Mus musculus

191 known processes

Foxo3

forkhead box O3

(Aliases: FKHRL1,2010203A17Rik,Fkhr2,1110048B16Rik,C76856,Foxo3a)

Foxo3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.773
dna metabolic processGO:00062593030.673
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.651
Fly
dna repairGO:00062811070.642
cellular response to starvationGO:0009267570.632
Fly
carbohydrate derivative biosynthetic processGO:19011371830.591
Fly
male gamete generationGO:00482322850.501
germ cell developmentGO:00072811850.440
embryonic organ morphogenesisGO:00485622760.401
regionalizationGO:00030023370.371
cyclic nucleotide metabolic processGO:0009187590.352
Fly
apoptotic signaling pathwayGO:00971903060.330
spermatid developmentGO:00072861080.329
regulation of cellular response to stressGO:00801351590.328
Fly
generation of precursor metabolites and energyGO:00060911030.324
Fly
negative regulation of cell cycleGO:00457861230.318
Mouse
negative regulation of mitotic cell cycleGO:0045930580.310
Mouse
negative regulation of cell proliferationGO:00082852960.292
Mouse Fly
regulation of histone methylationGO:0031060300.289
rhythmic processGO:00485111740.289
purine ribonucleotide metabolic processGO:00091502900.283
Fly
mitotic cell cycleGO:00002781950.283
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.267
cohesin localization to chromatinGO:007192110.266
female gonad developmentGO:0008585710.264
cell cycle arrestGO:0007050370.251
purine containing compound biosynthetic processGO:0072522700.245
Fly
cellular amino acid metabolic processGO:00065201030.232
limb morphogenesisGO:00351081490.227
nucleotide biosynthetic processGO:0009165780.224
Fly
regulation of mitotic cell cycleGO:00073461260.212
Mouse
embryonic skeletal system morphogenesisGO:0048704910.199
muscle tissue developmentGO:00605373080.198
Worm
response to nutrient levelsGO:00316671090.197
Fly
protein targetingGO:00066051430.196
stem cell developmentGO:00488642190.193
mitotic cell cycle processGO:19030471590.191
Mouse
antral ovarian follicle growthGO:000154750.186
cellular homeostasisGO:00197252400.184
stem cell maintenanceGO:00198271300.182
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.174
reactive oxygen species metabolic processGO:0072593840.173
canonical wnt signaling pathwayGO:00600701300.173
regulation of cell cycle phase transitionGO:1901987770.168
Mouse
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.165
positive regulation of apoptotic processGO:00430652170.165
Human Worm
cellular response to oxidative stressGO:0034599760.164
regulation of feeding behaviorGO:006025930.163
Fly
skeletal system developmentGO:00015013560.160
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.159
oocyte differentiationGO:0009994350.156
cellular response to nutrient levelsGO:0031669640.150
Fly
extrinsic apoptotic signaling pathwayGO:00971911260.150
regulation of cell cycleGO:00517262810.150
Mouse Worm
sperm individualizationGO:000729110.149
response to uvGO:0009411440.147
Worm
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.147
Fly
negative regulation of cell cycle phase transitionGO:1901988480.144
Mouse
cellular response to external stimulusGO:0071496880.144
Fly
regulation of reactive oxygen species metabolic processGO:2000377400.141
negative regulation of protein serine threonine kinase activityGO:0071901490.139
macroautophagyGO:0016236210.136
Fly
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.136
intra s dna damage checkpointGO:003157340.135
ovarian follicle developmentGO:0001541400.129
positive regulation of cell deathGO:00109422240.129
Human Worm
cellular response to extracellular stimulusGO:0031668810.127
Fly
histone lysine methylationGO:0034968500.125
lung developmentGO:00303241640.125
dna biosynthetic processGO:0071897220.125
sulfur compound biosynthetic processGO:0044272370.121
ribose phosphate metabolic processGO:00196932910.121
Fly
protein methylationGO:0006479810.120
embryonic skeletal system developmentGO:00487061200.120
mitotic cell cycle arrestGO:007185040.119
morphogenesis of a branching structureGO:00017632030.117
regulation of bindingGO:00510981110.116
embryonic limb morphogenesisGO:00303261260.115
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.113
response to oxygen levelsGO:0070482620.110
cellular amine metabolic processGO:0044106440.110
spermatogenesisGO:00072832840.109
regulation of protein kinase activityGO:00458592320.108
embryonic appendage morphogenesisGO:00351131260.107
response to organonitrogen compoundGO:00102432460.105
Mouse Worm Fly
sulfur compound metabolic processGO:00067901000.105
regulation of cohesin localization to chromatinGO:007192210.104
fat cell differentiationGO:00454441600.102
Mouse
purine nucleotide biosynthetic processGO:0006164650.101
Fly
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.101
regulation of autophagyGO:0010506300.101
Fly
camp biosynthetic processGO:0006171310.101
Fly
regulation of canonical wnt signaling pathwayGO:0060828820.100
macromolecule methylationGO:00434141200.100
establishment of protein localization to organelleGO:00725941180.100
response to extracellular stimulusGO:00099911270.100
Fly
carbohydrate metabolic processGO:00059752300.099
Mouse Fly
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.097
regulation of leukocyte differentiationGO:19021051590.097
development of primary female sexual characteristicsGO:0046545730.097
regulation of cell sizeGO:0008361720.096
Fly
regulation of protein serine threonine kinase activityGO:00719001570.095
response to light stimulusGO:00094161350.095
Worm
cellular macromolecule catabolic processGO:00442652060.094
glycoprotein biosynthetic processGO:0009101890.092
circulatory system processGO:00030131970.092
locomotory behaviorGO:00076261950.092
Fly
negative regulation of growthGO:0045926990.091
Worm Fly
g1 s transition of mitotic cell cycleGO:0000082570.090
double strand break repairGO:0006302480.090
spermatid differentiationGO:00485151150.089
respiratory system developmentGO:00605411900.085
oogenesisGO:0048477560.085
cell type specific apoptotic processGO:00972852680.085
Human Zebrafish
positive regulation of cellular amino acid metabolic processGO:004576430.085
autophagyGO:0006914450.085
Fly
carbohydrate homeostasisGO:00335001280.084
skeletal muscle organ developmentGO:00605381630.083
female sex differentiationGO:0046660840.082
proteoglycan biosynthetic processGO:0030166200.082
energy derivation by oxidation of organic compoundsGO:0015980770.082
Fly
regulation of macroautophagyGO:0016241120.082
Fly
ribose phosphate biosynthetic processGO:0046390590.082
Fly
embryonic viscerocranium morphogenesisGO:004870380.082
regulation of organelle organizationGO:00330432890.080
amine metabolic processGO:0009308450.080
negative regulation of protein metabolic processGO:00512482820.080
negative regulation of protein phosphorylationGO:00019331260.080
nucleotide excision repairGO:0006289130.080
sensory perception of soundGO:0007605970.079
blood circulationGO:00080151950.079
transforming growth factor beta receptor signaling pathwayGO:0007179710.078
negative regulation of leukocyte differentiationGO:1902106510.078
cell cycle g1 s phase transitionGO:0044843570.078
blastocyst developmentGO:0001824800.078
cellular response to transforming growth factor beta stimulusGO:0071560880.077
response to radiationGO:00093141650.077
Worm
glycoprotein metabolic processGO:00091001160.076
protein alkylationGO:0008213810.076
negative regulation of phosphorylationGO:00423261660.076
cation transportGO:00068123990.076
regulation of cellular ketone metabolic processGO:0010565660.075
Mouse
cellular response to peptide hormone stimulusGO:0071375920.075
Mouse Worm Fly
response to starvationGO:0042594650.075
Fly
response to peptideGO:19016521360.074
Mouse Worm Fly
mitotic g1 dna damage checkpointGO:003157140.074
sensory perceptionGO:00076002450.074
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.074
glial cell apoptotic processGO:003434930.073
regulation of androgen receptor signaling pathwayGO:006076530.072
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.072
response to oxidative stressGO:00069791230.071
cellular response to organic cyclic compoundGO:0071407870.071
positive regulation of kinase activityGO:00336741550.071
carbohydrate biosynthetic processGO:0016051740.071
Mouse
lymphocyte differentiationGO:00300982420.070
positive regulation of ion transportGO:0043270650.070
multicellular organismal homeostasisGO:00488711640.069
gene silencingGO:0016458380.069
maintenance of locationGO:0051235890.069
Fly
purine ribonucleotide biosynthetic processGO:0009152590.069
Fly
peptidyl amino acid modificationGO:00181933360.069
signal transduction by p53 class mediatorGO:0072331510.069
double strand break repair via homologous recombinationGO:0000724210.069
positive regulation of bindingGO:0051099490.068
negative regulation of protein modification processGO:00314001630.068
methylationGO:00322591340.068
organonitrogen compound biosynthetic processGO:19015661920.068
Fly
somite developmentGO:0061053810.067
cellular protein catabolic processGO:00442571550.067
t cell activationGO:00421102890.067
regulation of activin receptor signaling pathwayGO:0032925100.066
Fly
cyclic nucleotide biosynthetic processGO:0009190440.066
Fly
regulation of cellular amino acid metabolic processGO:000652150.065
cognitionGO:00508901490.064
protein localization to chromatinGO:007116830.064
epithelial cell proliferationGO:00506731740.063
camp metabolic processGO:0046058400.062
Fly
cellularizationGO:000734910.062
positive regulation of apoptotic signaling pathwayGO:2001235950.061
regulation of intracellular transportGO:00323861590.061
regulation of transferase activityGO:00513382630.061
i kappab kinase nf kappab signalingGO:0007249850.060
regulation of apoptotic signaling pathwayGO:20012331970.060
positive regulation of proteolysisGO:0045862850.060
protein modification by small protein conjugationGO:00324461870.060
connective tissue developmentGO:00614481790.059
blood vessel morphogenesisGO:00485142850.059
regulation of system processGO:00440572000.059
regulation of anatomical structure sizeGO:00900661780.058
Fly
dna recombinationGO:0006310920.058
negative regulation of molecular functionGO:00440922580.057
regulation of neuron deathGO:19012141340.057
Human Zebrafish
protein catabolic processGO:00301632210.057
adaptive immune responseGO:00022501550.057
Worm
respiratory tube developmentGO:00303231670.056
learningGO:0007612980.056
fatty acid biosynthetic processGO:0006633410.056
response to peptide hormoneGO:00434341270.056
Mouse Worm Fly
learning or memoryGO:00076111480.056
regulation of cellular amine metabolic processGO:0033238200.055
cellular ketone metabolic processGO:0042180840.055
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.055
regulation of neural precursor cell proliferationGO:2000177700.055
regulation of glucose metabolic processGO:0010906600.054
Mouse
response to acid chemicalGO:00011011110.054
cell adhesionGO:00071553290.054
signal transduction in absence of ligandGO:0038034550.054
stem cell differentiationGO:00488632680.054
neural precursor cell proliferationGO:00613511210.053
response to organic cyclic compoundGO:00140701980.053
chondrocyte differentiationGO:0002062720.053
regulation of hydrolase activityGO:00513362460.052
regulation of cell growthGO:0001558910.052
Fly
organophosphate biosynthetic processGO:00904071220.052
Fly
activin receptor signaling pathwayGO:0032924180.052
Fly
heart morphogenesisGO:00030071780.051
b cell activationGO:00421131610.051
cellular carbohydrate metabolic processGO:00442621190.051
Mouse Fly
negative regulation of cell cycle processGO:0010948690.051
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.050
positive regulation of protein modification processGO:00314012990.050
positive regulation of transferase activityGO:00513471670.050
recombinational repairGO:0000725210.050
cell agingGO:0007569350.049
multicellular organismal agingGO:0010259240.049
Worm Fly
limb developmentGO:00601731660.049
cellular response to growth factor stimulusGO:00713631970.049
organ growthGO:00352651170.048
g protein coupled receptor signaling pathwayGO:00071862430.048
Fly
microtubule based processGO:00070172360.048
Fly
ear developmentGO:00435832000.047
negative regulation of transferase activityGO:0051348850.047
ossificationGO:00015032160.047
mitotic cell cycle checkpointGO:0007093310.047
Mouse
striated muscle tissue developmentGO:00147062930.047
response to drugGO:0042493750.047
cyclic purine nucleotide metabolic processGO:0052652430.047
Fly
cellular response to lipidGO:00713961450.047
epithelial tube morphogenesisGO:00605623030.047
response to reactive oxygen speciesGO:0000302560.047
Mouse
steroid metabolic processGO:00082021190.046
protein modification by small protein conjugation or removalGO:00706472070.046
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.046
Mouse Worm Fly
cellular response to steroid hormone stimulusGO:0071383330.046
oocyte axis specificationGO:000730920.046
response to hypoxiaGO:0001666580.045
regulation of kinase activityGO:00435492490.045
palate developmentGO:0060021760.044
appendage developmentGO:00487361660.044
Fly
regulation of lipid metabolic processGO:00192161180.044
Worm Fly
regulation of reproductive processGO:2000241660.044
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.043
purine nucleotide metabolic processGO:00061633020.043
Fly
dna damage checkpointGO:0000077260.043
Mouse
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.042
regulation of chromatin silencingGO:003193520.042
histone methylationGO:0016571710.042
dna damage response signal transduction by p53 class mediatorGO:0030330190.041
ribonucleoside metabolic processGO:00091192450.041
proteoglycan metabolic processGO:0006029380.041
hexose biosynthetic processGO:0019319390.041
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.041
nucleotide metabolic processGO:00091173320.041
Fly
negative regulation of kinase activityGO:0033673810.041
protein glycosylationGO:0006486550.041
mitotic sister chromatid cohesionGO:000706410.041
regulation of protein import into nucleus translocationGO:003315820.041
protein localization to membraneGO:00726571080.040
regulation of bmp signaling pathwayGO:0030510600.040
myeloid leukocyte differentiationGO:00025731190.040
response to inorganic substanceGO:0010035960.040
Mouse
response to steroid hormoneGO:0048545560.039
positive regulation of cellular protein catabolic processGO:1903364340.039
immature b cell differentiationGO:0002327100.039
response to insulinGO:00328681000.039
Mouse Worm Fly
nucleocytoplasmic transportGO:00069131390.039
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.038
regulation of blood pressureGO:0008217930.038
monocarboxylic acid metabolic processGO:00327871910.038
regulation of protein catabolic processGO:00421761080.038
branching morphogenesis of an epithelial tubeGO:00487541590.038
protein maturationGO:00516041760.038
somitogenesisGO:0001756690.038
protein acylationGO:0043543640.037
positive regulation of cellular catabolic processGO:00313311480.037
protein localization to nucleusGO:00345041210.037
positive regulation of behaviorGO:0048520400.037
Fly
kidney developmentGO:00018222130.037
monosaccharide metabolic processGO:00059961060.037
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.037
Fly
cellular response to organonitrogen compoundGO:00714171450.037
Mouse Worm Fly
organelle fissionGO:00482851700.037
extracellular matrix organizationGO:00301981470.037
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.037
mapk cascadeGO:00001652810.037
regulation of mitotic cell cycle phase transitionGO:1901990730.036
Mouse
positive regulation of protein phosphorylationGO:00019342420.036
multicellular organismal signalingGO:0035637910.036
oocyte developmentGO:0048599330.036
glycosylationGO:0070085620.036
defense response to other organismGO:00985421970.036
Worm
regulation of myeloid leukocyte differentiationGO:0002761580.036
negative regulation of apoptotic signaling pathwayGO:20012341040.036
response to low density lipoprotein particleGO:005509820.036
negative regulation of phosphate metabolic processGO:00459361840.035
regulation of sequence specific dna binding transcription factor activityGO:00510901060.035
regulation of blood circulationGO:1903522930.035
intracellular steroid hormone receptor signaling pathwayGO:0030518290.034
regulation of proteolysisGO:00301621640.034
peptidyl lysine modificationGO:0018205770.034
positive regulation of reactive oxygen species metabolic processGO:2000379110.034
ribonucleotide metabolic processGO:00092592910.034
Fly
macromolecule catabolic processGO:00090572810.033
multicellular organism growthGO:00352641610.033
Worm Fly
heterocycle catabolic processGO:00467002800.033
neuron deathGO:00709971540.033
Human Zebrafish
negative regulation of cell sizeGO:004579230.033
Fly
urogenital system developmentGO:00016552610.033
regulation of purine nucleotide metabolic processGO:19005421690.033
negative regulation of cell growthGO:0030308440.033
Fly
activation of adenylate cyclase activityGO:000719040.033
positive regulation of protein catabolic processGO:0045732600.033
intracellular protein transportGO:00068862040.033
positive regulation of protein bindingGO:0032092290.032
regulation of cysteine type endopeptidase activityGO:2000116650.032
protein localization to organelleGO:00333651850.032
long term memoryGO:0007616150.032
regulation of cellular component sizeGO:00325351210.032
Fly
angiogenesisGO:00015252010.032
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.032
mitochondrion organizationGO:00070051340.032
regulation of fatty acid biosynthetic processGO:0042304120.032
pole plasm assemblyGO:000731520.032
negative regulation of hydrolase activityGO:0051346710.032
purine containing compound metabolic processGO:00725213110.032
Fly
alpha amino acid metabolic processGO:1901605590.032
positive regulation of histone methylationGO:0031062160.031
regulation of cell cycle g1 s phase transitionGO:1902806350.031
regulation of g1 s transition of mitotic cell cycleGO:2000045350.031
memoryGO:0007613580.031
regulation of transmembrane transportGO:00347621280.031
nucleoside phosphate biosynthetic processGO:1901293790.031
Fly
regulation of cell activationGO:00508652890.031
somatic stem cell maintenanceGO:0035019470.031
macromolecule glycosylationGO:0043413550.031
positive regulation of peptidase activityGO:0010952490.031
hexose metabolic processGO:0019318980.031
Mouse
muscle cell differentiationGO:00426922610.031
Fly
protein ubiquitinationGO:00165671710.030
posttranscriptional regulation of gene expressionGO:00106081550.030
Human
mitochondrion degradationGO:000042230.030
positive regulation of programmed cell deathGO:00430682180.030
Human Worm
dna integrity checkpointGO:0031570280.030
Mouse
cellular response to antibioticGO:007123640.030
regulation of dna templated transcription in response to stressGO:004362090.030
Worm
lateral inhibitionGO:004633110.030
cartilage developmentGO:00512161400.030
modification dependent macromolecule catabolic processGO:00436321330.030
sensory organ morphogenesisGO:00905962420.030
Fly
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.030
positive regulation of macroautophagyGO:001623930.029
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771240.029
multi multicellular organism processGO:00447061090.029
positive regulation of bmp signaling pathwayGO:0030513230.029
developmental maturationGO:00217001930.029
cellular response to hormone stimulusGO:00328701500.029
Mouse Worm Fly
regulation of membrane potentialGO:00423911920.029
regulation of ion transmembrane transportGO:00347651190.029
positive regulation of cellular amine metabolic processGO:003324050.029
protein kinase b signalingGO:0043491740.029
oxidation reduction processGO:00551143420.029
Fly
insulin secretionGO:0030073890.029
cellular chemical homeostasisGO:00550822150.028
segmentationGO:0035282930.028
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.028
microtubule cytoskeleton organizationGO:00002261570.028
Fly
regulation of nucleotide biosynthetic processGO:0030808340.028
regulation of protein bindingGO:0043393600.028
modification dependent protein catabolic processGO:00199411330.028
positive regulation of reactive oxygen species biosynthetic processGO:190342820.028
skeletal system morphogenesisGO:00487052030.028
single organism cell adhesionGO:00986021560.028
chromatin organizationGO:00063252060.028
regulation of sterol transportGO:0032371170.028
female gamete generationGO:0007292740.027
oocyte maturationGO:0001556180.027
regulation of chromosome organizationGO:0033044830.027
nuclear divisionGO:00002801580.027
male sex differentiationGO:00466611090.027
chondroitin sulfate proteoglycan biosynthetic processGO:005065080.027
positive regulation of mitotic sister chromatid separationGO:190197020.027
positive regulation of cell cycleGO:0045787920.027
associative learningGO:0008306610.027
regulation of mapk cascadeGO:00434082480.027
b cell differentiationGO:0030183780.027
neuron apoptotic processGO:00514021420.027
Human Zebrafish
positive regulation of epithelial cell proliferationGO:0050679680.026
protein autophosphorylationGO:0046777610.026
regulation of microtubule polymerizationGO:003111370.026
intracellular receptor signaling pathwayGO:0030522740.026
regulation of peptidase activityGO:0052547960.026
ovulationGO:0030728150.026
membrane organizationGO:00610242450.026
regulation of ion transportGO:00432692150.026
positive regulation of cysteine type endopeptidase activityGO:2001056390.026
cytokine mediated signaling pathwayGO:00192211150.026
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.026
dendrite developmentGO:00163581150.026
Fly
regulation of endopeptidase activityGO:0052548890.026
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.026
gluconeogenesisGO:0006094390.026
Mouse
lipid biosynthetic processGO:00086101790.026
Worm
cellular lipid metabolic processGO:00442553230.025
embryonic digit morphogenesisGO:0042733560.025
midbrain developmentGO:0030901350.025
germ line stem cell divisionGO:004207820.025
adult locomotory behaviorGO:0008344910.025
central nervous system neuron differentiationGO:00219531620.025
wnt signaling pathwayGO:00160551880.025
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.025
enucleate erythrocyte differentiationGO:004335380.025
negative regulation of b cell differentiationGO:004557840.025
nitrogen compound transportGO:00717052710.025
regulation of histone modificationGO:0031056560.025
regulation of transcription from rna polymerase iii promoterGO:000635920.025
exocytosisGO:00068871210.025
regulation of cellular catabolic processGO:00313292420.025
Fly
response to nitric oxideGO:007173140.024
Mouse
mesenchyme developmentGO:00604851520.024
regulation of cellular carbohydrate metabolic processGO:0010675750.024
Mouse
divalent inorganic cation transportGO:00725111780.024
myeloid cell differentiationGO:00300992330.024
Human
cell activation involved in immune responseGO:00022631260.024
meiotic cell cycleGO:00513211220.024
lipid localizationGO:00108761260.024
Fly
notch signaling pathwayGO:0007219710.024
blastocyst growthGO:0001832230.024
response to retinoic acidGO:0032526560.024
cellular response to cytokine stimulusGO:00713451890.024
transcription from rna polymerase iii promoterGO:000638330.024
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoterGO:007236470.024
Mouse
reactive nitrogen species metabolic processGO:200105700.023
regulation of lymphocyte apoptotic processGO:0070228410.023
cellular response to radiationGO:0071478280.023
regulation of insulin receptor signaling pathwayGO:0046626210.023
Fly
negative regulation of epithelial cell proliferationGO:0050680640.023
embryonic hemopoiesisGO:0035162230.023
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.023
ion transmembrane transportGO:00342203610.023
energy homeostasisGO:0097009150.023
response to ionizing radiationGO:0010212420.023
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143180.023
hormone mediated signaling pathwayGO:0009755230.023
chondroitin sulfate biosynthetic processGO:003020650.023
regulation of metal ion transportGO:00109591060.022
regulation of stem cell differentiationGO:2000736500.022
histone modificationGO:00165701590.022
positive regulation of hydrolase activityGO:00513451480.022
positive regulation of chromosome segregationGO:005198440.022
regulation of secretionGO:00510462740.022
regulation of adaptive immune responseGO:0002819900.022
Worm
purine nucleoside triphosphate metabolic processGO:00091442260.022
regulation of somitogenesisGO:001480760.022
cellular response to reactive nitrogen speciesGO:190217050.022
Mouse
sensory perception of painGO:0019233470.022
alpha beta t cell differentiationGO:0046632690.022
gland developmentGO:00487323300.022
myeloid cell homeostasisGO:00022621140.022
Human
sequestering of calcium ionGO:0051208180.022
activation of transmembrane receptor protein tyrosine kinase activityGO:000717130.022
morphogenesis of a branching epitheliumGO:00611381930.022
tissue homeostasisGO:00018941150.022
chromatin silencing at rdnaGO:000018330.021
dendritic cell cytokine productionGO:000237130.021
negative regulation of mitotic cell cycle phase transitionGO:1901991450.021
Mouse
cytokine productionGO:00018163190.021
erk1 and erk2 cascadeGO:0070371770.021
negative regulation of ossificationGO:0030279490.021
regulation of cell migrationGO:00303342190.021

Foxo3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.851
immune system diseaseDOID:291400.851
disease of cellular proliferationDOID:1456600.632
hematopoietic system diseaseDOID:7400.163
cancerDOID:16200.132
organ system cancerDOID:005068600.110
disease of metabolismDOID:001466700.094
gastrointestinal system cancerDOID:311900.060
immune system cancerDOID:006008300.052
inherited metabolic disorderDOID:65500.048
hematologic cancerDOID:253100.030
acquired metabolic diseaseDOID:006015800.029
lymphatic system diseaseDOID:7500.028
endocrine system diseaseDOID:2800.025
reproductive organ cancerDOID:19300.023