Mus musculus

57 known processes

Sptlc1

serine palmitoyltransferase, long chain base subunit 1

(Aliases: E030036H05,Lcb1,C77762,AW552086)

Sptlc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amino acid metabolic processGO:000652150.084
cellular amine metabolic processGO:0044106440.067
cellular amino acid metabolic processGO:00065201030.063
amine metabolic processGO:0009308450.052
transmembrane transportGO:00550854120.051
regulation of cellular ketone metabolic processGO:0010565660.048
cellular ketone metabolic processGO:0042180840.046
ion transmembrane transportGO:00342203610.045
cellular lipid metabolic processGO:00442553230.042
cation transportGO:00068123990.042
positive regulation of cellular amino acid metabolic processGO:004576430.039
endocytosisGO:00068971680.038
engulfment of apoptotic cellGO:004365230.035
regulation of cellular amine metabolic processGO:0033238200.034
intracellular protein transportGO:00068862040.033
cytoplasmic transportGO:00164822340.032
protein modification by small protein conjugation or removalGO:00706472070.032
cation homeostasisGO:00550802120.032
positive regulation of secretionGO:00510471300.031
leukocyte differentiationGO:00025213420.030
endomembrane system organizationGO:00102561470.030
oxidation reduction processGO:00551143420.030
protein modification by small protein conjugationGO:00324461870.030
membrane organizationGO:00610242450.029
organonitrogen compound biosynthetic processGO:19015661920.028
apoptotic signaling pathwayGO:00971903060.028
macromolecule catabolic processGO:00090572810.028
cellular homeostasisGO:00197252400.027
positive regulation of cellular amine metabolic processGO:003324050.026
nucleobase containing small molecule metabolic processGO:00550863520.026
cation transmembrane transportGO:00986552660.026
nucleoside phosphate metabolic processGO:00067533380.026
monocarboxylic acid metabolic processGO:00327871910.026
negative regulation of protein metabolic processGO:00512482820.025
asymmetric stem cell divisionGO:009872230.025
cellular chemical homeostasisGO:00550822150.024
vesicle organizationGO:0016050600.024
negative regulation of cellular amine metabolic processGO:003323910.023
compound eye developmentGO:004874910.023
purine nucleotide metabolic processGO:00061633020.023
protein ubiquitinationGO:00165671710.023
nucleotide metabolic processGO:00091173320.023
lipid transportGO:0006869980.022
cellular ion homeostasisGO:00068731650.021
anion transportGO:00068201770.021
cytokine productionGO:00018163190.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
immune effector processGO:00022523210.021
carbohydrate derivative biosynthetic processGO:19011371830.021
nucleoside triphosphate catabolic processGO:00091432050.021
nucleoside phosphate catabolic processGO:19012922220.021
nitrogen compound transportGO:00717052710.020
organonitrogen compound catabolic processGO:19015652640.020
regulation of secretionGO:00510462740.020
modification dependent macromolecule catabolic processGO:00436321330.020
carbohydrate metabolic processGO:00059752300.020
aromatic compound catabolic processGO:00194392860.020
cellular metal ion homeostasisGO:00068751510.020
protein catabolic processGO:00301632210.020
organic anion transportGO:00157111370.020
metal ion homeostasisGO:00550651890.020
cellular macromolecule catabolic processGO:00442652060.020
regulation of organelle organizationGO:00330432890.020
ribonucleotide metabolic processGO:00092592910.019
purine nucleotide catabolic processGO:00061952110.019
regulation of membrane potentialGO:00423911920.019
peptidyl amino acid modificationGO:00181933360.019
sequestering of metal ionGO:0051238190.019
regulation of secretion by cellGO:19035302490.019
synaptic transmissionGO:00072683290.019
nucleotide transmembrane transportGO:190167920.018
response to nutrient levelsGO:00316671090.018
regulation of protein localizationGO:00328802310.018
regulation of cell activationGO:00508652890.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
homeostasis of number of cellsGO:00488722100.018
ubiquitin dependent protein catabolic processGO:00065111290.018
regulation of cell cycleGO:00517262810.018
asymmetric neuroblast divisionGO:005505910.018
transmission of nerve impulseGO:0019226760.018
inorganic ion transmembrane transportGO:00986602340.018
purine containing compound metabolic processGO:00725213110.018
sequestering of calcium ionGO:0051208180.018
lateral inhibitionGO:004633110.017
multicellular organismal signalingGO:0035637910.017
vacuole organizationGO:0007033380.017
divalent inorganic cation transportGO:00725111780.017
positive regulation of protein modification processGO:00314012990.017
regulation of vesicle mediated transportGO:00606271390.017
inorganic cation transmembrane transportGO:00986622070.017
cell type specific apoptotic processGO:00972852680.017
organic hydroxy compound metabolic processGO:19016152030.017
heterocycle catabolic processGO:00467002800.017
cellular protein catabolic processGO:00442571550.017
regulation of establishment of protein localizationGO:00702011810.017
ras protein signal transductionGO:0007265770.017
ribose phosphate metabolic processGO:00196932910.016
nucleoside metabolic processGO:00091162460.016
cellular nitrogen compound catabolic processGO:00442702800.016
organelle localizationGO:00516401790.016
regulation of lymphocyte activationGO:00512492400.016
inflammatory responseGO:00069542440.016
regulation of homeostatic processGO:00328441820.016
purine nucleoside catabolic processGO:00061522050.016
negative regulation of cellular protein metabolic processGO:00322692470.016
regulation of ion transportGO:00432692150.016
digestive system developmentGO:00551232000.016
glycosyl compound metabolic processGO:19016572460.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
protein localization to organelleGO:00333651850.016
negative regulation of immune system processGO:00026832090.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
multicellular organism growthGO:00352641610.016
retrograde transport endosome to golgiGO:004214720.016
glycoprotein biosynthetic processGO:0009101890.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
purine containing compound catabolic processGO:00725232130.016
modification dependent protein catabolic processGO:00199411330.015
protein secretionGO:00093061110.015
divalent metal ion transportGO:00708381720.015
dna metabolic processGO:00062593030.015
male gamete generationGO:00482322850.015
fatty acid metabolic processGO:00066311210.015
cellular response to cytokine stimulusGO:00713451890.015
lymphocyte differentiationGO:00300982420.015
cellular response to lipidGO:00713961450.015
carbohydrate derivative catabolic processGO:19011362310.015
divalent inorganic cation homeostasisGO:00725071380.015
regulation of cytokine productionGO:00018172660.015
maintenance of locationGO:0051235890.015
mitochondrion organizationGO:00070051340.014
phagocytosisGO:0006909660.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
cognitionGO:00508901490.014
ribonucleoside metabolic processGO:00091192450.014
calcium ion transportGO:00068161590.014
positive regulation of lymphocyte activationGO:00512511400.014
protein targetingGO:00066051430.014
rho protein signal transductionGO:0007266320.014
purine ribonucleotide metabolic processGO:00091502900.014
innate immune responseGO:00450871570.014
cellular response to lipopolysaccharideGO:0071222770.014
rna processingGO:00063961050.014
regulation of cell projection organizationGO:00313442060.014
respiratory system developmentGO:00605411900.014
sphingolipid biosynthetic processGO:0030148260.014
positive regulation of secretion by cellGO:19035321140.014
neuron apoptotic processGO:00514021420.014
cofactor transportGO:005118140.013
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.013
anion transmembrane transportGO:0098656710.013
regulation of hormone levelsGO:00108172110.013
purine ribonucleoside metabolic processGO:00461282410.013
organic cyclic compound catabolic processGO:19013612950.013
carboxylic acid transportGO:00469421000.013
regulation of t cell activationGO:00508631700.013
protein maturationGO:00516041760.013
calcium ion homeostasisGO:00550741270.013
response to lipopolysaccharideGO:00324961280.013
regulation of interleukin 8 productionGO:003267730.013
cellular response to biotic stimulusGO:0071216920.013
negative regulation of cellular component organizationGO:00511291940.013
positive regulation of dna templated transcription elongationGO:003278620.013
organophosphate catabolic processGO:00464342320.013
skin developmentGO:00435882200.013
t cell activationGO:00421102890.013
wnt signaling pathwayGO:00160551880.013
glycerolipid metabolic processGO:00464861220.013
posttranscriptional regulation of gene expressionGO:00106081550.013
mitotic cell cycleGO:00002781950.013
negative regulation of molecular functionGO:00440922580.013
spermatogenesisGO:00072832840.013
reactive oxygen species metabolic processGO:0072593840.013
response to endoplasmic reticulum stressGO:0034976530.013
carbohydrate homeostasisGO:00335001280.013
lipid biosynthetic processGO:00086101790.013
response to extracellular stimulusGO:00099911270.013
dna templated transcriptional preinitiation complex assemblyGO:007089740.013
cellular response to dna damage stimulusGO:00069742070.013
activation of immune responseGO:00022531380.012
anatomical structure homeostasisGO:00602491450.012
microtubule based processGO:00070172360.012
protein processingGO:00164851630.012
response to organonitrogen compoundGO:00102432460.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
i kappab kinase nf kappab signalingGO:0007249850.012
nucleotide catabolic processGO:00091662170.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
organic acid transportGO:00158491010.012
dephosphorylationGO:00163111290.012
cell activation involved in immune responseGO:00022631260.012
regulation of proteolysisGO:00301621640.012
regulation of neuron differentiationGO:00456642810.012
purine nucleoside metabolic processGO:00422782410.012
pigmentationGO:0043473710.012
positive regulation of cell activationGO:00508671580.012
nucleoside triphosphate metabolic processGO:00091412300.012
regulation of cell migrationGO:00303342190.012
positive regulation of b cell receptor signaling pathwayGO:005086140.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
synapse organizationGO:00508081250.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
positive regulation of programmed cell deathGO:00430682180.012
cell adhesionGO:00071553290.012
positive regulation of cytokine productionGO:00018191740.012
cellular calcium ion homeostasisGO:00068741190.012
negative regulation of protein modification processGO:00314001630.012
regulation of protein secretionGO:0050708820.012
regulation of protein transportGO:00512231630.012
regulation of hydrolase activityGO:00513362460.012
regulation of defense responseGO:00313472330.011
exocytosisGO:00068871210.011
peptide transportGO:00158331330.011
protein palmitoylationGO:0018345140.011
methylationGO:00322591340.011
lipid modificationGO:0030258650.011
response to radiationGO:00093141650.011
gland developmentGO:00487323300.011
negative regulation of phosphorus metabolic processGO:00105631840.011
plasma membrane organizationGO:0007009900.011
nucleoside catabolic processGO:00091642060.011
membrane lipid metabolic processGO:0006643530.011
lipoprotein metabolic processGO:0042157430.011
neuronal action potentialGO:0019228540.011
skeletal system developmentGO:00015013560.011
negative regulation of cell proliferationGO:00082852960.011
cellular response to molecule of bacterial originGO:0071219830.011
establishment or maintenance of cell polarityGO:0007163860.011
Worm
lymphocyte mediated immunityGO:00024491390.011
molting cycleGO:0042303900.011
membrane lipid biosynthetic processGO:0046467320.011
mitotic cell cycle processGO:19030471590.011
small gtpase mediated signal transductionGO:0007264970.011
lung developmentGO:00303241640.011
sensory perceptionGO:00076002450.011
organophosphate biosynthetic processGO:00904071220.011
purine ribonucleoside catabolic processGO:00461302050.011
tissue homeostasisGO:00018941150.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
negative regulation of protein phosphorylationGO:00019331260.011
mrna metabolic processGO:0016071840.011
response to molecule of bacterial originGO:00022371430.011
cell fate commitmentGO:00451652100.011
extracellular matrix organizationGO:00301981470.011
positive regulation of leukocyte differentiationGO:1902107860.011
toxin transportGO:1901998380.011
regulation of cell motilityGO:20001452360.011
chromatin modificationGO:00165681870.011
stem cell developmentGO:00488642190.011
digestive tract developmentGO:00485651900.011
positive regulation of proteolysisGO:0045862850.011
positive regulation of immune effector processGO:00026991070.011
sulfur compound metabolic processGO:00067901000.011
b cell activationGO:00421131610.011
protein polymerizationGO:0051258570.011
covalent chromatin modificationGO:00165691630.011
peptide secretionGO:00027901140.011
muscle cell differentiationGO:00426922610.011
lipid localizationGO:00108761260.011
positive regulation of organelle organizationGO:00106381280.011
positive regulation of protein transportGO:0051222930.010
multicellular organismal homeostasisGO:00488711640.010
germ cell developmentGO:00072811850.010
organelle assemblyGO:00709251770.010
cellular carbohydrate metabolic processGO:00442621190.010
myeloid cell differentiationGO:00300992330.010
small molecule catabolic processGO:0044282710.010
regulation of myeloid cell differentiationGO:0045637960.010
developmental maturationGO:00217001930.010
regulation of engulfment of apoptotic cellGO:190107420.010
histone modificationGO:00165701590.010
regulation of innate immune responseGO:0045088910.010
amide transportGO:00428861380.010
organelle fissionGO:00482851700.010
axon ensheathmentGO:0008366760.010
meiotic cell cycleGO:00513211220.010

Sptlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.018
Human
disease of anatomical entityDOID:700.018
Human
disease of cellular proliferationDOID:1456600.017
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.016
cancerDOID:16200.011
central nervous system diseaseDOID:33100.011
musculoskeletal system diseaseDOID:1700.010
neurodegenerative diseaseDOID:128900.010