IMP: Integrative Multi-species Prediction

Mus musculus

35 known processes

Ulk4

unc-51-like kinase 4 (C. elegans)

(Aliases: A730098P15,4932415A06Rik)

Entrez: 209012
Ensembl: ENSMUSG00000040936
UniProtKB: E9Q2P5
UniProtKB: Q3V129

Process Predictions
Disease Predictions

Ulk4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cilium movement	GO:0003341	28	0.998
epithelial cilium movement	GO:0003351	12	0.995
cilium assembly	GO:0042384	81	0.991
microtubule based movement	GO:0007018	84	0.983
cilium morphogenesis	GO:0060271	102	0.959
cellular component assembly involved in morphogenesis	GO:0010927	139	0.868
ventricular system development	GO:0021591	27	0.852
organelle assembly	GO:0070925	177	0.529
microtubule based process	GO:0007017	236	0.474
positive regulation of cilium movement	GO:0003353	1	0.204
spermatogenesis	GO:0007283	284	0.200
spermatid differentiation	GO:0048515	115	0.181
spermatid development	GO:0007286	108	0.141
nucleus accumbens development	GO:0021768	1	0.100
9 cis retinoic acid biosynthetic process	GO:0042904	5	0.085
kidney development	GO:0001822	213	0.072
axoneme assembly	GO:0035082	15	0.061
regulation of apoptotic signaling pathway	GO:2001233	197	0.052
male gamete generation	GO:0048232	285	0.051
protein polyglycylation	GO:0018094	3	0.048
intrinsic apoptotic signaling pathway	GO:0097193	132	0.047
regulation of cellular response to stress	GO:0080135	159	0.041	Human
respiratory tube development	GO:0030323	167	0.041
cellular response to oxidative stress	GO:0034599	76	0.040
alcohol metabolic process	GO:0006066	116	0.037
microtubule severing	GO:0051013	5	0.036
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.036
monocarboxylic acid biosynthetic process	GO:0072330	61	0.033
response to acid chemical	GO:0001101	111	0.033
sensory organ morphogenesis	GO:0090596	242	0.031
righting reflex	GO:0060013	9	0.030
cellular aldehyde metabolic process	GO:0006081	12	0.029
cellular homeostasis	GO:0019725	240	0.028
regulation of hormone levels	GO:0010817	211	0.028
embryonic digestive tract development	GO:0048566	27	0.028
negative regulation of intracellular signal transduction	GO:1902532	167	0.028
peptidyl glutamic acid modification	GO:0018200	13	0.028
ras protein signal transduction	GO:0007265	77	0.027
positive regulation of cell death	GO:0010942	224	0.026
cellular amino acid metabolic process	GO:0006520	103	0.026
apoptotic signaling pathway	GO:0097190	306	0.026
lipid biosynthetic process	GO:0008610	179	0.023
regulation of neuron differentiation	GO:0045664	281	0.023	Human
cellular ketone metabolic process	GO:0042180	84	0.022
limbic system development	GO:0021761	72	0.022
regulation of organelle organization	GO:0033043	289	0.022
respiratory system development	GO:0060541	190	0.021
response to oxidative stress	GO:0006979	123	0.021
lung development	GO:0030324	164	0.021
nucleobase containing small molecule metabolic process	GO:0055086	352	0.020
dna metabolic process	GO:0006259	303	0.020
renal system development	GO:0072001	225	0.018
organic acid biosynthetic process	GO:0016053	86	0.018
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.018
urogenital system development	GO:0001655	261	0.018
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	34	0.018
telencephalon development	GO:0021537	186	0.018
embryonic appendage morphogenesis	GO:0035113	126	0.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway	GO:1902176	4	0.017
anatomical structure maturation	GO:0071695	49	0.017
positive regulation of apoptotic process	GO:0043065	217	0.017
limb development	GO:0060173	166	0.017
regulation of response to oxidative stress	GO:1902882	19	0.017
regulation of hydrolase activity	GO:0051336	246	0.017
macromolecule catabolic process	GO:0009057	281	0.016
cellular lipid metabolic process	GO:0044255	323	0.016
stem cell differentiation	GO:0048863	268	0.016
epithelial tube morphogenesis	GO:0060562	303	0.016
9 cis retinoic acid metabolic process	GO:0042905	5	0.016
reactive oxygen species metabolic process	GO:0072593	84	0.016
regulation of cellular amino acid metabolic process	GO:0006521	5	0.015
regulation of cellular response to oxidative stress	GO:1900407	19	0.015
oocyte axis specification	GO:0007309	2	0.015
organelle fission	GO:0048285	170	0.015
ribonucleoside metabolic process	GO:0009119	245	0.015
nuclear division	GO:0000280	158	0.015
positive regulation of cellular amine metabolic process	GO:0033240	5	0.015
positive regulation of programmed cell death	GO:0043068	218	0.015
gland development	GO:0048732	330	0.015
terpenoid biosynthetic process	GO:0016114	7	0.015
primary alcohol metabolic process	GO:0034308	11	0.015
purine ribonucleoside metabolic process	GO:0046128	241	0.014
defecation	GO:0030421	1	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.014
nucleoside metabolic process	GO:0009116	246	0.014
embryonic organ morphogenesis	GO:0048562	276	0.014
membrane organization	GO:0061024	245	0.014
organonitrogen compound catabolic process	GO:1901565	264	0.014
lateral inhibition	GO:0046331	1	0.014
regulation of cellular ketone metabolic process	GO:0010565	66	0.014
cellular response to lipid	GO:0071396	145	0.014
amine metabolic process	GO:0009308	45	0.014
negative regulation of oxidative stress induced cell death	GO:1903202	9	0.014
camera type eye development	GO:0043010	266	0.014
negative regulation of cellular response to oxidative stress	GO:1900408	10	0.014
asymmetric stem cell division	GO:0098722	3	0.014
protein localization to organelle	GO:0033365	185	0.013
nucleotide metabolic process	GO:0009117	332	0.013
posttranscriptional regulation of gene expression	GO:0010608	155	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.013
carbohydrate derivative catabolic process	GO:1901136	231	0.013
embryonic limb morphogenesis	GO:0030326	126	0.013
ribonucleotide metabolic process	GO:0009259	291	0.013
regulation of endothelial cell proliferation	GO:0001936	23	0.013
oocyte anterior posterior axis specification	GO:0007314	2	0.012
ureter maturation	GO:0035799	4	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.012
appendage morphogenesis	GO:0035107	149	0.012
locomotory behavior	GO:0007626	195	0.012
regulation of cell adhesion	GO:0030155	154	0.012
ribonucleotide catabolic process	GO:0009261	208	0.012
meiotic cell cycle	GO:0051321	122	0.012
cellular response to dna damage stimulus	GO:0006974	207	0.012
oocyte construction	GO:0007308	2	0.012
carbohydrate derivative biosynthetic process	GO:1901137	183	0.012
neuromuscular process controlling balance	GO:0050885	59	0.012
muscle tissue development	GO:0060537	308	0.012
fertilization	GO:0009566	127	0.012
cellular response to organonitrogen compound	GO:0071417	145	0.012
nucleoside phosphate catabolic process	GO:1901292	222	0.011
mesodermal cell migration	GO:0008078	4	0.011
nucleoside phosphate metabolic process	GO:0006753	338	0.011
monocarboxylic acid metabolic process	GO:0032787	191	0.011
rac protein signal transduction	GO:0016601	13	0.011
regionalization	GO:0003002	337	0.011
developmental maturation	GO:0021700	193	0.011
sulfur compound biosynthetic process	GO:0044272	37	0.011
purine nucleoside catabolic process	GO:0006152	205	0.011
purine containing compound metabolic process	GO:0072521	311	0.011
regulation of cellular catabolic process	GO:0031329	242	0.011
cellularization	GO:0007349	1	0.011
carboxylic acid biosynthetic process	GO:0046394	86	0.011
purine nucleoside metabolic process	GO:0042278	241	0.011
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.011
carbohydrate metabolic process	GO:0005975	230	0.011
glycosyl compound metabolic process	GO:1901657	246	0.011
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.011
embryonic camera type eye development	GO:0031076	36	0.011
carbohydrate biosynthetic process	GO:0016051	74	0.011
response to drug	GO:0042493	75	0.011
small gtpase mediated signal transduction	GO:0007264	97	0.011
organic cyclic compound catabolic process	GO:1901361	295	0.011
cellular amine metabolic process	GO:0044106	44	0.011
striated muscle tissue development	GO:0014706	293	0.011
ear development	GO:0043583	200	0.011
intracellular mrna localization	GO:0008298	4	0.011
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.011
limb morphogenesis	GO:0035108	149	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
gtp catabolic process	GO:0006184	143	0.011
anatomical structure homeostasis	GO:0060249	145	0.010
protein autophosphorylation	GO:0046777	61	0.010
protein catabolic process	GO:0030163	221	0.010
ribonucleoside catabolic process	GO:0042454	206	0.010
ribose phosphate metabolic process	GO:0019693	291	0.010
cellular chemical homeostasis	GO:0055082	215	0.010
diterpenoid biosynthetic process	GO:0016102	7	0.010
appendage development	GO:0048736	166	0.010
inorganic cation transmembrane transport	GO:0098662	207	0.010
reactive oxygen species biosynthetic process	GO:1903409	8	0.010
meiotic cell cycle process	GO:1903046	77	0.010
microtubule cytoskeleton organization	GO:0000226	157	0.010	Human
compound eye development	GO:0048749	1	0.010
cation homeostasis	GO:0055080	212	0.010

Ulk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.041
nervous system disease	DOID:863	0.041
inherited metabolic disorder	DOID:655	0.019
disease of metabolism	DOID:0014667	0.019
sensory system disease	DOID:0050155	0.016
disease of cellular proliferation	DOID:14566	0.016
cancer	DOID:162	0.016
organ system cancer	DOID:0050686	0.016
primary ciliary dyskinesia	DOID:9562	0.013
eye and adnexa disease	DOID:1492	0.012
eye disease	DOID:5614	0.011

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