| protein modification by small protein removal | GO:0070646 | 21 | 1.000 | Fly |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.982 | Fly |
| mitotic g2 dna damage checkpoint | GO:0007095 | 8 | 0.564 | Fly |
| cell division | GO:0051301 | 120 | 0.521 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.510 | Fly |
| regulation of protein stability | GO:0031647 | 52 | 0.425 | Fly |
| cytokinesis | GO:0000910 | 17 | 0.304 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.277 | Fly |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.275 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.271 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.268 | Fly |
| cellular protein catabolic process | GO:0044257 | 155 | 0.245 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.244 | |
| activation of nf kappab inducing kinase activity | GO:0007250 | 4 | 0.238 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.217 | Fly |
| lateral inhibition | GO:0046331 | 1 | 0.208 | Fly |
| mitotic cell cycle checkpoint | GO:0007093 | 31 | 0.205 | Fly |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.184 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.168 | Fly |
| cell cycle checkpoint | GO:0000075 | 47 | 0.164 | Fly |
| protein ubiquitination | GO:0016567 | 171 | 0.162 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.140 | Fly |
| mapk cascade | GO:0000165 | 281 | 0.136 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.134 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.122 | Fly |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.116 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.113 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.109 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.106 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.104 | |
| protein polymerization | GO:0051258 | 57 | 0.088 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.084 | Fly |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.081 | |
| translational initiation | GO:0006413 | 24 | 0.080 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.078 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.078 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.077 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.075 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.075 | Fly |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.072 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.070 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.068 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.066 | Fly |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.065 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.063 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.057 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.050 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.049 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.049 | |
| nuclear division | GO:0000280 | 158 | 0.049 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.048 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.047 | |
| nik nf kappab signaling | GO:0038061 | 14 | 0.043 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.043 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.041 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.041 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.040 | |
| amine metabolic process | GO:0009308 | 45 | 0.039 | |
| protein stabilization | GO:0050821 | 25 | 0.039 | Fly |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.038 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.038 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.037 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.037 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.036 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.036 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.036 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.036 | |
| rna processing | GO:0006396 | 105 | 0.035 | |
| protein catabolic process | GO:0030163 | 221 | 0.035 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.035 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.035 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.035 | |
| axonogenesis | GO:0007409 | 274 | 0.033 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.032 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.032 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.031 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.031 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.031 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.031 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.031 | |
| mrna metabolic process | GO:0016071 | 84 | 0.030 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.030 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.029 | |
| regulation of cell division | GO:0051302 | 76 | 0.029 | |
| connective tissue development | GO:0061448 | 179 | 0.028 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.027 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.027 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.027 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.027 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.027 | |
| organelle assembly | GO:0070925 | 177 | 0.027 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.026 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.026 | |
| cell fate commitment | GO:0045165 | 210 | 0.025 | Fly |
| mitotic cell cycle | GO:0000278 | 195 | 0.025 | Fly |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.025 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.025 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.025 | |
| stem cell differentiation | GO:0048863 | 268 | 0.024 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.023 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.023 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.023 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.022 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.022 | |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.022 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.021 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.020 | |
| exocytosis | GO:0006887 | 121 | 0.020 | |
| regulation of nik nf kappab signaling | GO:1901222 | 10 | 0.020 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.020 | |
| developmental maturation | GO:0021700 | 193 | 0.020 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.020 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.020 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.020 | |
| gliogenesis | GO:0042063 | 141 | 0.020 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.020 | |
| renal system development | GO:0072001 | 225 | 0.019 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.019 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.019 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.019 | |
| urogenital system development | GO:0001655 | 261 | 0.018 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.018 | |
| skeletal system development | GO:0001501 | 356 | 0.018 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.018 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.018 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.018 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.018 | |
| rhythmic process | GO:0048511 | 174 | 0.018 | |
| organelle localization | GO:0051640 | 179 | 0.018 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.018 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.017 | Fly |
| cytoplasmic translational initiation | GO:0002183 | 3 | 0.017 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.017 | |
| positive regulation of ubiquitin protein transferase activity | GO:0051443 | 4 | 0.017 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.017 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.016 | |
| ubiquitin dependent smad protein catabolic process | GO:0030579 | 2 | 0.016 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.016 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.016 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.016 | Fly |
| oocyte differentiation | GO:0009994 | 35 | 0.016 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.016 | |
| regulation of protein processing | GO:0070613 | 96 | 0.016 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.016 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.016 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.016 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.015 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.015 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.015 | |
| oocyte construction | GO:0007308 | 2 | 0.015 | |
| organelle fission | GO:0048285 | 170 | 0.015 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.015 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.015 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.015 | |
| cell maturation | GO:0048469 | 127 | 0.015 | |
| microtubule based process | GO:0007017 | 236 | 0.015 | |
| establishment of mitotic spindle localization | GO:0040001 | 12 | 0.015 | |
| segmentation | GO:0035282 | 93 | 0.015 | |
| histone modification | GO:0016570 | 159 | 0.015 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.014 | |
| oocyte development | GO:0048599 | 33 | 0.014 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.014 | Fly |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.014 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.014 | |
| germ cell development | GO:0007281 | 185 | 0.014 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.014 | Fly |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.014 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.013 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.013 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.013 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.013 | |
| microtubule polymerization or depolymerization | GO:0031109 | 26 | 0.013 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.013 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.013 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.013 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.013 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.013 | |
| cytokine production | GO:0001816 | 319 | 0.013 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.013 | |
| response to growth factor | GO:0070848 | 198 | 0.012 | |
| stem cell development | GO:0048864 | 219 | 0.012 | |
| gtp catabolic process | GO:0006184 | 143 | 0.012 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.012 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.012 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.012 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.012 | |
| negative regulation of protein catabolic process | GO:0042177 | 36 | 0.012 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.012 | |
| establishment of spindle localization | GO:0051293 | 19 | 0.012 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.012 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.011 | |
| nucleotide sugar metabolic process | GO:0009225 | 4 | 0.011 | |
| gonad development | GO:0008406 | 141 | 0.011 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.011 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.011 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.011 | |
| blastocyst development | GO:0001824 | 80 | 0.011 | |
| spindle localization | GO:0051653 | 22 | 0.011 | |
| substantia nigra development | GO:0021762 | 2 | 0.011 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.011 | |
| regulation of feeding behavior | GO:0060259 | 3 | 0.011 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.010 | |
| microtubule nucleation | GO:0007020 | 2 | 0.010 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.010 | |
| eye photoreceptor cell differentiation | GO:0001754 | 41 | 0.010 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.010 | |
| gland development | GO:0048732 | 330 | 0.010 | |
| jnk cascade | GO:0007254 | 72 | 0.010 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.010 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.010 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.010 | |