| activation of nf kappab inducing kinase activity | GO:0007250 | 4 | 1.000 | Human |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.999 | |
| nik nf kappab signaling | GO:0038061 | 14 | 0.996 | Human |
| regulation of transferase activity | GO:0051338 | 263 | 0.996 | |
| regulation of defense response | GO:0031347 | 233 | 0.996 | Fly |
| regulation of kinase activity | GO:0043549 | 249 | 0.995 | |
| jnk cascade | GO:0007254 | 72 | 0.990 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.989 | |
| positive regulation of antimicrobial peptide production | GO:0002225 | 1 | 0.987 | Fly |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.986 | |
| positive regulation of antibacterial peptide biosynthetic process | GO:0006963 | 1 | 0.984 | Fly |
| serine phosphorylation of stat protein | GO:0042501 | 3 | 0.982 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.976 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.970 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.970 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.966 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.965 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.961 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.958 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.944 | |
| digestive system development | GO:0055123 | 200 | 0.943 | Worm |
| endodermal cell fate specification | GO:0001714 | 4 | 0.941 | Worm |
| leukocyte homeostasis | GO:0001776 | 79 | 0.936 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.935 | |
| b cell homeostasis | GO:0001782 | 34 | 0.935 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.935 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.933 | |
| negative regulation of necrotic cell death | GO:0060547 | 11 | 0.932 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 45 | 0.930 | Human Fly |
| activation of immune response | GO:0002253 | 138 | 0.929 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.924 | Worm |
| cellular protein catabolic process | GO:0044257 | 155 | 0.921 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.914 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.914 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.912 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.906 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.906 | |
| regulation of antibacterial peptide biosynthetic process | GO:0002808 | 1 | 0.902 | Fly |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.897 | |
| antibacterial peptide production | GO:0002778 | 2 | 0.893 | Fly |
| cell cycle switching | GO:0060184 | 1 | 0.888 | |
| defense response to other organism | GO:0098542 | 197 | 0.881 | Fly |
| activation of innate immune response | GO:0002218 | 56 | 0.876 | |
| immune effector process | GO:0002252 | 321 | 0.874 | Human Fly |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.870 | |
| regulation of nik nf kappab signaling | GO:1901222 | 10 | 0.866 | Human |
| dna metabolic process | GO:0006259 | 303 | 0.865 | |
| negative regulation of defense response | GO:0031348 | 77 | 0.864 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.851 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.851 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.849 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.833 | Human |
| negative regulation of necroptotic process | GO:0060546 | 9 | 0.830 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.830 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.829 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.821 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.815 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.815 | |
| interleukin 1 mediated signaling pathway | GO:0070498 | 4 | 0.811 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.806 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 64 | 0.800 | |
| response to oxidative stress | GO:0006979 | 123 | 0.799 | |
| positive regulation of neuron death | GO:1901216 | 28 | 0.795 | |
| regulation of necrotic cell death | GO:0010939 | 13 | 0.794 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.784 | |
| mapk cascade | GO:0000165 | 281 | 0.782 | |
| t cell activation | GO:0042110 | 289 | 0.776 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.766 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 30 | 0.761 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 48 | 0.750 | |
| germline cell cycle switching mitotic to meiotic cell cycle | GO:0051729 | 1 | 0.749 | |
| innate immune response | GO:0045087 | 157 | 0.745 | |
| peptidyl threonine phosphorylation | GO:0018107 | 31 | 0.743 | |
| positive regulation of nik nf kappab signaling | GO:1901224 | 7 | 0.743 | Human |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.738 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.735 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.723 | |
| positive regulation of jnk cascade | GO:0046330 | 46 | 0.723 | |
| cytokine production | GO:0001816 | 319 | 0.722 | Human |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.722 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.721 | |
| striated muscle contraction | GO:0006941 | 45 | 0.720 | |
| nephrogenic mesenchyme morphogenesis | GO:0072134 | 2 | 0.706 | |
| positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | GO:1902043 | 13 | 0.701 | |
| protein import into nucleus | GO:0006606 | 95 | 0.697 | |
| muscle system process | GO:0003012 | 141 | 0.695 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.694 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.692 | Human |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.690 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.685 | |
| transmembrane transport | GO:0055085 | 412 | 0.683 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.679 | |
| regulation of jun kinase activity | GO:0043506 | 40 | 0.661 | Human Fly |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.651 | |
| epithelial tube formation | GO:0072175 | 130 | 0.649 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 30 | 0.645 | |
| positive regulation of jun kinase activity | GO:0043507 | 30 | 0.642 | Human Fly |
| mammary gland lobule development | GO:0061377 | 22 | 0.637 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.636 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.631 | |
| cell cycle switching mitotic to meiotic cell cycle | GO:0051728 | 1 | 0.626 | |
| negative regulation of b cell activation | GO:0050869 | 27 | 0.622 | |
| regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway | GO:1902235 | 11 | 0.619 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.608 | Human |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.607 | |
| amine metabolic process | GO:0009308 | 45 | 0.602 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.601 | |
| programmed necrotic cell death | GO:0097300 | 28 | 0.600 | |
| cell fate commitment | GO:0045165 | 210 | 0.591 | Worm |
| peptidyl threonine modification | GO:0018210 | 31 | 0.590 | |
| regulation of transforming growth factor beta receptor signaling pathway | GO:0017015 | 43 | 0.585 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.585 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.583 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.582 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.574 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.573 | Human |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.571 | |
| endoderm development | GO:0007492 | 45 | 0.567 | Worm |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.562 | |
| negative regulation of lymphocyte proliferation | GO:0050672 | 45 | 0.561 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.556 | |
| positive regulation of cell proliferation involved in heart valve morphogenesis | GO:0003251 | 1 | 0.553 | |
| digestive tract development | GO:0048565 | 190 | 0.552 | Worm |
| cytokine production involved in immune response | GO:0002367 | 34 | 0.551 | Human |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.549 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 59 | 0.549 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.548 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.546 | |
| bmp signaling pathway | GO:0030509 | 93 | 0.542 | |
| trunk segmentation | GO:0035290 | 4 | 0.539 | |
| necrotic cell death | GO:0070265 | 30 | 0.538 | |
| protein ubiquitination | GO:0016567 | 171 | 0.537 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.537 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 26 | 0.535 | Human |
| respiratory system development | GO:0060541 | 190 | 0.532 | |
| response to growth factor | GO:0070848 | 198 | 0.531 | |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.524 | |
| regulation of necroptotic process | GO:0060544 | 10 | 0.523 | |
| ripoptosome assembly involved in necroptotic process | GO:1901026 | 6 | 0.522 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.520 | |
| gastrulation | GO:0007369 | 116 | 0.516 | Worm |
| primary neural tube formation | GO:0014020 | 95 | 0.513 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.509 | |
| muscle contraction | GO:0006936 | 101 | 0.503 | |
| chromatin organization | GO:0006325 | 206 | 0.501 | Human |
| positive regulation of protein import into nucleus | GO:0042307 | 26 | 0.498 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.498 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.497 | |
| regulation of smad protein import into nucleus | GO:0060390 | 3 | 0.493 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.490 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.490 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.489 | |
| endodermal cell fate commitment | GO:0001711 | 12 | 0.489 | Worm |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.484 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.478 | |
| protein k63 linked ubiquitination | GO:0070534 | 6 | 0.473 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.471 | |
| germ line stem cell division | GO:0042078 | 2 | 0.468 | |
| cardiocyte differentiation | GO:0035051 | 87 | 0.464 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.463 | |
| interleukin 6 production | GO:0032635 | 58 | 0.455 | |
| gland development | GO:0048732 | 330 | 0.447 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.441 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.441 | |
| interferon beta biosynthetic process | GO:0045350 | 4 | 0.437 | |
| interferon beta production | GO:0032608 | 16 | 0.435 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.434 | |
| myeloid dendritic cell activation | GO:0001773 | 25 | 0.426 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.423 | |
| i kappab phosphorylation | GO:0007252 | 6 | 0.422 | |
| muscle tissue development | GO:0060537 | 308 | 0.420 | |
| bone development | GO:0060348 | 120 | 0.420 | |
| cell proliferation involved in heart valve development | GO:2000793 | 2 | 0.418 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.417 | |
| response to tumor necrosis factor | GO:0034612 | 26 | 0.413 | |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 61 | 0.412 | Human |
| positive regulation of defense response | GO:0031349 | 124 | 0.406 | Fly |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.404 | Human |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.404 | |
| protein catabolic process | GO:0030163 | 221 | 0.403 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.400 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.392 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.391 | |
| inflammatory response | GO:0006954 | 244 | 0.387 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.384 | |
| neural tube development | GO:0021915 | 160 | 0.384 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.384 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 25 | 0.381 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.378 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 34 | 0.368 | |
| cellular response to lipid | GO:0071396 | 145 | 0.367 | Fly |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.365 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.363 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.361 | |
| neural tube closure | GO:0001843 | 90 | 0.360 | |
| limb morphogenesis | GO:0035108 | 149 | 0.353 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.353 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.352 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.352 | |
| regulation of bmp signaling pathway | GO:0030510 | 60 | 0.345 | |
| endocardial cell differentiation | GO:0060956 | 4 | 0.345 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.341 | |
| toll like receptor signaling pathway | GO:0002224 | 38 | 0.341 | |
| positive regulation of synaptic growth at neuromuscular junction | GO:0045887 | 1 | 0.338 | |
| urogenital system development | GO:0001655 | 261 | 0.336 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.336 | |
| respiratory tube development | GO:0030323 | 167 | 0.336 | |
| response to oxygen levels | GO:0070482 | 62 | 0.334 | |
| hepaticobiliary system development | GO:0061008 | 67 | 0.329 | |
| positive regulation of lymphocyte mediated immunity | GO:0002708 | 62 | 0.325 | Human |
| nitrogen compound transport | GO:0071705 | 271 | 0.322 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.319 | |
| neuron death | GO:0070997 | 154 | 0.319 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 82 | 0.314 | |
| mitochondrion organization | GO:0007005 | 134 | 0.306 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.302 | |
| pathway restricted smad protein phosphorylation | GO:0060389 | 10 | 0.299 | |
| cellular response to tumor necrosis factor | GO:0071356 | 21 | 0.298 | |
| defense response to bacterium | GO:0042742 | 119 | 0.296 | Fly |
| regulation of interferon beta biosynthetic process | GO:0045357 | 4 | 0.293 | |
| nephrogenic mesenchyme development | GO:0072076 | 3 | 0.292 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.291 | |
| odontogenesis | GO:0042476 | 78 | 0.291 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 26 | 0.287 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.287 | |
| neural tube formation | GO:0001841 | 108 | 0.287 | |
| rhythmic process | GO:0048511 | 174 | 0.287 | |
| skeletal system development | GO:0001501 | 356 | 0.287 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.286 | |
| positive regulation of interleukin 2 production | GO:0032743 | 19 | 0.286 | Human |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.285 | |
| convergent extension | GO:0060026 | 14 | 0.282 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.278 | |
| positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus | GO:1901522 | 7 | 0.275 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.273 | Human Fly |
| dendritic cell proliferation | GO:0044565 | 2 | 0.272 | |
| b cell proliferation | GO:0042100 | 53 | 0.269 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.268 | Human |
| t cell receptor signaling pathway | GO:0050852 | 46 | 0.266 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.265 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.263 | |
| negative regulation of interleukin 5 production | GO:0032714 | 4 | 0.261 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.259 | |
| connective tissue development | GO:0061448 | 179 | 0.258 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 30 | 0.258 | |
| regulation of cell activation | GO:0050865 | 289 | 0.257 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.256 | Human Fly |
| response to uv | GO:0009411 | 44 | 0.255 | |
| tube closure | GO:0060606 | 91 | 0.254 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.252 | |
| regulation of defense response to virus | GO:0050688 | 18 | 0.249 | |
| heart growth | GO:0060419 | 45 | 0.248 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.247 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.246 | |
| interleukin 6 biosynthetic process | GO:0042226 | 12 | 0.245 | |
| positive regulation of smad protein import into nucleus | GO:0060391 | 2 | 0.243 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.243 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.242 | |
| heart morphogenesis | GO:0003007 | 178 | 0.241 | |
| t cell proliferation | GO:0042098 | 120 | 0.241 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.240 | |
| regulation of defense response to bacterium | GO:1900424 | 3 | 0.240 | Fly |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.236 | |
| brainstem development | GO:0003360 | 3 | 0.236 | |
| regulation of transporter activity | GO:0032409 | 57 | 0.235 | |
| type i interferon production | GO:0032606 | 29 | 0.231 | |
| epithelial to mesenchymal transition involved in endocardial cushion formation | GO:0003198 | 10 | 0.229 | |
| lung development | GO:0030324 | 164 | 0.228 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.227 | |
| response to inorganic substance | GO:0010035 | 96 | 0.226 | |
| positive regulation of defense response to bacterium | GO:1900426 | 1 | 0.226 | Fly |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.224 | |
| regulation of neuron death | GO:1901214 | 134 | 0.223 | |
| axonogenesis | GO:0007409 | 274 | 0.222 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.220 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.219 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.218 | Human |
| nuclear import | GO:0051170 | 95 | 0.217 | |
| cardiac muscle tissue development | GO:0048738 | 130 | 0.217 | |
| hair follicle development | GO:0001942 | 85 | 0.216 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.216 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.213 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.213 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.211 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 15 | 0.209 | |
| tumor necrosis factor mediated signaling pathway | GO:0033209 | 13 | 0.209 | |
| segmentation | GO:0035282 | 93 | 0.208 | |
| embryonic skeletal system development | GO:0048706 | 120 | 0.205 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.204 | |
| myeloid dendritic cell differentiation | GO:0043011 | 16 | 0.203 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.201 | |
| kidney mesenchyme morphogenesis | GO:0072131 | 4 | 0.201 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.200 | |
| positive regulation of cytokine production involved in immune response | GO:0002720 | 19 | 0.197 | Human |
| cytokine metabolic process | GO:0042107 | 71 | 0.196 | |
| regulation of interferon beta production | GO:0032648 | 13 | 0.196 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.196 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.192 | Fly |
| jak stat cascade | GO:0007259 | 42 | 0.192 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.191 | |
| regulation of protein deacetylation | GO:0090311 | 17 | 0.190 | |
| endothelial cell activation | GO:0042118 | 1 | 0.188 | |
| positive regulation of osteoclast differentiation | GO:0045672 | 15 | 0.188 | |
| cell proliferation involved in heart valve morphogenesis | GO:0003249 | 1 | 0.187 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 49 | 0.186 | |
| cation transport | GO:0006812 | 399 | 0.185 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.183 | |
| cardiac ventricle development | GO:0003231 | 83 | 0.182 | |
| protein import | GO:0017038 | 101 | 0.182 | |
| positive regulation of immature t cell proliferation | GO:0033091 | 4 | 0.181 | |
| cellular response to reactive nitrogen species | GO:1902170 | 5 | 0.181 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.179 | Fly |
| regulation of interleukin 2 production | GO:0032663 | 28 | 0.179 | Human |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.178 | Human |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.178 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.178 | |
| negative regulation of response to endoplasmic reticulum stress | GO:1903573 | 8 | 0.177 | |
| activation of mapkkk activity | GO:0000185 | 1 | 0.175 | |
| stem cell maintenance | GO:0019827 | 130 | 0.175 | |
| lens development in camera type eye | GO:0002088 | 62 | 0.174 | |
| striated muscle cell proliferation | GO:0014855 | 39 | 0.173 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.173 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.173 | |
| regulation of system process | GO:0044057 | 200 | 0.172 | |
| odontogenesis of dentin containing tooth | GO:0042475 | 66 | 0.170 | |
| activation induced cell death of t cells | GO:0006924 | 10 | 0.169 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.167 | |
| glial cell apoptotic process | GO:0034349 | 3 | 0.167 | |
| regulation of epithelial to mesenchymal transition | GO:0010717 | 22 | 0.167 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.166 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.165 | |
| camera type eye development | GO:0043010 | 266 | 0.165 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.164 | |
| regionalization | GO:0003002 | 337 | 0.162 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.162 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.162 | |
| cell fate specification | GO:0001708 | 72 | 0.159 | Worm |
| regulation of striated muscle contraction | GO:0006942 | 25 | 0.158 | |
| antimicrobial peptide production | GO:0002775 | 2 | 0.156 | Fly |
| regulation of jak stat cascade | GO:0046425 | 34 | 0.155 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.154 | |
| negative regulation of immune effector process | GO:0002698 | 55 | 0.153 | |
| endocardial cushion morphogenesis | GO:0003203 | 18 | 0.153 | |
| cellular response to nitric oxide | GO:0071732 | 4 | 0.153 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.152 | |
| hindbrain development | GO:0030902 | 128 | 0.152 | |
| liver development | GO:0001889 | 66 | 0.151 | |
| nuclear transport | GO:0051169 | 139 | 0.151 | |
| ossification | GO:0001503 | 216 | 0.150 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.149 | |
| muscle cell proliferation | GO:0033002 | 52 | 0.148 | |
| regulation of interleukin 10 secretion | GO:2001179 | 4 | 0.148 | |
| neuron projection guidance | GO:0097485 | 141 | 0.147 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.145 | |
| kidney development | GO:0001822 | 213 | 0.145 | |
| amide transport | GO:0042886 | 138 | 0.144 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.144 | |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.142 | |
| tube formation | GO:0035148 | 140 | 0.142 | |
| intracellular protein transport | GO:0006886 | 204 | 0.142 | |
| protein oligomerization | GO:0051259 | 67 | 0.141 | |
| cell fate commitment involved in formation of primary germ layer | GO:0060795 | 26 | 0.140 | Worm |
| retina development in camera type eye | GO:0060041 | 119 | 0.138 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 39 | 0.138 | |
| immunoglobulin production | GO:0002377 | 73 | 0.137 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.136 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.135 | |
| endocardial cushion formation | GO:0003272 | 13 | 0.135 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.134 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 70 | 0.133 | |
| positive regulation of tolerance induction | GO:0002645 | 8 | 0.132 | |
| somatic stem cell maintenance | GO:0035019 | 47 | 0.130 | |
| lymphocyte apoptotic process | GO:0070227 | 54 | 0.130 | |
| regulation of protein localization | GO:0032880 | 231 | 0.130 | |
| determination of left right symmetry | GO:0007368 | 80 | 0.129 | |
| regulation of lymphocyte anergy | GO:0002911 | 4 | 0.129 | |
| positive regulation of t cell mediated immunity | GO:0002711 | 24 | 0.129 | Human |
| protein targeting | GO:0006605 | 143 | 0.129 | |
| positive regulation of defense response to virus by host | GO:0002230 | 6 | 0.128 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.128 | |
| regulation of sodium ion transport | GO:0002028 | 29 | 0.128 | |
| regulation of heart contraction | GO:0008016 | 77 | 0.127 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.125 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.125 | |
| regulation of b cell proliferation | GO:0030888 | 39 | 0.125 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.124 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.123 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.123 | |
| cell division | GO:0051301 | 120 | 0.123 | Worm |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.123 | |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 35 | 0.123 | |
| antibacterial peptide biosynthetic process | GO:0002780 | 2 | 0.123 | Fly |
| mammary gland epithelial cell proliferation | GO:0033598 | 24 | 0.123 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.123 | |
| negative regulation of peptidyl threonine phosphorylation | GO:0010801 | 6 | 0.122 | |
| chromatin modification | GO:0016568 | 187 | 0.121 | Human |
| positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090100 | 43 | 0.120 | |
| thymus development | GO:0048538 | 41 | 0.120 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.120 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.120 | |
| palate development | GO:0060021 | 76 | 0.119 | |
| regulation of binding | GO:0051098 | 111 | 0.119 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.118 | |
| negative regulation of transforming growth factor beta receptor signaling pathway | GO:0030512 | 26 | 0.117 | |
| ventricular septum morphogenesis | GO:0060412 | 27 | 0.117 | |
| negative regulation of peptidyl serine phosphorylation | GO:0033137 | 10 | 0.117 | |
| regulation of type i interferon production | GO:0032479 | 22 | 0.116 | |
| t cell anergy | GO:0002870 | 4 | 0.115 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.115 | |
| response to radiation | GO:0009314 | 165 | 0.115 | |
| response to peptide | GO:1901652 | 136 | 0.114 | |
| regulation of protein transport | GO:0051223 | 163 | 0.114 | |
| positive regulation of osteoblast differentiation | GO:0045669 | 34 | 0.114 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.113 | Human |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.113 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.113 | |
| defense response to gram negative bacterium | GO:0050829 | 28 | 0.113 | Fly |
| response to peptidoglycan | GO:0032494 | 9 | 0.112 | |
| cartilage development | GO:0051216 | 140 | 0.112 | |
| embryonic heart tube morphogenesis | GO:0003143 | 51 | 0.112 | |
| cell cycle arrest | GO:0007050 | 37 | 0.112 | |
| stem cell differentiation | GO:0048863 | 268 | 0.112 | |
| regulation of embryonic development | GO:0045995 | 71 | 0.111 | |
| lymphocyte anergy | GO:0002249 | 4 | 0.108 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.108 | Fly |
| appendage morphogenesis | GO:0035107 | 149 | 0.108 | |
| single organism nuclear import | GO:1902593 | 95 | 0.108 | |
| endocrine system development | GO:0035270 | 98 | 0.108 | |
| endocardial cushion development | GO:0003197 | 26 | 0.108 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.107 | |
| regulation of ion transport | GO:0043269 | 215 | 0.107 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.106 | |
| necroptotic process | GO:0070266 | 21 | 0.106 | |
| positive regulation of antimicrobial peptide biosynthetic process | GO:0002807 | 1 | 0.106 | Fly |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.106 | |
| cardiac chamber morphogenesis | GO:0003206 | 93 | 0.106 | |
| regulation of epidermis development | GO:0045682 | 33 | 0.106 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.105 | |
| positive regulation of t cell cytokine production | GO:0002726 | 5 | 0.105 | Human |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.105 | |
| mesoderm development | GO:0007498 | 100 | 0.104 | |
| organ growth | GO:0035265 | 117 | 0.104 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.104 | |
| somitogenesis | GO:0001756 | 69 | 0.104 | |
| regulation of antibacterial peptide production | GO:0002786 | 1 | 0.103 | Fly |
| osteoclast differentiation | GO:0030316 | 62 | 0.103 | |
| response to nitric oxide | GO:0071731 | 4 | 0.102 | |
| negative regulation of osteoblast differentiation | GO:0045668 | 30 | 0.101 | |
| positive regulation of cell morphogenesis involved in differentiation | GO:0010770 | 72 | 0.101 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.101 | |
| negative regulation of interleukin 13 production | GO:0032696 | 2 | 0.100 | |
| nephron tubule development | GO:0072080 | 84 | 0.099 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.099 | |
| cardiac muscle tissue growth | GO:0055017 | 37 | 0.098 | |
| blood circulation | GO:0008015 | 195 | 0.097 | |
| metanephric mesenchyme morphogenesis | GO:0072133 | 4 | 0.095 | |
| mesonephric epithelium development | GO:0072163 | 94 | 0.095 | |
| negative regulation of bmp signaling pathway | GO:0030514 | 35 | 0.093 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 91 | 0.093 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.092 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.092 | |
| positive regulation of meiotic cell cycle | GO:0051446 | 15 | 0.092 | |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.091 | |
| embryonic axis specification | GO:0000578 | 30 | 0.091 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.091 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.090 | |
| cardiac septum development | GO:0003279 | 59 | 0.090 | |
| multicellular organism growth | GO:0035264 | 161 | 0.090 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.090 | Human |
| interleukin 10 secretion | GO:0072608 | 4 | 0.090 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 25 | 0.089 | |
| cardiac muscle contraction | GO:0060048 | 32 | 0.089 | |
| regulation of cell proliferation involved in heart valve morphogenesis | GO:0003250 | 1 | 0.089 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.089 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.089 | Fly |
| regulation of cd8 positive alpha beta cytotoxic t cell extravasation | GO:2000452 | 2 | 0.088 | |
| protein acylation | GO:0043543 | 64 | 0.088 | Human |
| regulation of histone modification | GO:0031056 | 56 | 0.088 | |
| positive regulation of protein oligomerization | GO:0032461 | 4 | 0.087 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.087 | |
| nephron development | GO:0072006 | 109 | 0.086 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 43 | 0.086 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.085 | |
| positive regulation of growth | GO:0045927 | 104 | 0.085 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.085 | |
| microtubule based process | GO:0007017 | 236 | 0.084 | |
| cardiac muscle cell proliferation | GO:0060038 | 31 | 0.084 | |
| chondrocyte differentiation | GO:0002062 | 72 | 0.084 | |
| interleukin 2 production | GO:0032623 | 33 | 0.084 | Human |
