IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Gria4

glutamate receptor, ionotropic, AMPA4 (alpha 4)

(Aliases: GluA4,spkw1,Gluralpha4,Glur4,Glur-4,GluR-D)

Ensembl: ENSMUSG00000025892
Entrez: 14802
UniProtKB: E9PX01
UniProtKB: Q9Z2W8
UniProtKB: Q8C069

Process Predictions
Disease Predictions

Gria4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
synaptic transmission	GO:0007268	329	0.976	Mouse Rat Worm
negative regulation of synaptic transmission glutamatergic	GO:0051967	4	0.939	Mouse
ion transmembrane transport	GO:0034220	361	0.916	Human Mouse Rat Worm
adult behavior	GO:0030534	135	0.878
neuron neuron synaptic transmission	GO:0007270	69	0.855	Mouse Rat Worm
synaptic transmission glutamatergic	GO:0035249	36	0.847	Mouse Rat Worm
transmission of nerve impulse	GO:0019226	76	0.814	Mouse
membrane hyperpolarization	GO:0060081	21	0.798	Mouse
action potential	GO:0001508	78	0.773	Mouse
neuronal action potential	GO:0019228	54	0.735	Mouse
telencephalon cell migration	GO:0022029	55	0.701
nerve development	GO:0021675	67	0.688
fear response	GO:0042596	33	0.631	Mouse
regulation of neuron apoptotic process	GO:0043523	122	0.628	Mouse
multicellular organismal signaling	GO:0035637	91	0.620	Mouse
negative regulation of neuron death	GO:1901215	98	0.507	Mouse
regulation of neuronal synaptic plasticity	GO:0048168	30	0.496	Mouse
transmembrane transport	GO:0055085	412	0.487	Human Mouse Rat Worm
sensory perception	GO:0007600	245	0.484	Worm
reflex	GO:0060004	22	0.478
inorganic ion transmembrane transport	GO:0098660	234	0.455
cellular response to ammonium ion	GO:0071242	2	0.449
axonogenesis	GO:0007409	274	0.443
cerebellum development	GO:0021549	77	0.443
regulation of membrane potential	GO:0042391	192	0.443	Mouse
adult locomotory behavior	GO:0008344	91	0.423
regulation of postsynaptic membrane potential	GO:0060078	48	0.417	Mouse
regulation of response to drug	GO:2001023	2	0.393
ear development	GO:0043583	200	0.384
regulation of cellular component size	GO:0032535	121	0.353
intracellular protein transport	GO:0006886	204	0.349	Mouse
memory	GO:0007613	58	0.347	Mouse Worm
bronchiole morphogenesis	GO:0060436	1	0.342
oligodendrocyte development	GO:0014003	20	0.339
establishment of organelle localization	GO:0051656	122	0.338
microtubule based process	GO:0007017	236	0.337
inorganic cation transmembrane transport	GO:0098662	207	0.335
establishment of glial blood brain barrier	GO:0060857	2	0.333
sa node cell action potential	GO:0086015	4	0.325
locomotory behavior	GO:0007626	195	0.322
neuron projection extension	GO:1990138	64	0.317
regulation of long term neuronal synaptic plasticity	GO:0048169	19	0.302	Mouse
establishment of neuroblast polarity	GO:0045200	1	0.296
directional locomotion	GO:0033058	3	0.294	Worm
regulation of synaptic plasticity	GO:0048167	87	0.285	Mouse
microtubule cytoskeleton organization	GO:0000226	157	0.284
skeletal system morphogenesis	GO:0048705	203	0.277
negative regulation of neuron apoptotic process	GO:0043524	92	0.275	Mouse
synaptic transmission glycinergic	GO:0060012	2	0.268
learning or memory	GO:0007611	148	0.267	Mouse Worm
sensory perception of mechanical stimulus	GO:0050954	107	0.266
forebrain development	GO:0030900	302	0.263
neurotransmitter secretion	GO:0007269	62	0.263
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.262
sensory perception of chemical stimulus	GO:0007606	51	0.251	Worm
neuron apoptotic process	GO:0051402	142	0.248	Mouse
visual perception	GO:0007601	52	0.243
embryonic organ morphogenesis	GO:0048562	276	0.242
cell cell signaling involved in lung development	GO:0060495	1	0.237
cation transport	GO:0006812	399	0.234
telencephalon development	GO:0021537	186	0.234
regulation of respiratory system process	GO:0044065	13	0.234
regulation of voltage gated calcium channel activity	GO:1901385	4	0.232
embryonic skeletal system development	GO:0048706	120	0.230
regulation of neuron projection development	GO:0010975	169	0.227
nerve maturation	GO:0021682	1	0.226
regulation of ion transport	GO:0043269	215	0.219
regulation of neuron differentiation	GO:0045664	281	0.219
sensory perception of sound	GO:0007605	97	0.218
positive regulation of high voltage gated calcium channel activity	GO:1901843	1	0.213
membrane organization	GO:0061024	245	0.211
calcium ion transmembrane transport	GO:0070588	85	0.207
sodium ion transport	GO:0006814	73	0.207
regulation of neurotransmitter levels	GO:0001505	87	0.206
cation transmembrane transport	GO:0098655	266	0.205
regulation of ion transmembrane transport	GO:0034765	119	0.205
protein localization to juxtaparanode region of axon	GO:0071205	4	0.201
sensory perception of taste	GO:0050909	18	0.200	Worm
ear morphogenesis	GO:0042471	118	0.195
negative regulation of microtubule polymerization or depolymerization	GO:0031111	15	0.191
axon ensheathment	GO:0008366	76	0.189
regulation of synaptic transmission glutamatergic	GO:0051966	19	0.189	Mouse Rat
exocytosis	GO:0006887	121	0.189
forebrain cell migration	GO:0021885	58	0.186
regulation of neuron death	GO:1901214	134	0.184	Mouse
regulation of inhibitory postsynaptic membrane potential	GO:0060080	13	0.183	Mouse
regulation of anatomical structure size	GO:0090066	178	0.183
stem cell differentiation	GO:0048863	268	0.180
response to histamine	GO:0034776	1	0.178
glutamate receptor signaling pathway	GO:0007215	35	0.176	Human Mouse Rat Worm
forebrain neuron differentiation	GO:0021879	52	0.174
metal ion homeostasis	GO:0055065	189	0.173	Mouse
negative regulation of nervous system development	GO:0051961	156	0.171
endocytosis	GO:0006897	168	0.171	Mouse
camera type eye development	GO:0043010	266	0.164
nitrogen compound transport	GO:0071705	271	0.163
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.162
female genitalia morphogenesis	GO:0048807	3	0.162
neuron migration	GO:0001764	122	0.158
diencephalon development	GO:0021536	63	0.157
adult walking behavior	GO:0007628	41	0.156
cellular response to histamine	GO:0071420	1	0.156
myelination	GO:0042552	74	0.155
cellular ion homeostasis	GO:0006873	165	0.152	Mouse
response to radiation	GO:0009314	165	0.151
negative regulation of neuron differentiation	GO:0045665	101	0.150
neuron death	GO:0070997	154	0.148	Mouse
asymmetric neuroblast division	GO:0055059	1	0.146
acetylcholine transport	GO:0015870	2	0.145
substrate independent telencephalic tangential migration	GO:0021826	8	0.145
regulation of protein depolymerization	GO:1901879	26	0.145
sensory perception of light stimulus	GO:0050953	54	0.143
mesenchyme development	GO:0060485	152	0.141
conditioned taste aversion	GO:0001661	4	0.141
rhodopsin mediated signaling pathway	GO:0016056	4	0.137
anatomical structure arrangement	GO:0048532	20	0.137
male anatomical structure morphogenesis	GO:0090598	4	0.135
regulation of metal ion transport	GO:0010959	106	0.135
cell type specific apoptotic process	GO:0097285	268	0.134	Mouse
protein polymerization	GO:0051258	57	0.133
cellular protein complex assembly	GO:0043623	116	0.130
ensheathment of neurons	GO:0007272	76	0.129
protein complex disassembly	GO:0043241	40	0.129
regulation of sodium ion transport	GO:0002028	29	0.128
microtubule polymerization or depolymerization	GO:0031109	26	0.128
multicellular organism growth	GO:0035264	161	0.124
negative regulation of protein depolymerization	GO:1901880	21	0.123
purine ribonucleotide metabolic process	GO:0009150	290	0.122
cell adhesion	GO:0007155	329	0.120
regulation of ion transmembrane transporter activity	GO:0032412	54	0.120
regulation of white fat cell proliferation	GO:0070350	2	0.117
cellular chemical homeostasis	GO:0055082	215	0.116	Mouse
establishment of protein localization to organelle	GO:0072594	118	0.115
cognition	GO:0050890	149	0.115	Mouse Worm
forebrain neuron development	GO:0021884	30	0.115
response to light stimulus	GO:0009416	135	0.114
cellular metal ion homeostasis	GO:0006875	151	0.114	Mouse
gland development	GO:0048732	330	0.114
glial cell development	GO:0021782	54	0.114
multicellular organismal response to stress	GO:0033555	62	0.113	Mouse
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.112
neuromuscular process	GO:0050905	99	0.112
positive regulation of neuron projection development	GO:0010976	79	0.111
small gtpase mediated signal transduction	GO:0007264	97	0.111
metencephalon development	GO:0022037	89	0.111
learning	GO:0007612	98	0.110
positive regulation of fat cell proliferation	GO:0070346	1	0.110
regulation of organelle organization	GO:0033043	289	0.109
negative regulation of protein complex disassembly	GO:0043242	22	0.108
sensory perception of bitter taste	GO:0050913	6	0.108	Worm
organelle localization	GO:0051640	179	0.108
lung proximal distal axis specification	GO:0061115	1	0.106
axon guidance	GO:0007411	141	0.106
regulation of high voltage gated calcium channel activity	GO:1901841	2	0.105
positive regulation of nervous system development	GO:0051962	221	0.104
regulation of cell size	GO:0008361	72	0.104
ribonucleotide catabolic process	GO:0009261	208	0.103
neuron projection guidance	GO:0097485	141	0.103
positive regulation of adenosine receptor signaling pathway	GO:0060168	1	0.102
lung pattern specification process	GO:0060432	1	0.102
receptor internalization	GO:0031623	16	0.102	Mouse
cranial nerve development	GO:0021545	41	0.101
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.099
cerebral cortex development	GO:0021987	86	0.099
stem cell development	GO:0048864	219	0.099
potassium ion homeostasis	GO:0055075	4	0.097
inner ear receptor cell differentiation	GO:0060113	61	0.096
asymmetric stem cell division	GO:0098722	3	0.096
smoothened signaling pathway	GO:0007224	105	0.094
protein localization to membrane	GO:0072657	108	0.093
establishment of vesicle localization	GO:0051650	81	0.093
male courtship behavior	GO:0008049	2	0.093
vesicle localization	GO:0051648	86	0.093
positive regulation of sodium ion transport	GO:0010765	13	0.091
behavioral fear response	GO:0001662	28	0.091	Mouse
bone morphogenesis	GO:0060349	78	0.090
cell division	GO:0051301	120	0.090
mesenchymal epithelial cell signaling involved in lung development	GO:0060496	1	0.089
regulation of axon extension	GO:0030516	43	0.089
nuclear transport	GO:0051169	139	0.088
white fat cell proliferation	GO:0070343	2	0.088
regulation of cell cycle	GO:0051726	281	0.087
oligodendrocyte differentiation	GO:0048709	53	0.087
long term synaptic depression	GO:0060292	13	0.086	Mouse
protein targeting	GO:0006605	143	0.084
regulation of short term neuronal synaptic plasticity	GO:0048172	8	0.084	Mouse
dendrite development	GO:0016358	115	0.084
synaptic vesicle transport	GO:0048489	57	0.083
cochlea development	GO:0090102	35	0.083
mechanoreceptor differentiation	GO:0042490	67	0.081
synaptic vesicle localization	GO:0097479	59	0.080
central nervous system myelination	GO:0022010	12	0.080
developmental growth involved in morphogenesis	GO:0060560	138	0.079
regulation of protein complex disassembly	GO:0043244	28	0.079
mesenchymal cell differentiation	GO:0048762	107	0.078
spleen development	GO:0048536	39	0.076
regulation of cell projection organization	GO:0031344	206	0.076
central nervous system neuron differentiation	GO:0021953	162	0.076
response to organic cyclic compound	GO:0014070	198	0.076
cerebral cortex neuron differentiation	GO:0021895	19	0.076
kidney development	GO:0001822	213	0.075
regulation of secretion by cell	GO:1903530	249	0.075
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.075
male sex differentiation	GO:0046661	109	0.075
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.075
cation homeostasis	GO:0055080	212	0.075	Mouse
calcium ion dependent exocytosis	GO:0017156	35	0.074
gtp metabolic process	GO:0046039	144	0.074
hindbrain development	GO:0030902	128	0.073
positive regulation of neuron differentiation	GO:0045666	141	0.073
receptor mediated endocytosis	GO:0006898	51	0.072	Mouse
forebrain generation of neurons	GO:0021872	63	0.072
positive regulation of growth	GO:0045927	104	0.072
protein import into nucleus	GO:0006606	95	0.071
sensory organ morphogenesis	GO:0090596	242	0.071
semicircular canal fusion	GO:0060879	1	0.070
defecation	GO:0030421	1	0.070
development of primary sexual characteristics	GO:0045137	143	0.070
neurotransmitter transport	GO:0006836	76	0.070
purine nucleotide metabolic process	GO:0006163	302	0.069
endomembrane system organization	GO:0010256	147	0.069
response to ammonium ion	GO:0060359	21	0.068
optic nerve structural organization	GO:0021633	2	0.067
negative regulation of cell development	GO:0010721	169	0.067
cellular calcium ion homeostasis	GO:0006874	119	0.067	Mouse
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.067
macromolecular complex disassembly	GO:0032984	43	0.066
positive regulation of transferase activity	GO:0051347	167	0.065
female sex differentiation	GO:0046660	84	0.065
regulation of microtubule based process	GO:0032886	52	0.065
nuclear import	GO:0051170	95	0.065
gonad development	GO:0008406	141	0.064
nucleoside metabolic process	GO:0009116	246	0.064
purine nucleotide catabolic process	GO:0006195	211	0.064
cellular amino acid metabolic process	GO:0006520	103	0.064
glial cell differentiation	GO:0010001	131	0.063
purine containing compound metabolic process	GO:0072521	311	0.063
chloride transmembrane transport	GO:1902476	24	0.063
divalent inorganic cation transport	GO:0072511	178	0.062
regulation of extent of cell growth	GO:0061387	52	0.062
limbic system development	GO:0021761	72	0.062
cell proliferation in external granule layer	GO:0021924	10	0.062
sa node cell to atrial cardiac muscle cell signalling	GO:0086018	4	0.061
membrane depolarization	GO:0051899	64	0.061	Mouse
submandibular salivary gland formation	GO:0060661	1	0.061
nucleocytoplasmic transport	GO:0006913	139	0.061
protein depolymerization	GO:0051261	34	0.061
positive regulation of map kinase activity	GO:0043406	84	0.060
mitotic cell cycle	GO:0000278	195	0.060
embryonic camera type eye development	GO:0031076	36	0.060
ribose phosphate metabolic process	GO:0019693	291	0.059
neuron maturation	GO:0042551	29	0.059
positive regulation of apoptotic process	GO:0043065	217	0.059
limb morphogenesis	GO:0035108	149	0.058
fertilization	GO:0009566	127	0.058
anatomical structure homeostasis	GO:0060249	145	0.058
male gamete generation	GO:0048232	285	0.058
apoptotic signaling pathway	GO:0097190	306	0.058
protein maturation	GO:0051604	176	0.058
plasma membrane organization	GO:0007009	90	0.057
genitalia morphogenesis	GO:0035112	11	0.057
ribonucleoside metabolic process	GO:0009119	245	0.057
cerebral cortex gabaergic interneuron development	GO:0021894	6	0.057
lateral line system development	GO:0048925	1	0.056
central nervous system maturation	GO:0021626	6	0.056
single organism nuclear import	GO:1902593	95	0.056
amino acid transport	GO:0006865	61	0.056
male genitalia morphogenesis	GO:0048808	4	0.055
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.055	Mouse
regulation of system process	GO:0044057	200	0.055
response to organonitrogen compound	GO:0010243	246	0.055
calcium ion homeostasis	GO:0055074	127	0.054	Mouse
hyperosmotic response	GO:0006972	4	0.054	Worm
axonal fasciculation	GO:0007413	15	0.053
organ growth	GO:0035265	117	0.053
negative regulation of cellular component organization	GO:0051129	194	0.053
meiotic cell cycle	GO:0051321	122	0.053
protein import	GO:0017038	101	0.053
glycosyl compound catabolic process	GO:1901658	206	0.053
regulation of circadian sleep wake cycle	GO:0042749	3	0.053
regulation of axon diameter	GO:0031133	6	0.052
embryonic limb morphogenesis	GO:0030326	126	0.052
terminal button organization	GO:0072553	3	0.052
protein localization to organelle	GO:0033365	185	0.051
establishment of synaptic vesicle localization	GO:0097480	57	0.051
regulation of feeding behavior	GO:0060259	3	0.051
regulation of action potential	GO:0098900	4	0.051
respiratory system development	GO:0060541	190	0.051
protein localization to nucleus	GO:0034504	121	0.051
developmental maturation	GO:0021700	193	0.051
response to fibroblast growth factor	GO:0071774	47	0.050
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.050	Mouse
regulation of protein transport	GO:0051223	163	0.050
regulation of fibroblast proliferation	GO:0048145	34	0.050
respiratory tube development	GO:0030323	167	0.050
mapk cascade	GO:0000165	281	0.050
cerebral cortex cell migration	GO:0021795	44	0.049
fat cell proliferation	GO:0070341	4	0.049
cytoplasmic transport	GO:0016482	234	0.049
regulation of protein kinase activity	GO:0045859	232	0.048
acrosome reaction	GO:0007340	19	0.048
germ cell development	GO:0007281	185	0.048
regulation of smoothened signaling pathway	GO:0008589	58	0.048
clustering of voltage gated potassium channels	GO:0045163	2	0.048
cellular protein complex disassembly	GO:0043624	36	0.048
inner ear receptor cell development	GO:0060119	39	0.048
mammary gland bud formation	GO:0060615	2	0.047
ventral trunk neural crest cell migration	GO:0036486	4	0.047
stem cell maintenance	GO:0019827	130	0.047
divalent inorganic cation homeostasis	GO:0072507	138	0.047	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.046
microtubule depolymerization	GO:0007019	15	0.046
cellular response to organonitrogen compound	GO:0071417	145	0.046
microtubule based movement	GO:0007018	84	0.046
central nervous system neuron development	GO:0021954	67	0.046
regulation of g protein activated inward rectifier potassium channel activity	GO:1900128	1	0.046
neuron projection extension involved in neuron projection guidance	GO:1902284	14	0.046
regulation of microtubule polymerization or depolymerization	GO:0031110	20	0.045
cerebellar granule cell precursor proliferation	GO:0021930	10	0.045
aromatic compound catabolic process	GO:0019439	286	0.045
single fertilization	GO:0007338	82	0.045
gamma aminobutyric acid signaling pathway	GO:0007214	8	0.045
cellular ketone metabolic process	GO:0042180	84	0.044
purine ribonucleoside metabolic process	GO:0046128	241	0.044
compound eye development	GO:0048749	1	0.044
purine containing compound catabolic process	GO:0072523	213	0.044
spermatogenesis	GO:0007283	284	0.044
cell growth	GO:0016049	130	0.044
regulation of respiratory gaseous exchange by neurological system process	GO:0002087	12	0.043
purine nucleoside catabolic process	GO:0006152	205	0.043
striated muscle tissue development	GO:0014706	293	0.043
l amino acid transport	GO:0015807	32	0.043
ras protein signal transduction	GO:0007265	77	0.042
nucleobase containing small molecule metabolic process	GO:0055086	352	0.042
corticotropin hormone secreting cell differentiation	GO:0060128	3	0.042
palate development	GO:0060021	76	0.042
g protein coupled receptor signaling pathway	GO:0007186	243	0.042
ribonucleoside catabolic process	GO:0042454	206	0.042
nucleotide metabolic process	GO:0009117	332	0.042
cell proliferation in hindbrain	GO:0021534	10	0.041
embryonic genitalia morphogenesis	GO:0030538	4	0.041
positive regulation of white fat cell proliferation	GO:0070352	1	0.041
endocrine system development	GO:0035270	98	0.041
cellular homeostasis	GO:0019725	240	0.041	Mouse
skeletal system development	GO:0001501	356	0.041
detection of abiotic stimulus	GO:0009582	60	0.040
anion transport	GO:0006820	177	0.040
developmental cell growth	GO:0048588	84	0.040
harderian gland development	GO:0070384	2	0.040
lung development	GO:0030324	164	0.040
regulation of axon guidance	GO:1902667	13	0.040
mammary gland specification	GO:0060594	4	0.040
phosphatidylinositol metabolic process	GO:0046488	45	0.040
positive regulation of necrotic cell death	GO:0010940	1	0.040
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.039
cerebral cortex gabaergic interneuron differentiation	GO:0021892	9	0.039
regulation of neurotransmitter secretion	GO:0046928	29	0.039
macromolecule catabolic process	GO:0009057	281	0.039
anion transmembrane transport	GO:0098656	71	0.039
cardiac cell fate specification	GO:0060912	2	0.039
nucleoside triphosphate catabolic process	GO:0009143	205	0.039
cellular response to fibroblast growth factor stimulus	GO:0044344	47	0.038
cerebral cortex tangential migration using cell axon interactions	GO:0021824	3	0.038
visual behavior	GO:0007632	45	0.038
fibroblast proliferation	GO:0048144	35	0.038
righting reflex	GO:0060013	9	0.038
regulation of cell growth	GO:0001558	91	0.038
cerebral cortex gabaergic interneuron migration	GO:0021853	6	0.037
regulation of exocytosis	GO:0017157	61	0.037
spermatid differentiation	GO:0048515	115	0.037
negative regulation of cell proliferation	GO:0008285	296	0.037
mesenchymal cell development	GO:0014031	93	0.037
peptide hormone secretion	GO:0030072	109	0.037
regulation of cytoskeleton organization	GO:0051493	122	0.037
regulation of transmembrane transport	GO:0034762	128	0.037
nucleotide catabolic process	GO:0009166	217	0.037
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.037
regulation of tube size	GO:0035150	57	0.037
ribonucleotide metabolic process	GO:0009259	291	0.037
neuron recognition	GO:0008038	25	0.037
muscle tissue development	GO:0060537	308	0.036
actin filament polymerization	GO:0030041	44	0.036
appendage morphogenesis	GO:0035107	149	0.036
digestive tract development	GO:0048565	190	0.036
regulation of fat cell proliferation	GO:0070344	4	0.035
embryonic appendage morphogenesis	GO:0035113	126	0.035
glutamine family amino acid biosynthetic process	GO:0009084	2	0.035
gliogenesis	GO:0042063	141	0.035
regulation of protein maturation	GO:1903317	96	0.035
synaptic vesicle recycling	GO:0036465	19	0.035
divalent metal ion transport	GO:0070838	172	0.035
regulation of adenosine receptor signaling pathway	GO:0060167	1	0.035
positive regulation of activin receptor signaling pathway	GO:0032927	3	0.034
fast calcium ion dependent exocytosis of neurotransmitter	GO:0098746	1	0.034
regulation of cell migration	GO:0030334	219	0.034
cranial nerve morphogenesis	GO:0021602	26	0.034
limb development	GO:0060173	166	0.034
positive regulation of axon extension	GO:0045773	20	0.034
regulation of cell motility	GO:2000145	236	0.034
positive regulation of kinase activity	GO:0033674	155	0.034
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.034
inner ear morphogenesis	GO:0042472	101	0.034
cell cell junction organization	GO:0045216	72	0.033
striated muscle cell proliferation	GO:0014855	39	0.033
neural nucleus development	GO:0048857	22	0.033
glycerophospholipid metabolic process	GO:0006650	71	0.033
protein oligomerization	GO:0051259	67	0.033
membrane depolarization during sa node cell action potential	GO:0086046	2	0.033
male sex determination	GO:0030238	14	0.033
heart process	GO:0003015	94	0.033
regulation of microtubule cytoskeleton organization	GO:0070507	37	0.033
regulation of cation channel activity	GO:2001257	22	0.033
positive regulation of protein modification process	GO:0031401	299	0.033
tube closure	GO:0060606	91	0.033
regulation of mapk cascade	GO:0043408	248	0.033
spermatid development	GO:0007286	108	0.032
establishment of mitotic spindle localization	GO:0040001	12	0.032
regulation of cellular ketone metabolic process	GO:0010565	66	0.032
spinal cord development	GO:0021510	81	0.032
urogenital system development	GO:0001655	261	0.032
purine ribonucleotide catabolic process	GO:0009154	208	0.032
regulation of hormone secretion	GO:0046883	88	0.032
synapse organization	GO:0050808	125	0.032
neural crest cell migration involved in autonomic nervous system development	GO:1901166	5	0.032
preganglionic parasympathetic nervous system development	GO:0021783	17	0.032
detection of stimulus	GO:0051606	84	0.032
negative regulation of neuron projection development	GO:0010977	50	0.032
stem cell proliferation	GO:0072089	117	0.031
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.031
regulation of ossification	GO:0030278	112	0.031
epithelial tube morphogenesis	GO:0060562	303	0.031
fibroblast growth factor receptor signaling pathway	GO:0008543	46	0.031
positive regulation of cell death	GO:0010942	224	0.031
detection of external stimulus	GO:0009581	61	0.031
neural crest cell development	GO:0014032	48	0.031
actin cytoskeleton organization	GO:0030036	220	0.031
negative regulation of organelle organization	GO:0010639	90	0.031
positive regulation of defense response	GO:0031349	124	0.030
negative regulation of growth	GO:0045926	99	0.030
courtship behavior	GO:0007619	5	0.030
cellular potassium ion transport	GO:0071804	43	0.030
retinal ganglion cell axon guidance	GO:0031290	18	0.030
morphogenesis of embryonic epithelium	GO:0016331	159	0.030
regulation of transporter activity	GO:0032409	57	0.030
positive regulation of cellular amine metabolic process	GO:0033240	5	0.030
cilium morphogenesis	GO:0060271	102	0.030
substantia nigra development	GO:0021762	2	0.030
epithelial cell development	GO:0002064	159	0.030
cellular response to organic cyclic compound	GO:0071407	87	0.030
negative regulation of hormone metabolic process	GO:0032351	4	0.030
positive regulation of protein kinase activity	GO:0045860	144	0.029
lens development in camera type eye	GO:0002088	62	0.029
g protein coupled receptor internalization	GO:0002031	3	0.029
synaptic vesicle endocytosis	GO:0048488	19	0.029
activation of transmembrane receptor protein tyrosine kinase activity	GO:0007171	3	0.029
bronchiole development	GO:0060435	3	0.029
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.029
mating behavior sex discrimination	GO:0048047	1	0.029
regulation of nucleoside metabolic process	GO:0009118	130	0.029
pole plasm assembly	GO:0007315	2	0.029
gtp catabolic process	GO:0006184	143	0.028
protein processing	GO:0016485	163	0.028
organic acid transport	GO:0015849	101	0.028
regulation of respiratory gaseous exchange	GO:0043576	18	0.028
regulation of cellular catabolic process	GO:0031329	242	0.028
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.028
negative regulation of cytoskeleton organization	GO:0051494	36	0.028
erk1 and erk2 cascade	GO:0070371	77	0.028
digestive tract morphogenesis	GO:0048546	147	0.028
mesenchymal cell differentiation involved in lung development	GO:0060915	2	0.028
lipid modification	GO:0030258	65	0.028
digestive system development	GO:0055123	200	0.028
positive regulation of cell development	GO:0010720	237	0.028
regulation of reproductive process	GO:2000241	66	0.027
regulation of calcium ion transport	GO:0051924	69	0.027
rho protein signal transduction	GO:0007266	32	0.027
fat cell differentiation	GO:0045444	160	0.027
acetylcholine secretion neurotransmission	GO:0014055	2	0.027
tissue homeostasis	GO:0001894	115	0.027
morphogenesis of a branching structure	GO:0001763	203	0.027
regulation of timing of cell differentiation	GO:0048505	11	0.027
regulation of neurotransmitter transport	GO:0051588	35	0.027
pituitary gland development	GO:0021983	38	0.027
nucleoside phosphate catabolic process	GO:1901292	222	0.027
mitotic cell cycle process	GO:1903047	159	0.027
microtubule polymerization	GO:0046785	12	0.027
spindle localization	GO:0051653	22	0.026
organonitrogen compound catabolic process	GO:1901565	264	0.026
dephosphorylation	GO:0016311	129	0.026
toxin transport	GO:1901998	38	0.026
heterocycle catabolic process	GO:0046700	280	0.026
molting cycle	GO:0042303	90	0.026
regulation of calcium ion transmembrane transport	GO:1903169	20	0.026
bone development	GO:0060348	120	0.026

Gria4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of mental health	DOID:150	0.075
nervous system disease	DOID:863	0.045
disease of anatomical entity	DOID:7	0.045
sensory system disease	DOID:0050155	0.028
musculoskeletal system disease	DOID:17	0.027

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