IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Echs1

enoyl Coenzyme A hydratase, short chain, 1, mitochondrial

(Aliases: C80529)

Entrez: 93747
Ensembl: ENSMUSG00000025465
UniProtKB: Q8BH95

Process Predictions
Disease Predictions

Echs1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid catabolic process	GO:0046395	51	0.984	Rat
lipid oxidation	GO:0034440	29	0.936	Rat
organic acid catabolic process	GO:0016054	51	0.933	Rat
fatty acid oxidation	GO:0019395	28	0.924	Rat
acyl coa metabolic process	GO:0006637	19	0.891
small molecule catabolic process	GO:0044282	71	0.863	Rat
sulfur compound metabolic process	GO:0006790	100	0.812
oxidation reduction process	GO:0055114	342	0.747	Rat
thioester metabolic process	GO:0035383	19	0.713
cellular lipid catabolic process	GO:0044242	52	0.710	Rat
fatty acid beta oxidation	GO:0006635	16	0.672	Rat
coenzyme metabolic process	GO:0006732	52	0.671
cellular amino acid metabolic process	GO:0006520	103	0.669
monocarboxylic acid catabolic process	GO:0072329	27	0.481	Rat
monocarboxylic acid metabolic process	GO:0032787	191	0.349	Rat
mitochondrial transport	GO:0006839	36	0.339
cellular lipid metabolic process	GO:0044255	323	0.196	Rat
alpha amino acid metabolic process	GO:1901605	59	0.190
cofactor metabolic process	GO:0051186	80	0.188
lipid catabolic process	GO:0016042	69	0.171	Rat
cellular amino acid catabolic process	GO:0009063	25	0.157
protein homooligomerization	GO:0051260	43	0.155
membrane organization	GO:0061024	245	0.154
mitochondrial membrane organization	GO:0007006	26	0.151
protein oligomerization	GO:0051259	67	0.138
glutamine family amino acid biosynthetic process	GO:0009084	2	0.129
lipid modification	GO:0030258	65	0.116	Rat
fatty acid metabolic process	GO:0006631	121	0.113	Rat
cellular modified amino acid metabolic process	GO:0006575	63	0.109
organonitrogen compound biosynthetic process	GO:1901566	192	0.109
amp metabolic process	GO:0046033	4	0.099
deoxyribose phosphate metabolic process	GO:0019692	9	0.094
mitochondrion organization	GO:0007005	134	0.093
small molecule biosynthetic process	GO:0044283	132	0.092
glycosyl compound metabolic process	GO:1901657	246	0.083
nucleoside phosphate metabolic process	GO:0006753	338	0.076
glutamine family amino acid metabolic process	GO:0009064	15	0.074
nucleobase containing small molecule metabolic process	GO:0055086	352	0.070
nucleoside metabolic process	GO:0009116	246	0.068
succinyl coa metabolic process	GO:0006104	1	0.063
cellular ketone metabolic process	GO:0042180	84	0.062
purine deoxyribonucleoside triphosphate metabolic process	GO:0009215	7	0.060
purine ribonucleotide metabolic process	GO:0009150	290	0.060
purine containing compound metabolic process	GO:0072521	311	0.059
regulation of mitochondrion organization	GO:0010821	27	0.058
branched chain amino acid catabolic process	GO:0009083	2	0.053
negative regulation of cellular component organization	GO:0051129	194	0.052
glutamate biosynthetic process	GO:0006537	2	0.050
purine ribonucleoside metabolic process	GO:0046128	241	0.050
transmembrane transport	GO:0055085	412	0.048
ossification	GO:0001503	216	0.044
apoptotic mitochondrial changes	GO:0008637	48	0.042
protein processing	GO:0016485	163	0.041
intracellular protein transport	GO:0006886	204	0.040
hepaticobiliary system development	GO:0061008	67	0.039
nucleotide metabolic process	GO:0009117	332	0.039
carbohydrate derivative biosynthetic process	GO:1901137	183	0.038
endocytosis	GO:0006897	168	0.038
cellular amine metabolic process	GO:0044106	44	0.038
carboxylic acid biosynthetic process	GO:0046394	86	0.038
negative regulation of cell proliferation	GO:0008285	296	0.038
regulation of cellular ketone metabolic process	GO:0010565	66	0.036
regulation of apoptotic signaling pathway	GO:2001233	197	0.036
regulation of hormone levels	GO:0010817	211	0.036
regulation of cellular amino acid metabolic process	GO:0006521	5	0.036
purine nucleoside metabolic process	GO:0042278	241	0.035
gland development	GO:0048732	330	0.035
protein tetramerization	GO:0051262	23	0.035
cation transport	GO:0006812	399	0.035
purine nucleotide metabolic process	GO:0006163	302	0.034
protein maturation	GO:0051604	176	0.033
nucleoside phosphate biosynthetic process	GO:1901293	79	0.033
regulation of secretion by cell	GO:1903530	249	0.033
deoxyribonucleoside triphosphate metabolic process	GO:0009200	9	0.033
alpha amino acid biosynthetic process	GO:1901607	15	0.033
negative regulation of cellular protein metabolic process	GO:0032269	247	0.033
lipid biosynthetic process	GO:0008610	179	0.033
peptide metabolic process	GO:0006518	46	0.032
cellular amide metabolic process	GO:0043603	58	0.032
ribose phosphate biosynthetic process	GO:0046390	59	0.032
alpha amino acid catabolic process	GO:1901606	18	0.032
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.032
negative regulation of organelle organization	GO:0010639	90	0.031
glutamate metabolic process	GO:0006536	9	0.031
response to organic cyclic compound	GO:0014070	198	0.030
glycerol ether metabolic process	GO:0006662	2	0.030
protein localization to organelle	GO:0033365	185	0.030
t cell activation	GO:0042110	289	0.029
carbohydrate derivative catabolic process	GO:1901136	231	0.029
quinone metabolic process	GO:1901661	7	0.029
ribonucleotide metabolic process	GO:0009259	291	0.027
regulation of organelle organization	GO:0033043	289	0.027
ribonucleoside metabolic process	GO:0009119	245	0.027
response to oxygen levels	GO:0070482	62	0.027
response to organonitrogen compound	GO:0010243	246	0.026
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.026
blood vessel morphogenesis	GO:0048514	285	0.026
hormone metabolic process	GO:0042445	86	0.026
response to hypoxia	GO:0001666	58	0.026
negative regulation of protein processing	GO:0010955	79	0.026
organophosphate biosynthetic process	GO:0090407	122	0.026
glutathione metabolic process	GO:0006749	16	0.026
fatty acid alpha oxidation	GO:0001561	2	0.026
response to extracellular stimulus	GO:0009991	127	0.025
cytoplasmic transport	GO:0016482	234	0.025
macromolecule catabolic process	GO:0009057	281	0.025
response to starvation	GO:0042594	65	0.025
fatty acid catabolic process	GO:0009062	25	0.025	Rat
regulation of cellular amine metabolic process	GO:0033238	20	0.024
ion transmembrane transport	GO:0034220	361	0.024
organic acid biosynthetic process	GO:0016053	86	0.023
ether lipid metabolic process	GO:0046485	2	0.023
male sex differentiation	GO:0046661	109	0.023
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.023
amine metabolic process	GO:0009308	45	0.023
nucleotide biosynthetic process	GO:0009165	78	0.022
female sex differentiation	GO:0046660	84	0.022
ether metabolic process	GO:0018904	2	0.022
regulation of mitochondrial membrane permeability involved in apoptotic process	GO:1902108	14	0.022
posttranscriptional regulation of gene expression	GO:0010608	155	0.022
ribonucleotide biosynthetic process	GO:0009260	59	0.021
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.021
regulation of lymphocyte activation	GO:0051249	240	0.021
cation transmembrane transport	GO:0098655	266	0.021
extracellular structure organization	GO:0043062	148	0.021
very long chain fatty acid metabolic process	GO:0000038	8	0.020
positive regulation of mitochondrial membrane permeability	GO:0035794	12	0.020
tricarboxylic acid metabolic process	GO:0072350	5	0.020
regulation of ossification	GO:0030278	112	0.020
dicarboxylic acid metabolic process	GO:0043648	18	0.020
positive regulation of secretion by cell	GO:1903532	114	0.020
development of primary sexual characteristics	GO:0045137	143	0.020
maintenance of location	GO:0051235	89	0.019
regulation of protein processing	GO:0070613	96	0.019
ribose phosphate metabolic process	GO:0019693	291	0.019
response to decreased oxygen levels	GO:0036293	59	0.019
gonad development	GO:0008406	141	0.019
nucleoside diphosphate biosynthetic process	GO:0009133	2	0.019
regulation of intracellular transport	GO:0032386	159	0.019
organic hydroxy compound metabolic process	GO:1901615	203	0.019
transmission of nerve impulse	GO:0019226	76	0.019
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.018
positive regulation of mitochondrial membrane permeability involved in apoptotic process	GO:1902110	11	0.018
action potential	GO:0001508	78	0.018
regulation of vesicle mediated transport	GO:0060627	139	0.018
negative regulation of intracellular signal transduction	GO:1902532	167	0.018
regulation of membrane potential	GO:0042391	192	0.018
regulation of secretion	GO:0051046	274	0.018
skeletal system morphogenesis	GO:0048705	203	0.017
purine ribonucleoside biosynthetic process	GO:0046129	19	0.017
reactive nitrogen species metabolic process	GO:2001057	0	0.017
coenzyme biosynthetic process	GO:0009108	23	0.017
nephron development	GO:0072006	109	0.017
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.017
organonitrogen compound catabolic process	GO:1901565	264	0.017
t cell proliferation	GO:0042098	120	0.017
atp metabolic process	GO:0046034	75	0.017
homeostasis of number of cells	GO:0048872	210	0.017
protein homotetramerization	GO:0051289	12	0.017
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.017
regulation of mapk cascade	GO:0043408	248	0.016
negative regulation of protein metabolic process	GO:0051248	282	0.016
protein catabolic process	GO:0030163	221	0.016
lymphocyte differentiation	GO:0030098	242	0.016
purine containing compound biosynthetic process	GO:0072522	70	0.016
regulation of protein maturation	GO:1903317	96	0.016
lymphocyte proliferation	GO:0046651	164	0.016
mapk cascade	GO:0000165	281	0.016
nucleoside monophosphate metabolic process	GO:0009123	85	0.015
male gonad development	GO:0008584	88	0.015
multicellular organismal signaling	GO:0035637	91	0.015
datp metabolic process	GO:0046060	2	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.015
modification dependent protein catabolic process	GO:0019941	133	0.015
alcohol biosynthetic process	GO:0046165	43	0.015
ribonucleoside monophosphate biosynthetic process	GO:0009156	9	0.015
neuronal action potential	GO:0019228	54	0.015
substantia nigra development	GO:0021762	2	0.015
leukocyte differentiation	GO:0002521	342	0.014
gtp metabolic process	GO:0046039	144	0.014
t cell differentiation	GO:0030217	174	0.014
iron sulfur cluster assembly	GO:0016226	3	0.014
regulation of cell activation	GO:0050865	289	0.014
positive regulation of growth	GO:0045927	104	0.014
organelle fusion	GO:0048284	28	0.014
regulation of proteolysis	GO:0030162	164	0.014
negative regulation of mitochondrion organization	GO:0010823	9	0.014
apoptotic signaling pathway	GO:0097190	306	0.014
energy derivation by oxidation of organic compounds	GO:0015980	77	0.014
mitochondrial dna replication	GO:0006264	7	0.013
regulation of t cell activation	GO:0050863	170	0.013
cellular response to molecule of bacterial origin	GO:0071219	83	0.013
positive regulation of protein kinase activity	GO:0045860	144	0.013
inorganic ion transmembrane transport	GO:0098660	234	0.013
positive regulation of ossification	GO:0045778	47	0.013
membrane fusion	GO:0061025	38	0.013
liver development	GO:0001889	66	0.013
cell type specific apoptotic process	GO:0097285	268	0.013
blood coagulation	GO:0007596	76	0.013
endomembrane system organization	GO:0010256	147	0.013
positive regulation of secretion	GO:0051047	130	0.013
protein targeting	GO:0006605	143	0.012
regulation of neuron differentiation	GO:0045664	281	0.012
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GO:1901028	7	0.012
negative regulation of protein maturation	GO:1903318	79	0.012
defense response to other organism	GO:0098542	197	0.012
regulation of mitochondrial membrane permeability	GO:0046902	17	0.012
negative regulation of proteolysis	GO:0045861	74	0.012
divalent metal ion transport	GO:0070838	172	0.012
positive regulation of leukocyte proliferation	GO:0070665	73	0.012
microtubule based process	GO:0007017	236	0.012
regulation of protein localization	GO:0032880	231	0.012
regulation of bone mineralization	GO:0030500	31	0.011
alcohol metabolic process	GO:0006066	116	0.011
response to lipopolysaccharide	GO:0032496	128	0.011
epithelial cell development	GO:0002064	159	0.011
fatty acid biosynthetic process	GO:0006633	41	0.011
hydrogen transport	GO:0006818	35	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
metallo sulfur cluster assembly	GO:0031163	3	0.011
leukocyte proliferation	GO:0070661	172	0.011
negative regulation of cellular amine metabolic process	GO:0033239	1	0.011
nitrogen compound transport	GO:0071705	271	0.011
coenzyme a metabolic process	GO:0015936	8	0.011
response to peptide	GO:1901652	136	0.011
regulation of cytokine production	GO:0001817	266	0.011
placenta development	GO:0001890	140	0.011
sequestering of metal ion	GO:0051238	19	0.011
protein localization to membrane	GO:0072657	108	0.011
positive regulation of cellular amine metabolic process	GO:0033240	5	0.011
female gamete generation	GO:0007292	74	0.011
cytokine production	GO:0001816	319	0.011
phospholipid metabolic process	GO:0006644	87	0.010
cellular ion homeostasis	GO:0006873	165	0.010
lipid localization	GO:0010876	126	0.010
retinoid metabolic process	GO:0001523	24	0.010
cellular response to decreased oxygen levels	GO:0036294	18	0.010
regulation of body fluid levels	GO:0050878	162	0.010
nadh metabolic process	GO:0006734	1	0.010
cellular calcium ion homeostasis	GO:0006874	119	0.010
organic hydroxy compound biosynthetic process	GO:1901617	77	0.010
regulation of vacuole organization	GO:0044088	4	0.010
neuron apoptotic process	GO:0051402	142	0.010
glycogen metabolic process	GO:0005977	32	0.010
pyruvate transport	GO:0006848	2	0.010
defense response to bacterium	GO:0042742	119	0.010

Echs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.868
inherited metabolic disorder	DOID:655	0.563
amino acid metabolic disorder	DOID:9252	0.563
disease of cellular proliferation	DOID:14566	0.047
gastrointestinal system cancer	DOID:3119	0.036
organ system cancer	DOID:0050686	0.036
cancer	DOID:162	0.036
endocrine gland cancer	DOID:170	0.016
organic acidemia	DOID:0060159	0.014

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