Mus musculus

200 known processes

Il10

interleukin 10

(Aliases: Il-10,CSIF)

Il10 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to molecule of bacterial originGO:0071219830.998
somatic diversification of immune receptorsGO:0002200530.998
regulation of mhc class ii biosynthetic processGO:004534670.997
interleukin 6 biosynthetic processGO:0042226120.996
Mouse
defense response to other organismGO:00985421970.996
response to molecule of bacterial originGO:00022371430.996
cellular response to interleukin 18GO:007135130.996
response to lipopolysaccharideGO:00324961280.995
innate immune response activating cell surface receptor signaling pathwayGO:000222040.994
positive regulation of production of molecular mediator of immune responseGO:0002702450.994
positive regulation of b cell mediated immunityGO:0002714260.994
cellular response to lipopolysaccharideGO:0071222770.992
cellular amino acid metabolic processGO:00065201030.992
regulation of cell activationGO:00508652890.991
regulation of inflammatory response to antigenic stimulusGO:0002861210.991
negative regulation of multi organism processGO:0043901680.991
interleukin 18 productionGO:003262140.991
regulation of growth of symbiont in hostGO:0044126190.989
regulation of activated t cell proliferationGO:0046006160.988
regulation of inflammatory responseGO:00507271470.988
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.987
positive regulation of isotype switching to igg isotypesGO:004830470.986
production of molecular mediator of immune responseGO:00024401030.986
cellular response to lipidGO:00713961450.984
interleukin 18 mediated signaling pathwayGO:003565520.984
cytokine mediated signaling pathwayGO:00192211150.984
negative regulation of growth of symbiont in hostGO:0044130190.984
somatic recombination of immunoglobulin gene segmentsGO:0016447420.982
regulation of cellular ketone metabolic processGO:0010565660.982
cellular response to biotic stimulusGO:0071216920.981
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.980
cytokine productionGO:00018163190.975
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.973
immunoglobulin mediated immune responseGO:0016064690.972
dna recombinationGO:0006310920.971
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.969
positive regulation of mhc class ii biosynthetic processGO:004534840.966
cytokine metabolic processGO:0042107710.966
Mouse
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.965
positive regulation of reactive oxygen species biosynthetic processGO:190342820.962
regulation of peptidase activityGO:0052547960.962
Mouse
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.961
antibacterial peptide productionGO:000277820.961
b cell activation involved in immune responseGO:0002312500.955
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.952
cellular amine metabolic processGO:0044106440.951
lipopolysaccharide mediated signaling pathwayGO:0031663250.950
leukocyte activation involved in immune responseGO:00023661260.950
positive regulation of activated t cell proliferationGO:004210480.949
regulation of cellular amino acid metabolic processGO:000652150.949
lymphocyte activation involved in immune responseGO:0002285930.948
growth of symbiont in hostGO:0044117230.947
symbiosis encompassing mutualism through parasitismGO:0044403830.947
positive regulation of immune effector processGO:00026991070.947
somatic cell dna recombinationGO:0016444510.946
isotype switchingGO:0045190360.944
positive regulation of t cell proliferationGO:0042102520.943
negative regulation of interferon gamma productionGO:0032689180.943
reactive oxygen species metabolic processGO:0072593840.942
Mouse
b cell activationGO:00421131610.941
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.941
regulation of response to woundingGO:19030341890.939
leukocyte apoptotic processGO:0071887710.937
regulation of immunoglobulin productionGO:0002637420.937
leukocyte mediated immunityGO:00024431740.936
positive regulation of immunoglobulin mediated immune responseGO:0002891260.935
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.934
immune response activating signal transductionGO:00027571160.931
positive regulation of cellular amine metabolic processGO:003324050.925
inflammatory responseGO:00069542440.924
cell surface pattern recognition receptor signaling pathwayGO:000275220.922
regulation of isotype switchingGO:0045191220.922
regulation of innate immune responseGO:0045088910.921
cell fate commitmentGO:00451652100.919
extrinsic apoptotic signaling pathwayGO:00971911260.917
Mouse
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.916
immunoglobulin secretionGO:0048305170.913
necroptotic processGO:0070266210.913
isotype switching to ige isotypesGO:004828970.912
reactive nitrogen species metabolic processGO:200105700.908
regulation of leukocyte mediated immunityGO:00027031040.906
negative regulation of inflammatory responseGO:0050728610.903
interferon beta biosynthetic processGO:004535040.903
chronic inflammatory response to antigenic stimulusGO:000243930.901
amine metabolic processGO:0009308450.900
regulation of cellular amine metabolic processGO:0033238200.892
peptidyl tyrosine modificationGO:00182121450.887
Mouse
positive regulation of leukocyte proliferationGO:0070665730.886
regulation of cytokine production involved in immune responseGO:0002718260.885
positive regulation of interleukin 18 productionGO:003274120.885
keratinocyte migrationGO:005154630.882
positive regulation of mapk cascadeGO:00434101700.880
positive regulation of cytokine productionGO:00018191740.879
regulation of isotype switching to ige isotypesGO:004829370.879
regulation of acute inflammatory responseGO:0002673270.873
positive regulation of peptidase activityGO:0010952490.873
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.870
Mouse
cell type specific apoptotic processGO:00972852680.868
positive regulation of chronic inflammatory responseGO:000267840.868
regulation of cytokine biosynthetic processGO:0042035590.867
regulation of peptidyl tyrosine phosphorylationGO:0050730930.864
Mouse
positive regulation of response to woundingGO:1903036660.864
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.863
Mouse
interspecies interaction between organismsGO:0044419830.862
necroptotic signaling pathwayGO:009752730.861
regulation of b cell activationGO:0050864810.861
interleukin 6 productionGO:0032635580.860
Mouse
regulation of leukocyte differentiationGO:19021051590.859
t helper 1 cell lineage commitmentGO:000229620.858
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.854
myd88 dependent toll like receptor signaling pathwayGO:000275570.851
cellular response to cytokine stimulusGO:00713451890.851
adaptive immune responseGO:00022501550.851
response to interleukin 15GO:007067230.851
cytokine production involved in immune responseGO:0002367340.847
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.846
morphogenesis of a branching structureGO:00017632030.845
cellular ketone metabolic processGO:0042180840.844
cellular response to amino acid stimulusGO:0071230290.844
regulation of b cell mediated immunityGO:0002712370.841
modulation by symbiont of defense related host nitric oxide productionGO:005216310.835
progesterone metabolic processGO:004244840.833
defense response to virusGO:0051607680.830
pattern recognition receptor signaling pathwayGO:0002221470.826
neutrophil apoptotic processGO:000178130.825
signal transduction in absence of ligandGO:0038034550.819
regulation of tumor necrosis factor productionGO:0032680490.818
response to host defensesGO:005220030.817
natural killer cell mediated cytotoxicityGO:0042267290.816
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.815
lymphocyte proliferationGO:00466511640.815
regulation of interleukin 6 biosynthetic processGO:0045408110.813
immunoglobulin productionGO:0002377730.811
modification by symbiont of host morphology or physiologyGO:004400340.809
response to bacterial lipoproteinGO:003249340.807
regulation of interleukin 6 productionGO:0032675550.806
production of molecular mediator involved in inflammatory responseGO:0002532210.797
t cell differentiation involved in immune responseGO:0002292300.797
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.794
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.789
leukocyte differentiationGO:00025213420.787
innate immune response activating signal transductionGO:0002758500.786
tyrosine phosphorylation of stat proteinGO:0007260230.784
Mouse
defense response to gram negative bacteriumGO:0050829280.783
regulation of lymphocyte proliferationGO:00506701170.780
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005230210.777
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.771
negative regulation of interleukin 12 productionGO:0032695100.770
drug catabolic processGO:004273720.770
regulation of reactive oxygen species biosynthetic processGO:190342620.769
negative regulation of hydrolase activityGO:0051346710.768
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.767
negative regulation of cell proliferationGO:00082852960.767
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056390.766
Mouse
type 2 immune responseGO:0042092230.760
regulation of defense responseGO:00313472330.759
positive regulation of proteolysisGO:0045862850.759
Mouse
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.758
natural killer cell activationGO:0030101440.755
positive regulation of fever generationGO:003162260.754
fever generationGO:000166070.754
negative regulation of cytokine productionGO:0001818840.747
positive regulation of isotype switchingGO:0045830150.746
positive regulation of lymphocyte proliferationGO:0050671700.745
mast cell proliferationGO:007066240.745
negative regulation of interleukin 23 productionGO:003270710.742
regulation of map kinase activityGO:00434051200.742
peptidyl amino acid modificationGO:00181933360.738
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.738
Mouse
alpha beta t cell activation involved in immune responseGO:0002287310.736
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.734
regulation of lymphocyte differentiationGO:00456191070.733
acute inflammatory responseGO:0002526410.733
positive regulation of interleukin 12 productionGO:0032735210.732
t helper cell lineage commitmentGO:000229560.728
positive regulation of cytokine production involved in immune responseGO:0002720190.725
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.722
eosinophil degranulationGO:004330810.722
regulation of corticotropin releasing hormone secretionGO:004339720.718
positive regulation of nf kappab transcription factor activityGO:0051092300.718
negative regulation of erk1 and erk2 cascadeGO:0070373210.711
regulation of dna recombinationGO:0000018340.711
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.707
Mouse
regulation of production of molecular mediator of immune responseGO:0002700650.707
positive regulation of tumor necrosis factor productionGO:0032760300.704
regulation of t cell costimulationGO:200052320.701
defense response to gram positive bacteriumGO:0050830500.694
isotype switching to igg isotypesGO:0048291100.694
positive regulation of isotype switching to ige isotypesGO:004829540.694
toll like receptor signaling pathwayGO:0002224380.692
positive regulation of endopeptidase activityGO:0010950430.687
Mouse
positive regulation by symbiont of host immune responseGO:005255610.685
cytokine biosynthetic processGO:0042089680.684
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293300.684
alpha amino acid metabolic processGO:1901605590.679
i kappab kinase nf kappab signalingGO:0007249850.679
t cell activationGO:00421102890.675
modulation of growth of symbiont involved in interaction with hostGO:0044144190.668
chemokine metabolic processGO:0050755100.660
inflammatory cell apoptotic processGO:0006925110.658
regulation of myoblast differentiationGO:0045661290.656
regulation of natural killer cell differentiationGO:0032823110.653
regulation of interleukin 18 productionGO:003266130.650
defense response to bacteriumGO:00427421190.649
myeloid cell apoptotic processGO:0033028220.639
positive regulation of apoptotic processGO:00430652170.636
Mouse
positive regulation of type i interferon productionGO:0032481140.636
positive regulation of cell activationGO:00508671580.636
cell activation involved in immune responseGO:00022631260.635
t cell differentiationGO:00302171740.632
immune response regulating cell surface receptor signaling pathwayGO:0002768800.628
antibacterial peptide secretionGO:000277910.626
interleukin 10 secretionGO:007260840.625
regulation of alpha beta t cell proliferationGO:0046640180.625
positive regulation of translational initiationGO:004594840.622
regulation of mast cell differentiationGO:006037530.616
positive regulation of adaptive immune responseGO:0002821610.611
regulation of chronic inflammatory responseGO:000267670.611
response to defenses of other organism involved in symbiotic interactionGO:005217330.608
regulation of natural killer cell proliferationGO:003281720.607
regulation of sequence specific dna binding transcription factor activityGO:00510901060.604
myotube differentiationGO:00149021050.602
tyrosine phosphorylation of stat3 proteinGO:0042503120.599
Mouse
regulation of immunoglobulin mediated immune responseGO:0002889370.595
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.595
t helper cell differentiationGO:0042093280.592
positive regulation of cellular amino acid metabolic processGO:004576430.592
immune effector processGO:00022523210.592
positive regulation of glial cell proliferationGO:006025240.592
cellular response to organonitrogen compoundGO:00714171450.589
regulation of cysteine type endopeptidase activityGO:2000116650.587
Mouse
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.582
positive regulation of histone acetylationGO:003506680.575
negative regulation of lymphocyte activationGO:0051250910.573
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.573
response to interleukin 1GO:0070555110.572
positive regulation of lymphocyte differentiationGO:0045621610.571
negative regulation of t cell cytokine productionGO:000272510.568
regulation of secretionGO:00510462740.567
positive regulation of hematopoietic stem cell migrationGO:200047310.566
regulation of type 2 immune responseGO:0002828180.565
negative regulation of defense responseGO:0031348770.561
regulation of endopeptidase activityGO:0052548890.553
Mouse
positive regulation of innate immune responseGO:0045089800.552
mhc class ii biosynthetic processGO:004534280.552
positive regulation of defense responseGO:00313491240.551
leukocyte proliferationGO:00706611720.548
innate immune responseGO:00450871570.543
somatic diversification of immunoglobulinsGO:0016445430.540
growth of symbiont involved in interaction with hostGO:0044116230.539
negative regulation of adaptive immune responseGO:0002820250.538
response to oxygen levelsGO:0070482620.533
immune complex clearanceGO:000243420.533
regulation of protein secretionGO:0050708820.533
positive regulation of protein phosphorylationGO:00019342420.530
regulation of syncytium formation by plasma membrane fusionGO:0060142230.529
positive regulation of immunoglobulin secretionGO:005102470.526
negative regulation of chronic inflammatory responseGO:000267730.521
response to organic cyclic compoundGO:00140701980.517
regulation of organ morphogenesisGO:20000271440.516
dna metabolic processGO:00062593030.515
regulation of lymphocyte mediated immunityGO:0002706840.511
growth involved in symbiotic interactionGO:0044110230.509
chemotaxisGO:00069352470.508
antibacterial peptide biosynthetic processGO:000278020.506
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.504
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.504
regulation of mapk cascadeGO:00434082480.499
erk1 and erk2 cascadeGO:0070371770.498
detection of molecule of bacterial originGO:003249020.498
angiogenesisGO:00015252010.497
regulation of lipopolysaccharide mediated signaling pathwayGO:003166490.496
mammary gland epithelial cell proliferationGO:0033598240.495
positive regulation of protein secretionGO:0050714520.494
induction by symbiont of host immune responseGO:005255910.492
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.489
cd4 positive alpha beta t cell lineage commitmentGO:004337360.488
chemokine biosynthetic processGO:004203380.488
positive regulation of programmed cell deathGO:00430682180.487
Mouse
alpha beta t cell lineage commitmentGO:000236370.484
cellular response to bacterial lipoproteinGO:007122030.484
eosinophil activationGO:004330710.481
urogenital system developmentGO:00016552610.477
positive regulation of immunological synapse formationGO:200052210.477
negative regulation of interleukin 5 productionGO:003271440.477
regulation of lymphocyte activationGO:00512492400.475
b cell mediated immunityGO:0019724710.472
positive regulation of interleukin 6 productionGO:0032755370.471
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.461
epithelial cell proliferationGO:00506731740.461
negative regulation of interleukin 5 secretionGO:200066310.460
response to hostGO:007513630.459
placenta developmentGO:00018901400.457
positive regulation of cell deathGO:00109422240.455
Mouse
regulation of leukocyte proliferationGO:00706631210.455
immune response regulating signaling pathwayGO:00027641250.455
blood vessel morphogenesisGO:00485142850.454
morphogenesis of a branching epitheliumGO:00611381930.449
positive regulation of leukocyte mediated immunityGO:0002705700.447
regulation of adaptive immune responseGO:0002819900.444
corticotropin releasing hormone secretionGO:004339620.441
regulation of tumor necrosis factor biosynthetic processGO:0042534100.440
reactive oxygen species biosynthetic processGO:190340980.437
regulation of jak stat cascadeGO:0046425340.437
Mouse
branching involved in salivary gland morphogenesisGO:0060445260.437
dephosphorylationGO:00163111290.434
positive regulation of activation of membrane attack complexGO:000197020.432
exogenous drug catabolic processGO:004273810.430
positive regulation of map kinase activityGO:0043406840.427
positive regulation of apoptotic signaling pathwayGO:2001235950.425
Mouse
negative regulation of cellular component organizationGO:00511291940.423
positive regulation of immunoglobulin productionGO:0002639280.422
muscle cell developmentGO:00550011330.419
positive regulation of dna recombinationGO:0045911170.416
negative regulation of response to woundingGO:1903035770.413
positive regulation of interferon gamma productionGO:0032729390.412
regulation of b cell proliferationGO:0030888390.412
acute phase responseGO:0006953100.410
positive regulation of jak stat cascadeGO:0046427220.407
positive regulation of reactive oxygen species metabolic processGO:2000379110.407
regulation of histone acetylationGO:0035065190.407
t cell selectionGO:0045058340.400
modulation by symbiont of host immune responseGO:005255310.398
syncytium formation by plasma membrane fusionGO:0000768420.396
organ or tissue specific immune responseGO:0002251130.396
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.391
salivary gland developmentGO:0007431370.390
negative regulation of chemokine biosynthetic processGO:004507920.387
negative regulation of protein processingGO:0010955790.383
Mouse
regulation of chemokine productionGO:0032642300.378
wnt signaling pathwayGO:00160551880.378
leukocyte homeostasisGO:0001776790.377
modulation by organism of immune response of other organism involved in symbiotic interactionGO:005255210.376
epidermis developmentGO:00085441870.372
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.371
Mouse
positive regulation of secretionGO:00510471300.368
positive regulation of b cell proliferationGO:0030890240.365
natural killer cell mediated immunityGO:0002228290.363
protein oligomerizationGO:0051259670.363
heat generationGO:0031649130.362
positive regulation by organism of immune response of other organism involved in symbiotic interactionGO:005255510.361
lymphocyte homeostasisGO:0002260640.360
response to acid chemicalGO:00011011110.357
defense response to protozoanGO:0042832250.356
protein maturationGO:00516041760.352
Mouse
cellular response to bacterial lipopeptideGO:007122130.350
negative regulation of immune system processGO:00026832090.348
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.346
negative regulation of macrophage apoptotic processGO:200011030.343
negative regulation of apoptotic signaling pathwayGO:20012341040.342
Mouse
positive regulation of histone modificationGO:0031058280.341
positive regulation of monocyte chemotaxisGO:009002620.341
positive regulation of chemokine productionGO:0032722220.340
negative regulation of endopeptidase activityGO:0010951440.340
Mouse
regulation of mast cell proliferationGO:007066640.339
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.334
regulation of epithelial cell proliferationGO:00506781410.334
eosinophil activation involved in immune responseGO:000227810.333
positive regulation of lymphocyte mediated immunityGO:0002708620.332
cation homeostasisGO:00550802120.329
positive regulation of protein transportGO:0051222930.328
response to iron ionGO:001003940.328
activation of mapk activity involved in innate immune responseGO:003541920.322
anatomical structure homeostasisGO:00602491450.319
regulation of establishment of protein localizationGO:00702011810.317
regulation of angiogenesisGO:0045765810.317
regulation of chemokine biosynthetic processGO:004507380.314
mapk cascadeGO:00001652810.314
regulation of protein localizationGO:00328802310.313
muscle cell proliferationGO:0033002520.312
natural killer cell proliferationGO:000178730.311
b cell proliferationGO:0042100530.309
cellular response to peptideGO:1901653920.308
positive regulation of chemokine biosynthetic processGO:004508060.307
lymphocyte apoptotic processGO:0070227540.306
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.306
t cell activation involved in immune responseGO:0002286430.305
regulation of defense response to bacteriumGO:190042430.304
organic hydroxy compound metabolic processGO:19016152030.303
drug metabolic processGO:001714440.302
response to hypoxiaGO:0001666580.299
regulation of cell migrationGO:00303342190.299
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.296
t cell proliferationGO:00420981200.295
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587260.294
interleukin 27 mediated signaling pathwayGO:007010610.293
modification of morphology or physiology of other organismGO:0035821180.289
muscle cell differentiationGO:00426922610.284
regulation of myotube differentiationGO:0010830620.282
humoral immune responseGO:0006959570.282
positive regulation of chemotaxisGO:0050921380.281
regulation of cytokine productionGO:00018172660.279
positive regulation of t cell activationGO:00508701010.278
antibiotic transportGO:004289110.277
positive regulation of t cell costimulationGO:200052520.275
mammary gland lobule developmentGO:0061377220.275
lymphocyte differentiationGO:00300982420.274
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.274
protein kinase b signalingGO:0043491740.272
stem cell developmentGO:00488642190.271
glucagon secretionGO:007009130.271
positive regulation of protein modification processGO:00314012990.264
positive regulation of t cell receptor signaling pathwayGO:005086240.264
modulation by symbiont of host defense responseGO:005203110.257
positive regulation of inflammatory responseGO:0050729470.255
alpha beta t cell differentiationGO:0046632690.255
smad protein complex assemblyGO:000718310.254
positive regulation of acute inflammatory responseGO:0002675160.254
regulation of myeloid leukocyte differentiationGO:0002761580.253
cd4 positive alpha beta t cell activationGO:0035710450.252
myeloid cell homeostasisGO:00022621140.251
fatty acid metabolic processGO:00066311210.246
negative regulation of lymphocyte proliferationGO:0050672450.246
interferon gamma productionGO:0032609670.245
response to inorganic substanceGO:0010035960.244
activation of innate immune responseGO:0002218560.243
positive regulation of muscle cell differentiationGO:0051149390.242
t helper 1 type immune responseGO:0042088250.242
regulation of isotype switching to igg isotypesGO:0048302100.240
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.240
Mouse
glutamine family amino acid catabolic processGO:000906550.239
t cell receptor signaling pathwayGO:0050852460.239
alpha amino acid catabolic processGO:1901606180.239
negative regulation of type 2 immune responseGO:000282980.238
cell cell recognitionGO:0009988440.237
inflammatory response to woundingGO:009059440.235
response to granulocyte macrophage colony stimulating factorGO:009701230.235
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.235
regulation of reactive oxygen species metabolic processGO:2000377400.234
branching involved in mammary gland duct morphogenesisGO:0060444270.233
response to interferon gammaGO:0034341340.232
response to amino acidGO:0043200370.231
regulation of peptidyl serine phosphorylationGO:0033135390.228
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.226
regulation of interferon gamma productionGO:0032649570.226
zymogen activationGO:0031638410.224
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.222
regulation of interferon beta biosynthetic processGO:004535740.221
negative regulation of myeloid cell differentiationGO:0045638380.220
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005226310.220
nitrogen compound transportGO:00717052710.218
response to interleukin 4GO:0070670230.218
cellular response to interferon gammaGO:0071346250.217
leukocyte migrationGO:00509001240.215
regulation of proteolysisGO:00301621640.214
Mouse
histone acetylationGO:0016573410.210
granulocyte migrationGO:0097530430.210
negative regulation of homeostatic processGO:0032845710.208
regulation of muscle tissue developmentGO:1901861970.208
tyrosine phosphorylation of stat1 proteinGO:004250830.207
positive regulation of interferon alpha productionGO:003272740.206
response to host immune responseGO:005257230.206
positive regulation of natural killer cell mediated immunityGO:0002717160.205
activation induced cell death of t cellsGO:0006924100.205
response to growth factorGO:00708481980.205
regulation of immunoglobulin secretionGO:0051023120.204
regulation of striated muscle cell differentiationGO:0051153810.204
regulation of myeloid dendritic cell activationGO:003088550.203
negative regulation of glycolytic processGO:004582040.203
regulation of secretion by cellGO:19035302490.202
positive regulation of protein import into nucleusGO:0042307260.202
regulation of dendritic cell chemotaxisGO:200050810.202
regulation of t cell differentiationGO:0045580830.201
positive regulation of gamma delta t cell differentiationGO:004558860.199
vascular endothelial growth factor productionGO:0010573130.199
antigen receptor mediated signaling pathwayGO:0050851640.198
digestive tract developmentGO:00485651900.197
chromatin organizationGO:00063252060.197
necrotic cell deathGO:0070265300.197
regulation of toll like receptor 2 signaling pathwayGO:003413530.197
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.196
regulation of protein transportGO:00512231630.196
negative regulation of chemokine productionGO:003268240.195
protein processingGO:00164851630.195
Mouse
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.195
regulation of vitamin metabolic processGO:003065630.195
neuron apoptotic processGO:00514021420.194
regulation of myeloid cell differentiationGO:0045637960.194
regulation of osteoclast differentiationGO:0045670360.193
regulation of natural killer cell mediated immunityGO:0002715190.192
positive regulation of synaptic plasticityGO:003191540.190
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.190
positive regulation of antibacterial peptide biosynthetic processGO:000696310.188
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287620.188
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.186
activation of mapk activityGO:0000187590.183
intracellular receptor signaling pathwayGO:0030522740.183

Il10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inflammatory bowel diseaseDOID:005058900.674
disease of anatomical entityDOID:700.674
gastrointestinal system diseaseDOID:7700.674
intestinal diseaseDOID:529500.674
disease of cellular proliferationDOID:1456600.316
immune system diseaseDOID:291400.232
hypersensitivity reaction diseaseDOID:006005600.232
bone remodeling diseaseDOID:008000500.219
bone diseaseDOID:008000100.219
musculoskeletal system diseaseDOID:1700.219
connective tissue diseaseDOID:6500.219
cancerDOID:16200.218