Mus musculus

107 known processes

Dhx58

DEXH (Asp-Glu-X-His) box polypeptide 58

(Aliases: D11Lgp2e,B430001I08Rik,Lgp2,LPG2)

Dhx58 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of viral genome replicationGO:0045071100.995
viral processGO:0016032410.985
Mouse
interspecies interaction between organismsGO:0044419830.961
Mouse
viral genome replicationGO:0019079170.873
Mouse
toll like receptor 7 signaling pathwayGO:003415440.769
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.734
Mouse
negative regulation of multi organism processGO:0043901680.687
regulation of innate immune responseGO:0045088910.638
regulation of viral genome replicationGO:0045069130.623
Mouse
positive regulation of defense responseGO:00313491240.587
immune response regulating signaling pathwayGO:00027641250.552
defense response to other organismGO:00985421970.510
activation of innate immune responseGO:0002218560.492
positive regulation of innate immune responseGO:0045089800.476
symbiosis encompassing mutualism through parasitismGO:0044403830.474
Mouse
negative regulation of viral processGO:0048525230.390
defense response to virusGO:0051607680.374
toll like receptor 9 signaling pathwayGO:003416260.352
pattern recognition receptor signaling pathwayGO:0002221470.347
response to type i interferonGO:0034340120.329
innate immune responseGO:00450871570.286
regulation of interferon beta productionGO:0032648130.285
Mouse
positive regulation of type i interferon mediated signaling pathwayGO:006034040.275
regulation of type i interferon mediated signaling pathwayGO:006033870.258
viral life cycleGO:0019058360.250
Mouse
regulation of multi organism processGO:00439001110.230
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.212
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.212
negative regulation of immune effector processGO:0002698550.206
myeloid cell differentiationGO:00300992330.193
positive regulation of interferon alpha productionGO:003272740.180
immune effector processGO:00022523210.178
carbohydrate metabolic processGO:00059752300.172
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.162
rig i signaling pathwayGO:003952940.150
positive regulation of type i interferon productionGO:0032481140.139
type i interferon signaling pathwayGO:0060337100.132
regulation of sequence specific dna binding transcription factor activityGO:00510901060.125
activation of immune responseGO:00022531380.123
macromolecule catabolic processGO:00090572810.117
response to dsrnaGO:0043331300.100
Mouse Worm
cellular response to organic cyclic compoundGO:0071407870.100
Mouse Worm
posttranscriptional regulation of gene expressionGO:00106081550.098
Mouse Worm
organonitrogen compound biosynthetic processGO:19015661920.098
protein modification by small protein conjugationGO:00324461870.096
rna catabolic processGO:0006401290.092
regulation of type i interferon productionGO:0032479220.091
nucleotide biosynthetic processGO:0009165780.090
organic cyclic compound catabolic processGO:19013612950.088
Worm
regulation of nlrp3 inflammasome complex assemblyGO:190022540.084
toll like receptor signaling pathwayGO:0002224380.082
cellular response to interferon alphaGO:003545740.080
cellular response to lipidGO:00713961450.079
positive regulation of response to cytokine stimulusGO:0060760110.079
regulation of cellular ketone metabolic processGO:0010565660.078
regulation of cell activationGO:00508652890.075
intracellular protein transportGO:00068862040.074
antigen processing and presentationGO:0019882470.071
cellular macromolecule catabolic processGO:00442652060.068
positive regulation of immune effector processGO:00026991070.067
regulation of response to biotic stimulusGO:0002831380.067
dna metabolic processGO:00062593030.066
cellular nitrogen compound catabolic processGO:00442702800.066
Worm
regulation of cellular amine metabolic processGO:0033238200.065
immune response activating cell surface receptor signaling pathwayGO:0002429720.062
interferon beta productionGO:0032608160.061
Mouse
immune response activating signal transductionGO:00027571160.060
response to organic cyclic compoundGO:00140701980.060
Mouse Worm
protein import into nucleusGO:0006606950.060
antigen processing and presentation of exogenous antigenGO:0019884260.059
regulation of defense response to virus by hostGO:005069180.058
purine containing compound metabolic processGO:00725213110.057
Worm
nucleoside phosphate biosynthetic processGO:1901293790.056
cytokine biosynthetic processGO:0042089680.055
chromatin organizationGO:00063252060.055
regulation of defense response to virusGO:0050688180.054
regulation of antimicrobial humoral responseGO:000275930.054
regulation of interferon beta biosynthetic processGO:004535740.053
cellular response to cytokine stimulusGO:00713451890.053
nucleoside phosphate metabolic processGO:00067533380.053
Worm
stem cell differentiationGO:00488632680.052
Mouse
regulation of defense responseGO:00313472330.051
positive regulation of viral genome replicationGO:004507020.051
viral transcriptionGO:001908330.050
cellular lipid metabolic processGO:00442553230.050
t cell activationGO:00421102890.048
positive regulation of actin nucleationGO:005112730.048
protein acylationGO:0043543640.047
neuronal action potentialGO:0019228540.047
antigen processing and presentation of exogenous peptide antigenGO:0002478210.046
protein modification by small protein conjugation or removalGO:00706472070.046
cellular protein catabolic processGO:00442571550.045
negative regulation of cytokine productionGO:0001818840.045
cellular response to dna damage stimulusGO:00069742070.045
Worm
cytoplasmic transportGO:00164822340.044
proteolysis involved in cellular protein catabolic processGO:00516031470.044
cellular amine metabolic processGO:0044106440.043
modification dependent macromolecule catabolic processGO:00436321330.043
ear developmentGO:00435832000.043
Mouse
interleukin 6 productionGO:0032635580.043
histone modificationGO:00165701590.042
modification dependent protein catabolic processGO:00199411330.042
reactive oxygen species metabolic processGO:0072593840.042
intracellular receptor signaling pathwayGO:0030522740.041
methylationGO:00322591340.039
regulation of cell cycleGO:00517262810.038
Mouse
regulation of viral transcriptionGO:004678230.038
organelle assemblyGO:00709251770.038
Mouse
erythrocyte differentiationGO:0030218880.038
negative regulation of toll like receptor signaling pathwayGO:0034122140.037
aromatic compound catabolic processGO:00194392860.037
Worm
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathwayGO:003953120.036
immune response regulating cell surface receptor signaling pathwayGO:0002768800.036
spermatogenesisGO:00072832840.036
positive regulation of viral entry into host cellGO:004659830.035
regulation of cellular amino acid metabolic processGO:000652150.035
glycosylationGO:0070085620.035
viral gene expressionGO:001908030.035
positive regulation of cytokine productionGO:00018191740.034
regulation of cellular catabolic processGO:00313292420.034
regulation of leukocyte mediated immunityGO:00027031040.034
regulation of actin nucleationGO:005112540.033
nucleobase containing small molecule metabolic processGO:00550863520.033
Worm
organophosphate biosynthetic processGO:00904071220.033
negative regulation of protein metabolic processGO:00512482820.033
peptidyl amino acid modificationGO:00181933360.033
purine ribonucleoside catabolic processGO:00461302050.032
Worm
regulation of organelle organizationGO:00330432890.032
myeloid dendritic cell differentiationGO:0043011160.032
multicellular organismal homeostasisGO:00488711640.031
negative regulation of nervous system developmentGO:00519611560.031
Mouse
regulation of response to cytokine stimulusGO:0060759230.031
cellular chemical homeostasisGO:00550822150.031
nucleocytoplasmic transportGO:00069131390.031
purine ribonucleoside triphosphate metabolic processGO:00092052200.030
Worm
regulation of membrane potentialGO:00423911920.030
cytokine mediated signaling pathwayGO:00192211150.029
antimicrobial peptide productionGO:000277520.029
peptidyl lysine methylationGO:0018022290.029
cellular response to biotic stimulusGO:0071216920.028
cellular ketone metabolic processGO:0042180840.028
negative regulation of defense response to virusGO:005068760.028
regulation of synaptic growth at neuromuscular junctionGO:000858240.028
positive regulation of protein modification processGO:00314012990.028
positive regulation of interleukin 8 productionGO:003275720.028
cellular amino acid metabolic processGO:00065201030.028
cellular response to organonitrogen compoundGO:00714171450.028
protein polyubiquitinationGO:0000209330.027
regulation of tumor necrosis factor productionGO:0032680490.027
purine nucleoside monophosphate metabolic processGO:0009126810.027
Worm
regulation of toll like receptor signaling pathwayGO:0034121200.027
cellular response to type i interferonGO:0071357100.026
cytokine metabolic processGO:0042107710.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
lipid localizationGO:00108761260.026
positive regulation of kinase activityGO:00336741550.026
heterocycle catabolic processGO:00467002800.026
Worm
regulation of protein transportGO:00512231630.025
anatomical structure homeostasisGO:00602491450.025
wound healingGO:00420601570.025
Mouse
epithelial cell proliferationGO:00506731740.025
response to radiationGO:00093141650.025
interleukin 8 productionGO:003263740.025
protein catabolic processGO:00301632210.025
ribonucleoside catabolic processGO:00424542060.024
Worm
regulation of interleukin 8 productionGO:003267730.024
protein ubiquitinationGO:00165671710.024
protein methylationGO:0006479810.024
purine nucleotide metabolic processGO:00061633020.024
Worm
positive regulation of cellular amine metabolic processGO:003324050.024
purine nucleotide biosynthetic processGO:0006164650.024
positive regulation of intracellular transportGO:0032388700.023
negative regulation of cellular protein metabolic processGO:00322692470.023
regulation of cellular component biogenesisGO:00440871810.023
sequestering of metal ionGO:0051238190.023
purine containing compound catabolic processGO:00725232130.023
Worm
glycoprotein biosynthetic processGO:0009101890.023
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.023
defense response to bacteriumGO:00427421190.023
ribonucleoside triphosphate metabolic processGO:00091992200.023
Worm
macromolecule methylationGO:00434141200.022
negative regulation of cellular component organizationGO:00511291940.022
lymphocyte proliferationGO:00466511640.022
negative regulation of immune system processGO:00026832090.022
homeostasis of number of cellsGO:00488722100.022
ubiquitin dependent protein catabolic processGO:00065111290.022
negative regulation of interferon beta productionGO:003268830.022
male gamete generationGO:00482322850.021
digestive system developmentGO:00551232000.021
Mouse
regulation of cytoplasmic transportGO:19036491120.021
regulation of proteolysisGO:00301621640.021
protein importGO:00170381010.020
protein glycosylationGO:0006486550.020
cell activation involved in immune responseGO:00022631260.020
maintenance of locationGO:0051235890.020
positive regulation of jnk cascadeGO:0046330460.020
gland developmentGO:00487323300.020
regulation of lymphocyte activationGO:00512492400.020
membrane organizationGO:00610242450.020
innate immune response activating signal transductionGO:0002758500.020
atp metabolic processGO:0046034750.020
Worm
regulation of cytokine biosynthetic processGO:0042035590.020
nucleotide metabolic processGO:00091173320.020
Worm
hematopoietic progenitor cell differentiationGO:00022441430.020
peptidyl lysine modificationGO:0018205770.020
extrinsic apoptotic signaling pathwayGO:00971911260.020
divalent metal ion transportGO:00708381720.020
myeloid cell homeostasisGO:00022621140.020
regulation of interferon gamma productionGO:0032649570.019
positive regulation of adaptive immune responseGO:0002821610.019
positive regulation of nf kappab transcription factor activityGO:0051092300.019
positive regulation of protein kinase activityGO:00458601440.019
mapk cascadeGO:00001652810.019
purine nucleoside monophosphate catabolic processGO:0009128580.019
Worm
myeloid dendritic cell activationGO:0001773250.019
positive regulation of protein localization to nucleusGO:1900182300.019
regulation of nucleocytoplasmic transportGO:0046822730.019
covalent chromatin modificationGO:00165691630.019
regulation of adaptive immune responseGO:0002819900.019
internal protein amino acid acetylationGO:0006475420.019
microtubule based processGO:00070172360.019
Mouse
regulation of interleukin 6 productionGO:0032675550.019
ribose phosphate metabolic processGO:00196932910.019
Worm
germ cell developmentGO:00072811850.019
protein targetingGO:00066051430.018
limb morphogenesisGO:00351081490.018
Mouse
monosaccharide metabolic processGO:00059961060.018
carbohydrate derivative biosynthetic processGO:19011371830.018
ion transmembrane transportGO:00342203610.018
cation homeostasisGO:00550802120.018
histone acetylationGO:0016573410.018
positive regulation of cytokine biosynthetic processGO:0042108400.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
lipoprotein metabolic processGO:0042157430.018
transmembrane transportGO:00550854120.018
myeloid leukocyte differentiationGO:00025731190.018
cd8 positive alpha beta t cell proliferationGO:003574010.018
connective tissue developmentGO:00614481790.018
Mouse
dna recombinationGO:0006310920.018
posttranscriptional gene silencingGO:0016441100.018
Mouse Worm
ribonucleoside monophosphate metabolic processGO:0009161800.018
Worm
positive regulation of organelle organizationGO:00106381280.018
chromatin modificationGO:00165681870.018
tumor necrosis factor productionGO:0032640500.018
proteasomal protein catabolic processGO:0010498980.018
leukocyte mediated immunityGO:00024431740.018
positive regulation of interferon beta productionGO:003272880.017
Mouse
action potentialGO:0001508780.017
nitrogen compound transportGO:00717052710.017
sequestering of calcium ionGO:0051208180.017
fat cell differentiationGO:00454441600.017
negative regulation of cell proliferationGO:00082852960.017
Mouse
regulation of cell migrationGO:00303342190.017
nuclear importGO:0051170950.017
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.017
mitotic cell cycleGO:00002781950.017
necrotic cell deathGO:0070265300.017
inorganic cation transmembrane transportGO:00986622070.017
nucleoside phosphate catabolic processGO:19012922220.016
Worm
apoptotic signaling pathwayGO:00971903060.016
interaction with hostGO:0051701220.016
protein localization to nucleusGO:00345041210.016
purine ribonucleotide catabolic processGO:00091542080.016
Worm
cation transportGO:00068123990.016
protein localization to organelleGO:00333651850.016
cellular component assembly involved in morphogenesisGO:00109271390.016
Mouse
adaptive immune responseGO:00022501550.016
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.016
macromolecule glycosylationGO:0043413550.016
regulation of neuron differentiationGO:00456642810.016
Mouse
cytokine productionGO:00018163190.016
regulation of cellular response to stressGO:00801351590.016
internal peptidyl lysine acetylationGO:0018393420.016
compound eye developmentGO:004874910.016
glycoprotein metabolic processGO:00091001160.016
positive regulation of transferase activityGO:00513471670.015
regulation of establishment of protein localizationGO:00702011810.015
telencephalon developmentGO:00215371860.015
Mouse
regulation of intracellular protein transportGO:0033157820.015
cellular response to molecule of bacterial originGO:0071219830.015
negative regulation of viral transcriptionGO:003289730.015
stem cell maintenanceGO:00198271300.015
Mouse
regulation of cd8 positive alpha beta t cell activationGO:200118530.015
regulation of lymphocyte proliferationGO:00506701170.015
cellular response to external stimulusGO:0071496880.015
peptidyl tyrosine phosphorylationGO:00181081430.015
glycosyl compound metabolic processGO:19016572460.015
Worm
b cell activationGO:00421131610.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
cell fate commitmentGO:00451652100.015
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.014
interferon beta biosynthetic processGO:004535040.014
nuclear transportGO:00511691390.014
positive regulation of lymphocyte mediated immunityGO:0002708620.014
transmission of nerve impulseGO:0019226760.014
positive regulation of apoptotic processGO:00430652170.014
negative regulation of defense responseGO:0031348770.014
cell divisionGO:00513011200.014
Mouse
negative regulation of viral entry into host cellGO:0046597100.014
stem cell developmentGO:00488642190.014
Mouse
entry into other organism involved in symbiotic interactionGO:0051828150.014
carbohydrate catabolic processGO:0016052320.014
protein alkylationGO:0008213810.014
cellular response to peptidoglycanGO:007122440.014
cellular response to hormone stimulusGO:00328701500.014
regulation of chemokine productionGO:0032642300.014
tumor necrosis factor superfamily cytokine productionGO:0071706510.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
Worm
microtubule cytoskeleton organizationGO:00002261570.014
Mouse
negative regulation of homeostatic processGO:0032845710.014
phagocytosisGO:0006909660.014
regulation of hormone levelsGO:00108172110.014
t helper 17 cell lineage commitmentGO:007254040.014
negative regulation of cell developmentGO:00107211690.014
Mouse
gene silencingGO:0016458380.013
Mouse Worm
regulation of ion transportGO:00432692150.013
regulation of dna bindingGO:0051101390.013
cellular amide metabolic processGO:0043603580.013
production of molecular mediator of immune responseGO:00024401030.013
inorganic ion transmembrane transportGO:00986602340.013
negative regulation of leukocyte differentiationGO:1902106510.013
atp catabolic processGO:0006200550.013
Worm
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247640.013
response to organonitrogen compoundGO:00102432460.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.013
cell adhesionGO:00071553290.013
positive regulation of protein catabolic processGO:0045732600.013
divalent inorganic cation transportGO:00725111780.013
angiogenesisGO:00015252010.013
Mouse
antimicrobial peptide biosynthetic processGO:000277720.013
cation transmembrane transportGO:00986552660.013
cellular carbohydrate metabolic processGO:00442621190.013
regulation of myeloid cell differentiationGO:0045637960.013
cellular protein complex assemblyGO:00436231160.013
regulation of lymphocyte mediated immunityGO:0002706840.013
nucleoside monophosphate catabolic processGO:0009125590.013
Worm
regulation of epithelial cell proliferationGO:00506781410.013
regulation of cell motilityGO:20001452360.013
regulation of ossificationGO:00302781120.012
regulation of mapk cascadeGO:00434082480.012
regulation of homeostatic processGO:00328441820.012
regulation of rig i signaling pathwayGO:003953520.012
organic hydroxy compound transportGO:0015850930.012
positive regulation of rig i signaling pathwayGO:190024610.012
regulation of interleukin 12 productionGO:0032655300.012
regulation of hydrolase activityGO:00513362460.012
skeletal system developmentGO:00015013560.012
Mouse
neuron apoptotic processGO:00514021420.012
positive regulation of leukocyte mediated immunityGO:0002705700.012
positive regulation of programmed cell deathGO:00430682180.012
positive regulation of protein phosphorylationGO:00019342420.012
regulation of protein maturationGO:1903317960.012
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.012
response to light stimulusGO:00094161350.012
spermatid differentiationGO:00485151150.012
modification by symbiont of host morphology or physiologyGO:004400340.012
regulation of cytokine productionGO:00018172660.012
muscle cell differentiationGO:00426922610.012
Mouse
ossificationGO:00015032160.012
development of primary sexual characteristicsGO:00451371430.012
lipid biosynthetic processGO:00086101790.012
extracellular matrix organizationGO:00301981470.012
spermatid developmentGO:00072861080.012
response to extracellular stimulusGO:00099911270.012
negative regulation of synapse assemblyGO:005196430.012
neuron deathGO:00709971540.012
regulation of vesicle mediated transportGO:00606271390.012
response to exogenous dsrnaGO:0043330220.012
Mouse
single organism nuclear importGO:1902593950.012
regulation of antimicrobial peptide productionGO:000278410.012
positive regulation of chemokine productionGO:0032722220.012
multicellular organism growthGO:00352641610.012
Mouse
cellular response to extracellular stimulusGO:0031668810.012
regulation of toll like receptor 9 signaling pathwayGO:003416330.012
regulation of cytoskeleton organizationGO:00514931220.012
i kappab kinase nf kappab signalingGO:0007249850.012
lipid transportGO:0006869980.012
rna interferenceGO:001624620.012
Mouse Worm
negative regulation of innate immune responseGO:0045824170.012
positive regulation of cell deathGO:00109422240.011
positive regulation of proteolysisGO:0045862850.011
citrate metabolic processGO:000610130.011
intracellular mrna localizationGO:000829840.011
negative regulation of regulatory t cell differentiationGO:004559020.011
organic hydroxy compound metabolic processGO:19016152030.011
antigen receptor mediated signaling pathwayGO:0050851640.011
regulation of transferase activityGO:00513382630.011
negative regulation of t cell activationGO:0050868650.011
positive regulation of interleukin 6 productionGO:0032755370.011
regulation of carbohydrate metabolic processGO:0006109750.011
translationGO:0006412930.011
intestinal epithelial structure maintenanceGO:006072940.011
regulation of mitotic cell cycleGO:00073461260.011
hexose metabolic processGO:0019318980.011
cellular response to lipopolysaccharideGO:0071222770.011
gonad developmentGO:00084061410.011
type i interferon productionGO:0032606290.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
Worm
negative regulation of protein processingGO:0010955790.011
regulation of defense response to bacteriumGO:190042430.011
mitotic cell cycle processGO:19030471590.011
cell type specific apoptotic processGO:00972852680.011
Mouse
negative regulation of cell activationGO:00508661110.011
toll like receptor 3 signaling pathwayGO:003413840.011
rna processingGO:00063961050.011
Mouse Worm
glucose homeostasisGO:00425931280.011
purine ribonucleoside metabolic processGO:00461282410.011
Worm
interferon alpha productionGO:003260770.011
negative regulation of molecular functionGO:00440922580.011
cellular ion homeostasisGO:00068731650.011
regulation of secretionGO:00510462740.011
defense response to protozoanGO:0042832250.011
regulation of organ morphogenesisGO:20000271440.011
Mouse
nuclear membrane organizationGO:007176340.011
antigen processing and presentation of peptide antigenGO:0048002290.011
positive t cell selectionGO:0043368230.011
appendage developmentGO:00487361660.011
Mouse
purine containing compound biosynthetic processGO:0072522700.011
positive regulation of lymphocyte activationGO:00512511400.011
response to hostGO:007513630.011
negative regulation of interleukin 6 productionGO:0032715170.011
peptide transportGO:00158331330.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.010
regulation of lipid metabolic processGO:00192161180.010
intracellular transport of virusGO:007573310.010
positive regulation of mapk cascadeGO:00434101700.010
positive regulation of toll like receptor 9 signaling pathwayGO:003416520.010
positive regulation of protein import into nucleusGO:0042307260.010
anion transportGO:00068201770.010
positive regulation of cytokine production involved in immune responseGO:0002720190.010
small gtpase mediated signal transductionGO:0007264970.010
regulation of protein kinase activityGO:00458592320.010
multi multicellular organism processGO:00447061090.010
glial cell differentiationGO:00100011310.010
Mouse
alcohol metabolic processGO:00060661160.010
fertilizationGO:00095661270.010
organonitrogen compound catabolic processGO:19015652640.010
Worm
regulation of actin cytoskeleton organizationGO:0032956840.010
regulation of protein targetingGO:1903533610.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.010

Dhx58 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.037
organ system cancerDOID:005068600.037
cancerDOID:16200.037
disease of anatomical entityDOID:700.019
musculoskeletal system diseaseDOID:1700.019
disease of metabolismDOID:001466700.015
acquired metabolic diseaseDOID:006015800.010