Mus musculus

67 known processes

Herc1

hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1

(Aliases: MGC7618,2810449H11Rik,B230218H07,D130015N03Rik,tbl)

Herc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone methylationGO:0016571710.157
protein modification by small protein conjugation or removalGO:00706472070.099
negative regulation of intracellular signal transductionGO:19025321670.091
protein alkylationGO:0008213810.086
purine nucleotide metabolic processGO:00061633020.076
histone modificationGO:00165701590.076
methylationGO:00322591340.074
negative regulation of phosphorus metabolic processGO:00105631840.072
nucleotide metabolic processGO:00091173320.072
regulation of organelle organizationGO:00330432890.072
ribonucleotide metabolic processGO:00092592910.071
purine ribonucleoside triphosphate metabolic processGO:00092052200.070
protein ubiquitinationGO:00165671710.069
protein methylationGO:0006479810.068
small gtpase mediated signal transductionGO:0007264970.064
macromolecule methylationGO:00434141200.064
rhythmic processGO:00485111740.063
purine nucleoside metabolic processGO:00422782410.062
purine containing compound catabolic processGO:00725232130.060
glycosyl compound catabolic processGO:19016582060.059
purine ribonucleoside metabolic processGO:00461282410.057
purine containing compound metabolic processGO:00725213110.057
histone lysine methylationGO:0034968500.056
purine ribonucleoside catabolic processGO:00461302050.055
ribonucleoside triphosphate metabolic processGO:00091992200.055
regulation of cellular amino acid metabolic processGO:000652150.054
chromatin modificationGO:00165681870.054
regulation of cellular catabolic processGO:00313292420.053
organonitrogen compound catabolic processGO:19015652640.053
cation transportGO:00068123990.052
covalent chromatin modificationGO:00165691630.051
purine ribonucleotide catabolic processGO:00091542080.050
nucleoside phosphate metabolic processGO:00067533380.050
nucleoside metabolic processGO:00091162460.047
nucleoside phosphate catabolic processGO:19012922220.047
regulation of mapk cascadeGO:00434082480.046
negative regulation of cellular protein metabolic processGO:00322692470.045
purine nucleoside catabolic processGO:00061522050.044
ribonucleoside metabolic processGO:00091192450.044
amine metabolic processGO:0009308450.044
cellular amino acid metabolic processGO:00065201030.044
negative regulation of phosphate metabolic processGO:00459361840.043
nucleoside triphosphate metabolic processGO:00091412300.042
nucleobase containing small molecule metabolic processGO:00550863520.042
myeloid cell differentiationGO:00300992330.042
response to organonitrogen compoundGO:00102432460.041
peptidyl amino acid modificationGO:00181933360.041
gtp metabolic processGO:00460391440.040
purine ribonucleotide metabolic processGO:00091502900.040
aromatic compound catabolic processGO:00194392860.040
regulation of nucleotide metabolic processGO:00061401690.040
ribonucleoside catabolic processGO:00424542060.039
cellular amine metabolic processGO:0044106440.039
regulation of chromosome organizationGO:0033044830.039
striated muscle tissue developmentGO:00147062930.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
regulation of gtp catabolic processGO:00331241130.037
protein modification by small protein conjugationGO:00324461870.037
purine nucleoside triphosphate metabolic processGO:00091442260.037
gtp catabolic processGO:00061841430.037
muscle tissue developmentGO:00605373080.036
purine nucleotide catabolic processGO:00061952110.036
glycosyl compound metabolic processGO:19016572460.035
synaptic transmissionGO:00072683290.034
cellular nitrogen compound catabolic processGO:00442702800.034
synapse organizationGO:00508081250.034
nucleoside triphosphate catabolic processGO:00091432050.034
purine ribonucleoside triphosphate catabolic processGO:00092071990.034
forebrain developmentGO:00309003020.034
ribonucleoside triphosphate catabolic processGO:00092031990.034
positive regulation of protein modification processGO:00314012990.033
positive regulation of cellular amine metabolic processGO:003324050.033
regulation of cellular amine metabolic processGO:0033238200.033
apoptotic signaling pathwayGO:00971903060.032
posttranscriptional regulation of gene expressionGO:00106081550.032
ribonucleotide catabolic processGO:00092612080.032
mapk cascadeGO:00001652810.032
endomembrane system organizationGO:00102561470.032
microtubule based processGO:00070172360.032
regulation of purine nucleotide metabolic processGO:19005421690.032
cytoplasmic transportGO:00164822340.032
cellular response to organonitrogen compoundGO:00714171450.032
guanosine containing compound catabolic processGO:19010691440.031
carbohydrate derivative catabolic processGO:19011362310.031
heterocycle catabolic processGO:00467002800.031
negative regulation of protein metabolic processGO:00512482820.031
organic cyclic compound catabolic processGO:19013612950.031
negative regulation of cellular component organizationGO:00511291940.031
protein localization to membraneGO:00726571080.031
organophosphate catabolic processGO:00464342320.031
cellular ketone metabolic processGO:0042180840.030
leukocyte differentiationGO:00025213420.030
chromatin organizationGO:00063252060.030
carbohydrate metabolic processGO:00059752300.029
dna metabolic processGO:00062593030.029
regulation of synaptic growth at neuromuscular junctionGO:000858240.028
regulation of hydrolase activityGO:00513362460.028
regulation of ion transmembrane transportGO:00347651190.028
regulation of reactive oxygen species metabolic processGO:2000377400.027
intracellular protein transportGO:00068862040.027
regulation of nucleotide catabolic processGO:00308111220.027
regulation of nucleoside metabolic processGO:00091181300.027
male gamete generationGO:00482322850.027
cell adhesionGO:00071553290.026
wnt signaling pathwayGO:00160551880.026
regionalizationGO:00030023370.026
regulation of ras protein signal transductionGO:00465781140.026
peptidyl serine modificationGO:0018209830.026
cellular response to hormone stimulusGO:00328701500.026
actin filament based movementGO:0030048230.026
organelle localizationGO:00516401790.026
positive regulation of cell developmentGO:00107202370.025
response to acid chemicalGO:00011011110.025
purine nucleoside triphosphate catabolic processGO:00091462030.025
spermatogenesisGO:00072832840.025
response to peptideGO:19016521360.025
germ cell developmentGO:00072811850.025
compound eye developmentGO:004874910.025
guanosine containing compound metabolic processGO:19010681440.025
regulation of membrane potentialGO:00423911920.025
muscle cell differentiationGO:00426922610.025
regulation of purine nucleotide catabolic processGO:00331211220.025
regulation of kinase activityGO:00435492490.024
ras protein signal transductionGO:0007265770.024
synapsisGO:0007129340.024
regulation of cellular component biogenesisGO:00440871810.024
transmembrane transportGO:00550854120.024
regulation of cellular ketone metabolic processGO:0010565660.024
ribose phosphate metabolic processGO:00196932910.024
mrna metabolic processGO:0016071840.024
regulation of histone methylationGO:0031060300.024
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
cellular homeostasisGO:00197252400.023
positive regulation of nervous system developmentGO:00519622210.023
regulation of protein kinase activityGO:00458592320.023
nucleotide catabolic processGO:00091662170.023
nitrogen compound transportGO:00717052710.022
peptidyl lysine methylationGO:0018022290.022
inorganic ion transmembrane transportGO:00986602340.022
reactive oxygen species metabolic processGO:0072593840.022
rho protein signal transductionGO:0007266320.022
positive regulation of gtpase activityGO:0043547850.022
ion transmembrane transportGO:00342203610.022
cellular chemical homeostasisGO:00550822150.022
nucleoside catabolic processGO:00091642060.021
divalent inorganic cation transportGO:00725111780.021
oxidation reduction processGO:00551143420.021
cell type specific apoptotic processGO:00972852680.021
inorganic cation transmembrane transportGO:00986622070.020
dna repairGO:00062811070.020
positive regulation of protein phosphorylationGO:00019342420.020
negative regulation of phosphorylationGO:00423261660.020
circadian rhythmGO:00076231140.020
anion transportGO:00068201770.020
regulation of protein localizationGO:00328802310.019
microtubule cytoskeleton organizationGO:00002261570.019
cognitionGO:00508901490.019
skeletal system developmentGO:00015013560.019
digestive system developmentGO:00551232000.019
embryonic organ morphogenesisGO:00485622760.019
organelle fissionGO:00482851700.019
regulation of ion transportGO:00432692150.019
immune effector processGO:00022523210.019
response to oxidative stressGO:00069791230.019
regulation of neuron differentiationGO:00456642810.019
positive regulation of ras gtpase activityGO:0032320650.019
response to extracellular stimulusGO:00099911270.019
microtubule polymerization or depolymerizationGO:0031109260.019
multicellular organismal signalingGO:0035637910.019
positive regulation of organelle organizationGO:00106381280.018
organophosphate biosynthetic processGO:00904071220.018
regulation of wnt signaling pathwayGO:00301111230.018
regulation of transferase activityGO:00513382630.018
glucose homeostasisGO:00425931280.018
nuclear divisionGO:00002801580.018
microtubule nucleationGO:000702020.018
cellular protein complex assemblyGO:00436231160.018
response to insulinGO:00328681000.018
fat cell differentiationGO:00454441600.018
protein localization to plasma membraneGO:0072659570.018
regulation of cell motilityGO:20001452360.018
cellular response to insulin stimulusGO:0032869780.018
positive regulation of gtp catabolic processGO:0033126850.018
morphogenesis of embryonic epitheliumGO:00163311590.018
heart morphogenesisGO:00030071780.018
maintenance of locationGO:0051235890.018
calcium ion transportGO:00068161590.018
olfactory learningGO:000835520.017
negative regulation of mapk cascadeGO:0043409650.017
lipid localizationGO:00108761260.017
negative regulation of cell proliferationGO:00082852960.017
gene silencingGO:0016458380.017
learning or memoryGO:00076111480.017
regulation of cell projection organizationGO:00313442060.017
regulation of cell sizeGO:0008361720.017
cellular response to dna damage stimulusGO:00069742070.017
camera type eye developmentGO:00430102660.017
regulation of chromatin organizationGO:1902275570.017
cellular lipid metabolic processGO:00442553230.017
regulation of cell migrationGO:00303342190.017
divalent metal ion transportGO:00708381720.017
digestive tract developmentGO:00485651900.016
regulation of histone modificationGO:0031056560.016
negative regulation of molecular functionGO:00440922580.016
positive regulation of cell deathGO:00109422240.016
response to nutrient levelsGO:00316671090.016
neuromuscular processGO:0050905990.016
positive regulation of histone modificationGO:0031058280.016
membrane organizationGO:00610242450.016
dna recombinationGO:0006310920.016
leukocyte mediated immunityGO:00024431740.016
cellular response to peptideGO:1901653920.016
inflammatory responseGO:00069542440.016
protein targeting to membraneGO:0006612200.016
glycerolipid metabolic processGO:00464861220.016
protein maturationGO:00516041760.016
regulation of system processGO:00440572000.016
positive regulation of nucleoside metabolic processGO:0045979910.016
macromolecule catabolic processGO:00090572810.016
autophagyGO:0006914450.016
cellular calcium ion homeostasisGO:00068741190.016
histone h3 k4 methylationGO:0051568230.016
organelle assemblyGO:00709251770.016
cation transmembrane transportGO:00986552660.015
homeostasis of number of cellsGO:00488722100.015
axonogenesisGO:00074092740.015
monocarboxylic acid metabolic processGO:00327871910.015
regulation of transmembrane transportGO:00347621280.015
protein catabolic processGO:00301632210.015
phospholipid metabolic processGO:0006644870.015
regulation of cell cycleGO:00517262810.015
neuronal action potentialGO:0019228540.015
cellular response to lipidGO:00713961450.015
negative regulation of protein modification processGO:00314001630.015
regulation of homeostatic processGO:00328441820.015
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.015
peptidyl lysine modificationGO:0018205770.015
stress activated mapk cascadeGO:0051403800.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
locomotory behaviorGO:00076261950.015
response to oxygen levelsGO:0070482620.015
regulation of defense responseGO:00313472330.015
action potentialGO:0001508780.015
regulation of cell cycle processGO:00105641600.015
positive regulation of growthGO:00459271040.015
response to inorganic substanceGO:0010035960.015
negative regulation of synapse assemblyGO:005196430.015
sequestering of calcium ionGO:0051208180.015
regulation of chromatin modificationGO:1903308570.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
regulation of intracellular transportGO:00323861590.014
protein targetingGO:00066051430.014
sequestering of metal ionGO:0051238190.014
multicellular organism growthGO:00352641610.014
positive regulation of cellular catabolic processGO:00313311480.014
regulation of cytoskeleton organizationGO:00514931220.014
positive regulation of chromatin modificationGO:1903310280.014
skeletal muscle organ developmentGO:00605381630.014
neural tube closureGO:0001843900.014
rac protein signal transductionGO:0016601130.014
regulation of secretionGO:00510462740.014
calcium ion transmembrane transportGO:0070588850.014
multi multicellular organism processGO:00447061090.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
carbohydrate homeostasisGO:00335001280.014
nucleoside monophosphate metabolic processGO:0009123850.014
response to peptide hormoneGO:00434341270.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
positive regulation of nucleotide catabolic processGO:0030813880.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
regulation of rho protein signal transductionGO:0035023710.014
regulation of microtubule polymerization or depolymerizationGO:0031110200.014
regulation of cellular component sizeGO:00325351210.014
cellular response to growth factor stimulusGO:00713631970.014
anatomical structure homeostasisGO:00602491450.014
regulation of anatomical structure sizeGO:00900661780.013
negative regulation of cell developmentGO:00107211690.013
protein processingGO:00164851630.013
positive regulation of nucleotide metabolic processGO:00459811140.013
carbohydrate derivative biosynthetic processGO:19011371830.013
histone h4 k16 acetylationGO:004398430.013
protein localization to organelleGO:00333651850.013
engulfment of apoptotic cellGO:004365230.013
regulation of myeloid cell differentiationGO:0045637960.013
neural precursor cell proliferationGO:00613511210.013
cytokine productionGO:00018163190.013
cellular response to peptide hormone stimulusGO:0071375920.013
plasma membrane organizationGO:0007009900.013
regulation of protein processingGO:0070613960.013
response to growth factorGO:00708481980.013
male meiosisGO:0007140370.013
regulation of cell substrate adhesionGO:0010810730.013
regulation of apoptotic signaling pathwayGO:20012331970.013
telencephalon developmentGO:00215371860.013
response to starvationGO:0042594650.013
positive regulation of chromosome organizationGO:2001252330.013
organic hydroxy compound metabolic processGO:19016152030.013
fertilizationGO:00095661270.013
ubiquitin dependent protein catabolic processGO:00065111290.013
dendrite developmentGO:00163581150.013
cytoskeleton dependent intracellular transportGO:0030705500.012
meiotic nuclear divisionGO:00071261150.012
transmission of nerve impulseGO:0019226760.012
translationGO:0006412930.012
meiosis iGO:0007127600.012
b cell activationGO:00421131610.012
cellular response to biotic stimulusGO:0071216920.012
lipid biosynthetic processGO:00086101790.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of response to woundingGO:19030341890.012
positive regulation of hydrolase activityGO:00513451480.012
cell recognitionGO:0008037830.012
dephosphorylationGO:00163111290.012
midgut developmentGO:000749440.012
regulation of protein complex assemblyGO:0043254830.012
positive regulation of neuron projection developmentGO:0010976790.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
response to lipopolysaccharideGO:00324961280.012
protein polymerizationGO:0051258570.012
jnk cascadeGO:0007254720.012
regulation of ras gtpase activityGO:0032318880.012
adult locomotory behaviorGO:0008344910.012
cation homeostasisGO:00550802120.012
regulation of cellular response to stressGO:00801351590.012
cell fate commitmentGO:00451652100.012
interleukin 6 productionGO:0032635580.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
microtubule based movementGO:0007018840.012
positive regulation of protein kinase activityGO:00458601440.012
establishment of organelle localizationGO:00516561220.012
exocytosisGO:00068871210.012
negative regulation of organelle organizationGO:0010639900.012
cell substrate adhesionGO:00315891300.012
establishment or maintenance of cell polarityGO:0007163860.012
negative regulation of cellular amine metabolic processGO:003323910.012
gastrulationGO:00073691160.012
glycerophospholipid metabolic processGO:0006650710.011
cellular response to molecule of bacterial originGO:0071219830.011
actin cytoskeleton organizationGO:00300362200.011
appendage developmentGO:00487361660.011
establishment of protein localization to organelleGO:00725941180.011
digestive tract morphogenesisGO:00485461470.011
asymmetric stem cell divisionGO:009872230.011
blood vessel morphogenesisGO:00485142850.011
regulation of neuron projection developmentGO:00109751690.011
response to molecule of bacterial originGO:00022371430.011
microtubule based transportGO:0010970500.011
muscle system processGO:00030121410.011
oocyte constructionGO:000730820.011
t cell activationGO:00421102890.011
positive regulation of kinase activityGO:00336741550.011
epithelial tube morphogenesisGO:00605623030.011
regulation of protein maturationGO:1903317960.011
body morphogenesisGO:0010171450.011
cellular carbohydrate metabolic processGO:00442621190.011
regulation of establishment of protein localizationGO:00702011810.011
protein depolymerizationGO:0051261340.011
response to decreased oxygen levelsGO:0036293590.011
response to transforming growth factor betaGO:0071559880.011
circulatory system processGO:00030131970.011
retrograde transport endosome to golgiGO:004214720.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
organonitrogen compound biosynthetic processGO:19015661920.011
male sex differentiationGO:00466611090.011
rna processingGO:00063961050.011
metal ion homeostasisGO:00550651890.011
mitotic cell cycleGO:00002781950.011
positive regulation of programmed cell deathGO:00430682180.011
i kappab kinase nf kappab signalingGO:0007249850.011
tube formationGO:00351481400.011
cell activation involved in immune responseGO:00022631260.011
amide transportGO:00428861380.011
cellular metal ion homeostasisGO:00068751510.011
kidney developmentGO:00018222130.011
skeletal system morphogenesisGO:00487052030.011
peptide hormone secretionGO:00300721090.011
regulation of protein serine threonine kinase activityGO:00719001570.011
rna interferenceGO:001624620.011
cellular component assembly involved in morphogenesisGO:00109271390.011
primary neural tube formationGO:0014020950.011
cardiac muscle cell differentiationGO:0055007690.011
chemotaxisGO:00069352470.011
divalent inorganic cation homeostasisGO:00725071380.010
peptide transportGO:00158331330.010
regulation of lymphocyte activationGO:00512492400.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
cellular response to decreased oxygen levelsGO:0036294180.010
positive regulation of histone methylationGO:0031062160.010
regulation of microtubule based processGO:0032886520.010
neural tube formationGO:00018411080.010
immune response regulating signaling pathwayGO:00027641250.010
male genitalia morphogenesisGO:004880840.010
positive regulation of dna templated transcription elongationGO:003278620.010
second messenger mediated signalingGO:0019932730.010
purine ribonucleoside monophosphate catabolic processGO:0009169570.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
glucose metabolic processGO:0006006920.010
adult behaviorGO:00305341350.010
sensory perception of soundGO:0007605970.010
mitochondrion distributionGO:004831140.010
peptide secretionGO:00027901140.010
cardiac muscle tissue developmentGO:00487381300.010

Herc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.048
neuropathyDOID:87000.015
musculoskeletal system diseaseDOID:1700.012
immune system diseaseDOID:291400.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
central nervous system diseaseDOID:33100.011