Mus musculus

0 known processes

Pdha2

pyruvate dehydrogenase E1 alpha 2

(Aliases: Pdhal)

Pdha2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nitrogen compound transportGO:00717052710.114
sperm motilityGO:0030317470.110
nucleobase containing small molecule metabolic processGO:00550863520.108
cellular aldehyde metabolic processGO:0006081120.097
regulation of cytokine productionGO:00018172660.097
purine ribonucleotide metabolic processGO:00091502900.095
response to radiationGO:00093141650.094
purine nucleotide metabolic processGO:00061633020.091
fertilizationGO:00095661270.089
negative regulation of immune system processGO:00026832090.085
ribose phosphate metabolic processGO:00196932910.077
endocytosisGO:00068971680.076
spermatogenesisGO:00072832840.073
immune effector processGO:00022523210.071
ion transmembrane transportGO:00342203610.067
immune response regulating signaling pathwayGO:00027641250.065
conditioned taste aversionGO:000166140.063
nucleoside phosphate biosynthetic processGO:1901293790.062
purine ribonucleotide biosynthetic processGO:0009152590.060
action potentialGO:0001508780.058
nucleoside phosphate catabolic processGO:19012922220.056
nucleoside phosphate metabolic processGO:00067533380.056
nucleoside metabolic processGO:00091162460.055
negative regulation of cell cycleGO:00457861230.052
regulation of purine nucleotide metabolic processGO:19005421690.052
ribonucleotide metabolic processGO:00092592910.051
posttranscriptional regulation of gene expressionGO:00106081550.051
positive regulation of programmed cell deathGO:00430682180.050
regulation of nucleotide metabolic processGO:00061401690.050
generation of precursor metabolites and energyGO:00060911030.050
apoptotic signaling pathwayGO:00971903060.048
feeding behaviorGO:0007631620.048
multicellular organismal signalingGO:0035637910.048
positive regulation of cell deathGO:00109422240.046
peptide transportGO:00158331330.046
purine ribonucleoside triphosphate metabolic processGO:00092052200.046
multicellular organismal homeostasisGO:00488711640.046
male gamete generationGO:00482322850.045
organonitrogen compound catabolic processGO:19015652640.044
nucleotide metabolic processGO:00091173320.044
purine containing compound metabolic processGO:00725213110.043
cytokine productionGO:00018163190.043
regulation of secretion by cellGO:19035302490.042
organonitrogen compound biosynthetic processGO:19015661920.042
regulation of proteolysisGO:00301621640.041
positive regulation of apoptotic processGO:00430652170.041
spermatid developmentGO:00072861080.040
glycosyl compound catabolic processGO:19016582060.040
amine metabolic processGO:0009308450.040
intracellular protein transportGO:00068862040.040
transmembrane transportGO:00550854120.040
purine nucleoside triphosphate metabolic processGO:00091442260.039
regulation of kinase activityGO:00435492490.039
purine nucleoside catabolic processGO:00061522050.039
heart contractionGO:0060047930.038
protein modification by small protein conjugationGO:00324461870.038
positive regulation of cytokine productionGO:00018191740.038
organic hydroxy compound metabolic processGO:19016152030.038
protein maturationGO:00516041760.038
ameboidal type cell migrationGO:00016671280.037
rhythmic processGO:00485111740.037
purine containing compound catabolic processGO:00725232130.036
histamine induced gastric acid secretionGO:000169710.036
cellular amino acid metabolic processGO:00065201030.036
ribonucleoside metabolic processGO:00091192450.036
forebrain developmentGO:00309003020.036
positive regulation of cellular amine metabolic processGO:003324050.036
camera type eye developmentGO:00430102660.035
regulation of cell motilityGO:20001452360.035
positive regulation of angiogenesisGO:0045766460.035
regulation of cellular ketone metabolic processGO:0010565660.035
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.035
small gtpase mediated signal transductionGO:0007264970.034
blood circulationGO:00080151950.034
nucleotide biosynthetic processGO:0009165780.034
hormone secretionGO:00468791280.034
regulation of cellular catabolic processGO:00313292420.033
protein processingGO:00164851630.033
learning or memoryGO:00076111480.033
ribonucleoside triphosphate metabolic processGO:00091992200.033
natural killer cell activationGO:0030101440.032
cellular nitrogen compound catabolic processGO:00442702800.032
organophosphate biosynthetic processGO:00904071220.032
organic cyclic compound catabolic processGO:19013612950.032
regulation of defense responseGO:00313472330.032
regulation of hormone levelsGO:00108172110.032
single fertilizationGO:0007338820.031
nucleoside catabolic processGO:00091642060.031
transmission of nerve impulseGO:0019226760.031
neuronal action potentialGO:0019228540.031
oxidation reduction processGO:00551143420.031
protein localization to organelleGO:00333651850.030
regulation of response to woundingGO:19030341890.030
regulation of lymphocyte activationGO:00512492400.030
cellular ketone metabolic processGO:0042180840.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
aromatic compound catabolic processGO:00194392860.030
regulation of neuron differentiationGO:00456642810.029
peptide secretionGO:00027901140.029
protein targetingGO:00066051430.029
single organism nuclear importGO:1902593950.029
nuclear divisionGO:00002801580.029
epithelial cell migrationGO:0010631630.029
proteolysis involved in cellular protein catabolic processGO:00516031470.029
angiogenesisGO:00015252010.029
regulation of cellular carbohydrate metabolic processGO:0010675750.029
purine ribonucleoside catabolic processGO:00461302050.029
nucleoside triphosphate catabolic processGO:00091432050.028
tissue remodelingGO:00487711020.028
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.028
progesterone metabolic processGO:004244840.028
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.027
cation transmembrane transportGO:00986552660.027
purine nucleoside triphosphate catabolic processGO:00091462030.027
regulation of secretionGO:00510462740.027
development of primary male sexual characteristicsGO:0046546880.027
tissue migrationGO:0090130680.027
nucleocytoplasmic transportGO:00069131390.027
cyclic nucleotide metabolic processGO:0009187590.027
positive regulation of cellular catabolic processGO:00313311480.027
androgen biosynthetic processGO:000670240.027
regulation of vesicle mediated transportGO:00606271390.027
negative regulation of interleukin 13 productionGO:003269620.027
modification dependent macromolecule catabolic processGO:00436321330.027
regulation of reproductive processGO:2000241660.026
regulation of cellular amine metabolic processGO:0033238200.026
positive regulation of transferase activityGO:00513471670.026
muscle tissue developmentGO:00605373080.026
cellular chemical homeostasisGO:00550822150.025
regulation of leukocyte mediated immunityGO:00027031040.025
guanosine containing compound catabolic processGO:19010691440.025
striated muscle contractionGO:0006941450.025
purine ribonucleotide catabolic processGO:00091542080.025
regulation of translationGO:0006417710.025
protein modification by small protein conjugation or removalGO:00706472070.025
regulation of apoptotic signaling pathwayGO:20012331970.024
ribonucleotide biosynthetic processGO:0009260590.024
glycolytic processGO:0006096200.024
embryonic organ morphogenesisGO:00485622760.024
nucleoside triphosphate metabolic processGO:00091412300.024
regulation of lymphocyte mediated immunityGO:0002706840.024
circadian rhythmGO:00076231140.024
regulation of hormone secretionGO:0046883880.023
regulation of cell cycleGO:00517262810.023
carbohydrate derivative biosynthetic processGO:19011371830.023
regulation of protein processingGO:0070613960.023
positive regulation of secretionGO:00510471300.023
positive regulation of blood circulationGO:1903524220.023
gonad developmentGO:00084061410.023
establishment of meiotic spindle orientationGO:005129610.023
germ cell developmentGO:00072811850.023
positive regulation of protein kinase b signalingGO:0051897320.022
negative regulation of lymphocyte activationGO:0051250910.022
epithelium migrationGO:0090132630.022
regulation of angiogenesisGO:0045765810.022
t helper 2 cell cytokine productionGO:003574540.022
positive regulation of gtp catabolic processGO:0033126850.022
positive regulation of kinase activityGO:00336741550.022
mitotic cell cycle processGO:19030471590.022
regulation of cell migrationGO:00303342190.022
epithelial cell developmentGO:00020641590.022
neuron deathGO:00709971540.022
development of primary sexual characteristicsGO:00451371430.022
protein secretionGO:00093061110.022
negative regulation of interleukin 5 productionGO:003271440.022
regulation of multi organism processGO:00439001110.021
glycosyl compound metabolic processGO:19016572460.021
regulation of hydrolase activityGO:00513362460.021
regulation of cell adhesion mediated by integrinGO:0033628130.021
erk1 and erk2 cascadeGO:0070371770.021
cellular divalent inorganic cation homeostasisGO:00725031270.021
cardiac muscle contractionGO:0060048320.021
purine containing compound biosynthetic processGO:0072522700.021
negative regulation of cell developmentGO:00107211690.021
pyruvate metabolic processGO:0006090280.021
skeletal system developmentGO:00015013560.021
purine nucleoside metabolic processGO:00422782410.021
macromolecule catabolic processGO:00090572810.021
regulation of carbohydrate metabolic processGO:0006109750.021
inflammatory responseGO:00069542440.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
ribonucleotide catabolic processGO:00092612080.020
nucleotide catabolic processGO:00091662170.020
carbohydrate derivative catabolic processGO:19011362310.020
negative regulation of cell activationGO:00508661110.020
regulation of sequence specific dna binding transcription factor activityGO:00510901060.020
regulation of membrane potentialGO:00423911920.020
regulation of cell projection organizationGO:00313442060.020
purine nucleotide catabolic processGO:00061952110.020
multicellular organism growthGO:00352641610.020
male gonad developmentGO:0008584880.019
dibenzo p dioxin metabolic processGO:001889410.019
negative regulation of growthGO:0045926990.019
cytoplasmic transportGO:00164822340.019
positive regulation of vasoconstrictionGO:004590740.019
regulation of protein catabolic processGO:00421761080.019
regulation of synaptic plasticityGO:0048167870.019
pallium developmentGO:00215431200.019
protein catabolic processGO:00301632210.019
carbohydrate catabolic processGO:0016052320.019
cellular protein complex assemblyGO:00436231160.019
cellular macromolecule catabolic processGO:00442652060.019
cellular lipid metabolic processGO:00442553230.019
response to light stimulusGO:00094161350.019
cellular homeostasisGO:00197252400.019
b cell activationGO:00421131610.019
negative regulation of phosphorus metabolic processGO:00105631840.019
positive regulation of proteolysisGO:0045862850.019
calcium ion homeostasisGO:00550741270.019
male meiosisGO:0007140370.019
ribonucleoside triphosphate catabolic processGO:00092031990.019
cellular amine metabolic processGO:0044106440.018
cd4 positive alpha beta t cell cytokine productionGO:003574340.018
negative regulation of protein maturationGO:1903318790.018
heart processGO:0003015940.018
muscle system processGO:00030121410.018
determination of left right asymmetry in nervous systemGO:003554510.018
response to organonitrogen compoundGO:00102432460.018
circulatory system processGO:00030131970.018
cellular component assembly involved in morphogenesisGO:00109271390.018
peptide hormone secretionGO:00300721090.018
cognitionGO:00508901490.018
cell type specific apoptotic processGO:00972852680.018
heart morphogenesisGO:00030071780.018
sperm egg recognitionGO:0035036370.018
membrane organizationGO:00610242450.018
regulation of peptide hormone secretionGO:0090276750.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
insulin secretionGO:0030073890.018
regulation of transferase activityGO:00513382630.018
cellular response to extracellular stimulusGO:0031668810.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
peptidyl tyrosine modificationGO:00182121450.018
regulation of blood circulationGO:1903522930.018
telencephalon developmentGO:00215371860.017
hematopoietic progenitor cell differentiationGO:00022441430.017
regulation of leukocyte differentiationGO:19021051590.017
glucose homeostasisGO:00425931280.017
muscle contractionGO:00069361010.017
sensory perceptionGO:00076002450.017
blood vessel morphogenesisGO:00485142850.017
regulation of epithelial cell proliferationGO:00506781410.017
immune response activating signal transductionGO:00027571160.017
regulation of metal ion transportGO:00109591060.017
amide transportGO:00428861380.017
ras protein signal transductionGO:0007265770.017
ribonucleoside catabolic processGO:00424542060.017
heterocycle catabolic processGO:00467002800.017
purine ribonucleoside metabolic processGO:00461282410.016
regulation of innate immune responseGO:0045088910.016
regulation of feeding behaviorGO:006025930.016
gtp metabolic processGO:00460391440.016
regulation of nucleoside metabolic processGO:00091181300.016
cellular response to peptide hormone stimulusGO:0071375920.016
reactive oxygen species biosynthetic processGO:190340980.016
innate immune responseGO:00450871570.016
positive regulation of protein modification processGO:00314012990.016
nuclear transportGO:00511691390.016
response to growth factorGO:00708481980.016
regulation of complement activation classical pathwayGO:003045010.016
purine nucleotide biosynthetic processGO:0006164650.016
axon ensheathmentGO:0008366760.016
respiratory system developmentGO:00605411900.016
respiratory tube developmentGO:00303231670.016
cyclic nucleotide biosynthetic processGO:0009190440.016
cell recognitionGO:0008037830.016
phenol containing compound metabolic processGO:0018958600.016
trabecular meshwork developmentGO:000293020.016
response to organic cyclic compoundGO:00140701980.016
regulation of eosinophil migrationGO:200041620.016
limbic system developmentGO:0021761720.015
cell cell recognitionGO:0009988440.015
pattern specification involved in metanephros developmentGO:007226840.015
organophosphate catabolic processGO:00464342320.015
norepinephrine transportGO:001587420.015
protein kinase b signalingGO:0043491740.015
negative regulation of molecular functionGO:00440922580.015
cell maturationGO:00484691270.015
negative regulation of protein processingGO:0010955790.015
ubiquitin dependent protein catabolic processGO:00065111290.015
organelle fissionGO:00482851700.015
anion transportGO:00068201770.015
renal vesicle inductionGO:007203430.015
l amino acid transportGO:0015807320.015
negative regulation of cellular component organizationGO:00511291940.015
response to inorganic substanceGO:0010035960.015
regulation of mitotic cell cycleGO:00073461260.015
central nervous system neuron differentiationGO:00219531620.015
regulation of b cell activationGO:0050864810.015
gtp catabolic processGO:00061841430.015
response to acid chemicalGO:00011011110.015
response to retinoic acidGO:0032526560.015
positive regulation of heart rate by epinephrine norepinephrineGO:000199640.015
cellular response to molecule of bacterial originGO:0071219830.015
regulation of cellular amino acid metabolic processGO:000652150.015
negative regulation of protein metabolic processGO:00512482820.015
protein importGO:00170381010.015
regulation of system processGO:00440572000.015
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.014
positive regulation of apoptotic signaling pathwayGO:2001235950.014
positive regulation of glycolytic processGO:004582140.014
ossificationGO:00015032160.014
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199730.014
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122840.014
regulation of mapk cascadeGO:00434082480.014
monocarboxylic acid metabolic processGO:00327871910.014
rna interferenceGO:001624620.014
cardiac chamber developmentGO:00032051080.014
negative regulation of humoral immune response mediated by circulating immunoglobulinGO:000292430.014
positive regulation of phagocytosisGO:0050766260.014
negative regulation of leukocyte mediated immunityGO:0002704290.014
regulation of adaptive immune responseGO:0002819900.014
entry into cell of other organism involved in symbiotic interactionGO:0051806150.014
spleen developmentGO:0048536390.014
ear morphogenesisGO:00424711180.014
striated muscle tissue developmentGO:00147062930.014
myeloid cell homeostasisGO:00022621140.014
regulation of inflammatory responseGO:00507271470.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.014
microtubule based processGO:00070172360.014
regulation of vasculature developmentGO:1901342880.014
regulation of purine nucleotide catabolic processGO:00331211220.014
hippocampus developmentGO:0021766520.014
regulation of nucleotide catabolic processGO:00308111220.013
response to alkaloidGO:0043279340.013
homeostasis of number of cellsGO:00488722100.013
sensory organ morphogenesisGO:00905962420.013
cellular response to organonitrogen compoundGO:00714171450.013
mineralocorticoid biosynthetic processGO:000670510.013
t cell mediated immunityGO:0002456500.013
regulation of nuclear divisionGO:0051783560.013
ribose phosphate biosynthetic processGO:0046390590.013
mitochondrion organizationGO:00070051340.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
negative regulation of cytokine productionGO:0001818840.013
chemotaxisGO:00069352470.013
neuroblast proliferationGO:0007405490.013
regulation of protein stabilityGO:0031647520.013
detection of abiotic stimulusGO:0009582600.013
epithelial cell proliferationGO:00506731740.013
negative regulation of interleukin 13 secretionGO:200066610.013
cellular response to hormone stimulusGO:00328701500.013
regulation of interleukin 13 secretionGO:200066520.013
activation of immune responseGO:00022531380.013
gastrin induced gastric acid secretionGO:000169810.013
regulation of establishment of protein localizationGO:00702011810.013
neuron neuron synaptic transmissionGO:0007270690.013
tissue homeostasisGO:00018941150.013
adaptive immune responseGO:00022501550.013
carbohydrate homeostasisGO:00335001280.012
positive regulation of fat cell differentiationGO:0045600320.012
translationGO:0006412930.012
substantia nigra developmentGO:002176220.012
ensheathment of neuronsGO:0007272760.012
mapk cascadeGO:00001652810.012
negative regulation of defense responseGO:0031348770.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
midgut developmentGO:000749440.012
cell fate commitmentGO:00451652100.012
protein ubiquitinationGO:00165671710.012
modification dependent protein catabolic processGO:00199411330.012
positive regulation of nucleotide biosynthetic processGO:0030810260.012
digestive tract morphogenesisGO:00485461470.012
reactive nitrogen species metabolic processGO:200105700.012
asymmetric neuroblast divisionGO:005505910.012
gliogenesisGO:00420631410.012
epithelial cell morphogenesisGO:0003382410.012
regulation of monocyte chemotaxisGO:009002530.012
negative regulation of wnt signaling pathwayGO:0030178730.012
cardiac chamber morphogenesisGO:0003206930.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
activation of adenylate cyclase activityGO:000719040.012
receptor mediated endocytosisGO:0006898510.012
regulation of protein secretionGO:0050708820.012
cellular calcium ion homeostasisGO:00068741190.012
positive regulation of the force of heart contraction by chemical signalGO:000309930.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.012
testosterone biosynthetic processGO:006137020.012
positive regulation of protein kinase activityGO:00458601440.012
alpha amino acid metabolic processGO:1901605590.012
developmental maturationGO:00217001930.012
regulation of cell cycle phase transitionGO:1901987770.012
negative regulation of multi organism processGO:0043901680.012
regulation of blood pressureGO:0008217930.012
interleukin 5 secretionGO:007260320.012
regulation of ion transportGO:00432692150.012
visual learningGO:0008542440.012
binding of sperm to zona pellucidaGO:0007339340.012
myelinationGO:0042552740.012
negative regulation of t cell activationGO:0050868650.012
regulation of nodal signaling pathwayGO:190010740.011
response to phenylpropanoidGO:0080184220.011
regulation of neuron projection developmentGO:00109751690.011
regulation of cellular component biogenesisGO:00440871810.011
spermatid differentiationGO:00485151150.011
t cell activationGO:00421102890.011
sensitizationGO:004696020.011
pancreas developmentGO:0031016570.011
establishment of protein localization to organelleGO:00725941180.011
protein localization to nucleusGO:00345041210.011
trachea formationGO:006044030.011
organic anion transportGO:00157111370.011
amino acid transportGO:0006865610.011
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.011
cellular metal ion homeostasisGO:00068751510.011
negative regulation of leukocyte proliferationGO:0070664460.011
regulation of cellular response to stressGO:00801351590.011
leukocyte mediated immunityGO:00024431740.011
regulation of action potentialGO:009890040.011
oocyte developmentGO:0048599330.011
gene silencing by mirnaGO:0035195100.011
bronchiole developmentGO:006043530.011
negative regulation of secretion by cellGO:1903531540.011
positive regulation of cell developmentGO:00107202370.011
cardiac muscle tissue developmentGO:00487381300.011
regulation of endocytosisGO:0030100690.011
response to oxidative stressGO:00069791230.011
vasodilationGO:0042311280.011
response to extracellular stimulusGO:00099911270.011
cellular response to inorganic substanceGO:0071241370.011
response to molecule of bacterial originGO:00022371430.011
regulation of cellular protein catabolic processGO:1903362610.011
rho protein signal transductionGO:0007266320.011
positive regulation of cyclic nucleotide metabolic processGO:0030801240.011
leukocyte apoptotic processGO:0071887710.011
glucan metabolic processGO:0044042320.011
cellular protein catabolic processGO:00442571550.011
ventricular cardiac myofibril assemblyGO:005500530.011
regulation of glucose metabolic processGO:0010906600.011
regulation of organelle organizationGO:00330432890.011
oocyte differentiationGO:0009994350.011
metanephric renal vesicle morphogenesisGO:0072283120.011
regulation of erk1 and erk2 cascadeGO:0070372710.011
gland developmentGO:00487323300.011
multicellular organismal response to stressGO:0033555620.010
positive regulation of protein phosphorylationGO:00019342420.010
phagocytosisGO:0006909660.010
regulation of cell adhesionGO:00301551540.010
av node cell to bundle of his cell communicationGO:008606720.010
tube closureGO:0060606910.010
skeletal muscle organ developmentGO:00605381630.010
norepinephrine secretionGO:004824320.010
phospholipase c activating serotonin receptor signaling pathwayGO:000720810.010
positive regulation of cell motilityGO:20001471160.010
eosinophil migrationGO:007267730.010
defense response to virusGO:0051607680.010
defecationGO:003042110.010
mitotic cell cycleGO:00002781950.010
fat cell differentiationGO:00454441600.010
somitogenesisGO:0001756690.010
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.010

Pdha2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
congenital adrenal hyperplasiaDOID:005081100.025
disease of metabolismDOID:001466700.025
lipid metabolism disorderDOID:314600.025
steroid inherited metabolic disorderDOID:170100.025
inherited metabolic disorderDOID:65500.025
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
sensory system diseaseDOID:005015500.010