.013
membrane fusionGO:0061025380.013
regulation of myeloid cell differentiationGO:0045637960.013
regulation of carbohydrate metabolic processGO:0006109750.013
Yeast
glucose homeostasisGO:00425931280.013
protein localization to membraneGO:00726571080.013
lipid transportGO:0006869980.013
blood circulationGO:00080151950.013
regulation of apoptotic signaling pathwayGO:20012331970.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.013
monosaccharide transportGO:0015749580.013
cellular response to nutrient levelsGO:0031669640.013
negative regulation of cell projection organizationGO:0031345560.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
regulation of transmembrane transportGO:00347621280.013
negative regulation of phagocytosisGO:005076540.013
organophosphate biosynthetic processGO:00904071220.013
positive regulation of nervous system developmentGO:00519622210.013
nucleoside phosphate biosynthetic processGO:1901293790.013
hormone secretionGO:00468791280.013
cellular response to lipidGO:00713961450.013
ribonucleotide catabolic processGO:00092612080.013
regulation of t cell activationGO:00508631700.013
chemotaxisGO:00069352470.013
divalent inorganic cation transportGO:00725111780.012
regulation of cellular protein catabolic processGO:1903362610.012
negative regulation of cellular protein metabolic processGO:00322692470.012
protein polyubiquitinationGO:0000209330.012
Human
carbohydrate homeostasisGO:00335001280.012
establishment of protein localization to organelleGO:00725941180.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
digestive tract morphogenesisGO:00485461470.012
central nervous system neuron differentiationGO:00219531620.012
histone modificationGO:00165701590.012
cellular component assembly involved in morphogenesisGO:00109271390.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
positive regulation of protein catabolic processGO:0045732600.012
g protein coupled receptor signaling pathwayGO:00071862430.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
lymphocyte differentiationGO:00300982420.012
purine ribonucleoside catabolic processGO:00461302050.012
response to light stimulusGO:00094161350.012
regionalizationGO:00030023370.012
proteasomal protein catabolic processGO:0010498980.012
lipid biosynthetic processGO:00086101790.012
protein importGO:00170381010.012
multicellular organismal homeostasisGO:00488711640.012
regulation of protein modification by small protein conjugation or removalGO:1903320570.012
phagocytosisGO:0006909660.012
oocyte constructionGO:000730820.012
meiotic cell cycle processGO:1903046770.012
skeletal muscle cell differentiationGO:0035914660.012
positive regulation of immune effector processGO:00026991070.012
phospholipid metabolic processGO:0006644870.012
glycoprotein metabolic processGO:00091001160.012
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.012
autophagic vacuole assemblyGO:0000045130.012
defense response to bacteriumGO:00427421190.012
cerebellar cortex morphogenesisGO:0021696320.012
oocyte axis specificationGO:000730920.012
connective tissue developmentGO:00614481790.012
regulation of extent of cell growthGO:0061387520.012
regulation of hormone levelsGO:00108172110.012
b cell activationGO:00421131610.012
response to growth factorGO:00708481980.011
myelinationGO:0042552740.011
extracellular matrix organizationGO:00301981470.011
cellular metal ion homeostasisGO:00068751510.011
positive regulation of cell activationGO:00508671580.011
cytokine metabolic processGO:0042107710.011
oogenesisGO:0048477560.011
regulation of lipid metabolic processGO:00192161180.011
protein autophosphorylationGO:0046777610.011
cation transmembrane transportGO:00986552660.011
negative regulation of map kinase activityGO:0043407340.011
cellular chemical homeostasisGO:00550822150.011
ion transmembrane transportGO:00342203610.011
regulation of glucose transportGO:0010827320.011
inflammatory responseGO:00069542440.011
regulation of wnt signaling pathwayGO:00301111230.011
positive regulation of cell developmentGO:00107202370.011
limb developmentGO:00601731660.011
organonitrogen compound biosynthetic processGO:19015661920.011
peptidyl tyrosine phosphorylationGO:00181081430.011
striated muscle cell developmentGO:00550021250.011
response to radiationGO:00093141650.011
stem cell differentiationGO:00488632680.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
protein localization to nucleusGO:00345041210.011
response to inactivityGO:001485440.011
axonogenesisGO:00074092740.011
organic hydroxy compound metabolic processGO:19016152030.011
dendrite developmentGO:00163581150.011
negative regulation of synapse assemblyGO:005196430.011
protein methylationGO:0006479810.011
guanosine containing compound catabolic processGO:19010691440.011
skin developmentGO:00435882200.011
autophagyGO:0006914450.011
hematopoietic progenitor cell differentiationGO:00022441430.011
sensory organ morphogenesisGO:00905962420.011
respiratory system developmentGO:00605411900.011
positive regulation of defense responseGO:00313491240.011
purine containing compound biosynthetic processGO:0072522700.011
regulation of cytokine biosynthetic processGO:0042035590.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
regulation of nucleotide catabolic processGO:00308111220.011
glial cell differentiationGO:00100011310.011
embryonic organ morphogenesisGO:00485622760.011
response to inorganic substanceGO:0010035960.011
actin filament polymerizationGO:0030041440.011
nucleotide biosynthetic processGO:0009165780.011
regulation of leukocyte mediated immunityGO:00027031040.011
midgut developmentGO:000749440.011
regulation of actin cytoskeleton organizationGO:0032956840.010
lung developmentGO:00303241640.010
cell activation involved in immune responseGO:00022631260.010
response to organic cyclic compoundGO:00140701980.010
axon ensheathmentGO:0008366760.010
response to granulocyte macrophage colony stimulating factorGO:009701230.010
single organism nuclear importGO:1902593950.010
positive regulation of gtp catabolic processGO:0033126850.010
cellular response to biotic stimulusGO:0071216920.010
phosphatidylinositol metabolic processGO:0046488450.010
exocytosisGO:00068871210.010
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.010
establishment or maintenance of cytoskeleton polarityGO:003095220.010
canonical wnt signaling pathwayGO:00600701300.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
actin polymerization or depolymerizationGO:0008154540.010
regulation of cell cycle processGO:00105641600.010
glycerophospholipid metabolic processGO:0006650710.010
pole plasm assemblyGO:000731520.010
regulation of multi organism processGO:00439001110.010
viral transcriptionGO:001908330.010
cellular response to epidermal growth factor stimulusGO:007136440.010
myotube differentiationGO:00149021050.010
lipid homeostasisGO:0055088630.010
glucan metabolic processGO:0044042320.010
regulation of interleukin 8 productionGO:003267730.010
response to epidermal growth factorGO:007084940.010

Ube2h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
central nervous system diseaseDOID:33100.016
cardiovascular system diseaseDOID:128700.015
disease of metabolismDOID:001466700.015
musculoskeletal system diseaseDOID:1700.012
connective tissue diseaseDOID:6500.012