Mus musculus

14 known processes

Herc4

hect domain and RLD 4

(Aliases: mKIAA1593,4921531D01Rik,9530080M15Rik,1700056O17Rik)

Herc4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatogenesisGO:00072832840.100
regulation of cell activationGO:00508652890.096
protein modification by small protein conjugationGO:00324461870.081
Mouse
male gamete generationGO:00482322850.078
cellular protein catabolic processGO:00442571550.067
Mouse
mapk cascadeGO:00001652810.067
regulation of cytokine productionGO:00018172660.064
regulation of t cell activationGO:00508631700.062
regulation of cellular amino acid metabolic processGO:000652150.058
ribonucleotide catabolic processGO:00092612080.058
regulation of lymphocyte activationGO:00512492400.057
protein ubiquitinationGO:00165671710.057
Mouse
negative regulation of cellular amine metabolic processGO:003323910.053
cellular ketone metabolic processGO:0042180840.053
dna metabolic processGO:00062593030.051
cellular amino acid metabolic processGO:00065201030.051
small gtpase mediated signal transductionGO:0007264970.050
regulation of cellular amine metabolic processGO:0033238200.048
ubiquitin dependent protein catabolic processGO:00065111290.046
Mouse
negative regulation of synapse assemblyGO:005196430.046
regulation of cellular ketone metabolic processGO:0010565660.046
positive regulation of mapk cascadeGO:00434101700.045
spermatid developmentGO:00072861080.045
posttranscriptional regulation of gene expressionGO:00106081550.044
t cell proliferationGO:00420981200.043
cytokine productionGO:00018163190.041
negative regulation of t cell activationGO:0050868650.040
negative regulation of cellular protein metabolic processGO:00322692470.039
protein modification by small protein conjugation or removalGO:00706472070.039
Mouse
purine containing compound metabolic processGO:00725213110.039
modification dependent protein catabolic processGO:00199411330.038
Mouse
t cell activationGO:00421102890.038
spermatid differentiationGO:00485151150.038
negative regulation of protein metabolic processGO:00512482820.037
lymphocyte proliferationGO:00466511640.037
aromatic compound catabolic processGO:00194392860.037
protein catabolic processGO:00301632210.036
Mouse
negative regulation of cell activationGO:00508661110.036
cation transportGO:00068123990.036
positive regulation of cytokine productionGO:00018191740.036
peptidyl amino acid modificationGO:00181933360.036
regulation of organelle organizationGO:00330432890.035
proteolysis involved in cellular protein catabolic processGO:00516031470.034
Mouse
amine metabolic processGO:0009308450.034
negative regulation of immune system processGO:00026832090.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.032
cellular nitrogen compound catabolic processGO:00442702800.031
purine containing compound catabolic processGO:00725232130.031
negative regulation of molecular functionGO:00440922580.031
immune response activating signal transductionGO:00027571160.031
negative regulation of cell proliferationGO:00082852960.030
positive regulation of protein modification processGO:00314012990.029
immune response regulating signaling pathwayGO:00027641250.029
carbohydrate derivative catabolic processGO:19011362310.029
respiratory tube developmentGO:00303231670.029
regulation of proteolysisGO:00301621640.029
nucleoside catabolic processGO:00091642060.028
nitrogen compound transportGO:00717052710.028
nucleobase containing small molecule metabolic processGO:00550863520.028
fat cell differentiationGO:00454441600.028
cellular response to dna damage stimulusGO:00069742070.028
regulation of response to woundingGO:19030341890.027
transmembrane transportGO:00550854120.027
response to lipopolysaccharideGO:00324961280.027
regulation of cytoskeleton organizationGO:00514931220.026
regulation of mapk cascadeGO:00434082480.026
ribonucleoside triphosphate catabolic processGO:00092031990.026
positive regulation of protein phosphorylationGO:00019342420.025
regulation of defense responseGO:00313472330.025
nucleoside phosphate metabolic processGO:00067533380.025
purine ribonucleotide catabolic processGO:00091542080.025
heterocycle catabolic processGO:00467002800.025
regulation of map kinase activityGO:00434051200.025
activation of immune responseGO:00022531380.025
positive regulation of cell developmentGO:00107202370.024
innate immune responseGO:00450871570.024
purine nucleotide catabolic processGO:00061952110.023
cytoplasmic transportGO:00164822340.023
negative regulation of cellular component organizationGO:00511291940.023
lung developmentGO:00303241640.023
negative regulation of lymphocyte activationGO:0051250910.023
ribose phosphate metabolic processGO:00196932910.023
purine nucleotide metabolic processGO:00061633020.023
limb developmentGO:00601731660.023
negative regulation of growthGO:0045926990.022
ribonucleoside metabolic processGO:00091192450.022
interspecies interaction between organismsGO:0044419830.022
nucleoside phosphate catabolic processGO:19012922220.022
regulation of hydrolase activityGO:00513362460.022
dna repairGO:00062811070.022
cellular macromolecule catabolic processGO:00442652060.022
Mouse
organelle localizationGO:00516401790.022
regulation of apoptotic signaling pathwayGO:20012331970.021
regulation of inflammatory responseGO:00507271470.021
leukocyte proliferationGO:00706611720.021
purine ribonucleotide metabolic processGO:00091502900.021
ras protein signal transductionGO:0007265770.021
nucleoside triphosphate catabolic processGO:00091432050.021
nucleoside metabolic processGO:00091162460.021
modification dependent macromolecule catabolic processGO:00436321330.021
Mouse
substrate adhesion dependent cell spreadingGO:0034446300.021
organic cyclic compound catabolic processGO:19013612950.021
regulation of transferase activityGO:00513382630.021
regulation of cell cycle processGO:00105641600.021
regulation of cellular catabolic processGO:00313292420.021
apoptotic signaling pathwayGO:00971903060.021
negative regulation of intracellular signal transductionGO:19025321670.021
cell type specific apoptotic processGO:00972852680.021
cellular protein complex assemblyGO:00436231160.020
regulation of t cell proliferationGO:0042129920.020
hematopoietic progenitor cell differentiationGO:00022441430.020
cellular response to lipidGO:00713961450.020
negative regulation of cellular amino acid metabolic processGO:004576300.020
macromolecule catabolic processGO:00090572810.020
Mouse
regulation of cell cycleGO:00517262810.020
cellular amine metabolic processGO:0044106440.020
regulation of ras protein signal transductionGO:00465781140.020
skeletal muscle organ developmentGO:00605381630.020
digestive system developmentGO:00551232000.020
compound eye developmentGO:004874910.020
protein localization to organelleGO:00333651850.019
nucleotide metabolic processGO:00091173320.019
positive regulation of nervous system developmentGO:00519622210.019
regulation of nucleotide metabolic processGO:00061401690.019
cellular response to molecule of bacterial originGO:0071219830.019
rho protein signal transductionGO:0007266320.019
positive regulation of map kinase activityGO:0043406840.019
histone modificationGO:00165701590.018
response to organonitrogen compoundGO:00102432460.018
nucleotide catabolic processGO:00091662170.018
negative regulation of phosphate metabolic processGO:00459361840.018
regulation of lymphocyte proliferationGO:00506701170.018
regulation of purine nucleotide catabolic processGO:00331211220.018
multi multicellular organism processGO:00447061090.018
positive regulation of hydrolase activityGO:00513451480.018
germ cell developmentGO:00072811850.018
negative regulation of phosphorylationGO:00423261660.017
positive regulation of transferase activityGO:00513471670.017
positive regulation of organelle organizationGO:00106381280.017
homeostasis of number of cellsGO:00488722100.017
nucleoside triphosphate metabolic processGO:00091412300.017
lateral inhibitionGO:004633110.017
regulation of protein kinase activityGO:00458592320.017
sensory perceptionGO:00076002450.017
purine ribonucleoside triphosphate catabolic processGO:00092071990.017
negative regulation of mesenchymal cell proliferationGO:007220130.016
regulation of cellular response to stressGO:00801351590.016
cell substrate adhesionGO:00315891300.016
positive regulation of protein serine threonine kinase activityGO:00719021060.016
multicellular organism growthGO:00352641610.016
positive regulation of lymphocyte activationGO:00512511400.016
positive regulation of programmed cell deathGO:00430682180.016
positive regulation of defense responseGO:00313491240.016
response to molecule of bacterial originGO:00022371430.016
organophosphate catabolic processGO:00464342320.016
chemotaxisGO:00069352470.016
purine ribonucleoside metabolic processGO:00461282410.016
protein maturationGO:00516041760.016
regulation of nucleotide catabolic processGO:00308111220.016
neuron deathGO:00709971540.016
positive regulation of kinase activityGO:00336741550.016
cell fate commitmentGO:00451652100.016
regulation of cell morphogenesis involved in differentiationGO:00107691510.016
gland developmentGO:00487323300.015
Mouse
cellular response to organonitrogen compoundGO:00714171450.015
peptidyl tyrosine modificationGO:00182121450.015
regulation of cellular component sizeGO:00325351210.015
cellular homeostasisGO:00197252400.015
appendage developmentGO:00487361660.015
protein processingGO:00164851630.015
leukocyte mediated immunityGO:00024431740.015
dna recombinationGO:0006310920.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
regulation of anatomical structure sizeGO:00900661780.015
negative regulation of neuron apoptotic processGO:0043524920.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
i kappab kinase nf kappab signalingGO:0007249850.015
glycosyl compound metabolic processGO:19016572460.015
response to peptideGO:19016521360.015
response to acid chemicalGO:00011011110.015
regulation of protein catabolic processGO:00421761080.015
carbohydrate metabolic processGO:00059752300.015
myeloid cell homeostasisGO:00022621140.015
regulation of protein localizationGO:00328802310.015
regulation of homeostatic processGO:00328441820.015
sensory organ morphogenesisGO:00905962420.015
purine nucleoside metabolic processGO:00422782410.015
purine ribonucleoside catabolic processGO:00461302050.015
dephosphorylationGO:00163111290.014
regulation of nucleoside metabolic processGO:00091181300.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
meiosis iGO:0007127600.014
immune effector processGO:00022523210.014
ribonucleoside catabolic processGO:00424542060.014
anatomical structure homeostasisGO:00602491450.014
positive regulation of cell activationGO:00508671580.014
regulation of leukocyte proliferationGO:00706631210.014
negative regulation of t cell proliferationGO:0042130380.014
endocytosisGO:00068971680.014
Mouse
cellular response to hormone stimulusGO:00328701500.014
regulation of protein processingGO:0070613960.014
wnt signaling pathwayGO:00160551880.014
hepaticobiliary system developmentGO:0061008670.014
peptidyl serine modificationGO:0018209830.014
negative regulation of nervous system developmentGO:00519611560.014
positive regulation of cellular catabolic processGO:00313311480.014
regulation of cell projection organizationGO:00313442060.014
fertilizationGO:00095661270.014
Mouse
regulation of cell migrationGO:00303342190.014
multi organism behaviorGO:0051705620.014
rna processingGO:00063961050.014
inflammatory responseGO:00069542440.014
cation transmembrane transportGO:00986552660.014
erk1 and erk2 cascadeGO:0070371770.014
nuclear divisionGO:00002801580.014
cellular chemical homeostasisGO:00550822150.014
regulation of kinase activityGO:00435492490.014
meiotic cell cycle processGO:1903046770.013
antigen receptor mediated signaling pathwayGO:0050851640.013
regulation of innate immune responseGO:0045088910.013
terminal button organizationGO:007255330.013
maintenance of locationGO:0051235890.013
Worm
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.013
b cell differentiationGO:0030183780.013
carbohydrate derivative biosynthetic processGO:19011371830.013
mitochondrion organizationGO:00070051340.013
cellular response to lipopolysaccharideGO:0071222770.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
actin cytoskeleton organizationGO:00300362200.013
regulation of cellular component biogenesisGO:00440871810.013
inorganic cation transmembrane transportGO:00986622070.013
establishment of organelle localizationGO:00516561220.013
positive regulation of nucleotide metabolic processGO:00459811140.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
embryonic epithelial tube formationGO:00018381300.013
immune response regulating cell surface receptor signaling pathwayGO:0002768800.013
response to oxidative stressGO:00069791230.013
positive regulation of protein kinase activityGO:00458601440.013
regulation of translationGO:0006417710.013
organelle fissionGO:00482851700.013
ion transmembrane transportGO:00342203610.013
cellular response to peptideGO:1901653920.012
lymphocyte differentiationGO:00300982420.012
translationGO:0006412930.012
regulation of neural precursor cell proliferationGO:2000177700.012
lipid localizationGO:00108761260.012
Worm
response to organic cyclic compoundGO:00140701980.012
divalent inorganic cation transportGO:00725111780.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
respiratory system developmentGO:00605411900.012
covalent chromatin modificationGO:00165691630.012
pharynx developmentGO:006046510.012
regulation of ion transportGO:00432692150.012
regulation of ossificationGO:00302781120.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
regulation of multi organism processGO:00439001110.012
cellular response to biotic stimulusGO:0071216920.012
ribonucleotide metabolic processGO:00092592910.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
neuron apoptotic processGO:00514021420.012
transmission of nerve impulseGO:0019226760.012
positive regulation of gtpase activityGO:0043547850.012
canonical wnt signaling pathwayGO:00600701300.012
regulation of neuron projection developmentGO:00109751690.012
chromosome organization involved in meiosisGO:0070192390.012
negative regulation of lymphocyte proliferationGO:0050672450.012
response to growth factorGO:00708481980.012
multicellular organismal signalingGO:0035637910.011
positive regulation of apoptotic processGO:00430652170.011
actin polymerization or depolymerizationGO:0008154540.011
response to light stimulusGO:00094161350.011
regulation of body fluid levelsGO:00508781620.011
positive regulation of cellular amine metabolic processGO:003324050.011
b cell activationGO:00421131610.011
positive regulation of gtp catabolic processGO:0033126850.011
protein acylationGO:0043543640.011
multicellular organismal homeostasisGO:00488711640.011
skin developmentGO:00435882200.011
regulation of gtp catabolic processGO:00331241130.011
cellular ion homeostasisGO:00068731650.011
purine nucleoside catabolic processGO:00061522050.011
regulation of establishment of protein localizationGO:00702011810.011
tissue homeostasisGO:00018941150.011
regulation of neuron apoptotic processGO:00435231220.011
digestive tract morphogenesisGO:00485461470.011
metal ion homeostasisGO:00550651890.011
glucose homeostasisGO:00425931280.011
anion transportGO:00068201770.011
response to peptide hormoneGO:00434341270.011
response to topologically incorrect proteinGO:0035966250.011
regulation of neuron differentiationGO:00456642810.011
positive regulation of cell deathGO:00109422240.011
cellular response to cytokine stimulusGO:00713451890.011
double strand break repairGO:0006302480.011
response to insulinGO:00328681000.011
ossificationGO:00015032160.011
synaptic transmissionGO:00072683290.011
regulation of b cell activationGO:0050864810.011
chromatin modificationGO:00165681870.011
oocyte axis specificationGO:000730920.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
labyrinthine layer developmentGO:0060711490.011
development of primary sexual characteristicsGO:00451371430.010
Mouse
regulation of wnt signaling pathwayGO:00301111230.010
tissue remodelingGO:00487711020.010
lymphocyte mediated immunityGO:00024491390.010
regulation of endocytosisGO:0030100690.010
glycerolipid metabolic processGO:00464861220.010
muscle tissue developmentGO:00605373080.010
cell divisionGO:00513011200.010
divalent metal ion transportGO:00708381720.010
camera type eye developmentGO:00430102660.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.010
negative regulation of phosphorus metabolic processGO:00105631840.010
appendage morphogenesisGO:00351071490.010
negative regulation of transferase activityGO:0051348850.010
regulation of neuron deathGO:19012141340.010

Herc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
cancerDOID:16200.015
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015
disease of metabolismDOID:001466700.012