Mus musculus

43 known processes

Gbp6

guanylate binding protein 6

(Aliases: Mpa2l,AI595338)

Gbp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to interferon betaGO:0035458210.909
defense response to protozoanGO:0042832250.731
defense response to virusGO:0051607680.675
Mouse
response to protozoanGO:0001562280.612
innate immune responseGO:00450871570.531
regulation of defense responseGO:00313472330.527
Mouse
symbiosis encompassing mutualism through parasitismGO:0044403830.513
cytokine productionGO:00018163190.480
Mouse
regulation of cytokine productionGO:00018172660.460
Mouse
response to interferon gammaGO:0034341340.441
defense response to other organismGO:00985421970.413
immune effector processGO:00022523210.395
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.374
Mouse
response to interferon betaGO:0035456220.308
defense response to bacteriumGO:00427421190.305
cellular response to lipopolysaccharideGO:0071222770.303
response to molecule of bacterial originGO:00022371430.284
defense response to gram positive bacteriumGO:0050830500.247
protein modification by small protein conjugation or removalGO:00706472070.247
Mouse
negative regulation of phosphate metabolic processGO:00459361840.246
Mouse
regulation of protein transportGO:00512231630.239
Mouse
regulation of type i interferon productionGO:0032479220.232
Mouse
protein ubiquitinationGO:00165671710.232
Mouse
cellular response to biotic stimulusGO:0071216920.223
cellular response to interferon gammaGO:0071346250.207
regulation of intracellular transportGO:00323861590.206
Mouse
regulation of response to biotic stimulusGO:0002831380.200
Mouse
negative regulation of protein phosphorylationGO:00019331260.192
Mouse
negative regulation of interferon alpha productionGO:003268710.190
Mouse
negative regulation of cytokine productionGO:0001818840.187
Mouse
type i interferon productionGO:0032606290.184
Mouse
cellular response to lipidGO:00713961450.182
nucleoside phosphate metabolic processGO:00067533380.163
regulation of innate immune responseGO:0045088910.163
protein modification by small protein conjugationGO:00324461870.147
Mouse
cellular response to molecule of bacterial originGO:0071219830.147
regulation of protein targetingGO:1903533610.147
Mouse
nucleotide metabolic processGO:00091173320.141
negative regulation of phosphorylationGO:00423261660.136
Mouse
regulation of defense response to virusGO:0050688180.129
Mouse
cytoplasmic transportGO:00164822340.128
Mouse
regulation of interferon alpha productionGO:003264750.123
Mouse
intracellular protein transportGO:00068862040.118
Mouse
activation of innate immune responseGO:0002218560.117
regulation of protein localizationGO:00328802310.114
Mouse
organic cyclic compound catabolic processGO:19013612950.104
negative regulation of protein metabolic processGO:00512482820.101
Mouse
purine ribonucleoside catabolic processGO:00461302050.101
regulation of intracellular protein transportGO:0033157820.100
Mouse
regulation of nucleocytoplasmic transportGO:0046822730.098
Mouse
positive regulation of defense responseGO:00313491240.095
nucleoside phosphate catabolic processGO:19012922220.094
regulation of establishment of protein localizationGO:00702011810.092
Mouse
negative regulation of intracellular transportGO:0032387380.089
Mouse
establishment of protein localization to organelleGO:00725941180.088
Mouse
negative regulation of cytoplasmic transportGO:1903650290.087
Mouse
nucleocytoplasmic transportGO:00069131390.086
Mouse
purine containing compound metabolic processGO:00725213110.085
regulation of cytoplasmic transportGO:19036491120.083
Mouse
positive regulation of cytokine productionGO:00018191740.079
single organism nuclear importGO:1902593950.076
Mouse
organophosphate catabolic processGO:00464342320.073
regulation of protein modification by small protein conjugation or removalGO:1903320570.073
Mouse
interspecies interaction between organismsGO:0044419830.072
activation of immune responseGO:00022531380.071
gtp catabolic processGO:00061841430.071
nucleoside triphosphate catabolic processGO:00091432050.071
ribonucleoside catabolic processGO:00424542060.071
regulation of protein ubiquitinationGO:0031396520.068
Mouse
nucleotide catabolic processGO:00091662170.068
ribonucleoside triphosphate metabolic processGO:00091992200.067
purine nucleoside catabolic processGO:00061522050.066
purine ribonucleotide catabolic processGO:00091542080.065
organonitrogen compound catabolic processGO:19015652640.065
nucleobase containing small molecule metabolic processGO:00550863520.065
cellular response to cytokine stimulusGO:00713451890.065
myeloid leukocyte differentiationGO:00025731190.064
regulation of reactive oxygen species metabolic processGO:2000377400.064
cellular amino acid metabolic processGO:00065201030.063
protein targetingGO:00066051430.061
Mouse
immune response activating signal transductionGO:00027571160.061
ribonucleotide metabolic processGO:00092592910.060
carbohydrate derivative catabolic processGO:19011362310.056
cellular nitrogen compound catabolic processGO:00442702800.056
purine containing compound catabolic processGO:00725232130.055
purine ribonucleoside triphosphate metabolic processGO:00092052200.055
nucleoside triphosphate metabolic processGO:00091412300.055
negative regulation of protein transportGO:0051224460.054
Mouse
glycosyl compound metabolic processGO:19016572460.054
glycosyl compound catabolic processGO:19016582060.053
innate immune response activating signal transductionGO:0002758500.053
purine nucleoside triphosphate catabolic processGO:00091462030.052
nucleoside catabolic processGO:00091642060.052
reactive oxygen species metabolic processGO:0072593840.052
ribonucleoside triphosphate catabolic processGO:00092031990.052
aromatic compound catabolic processGO:00194392860.051
nuclear importGO:0051170950.050
Mouse
guanosine containing compound catabolic processGO:19010691440.050
guanosine containing compound metabolic processGO:19010681440.050
regulation of protein localization to nucleusGO:1900180600.050
Mouse
ribonucleotide catabolic processGO:00092612080.050
negative regulation of phosphorus metabolic processGO:00105631840.049
Mouse
nucleoside metabolic processGO:00091162460.048
leukocyte differentiationGO:00025213420.047
nuclear transportGO:00511691390.046
Mouse
negative regulation of cell proliferationGO:00082852960.046
negative regulation of nucleocytoplasmic transportGO:0046823230.045
Mouse
cation transportGO:00068123990.044
rig i signaling pathwayGO:003952940.044
cellular amine metabolic processGO:0044106440.043
regulation of defense response to bacteriumGO:190042430.042
negative regulation of immune system processGO:00026832090.041
positive regulation of innate immune responseGO:0045089800.040
purine nucleoside metabolic processGO:00422782410.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.037
purine ribonucleoside triphosphate catabolic processGO:00092071990.037
regulation of cellular amino acid metabolic processGO:000652150.036
immune response regulating signaling pathwayGO:00027641250.036
purine nucleoside triphosphate metabolic processGO:00091442260.036
negative regulation of defense responseGO:0031348770.036
ribose phosphate metabolic processGO:00196932910.036
regulation of hydrolase activityGO:00513362460.035
muscle tissue developmentGO:00605373080.035
regulation of cellular ketone metabolic processGO:0010565660.035
regulation of lymphocyte activationGO:00512492400.035
response to organic cyclic compoundGO:00140701980.034
negative regulation of cellular component organizationGO:00511291940.034
purine ribonucleotide metabolic processGO:00091502900.034
regulation of autophagyGO:0010506300.032
regulation of viral genome replicationGO:0045069130.032
mapk cascadeGO:00001652810.032
regulation of protein import into nucleusGO:0042306520.032
Mouse
positive regulation of viral genome replicationGO:004507020.031
myeloid cell differentiationGO:00300992330.031
regulation of lymphocyte proliferationGO:00506701170.031
negative regulation of protein modification processGO:00314001630.030
Mouse
autophagyGO:0006914450.030
purine nucleotide catabolic processGO:00061952110.028
regulation of proteolysisGO:00301621640.028
apoptotic signaling pathwayGO:00971903060.028
regulation of cellular amine metabolic processGO:0033238200.028
heterocycle catabolic processGO:00467002800.028
negative regulation of molecular functionGO:00440922580.028
negative regulation of protein modification by small protein conjugation or removalGO:1903321200.027
Mouse
inflammatory responseGO:00069542440.027
positive regulation of cell killingGO:0031343330.027
cellular response to organonitrogen compoundGO:00714171450.026
pattern recognition receptor signaling pathwayGO:0002221470.026
regulation of cellular component biogenesisGO:00440871810.026
gland developmentGO:00487323300.026
leukocyte proliferationGO:00706611720.026
positive regulation of rig i signaling pathwayGO:190024610.025
homeostasis of number of cellsGO:00488722100.025
ossificationGO:00015032160.025
cellular ketone metabolic processGO:0042180840.025
regulation of endopeptidase activityGO:0052548890.025
purine nucleotide metabolic processGO:00061633020.025
protein importGO:00170381010.025
Mouse
response to lipopolysaccharideGO:00324961280.024
positive regulation of reactive oxygen species biosynthetic processGO:190342820.024
cellular lipid metabolic processGO:00442553230.024
t cell activationGO:00421102890.024
regulation of interleukin 4 biosynthetic processGO:004540230.024
cell type specific apoptotic processGO:00972852680.023
lymphocyte differentiationGO:00300982420.023
carbohydrate metabolic processGO:00059752300.023
protein processingGO:00164851630.023
regulation of peptidase activityGO:0052547960.023
t cell differentiationGO:00302171740.023
positive regulation of viral entry into host cellGO:004659830.023
regulation of inflammatory responseGO:00507271470.023
amine metabolic processGO:0009308450.022
positive regulation of peptidase activityGO:0010952490.022
positive regulation of interferon alpha productionGO:003272740.022
regulation of cellular catabolic processGO:00313292420.022
actin cytoskeleton organizationGO:00300362200.022
regulation of cell cycleGO:00517262810.022
viral life cycleGO:0019058360.022
negative regulation of cell developmentGO:00107211690.022
regulation of t cell activationGO:00508631700.022
peptidyl amino acid modificationGO:00181933360.021
leukocyte mediated immunityGO:00024431740.021
response to organonitrogen compoundGO:00102432460.021
regulation of hormone levelsGO:00108172110.021
negative regulation of protein import into nucleusGO:0042308210.021
Mouse
blood vessel morphogenesisGO:00485142850.021
purine ribonucleoside metabolic processGO:00461282410.021
regulation of leukocyte differentiationGO:19021051590.021
leukocyte mediated cytotoxicityGO:0001909620.020
dna metabolic processGO:00062593030.020
angiogenesisGO:00015252010.020
nitrogen compound transportGO:00717052710.020
modification dependent macromolecule catabolic processGO:00436321330.020
regulation of organelle organizationGO:00330432890.020
defense response to gram negative bacteriumGO:0050829280.020
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.020
negative regulation of nervous system developmentGO:00519611560.020
maintenance of locationGO:0051235890.020
mitotic cell cycleGO:00002781950.020
negative regulation of defense response to virus by hostGO:005068910.020
cellular homeostasisGO:00197252400.020
positive regulation of lymphocyte activationGO:00512511400.019
negative regulation of viral processGO:0048525230.019
interferon alpha productionGO:003260770.019
Mouse
protein import into nucleusGO:0006606950.019
Mouse
protein maturationGO:00516041760.019
transmembrane transportGO:00550854120.019
macromolecule catabolic processGO:00090572810.019
cellular macromolecule catabolic processGO:00442652060.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
positive regulation of type i interferon mediated signaling pathwayGO:006034040.018
cytokine mediated signaling pathwayGO:00192211150.018
small gtpase mediated signal transductionGO:0007264970.018
negative regulation of multi organism processGO:0043901680.018
viral processGO:0016032410.018
protein catabolic processGO:00301632210.018
regulation of rig i signaling pathwayGO:003953520.018
modification dependent protein catabolic processGO:00199411330.018
positive regulation of immune effector processGO:00026991070.018
b cell activationGO:00421131610.018
regulation of nlrp3 inflammasome complex assemblyGO:190022540.018
production of molecular mediator of immune responseGO:00024401030.018
ribonucleoside metabolic processGO:00091192450.018
viral gene expressionGO:001908030.018
positive regulation of reactive oxygen species metabolic processGO:2000379110.017
regulation of cell killingGO:0031341400.017
regulation of protein maturationGO:1903317960.017
regulation of response to woundingGO:19030341890.017
gtp metabolic processGO:00460391440.017
cellular ion homeostasisGO:00068731650.017
response to peptideGO:19016521360.016
renal system developmentGO:00720012250.016
protein localization to organelleGO:00333651850.016
Mouse
positive regulation of cell deathGO:00109422240.016
lymphocyte proliferationGO:00466511640.016
leukocyte homeostasisGO:0001776790.016
syncytium formation by plasma membrane fusionGO:0000768420.016
t cell proliferationGO:00420981200.016
taurine metabolic processGO:001953040.016
cellular response to dna damage stimulusGO:00069742070.016
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.016
positive regulation of cellular amine metabolic processGO:003324050.016
striated muscle tissue developmentGO:00147062930.016
negative regulation of proteolysisGO:0045861740.016
negative regulation of innate immune responseGO:0045824170.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
skeletal muscle organ developmentGO:00605381630.016
sensory perceptionGO:00076002450.015
regulation of secretionGO:00510462740.015
viral transcriptionGO:001908330.015
regulation of lymphocyte differentiationGO:00456191070.015
ras protein signal transductionGO:0007265770.015
positive regulation of programmed cell deathGO:00430682180.015
regulation of neutrophil mediated killing of gram negative bacteriumGO:007095110.015
stem cell differentiationGO:00488632680.015
positive regulation of protein modification processGO:00314012990.015
peptidyl tyrosine phosphorylationGO:00181081430.015
protein localization to nucleusGO:00345041210.015
Mouse
regulation of body fluid levelsGO:00508781620.015
regulation of mapk cascadeGO:00434082480.015
cellular response to hormone stimulusGO:00328701500.015
positive regulation of killing of cells of other organismGO:005171230.015
regulation of cell migrationGO:00303342190.015
rho protein signal transductionGO:0007266320.015
positive regulation of adaptive immune responseGO:0002821610.015
positive regulation of lymphocyte mediated immunityGO:0002708620.015
cellular response to interferon alphaGO:003545740.015
erythrocyte differentiationGO:0030218880.015
anion transportGO:00068201770.014
regulation of kinase activityGO:00435492490.014
toll like receptor signaling pathwayGO:0002224380.014
cation homeostasisGO:00550802120.014
interleukin 2 biosynthetic processGO:0042094150.014
regulation of actin nucleationGO:005112540.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
regulation of multi organism processGO:00439001110.014
Mouse
regulation of cytokine biosynthetic processGO:0042035590.014
metal ion homeostasisGO:00550651890.014
positive regulation of mapk cascadeGO:00434101700.014
rna interferenceGO:001624620.014
programmed necrotic cell deathGO:0097300280.014
organophosphate biosynthetic processGO:00904071220.014
cell adhesionGO:00071553290.014
cellular metal ion homeostasisGO:00068751510.014
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.014
urogenital system developmentGO:00016552610.013
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.013
muscle cell differentiationGO:00426922610.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
negative regulation of hydrolase activityGO:0051346710.013
regulation of natural killer cell mediated cytotoxicityGO:0042269190.013
regulation of leukocyte proliferationGO:00706631210.013
ion transmembrane transportGO:00342203610.013
regulation of interferon gamma productionGO:0032649570.013
regulation of anatomical structure sizeGO:00900661780.013
carbohydrate derivative biosynthetic processGO:19011371830.013
reactive oxygen species biosynthetic processGO:190340980.013
positive regulation of protein phosphorylationGO:00019342420.013
regulation of lipid metabolic processGO:00192161180.013
positive regulation of leukocyte proliferationGO:0070665730.013
inorganic cation transmembrane transportGO:00986622070.013
organic hydroxy compound metabolic processGO:19016152030.013
syncytium formationGO:0006949430.013
inorganic ion transmembrane transportGO:00986602340.013
histone modificationGO:00165701590.013
mitotic cell cycle processGO:19030471590.013
reactive nitrogen species metabolic processGO:200105700.013
cellular protein complex assemblyGO:00436231160.013
striated muscle cell developmentGO:00550021250.013
muscle cell developmentGO:00550011330.013
amide transportGO:00428861380.013
regulation of mitotic cell cycle phase transitionGO:1901990730.013
negative regulation of cell cycleGO:00457861230.013
positive regulation of apoptotic processGO:00430652170.013
cellular chemical homeostasisGO:00550822150.013
negative regulation of viral transcriptionGO:003289730.013
male gamete generationGO:00482322850.013
alpha beta t cell activationGO:0046631910.012
epithelial tube morphogenesisGO:00605623030.012
regulation of protein processingGO:0070613960.012
regulation of defense response to virus by hostGO:005069180.012
forebrain developmentGO:00309003020.012
regulation of leukocyte mediated immunityGO:00027031040.012
cation transmembrane transportGO:00986552660.012
positive regulation of proteolysisGO:0045862850.012
limb morphogenesisGO:00351081490.012
calcium ion transportGO:00068161590.012
multicellular organismal homeostasisGO:00488711640.012
regulation of purine nucleotide metabolic processGO:19005421690.012
sequestering of calcium ionGO:0051208180.012
cellular protein catabolic processGO:00442571550.012
carbohydrate homeostasisGO:00335001280.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.012
protein secretionGO:00093061110.012
g protein coupled receptor signaling pathwayGO:00071862430.012
glucose homeostasisGO:00425931280.012
myeloid cell homeostasisGO:00022621140.012
superoxide metabolic processGO:0006801270.012
hormone metabolic processGO:0042445860.012
germ cell developmentGO:00072811850.012
regulation of leukocyte mediated cytotoxicityGO:0001910380.012
positive regulation of endopeptidase activityGO:0010950430.012
regulation of purine nucleotide catabolic processGO:00331211220.012
regulation of cell adhesionGO:00301551540.012
cell activation involved in immune responseGO:00022631260.012
positive regulation of t cell activationGO:00508701010.012
chromatin organizationGO:00063252060.012
response to peptide hormoneGO:00434341270.012
positive regulation of cell activationGO:00508671580.011
response to radiationGO:00093141650.011
negative regulation of protein processingGO:0010955790.011
divalent inorganic cation homeostasisGO:00725071380.011
regulation of interleukin 10 secretionGO:200117940.011
methylationGO:00322591340.011
lymphocyte activation involved in immune responseGO:0002285930.011
regulation of protein catabolic processGO:00421761080.011
actin filament organizationGO:00070151130.011
lipopolysaccharide mediated signaling pathwayGO:0031663250.011
cell cycle g1 s phase transitionGO:0044843570.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
interleukin 10 secretionGO:007260840.011
myotube differentiationGO:00149021050.011
ubiquitin dependent protein catabolic processGO:00065111290.011
positive regulation of lymphocyte differentiationGO:0045621610.011
extracellular structure organizationGO:00430621480.011
antimicrobial peptide biosynthetic processGO:000277720.011
sequestering of metal ionGO:0051238190.011
natural killer cell proliferationGO:000178730.011
regulation of secretion by cellGO:19035302490.011
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.011
cellular carbohydrate metabolic processGO:00442621190.011
regulation of lymphocyte mediated immunityGO:0002706840.011
stem cell developmentGO:00488642190.011
positive regulation of leukocyte differentiationGO:1902107860.011
regulation of transferase activityGO:00513382630.011
immunoglobulin mediated immune responseGO:0016064690.011
i kappab kinase nf kappab signalingGO:0007249850.011
negative regulation of intracellular signal transductionGO:19025321670.011
negative regulation of viral genome replicationGO:0045071100.011
tube formationGO:00351481400.011
regulation of cell activationGO:00508652890.011
positive regulation of actin nucleationGO:005112730.011
neutrophil mediated killing of gram negative bacteriumGO:007094540.011
regulation of interleukin 2 productionGO:0032663280.011
regulation of neuron differentiationGO:00456642810.010
regulation of ossificationGO:00302781120.010
regulation of nucleotide metabolic processGO:00061401690.010
limb developmentGO:00601731660.010
regulation of adaptive immune responseGO:0002819900.010
posttranscriptional regulation of gene expressionGO:00106081550.010
anatomical structure homeostasisGO:00602491450.010
peptidyl tyrosine modificationGO:00182121450.010
regulation of cellular carbohydrate metabolic processGO:0010675750.010
positive regulation of interleukin 10 secretionGO:200118110.010
hormone secretionGO:00468791280.010
negative regulation of cellular amine metabolic processGO:003323910.010
organonitrogen compound biosynthetic processGO:19015661920.010
regulation of epithelial cell proliferationGO:00506781410.010
glial cell differentiationGO:00100011310.010
positive regulation of nucleotide metabolic processGO:00459811140.010
regulation of viral transcriptionGO:004678230.010
skeletal system developmentGO:00015013560.010
antimicrobial peptide productionGO:000277520.010
positive regulation of cellular component biogenesisGO:0044089940.010

Gbp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
immune system diseaseDOID:291400.019
musculoskeletal system diseaseDOID:1700.015
disease of metabolismDOID:001466700.010