Mus musculus

17 known processes

Plk1

polo-like kinase 1 (Drosophila)

(Aliases: STPK13,Plk)

Plk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle assembly involved in mitosisGO:009030740.979
microtubule cytoskeleton organization involved in mitosisGO:190285040.976
microtubule based processGO:00070172360.969
Human Yeast Worm Fly
dna metabolic processGO:00062593030.925
Yeast
organelle assemblyGO:00709251770.913
Yeast Fly
cleavage furrow formationGO:003608920.912
regulation of cell cycle processGO:00105641600.907
Human Yeast Mouse Worm
mitotic cell cycle processGO:19030471590.898
Human Mouse Worm Fly
spindle assemblyGO:0051225130.897
Yeast Fly
cytokinesisGO:0000910170.874
Human Rat Worm Fly
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.864
chromosome segregationGO:0007059480.843
Human Yeast Worm
mitotic cell cycleGO:00002781950.840
Human Zebrafish Mouse Worm Fly
positive regulation of chromosome segregationGO:005198440.837
Human
microtubule cytoskeleton organizationGO:00002261570.830
Human Yeast Worm Fly
microtubule organizing center organizationGO:0031023280.816
Human Yeast Worm Fly
mitotic sister chromatid segregationGO:0000070140.816
Human
positive regulation of mitotic sister chromatid separationGO:190197020.813
Human
cell divisionGO:00513011200.805
Human Rat Worm Fly
regulation of cell divisionGO:0051302760.782
Human Worm
microtubule depolymerizationGO:0007019150.766
regulation of cell cycleGO:00517262810.745
Human Yeast Mouse Worm
nuclear divisionGO:00002801580.734
Human Yeast Rat Worm Fly
centrosome cycleGO:0007098230.734
Worm
meiotic cell cycle processGO:1903046770.733
Yeast Rat Worm Fly
regulation of mitotic cell cycleGO:00073461260.729
Human Mouse
organelle fissionGO:00482851700.707
Human Yeast Rat Worm Fly
centrosome duplicationGO:0051298160.660
metaphase plate congressionGO:005131020.628
meiotic cell cycleGO:00513211220.627
Yeast Rat Worm Fly
organelle localizationGO:00516401790.620
Fly
mitotic cytokinesisGO:000028140.594
Human
regulation of microtubule depolymerizationGO:0031114130.590
regulation of cytoskeleton organizationGO:00514931220.579
Yeast
regulation of spindle organizationGO:009022420.574
positive regulation of mitotic metaphase anaphase transitionGO:004584220.572
Human
regulation of mitotic spindle organizationGO:006023620.524
regulation of microtubule cytoskeleton organizationGO:0070507370.520
Yeast
cytokinetic processGO:003250620.506
Fly
spindle midzone assemblyGO:005125510.497
Fly
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.490
Human
chromatin organizationGO:00063252060.479
mitotic nuclear divisionGO:0007067480.466
Human Worm Fly
sister chromatid segregationGO:0000819200.452
Human
establishment of organelle localizationGO:00516561220.443
Fly
positive regulation of cell cycleGO:0045787920.440
Human Yeast
protein depolymerizationGO:0051261340.436
meiotic cytokinesisGO:003320650.429
Rat Worm Fly
mitotic chromosome condensationGO:000707610.424
meiotic nuclear divisionGO:00071261150.395
Yeast Rat Worm Fly
astral microtubule organizationGO:003095330.392
Fly
negative regulation of organelle organizationGO:0010639900.387
Human
regulation of organelle organizationGO:00330432890.378
Human Yeast Worm
histone serine phosphorylationGO:003540450.376
centrosome separationGO:005129940.375
microtubule based movementGO:0007018840.375
negative regulation of microtubule depolymerizationGO:0007026130.361
cellular protein catabolic processGO:00442571550.359
Human
positive regulation of cell cycle processGO:0090068610.358
Human Yeast
regulation of mitotic cell cycle phase transitionGO:1901990730.357
Human Mouse
regulation of microtubule polymerization or depolymerizationGO:0031110200.352
attachment of spindle microtubules to kinetochoreGO:000860840.338
regulation of exit from mitosisGO:000709610.336
dna endoreduplicationGO:004202340.333
mitotic centrosome separationGO:000710040.333
negative regulation of mitotic cell cycleGO:0045930580.330
Human Mouse
negative regulation of cell cycleGO:00457861230.329
Human Mouse
positive regulation of cellular catabolic processGO:00313311480.327
Human
chromatin modificationGO:00165681870.316
ubiquitin dependent protein catabolic processGO:00065111290.316
Human
response to cell cycle checkpoint signalingGO:007239610.310
regulation of cell cycle phase transitionGO:1901987770.308
Human Mouse
maintenance of locationGO:0051235890.304
g1 s transition of mitotic cell cycleGO:0000082570.298
Mouse
female meiosis chromosome segregationGO:001632110.294
centrosome organizationGO:0051297260.288
Human Worm Fly
microtubule polymerization or depolymerizationGO:0031109260.282
Fly
negative regulation of protein depolymerizationGO:1901880210.278
regulation of mitosisGO:0007088290.274
Human
mitotic sister chromatid cohesionGO:000706410.272
chromosome movement towards spindle poleGO:005130530.272
protein complex disassemblyGO:0043241400.266
spindle localizationGO:0051653220.264
histone modificationGO:00165701590.264
covalent chromatin modificationGO:00165691630.262
spindle organizationGO:0007051280.256
Yeast Worm Fly
protein catabolic processGO:00301632210.256
Human
negative regulation of cell cycle phase transitionGO:1901988480.255
Human Mouse
cell cycle checkpointGO:0000075470.253
Human Mouse
regulation of protein kinase activityGO:00458592320.251
Human
negative regulation of cytoskeleton organizationGO:0051494360.251
histone phosphorylationGO:001657290.236
asymmetric stem cell divisionGO:009872230.233
establishment or maintenance of cell polarityGO:0007163860.232
positive regulation of mitotic cell cycle phase transitionGO:1901992170.215
Human
positive regulation of protein kinase activityGO:00458601440.214
positive regulation of cellular protein catabolic processGO:1903364340.213
Human
development of primary sexual characteristicsGO:00451371430.212
Worm
female meiosis iGO:000714470.211
dephosphorylationGO:00163111290.210
regulation of protein localizationGO:00328802310.198
spindle assembly involved in meiosisGO:009030640.196
Yeast Fly
oocyte maturationGO:0001556180.196
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.194
Human
regulation of kinase activityGO:00435492490.191
Human
macromolecule catabolic processGO:00090572810.187
Human
regulation of protein depolymerizationGO:1901879260.184
protein modification by small protein conjugation or removalGO:00706472070.184
Human
protein modification by small protein conjugationGO:00324461870.179
Human
ras protein signal transductionGO:0007265770.174
modification dependent protein catabolic processGO:00199411330.173
Human
male gamete generationGO:00482322850.172
Fly
positive regulation of protein phosphorylationGO:00019342420.172
Human
peptidyl amino acid modificationGO:00181933360.168
Human
cell cycle comprising mitosis without cytokinesisGO:003330110.167
mitotic spindle organizationGO:0007052100.167
Worm Fly
protein polymerizationGO:0051258570.165
Fly
nucleoside phosphate metabolic processGO:00067533380.165
regulation of cellular component sizeGO:00325351210.163
nucleoside phosphate catabolic processGO:19012922220.161
nuclear envelope organizationGO:0006998110.160
Worm
cellular response to dna damage stimulusGO:00069742070.157
Human Mouse
modification dependent macromolecule catabolic processGO:00436321330.155
Human
cell cycle g2 m phase transitionGO:0044839200.154
Human
cellularizationGO:000734910.151
germ cell developmentGO:00072811850.148
Worm Fly
regulation of bindingGO:00510981110.146
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.145
Human
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.143
regulation of chromosome segregationGO:0051983210.140
Human
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.137
peptidyl serine modificationGO:0018209830.137
Human
negative regulation of phosphorus metabolic processGO:00105631840.134
Human
nucleoside catabolic processGO:00091642060.130
regulation of microtubule based processGO:0032886520.130
Yeast
negative regulation of cell sizeGO:004579230.129
negative regulation of mitotic cell cycle phase transitionGO:1901991450.129
Human Mouse
cellular protein complex assemblyGO:00436231160.129
Fly
ribonucleoside metabolic processGO:00091192450.128
chromosome condensationGO:0030261100.125
male meiosisGO:0007140370.124
Fly
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.123
Human
organonitrogen compound catabolic processGO:19015652640.122
gtp metabolic processGO:00460391440.120
purine nucleoside catabolic processGO:00061522050.120
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.120
Human
microtubule anchoringGO:003445390.117
purine containing compound metabolic processGO:00725213110.116
lateral inhibitionGO:004633110.115
establishment of meiotic spindle orientationGO:005129610.114
regulation of mitotic sister chromatid segregationGO:0033047120.107
Human
nuclear membrane organizationGO:007176340.107
spindle assembly involved in female meiosisGO:000705630.107
Fly
purine ribonucleotide metabolic processGO:00091502900.107
establishment or maintenance of cytoskeleton polarityGO:003095220.105
muscle cell differentiationGO:00426922610.105
dna conformation changeGO:0071103370.105
positive regulation of exit from mitosisGO:003153610.105
female meiotic divisionGO:0007143210.103
Rat Worm Fly
cell cycle g1 s phase transitionGO:0044843570.103
Mouse
metaphase anaphase transition of mitotic cell cycleGO:000709190.103
Human
nucleoside triphosphate metabolic processGO:00091412300.103
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.101
small gtpase mediated signal transductionGO:0007264970.100
protein localization to organelleGO:00333651850.100
Human
g2 m transition of mitotic cell cycleGO:0000086200.100
Human
apoptotic signaling pathwayGO:00971903060.100
reciprocal meiotic recombinationGO:0007131160.097
Yeast
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.097
Human
double strand break repairGO:0006302480.096
positive regulation of protein modification processGO:00314012990.096
Human
establishment of spindle orientationGO:0051294150.095
dna catabolic process exonucleolyticGO:000073830.095
microtubule nucleationGO:000702020.095
Fly
cellular nitrogen compound catabolic processGO:00442702800.094
developmental maturationGO:00217001930.093
regulation of nuclear divisionGO:0051783560.092
Human Worm
regulation of chromosome organizationGO:0033044830.092
Human
positive regulation of mitosisGO:0045840140.090
Human
positive regulation of organelle organizationGO:00106381280.089
Human Yeast
regulation of cytoplasmic transportGO:19036491120.089
regulation of nuclear cell cycle dna replicationGO:003326220.089
positive regulation of mitotic cell cycleGO:0045931410.087
Human
nucleus localizationGO:0051647200.086
Fly
purine ribonucleoside catabolic processGO:00461302050.086
macromolecular complex disassemblyGO:0032984430.084
maintenance of location in cellGO:0051651240.082
nuclear transportGO:00511691390.081
meiosis iGO:0007127600.081
Yeast Worm
positive regulation of proteolysisGO:0045862850.081
Human
peptidyl serine phosphorylationGO:0018105740.081
Human
meiosis iiGO:000713570.080
Worm Fly
regulation of anatomical structure sizeGO:00900661780.080
regulation of b cell tolerance inductionGO:000266120.080
spermatogenesisGO:00072832840.079
Fly
meiotic chromosome segregationGO:0045132190.079
Yeast Worm
ribonucleoside catabolic processGO:00424542060.079
negative regulation of cellular component organizationGO:00511291940.079
Human
purine ribonucleoside metabolic processGO:00461282410.078
neural tube developmentGO:00219151600.077
purine nucleoside metabolic processGO:00422782410.077
heterocycle catabolic processGO:00467002800.076
nucleosome disassemblyGO:000633710.075
dna recombinationGO:0006310920.074
Yeast
dna packagingGO:0006323300.073
cellular protein complex disassemblyGO:0043624360.072
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.071
nuclear dna replicationGO:003326030.071
centriole assemblyGO:009853460.071
digestive tract developmentGO:00485651900.071
ribonucleoside triphosphate metabolic processGO:00091992200.070
cellular macromolecule catabolic processGO:00442652060.069
Human
fertilizationGO:00095661270.068
Fly
ribose phosphate metabolic processGO:00196932910.068
regulation of protein serine threonine kinase activityGO:00719001570.068
Human
positive regulation of chromosome organizationGO:2001252330.068
Human
nucleoside metabolic processGO:00091162460.067
purine nucleotide metabolic processGO:00061633020.066
intracellular protein transportGO:00068862040.066
regulation of transferase activityGO:00513382630.066
Human
organic cyclic compound catabolic processGO:19013612950.066
nucleobase containing small molecule metabolic processGO:00550863520.065
cyclin catabolic processGO:000805410.065
dna repairGO:00062811070.064
cellular amino acid metabolic processGO:00065201030.064
establishment of protein localization to organelleGO:00725941180.064
positive regulation of nucleoside metabolic processGO:0045979910.063
regulation of cell sizeGO:0008361720.063
sister chromatid cohesionGO:0007062120.062
rho protein signal transductionGO:0007266320.062
negative regulation of gene expression epigeneticGO:0045814150.062
cellular component assembly involved in morphogenesisGO:00109271390.062
single fertilizationGO:0007338820.061
Fly
ventricular cardiac muscle cell developmentGO:0055015110.060
nucleotide metabolic processGO:00091173320.060
purine containing compound catabolic processGO:00725232130.060
negative regulation of mitosisGO:0045839100.059
Human
regulation of protein transportGO:00512231630.058
multicellular organism growthGO:00352641610.058
endocytosisGO:00068971680.057
Fly
embryonic epithelial tube formationGO:00018381300.057
gonad developmentGO:00084061410.057
Worm
synapsisGO:0007129340.057
mitotic sister chromatid separationGO:005130690.057
Human
regulation of purine nucleotide catabolic processGO:00331211220.056
gene silencingGO:0016458380.056
negative regulation of cell cycle processGO:0010948690.056
Human Mouse
regulation of proteolysisGO:00301621640.056
Human
negative regulation of cellular protein metabolic processGO:00322692470.054
Human
regulation of cytokinesisGO:003246550.052
negative regulation of molecular functionGO:00440922580.052
Human
protein ubiquitinationGO:00165671710.052
Human
purine nucleotide catabolic processGO:00061952110.051
endomembrane system organizationGO:00102561470.051
Worm
organophosphate catabolic processGO:00464342320.051
membrane disassemblyGO:003039710.050
Worm
nucleotide catabolic processGO:00091662170.050
gland developmentGO:00487323300.049
aromatic compound catabolic processGO:00194392860.049
regulation of nucleoside metabolic processGO:00091181300.049
dna replicationGO:0006260520.049
dna biosynthetic processGO:0071897220.049
oocyte developmentGO:0048599330.049
translesion synthesisGO:001998510.048
spindle assembly involved in female meiosis iGO:000705720.048
proteolysis involved in cellular protein catabolic processGO:00516031470.048
Human
cell fate commitmentGO:00451652100.047
Fly
purine nucleoside triphosphate metabolic processGO:00091442260.046
negative regulation of proteolysisGO:0045861740.046
Human
positive regulation of kinase activityGO:00336741550.046
response to organic cyclic compoundGO:00140701980.046
proteasomal protein catabolic processGO:0010498980.045
Human
purine ribonucleoside triphosphate metabolic processGO:00092052200.045
myosin filament organizationGO:003103330.045
glycosyl compound metabolic processGO:19016572460.044
nucleoside triphosphate catabolic processGO:00091432050.044
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.044
Human
oocyte differentiationGO:0009994350.043
Fly
regulation of protein complex disassemblyGO:0043244280.042
single organism nuclear importGO:1902593950.042
positive regulation of cellular amino acid metabolic processGO:004576430.042
regulation of ras gtpase activityGO:0032318880.041
regulation of cell motilityGO:20001452360.041
regulation of intracellular protein transportGO:0033157820.041
cellular homeostasisGO:00197252400.041
homeostasis of number of cellsGO:00488722100.041
cardiac muscle cell differentiationGO:0055007690.040
positive regulation of cellular amine metabolic processGO:003324050.040
cation transportGO:00068123990.040
dendrite developmentGO:00163581150.040
cytoplasmic transportGO:00164822340.040
cell agingGO:0007569350.040
muscle tissue developmentGO:00605373080.040
protein localization to nucleusGO:00345041210.040
dna integrity checkpointGO:0031570280.040
Human
striated muscle tissue developmentGO:00147062930.040
negative regulation of protein complex disassemblyGO:0043242220.039
positive regulation of cell deathGO:00109422240.039
regulation of cellular catabolic processGO:00313292420.039
Human
protein importGO:00170381010.039
chromatin remodeling at centromereGO:003105520.039
guanosine containing compound metabolic processGO:19010681440.039
regulation of apoptotic signaling pathwayGO:20012331970.038
chromosome separationGO:0051304140.038
Human Yeast
regulation of cell cycle g1 s phase transitionGO:1902806350.038
Mouse
nuclear migrationGO:000709760.038
Fly
protein targetingGO:00066051430.038
stem cell developmentGO:00488642190.037
positive regulation of chromatin modificationGO:1903310280.037
dna dependent dna replicationGO:0006261240.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
neural tube formationGO:00018411080.036
negative regulation of protein modification processGO:00314001630.036
Human
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.036
Human
regulation of metaphase anaphase transition of cell cycleGO:190209990.035
Human
regulation of cellular response to stressGO:00801351590.035
regulation of cellular amine metabolic processGO:0033238200.035
mitotic cell cycle checkpointGO:0007093310.035
Human Mouse
t cell differentiationGO:00302171740.035
positive regulation of ubiquitin protein transferase activityGO:005144340.034
Human
positive regulation of protein serine threonine kinase activityGO:00719021060.034
primary neural tube formationGO:0014020950.034
cellular response to sterol depletionGO:007150140.034
body morphogenesisGO:0010171450.034
regulation of cellular protein catabolic processGO:1903362610.033
Human
positive regulation of purine nucleotide metabolic processGO:19005441140.033
negative regulation of phosphate metabolic processGO:00459361840.033
Human
protein localization to chromosomeGO:003450260.032
Human
positive regulation of protein catabolic processGO:0045732600.032
Human
protein localization to chromosome centromeric regionGO:007145910.032
regulation of protein bindingGO:0043393600.032
Human
regulation of establishment of protein localizationGO:00702011810.032
regulation of ran gtpase activityGO:003231630.032
glycosyl compound catabolic processGO:19016582060.032
myosin filament assemblyGO:003103420.032
regulation of secretionGO:00510462740.032
response to radiationGO:00093141650.031
negative regulation of centrosome duplicationGO:001082640.031
positive regulation of purine nucleotide catabolic processGO:0033123880.031
oogenesisGO:0048477560.031
Worm Fly
actin filament polymerizationGO:0030041440.031
maintenance of protein location in cellGO:0032507200.031
regulation of intracellular transportGO:00323861590.030
cellular ketone metabolic processGO:0042180840.030
peptidyl threonine phosphorylationGO:0018107310.030
Human
positive regulation of nucleotide metabolic processGO:00459811140.030
digestive system developmentGO:00551232000.030
regulation of protein processingGO:0070613960.030
Human
multicellular organismal agingGO:0010259240.030
regulation of protein import into nucleusGO:0042306520.030
negative regulation of apoptotic signaling pathwayGO:20012341040.030
regulation of purine nucleotide metabolic processGO:19005421690.030
protein localization to nuclear envelopeGO:009043520.030
regulation of gtp catabolic processGO:00331241130.029
positive regulation of hydrolase activityGO:00513451480.029
intrinsic apoptotic signaling pathwayGO:00971931320.029
negative regulation of mitotic metaphase anaphase transitionGO:004584170.029
Human
regulation of dephosphorylationGO:0035303180.029
carbohydrate derivative catabolic processGO:19011362310.029
protein maturationGO:00516041760.029
Human
nucleus organizationGO:0006997450.029
Worm Fly
mapk cascadeGO:00001652810.029
purine nucleoside triphosphate catabolic processGO:00091462030.028
srebp signaling pathwayGO:003293340.028
stem cell differentiationGO:00488632680.028
asymmetric neuroblast divisionGO:005505910.028
cell maturationGO:00484691270.028
purine ribonucleoside monophosphate catabolic processGO:0009169570.028
stem cell maintenanceGO:00198271300.028
positive regulation of programmed cell deathGO:00430682180.028
gtp catabolic processGO:00061841430.028
negative regulation of cell agingGO:009034450.028
establishment of spindle localizationGO:0051293190.028
regulation of protein complex assemblyGO:0043254830.027
cardiocyte differentiationGO:0035051870.027
ribonucleotide metabolic processGO:00092592910.027
response to iron ionGO:001003940.027
positive regulation of gtpase activityGO:0043547850.027
microtubule polymerizationGO:0046785120.027
Fly
positive regulation of fibroblast proliferationGO:0048146200.026
regulation of cytokine productionGO:00018172660.026
actin cytoskeleton organizationGO:00300362200.026
Fly
dna dependent dna replication maintenance of fidelityGO:004500530.026
positive regulation of nfat protein import into nucleusGO:005153310.026
female gamete generationGO:0007292740.026
Worm Fly
peptidyl tyrosine dephosphorylationGO:0035335230.026
fibroblast proliferationGO:0048144350.026
membrane organizationGO:00610242450.026
Worm
tube closureGO:0060606910.025
purine ribonucleotide catabolic processGO:00091542080.025
positive regulation of apoptotic processGO:00430652170.025
posttranscriptional regulation of gene expressionGO:00106081550.025
Human
epithelial tube morphogenesisGO:00605623030.025
protein autophosphorylationGO:0046777610.025
positive regulation of transferase activityGO:00513471670.025
Human
genitalia developmentGO:0048806370.025
Worm
ribonucleoside triphosphate catabolic processGO:00092031990.025
negative regulation of cell proliferationGO:00082852960.025
Mouse Fly
synaptonemal complex assemblyGO:0007130130.025
regulation of fibroblast proliferationGO:0048145340.025
regulation of proteasomal protein catabolic processGO:0061136460.024
Human
cellular amine metabolic processGO:0044106440.024
regulation of rho protein signal transductionGO:0035023710.024
regulation of actin filament based processGO:0032970990.024
response to light stimulusGO:00094161350.024
regulation of nucleotide metabolic processGO:00061401690.024
signal transduction by p53 class mediatorGO:0072331510.024
regulation of dna dependent dna replicationGO:009032980.024
positive regulation of gtp catabolic processGO:0033126850.024
regulation of cellular amino acid metabolic processGO:000652150.023
negative regulation of protein metabolic processGO:00512482820.023
Human
lymphocyte differentiationGO:00300982420.023
histone threonine phosphorylationGO:003540510.023
regulation of hydrolase activityGO:00513362460.023
regulation of g1 s transition of mitotic cell cycleGO:2000045350.023
Mouse
leukocyte differentiationGO:00025213420.022
protein import into nucleusGO:0006606950.022
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.022
reactive oxygen species metabolic processGO:0072593840.022
regulation of actin polymerization or depolymerizationGO:0008064450.022
regulation of asymmetric cell divisionGO:000978640.022
regulation of double strand break repair via homologous recombinationGO:001056920.021
positive regulation of mitotic cell cycle embryonicGO:004597720.021
regulation of cell migrationGO:00303342190.021
response to uvGO:0009411440.021
wnt signaling pathwayGO:00160551880.021
cytokine productionGO:00018163190.021
neuron migrationGO:00017641220.021
regulation of nucleotide catabolic processGO:00308111220.020
regulation of actin cytoskeleton organizationGO:0032956840.020
regulation of rho gtpase activityGO:0032319580.020
muscle cell developmentGO:00550011330.020
nuclear importGO:0051170950.020
regulation of cellular component biogenesisGO:00440871810.020
regulation of double strand break repair via nonhomologous end joiningGO:200103220.020
negative regulation of protein maturationGO:1903318790.020
Human
regulation of multi organism processGO:00439001110.020
actin polymerization or depolymerizationGO:0008154540.019
mitotic spindle checkpointGO:007117490.019
Human
negative regulation of intracellular protein transportGO:0090317270.019
morphogenesis of embryonic epitheliumGO:00163311590.019
meiotic spindle organizationGO:000021290.019
Yeast Fly
regulation of lymphocyte differentiationGO:00456191070.019
striated muscle myosin thick filament assemblyGO:007168810.019
regulation of mitotic metaphase anaphase transitionGO:003007180.019
Human
response to steroid hormoneGO:0048545560.018
oxidation reduction processGO:00551143420.018
thymus developmentGO:0048538410.018
regulation of homeostatic processGO:00328441820.018
nucleocytoplasmic transportGO:00069131390.018
cell cycle switching mitotic to meiotic cell cycleGO:005172810.018
positive regulation of cell divisionGO:0051781310.018
Human
blood vessel morphogenesisGO:00485142850.018
positive regulation of oocyte maturationGO:190019520.018
negative regulation of intracellular transportGO:0032387380.018
guanosine containing compound catabolic processGO:19010691440.018
regulation of protein targetingGO:1903533610.017
leukocyte homeostasisGO:0001776790.017
digestive tract morphogenesisGO:00485461470.017
regulation of ras protein signal transductionGO:00465781140.017
positive regulation of growthGO:00459271040.017
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.017
Human
positive regulation of nuclear divisionGO:0051785270.017
Human
protein processingGO:00164851630.017
Human
negative regulation of protein processingGO:0010955790.017
Human
epithelial tube formationGO:00721751300.017
synaptonemal complex organizationGO:0070193150.017
Yeast
regulation of nucleocytoplasmic transportGO:0046822730.017
positive regulation of nervous system developmentGO:00519622210.017
Mouse
cell cycle arrestGO:0007050370.017
positive regulation of reproductive processGO:2000243190.016
citrate metabolic processGO:000610130.016
negative regulation of bindingGO:0051100390.016
regulation of cellular ketone metabolic processGO:0010565660.016
regulation of ubiquitin protein transferase activityGO:005143870.016
Human
anatomical structure homeostasisGO:00602491450.016
purine nucleoside monophosphate catabolic processGO:0009128580.016
regulation of response to dna damage stimulusGO:2001020340.016
nitrogen compound transportGO:00717052710.016
positive regulation of cytoplasmic transportGO:1903651400.015
positive regulation of synaptic plasticityGO:003191540.015
neural tube closureGO:0001843900.015
exit from mitosisGO:001045830.015

Plk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.097
disease of cellular proliferationDOID:1456600.097
organ system cancerDOID:005068600.091
gastrointestinal system cancerDOID:311900.081
intestinal cancerDOID:1015500.053
large intestine cancerDOID:567200.043
hematopoietic system diseaseDOID:7400.023
blood platelet diseaseDOID:221800.023
blood coagulation diseaseDOID:124700.023
disease of anatomical entityDOID:700.023
hemorrhagic diseaseDOID:221300.023
immune system diseaseDOID:291400.023