Mus musculus

5 known processes

Pdha1

pyruvate dehydrogenase E1 alpha 1

(Aliases: Pdha-1)

Pdha1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
energy derivation by oxidation of organic compoundsGO:0015980770.361
oxidation reduction processGO:00551143420.326
generation of precursor metabolites and energyGO:00060911030.289
coenzyme metabolic processGO:0006732520.243
sulfur compound biosynthetic processGO:0044272370.201
nadh metabolic processGO:000673410.150
monocarboxylic acid metabolic processGO:00327871910.150
cellular amino acid metabolic processGO:00065201030.139
organic acid biosynthetic processGO:0016053860.119
cofactor metabolic processGO:0051186800.118
coenzyme biosynthetic processGO:0009108230.117
nucleobase containing small molecule metabolic processGO:00550863520.107
cellular ketone metabolic processGO:0042180840.104
acetyl coa biosynthetic processGO:000608550.094
cation transportGO:00068123990.084
acetyl coa biosynthetic process from pyruvateGO:000608630.080
regulation of mitochondrial fissionGO:009014030.077
small molecule catabolic processGO:0044282710.072
acyl coa biosynthetic processGO:007161670.070
regulation of cellular ketone metabolic processGO:0010565660.067
cellular amine metabolic processGO:0044106440.067
purine ribonucleoside metabolic processGO:00461282410.065
transmembrane transportGO:00550854120.062
fatty acid oxidationGO:0019395280.061
purine ribonucleotide metabolic processGO:00091502900.060
acyl coa metabolic processGO:0006637190.060
nucleotide metabolic processGO:00091173320.058
ion transmembrane transportGO:00342203610.057
carboxylic acid biosynthetic processGO:0046394860.056
carbohydrate metabolic processGO:00059752300.050
mitochondrion organizationGO:00070051340.050
sulfur compound metabolic processGO:00067901000.048
small molecule biosynthetic processGO:00442831320.047
thioester biosynthetic processGO:003538470.047
cellular homeostasisGO:00197252400.047
regulation of membrane potentialGO:00423911920.046
t cell activationGO:00421102890.045
nucleoside metabolic processGO:00091162460.045
endocytosisGO:00068971680.042
Worm
nucleoside phosphate biosynthetic processGO:1901293790.042
gland developmentGO:00487323300.042
purine nucleoside metabolic processGO:00422782410.042
organophosphate biosynthetic processGO:00904071220.041
intrinsic apoptotic signaling pathwayGO:00971931320.041
lipid oxidationGO:0034440290.041
negative regulation of cellular amine metabolic processGO:003323910.040
atp metabolic processGO:0046034750.040
cellular lipid metabolic processGO:00442553230.040
nucleoside phosphate metabolic processGO:00067533380.040
organonitrogen compound biosynthetic processGO:19015661920.039
lipid biosynthetic processGO:00086101790.039
cellular carbohydrate metabolic processGO:00442621190.038
regulation of cellular amine metabolic processGO:0033238200.038
regulation of mitochondrion organizationGO:0010821270.038
amine metabolic processGO:0009308450.037
action potentialGO:0001508780.037
membrane organizationGO:00610242450.037
organic acid catabolic processGO:0016054510.037
organic cyclic compound catabolic processGO:19013612950.036
regulation of cellular amino acid metabolic processGO:000652150.035
organonitrogen compound catabolic processGO:19015652640.035
heterocycle catabolic processGO:00467002800.034
regulation of organelle organizationGO:00330432890.034
carboxylic acid catabolic processGO:0046395510.033
ribonucleotide metabolic processGO:00092592910.033
cation transmembrane transportGO:00986552660.033
forebrain developmentGO:00309003020.032
hexose metabolic processGO:0019318980.032
organic hydroxy compound metabolic processGO:19016152030.032
lipid localizationGO:00108761260.031
cellular respirationGO:0045333380.031
nucleoside triphosphate metabolic processGO:00091412300.031
synapse organizationGO:00508081250.030
carbohydrate derivative biosynthetic processGO:19011371830.030
aromatic compound catabolic processGO:00194392860.030
striated muscle tissue developmentGO:00147062930.030
ribose phosphate metabolic processGO:00196932910.029
regulation of cell activationGO:00508652890.029
cellular amino acid catabolic processGO:0009063250.028
maintenance of locationGO:0051235890.028
inorganic ion transmembrane transportGO:00986602340.028
glycosyl compound metabolic processGO:19016572460.027
spermatogenesisGO:00072832840.027
cell type specific apoptotic processGO:00972852680.027
transmission of nerve impulseGO:0019226760.027
muscle tissue developmentGO:00605373080.026
blood vessel morphogenesisGO:00485142850.026
negative regulation of cell proliferationGO:00082852960.026
positive regulation of apoptotic processGO:00430652170.026
purine nucleoside monophosphate metabolic processGO:0009126810.026
monocarboxylic acid biosynthetic processGO:0072330610.026
regulation of protein transportGO:00512231630.026
cation homeostasisGO:00550802120.025
lymphocyte proliferationGO:00466511640.025
regulation of transmembrane transportGO:00347621280.025
apoptotic mitochondrial changesGO:0008637480.025
ribonucleoside metabolic processGO:00091192450.024
nucleoside monophosphate metabolic processGO:0009123850.024
organelle fissionGO:00482851700.024
citrate metabolic processGO:000610130.024
purine nucleotide biosynthetic processGO:0006164650.024
positive regulation of organelle organizationGO:00106381280.024
regulation of cellular response to stressGO:00801351590.023
anatomical structure homeostasisGO:00602491450.023
cell adhesionGO:00071553290.023
neural tube formationGO:00018411080.023
regulation of secretion by cellGO:19035302490.023
regulation of protein localizationGO:00328802310.023
inorganic cation transmembrane transportGO:00986622070.023
regulation of lymphocyte activationGO:00512492400.022
nucleotide biosynthetic processGO:0009165780.022
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
thioester metabolic processGO:0035383190.022
amp metabolic processGO:004603340.022
angiogenesisGO:00015252010.021
glycerophospholipid metabolic processGO:0006650710.021
regulation of apoptotic signaling pathwayGO:20012331970.021
purine containing compound metabolic processGO:00725213110.021
monosaccharide metabolic processGO:00059961060.021
neuron apoptotic processGO:00514021420.021
nuclear transportGO:00511691390.021
monosaccharide biosynthetic processGO:0046364440.021
multi multicellular organism processGO:00447061090.020
telencephalon developmentGO:00215371860.020
sensory perceptionGO:00076002450.020
posttranscriptional regulation of gene expressionGO:00106081550.020
heart morphogenesisGO:00030071780.020
positive regulation of cellular amine metabolic processGO:003324050.019
regulation of intracellular transportGO:00323861590.019
ras protein signal transductionGO:0007265770.019
nucleocytoplasmic transportGO:00069131390.019
positive regulation of protein kinase activityGO:00458601440.019
regulation of ion transmembrane transportGO:00347651190.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
succinyl coa metabolic processGO:000610410.019
nitrogen compound transportGO:00717052710.019
cardiac muscle tissue developmentGO:00487381300.019
negative regulation of molecular functionGO:00440922580.019
mitochondrial fusionGO:000805390.019
cellular chemical homeostasisGO:00550822150.019
muscle cell differentiationGO:00426922610.019
purine ribonucleotide catabolic processGO:00091542080.019
cellular ion homeostasisGO:00068731650.019
negative regulation of intracellular signal transductionGO:19025321670.019
multicellular organismal signalingGO:0035637910.018
ossificationGO:00015032160.018
fatty acid metabolic processGO:00066311210.018
organic hydroxy compound biosynthetic processGO:1901617770.018
cytokine productionGO:00018163190.018
glycogen metabolic processGO:0005977320.018
locomotory behaviorGO:00076261950.018
regulation of neuron differentiationGO:00456642810.018
ribonucleoside monophosphate metabolic processGO:0009161800.018
cellular response to hormone stimulusGO:00328701500.018
carbohydrate biosynthetic processGO:0016051740.018
iron sulfur cluster assemblyGO:001622630.018
protein processingGO:00164851630.018
regulation of mapk cascadeGO:00434082480.018
regulation of carbohydrate metabolic processGO:0006109750.017
cellular response to molecule of bacterial originGO:0071219830.017
nicotinamide nucleotide metabolic processGO:0046496120.017
homeostasis of number of cellsGO:00488722100.017
morphogenesis of embryonic epitheliumGO:00163311590.017
response to oxidative stressGO:00069791230.017
epithelial tube morphogenesisGO:00605623030.017
phagocytosisGO:0006909660.017
response to organonitrogen compoundGO:00102432460.017
response to inorganic substanceGO:0010035960.017
dicarboxylic acid metabolic processGO:0043648180.017
dna metabolic processGO:00062593030.017
phospholipid metabolic processGO:0006644870.017
regulation of ion transportGO:00432692150.017
ribose phosphate biosynthetic processGO:0046390590.017
cellular response to biotic stimulusGO:0071216920.017
epithelial cell proliferationGO:00506731740.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
positive regulation of cell deathGO:00109422240.017
myeloid cell differentiationGO:00300992330.017
regulation of anatomical structure sizeGO:00900661780.017
regulation of protein kinase activityGO:00458592320.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
primary neural tube formationGO:0014020950.016
regulation of metal ion transportGO:00109591060.016
regulation of cellular carbohydrate metabolic processGO:0010675750.016
purine containing compound biosynthetic processGO:0072522700.016
regulation of secretionGO:00510462740.016
engulfment of apoptotic cellGO:004365230.016
purine nucleotide catabolic processGO:00061952110.016
negative regulation of phosphorylationGO:00423261660.016
response to molecule of bacterial originGO:00022371430.016
regulation of glucose metabolic processGO:0010906600.016
ribonucleotide biosynthetic processGO:0009260590.016
purine ribonucleotide biosynthetic processGO:0009152590.016
negative regulation of phosphorus metabolic processGO:00105631840.016
alpha amino acid catabolic processGO:1901606180.016
protein secretionGO:00093061110.016
purine ribonucleoside biosynthetic processGO:0046129190.016
regulation of cytokine productionGO:00018172660.016
lymphocyte differentiationGO:00300982420.016
alcohol metabolic processGO:00060661160.016
skeletal system developmentGO:00015013560.015
cellular response to lipidGO:00713961450.015
energy reserve metabolic processGO:0006112390.015
regulation of cellular component biogenesisGO:00440871810.015
oxidoreduction coenzyme metabolic processGO:0006733160.015
mitotic cell cycleGO:00002781950.015
cardiocyte differentiationGO:0035051870.015
regulation of transferase activityGO:00513382630.015
leukocyte differentiationGO:00025213420.015
positive regulation of protein modification processGO:00314012990.015
negative regulation of cellular component organizationGO:00511291940.015
stem cell differentiationGO:00488632680.015
organelle localizationGO:00516401790.015
water soluble vitamin biosynthetic processGO:004236430.015
regulation of hydrolase activityGO:00513362460.014
response to oxygen radicalGO:0000305160.014
intracellular protein transportGO:00068862040.014
ribonucleoside catabolic processGO:00424542060.014
mitochondrial membrane organizationGO:0007006260.014
mapk cascadeGO:00001652810.014
ribonucleoside monophosphate biosynthetic processGO:000915690.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
cofactor transportGO:005118140.014
cofactor biosynthetic processGO:0051188410.014
regulation of homeostatic processGO:00328441820.014
small gtpase mediated signal transductionGO:0007264970.014
neural tube developmentGO:00219151600.014
response to lipopolysaccharideGO:00324961280.014
immune effector processGO:00022523210.014
peptidyl amino acid modificationGO:00181933360.014
anion transportGO:00068201770.014
cytoplasmic transportGO:00164822340.014
leukocyte proliferationGO:00706611720.014
hepaticobiliary system developmentGO:0061008670.014
4 hydroxyproline metabolic processGO:001947150.014
purine nucleotide metabolic processGO:00061633020.014
regulation of neuron deathGO:19012141340.014
multicellular organismal homeostasisGO:00488711640.014
innate immune responseGO:00450871570.014
regulation of ion transmembrane transporter activityGO:0032412540.014
carbohydrate derivative catabolic processGO:19011362310.014
neuron deathGO:00709971540.014
cellular response to lipopolysaccharideGO:0071222770.014
cellular response to organonitrogen compoundGO:00714171450.013
regulation of map kinase activityGO:00434051200.013
tricarboxylic acid metabolic processGO:007235050.013
calcium ion homeostasisGO:00550741270.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
positive regulation of mapk cascadeGO:00434101700.013
regulation of protein complex assemblyGO:0043254830.013
glucose metabolic processGO:0006006920.013
apoptotic signaling pathwayGO:00971903060.013
t cell proliferationGO:00420981200.013
divalent metal ion transportGO:00708381720.013
male gamete generationGO:00482322850.013
tube closureGO:0060606910.013
response to reactive oxygen speciesGO:0000302560.013
regulation of transporter activityGO:0032409570.013
pyridine nucleotide metabolic processGO:0019362120.013
ribonucleotide catabolic processGO:00092612080.013
regulation of neurotransmitter levelsGO:0001505870.013
protein oligomerizationGO:0051259670.013
circulatory system processGO:00030131970.013
response to organic cyclic compoundGO:00140701980.013
camera type eye developmentGO:00430102660.013
fatty acid catabolic processGO:0009062250.013
protein homooligomerizationGO:0051260430.013
cellular polysaccharide metabolic processGO:0044264380.013
positive regulation of cell activationGO:00508671580.012
nuclear divisionGO:00002801580.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
regulation of neuron apoptotic processGO:00435231220.012
negative regulation of cellular protein metabolic processGO:00322692470.012
meiotic nuclear divisionGO:00071261150.012
regulation of response to woundingGO:19030341890.012
metal ion homeostasisGO:00550651890.012
response to acid chemicalGO:00011011110.012
embryonic epithelial tube formationGO:00018381300.012
negative regulation of protein metabolic processGO:00512482820.012
response to steroid hormoneGO:0048545560.012
leukocyte mediated immunityGO:00024431740.012
protein localization to organelleGO:00333651850.012
respiratory system developmentGO:00605411900.012
positive regulation of cell developmentGO:00107202370.012
regulation of cell adhesionGO:00301551540.012
hydrogen transportGO:0006818350.012
response to nutrient levelsGO:00316671090.012
regulation of ras protein signal transductionGO:00465781140.012
glycosyl compound biosynthetic processGO:1901659210.012
inner mitochondrial membrane organizationGO:000700750.012
chromatin organizationGO:00063252060.012
actin cytoskeleton organizationGO:00300362200.012
tissue homeostasisGO:00018941150.012
neuronal action potentialGO:0019228540.012
hindbrain developmentGO:00309021280.012
cardiac muscle cell differentiationGO:0055007690.012
t cell differentiationGO:00302171740.012
adult behaviorGO:00305341350.011
ribonucleoside biosynthetic processGO:0042455210.011
sequestering of calcium ionGO:0051208180.011
regulation of protein serine threonine kinase activityGO:00719001570.011
cellular response to growth factor stimulusGO:00713631970.011
nucleoside catabolic processGO:00091642060.011
adult locomotory behaviorGO:0008344910.011
organic hydroxy compound transportGO:0015850930.011
multicellular organism growthGO:00352641610.011
microtubule based processGO:00070172360.011
central nervous system neuron differentiationGO:00219531620.011
skeletal system morphogenesisGO:00487052030.011
divalent inorganic cation homeostasisGO:00725071380.011
glutamate biosynthetic processGO:000653720.011
negative regulation of leukocyte differentiationGO:1902106510.011
polysaccharide metabolic processGO:0005976390.011
sodium ion transportGO:0006814730.011
multicellular organismal agingGO:0010259240.011
Worm
response to extracellular stimulusGO:00099911270.011
ensheathment of neuronsGO:0007272760.011
negative regulation of organelle organizationGO:0010639900.011
regulation of kinase activityGO:00435492490.011
purine containing compound catabolic processGO:00725232130.011
olfactory bulb developmentGO:0021772300.011
regulation of t cell activationGO:00508631700.011
sensory organ morphogenesisGO:00905962420.011
rna processingGO:00063961050.011
cellular metal ion homeostasisGO:00068751510.011
wound healingGO:00420601570.011
positive regulation of programmed cell deathGO:00430682180.011
regulation of leukocyte differentiationGO:19021051590.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
cell fate commitmentGO:00451652100.011
glucose homeostasisGO:00425931280.011
development of primary sexual characteristicsGO:00451371430.011
Worm
cellularizationGO:000734910.011
negative regulation of cell developmentGO:00107211690.010
mitochondrion distributionGO:004831140.010
histone modificationGO:00165701590.010
negative regulation of lymphocyte activationGO:0051250910.010
regulation of epithelial cell proliferationGO:00506781410.010
long chain fatty acid importGO:004453920.010
synapse assemblyGO:0007416560.010
carnitine metabolic processGO:000943770.010
tube formationGO:00351481400.010
endoplasmic reticulum tubular network organizationGO:007178610.010
regulation of cytoplasmic transportGO:19036491120.010
purine nucleoside biosynthetic processGO:0042451190.010
protein maturationGO:00516041760.010
glycerophospholipid biosynthetic processGO:0046474320.010
cellular nitrogen compound catabolic processGO:00442702800.010
regulation of nucleocytoplasmic transportGO:0046822730.010
fat cell differentiationGO:00454441600.010

Pdha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.092
inherited metabolic disorderDOID:65500.061
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.031
cancerDOID:16200.023
disease of cellular proliferationDOID:1456600.023
organ system cancerDOID:005068600.021
amino acid metabolic disorderDOID:925200.016
endocrine gland cancerDOID:17000.010