| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.390 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.176 | |
| protein ubiquitination | GO:0016567 | 171 | 0.155 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.125 | |
| protein catabolic process | GO:0030163 | 221 | 0.110 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.103 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.087 | |
| male gamete generation | GO:0048232 | 285 | 0.085 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.075 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.071 | |
| synaptic transmission | GO:0007268 | 329 | 0.060 | |
| cation transport | GO:0006812 | 399 | 0.056 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.055 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.054 | |
| transmembrane transport | GO:0055085 | 412 | 0.051 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.049 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.047 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.047 | |
| organelle fission | GO:0048285 | 170 | 0.046 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.046 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.046 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.045 | |
| spermatogenesis | GO:0007283 | 284 | 0.042 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.041 | |
| telencephalon development | GO:0021537 | 186 | 0.040 | |
| regulation of protein localization | GO:0032880 | 231 | 0.040 | |
| cellularization | GO:0007349 | 1 | 0.039 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.039 | |
| organic acid transport | GO:0015849 | 101 | 0.039 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.039 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.038 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.036 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.036 | |
| muscle tissue development | GO:0060537 | 308 | 0.036 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.035 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.035 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.035 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.034 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.034 | |
| endomembrane system organization | GO:0010256 | 147 | 0.034 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.034 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.033 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.033 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.033 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.032 | |
| protein neddylation | GO:0045116 | 1 | 0.032 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.032 | |
| dna metabolic process | GO:0006259 | 303 | 0.032 | |
| translational initiation | GO:0006413 | 24 | 0.031 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.031 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.030 | |
| mitochondrion organization | GO:0007005 | 134 | 0.030 | |
| mitochondrion distribution | GO:0048311 | 4 | 0.030 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.030 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.030 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.029 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.028 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.028 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.028 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.027 | |
| microtubule organizing center organization | GO:0031023 | 28 | 0.026 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.026 | |
| protein deubiquitination | GO:0016579 | 19 | 0.026 | |
| synapse organization | GO:0050808 | 125 | 0.025 | |
| cellular homeostasis | GO:0019725 | 240 | 0.025 | |
| intracellular distribution of mitochondria | GO:0048312 | 1 | 0.025 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.025 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.025 | |
| negative regulation of ligase activity | GO:0051352 | 3 | 0.024 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.024 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.024 | |
| gtp metabolic process | GO:0046039 | 144 | 0.024 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.024 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.024 | |
| protein localization to membrane | GO:0072657 | 108 | 0.023 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.023 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.023 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.023 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.023 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.023 | |
| microtubule based process | GO:0007017 | 236 | 0.023 | |
| anion transport | GO:0006820 | 177 | 0.022 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.022 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 70 | 0.022 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.022 | |
| cell adhesion | GO:0007155 | 329 | 0.022 | |
| positive regulation of fibroblast growth factor receptor signaling pathway | GO:0045743 | 3 | 0.022 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.022 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.022 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.022 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.022 | |
| regulation of protein processing | GO:0070613 | 96 | 0.021 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.021 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.021 | |
| l amino acid transport | GO:0015807 | 32 | 0.021 | |
| learning or memory | GO:0007611 | 148 | 0.021 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.021 | |
| regulation of mitochondrial fission | GO:0090140 | 3 | 0.021 | |
| amp metabolic process | GO:0046033 | 4 | 0.021 | |
| regulation of secretion | GO:0051046 | 274 | 0.021 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.021 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.021 | |
| regulation of ion transport | GO:0043269 | 215 | 0.021 | |
| dendrite development | GO:0016358 | 115 | 0.020 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.020 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.020 | |
| positive regulation of neuron projection development | GO:0010976 | 79 | 0.020 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.020 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.019 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.019 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.019 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.019 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.019 | |
| endocytosis | GO:0006897 | 168 | 0.019 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.019 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.019 | |
| protein secretion | GO:0009306 | 111 | 0.019 | |
| nuclear division | GO:0000280 | 158 | 0.018 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.018 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.018 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.018 | |
| dna repair | GO:0006281 | 107 | 0.018 | |
| organic anion transport | GO:0015711 | 137 | 0.018 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.018 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.017 | |
| forebrain development | GO:0030900 | 302 | 0.017 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.017 | |
| positive regulation of long term neuronal synaptic plasticity | GO:0048170 | 3 | 0.017 | |
| neuron projection guidance | GO:0097485 | 141 | 0.017 | |
| memory | GO:0007613 | 58 | 0.017 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.017 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.017 | |
| mitochondrial fragmentation involved in apoptotic process | GO:0043653 | 1 | 0.017 | |
| membrane organization | GO:0061024 | 245 | 0.017 | |
| establishment of melanosome localization | GO:0032401 | 11 | 0.016 | |
| nucleobase containing compound transport | GO:0015931 | 27 | 0.016 | |
| chromatin modification | GO:0016568 | 187 | 0.016 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.016 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.016 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.016 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.016 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.016 | |
| regulation of protein transport | GO:0051223 | 163 | 0.015 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.015 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.015 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.015 | |
| fertilization | GO:0009566 | 127 | 0.015 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.015 | |
| protein localization to organelle | GO:0033365 | 185 | 0.015 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.015 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.015 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.015 | |
| protein glycosylation | GO:0006486 | 55 | 0.015 | |
| maintenance of location | GO:0051235 | 89 | 0.015 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.015 | |
| striated muscle cell development | GO:0055002 | 125 | 0.015 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 25 | 0.014 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.014 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.014 | |
| synapse assembly | GO:0007416 | 56 | 0.014 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.014 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.014 | |
| sensory perception | GO:0007600 | 245 | 0.014 | |
| nuclear dna replication | GO:0033260 | 3 | 0.014 | |
| chemotaxis | GO:0006935 | 247 | 0.014 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.014 | |
| regulation of polysaccharide metabolic process | GO:0032881 | 13 | 0.014 | |
| cognition | GO:0050890 | 149 | 0.014 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.014 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.014 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.014 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.014 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.013 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.013 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.013 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.013 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.013 | |
| plasma membrane organization | GO:0007009 | 90 | 0.013 | |
| oxidation reduction process | GO:0055114 | 342 | 0.013 | |
| cellular polysaccharide catabolic process | GO:0044247 | 5 | 0.013 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.013 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.013 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.013 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.013 | |
| chromatin organization | GO:0006325 | 206 | 0.013 | |
| amino acid transport | GO:0006865 | 61 | 0.013 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.013 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.013 | |
| muscle cell development | GO:0055001 | 133 | 0.013 | |
| camera type eye development | GO:0043010 | 266 | 0.013 | |
| spermatid development | GO:0007286 | 108 | 0.013 | |
| muscle fiber development | GO:0048747 | 76 | 0.013 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.013 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.013 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.012 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.012 | |
| membrane fusion | GO:0061025 | 38 | 0.012 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.012 | |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.012 | |
| positive regulation of mitotic metaphase anaphase transition | GO:0045842 | 2 | 0.012 | |
| response to growth factor | GO:0070848 | 198 | 0.012 | |
| positive regulation of protein secretion | GO:0050714 | 52 | 0.012 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.012 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.012 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.012 | |
| mitochondrion transport along microtubule | GO:0047497 | 3 | 0.012 | |
| protein complex disassembly | GO:0043241 | 40 | 0.012 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.012 | |
| cellular glucan metabolic process | GO:0006073 | 32 | 0.012 | |
| gtp catabolic process | GO:0006184 | 143 | 0.012 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.012 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.012 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.012 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.012 | |
| regulation of glycogen catabolic process | GO:0005981 | 2 | 0.012 | |
| amine metabolic process | GO:0009308 | 45 | 0.012 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.012 | |
| organelle localization | GO:0051640 | 179 | 0.011 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.011 | |
| hippocampus development | GO:0021766 | 52 | 0.011 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.011 | |
| response to inorganic substance | GO:0010035 | 96 | 0.011 | |
| regulation of ubiquitin protein ligase activity involved in mitotic cell cycle | GO:0051439 | 1 | 0.011 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 73 | 0.011 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.011 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.011 | |
| bone development | GO:0060348 | 120 | 0.011 | |
| nuclear transport | GO:0051169 | 139 | 0.011 | |
| reproductive behavior | GO:0019098 | 32 | 0.011 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.011 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.011 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.011 | |
| mapk cascade | GO:0000165 | 281 | 0.011 | |
| lipid localization | GO:0010876 | 126 | 0.011 | |
| protein polymerization | GO:0051258 | 57 | 0.011 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.011 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.011 | |
| positive regulation of phospholipase activity | GO:0010518 | 3 | 0.011 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.011 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.011 | |
| cellular polysaccharide metabolic process | GO:0044264 | 38 | 0.011 | |
| endoplasmic reticulum tubular network organization | GO:0071786 | 1 | 0.011 | |
| mitochondrial transport | GO:0006839 | 36 | 0.011 | |
| long term synaptic potentiation | GO:0060291 | 25 | 0.011 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.011 | |
| regulation of system process | GO:0044057 | 200 | 0.010 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.010 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.010 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.010 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.010 | |
| epithelial cell development | GO:0002064 | 159 | 0.010 | |
| limbic system development | GO:0021761 | 72 | 0.010 | |
| pallium development | GO:0021543 | 120 | 0.010 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.010 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.010 | |
