| histone methylation | GO:0016571 | 71 | 0.757 | |
| histone modification | GO:0016570 | 159 | 0.725 | |
| histone lysine methylation | GO:0034968 | 50 | 0.693 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.644 | |
| demethylation | GO:0070988 | 23 | 0.550 | |
| protein methylation | GO:0006479 | 81 | 0.374 | |
| chromatin organization | GO:0006325 | 206 | 0.346 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.262 | |
| spermatogenesis | GO:0007283 | 284 | 0.247 | |
| histone h3 k9 methylation | GO:0051567 | 17 | 0.247 | |
| histone lysine demethylation | GO:0070076 | 13 | 0.233 | |
| regulation of histone methylation | GO:0031060 | 30 | 0.230 | |
| regulation of chromatin silencing | GO:0031935 | 2 | 0.226 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.187 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.185 | |
| regulation of histone modification | GO:0031056 | 56 | 0.183 | |
| macromolecule methylation | GO:0043414 | 120 | 0.182 | |
| chromatin modification | GO:0016568 | 187 | 0.177 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.164 | |
| peptidyl lysine methylation | GO:0018022 | 29 | 0.149 | |
| regulation of histone h3 k9 methylation | GO:0051570 | 8 | 0.141 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.138 | |
| actin mediated cell contraction | GO:0070252 | 15 | 0.135 | |
| gene silencing | GO:0016458 | 38 | 0.134 | |
| protein ubiquitination | GO:0016567 | 171 | 0.130 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.129 | |
| male gamete generation | GO:0048232 | 285 | 0.129 | |
| methylation | GO:0032259 | 134 | 0.128 | |
| appendage development | GO:0048736 | 166 | 0.117 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.115 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.111 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.106 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.104 | |
| positive regulation of chromatin modification | GO:1903310 | 28 | 0.103 | |
| skeletal system development | GO:0001501 | 356 | 0.100 | |
| protein dealkylation | GO:0008214 | 13 | 0.099 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.094 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.092 | |
| ossification | GO:0001503 | 216 | 0.092 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.090 | |
| histone demethylation | GO:0016577 | 13 | 0.089 | |
| protein alkylation | GO:0008213 | 81 | 0.083 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.077 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.077 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.075 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.069 | |
| negative regulation of chromatin silencing | GO:0031936 | 1 | 0.068 | |
| positive regulation of chromosome organization | GO:2001252 | 33 | 0.066 | |
| chromatin silencing at rdna | GO:0000183 | 3 | 0.066 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.065 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.064 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.064 | |
| negative regulation of histone methylation | GO:0031061 | 10 | 0.063 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.062 | |
| amine metabolic process | GO:0009308 | 45 | 0.061 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.061 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.061 | |
| granulocyte differentiation | GO:0030851 | 17 | 0.061 | |
| epithelial cell development | GO:0002064 | 159 | 0.060 | |
| transdifferentiation | GO:0060290 | 1 | 0.059 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.058 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.057 | |
| chromatin silencing | GO:0006342 | 15 | 0.056 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.054 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.053 | |
| regulation of defense response | GO:0031347 | 233 | 0.053 | |
| protein catabolic process | GO:0030163 | 221 | 0.053 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.052 | |
| dna metabolic process | GO:0006259 | 303 | 0.050 | |
| camera type eye development | GO:0043010 | 266 | 0.050 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.048 | |
| respiratory tube development | GO:0030323 | 167 | 0.048 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.048 | |
| protein processing | GO:0016485 | 163 | 0.047 | |
| cellular response to lipid | GO:0071396 | 145 | 0.047 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.045 | |
| spermatid nucleus elongation | GO:0007290 | 4 | 0.045 | |
| hepaticobiliary system development | GO:0061008 | 67 | 0.045 | |
| embryonic skeletal system development | GO:0048706 | 120 | 0.044 | |
| cellularization | GO:0007349 | 1 | 0.043 | |
| protein demethylation | GO:0006482 | 13 | 0.043 | |
| development of primary male sexual characteristics | GO:0046546 | 88 | 0.043 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.043 | |
| respiratory system development | GO:0060541 | 190 | 0.043 | |
| negative regulation of histone modification | GO:0031057 | 18 | 0.042 | |
| protein maturation | GO:0051604 | 176 | 0.042 | |
| blood circulation | GO:0008015 | 195 | 0.042 | |
| sensory perception | GO:0007600 | 245 | 0.040 | |
| ear development | GO:0043583 | 200 | 0.039 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.038 | |
| chromatin mediated maintenance of transcription | GO:0048096 | 2 | 0.037 | |
| defecation | GO:0030421 | 1 | 0.036 | |
| bmp signaling pathway | GO:0030509 | 93 | 0.036 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.035 | |
| digestive system development | GO:0055123 | 200 | 0.035 | |
| positive regulation of histone modification | GO:0031058 | 28 | 0.035 | |
| viral transcription | GO:0019083 | 3 | 0.034 | |
| negative regulation of chromatin modification | GO:1903309 | 19 | 0.034 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.033 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.033 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.032 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.032 | |
| heart contraction | GO:0060047 | 93 | 0.031 | |
| compound eye development | GO:0048749 | 1 | 0.030 | |
| histone h3 k9 dimethylation | GO:0036123 | 4 | 0.030 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.030 | |
| histone h3 k9 trimethylation | GO:0036124 | 6 | 0.030 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.030 | |
| gland development | GO:0048732 | 330 | 0.029 | |
| positive regulation of histone h3 k9 methylation | GO:0051574 | 4 | 0.029 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.029 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.029 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.029 | |
| heart process | GO:0003015 | 94 | 0.028 | |
| positive regulation of histone methylation | GO:0031062 | 16 | 0.028 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.028 | |
| definitive hemopoiesis | GO:0060216 | 20 | 0.028 | |
| t cell activation | GO:0042110 | 289 | 0.027 | |
| placenta development | GO:0001890 | 140 | 0.027 | |
| protein deacetylation | GO:0006476 | 32 | 0.026 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.026 | |
| tube formation | GO:0035148 | 140 | 0.026 | |
| cation homeostasis | GO:0055080 | 212 | 0.026 | |
| telomere maintenance | GO:0000723 | 19 | 0.026 | |
| gonad development | GO:0008406 | 141 | 0.026 | |
| immune effector process | GO:0002252 | 321 | 0.025 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.025 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.025 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.025 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.025 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.025 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.025 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.025 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.025 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.025 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.024 | |
| lung development | GO:0030324 | 164 | 0.024 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.024 | |
| regulation of transcription by chromatin organization | GO:0034401 | 0 | 0.024 | |
| epithelial tube formation | GO:0072175 | 130 | 0.023 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.023 | |
| male gonad development | GO:0008584 | 88 | 0.023 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.022 | |
| blastocyst development | GO:0001824 | 80 | 0.022 | |
| histone h3 k36 demethylation | GO:0070544 | 2 | 0.022 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.022 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.022 | |
| microtubule anchoring at microtubule organizing center | GO:0072393 | 5 | 0.021 | |
| hair cycle | GO:0042633 | 90 | 0.021 | |
| regulation of viral transcription | GO:0046782 | 3 | 0.021 | |
| male sex differentiation | GO:0046661 | 109 | 0.021 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.021 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.021 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.021 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.021 | |
| multicellular organism growth | GO:0035264 | 161 | 0.021 | |
| histone h3 k4 trimethylation | GO:0080182 | 5 | 0.020 | |
| embryonic placenta development | GO:0001892 | 98 | 0.020 | |
| forebrain development | GO:0030900 | 302 | 0.020 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.020 | |
| mapk cascade | GO:0000165 | 281 | 0.019 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.019 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 75 | 0.019 | |
| regulation of system process | GO:0044057 | 200 | 0.019 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.019 | |
| cellular magnesium ion homeostasis | GO:0010961 | 3 | 0.019 | |
| chemotaxis | GO:0006935 | 247 | 0.018 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.018 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.018 | |
| embryonic process involved in female pregnancy | GO:0060136 | 7 | 0.018 | |
| limb morphogenesis | GO:0035108 | 149 | 0.018 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.018 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.017 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.017 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.017 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.016 | |
| t cell differentiation | GO:0030217 | 174 | 0.016 | |
| neural tube development | GO:0021915 | 160 | 0.016 | |
| protein acylation | GO:0043543 | 64 | 0.016 | |
| phenol containing compound metabolic process | GO:0018958 | 60 | 0.016 | |
| protein deacylation | GO:0035601 | 36 | 0.016 | |
| organelle fission | GO:0048285 | 170 | 0.015 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.015 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.015 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.015 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.015 | |
| response to acid chemical | GO:0001101 | 111 | 0.015 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.015 | |
| natural killer cell activation | GO:0030101 | 44 | 0.015 | |
| negative regulation of leukocyte proliferation | GO:0070664 | 46 | 0.015 | |
| histone deacetylation | GO:0016575 | 26 | 0.015 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.015 | |
| maintenance of location | GO:0051235 | 89 | 0.014 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.014 | |
| cellular homeostasis | GO:0019725 | 240 | 0.014 | |
| fibroblast proliferation | GO:0048144 | 35 | 0.014 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.014 | |
| regulation of gene silencing | GO:0060968 | 7 | 0.014 | |
| ear morphogenesis | GO:0042471 | 118 | 0.014 | |
| regulation of secretion | GO:0051046 | 274 | 0.014 | |
| actin filament based movement | GO:0030048 | 23 | 0.014 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.014 | |
| regulation of protein stability | GO:0031647 | 52 | 0.014 | |
| natural killer cell differentiation | GO:0001779 | 21 | 0.014 | |
| learning or memory | GO:0007611 | 148 | 0.014 | |
| rna processing | GO:0006396 | 105 | 0.014 | |
| stem cell differentiation | GO:0048863 | 268 | 0.014 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.014 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.014 | |
| bone mineralization | GO:0030282 | 54 | 0.014 | |
| histone h3 k4 methylation | GO:0051568 | 23 | 0.014 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.013 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.013 | |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.013 | |
| negative regulation of lymphocyte proliferation | GO:0050672 | 45 | 0.013 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 15 | 0.013 | |
| regulation of histone deacetylation | GO:0031063 | 12 | 0.013 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.013 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.013 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.013 | |
| regulation of protein transport | GO:0051223 | 163 | 0.013 | |
| response to inorganic substance | GO:0010035 | 96 | 0.013 | |
| stem cell development | GO:0048864 | 219 | 0.013 | |
| germ cell development | GO:0007281 | 185 | 0.013 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.013 | |
| digestive tract development | GO:0048565 | 190 | 0.013 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.012 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.012 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.012 | |
| inner ear morphogenesis | GO:0042472 | 101 | 0.012 | |
| protein homotrimerization | GO:0070207 | 4 | 0.012 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.012 | |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.012 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.012 | |
| primary neural tube formation | GO:0014020 | 95 | 0.012 | |
| mitotic sister chromatid cohesion | GO:0007064 | 1 | 0.012 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.012 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.012 | |
| regulation of embryonic development | GO:0045995 | 71 | 0.012 | |
| inflammatory response | GO:0006954 | 244 | 0.012 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.012 | |
| bone development | GO:0060348 | 120 | 0.012 | |
| limb development | GO:0060173 | 166 | 0.011 | |
| bone morphogenesis | GO:0060349 | 78 | 0.011 | |
| pharynx development | GO:0060465 | 1 | 0.011 | |
| negative regulation of b cell proliferation | GO:0030889 | 13 | 0.011 | |
| cd4 positive alpha beta t cell activation | GO:0035710 | 45 | 0.011 | |
| female gamete generation | GO:0007292 | 74 | 0.011 | |
| defense response to other organism | GO:0098542 | 197 | 0.011 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.011 | |
| rna splicing | GO:0008380 | 54 | 0.011 | |
| pigment metabolic process | GO:0042440 | 32 | 0.011 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.011 | |
| embryonic appendage morphogenesis | GO:0035113 | 126 | 0.011 | |
| axon guidance | GO:0007411 | 141 | 0.011 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.011 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.011 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.011 | |
| b cell activation | GO:0042113 | 161 | 0.011 | |
| cellular response to steroid hormone stimulus | GO:0071383 | 33 | 0.011 | |
| negative regulation of binding | GO:0051100 | 39 | 0.011 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.011 | |
| signal transduction involved in cell cycle checkpoint | GO:0072395 | 3 | 0.011 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.011 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.011 | |
| trophectodermal cell differentiation | GO:0001829 | 21 | 0.010 | |
| regulation of protein processing | GO:0070613 | 96 | 0.010 | |
| tube closure | GO:0060606 | 91 | 0.010 | |
| negative regulation of gene silencing | GO:0060969 | 2 | 0.010 | |
| regulation of b cell proliferation | GO:0030888 | 39 | 0.010 | |
