Mus musculus

56 known processes

Nlrp5

NLR family, pyrin domain containing 5

(Aliases: Mater,Nalp5,PAN11,Op1)

Nlrp5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein complex assemblyGO:00436231160.251
modification dependent protein catabolic processGO:00199411330.240
fertilizationGO:00095661270.239
macromolecule catabolic processGO:00090572810.211
proteolysis involved in cellular protein catabolic processGO:00516031470.192
protein catabolic processGO:00301632210.189
negative regulation of protein metabolic processGO:00512482820.174
spermatogenesisGO:00072832840.133
ubiquitin dependent protein catabolic processGO:00065111290.128
modification dependent macromolecule catabolic processGO:00436321330.127
protein processingGO:00164851630.123
Mouse
regulation of cell cycleGO:00517262810.121
multi multicellular organism processGO:00447061090.120
cellular macromolecule catabolic processGO:00442652060.086
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.085
negative regulation of cell cycleGO:00457861230.084
regulation of cellular amine metabolic processGO:0033238200.080
cell adhesionGO:00071553290.080
regulation of protein maturationGO:1903317960.078
extracellular matrix organizationGO:00301981470.076
amine metabolic processGO:0009308450.075
negative regulation of nuclear divisionGO:0051784190.074
regulation of organelle organizationGO:00330432890.071
regulation of cellular catabolic processGO:00313292420.070
Mouse
negative regulation of protein maturationGO:1903318790.069
extracellular structure organizationGO:00430621480.065
negative regulation of cellular component organizationGO:00511291940.065
organonitrogen compound catabolic processGO:19015652640.063
nuclear divisionGO:00002801580.061
cation transportGO:00068123990.061
peptidyl amino acid modificationGO:00181933360.061
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.058
retina development in camera type eyeGO:00600411190.058
renal system developmentGO:00720012250.058
positive regulation of nervous system developmentGO:00519622210.057
negative regulation of protein processingGO:0010955790.057
cellular lipid metabolic processGO:00442553230.056
Mouse
regulation of protein processingGO:0070613960.053
regulation of cell cycle processGO:00105641600.053
regulation of mitotic cell cycleGO:00073461260.052
respiratory system developmentGO:00605411900.051
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.051
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.050
cellular ketone metabolic processGO:0042180840.049
cognitionGO:00508901490.049
cell divisionGO:00513011200.047
mitotic spindle checkpointGO:007117490.046
positive regulation of programmed cell deathGO:00430682180.046
Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.045
organelle assemblyGO:00709251770.045
lung developmentGO:00303241640.044
locomotory behaviorGO:00076261950.044
nucleoside metabolic processGO:00091162460.044
protein modification by small protein conjugationGO:00324461870.043
Mouse
regulation of mitotic cell cycle phase transitionGO:1901990730.043
negative regulation of cell cycle processGO:0010948690.043
regulation of secretion by cellGO:19035302490.043
Mouse
transmembrane transportGO:00550854120.042
negative regulation of proteolysisGO:0045861740.042
cellular protein catabolic processGO:00442571550.042
sensory perceptionGO:00076002450.041
cell cell recognitionGO:0009988440.041
regulation of cellular ketone metabolic processGO:0010565660.041
mitotic cell cycleGO:00002781950.041
regulation of system processGO:00440572000.040
male gamete generationGO:00482322850.040
positive regulation of protein modification processGO:00314012990.040
Mouse
establishment or maintenance of bipolar cell polarityGO:0061245210.040
regulation of proteasomal protein catabolic processGO:0061136460.040
negative regulation of cellular catabolic processGO:0031330470.039
learning or memoryGO:00076111480.039
establishment or maintenance of cell polarityGO:0007163860.039
protein ubiquitinationGO:00165671710.039
Mouse
cellular amino acid metabolic processGO:00065201030.038
binding of sperm to zona pellucidaGO:0007339340.038
protein modification by small protein conjugation or removalGO:00706472070.038
Mouse
small gtpase mediated signal transductionGO:0007264970.038
regulation of cellular component biogenesisGO:00440871810.037
single organismal cell cell adhesionGO:00163371310.036
positive regulation of apoptotic processGO:00430652170.036
Mouse
heterocycle catabolic processGO:00467002800.036
purine containing compound catabolic processGO:00725232130.036
carbohydrate derivative catabolic processGO:19011362310.035
positive regulation of neuron differentiationGO:00456661410.035
ribonucleotide catabolic processGO:00092612080.035
stem cell developmentGO:00488642190.035
regulation of neuron differentiationGO:00456642810.035
nucleobase containing small molecule metabolic processGO:00550863520.034
lymphocyte differentiationGO:00300982420.034
nucleoside triphosphate metabolic processGO:00091412300.034
oxidation reduction processGO:00551143420.034
Mouse
protein maturationGO:00516041760.034
Mouse
purine nucleoside metabolic processGO:00422782410.034
lipid biosynthetic processGO:00086101790.034
negative regulation of mitotic cell cycleGO:0045930580.034
respiratory tube developmentGO:00303231670.034
sperm egg recognitionGO:0035036370.034
regulation of chromosome segregationGO:0051983210.033
single organism cell adhesionGO:00986021560.033
cellular amine metabolic processGO:0044106440.033
regulation of hydrolase activityGO:00513362460.033
Mouse
connective tissue developmentGO:00614481790.032
mapk cascadeGO:00001652810.032
Mouse
regulation of cellular amino acid metabolic processGO:000652150.031
negative regulation of nik nf kappab signalingGO:190122320.031
Mouse
regulation of anatomical structure sizeGO:00900661780.031
leukocyte differentiationGO:00025213420.030
positive regulation of transferase activityGO:00513471670.030
Mouse
establishment or maintenance of apical basal cell polarityGO:0035088210.030
cell recognitionGO:0008037830.030
negative regulation of cell divisionGO:0051782240.030
camera type eye developmentGO:00430102660.030
positive regulation of cell deathGO:00109422240.030
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.030
glycosyl compound metabolic processGO:19016572460.030
lateral inhibitionGO:004633110.029
fat cell differentiationGO:00454441600.029
negative regulation of cellular protein catabolic processGO:1903363220.028
striated muscle tissue developmentGO:00147062930.028
purine nucleoside triphosphate catabolic processGO:00091462030.028
macromolecule methylationGO:00434141200.027
cellular response to growth factor stimulusGO:00713631970.027
purine nucleotide catabolic processGO:00061952110.027
chromosome separationGO:0051304140.027
circulatory system processGO:00030131970.027
purine ribonucleotide catabolic processGO:00091542080.027
transforming growth factor beta receptor signaling pathwayGO:0007179710.027
ribonucleoside triphosphate catabolic processGO:00092031990.027
regulation of transferase activityGO:00513382630.027
Mouse
metaphase anaphase transition of mitotic cell cycleGO:000709190.027
cellular response to transforming growth factor beta stimulusGO:0071560880.026
regulation of protein catabolic processGO:00421761080.026
dna methylationGO:0006306430.026
homeostasis of number of cellsGO:00488722100.026
purine containing compound metabolic processGO:00725213110.026
nucleoside phosphate catabolic processGO:19012922220.025
regulation of multi organism processGO:00439001110.025
Mouse
urogenital system developmentGO:00016552610.025
intracellular protein transportGO:00068862040.025
positive regulation of proteolysisGO:0045862850.025
Mouse
multicellular organism growthGO:00352641610.025
positive regulation of cell developmentGO:00107202370.025
ion transmembrane transportGO:00342203610.025
negative regulation of mitotic cell cycle phase transitionGO:1901991450.025
positive regulation of cellular catabolic processGO:00313311480.025
glycosyl compound catabolic processGO:19016582060.025
nucleoside catabolic processGO:00091642060.024
ossificationGO:00015032160.024
cell substrate adhesionGO:00315891300.024
purine nucleoside catabolic processGO:00061522050.024
purine nucleoside triphosphate metabolic processGO:00091442260.024
single fertilizationGO:0007338820.024
nucleoside triphosphate catabolic processGO:00091432050.024
response to growth factorGO:00708481980.024
organic hydroxy compound metabolic processGO:19016152030.024
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
proteasomal protein catabolic processGO:0010498980.024
regulation of hormone levelsGO:00108172110.024
positive regulation of protein phosphorylationGO:00019342420.023
Mouse
purine ribonucleoside catabolic processGO:00461302050.023
negative regulation of chromosome organizationGO:2001251300.023
cellular nitrogen compound catabolic processGO:00442702800.023
positive regulation of cellular amine metabolic processGO:003324050.023
organelle fissionGO:00482851700.023
regulation of ion transportGO:00432692150.023
meiotic nuclear divisionGO:00071261150.023
negative regulation of cellular amine metabolic processGO:003323910.023
rho protein signal transductionGO:0007266320.023
purine ribonucleoside metabolic processGO:00461282410.023
learningGO:0007612980.023
actin cytoskeleton organizationGO:00300362200.023
mitotic cell cycle processGO:19030471590.022
cellular response to cytokine stimulusGO:00713451890.022
Mouse
spermatid differentiationGO:00485151150.022
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.022
positive regulation of organelle organizationGO:00106381280.022
covalent chromatin modificationGO:00165691630.022
inorganic ion transmembrane transportGO:00986602340.022
regulation of mitotic sister chromatid segregationGO:0033047120.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
negative regulation of cellular amino acid metabolic processGO:004576300.022
regulation of mapk cascadeGO:00434082480.022
Mouse
chromosome segregationGO:0007059480.022
negative regulation of cellular protein metabolic processGO:00322692470.022
epithelial cell developmentGO:00020641590.022
response to transforming growth factor betaGO:0071559880.022
regulation of mitosisGO:0007088290.021
nephron epithelium developmentGO:0072009920.021
purine nucleotide metabolic processGO:00061633020.021
muscle system processGO:00030121410.021
reactive oxygen species metabolic processGO:0072593840.021
negative regulation of organelle organizationGO:0010639900.021
positive regulation of cell cycleGO:0045787920.021
regulation of cell divisionGO:0051302760.021
morphogenesis of a branching epitheliumGO:00611381930.021
regulation of establishment of protein localizationGO:00702011810.021
Mouse
organophosphate catabolic processGO:00464342320.021
regulation of proteolysisGO:00301621640.021
Mouse
regulation of cell cycle phase transitionGO:1901987770.021
leukocyte migrationGO:00509001240.021
Mouse
regulation of reproductive processGO:2000241660.021
bone developmentGO:00603481200.020
cell type specific apoptotic processGO:00972852680.020
Mouse
regulation of protein localizationGO:00328802310.020
Mouse
skeletal system developmentGO:00015013560.019
mitotic sister chromatid separationGO:005130690.019
blood circulationGO:00080151950.019
ovulation cycleGO:0042698590.019
regulation of cell adhesionGO:00301551540.019
myeloid cell homeostasisGO:00022621140.019
germ cell developmentGO:00072811850.019
response to radiationGO:00093141650.019
negative regulation of cell cycle phase transitionGO:1901988480.019
aromatic compound catabolic processGO:00194392860.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
nucleotide catabolic processGO:00091662170.019
carbohydrate metabolic processGO:00059752300.019
morphogenesis of embryonic epitheliumGO:00163311590.019
chromatin modificationGO:00165681870.019
positive regulation of hydrolase activityGO:00513451480.019
Mouse
interspecies interaction between organismsGO:0044419830.019
Mouse
embryonic organ morphogenesisGO:00485622760.018
negative regulation of intracellular signal transductionGO:19025321670.018
Mouse
branching morphogenesis of an epithelial tubeGO:00487541590.018
response to organonitrogen compoundGO:00102432460.018
Mouse
mitotic nuclear divisionGO:0007067480.018
kidney epithelium developmentGO:00720731210.018
peptide transportGO:00158331330.018
immune effector processGO:00022523210.018
Mouse
regulation of cell projection organizationGO:00313442060.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
response to molecule of bacterial originGO:00022371430.017
Mouse
development of primary sexual characteristicsGO:00451371430.017
regulation of secretionGO:00510462740.017
Mouse
cellular response to external stimulusGO:0071496880.017
negative regulation of phosphorus metabolic processGO:00105631840.017
Mouse
prevention of polyspermyGO:006046840.017
methylationGO:00322591340.017
gonad developmentGO:00084061410.017
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114590.017
nucleoside phosphate metabolic processGO:00067533380.017
ribose phosphate metabolic processGO:00196932910.017
gastrulationGO:00073691160.017
sister chromatid segregationGO:0000819200.017
purine ribonucleotide metabolic processGO:00091502900.017
protein localization to membraneGO:00726571080.017
mitochondrion organizationGO:00070051340.017
organic cyclic compound catabolic processGO:19013612950.017
epidermis developmentGO:00085441870.017
ribonucleoside metabolic processGO:00091192450.017
negative regulation of cell proliferationGO:00082852960.017
regulation of transmembrane transportGO:00347621280.017
regulation of leukocyte differentiationGO:19021051590.016
endothelial cell differentiationGO:0045446410.016
endomembrane system organizationGO:00102561470.016
blood vessel morphogenesisGO:00485142850.016
positive regulation of protein transportGO:0051222930.016
Mouse
skeletal system morphogenesisGO:00487052030.016
associative learningGO:0008306610.016
positive regulation of kinase activityGO:00336741550.016
Mouse
inorganic cation transmembrane transportGO:00986622070.016
negative regulation of multi organism processGO:0043901680.016
Mouse
response to organic cyclic compoundGO:00140701980.016
Mouse
ribonucleoside catabolic processGO:00424542060.016
chromatin organizationGO:00063252060.016
cellular homeostasisGO:00197252400.016
negative regulation of protein modification processGO:00314001630.016
cartilage developmentGO:00512161400.016
somite developmentGO:0061053810.016
stem cell differentiationGO:00488632680.016
cellular carbohydrate metabolic processGO:00442621190.015
cell matrix adhesionGO:0007160680.015
wnt signaling pathwayGO:00160551880.015
regulation of cellular response to growth factor stimulusGO:0090287820.015
response to lipopolysaccharideGO:00324961280.015
Mouse
cation transmembrane transportGO:00986552660.015
striated muscle cell developmentGO:00550021250.015
amino acid transmembrane transportGO:0003333370.015
regulation of cell motilityGO:20001452360.015
Mouse
kidney developmentGO:00018222130.015
nephron developmentGO:00720061090.015
negative regulation of protein catabolic processGO:0042177360.015
microtubule based processGO:00070172360.015
glial cell differentiationGO:00100011310.015
cellular chemical homeostasisGO:00550822150.015
negative regulation of phosphate metabolic processGO:00459361840.015
Mouse
palate developmentGO:0060021760.015
protein secretionGO:00093061110.015
Mouse
alcohol metabolic processGO:00060661160.015
embryonic skeletal system developmentGO:00487061200.015
formation of primary germ layerGO:0001704770.015
cell cycle checkpointGO:0000075470.014
positive regulation of nucleoside metabolic processGO:0045979910.014
divalent metal ion transportGO:00708381720.014
maintenance of locationGO:0051235890.014
cellular component assembly involved in morphogenesisGO:00109271390.014
muscle tissue developmentGO:00605373080.014
chemotaxisGO:00069352470.014
Mouse
regulation of intracellular transportGO:00323861590.014
response to light stimulusGO:00094161350.014
photoreceptor cell differentiationGO:0046530520.014
regulation of fat cell differentiationGO:0045598810.014
regulation of cytoskeleton organizationGO:00514931220.014
membrane organizationGO:00610242450.014
thymocyte migrationGO:007267920.014
mesodermal cell migrationGO:000807840.014
muscle cell differentiationGO:00426922610.014
paramesonephric duct developmentGO:006120530.014
actin filament polymerizationGO:0030041440.014
regulation of protein modification by small protein conjugation or removalGO:1903320570.014
Mouse
developmental maturationGO:00217001930.014
mesoderm developmentGO:00074981000.014
dna metabolic processGO:00062593030.014
regulation of nuclear divisionGO:0051783560.014
symbiosis encompassing mutualism through parasitismGO:0044403830.014
Mouse
response to nutrient levelsGO:00316671090.014
inner ear receptor cell differentiationGO:0060113610.014
androgen biosynthetic processGO:000670240.013
heart morphogenesisGO:00030071780.013
protein polymerizationGO:0051258570.013
limb morphogenesisGO:00351081490.013
skin developmentGO:00435882200.013
apoptotic signaling pathwayGO:00971903060.013
positive regulation of cellular component biogenesisGO:0044089940.013
male sex differentiationGO:00466611090.013
negative regulation of phosphorylationGO:00423261660.013
Mouse
regulation of chromosome organizationGO:0033044830.013
heart contractionGO:0060047930.013
pma inducible membrane protein ectodomain proteolysisGO:005108810.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.013
positive regulation of thymocyte migrationGO:200041220.013
regulation of lipid metabolic processGO:00192161180.013
Mouse
positive regulation of cell cycle processGO:0090068610.013
neuron deathGO:00709971540.013
Human
activation of mapk activity involved in innate immune responseGO:003541920.013
Mouse
regulation of cell migrationGO:00303342190.013
Mouse
neural precursor cell proliferationGO:00613511210.013
protein localization to nucleusGO:00345041210.013
regulation of intracellular protein transportGO:0033157820.013
positive regulation of cell projection organizationGO:0031346950.013
regulation of protein transportGO:00512231630.013
Mouse
regulation of cellular component sizeGO:00325351210.013
negative regulation of molecular functionGO:00440922580.013
Mouse
neuromuscular processGO:0050905990.013
negative regulation of secretion by cellGO:1903531540.013
endothelium developmentGO:0003158450.013
nitrogen compound transportGO:00717052710.013
ras protein signal transductionGO:0007265770.013
regulation of cellular response to stressGO:00801351590.012
Mouse
rhythmic processGO:00485111740.012
morphogenesis of a branching structureGO:00017632030.012
response to peptideGO:19016521360.012
Mouse
male meiosisGO:0007140370.012
lymphocyte mediated immunityGO:00024491390.012
Mouse
positive regulation of eosinophil migrationGO:200041820.012
regulation of cartilage developmentGO:0061035440.012
axonogenesisGO:00074092740.012
mesonephric epithelium developmentGO:0072163940.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
epithelium migrationGO:0090132630.012
regulation of ion transmembrane transportGO:00347651190.012
t cell activationGO:00421102890.012
hematopoietic progenitor cell differentiationGO:00022441430.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.012
calcium ion transportGO:00068161590.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
nucleocytoplasmic transportGO:00069131390.012
regulation of mitotic sister chromatid separationGO:0010965120.012
tissue homeostasisGO:00018941150.012
cytoplasmic transportGO:00164822340.012
nucleotide metabolic processGO:00091173320.012
mechanoreceptor differentiationGO:0042490670.012
bmp signaling pathwayGO:0030509930.012
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.012
cellular amide metabolic processGO:0043603580.012
Mouse
appendage morphogenesisGO:00351071490.012
cytokine productionGO:00018163190.012
Mouse
carbohydrate biosynthetic processGO:0016051740.012
regulation of thymocyte migrationGO:200041020.012
meiotic cell cycleGO:00513211220.012
negative regulation of cell developmentGO:00107211690.012
exocytosisGO:00068871210.012
retina morphogenesis in camera type eyeGO:0060042450.012
regulation of eosinophil migrationGO:200041620.012
nephron tubule developmentGO:0072080840.011
cellular response to dna damage stimulusGO:00069742070.011
embryonic limb morphogenesisGO:00303261260.011
ribonucleotide metabolic processGO:00092592910.011
positive regulation of protein catabolic processGO:0045732600.011
response to extracellular stimulusGO:00099911270.011
cellular response to nutrient levelsGO:0031669640.011
posttranscriptional regulation of gene expressionGO:00106081550.011
cellular metal ion homeostasisGO:00068751510.011
anatomical structure homeostasisGO:00602491450.011
regulation of actin cytoskeleton organizationGO:0032956840.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
organonitrogen compound biosynthetic processGO:19015661920.011
Mouse
positive regulation of cell migrationGO:00303351090.011
negative regulation of neuron apoptotic processGO:0043524920.011
protein localization to organelleGO:00333651850.011
mesenchymal cell differentiationGO:00487621070.011
regulation of blood pressureGO:0008217930.011
regulation of kinase activityGO:00435492490.011
Mouse
b cell differentiationGO:0030183780.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
multicellular organismal homeostasisGO:00488711640.011
protein targetingGO:00066051430.011
muscle cell developmentGO:00550011330.011
establishment of protein localization to organelleGO:00725941180.011
mitotic cell cycle checkpointGO:0007093310.011
regulation of muscle tissue developmentGO:1901861970.011
positive regulation of mitotic cell cycleGO:0045931410.011
somitogenesisGO:0001756690.011
compound eye developmentGO:004874910.011
regulation of protein serine threonine kinase activityGO:00719001570.011
Mouse
regulation of cellular protein catabolic processGO:1903362610.011
mesonephros developmentGO:0001823970.011
action potentialGO:0001508780.011
peptidyl lysine modificationGO:0018205770.011
cilium assemblyGO:0042384810.011
regulation of actin filament based processGO:0032970990.011
dna alkylationGO:0006305430.011
regulation of b cell tolerance inductionGO:000266120.011
glycoprotein metabolic processGO:00091001160.011
central nervous system neuron differentiationGO:00219531620.011
regulation of metaphase anaphase transition of cell cycleGO:190209990.011
positive regulation of viral genome replicationGO:004507020.011
sensory organ morphogenesisGO:00905962420.011
anion transmembrane transportGO:0098656710.011
cardiac muscle tissue developmentGO:00487381300.011
negative regulation of secretionGO:0051048610.011
atp metabolic processGO:0046034750.011
regulation of embryonic developmentGO:0045995710.011
dna modificationGO:0006304500.011
regulation of lymphocyte activationGO:00512492400.010
regulation of ras protein signal transductionGO:00465781140.010
regulation of muscle system processGO:0090257800.010
regulation of lymphocyte differentiationGO:00456191070.010
adult behaviorGO:00305341350.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
regulation of microtubule based processGO:0032886520.010
muscle contractionGO:00069361010.010
skeletal muscle organ developmentGO:00605381630.010
nucleoside monophosphate metabolic processGO:0009123850.010
positive regulation of cell motilityGO:20001471160.010
regulation of neuron apoptotic processGO:00435231220.010
positive regulation of cell adhesionGO:0045785800.010
regulation of endopeptidase activityGO:0052548890.010
Mouse
regulation of protein kinase activityGO:00458592320.010
Mouse
regionalizationGO:00030023370.010
nephron morphogenesisGO:0072028690.010
actin polymerization or depolymerizationGO:0008154540.010
lipid localizationGO:00108761260.010
developmental growth involved in morphogenesisGO:00605601380.010
rna interferenceGO:001624620.010
regulation of t cell activationGO:00508631700.010
nuclear transportGO:00511691390.010
epithelial cell morphogenesisGO:0003382410.010

Nlrp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
bone development diseaseDOID:008000600.018
connective tissue diseaseDOID:6500.018
bone diseaseDOID:008000100.018
musculoskeletal system diseaseDOID:1700.018
disease of metabolismDOID:001466700.013
nervous system diseaseDOID:86300.012