IMP: Integrative Multi-species Prediction

Mus musculus

32 known processes

Gbp7

guanylate binding protein 7

(Aliases: 9830147J24Rik)

Ensembl: ENSMUSG00000040253
Entrez: 229900
UniProtKB: Q78UK8
UniProtKB: Q91Z40

Process Predictions
Disease Predictions

Gbp7 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular response to interferon beta	GO:0035458	21	0.998	Mouse
defense response to protozoan	GO:0042832	25	0.995
defense response to virus	GO:0051607	68	0.995	Mouse
defense response to other organism	GO:0098542	197	0.994
regulation of defense response to virus by host	GO:0050691	8	0.986
regulation of defense response	GO:0031347	233	0.982	Mouse
regulation of interferon alpha production	GO:0032647	5	0.972	Mouse
response to interferon gamma	GO:0034341	34	0.964
activation of innate immune response	GO:0002218	56	0.956
cellular response to cytokine stimulus	GO:0071345	189	0.953
innate immune response	GO:0045087	157	0.952
type i interferon production	GO:0032606	29	0.950	Mouse
interspecies interaction between organisms	GO:0044419	83	0.943
immune effector process	GO:0002252	321	0.942	Mouse
negative regulation of interferon alpha production	GO:0032687	1	0.942	Mouse
regulation of cytokine production	GO:0001817	266	0.941	Mouse
regulation of defense response to virus	GO:0050688	18	0.940	Mouse
defense response to bacterium	GO:0042742	119	0.940
response to protozoan	GO:0001562	28	0.930
response to interferon beta	GO:0035456	22	0.913	Mouse
positive regulation of rig i signaling pathway	GO:1900246	1	0.902
cellular response to interferon gamma	GO:0071346	25	0.891
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.889
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.871
regulation of response to biotic stimulus	GO:0002831	38	0.859	Mouse
rig i signaling pathway	GO:0039529	4	0.858
cytokine production	GO:0001816	319	0.832	Mouse
positive regulation of interferon alpha production	GO:0032727	4	0.827
negative regulation of nlrp3 inflammasome complex assembly	GO:1900226	2	0.819
negative regulation of viral process	GO:0048525	23	0.788
regulation of nlrp3 inflammasome complex assembly	GO:1900225	4	0.784
negative regulation of cytokine production	GO:0001818	84	0.778	Mouse
positive regulation of viral genome replication	GO:0045070	2	0.750
negative regulation of cell proliferation	GO:0008285	296	0.740
regulation of innate immune response	GO:0045088	91	0.737
pattern recognition receptor signaling pathway	GO:0002221	47	0.732
protein modification by small protein conjugation	GO:0032446	187	0.709	Mouse
viral genome replication	GO:0019079	17	0.682
positive regulation of innate immune response	GO:0045089	80	0.677
response to lipopolysaccharide	GO:0032496	128	0.666	Mouse
positive regulation of viral entry into host cell	GO:0046598	3	0.665
regulation of multi organism process	GO:0043900	111	0.659	Mouse
viral life cycle	GO:0019058	36	0.631
innate immune response activating signal transduction	GO:0002758	50	0.614
defense response to gram negative bacterium	GO:0050829	28	0.597
positive regulation of defense response	GO:0031349	124	0.591
autophagy	GO:0006914	45	0.572
cellular response to lipid	GO:0071396	145	0.552	Mouse
protein modification by small protein conjugation or removal	GO:0070647	207	0.535	Mouse
regulation of defense response to bacterium	GO:1900424	3	0.522
negative regulation of multi organism process	GO:0043901	68	0.506
cellular response to interferon alpha	GO:0035457	4	0.500
regulation of toll like receptor signaling pathway	GO:0034121	20	0.477
regulation of rig i signaling pathway	GO:0039535	2	0.477
adhesion of symbiont to host	GO:0044406	8	0.474
positive regulation of t cell mediated cytotoxicity	GO:0001916	15	0.463
regulation of type i interferon production	GO:0032479	22	0.441	Mouse
interferon beta production	GO:0032608	16	0.419
protein ubiquitination	GO:0016567	171	0.417	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	247	0.413	Mouse
viral process	GO:0016032	41	0.407
production of small rna involved in gene silencing by rna	GO:0070918	6	0.405
regulation of viral genome replication	GO:0045069	13	0.401
viral transcription	GO:0019083	3	0.389
cd8 positive alpha beta t cell proliferation	GO:0035740	1	0.388
negative regulation of defense response	GO:0031348	77	0.382
organic cyclic compound catabolic process	GO:1901361	295	0.378
positive regulation of cytokine production	GO:0001819	174	0.373
negative regulation of immune system process	GO:0002683	209	0.370
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.359
immune response regulating signaling pathway	GO:0002764	125	0.349
cellular nitrogen compound catabolic process	GO:0044270	280	0.347
nucleocytoplasmic transport	GO:0006913	139	0.343	Mouse
movement in host environment	GO:0052126	15	0.342
viral gene expression	GO:0019080	3	0.331
positive regulation of immune effector process	GO:0002699	107	0.329
regulation of t cell activation	GO:0050863	170	0.329
negative regulation of protein metabolic process	GO:0051248	282	0.326	Mouse
cellular response to lipopolysaccharide	GO:0071222	77	0.319	Mouse
pyroptosis	GO:0070269	8	0.316
positive regulation of type i interferon mediated signaling pathway	GO:0060340	4	0.307
negative regulation of viral entry into host cell	GO:0046597	10	0.304
negative regulation of defense response to virus by host	GO:0050689	1	0.295
nucleoside triphosphate metabolic process	GO:0009141	230	0.284
aromatic compound catabolic process	GO:0019439	286	0.281
regulation of myd88 independent toll like receptor signaling pathway	GO:0034127	1	0.281
purine nucleotide catabolic process	GO:0006195	211	0.278
regulation of protein transport	GO:0051223	163	0.277	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.275
negative regulation of viral release from host cell	GO:1902187	6	0.274
defense response to gram positive bacterium	GO:0050830	50	0.270
guanosine containing compound metabolic process	GO:1901068	144	0.269
myeloid leukocyte differentiation	GO:0002573	119	0.268
response to molecule of bacterial origin	GO:0002237	143	0.268	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.266	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.253
cytoplasmic pattern recognition receptor signaling pathway in response to virus	GO:0039528	4	0.250
immune response activating signal transduction	GO:0002757	116	0.246
mda 5 signaling pathway	GO:0039530	1	0.227
activation of immune response	GO:0002253	138	0.226
regulation of protein localization	GO:0032880	231	0.226	Mouse
regulation of viral release from host cell	GO:1902186	6	0.226
negative regulation of toll like receptor signaling pathway	GO:0034122	14	0.224
purine ribonucleoside metabolic process	GO:0046128	241	0.223
nlrp3 inflammasome complex assembly	GO:0044546	5	0.223
nucleoside phosphate metabolic process	GO:0006753	338	0.222
organophosphate catabolic process	GO:0046434	232	0.218
entry into cell of other organism involved in symbiotic interaction	GO:0051806	15	0.215
negative regulation of defense response to virus	GO:0050687	6	0.213
protein import into nucleus	GO:0006606	95	0.208	Mouse
regulation of cellular catabolic process	GO:0031329	242	0.205
gtp catabolic process	GO:0006184	143	0.204
negative regulation of phosphate metabolic process	GO:0045936	184	0.204	Mouse
purine ribonucleoside catabolic process	GO:0046130	205	0.200
heterocycle catabolic process	GO:0046700	280	0.200
cellular response to type i interferon	GO:0071357	10	0.197
macromolecule catabolic process	GO:0009057	281	0.197
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.194
purine ribonucleotide catabolic process	GO:0009154	208	0.192
myeloid cell differentiation	GO:0030099	233	0.191
negative regulation of necroptotic process	GO:0060546	9	0.188
purine containing compound metabolic process	GO:0072521	311	0.187
negative regulation of intracellular protein transport	GO:0090317	27	0.187	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.180
gtp metabolic process	GO:0046039	144	0.179
negative regulation of cytoplasmic transport	GO:1903650	29	0.179	Mouse
interaction with host	GO:0051701	22	0.178
ribonucleotide catabolic process	GO:0009261	208	0.176
ribonucleoside metabolic process	GO:0009119	245	0.174
response to interferon alpha	GO:0035455	7	0.170
nucleobase containing small molecule metabolic process	GO:0055086	352	0.168
purine containing compound catabolic process	GO:0072523	213	0.167
negative regulation of nucleocytoplasmic transport	GO:0046823	23	0.166	Mouse
t cell mediated cytotoxicity	GO:0001913	26	0.165
purine nucleoside metabolic process	GO:0042278	241	0.164
nucleotide catabolic process	GO:0009166	217	0.162
ribonucleotide metabolic process	GO:0009259	291	0.160
negative regulation of protein modification process	GO:0031400	163	0.159	Mouse
cellular macromolecule catabolic process	GO:0044265	206	0.157
regulation of natural killer cell mediated cytotoxicity	GO:0042269	19	0.156
negative regulation of cell activation	GO:0050866	111	0.151
regulation of autophagy	GO:0010506	30	0.149
negative regulation of interferon beta production	GO:0032688	3	0.149
positive regulation of viral process	GO:0048524	5	0.145
toll like receptor signaling pathway	GO:0002224	38	0.144
regulation of type i interferon mediated signaling pathway	GO:0060338	7	0.140
nucleoside triphosphate catabolic process	GO:0009143	205	0.138
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.137
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.136
negative regulation of immune effector process	GO:0002698	55	0.135
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.134	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.134
nucleoside metabolic process	GO:0009116	246	0.133
regulation of necroptotic process	GO:0060544	10	0.133
positive regulation of actin nucleation	GO:0051127	3	0.131
negative regulation of phosphorylation	GO:0042326	166	0.131	Mouse
angiogenesis	GO:0001525	201	0.131
negative regulation of phosphorus metabolic process	GO:0010563	184	0.129	Mouse
regulation of actin nucleation	GO:0051125	4	0.127
nucleotide metabolic process	GO:0009117	332	0.127
glycosyl compound catabolic process	GO:1901658	206	0.126
protein catabolic process	GO:0030163	221	0.123
cytokine mediated signaling pathway	GO:0019221	115	0.122
cellular response to molecule of bacterial origin	GO:0071219	83	0.120	Mouse
negative regulation of intracellular transport	GO:0032387	38	0.116	Mouse
negative regulation of viral genome replication	GO:0045071	10	0.115
cell fate commitment	GO:0045165	210	0.115
nucleoside catabolic process	GO:0009164	206	0.114
guanosine containing compound catabolic process	GO:1901069	144	0.114
positive regulation of peptidase activity	GO:0010952	49	0.114
extrinsic apoptotic signaling pathway	GO:0097191	126	0.113
leukocyte mediated cytotoxicity	GO:0001909	62	0.113
positive regulation of interleukin 1 alpha secretion	GO:0050717	3	0.112
regulation of intracellular transport	GO:0032386	159	0.112	Mouse
regulation of cell activation	GO:0050865	289	0.111
cell killing	GO:0001906	67	0.110
purine nucleotide metabolic process	GO:0006163	302	0.109
regulation of adaptive immune response	GO:0002819	90	0.109
leukocyte mediated immunity	GO:0002443	174	0.108
nucleoside phosphate catabolic process	GO:1901292	222	0.108
i kappab kinase nf kappab signaling	GO:0007249	85	0.106
protein localization to nucleus	GO:0034504	121	0.103	Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.103
regulation of myd88 dependent toll like receptor signaling pathway	GO:0034124	2	0.102
negative regulation of innate immune response	GO:0045824	17	0.101
lymphocyte homeostasis	GO:0002260	64	0.099
nuclear transport	GO:0051169	139	0.099	Mouse
regulation of cell killing	GO:0031341	40	0.099
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway	GO:0039531	2	0.097
epithelial tube morphogenesis	GO:0060562	303	0.096
negative regulation of nervous system development	GO:0051961	156	0.094
lymphocyte mediated immunity	GO:0002449	139	0.093
purine nucleoside catabolic process	GO:0006152	205	0.093
organonitrogen compound catabolic process	GO:1901565	264	0.092
myeloid cell homeostasis	GO:0002262	114	0.092
interferon alpha production	GO:0032607	7	0.091	Mouse
regulation of protein targeting	GO:1903533	61	0.090	Mouse
regulation of viral entry into host cell	GO:0046596	12	0.089
regulation of nucleocytoplasmic transport	GO:0046822	73	0.087	Mouse
cytoplasmic transport	GO:0016482	234	0.086	Mouse
regulation of lymphocyte activation	GO:0051249	240	0.086
skin development	GO:0043588	220	0.084
organism emergence from protective structure	GO:0071684	4	0.083
homeostasis of number of cells	GO:0048872	210	0.082
regulation of interleukin 1 alpha production	GO:0032650	4	0.082
positive regulation of type i interferon production	GO:0032481	14	0.082
t cell activation	GO:0042110	289	0.082
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.081
ribonucleoside catabolic process	GO:0042454	206	0.080
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.079
regulation of membrane potential	GO:0042391	192	0.079
negative regulation of protein phosphorylation	GO:0001933	126	0.079	Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.078
negative regulation of binding	GO:0051100	39	0.078
regulation of intracellular protein transport	GO:0033157	82	0.078	Mouse
adaptive immune response	GO:0002250	155	0.077
negative regulation of protein transport	GO:0051224	46	0.077	Mouse
schwann cell proliferation	GO:0014010	2	0.076
movement in environment of other organism involved in symbiotic interaction	GO:0052192	15	0.076
regulation of cell cycle	GO:0051726	281	0.074
negative regulation of protein modification by small protein conjugation or removal	GO:1903321	20	0.074	Mouse
negative regulation of t cell activation	GO:0050868	65	0.074
positive regulation of proteolysis	GO:0045862	85	0.073
regulation of protein ubiquitination	GO:0031396	52	0.073	Mouse
signal transduction in absence of ligand	GO:0038034	55	0.073
regulation of leukocyte differentiation	GO:1902105	159	0.069
erythrocyte differentiation	GO:0030218	88	0.069
regulation of leukocyte apoptotic process	GO:2000106	56	0.068
negative regulation of molecular function	GO:0044092	258	0.066
entry into host cell	GO:0030260	15	0.066
regulation of protein import into nucleus	GO:0042306	52	0.065	Mouse
regulation of interferon gamma production	GO:0032649	57	0.064
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.064
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.062
viral release from host cell	GO:0019076	6	0.062
response to type i interferon	GO:0034340	12	0.062
response to organic cyclic compound	GO:0014070	198	0.060
negative regulation of viral transcription	GO:0032897	3	0.058
entry into host	GO:0044409	15	0.058
apoptotic signaling pathway	GO:0097190	306	0.058
viral entry into host cell	GO:0046718	15	0.058
leukocyte activation involved in immune response	GO:0002366	126	0.058
protein import	GO:0017038	101	0.058	Mouse
negative regulation of rig i signaling pathway	GO:0039536	2	0.057
lipopolysaccharide mediated signaling pathway	GO:0031663	25	0.055
reactive oxygen species metabolic process	GO:0072593	84	0.054
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.054
t cell proliferation	GO:0042098	120	0.054
protein targeting	GO:0006605	143	0.054	Mouse
nuclear import	GO:0051170	95	0.052	Mouse
keratinocyte differentiation	GO:0030216	48	0.052
positive regulation of mapk cascade	GO:0043410	170	0.052
inflammatory response	GO:0006954	244	0.052
positive regulation of interleukin 1 secretion	GO:0050716	14	0.051
syncytium formation by plasma membrane fusion	GO:0000768	42	0.051
positive regulation of programmed cell death	GO:0043068	218	0.051
regulation of leukocyte mediated cytotoxicity	GO:0001910	38	0.051
intracellular protein transport	GO:0006886	204	0.051	Mouse
cellular response to biotic stimulus	GO:0071216	92	0.050	Mouse
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.050
t cell lineage commitment	GO:0002360	13	0.050
positive regulation of cell killing	GO:0031343	33	0.049
positive regulation of cysteine type endopeptidase activity	GO:2001056	39	0.049
apoptotic nuclear changes	GO:0030262	9	0.049
protein localization to organelle	GO:0033365	185	0.049	Mouse
regulation of apoptotic signaling pathway	GO:2001233	197	0.048
regulation of lymphocyte apoptotic process	GO:0070228	41	0.047
regulation of endopeptidase activity	GO:0052548	89	0.046
multi organism metabolic process	GO:0044033	7	0.046
regulation of t cell proliferation	GO:0042129	92	0.046
antimicrobial peptide biosynthetic process	GO:0002777	2	0.045
t cell differentiation	GO:0030217	174	0.045
dna metabolic process	GO:0006259	303	0.045
positive regulation of extrinsic apoptotic signaling pathway	GO:2001238	34	0.045
epithelial cell proliferation	GO:0050673	174	0.045
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO:2001267	4	0.044
negative regulation of necrotic cell death	GO:0060547	11	0.044
positive regulation of myelination	GO:0031643	5	0.044
hair follicle cell proliferation	GO:0071335	3	0.044
activation of cysteine type endopeptidase activity	GO:0097202	27	0.043
oligodendrocyte differentiation	GO:0048709	53	0.043
regulation of cellular amino acid metabolic process	GO:0006521	5	0.042
regulation of peptidase activity	GO:0052547	96	0.042
regulation of lymphocyte mediated immunity	GO:0002706	84	0.042
regulation of protein localization to nucleus	GO:1900180	60	0.042	Mouse
entry into other organism involved in symbiotic interaction	GO:0051828	15	0.042
engulfment of apoptotic cell	GO:0043652	3	0.042
stem cell development	GO:0048864	219	0.042
epithelial cell development	GO:0002064	159	0.041
protein oligomerization	GO:0051259	67	0.041
regulation of t cell mediated cytotoxicity	GO:0001914	18	0.040
regulation of viral transcription	GO:0046782	3	0.040
stem cell differentiation	GO:0048863	268	0.039
embryonic epithelial tube formation	GO:0001838	130	0.039
regulation of interleukin 4 biosynthetic process	GO:0045402	3	0.039
dendrite development	GO:0016358	115	0.039
response to endoplasmic reticulum stress	GO:0034976	53	0.039
blood vessel morphogenesis	GO:0048514	285	0.039
alpha beta t cell activation involved in immune response	GO:0002287	31	0.039
positive regulation of natural killer cell mediated immunity	GO:0002717	16	0.038
compound eye development	GO:0048749	1	0.038
toll like receptor 7 signaling pathway	GO:0034154	4	0.038
t cell apoptotic process	GO:0070231	39	0.038
neuronal action potential	GO:0019228	54	0.038
intrinsic apoptotic signaling pathway in response to oxidative stress	GO:0008631	19	0.038
leukocyte proliferation	GO:0070661	172	0.037
modification dependent macromolecule catabolic process	GO:0043632	133	0.037
ossification	GO:0001503	216	0.037
antibacterial peptide production	GO:0002778	2	0.037
regulation of secretion by cell	GO:1903530	249	0.037
branching morphogenesis of an epithelial tube	GO:0048754	159	0.036
protein maturation	GO:0051604	176	0.036
regulation of cytokine biosynthetic process	GO:0042035	59	0.036
positive regulation of gliogenesis	GO:0014015	27	0.036
regulation of antimicrobial humoral response	GO:0002759	3	0.036
positive regulation of antimicrobial humoral response	GO:0002760	2	0.036
gland development	GO:0048732	330	0.035
cellular amino acid metabolic process	GO:0006520	103	0.035
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.035
response to unfolded protein	GO:0006986	21	0.035
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway	GO:0039532	2	0.034
positive regulation of interleukin 1 alpha production	GO:0032730	4	0.034
natural killer cell mediated cytotoxicity	GO:0042267	29	0.033
positive regulation of leukocyte mediated cytotoxicity	GO:0001912	31	0.033
positive regulation of natural killer cell mediated cytotoxicity	GO:0045954	16	0.033
covalent chromatin modification	GO:0016569	163	0.033
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.033
allantoin metabolic process	GO:0000255	3	0.033
lymphocyte differentiation	GO:0030098	242	0.032
cellular amine metabolic process	GO:0044106	44	0.032
protein secretion	GO:0009306	111	0.032
response to dsrna	GO:0043331	30	0.032
t helper 17 cell lineage commitment	GO:0072540	4	0.032
regulation of interferon beta production	GO:0032648	13	0.032
hatching	GO:0035188	4	0.031
epidermis development	GO:0008544	187	0.031
t cell mediated immunity	GO:0002456	50	0.031
regulation of protein complex assembly	GO:0043254	83	0.031
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.031
posttranscriptional regulation of gene expression	GO:0010608	155	0.031
cellular response to dna damage stimulus	GO:0006974	207	0.030
hematopoietic progenitor cell differentiation	GO:0002244	143	0.030
regulation of response to wounding	GO:1903034	189	0.030
positive regulation of interferon gamma production	GO:0032729	39	0.030
protein processing	GO:0016485	163	0.030
multicellular organismal signaling	GO:0035637	91	0.029
syncytium formation	GO:0006949	43	0.029
regulation of syncytium formation by plasma membrane fusion	GO:0060142	23	0.029
programmed necrotic cell death	GO:0097300	28	0.029
cd4 positive alpha beta t cell lineage commitment	GO:0043373	6	0.029
response to topologically incorrect protein	GO:0035966	25	0.029
mitochondrion organization	GO:0007005	134	0.029
morphogenesis of embryonic epithelium	GO:0016331	159	0.029
leukocyte differentiation	GO:0002521	342	0.028
positive regulation of protein complex assembly	GO:0031334	45	0.028
muscle tissue development	GO:0060537	308	0.028
membrane depolarization	GO:0051899	64	0.028
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	55	0.028
regulation of cytoplasmic transport	GO:1903649	112	0.028	Mouse
spleen development	GO:0048536	39	0.027
cytokine secretion	GO:0050663	72	0.027
isg15 protein conjugation	GO:0032020	4	0.027
positive regulation of secretion by cell	GO:1903532	114	0.027
regulation of cellular component biogenesis	GO:0044087	181	0.027
tumor necrosis factor production	GO:0032640	50	0.027
cerebral cortex development	GO:0021987	86	0.027
regulation of hydrolase activity	GO:0051336	246	0.027
tumor necrosis factor superfamily cytokine production	GO:0071706	51	0.027
er nucleus signaling pathway	GO:0006984	27	0.027
cellularization	GO:0007349	1	0.027
natural killer cell proliferation	GO:0001787	3	0.027
ear development	GO:0043583	200	0.027
interferon gamma production	GO:0032609	67	0.027
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	16	0.026
cell type specific apoptotic process	GO:0097285	268	0.026
sperm individualization	GO:0007291	1	0.026
germ cell development	GO:0007281	185	0.026
regulation of lymphocyte proliferation	GO:0050670	117	0.026
regulation of secretion	GO:0051046	274	0.026
positive regulation of protein catabolic process	GO:0045732	60	0.026
isotype switching	GO:0045190	36	0.026
developmental maturation	GO:0021700	193	0.026
epidermis morphogenesis	GO:0048730	33	0.026
tube formation	GO:0035148	140	0.026
positive regulation of endopeptidase activity	GO:0010950	43	0.026
positive regulation of cell death	GO:0010942	224	0.026
production of molecular mediator of immune response	GO:0002440	103	0.025
iron ion import into cell	GO:0097459	4	0.025
extrinsic apoptotic signaling pathway via death domain receptors	GO:0008625	34	0.025
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.025
positive regulation of cellular component biogenesis	GO:0044089	94	0.025
lymphocyte proliferation	GO:0046651	164	0.025
telencephalon development	GO:0021537	186	0.025
macrophage migration inhibitory factor signaling pathway	GO:0035691	2	0.025
cellular protein catabolic process	GO:0044257	155	0.025
positive regulation of multi organism process	GO:0043902	26	0.024
type i interferon signaling pathway	GO:0060337	10	0.024
epithelial tube formation	GO:0072175	130	0.024
regulation of neuron death	GO:1901214	134	0.024
negative regulation of cellular component organization	GO:0051129	194	0.024
cellular response to organic cyclic compound	GO:0071407	87	0.024
regulation of proteolysis	GO:0030162	164	0.024
modification dependent protein catabolic process	GO:0019941	133	0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.024
regulation of regulatory t cell differentiation	GO:0045589	7	0.024
hair follicle morphogenesis	GO:0031069	29	0.023
negative regulation of protein binding	GO:0032091	17	0.023
positive regulation of organelle organization	GO:0010638	128	0.023
regulation of production of molecular mediator of immune response	GO:0002700	65	0.023
cartilage development	GO:0051216	140	0.023
neural tube formation	GO:0001841	108	0.023
positive regulation of adaptive immune response	GO:0002821	61	0.023
regulation of gliogenesis	GO:0014013	50	0.023
regulation of organ morphogenesis	GO:2000027	144	0.023
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.023
glial cell apoptotic process	GO:0034349	3	0.023
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	36	0.023
negative regulation of natural killer cell mediated immunity	GO:0002716	5	0.023
lymphocyte apoptotic process	GO:0070227	54	0.022
cell activation involved in immune response	GO:0002263	126	0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO:2001269	3	0.022
negative regulation of protein import into nucleus	GO:0042308	21	0.022	Mouse
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	1	0.022
lung development	GO:0030324	164	0.022
single organism nuclear import	GO:1902593	95	0.022	Mouse
negative regulation of cyclin dependent protein serine threonine kinase activity	GO:0045736	9	0.022
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.022
negative regulation of cell development	GO:0010721	169	0.021
regulation of cd8 positive alpha beta t cell proliferation	GO:2000564	1	0.021
positive regulation of interleukin 1 beta production	GO:0032731	16	0.021
protein polyubiquitination	GO:0000209	33	0.021
response to organonitrogen compound	GO:0010243	246	0.021
glial cell development	GO:0021782	54	0.021
regulation of mirna metabolic process	GO:2000628	4	0.021
positive regulation of defense response to bacterium	GO:1900426	1	0.021
regulation of neuron apoptotic process	GO:0043523	122	0.020
gliogenesis	GO:0042063	141	0.020
cellular response to topologically incorrect protein	GO:0035967	25	0.020
regulation of activated t cell proliferation	GO:0046006	16	0.020
interleukin 1 beta secretion	GO:0050702	16	0.020
necroptotic process	GO:0070266	21	0.020
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.020
necrotic cell death	GO:0070265	30	0.020
limb development	GO:0060173	166	0.020
regulation of actin filament polymerization	GO:0030833	38	0.020
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.020
regulation of hormone levels	GO:0010817	211	0.020
positive regulation of hematopoietic stem cell migration	GO:2000473	1	0.020
regulation of homeostatic process	GO:0032844	182	0.019
rna interference	GO:0016246	2	0.019
muscle cell development	GO:0055001	133	0.019
respiratory tube development	GO:0030323	167	0.019
spermatid differentiation	GO:0048515	115	0.019
regulation of protein secretion	GO:0050708	82	0.019
negative regulation of t cell proliferation	GO:0042130	38	0.019
positive regulation of myeloid cell differentiation	GO:0045639	43	0.019
regulation of interleukin 1 alpha secretion	GO:0050705	3	0.019
multicellular organism growth	GO:0035264	161	0.019
negative regulation of intracellular signal transduction	GO:1902532	167	0.019
organophosphate biosynthetic process	GO:0090407	122	0.019
b cell activation	GO:0042113	161	0.019
leukocyte homeostasis	GO:0001776	79	0.019
spermatogenesis	GO:0007283	284	0.019
stem cell proliferation	GO:0072089	117	0.018
regulation of muscle cell apoptotic process	GO:0010660	17	0.018
pre mirna processing	GO:0031054	3	0.018
regulation of protein processing	GO:0070613	96	0.018
positive regulation of mirna metabolic process	GO:2000630	1	0.018
antimicrobial peptide production	GO:0002775	2	0.018
regulation of t cell mediated immunity	GO:0002709	34	0.018
ubiquitin dependent protein catabolic process	GO:0006511	129	0.018
citrate metabolic process	GO:0006101	3	0.018
regulation of neutrophil mediated killing of gram negative bacterium	GO:0070951	1	0.018
regulation of tumor necrosis factor production	GO:0032680	49	0.018
regulation of leukocyte mediated immunity	GO:0002703	104	0.018
cellular component disassembly involved in execution phase of apoptosis	GO:0006921	9	0.018
regulation of inflammatory response	GO:0050727	147	0.018
interferon gamma mediated signaling pathway	GO:0060333	5	0.018
negative regulation of cell cycle	GO:0045786	123	0.018
positive regulation of lymphocyte mediated immunity	GO:0002708	62	0.018
chromatin organization	GO:0006325	206	0.018
protein acylation	GO:0043543	64	0.018
negative regulation of lymphocyte activation	GO:0051250	91	0.017
regulation of interleukin 12 production	GO:0032655	30	0.017
positive regulation of t cell activation	GO:0050870	101	0.017
regulation of epithelial cell proliferation	GO:0050678	141	0.017
histone acetylation	GO:0016573	41	0.017
regulation of b cell activation	GO:0050864	81	0.017
somatic cell dna recombination	GO:0016444	51	0.017
regulation of interleukin 6 production	GO:0032675	55	0.017
myeloid leukocyte activation	GO:0002274	83	0.017
positive regulation of leukocyte differentiation	GO:1902107	86	0.017
male gamete generation	GO:0048232	285	0.017
macromolecule methylation	GO:0043414	120	0.017

Gbp7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of cellular proliferation	DOID:14566	0	0.021

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