Mus musculus

472 known processes

Smo

smoothened homolog (Drosophila)

(Aliases: bnb,E130215L21Rik,Smoh,smoothened)

Smo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nodal signaling pathway involved in determination of left right asymmetryGO:003810721.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016421.000
neural crest cell migration involved in autonomic nervous system developmentGO:190116651.000
neural tube closureGO:0001843901.000
regionalizationGO:00030023371.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009421.000
auditory receptor cell fate determinationGO:004266831.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007203941.000
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135021.000
anterior commissure morphogenesisGO:002196061.000
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187421.000
embryonic organ morphogenesisGO:00485622761.000
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.999
embryonic limb morphogenesisGO:00303261260.999
negative regulation of gastrulationGO:200054230.999
midbrain hindbrain boundary morphogenesisGO:002155540.999
pyramidal neuron migrationGO:002185210.999
positive regulation of branching involved in ureteric bud morphogenesisGO:0090190180.999
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.999
axial mesodermal cell fate commitmentGO:004832210.998
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.998
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.998
formation of radial glial scaffoldsGO:002194340.998
embryonic skeletal system morphogenesisGO:0048704910.998
Zebrafish
neural tube formationGO:00018411080.997
hindbrain tangential cell migrationGO:002193420.997
trachea formationGO:006044030.997
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.997
stem cell differentiationGO:00488632680.997
nephron tubule morphogenesisGO:0072078680.997
primary neural tube formationGO:0014020950.997
axis elongation involved in somitogenesisGO:009024540.997
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.996
mesenchymal cell apoptotic process involved in nephron morphogenesisGO:190114540.996
positive regulation of auditory receptor cell differentiationGO:004560910.996
cell proliferation involved in outflow tract morphogenesisGO:006132540.995
cardiac right atrium morphogenesisGO:000321330.995
mitral valve developmentGO:000317440.995
regulation of endodermal cell fate specificationGO:004266320.995
appendage morphogenesisGO:00351071490.995
Zebrafish
neuron projection guidanceGO:00974851410.995
Zebrafish Rat
regulation of wnt signaling pathwayGO:00301111230.995
skeletal system developmentGO:00015013560.995
Zebrafish
cell proliferation in hindbrainGO:0021534100.994
limb morphogenesisGO:00351081490.994
hindbrain developmentGO:00309021280.994
embryonic heart tube formationGO:000314410.994
telencephalon developmentGO:00215371860.994
locus ceruleus developmentGO:002170310.993
lung inductionGO:006049230.993
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007204040.993
regulation of astrocyte differentiationGO:0048710200.993
embryonic skeletal joint morphogenesisGO:0060272110.993
regulation of endodermal cell differentiationGO:190322420.993
renal vesicle inductionGO:007203430.992
floor plate morphogenesisGO:003350530.992
Zebrafish
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.992
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationGO:002193840.992
closure of optic fissureGO:006138620.991
regulation of transcription involved in primary germ layer cell fate commitmentGO:006079620.991
hypophysis morphogenesisGO:004885030.991
positive regulation of inner ear receptor cell differentiationGO:200098210.991
neural tube patterningGO:0021532430.991
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076310.990
thyroid stimulating hormone secreting cell differentiationGO:006012940.990
embryonic viscerocranium morphogenesisGO:004870380.990
Zebrafish
negative regulation of endodermal cell differentiationGO:190322510.989
endodermal cell fate commitmentGO:0001711120.989
cardiac atrium morphogenesisGO:0003209230.988
branching involved in ureteric bud morphogenesisGO:0001658560.988
midbrain hindbrain boundary developmentGO:003091790.988
heart field specificationGO:000312860.988
negative regulation of chondrocyte differentiationGO:0032331130.988
appendage developmentGO:00487361660.986
Zebrafish
trachea cartilage morphogenesisGO:006053540.985
embryonic nail plate morphogenesisGO:003588030.985
limb developmentGO:00601731660.984
ventricular zone neuroblast divisionGO:002184730.984
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.984
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.984
midbrain hindbrain boundary maturationGO:002173210.983
epithelial tube formationGO:00721751300.981
Zebrafish
negative regulation of endodermal cell fate specificationGO:004266410.981
tube closureGO:0060606910.981
olfactory bulb interneuron developmentGO:002189170.979
mesenchymal cell developmentGO:0014031930.978
metanephric capsule specificationGO:007226710.978
forebrain regionalizationGO:0021871250.976
Zebrafish
endodermal cell fate specificationGO:000171440.976
cerebellum developmentGO:0021549770.976
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.975
negative regulation of planar cell polarity pathway involved in heart morphogenesisGO:200016010.975
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.975
mesenchyme developmentGO:00604851520.975
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.974
kidney morphogenesisGO:0060993830.974
hindlimb morphogenesisGO:0035137420.974
negative regulation of bmp signaling pathwayGO:0030514350.973
osteoblast developmentGO:0002076170.972
regulation of smoothened signaling pathwayGO:0008589580.972
gastrulationGO:00073691160.972
epithelial tube morphogenesisGO:00605623030.972
negative regulation of photoreceptor cell differentiationGO:004653340.971
stem cell developmentGO:00488642190.971
roof plate formationGO:002150910.970
bmp signaling pathway involved in heart developmentGO:006131220.970
apoptotic process involved in outflow tract morphogenesisGO:000327520.970
trophectodermal cellular morphogenesisGO:000183130.969
neural tube developmentGO:00219151600.969
pituitary gland developmentGO:0021983380.967
Zebrafish
morphogenesis of embryonic epitheliumGO:00163311590.967
Zebrafish
somitogenesisGO:0001756690.966
negative regulation of astrocyte differentiationGO:0048712100.965
rostrocaudal neural tube patterningGO:0021903120.965
mesenchymal cell proliferation involved in ureteric bud developmentGO:007213830.965
forebrain neuron differentiationGO:0021879520.964
central nervous system neuron differentiationGO:00219531620.964
forebrain generation of neuronsGO:0021872630.964
metanephric nephron tubule formationGO:007228940.964
embryonic heart tube anterior posterior pattern specificationGO:003505430.964
endocardial cell differentiationGO:006095640.964
Zebrafish
ear developmentGO:00435832000.962
Zebrafish
negative regulation of cell fate specificationGO:000999640.962
neural crest formationGO:001402920.962
negative regulation of prostatic bud formationGO:006068640.962
rhombomere morphogenesisGO:002159320.961
left lung morphogenesisGO:006046030.961
respiratory system developmentGO:00605411900.960
negative regulation of neuron differentiationGO:00456651010.959
regulation of intracellular transportGO:00323861590.959
wnt signaling pathway planar cell polarity pathwayGO:0060071270.959
ossificationGO:00015032160.959
inner ear receptor cell differentiationGO:0060113610.959
chondrocyte differentiationGO:0002062720.957
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.956
regulation of bmp signaling pathwayGO:0030510600.956
neural crest cell fate commitmentGO:001403410.955
regulation of cell proliferation involved in heart morphogenesisGO:2000136150.954
cell proliferation in midbrainGO:003327820.954
neuroblast differentiationGO:001401620.953
forebrain radial glial cell differentiationGO:002186140.952
diencephalon morphogenesisGO:004885260.950
central nervous system neuron developmentGO:0021954670.949
ascending aorta morphogenesisGO:003591030.949
olfactory lobe developmentGO:0021988320.948
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.947
septum primum developmentGO:000328440.946
otic placode formationGO:004304910.946
smoothened signaling pathwayGO:00072241050.945
planar cell polarity pathway involved in outflow tract morphogenesisGO:006134720.944
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.944
tube formationGO:00351481400.944
Zebrafish
non canonical wnt signaling pathway involved in heart developmentGO:006134130.942
central nervous system projection neuron axonogenesisGO:0021952210.942
tendon formationGO:003599240.941
wnt signaling pathway involved in somitogenesisGO:009024440.940
forebrain anterior posterior pattern specificationGO:002179750.938
axon guidanceGO:00074111410.938
Zebrafish Rat
midbrain hindbrain boundary maturation during brain developmentGO:002200410.937
stem cell proliferationGO:00720891170.937
positive regulation of transcription by glucoseGO:004601630.937
endochondral bone morphogenesisGO:0060350500.937
regulation of wnt signaling pathway planar cell polarity pathwayGO:2000095100.936
positive regulation of tendon cell differentiationGO:200105110.936
axial mesoderm formationGO:004832030.935
negative regulation of cartilage developmentGO:0061037170.934
chondrocyte developmentGO:0002063240.934
cardiac endothelial cell differentiationGO:000334840.934
Zebrafish
positive regulation of branching involved in lung morphogenesisGO:006104740.934
nephrogenic mesenchyme morphogenesisGO:007213420.934
peripheral nervous system neuron axonogenesisGO:004893630.932
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.932
cardiac septum developmentGO:0003279590.931
embryonic skeletal system developmentGO:00487061200.929
Zebrafish
central nervous system vasculogenesisGO:002200930.928
oligodendrocyte differentiationGO:0048709530.928
Zebrafish
ureter morphogenesisGO:007219740.926
embryonic epithelial tube formationGO:00018381300.924
positive regulation of glial cell differentiationGO:0045687210.924
nucleus accumbens developmentGO:002176810.923
central nervous system morphogenesisGO:002155120.922
negative regulation of glial cell proliferationGO:006025340.921
camera type eye developmentGO:00430102660.921
Zebrafish
planar cell polarity pathway involved in ventricular septum morphogenesisGO:006134820.920
regulation of myoblast differentiationGO:0045661290.920
spinal cord association neuron differentiationGO:0021527140.917
axial mesodermal cell fate specificationGO:004832710.910
negative regulation of apoptotic process involved in outflow tract morphogenesisGO:190225720.909
negative regulation of cell developmentGO:00107211690.908
regulation of apoptotic process involved in outflow tract morphogenesisGO:190225620.907
forebrain neuron developmentGO:0021884300.907
regulation of chondrocyte differentiationGO:0032330330.907
forebrain neuroblast divisionGO:002187390.906
oculomotor nerve morphogenesisGO:002162220.905
regulation of planar cell polarity pathway involved in neural tube closureGO:200016710.905
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitmentGO:002188230.903
ear morphogenesisGO:00424711180.901
Zebrafish
smoothened signaling pathway involved in ventral spinal cord patterningGO:002191070.901
establishment of planar polarity involved in neural tube closureGO:0090177150.901
regulation of muscle tissue developmentGO:1901861970.900
smoothened signaling pathway involved in dorsal ventral neural tube patterningGO:0060831120.899
glomerular mesangial cell developmentGO:007214430.898
noradrenergic neuron differentiationGO:000335760.898
embryonic appendage morphogenesisGO:00351131260.897
growth plate cartilage developmentGO:0003417140.896
negative regulation of osteoblast differentiationGO:0045668300.896
embryonic heart tube left right pattern formationGO:006097150.895
astrocyte differentiationGO:0048708430.894
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014910.894
embryonic heart tube morphogenesisGO:0003143510.893
inner cell mass cellular morphogenesisGO:000182810.893
formation of primary germ layerGO:0001704770.892
cardiac atrium developmentGO:0003230240.892
positive regulation of secondary heart field cardioblast proliferationGO:007251340.887
olfactory bulb interneuron differentiationGO:0021889120.887
negative regulation of mesodermal cell fate specificationGO:004266230.886
embryonic heart tube developmentGO:0035050650.886
embryonic skeletal joint developmentGO:0072498130.885
globus pallidus developmentGO:002175920.882
planar cell polarity pathway involved in heart morphogenesisGO:006134630.882
nephric duct formationGO:007217940.881
regulation of skeletal muscle fiber developmentGO:0048742360.880
regulation of establishment of planar polarity involved in neural tube closureGO:0090178150.877
astrocyte fate commitmentGO:006001840.876
branch elongation involved in ureteric bud branchingGO:006068130.873
hindbrain formationGO:002157610.873
negative regulation of branching involved in ureteric bud morphogenesisGO:009019140.872
positive regulation of skeletal muscle tissue regenerationGO:004341540.871
retinal ganglion cell axon guidanceGO:0031290180.870
Zebrafish
growth plate cartilage chondrocyte developmentGO:000343130.870
cartilage morphogenesisGO:0060536110.870
cerebellum formationGO:002158810.869
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathwayGO:003579310.868
mitral valve morphogenesisGO:000318340.868
stem cell maintenanceGO:00198271300.866
cerebellar granule cell precursor proliferationGO:0021930100.864
cranial suture morphogenesisGO:006036380.860
orbitofrontal cortex developmentGO:002176920.860
rhombomere 3 morphogenesisGO:002165820.858
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016210.858
regulation of gliogenesisGO:0014013500.857
negative regulation of cardiac chamber morphogenesisGO:190122020.857
cardiac right ventricle formationGO:000321930.856
cerebral cortex gabaergic interneuron fate commitmentGO:002189320.856
bone mineralizationGO:0030282540.855
negative regulation of glial cell differentiationGO:0045686210.854
primary prostatic bud elongationGO:006051620.853
axial mesodermal cell differentiationGO:004832110.851
cardiogenic plate morphogenesisGO:000314210.851
subpallium developmentGO:0021544200.851
growth plate cartilage chondrocyte growthGO:000343020.850
positive regulation of wnt signaling pathwayGO:0030177450.849
bmp signaling pathwayGO:0030509930.849
mesonephric duct morphogenesisGO:007218040.848
rhombomere 2 developmentGO:002156820.847
cell proliferation in forebrainGO:0021846300.839
oligodendrocyte developmentGO:0014003200.839
Zebrafish
apoptotic process involved in patterning of blood vesselsGO:190226260.836
tangential migration from the subventricular zone to the olfactory bulbGO:002202850.835
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.835
mammary placode formationGO:006059640.835
sinoatrial node cell differentiationGO:006092130.833
cardiocyte differentiationGO:0035051870.830
Zebrafish
determination of heart left right asymmetryGO:0061371480.829
regulation of canonical wnt signaling pathwayGO:0060828820.828
male sex differentiationGO:00466611090.826
cardiac septum morphogenesisGO:0060411460.826
regulation of planar cell polarity pathway involved in heart morphogenesisGO:200015910.825
mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333790.825
autonomic nervous system developmentGO:0048483430.823
Rat
spinal cord dorsal ventral patterningGO:0021513230.820
mesonephric tubule developmentGO:0072164940.820
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016410.819
negative regulation of stem cell maintenanceGO:190245540.816
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferationGO:006132420.814
positive regulation of transcription via serum response element bindingGO:001073510.812
substrate dependent cerebral cortex tangential migrationGO:002182530.811
cerebral cortex radial glia guided migrationGO:0021801170.808
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.808
negative regulation of planar cell polarity pathway involved in neural tube closureGO:200016810.807
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationGO:002193760.803
left lung developmentGO:006045940.802
negative regulation of glomerular mesangial cell proliferationGO:007212510.799
atrial septum primum morphogenesisGO:000328930.799
negative regulation of transcription from rna polymerase ii promoter by glucoseGO:000043310.798
positive regulation of nervous system developmentGO:00519622210.797
positive regulation of ureteric bud formationGO:007210730.796
cartilage development involved in endochondral bone morphogenesisGO:0060351240.796
foregut regionalizationGO:006042330.796
clara cell differentiationGO:006048640.795
transforming growth factor beta receptor signaling pathway involved in primitive streak formationGO:009001010.795
endocardial cushion developmentGO:0003197260.792
cerebellar granule cell differentiationGO:002170790.791
embryonic hindlimb morphogenesisGO:0035116320.791
forebrain developmentGO:00309003020.790
myotube differentiationGO:00149021050.790
cochlea morphogenesisGO:0090103220.789
negative regulation of immature t cell proliferationGO:003308730.788
morphogenesis of a branching epitheliumGO:00611381930.787
cell migration in hindbrainGO:0021535160.785
determination of left right asymmetry in lateral mesodermGO:000314050.780
regulation of heart morphogenesisGO:2000826220.779
regulation of branching involved in ureteric bud morphogenesisGO:0090189220.778
muscle fiber developmentGO:0048747760.772
regulation of osteoblast differentiationGO:0045667670.772
tendon cell differentiationGO:003599040.772
ventricular septum morphogenesisGO:0060412270.771
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.769
negative regulation of axon extensionGO:0030517190.768
lateral mesoderm morphogenesisGO:004836930.765
primitive streak formationGO:0090009100.762
negative regulation of mesenchymal cell proliferationGO:007220130.762
noradrenergic neuron developmentGO:000335830.758
regulation of vascular wound healingGO:006104320.757
regulation of mesodermal cell fate specificationGO:004266150.756
establishment of planar polarity involved in nephron morphogenesisGO:007204610.752
myelination in peripheral nervous systemGO:0022011190.750
positive regulation of odontogenesisGO:004248240.749
odontogenesisGO:0042476780.748
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.748
negative regulation of ossificationGO:0030279490.747
urogenital system developmentGO:00016552610.742
negative regulation of smoothened signaling pathwayGO:0045879250.742
glomerulus vasculature morphogenesisGO:007210360.741
vascular wound healingGO:006104230.741
protein import into nucleusGO:0006606950.741
olfactory bulb developmentGO:0021772300.740
mesenchymal stem cell maintenance involved in nephron morphogenesisGO:007203870.739
embryonic eye morphogenesisGO:0048048290.738
paraxial mesodermal cell differentiationGO:004834220.734
lung developmentGO:00303241640.734
face morphogenesisGO:0060325290.733
amine metabolic processGO:0009308450.731
regulation of lens epithelial cell proliferationGO:200110910.729
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart developmentGO:006131010.727
telencephalon regionalizationGO:0021978140.727
frontal suture morphogenesisGO:006036420.726
biomineral tissue developmentGO:0031214640.725
renal capsule specificationGO:007213010.721
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.720
inhibition of neuroepithelial cell differentiationGO:000208520.719
cell proliferation in external granule layerGO:0021924100.714
positive regulation of neuroblast proliferationGO:0002052190.713
embryonic digit morphogenesisGO:0042733560.711
specification of organ positionGO:001015930.709
regulation of glial cell differentiationGO:0045685410.708
carbon catabolite repression of transcriptionGO:004501310.705
epithelial cell maturation involved in prostate gland developmentGO:006074340.705
embryonic olfactory bulb interneuron precursor migrationGO:002183120.704
brain morphogenesisGO:0048854320.703
negative regulation of epithelial cell proliferationGO:0050680640.700
cardioblast migration to the midline involved in heart field formationGO:006097510.700
sensory organ morphogenesisGO:00905962420.695
Zebrafish Fly
cartilage developmentGO:00512161400.695
Zebrafish
renal inner medulla developmentGO:007205330.695
cellular ketone metabolic processGO:0042180840.693
pancreatic pp cell fate commitmentGO:000332920.692
cellular response to lipidGO:00713961450.689
regulation of secretionGO:00510462740.688
mesenchymal cell differentiationGO:00487621070.688
subpallium neuron fate commitmentGO:006016320.688
canonical wnt signaling pathwayGO:00600701300.687
positive regulation of mesenchymal cell proliferationGO:0002053330.684
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:007210830.684
ventricular cardiac muscle cell differentiationGO:0055012170.683
retinal bipolar neuron differentiationGO:006004050.683
metanephric comma shaped body morphogenesisGO:007227810.682
wnt signaling pathway involved in heart developmentGO:000330680.681
gliogenesisGO:00420631410.681
cardiac chamber developmentGO:00032051080.680
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016110.680
positive regulation of stem cell proliferationGO:2000648590.679
forebrain morphogenesisGO:0048853170.677
synapse organizationGO:00508081250.676
negative regulation of t cell proliferationGO:0042130380.675
neural fold formationGO:000184270.675
regulation of cartilage developmentGO:0061035440.673
sertoli cell fate commitmentGO:006001010.673
cerebral cortex tangential migrationGO:002180070.672
pericardium developmentGO:0060039160.670
regulation of nephron tubule epithelial cell differentiationGO:007218290.668
regulation of ureteric bud formationGO:007210630.667
spinal cord developmentGO:0021510810.666
positive regulation of cell proliferation in bone marrowGO:007186420.664
regulation of mesenchymal cell proliferation involved in ureter developmentGO:007219930.663
bmp signaling pathway involved in mesodermal cell fate specificationGO:006080310.663
regulation of cellular component biogenesisGO:00440871810.662
regulation of somitogenesisGO:001480760.661
regulation of neuron maturationGO:001404150.660
positive regulation of vascular wound healingGO:003547010.654
lateral mesoderm formationGO:004837030.654
ureteric bud morphogenesisGO:0060675620.653
prostate gland morphogenesisGO:0060512320.653
cell type specific apoptotic processGO:00972852680.648
pyramidal neuron developmentGO:002186080.648
regulation of protein targetingGO:1903533610.648
spinal cord motor neuron differentiationGO:0021522350.648
Zebrafish
epithelial to mesenchymal transitionGO:0001837470.647
positive regulation of cell developmentGO:00107202370.646
retina development in camera type eyeGO:00600411190.645
Zebrafish
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:200015010.643
embryonic camera type eye developmentGO:0031076360.642
Zebrafish
positive regulation of lens epithelial cell proliferationGO:200111110.641
regulation of cellular ketone metabolic processGO:0010565660.640
positive regulation of bone mineralizationGO:0030501120.640
response to growth factorGO:00708481980.640
inner ear morphogenesisGO:00424721010.639
Zebrafish
heart morphogenesisGO:00030071780.637
hindbrain morphogenesisGO:0021575460.634
digestive tract morphogenesisGO:00485461470.634
Zebrafish
optic vesicle morphogenesisGO:000340420.633
kidney developmentGO:00018222130.633
regulation of establishment of planar polarityGO:0090175280.632
blood vessel morphogenesisGO:00485142850.631
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferationGO:004434310.625
positive regulation of cell motilityGO:20001471160.625
canonical wnt signaling pathway involved in neural crest cell differentiationGO:004433510.619
muscle tissue developmentGO:00605373080.619
lateral motor column neuron migrationGO:009747730.611
cellular response to growth factor stimulusGO:00713631970.611
positive regulation of mesenchymal cell proliferation involved in ureter developmentGO:200072930.605
forebrain ventricular zone progenitor cell divisionGO:002186960.602
metanephric nephron tubule morphogenesisGO:007228270.601
cardiac ventricle developmentGO:0003231830.599
Zebrafish
regulation of cardioblast differentiationGO:005189030.598
wound healing spreading of cellsGO:004431980.597
cell proliferation involved in metanephros developmentGO:007220390.597
muscular septum morphogenesisGO:000315040.596
positive regulation of cartilage developmentGO:0061036180.591
cellular response to cholesterolGO:007139720.589
hippocampus developmentGO:0021766520.589
mammary gland morphogenesisGO:0060443540.589
paraxial mesodermal cell fate commitmentGO:004834320.588
renal vesicle developmentGO:0072087170.586
regulation of odontogenesisGO:0042481180.584
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specificationGO:002191340.584
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesisGO:007230930.581
metencephalon developmentGO:0022037890.579
organ growthGO:00352651170.579
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.579
cranial nerve developmentGO:0021545410.577
Rat
digestive system developmentGO:00551232000.575
regulation of cell cycleGO:00517262810.574
Fly
commitment of multipotent stem cells to neuronal lineage in forebrainGO:002189830.571
nephron morphogenesisGO:0072028690.570
regulation of transcription from rna polymerase iii promoterGO:000635920.570
endoderm developmentGO:0007492450.569
regulation of bone mineralizationGO:0030500310.568
branching morphogenesis of an epithelial tubeGO:00487541590.567
lung field specificationGO:006042430.564
mesenchymal cell proliferation involved in ureter developmentGO:007219840.563
atrioventricular bundle cell differentiationGO:000316710.562
negative regulation of cell cycleGO:00457861230.562
Fly
negative regulation of cardiac muscle tissue developmentGO:005502680.561
skeletal system morphogenesisGO:00487052030.560
Zebrafish
metanephric mesenchymal cell proliferation involved in metanephros developmentGO:007213620.560
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferationGO:200008110.556
glomerular mesangial cell differentiationGO:007200830.555
pallium developmentGO:00215431200.553
somatic motor neuron differentiationGO:002152360.551
Zebrafish
oocyte axis specificationGO:000730920.550
carbohydrate homeostasisGO:00335001280.549
metanephros morphogenesisGO:0003338240.548
regulation of mapk cascadeGO:00434082480.548
subpallium cell proliferation in forebrainGO:002201210.544
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190121390.544
negative regulation of epidermis developmentGO:004568390.541
bone morphogenesisGO:0060349780.537
positive regulation of smoothened signaling pathwayGO:0045880230.537
cellular response to organic cyclic compoundGO:0071407870.536
heart inductionGO:000312920.535
glial cell differentiationGO:00100011310.535
lateral mesodermal cell differentiationGO:004837130.534
myotube cell developmentGO:0014904600.532
nephron epithelium morphogenesisGO:0072088680.530
transforming growth factor beta receptor signaling pathwayGO:0007179710.529
semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:007152710.528
endocardial cushion formationGO:0003272130.528
cloacal septationGO:006019720.522
regulation of gastrulationGO:0010470160.522
rhombomere 3 developmentGO:002156940.519
paraxial mesoderm morphogenesisGO:0048340100.518
regulation of epithelial cell proliferation involved in lung morphogenesisGO:200079450.515
determination of left right symmetryGO:0007368800.515
regulation of oligodendrocyte differentiationGO:0048713230.515
spemann organizer formationGO:006006120.514
photoreceptor cell fate commitmentGO:004655220.514
craniofacial suture morphogenesisGO:0097094100.512
lateral sprouting involved in mammary gland duct morphogenesisGO:006059920.512
branching involved in labyrinthine layer morphogenesisGO:006067090.507
chondrocyte hypertrophyGO:000341540.505

Smo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.985
musculoskeletal system diseaseDOID:1700.985
connective tissue diseaseDOID:6500.985
bone development diseaseDOID:008000600.801
bone diseaseDOID:008000100.801