IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Rbbp4

retinoblastoma binding protein 4

(Aliases: mRbAp48)

Ensembl: ENSMUSG00000057236
Entrez: 19646
UniProtKB: Q60972

Process Predictions
Disease Predictions

Rbbp4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
histone methylation	GO:0016571	71	0.995	Fly
protein methylation	GO:0006479	81	0.993	Fly
dna metabolic process	GO:0006259	303	0.989	Yeast Fly
covalent chromatin modification	GO:0016569	163	0.981	Yeast Fly
histone h3 k9 methylation	GO:0051567	17	0.971
negative regulation of gene expression epigenetic	GO:0045814	15	0.970	Yeast Fly
chromatin modification	GO:0016568	187	0.968	Yeast Fly
histone modification	GO:0016570	159	0.966	Yeast Fly
histone lysine methylation	GO:0034968	50	0.954
chromatin organization	GO:0006325	206	0.920	Yeast Fly
regulation of chromosome organization	GO:0033044	83	0.833
methylation	GO:0032259	134	0.830	Fly
dna modification	GO:0006304	50	0.826
circadian rhythm	GO:0007623	114	0.812
regulation of histone methylation	GO:0031060	30	0.708
protein alkylation	GO:0008213	81	0.705	Fly
protein localization to chromatin	GO:0071168	3	0.699
negative regulation of chromosome organization	GO:2001251	30	0.699
chromatin assembly	GO:0031497	13	0.667	Yeast Fly
cellular response to dna damage stimulus	GO:0006974	207	0.626
negative regulation of cellular component organization	GO:0051129	194	0.586
macromolecule methylation	GO:0043414	120	0.583	Fly
rhythmic process	GO:0048511	174	0.552
positive regulation of histone h3 k27 methylation	GO:0061087	4	0.526
dna templated transcription termination	GO:0006353	4	0.524
spermatogenesis	GO:0007283	284	0.491
peptidyl lysine methylation	GO:0018022	29	0.479
chromatin silencing	GO:0006342	15	0.478	Yeast Fly
gene silencing by rna	GO:0031047	19	0.470	Worm
peptidyl lysine modification	GO:0018205	77	0.462	Yeast Fly
positive regulation of histone h3 k9 methylation	GO:0051574	4	0.451
regulation of chromatin modification	GO:1903308	57	0.436
rna interference	GO:0016246	2	0.401	Worm
negative regulation of histone methylation	GO:0031061	10	0.399
dna methylation	GO:0006306	43	0.374
spermatid development	GO:0007286	108	0.360
dna replication independent nucleosome assembly	GO:0006336	1	0.357
male gamete generation	GO:0048232	285	0.327
maintenance of cell number	GO:0098727	3	0.325
dna alkylation	GO:0006305	43	0.307
regulation of histone h3 k9 methylation	GO:0051570	8	0.307
genitalia development	GO:0048806	37	0.304	Worm
gene silencing	GO:0016458	38	0.301	Yeast Worm Fly
axon guidance	GO:0007411	141	0.294
positive regulation of chromatin modification	GO:1903310	28	0.276
regulation of circadian rhythm	GO:0042752	58	0.267
regulation of apoptotic signaling pathway	GO:2001233	197	0.264
nuclear division	GO:0000280	158	0.264
regulation of mrna splicing via spliceosome	GO:0048024	32	0.262
meiotic cell cycle	GO:0051321	122	0.262
regulation of organelle organization	GO:0033043	289	0.260
negative regulation of organelle organization	GO:0010639	90	0.243
negative regulation of striated muscle cell differentiation	GO:0051154	14	0.229
cell cycle comprising mitosis without cytokinesis	GO:0033301	1	0.204
dendrite development	GO:0016358	115	0.198	Fly
rna splicing	GO:0008380	54	0.193
protein modification by small protein conjugation or removal	GO:0070647	207	0.184
regulation of histone modification	GO:0031056	56	0.182
muscle cell differentiation	GO:0042692	261	0.177
posttranscriptional regulation of gene expression	GO:0010608	155	0.176	Worm
protein localization to organelle	GO:0033365	185	0.171
regulation of histone h3 k27 methylation	GO:0061085	6	0.164
germ line stem cell division	GO:0042078	2	0.164
regulation of striated muscle cell differentiation	GO:0051153	81	0.163
intracellular receptor signaling pathway	GO:0030522	74	0.163
gonad development	GO:0008406	141	0.161	Worm
positive regulation of organelle organization	GO:0010638	128	0.155
ras protein signal transduction	GO:0007265	77	0.151
stem cell differentiation	GO:0048863	268	0.149
exocrine pancreas development	GO:0031017	7	0.145
cellular response to oxidative stress	GO:0034599	76	0.144
actin cytoskeleton organization	GO:0030036	220	0.142
cell fate commitment	GO:0045165	210	0.142	Worm
protein ubiquitination	GO:0016567	171	0.139
apoptotic signaling pathway	GO:0097190	306	0.137
positive regulation of histone methylation	GO:0031062	16	0.136
histone h3 k27 methylation	GO:0070734	11	0.136
small gtpase mediated signal transduction	GO:0007264	97	0.131
mrna splicing via spliceosome	GO:0000398	43	0.131
skin development	GO:0043588	220	0.131
regulation of cell cycle	GO:0051726	281	0.130	Fly
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.129
posttranscriptional gene silencing	GO:0016441	10	0.127	Worm
microtubule based process	GO:0007017	236	0.125
stem cell maintenance	GO:0019827	130	0.125
segment specification	GO:0007379	15	0.124	Fly
multicellular organismal aging	GO:0010259	24	0.124
dna repair	GO:0006281	107	0.123
olfactory learning	GO:0008355	2	0.122
segmentation	GO:0035282	93	0.121	Fly
response to ionizing radiation	GO:0010212	42	0.117
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.117
response to oxidative stress	GO:0006979	123	0.116
translation	GO:0006412	93	0.111
development of primary sexual characteristics	GO:0045137	143	0.110	Worm
regulation of multi organism process	GO:0043900	111	0.110
viral process	GO:0016032	41	0.109
axonogenesis	GO:0007409	274	0.104
dna conformation change	GO:0071103	37	0.104	Yeast Fly
dna hypermethylation	GO:0044026	3	0.104
interspecies interaction between organisms	GO:0044419	83	0.103
meiotic cell cycle process	GO:1903046	77	0.102
response to lipopolysaccharide	GO:0032496	128	0.101
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.099
positive regulation of histone modification	GO:0031058	28	0.098
response to inorganic substance	GO:0010035	96	0.097
peptidyl amino acid modification	GO:0018193	336	0.097	Yeast Fly
histone ubiquitination	GO:0016574	10	0.096
germ cell development	GO:0007281	185	0.094
positive regulation of chromosome organization	GO:2001252	33	0.092
rna localization	GO:0006403	23	0.091
wound healing	GO:0042060	157	0.091	Zebrafish
dna packaging	GO:0006323	30	0.091	Yeast Fly
positive regulation of protein modification process	GO:0031401	299	0.090
regulation of cellular ketone metabolic process	GO:0010565	66	0.089
stem cell division	GO:0017145	30	0.089
body morphogenesis	GO:0010171	45	0.088
negative regulation of protein metabolic process	GO:0051248	282	0.088
negative regulation of dna templated transcription elongation	GO:0032785	6	0.084
female gamete generation	GO:0007292	74	0.083
nucleosome positioning	GO:0016584	4	0.083	Fly
nuclear transport	GO:0051169	139	0.081
regeneration	GO:0031099	38	0.081	Zebrafish
nucleosome assembly	GO:0006334	7	0.080	Yeast Fly
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.078
macromolecule deacylation	GO:0098732	37	0.078
hindbrain development	GO:0030902	128	0.076
spermatid differentiation	GO:0048515	115	0.075
metencephalon development	GO:0022037	89	0.074
epidermis development	GO:0008544	187	0.073
cellular amino acid metabolic process	GO:0006520	103	0.072
mrna transport	GO:0051028	13	0.072
termination of rna polymerase ii transcription	GO:0006369	1	0.071
viral life cycle	GO:0019058	36	0.071
organelle fission	GO:0048285	170	0.070
negative regulation of cellular protein metabolic process	GO:0032269	247	0.069
monocarboxylic acid biosynthetic process	GO:0072330	61	0.068
3 utr mediated mrna stabilization	GO:0070935	2	0.068
regulation of rna splicing	GO:0043484	37	0.067
regulation of mrna processing	GO:0050684	41	0.065
locomotory behavior	GO:0007626	195	0.065
regulation of protein stability	GO:0031647	52	0.064
mrna metabolic process	GO:0016071	84	0.062
protein localization to chromosome	GO:0034502	6	0.061
nucleoside triphosphate catabolic process	GO:0009143	205	0.060
cellular glucan metabolic process	GO:0006073	32	0.060
regulation of transferase activity	GO:0051338	263	0.060
oxidation reduction process	GO:0055114	342	0.059
negative regulation of epidermal cell differentiation	GO:0045605	7	0.059
mitotic cell cycle process	GO:1903047	159	0.059	Fly
regulation of mitotic cell cycle	GO:0007346	126	0.057	Fly
cytokinetic process	GO:0032506	2	0.057
positive regulation of cell development	GO:0010720	237	0.056
cell division	GO:0051301	120	0.056	Fly
chemotaxis	GO:0006935	247	0.056
response to organic cyclic compound	GO:0014070	198	0.056
neural tube development	GO:0021915	160	0.055
regulation of cellular amino acid metabolic process	GO:0006521	5	0.054
tissue regeneration	GO:0042246	22	0.052	Zebrafish
generation of precursor metabolites and energy	GO:0006091	103	0.049
stem cell development	GO:0048864	219	0.048
neuron projection guidance	GO:0097485	141	0.048
dna replication	GO:0006260	52	0.048
endocytosis	GO:0006897	168	0.048
regulation of cytoskeleton organization	GO:0051493	122	0.048
chromatin silencing at rdna	GO:0000183	3	0.047
intracellular protein transport	GO:0006886	204	0.047
protein deacetylation	GO:0006476	32	0.047
b cell activation	GO:0042113	161	0.046
regulation of chromatin organization	GO:1902275	57	0.046
posttranscriptional gene silencing by rna	GO:0035194	10	0.046	Worm
response to estrogen	GO:0043627	24	0.046
regulation of mapk cascade	GO:0043408	248	0.045
establishment or maintenance of cell polarity	GO:0007163	86	0.044
positive regulation of cellular amine metabolic process	GO:0033240	5	0.044
regulation of cellular component biogenesis	GO:0044087	181	0.044
regulation of cell growth	GO:0001558	91	0.043
modification dependent protein catabolic process	GO:0019941	133	0.043
oocyte axis specification	GO:0007309	2	0.043
digestive system development	GO:0055123	200	0.043	Worm
male sex differentiation	GO:0046661	109	0.042	Worm
negative regulation of chromatin modification	GO:1903309	19	0.042
negative regulation of transcription elongation from rna polymerase ii promoter	GO:0034244	6	0.042
carbohydrate metabolic process	GO:0005975	230	0.042
nucleocytoplasmic transport	GO:0006913	139	0.041
ossification	GO:0001503	216	0.041
histone h3 k9 dimethylation	GO:0036123	4	0.041
response to molecule of bacterial origin	GO:0002237	143	0.040
respiratory system development	GO:0060541	190	0.040
energy derivation by oxidation of organic compounds	GO:0015980	77	0.040
cell growth	GO:0016049	130	0.040
amine metabolic process	GO:0009308	45	0.040
negative regulation of protein modification process	GO:0031400	163	0.039
embryonic organ morphogenesis	GO:0048562	276	0.039	Worm
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.039
negative regulation of rna splicing	GO:0033119	12	0.039
cellular polysaccharide metabolic process	GO:0044264	38	0.038
determination of adult lifespan	GO:0008340	11	0.038
cellular amine metabolic process	GO:0044106	44	0.038
lung development	GO:0030324	164	0.037
camera type eye development	GO:0043010	266	0.037
muscle system process	GO:0003012	141	0.037
intracellular mrna localization	GO:0008298	4	0.037
sensory perception	GO:0007600	245	0.037
protein modification by small protein conjugation	GO:0032446	187	0.036
negative regulation of cell cycle process	GO:0010948	69	0.036
g1 s transition of mitotic cell cycle	GO:0000082	57	0.035
cytoplasmic transport	GO:0016482	234	0.035
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.035
positive regulation of histone h3 k4 methylation	GO:0051571	5	0.034
protein deacylation	GO:0035601	36	0.033
respiratory tube development	GO:0030323	167	0.033
chromosome segregation	GO:0007059	48	0.033
lateral inhibition	GO:0046331	1	0.032
regulation of cell cycle g1 s phase transition	GO:1902806	35	0.032
response to hydrogen peroxide	GO:0042542	32	0.032
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.032
negative regulation of multi organism process	GO:0043901	68	0.031
sensory organ morphogenesis	GO:0090596	242	0.031
histone monoubiquitination	GO:0010390	3	0.031
regulation of cell cycle phase transition	GO:1901987	77	0.031
cellular polysaccharide catabolic process	GO:0044247	5	0.030
regulation of histone h3 k4 methylation	GO:0051569	12	0.030
histone h2a ubiquitination	GO:0033522	3	0.030
developmental maturation	GO:0021700	193	0.030
response to reactive oxygen species	GO:0000302	56	0.030
cellular carbohydrate metabolic process	GO:0044262	119	0.030
digestive tract morphogenesis	GO:0048546	147	0.030	Worm
embryonic digestive tract development	GO:0048566	27	0.030	Worm
regulation of ras protein signal transduction	GO:0046578	114	0.029
cellular homeostasis	GO:0019725	240	0.029
positive regulation of mapk cascade	GO:0043410	170	0.029
gliogenesis	GO:0042063	141	0.028
regulation of glycogen catabolic process	GO:0005981	2	0.028
protein polyubiquitination	GO:0000209	33	0.028
internal protein amino acid acetylation	GO:0006475	42	0.028	Yeast Fly
regulation of cell division	GO:0051302	76	0.028
positive regulation of transferase activity	GO:0051347	167	0.028
cellular response to organonitrogen compound	GO:0071417	145	0.028
cellular protein complex assembly	GO:0043623	116	0.028
negative regulation of phagocytosis	GO:0050765	4	0.028
oocyte construction	GO:0007308	2	0.028
cellularization	GO:0007349	1	0.027
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.027
regulation of hormone levels	GO:0010817	211	0.027
phagocytosis	GO:0006909	66	0.027
negative regulation of cell projection organization	GO:0031345	56	0.027
neural tube patterning	GO:0021532	43	0.027
cellular response to acid chemical	GO:0071229	68	0.026
liver development	GO:0001889	66	0.026
response to steroid hormone	GO:0048545	56	0.026
myosin filament assembly	GO:0031034	2	0.026
cellular ketone metabolic process	GO:0042180	84	0.026
rna splicing via transesterification reactions	GO:0000375	43	0.026
regulation of cell cycle process	GO:0010564	160	0.025
organic acid biosynthetic process	GO:0016053	86	0.025
positive regulation of growth	GO:0045927	104	0.025
lymphocyte differentiation	GO:0030098	242	0.025
regulation of cellular catabolic process	GO:0031329	242	0.025
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.025
microtubule cytoskeleton organization	GO:0000226	157	0.025
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.025
defense response to other organism	GO:0098542	197	0.025
histone h3 deacetylation	GO:0070932	8	0.025
rostrocaudal neural tube patterning	GO:0021903	12	0.025
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.025
response to heat	GO:0009408	27	0.025
regulation of gliogenesis	GO:0014013	50	0.024
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.024
modification dependent macromolecule catabolic process	GO:0043632	133	0.024
regulation of cellular amine metabolic process	GO:0033238	20	0.024
forebrain development	GO:0030900	302	0.024
histone h2a monoubiquitination	GO:0035518	1	0.024
multi multicellular organism process	GO:0044706	109	0.024
rna transport	GO:0050658	18	0.024
glycogen metabolic process	GO:0005977	32	0.024
nitrogen compound transport	GO:0071705	271	0.023
response to acid chemical	GO:0001101	111	0.023
nucleobase containing compound transport	GO:0015931	27	0.023
cardiac muscle cell differentiation	GO:0055007	69	0.023
protein catabolic process	GO:0030163	221	0.023
response to radiation	GO:0009314	165	0.022
dna methylation involved in gamete generation	GO:0043046	15	0.022
gland development	GO:0048732	330	0.022
circulatory system process	GO:0003013	197	0.022
fatty acid metabolic process	GO:0006631	121	0.022
cellular response to lipid	GO:0071396	145	0.022
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.022
reproductive behavior	GO:0019098	32	0.022
nucleoside phosphate metabolic process	GO:0006753	338	0.022
histone acetylation	GO:0016573	41	0.022	Yeast Fly
skeletal system development	GO:0001501	356	0.022
smoothened signaling pathway	GO:0007224	105	0.021
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.021
circadian regulation of gene expression	GO:0032922	48	0.021
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.021
regulation of translation	GO:0006417	71	0.021
telencephalon development	GO:0021537	186	0.021
cerebellum development	GO:0021549	77	0.021
negative regulation of viral process	GO:0048525	23	0.021
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.021
digestive tract development	GO:0048565	190	0.021	Worm
negative regulation of cell proliferation	GO:0008285	296	0.020
fatty acid biosynthetic process	GO:0006633	41	0.020
engulfment of apoptotic cell	GO:0043652	3	0.020
pallium development	GO:0021543	120	0.020
positive regulation of nervous system development	GO:0051962	221	0.020
compound eye development	GO:0048749	1	0.020
sperm individualization	GO:0007291	1	0.020
organic cyclic compound catabolic process	GO:1901361	295	0.020
positive regulation of cellular catabolic process	GO:0031331	148	0.020
cell junction organization	GO:0034330	77	0.020
neuron migration	GO:0001764	122	0.020
nucleotide catabolic process	GO:0009166	217	0.020
mapk cascade	GO:0000165	281	0.020
cognition	GO:0050890	149	0.019
mrna processing	GO:0006397	63	0.019
regulation of sarcomere organization	GO:0060297	4	0.019
hepaticobiliary system development	GO:0061008	67	0.019
gene silencing by mirna	GO:0035195	10	0.019
regulation of neuron differentiation	GO:0045664	281	0.019
erythrocyte differentiation	GO:0030218	88	0.019
meiotic nuclear division	GO:0007126	115	0.019
mitotic cell cycle embryonic	GO:0045448	5	0.019
carbohydrate biosynthetic process	GO:0016051	74	0.019
organelle assembly	GO:0070925	177	0.019
intrinsic apoptotic signaling pathway	GO:0097193	132	0.019
dna dependent dna replication	GO:0006261	24	0.019
ribose phosphate metabolic process	GO:0019693	291	0.018
regulation of retinoic acid receptor signaling pathway	GO:0048385	7	0.018
regulation of mrna metabolic process	GO:1903311	43	0.018
negative regulation of cell cycle phase transition	GO:1901988	48	0.018
oogenesis	GO:0048477	56	0.018
protein depolymerization	GO:0051261	34	0.018
regulation of receptor biosynthetic process	GO:0010869	2	0.018
mitotic cell cycle	GO:0000278	195	0.018	Fly
negative regulation of b cell differentiation	GO:0045578	4	0.018
polysaccharide metabolic process	GO:0005976	39	0.018
spindle assembly involved in mitosis	GO:0090307	4	0.018
protein acylation	GO:0043543	64	0.018	Yeast Fly
protein dna complex subunit organization	GO:0071824	28	0.018	Yeast Fly
lipid biosynthetic process	GO:0008610	179	0.018
dna dependent dna replication maintenance of fidelity	GO:0045005	3	0.018
negative regulation of phosphorylation	GO:0042326	166	0.018
regulation of lymphocyte activation	GO:0051249	240	0.018
response to temperature stimulus	GO:0009266	55	0.018
regulation of neural precursor cell proliferation	GO:2000177	70	0.017
positive regulation of programmed cell death	GO:0043068	218	0.017
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.017
multicellular organism growth	GO:0035264	161	0.017
cardiac muscle cell development	GO:0055013	39	0.017
oocyte anterior posterior axis specification	GO:0007314	2	0.017
cellular response to hormone stimulus	GO:0032870	150	0.017
negative regulation of ras protein signal transduction	GO:0046580	18	0.017
negative regulation of mitotic cell cycle	GO:0045930	58	0.017
regulation of protein maturation	GO:1903317	96	0.017
internal peptidyl lysine acetylation	GO:0018393	42	0.017	Yeast Fly
cell fate specification	GO:0001708	72	0.017	Worm
positive regulation of cell growth	GO:0030307	33	0.017
retina development in camera type eye	GO:0060041	119	0.017
regulation of dna methylation	GO:0044030	12	0.016
cell type specific apoptotic process	GO:0097285	268	0.016
cellular protein catabolic process	GO:0044257	155	0.016
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.016
mitotic cytokinesis	GO:0000281	4	0.016	Fly
myeloid cell differentiation	GO:0030099	233	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.016
viral gene expression	GO:0019080	3	0.016
histone deacetylation	GO:0016575	26	0.016
extrinsic apoptotic signaling pathway	GO:0097191	126	0.016
dna templated transcription elongation	GO:0006354	13	0.016
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.016
mechanosensory behavior	GO:0007638	6	0.016
aromatic compound catabolic process	GO:0019439	286	0.016
histone h3 k36 demethylation	GO:0070544	2	0.016
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.016
organophosphate catabolic process	GO:0046434	232	0.016
double strand break repair	GO:0006302	48	0.016
adult behavior	GO:0030534	135	0.016
endomembrane system organization	GO:0010256	147	0.016
regulation of actin cytoskeleton organization	GO:0032956	84	0.015
membrane organization	GO:0061024	245	0.015
nucleoside metabolic process	GO:0009116	246	0.015
nucleic acid transport	GO:0050657	18	0.015
energy reserve metabolic process	GO:0006112	39	0.015
homeostasis of number of cells	GO:0048872	210	0.015
ribonucleotide metabolic process	GO:0009259	291	0.015
regulation of cell activation	GO:0050865	289	0.015
cellular chemical homeostasis	GO:0055082	215	0.015
regulation of endocytosis	GO:0030100	69	0.015
regulation of cellular response to stress	GO:0080135	159	0.015
regulation of carbohydrate metabolic process	GO:0006109	75	0.015
nucleotide excision repair	GO:0006289	13	0.015
regulation of b cell activation	GO:0050864	81	0.015
regulation of generation of precursor metabolites and energy	GO:0043467	38	0.015
glycosylation	GO:0070085	62	0.015
mitotic nuclear division	GO:0007067	48	0.014
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.014
carboxylic acid biosynthetic process	GO:0046394	86	0.014
purine ribonucleoside catabolic process	GO:0046130	205	0.014
glucan metabolic process	GO:0044042	32	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	34	0.014
carbohydrate derivative biosynthetic process	GO:1901137	183	0.014
regulation of synapse structural plasticity	GO:0051823	4	0.014
canonical wnt signaling pathway	GO:0060070	130	0.014
hematopoietic progenitor cell differentiation	GO:0002244	143	0.014
mrna stabilization	GO:0048255	9	0.014
neural tube closure	GO:0001843	90	0.014
wnt signaling pathway	GO:0016055	188	0.014
regulation of nucleoside metabolic process	GO:0009118	130	0.014
purine ribonucleotide catabolic process	GO:0009154	208	0.014
protein processing	GO:0016485	163	0.014
regulation of mrna stability	GO:0043488	23	0.014
cellular component assembly involved in morphogenesis	GO:0010927	139	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.013
developmental growth involved in morphogenesis	GO:0060560	138	0.013
cellular response to cytokine stimulus	GO:0071345	189	0.013
negative regulation of intracellular signal transduction	GO:1902532	167	0.013
establishment of rna localization	GO:0051236	18	0.013
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.013
purine nucleotide catabolic process	GO:0006195	211	0.013
positive regulation of ubiquitin protein transferase activity	GO:0051443	4	0.013
cellular response to steroid hormone stimulus	GO:0071383	33	0.013
protein maturation	GO:0051604	176	0.013
negative regulation of cell division	GO:0051782	24	0.013
cardiac cell development	GO:0055006	41	0.013
learning	GO:0007612	98	0.013
cerebellar cortex development	GO:0021695	48	0.013
regulation of peptidase activity	GO:0052547	96	0.013
nucleus organization	GO:0006997	45	0.013
negative regulation of muscle cell differentiation	GO:0051148	33	0.013
regulation of system process	GO:0044057	200	0.013
purine nucleoside catabolic process	GO:0006152	205	0.013
positive regulation of protein phosphorylation	GO:0001934	242	0.013
negative regulation of proteolysis	GO:0045861	74	0.013
pole plasm assembly	GO:0007315	2	0.013
regulation of g1 s transition of mitotic cell cycle	GO:2000045	35	0.013
histone h3 k27 demethylation	GO:0071557	4	0.013
regulation of proteasomal protein catabolic process	GO:0061136	46	0.013
nucleotide metabolic process	GO:0009117	332	0.012
regulation of nucleotide metabolic process	GO:0006140	169	0.012
purine containing compound catabolic process	GO:0072523	213	0.012
response to amine	GO:0014075	16	0.012
monocarboxylic acid metabolic process	GO:0032787	191	0.012
macromolecule catabolic process	GO:0009057	281	0.012
striated muscle cell development	GO:0055002	125	0.012
nucleoside monophosphate metabolic process	GO:0009123	85	0.012
viral genome replication	GO:0019079	17	0.012
nuclear export	GO:0051168	34	0.012
regulation of vesicle mediated transport	GO:0060627	139	0.012
negative regulation of cell cycle	GO:0045786	123	0.012
negative regulation of growth	GO:0045926	99	0.012
alpha amino acid metabolic process	GO:1901605	59	0.012
response to oxygen levels	GO:0070482	62	0.012
regulation of gene expression by genetic imprinting	GO:0006349	15	0.012
regulation of actin filament based process	GO:0032970	99	0.012
maintenance of protein location in nucleus	GO:0051457	2	0.012
negative regulation of histone h3 k9 methylation	GO:0051573	4	0.012
cellular protein complex disassembly	GO:0043624	36	0.012
ncrna 3 end processing	GO:0043628	2	0.012
positive regulation of cell cycle	GO:0045787	92	0.012
pharynx development	GO:0060465	1	0.012
histone h3 k4 methylation	GO:0051568	23	0.012
small molecule biosynthetic process	GO:0044283	132	0.012
macromolecular complex disassembly	GO:0032984	43	0.012
regulation of smoothened signaling pathway	GO:0008589	58	0.012
monosaccharide metabolic process	GO:0005996	106	0.012
nucleoside monophosphate catabolic process	GO:0009125	59	0.012
adult locomotory behavior	GO:0008344	91	0.012
purine containing compound metabolic process	GO:0072521	311	0.012
ribonucleoside metabolic process	GO:0009119	245	0.012
neural precursor cell proliferation	GO:0061351	121	0.012
multi organism behavior	GO:0051705	62	0.012
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.011
viral transcription	GO:0019083	3	0.011
snrna 3 end processing	GO:0034472	1	0.011
transcription elongation from rna polymerase ii promoter	GO:0006368	9	0.011
positive regulation of dna templated transcription elongation	GO:0032786	2	0.011
cellular lipid metabolic process	GO:0044255	323	0.011
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
organ growth	GO:0035265	117	0.011
cell adhesion	GO:0007155	329	0.011
proteasomal protein catabolic process	GO:0010498	98	0.011
bone development	GO:0060348	120	0.011
nuclear import	GO:0051170	95	0.011
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.011
cell substrate junction assembly	GO:0007044	24	0.011
regulation of neuron projection development	GO:0010975	169	0.011
regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO:1902041	22	0.011
mrna 3 end processing	GO:0031124	16	0.011
regulation of lymphocyte differentiation	GO:0045619	107	0.011
protein targeting	GO:0006605	143	0.011

Rbbp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.154
nervous system disease	DOID:863	0.154
central nervous system disease	DOID:331	0.026
neurodegenerative disease	DOID:1289	0.022
physical disorder	DOID:0080015	0.015
motor neuron disease	DOID:231	0.013

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