Mus musculus

84 known processes

Plk5

polo-like kinase 5 (Drosophila)

(Aliases: MGC106082,6330514A18Rik)

Plk5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.266
cation transportGO:00068123990.227
cation transmembrane transportGO:00986552660.107
inorganic ion transmembrane transportGO:00986602340.091
organic anion transportGO:00157111370.084
inorganic cation transmembrane transportGO:00986622070.084
regulation of transmembrane transportGO:00347621280.083
transmembrane transportGO:00550854120.075
regulation of cellular amino acid metabolic processGO:000652150.073
regulation of ion transmembrane transportGO:00347651190.071
synaptic transmissionGO:00072683290.070
Mouse
negative regulation of cellular amine metabolic processGO:003323910.056
divalent metal ion transportGO:00708381720.056
cellular amino acid metabolic processGO:00065201030.055
detection of stimulusGO:0051606840.055
anion transportGO:00068201770.054
divalent inorganic cation transportGO:00725111780.047
phototransductionGO:0007602170.044
cognitionGO:00508901490.038
Mouse
regulation of voltage gated calcium channel activityGO:190138540.037
nucleoside phosphate metabolic processGO:00067533380.037
cellular chemical homeostasisGO:00550822150.036
axonogenesisGO:00074092740.036
cellular ketone metabolic processGO:0042180840.035
nitrogen compound transportGO:00717052710.035
regulation of ion transportGO:00432692150.034
calcium ion transmembrane transportGO:0070588850.034
neurotransmitter transportGO:0006836760.034
regulation of cellular ketone metabolic processGO:0010565660.034
peptidyl amino acid modificationGO:00181933360.034
microtubule based processGO:00070172360.033
Yeast
amino acid transportGO:0006865610.032
response to organic cyclic compoundGO:00140701980.031
organic acid transportGO:00158491010.031
chemotaxisGO:00069352470.029
calcium ion transportGO:00068161590.029
regulation of neurotransmitter levelsGO:0001505870.029
cellular lipid metabolic processGO:00442553230.028
establishment of organelle localizationGO:00516561220.028
positive regulation of protein phosphorylationGO:00019342420.028
membrane organizationGO:00610242450.028
carboxylic acid transportGO:00469421000.028
nucleotide metabolic processGO:00091173320.027
positive regulation of cilium movementGO:000335310.027
negative regulation of cellular amino acid metabolic processGO:004576300.026
nucleobase containing small molecule metabolic processGO:00550863520.026
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activityGO:2000311110.026
organelle localizationGO:00516401790.026
endomembrane system organizationGO:00102561470.026
neuron neuron synaptic transmissionGO:0007270690.025
regulation of cellular amine metabolic processGO:0033238200.025
learningGO:0007612980.025
plasma membrane organizationGO:0007009900.024
nuclear divisionGO:00002801580.024
Yeast
regulation of homeostatic processGO:00328441820.024
establishment of vesicle localizationGO:0051650810.024
regulation of glutamate receptor signaling pathwayGO:1900449160.023
regulation of transporter activityGO:0032409570.023
cation homeostasisGO:00550802120.023
photoreceptor cell developmentGO:0042461400.022
synaptic vesicle transportGO:0048489570.022
negative regulation of molecular functionGO:00440922580.022
lateral inhibitionGO:004633110.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
mitochondrion organizationGO:00070051340.022
neurotransmitter secretionGO:0007269620.022
regulation of secretionGO:00510462740.022
metal ion homeostasisGO:00550651890.021
cellular amine metabolic processGO:0044106440.021
negative regulation of cell proliferationGO:00082852960.021
sodium ion transmembrane transportGO:0035725490.021
ribose phosphate metabolic processGO:00196932910.021
positive regulation of nervous system developmentGO:00519622210.021
organophosphate catabolic processGO:00464342320.020
amine metabolic processGO:0009308450.020
cellular homeostasisGO:00197252400.020
regulation of kinase activityGO:00435492490.020
sequestering of calcium ionGO:0051208180.020
peptide secretionGO:00027901140.020
sensory perception of light stimulusGO:0050953540.020
peptidyl tyrosine modificationGO:00182121450.020
ribonucleotide metabolic processGO:00092592910.020
regulation of transferase activityGO:00513382630.020
regulation of organelle organizationGO:00330432890.019
Yeast
calcium ion homeostasisGO:00550741270.019
activation of immune responseGO:00022531380.019
regulation of hormone levelsGO:00108172110.019
regulation of purine nucleotide metabolic processGO:19005421690.019
multicellular organismal homeostasisGO:00488711640.019
protein localization to organelleGO:00333651850.019
regulation of nucleotide metabolic processGO:00061401690.019
vesicle localizationGO:0051648860.019
regulation of protein kinase activityGO:00458592320.018
spermatogenesisGO:00072832840.018
cell recognitionGO:0008037830.018
reactive oxygen species metabolic processGO:0072593840.018
synapse organizationGO:00508081250.018
glycoprotein metabolic processGO:00091001160.018
purine ribonucleotide catabolic processGO:00091542080.018
synaptic vesicle localizationGO:0097479590.018
aromatic compound catabolic processGO:00194392860.017
purine nucleotide metabolic processGO:00061633020.017
substantia nigra developmentGO:002176220.017
cell adhesionGO:00071553290.017
regulation of ion transmembrane transporter activityGO:0032412540.017
maintenance of locationGO:0051235890.017
peptide transportGO:00158331330.016
purine nucleoside metabolic processGO:00422782410.016
hormone secretionGO:00468791280.016
camera type eye developmentGO:00430102660.016
negative regulation of phosphate metabolic processGO:00459361840.016
negative regulation of phosphorylationGO:00423261660.016
heterocycle catabolic processGO:00467002800.016
mammary gland bud formationGO:006061520.016
actin cytoskeleton organizationGO:00300362200.016
purine containing compound metabolic processGO:00725213110.015
sodium ion transportGO:0006814730.015
purine ribonucleotide metabolic processGO:00091502900.015
response to light stimulusGO:00094161350.015
alpha amino acid metabolic processGO:1901605590.015
regulation of membrane potentialGO:00423911920.015
cellular nitrogen compound catabolic processGO:00442702800.015
learning or memoryGO:00076111480.015
Mouse
sulfur compound metabolic processGO:00067901000.015
amide transportGO:00428861380.015
regulation of system processGO:00440572000.015
regulation of neuronal synaptic plasticityGO:0048168300.015
intracellular protein transportGO:00068862040.015
ribonucleoside metabolic processGO:00091192450.014
inorganic anion transportGO:0015698430.014
regulation of hormone secretionGO:0046883880.014
establishment of synaptic vesicle localizationGO:0097480570.014
mapk cascadeGO:00001652810.014
regulation of synaptic plasticityGO:0048167870.014
Mouse
cellular calcium ion homeostasisGO:00068741190.014
positive regulation of protein modification processGO:00314012990.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
fat soluble vitamin biosynthetic processGO:004236240.014
cytoplasmic transportGO:00164822340.014
glutamate receptor signaling pathwayGO:0007215350.014
response to radiationGO:00093141650.014
regulation of metal ion transportGO:00109591060.014
oxidation reduction processGO:00551143420.013
organonitrogen compound catabolic processGO:19015652640.013
photoreceptor cell differentiationGO:0046530520.013
negative regulation of protein metabolic processGO:00512482820.013
cellular response to abiotic stimulusGO:0071214560.013
retina development in camera type eyeGO:00600411190.013
locomotory behaviorGO:00076261950.013
potassium ion transmembrane transportGO:0071805430.013
positive regulation of kinase activityGO:00336741550.013
nucleoside monophosphate metabolic processGO:0009123850.013
regulation of neuron projection developmentGO:00109751690.013
male gamete generationGO:00482322850.013
lipid transportGO:0006869980.013
peptide hormone secretionGO:00300721090.013
lipid localizationGO:00108761260.013
carbohydrate derivative biosynthetic processGO:19011371830.012
positive regulation of secretionGO:00510471300.012
protein modification by small protein conjugation or removalGO:00706472070.012
sensory organ morphogenesisGO:00905962420.012
regulation of purine nucleotide catabolic processGO:00331211220.012
one carbon metabolic processGO:000673010.012
negative regulation of protein phosphorylationGO:00019331260.012
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
cellular ion homeostasisGO:00068731650.012
eye photoreceptor cell differentiationGO:0001754410.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
kidney developmentGO:00018222130.012
organelle fissionGO:00482851700.012
Yeast
renal system developmentGO:00720012250.012
meiotic nuclear divisionGO:00071261150.012
Yeast
regulation of reactive oxygen species biosynthetic processGO:190342620.012
regulation of cell cycle processGO:00105641600.012
carbohydrate metabolic processGO:00059752300.012
cellular response to organonitrogen compoundGO:00714171450.012
regulation of proteolysisGO:00301621640.012
divalent inorganic cation homeostasisGO:00725071380.012
nuclear transportGO:00511691390.011
regulation of calcium ion transportGO:0051924690.011
anatomical structure homeostasisGO:00602491450.011
glucose homeostasisGO:00425931280.011
microtubule cytoskeleton organizationGO:00002261570.011
Yeast
nucleoside metabolic processGO:00091162460.011
positive regulation of protein kinase activityGO:00458601440.011
positive regulation of long term neuronal synaptic plasticityGO:004817030.011
regulation of gamma aminobutyric acid secretionGO:001405220.011
transmission of nerve impulseGO:0019226760.011
regulation of receptor activityGO:0010469410.011
posttranscriptional regulation of gene expressionGO:00106081550.011
nucleocytoplasmic transportGO:00069131390.011
reactive nitrogen species metabolic processGO:200105700.011
regulation of peptide secretionGO:0002791770.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
ribonucleoside catabolic processGO:00424542060.011
protein autophosphorylationGO:0046777610.011
regulation of cell motilityGO:20001452360.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
phosphatidylinositol metabolic processGO:0046488450.011
adult behaviorGO:00305341350.011
regulation of high voltage gated calcium channel activityGO:190184120.011
protein palmitoylationGO:0018345140.011
regulation of cell cycleGO:00517262810.011
cellular response to acid chemicalGO:0071229680.011
nucleoside phosphate catabolic processGO:19012922220.010
protein oligomerizationGO:0051259670.010
cilium morphogenesisGO:00602711020.010
regulation of anion transportGO:0044070270.010
regulation of neurotransmitter transportGO:0051588350.010
wnt signaling pathwayGO:00160551880.010
exocytosisGO:00068871210.010
tube formationGO:00351481400.010
rap protein signal transductionGO:003248630.010
glycosyl compound metabolic processGO:19016572460.010
regulation of body fluid levelsGO:00508781620.010
cellular potassium ion transportGO:0071804430.010
protein targetingGO:00066051430.010
response to organonitrogen compoundGO:00102432460.010
spermatid differentiationGO:00485151150.010

Plk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.078
sensory system diseaseDOID:005015500.078
disease of anatomical entityDOID:700.078
eye and adnexa diseaseDOID:149200.044
eye diseaseDOID:561400.044
retinal degenerationDOID:846600.018
retinal diseaseDOID:567900.018
retinitis pigmentosaDOID:1058400.014
central nervous system diseaseDOID:33100.012
cardiovascular system diseaseDOID:128700.011