Mus musculus

0 known processes

Helz

helicase with zinc finger domain

(Aliases: AI851979,3110078M01Rik,KIAA0054,DRHC,9430093I07Rik,9630002H22Rik)

Helz biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063252060.254
positive regulation of dna templated transcription elongationGO:003278620.231
histone acetylationGO:0016573410.174
chromatin modificationGO:00165681870.130
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.129
cellular response to dna damage stimulusGO:00069742070.122
covalent chromatin modificationGO:00165691630.113
regionalizationGO:00030023370.098
cellular macromolecule catabolic processGO:00442652060.078
glycosyl compound catabolic processGO:19016582060.073
purine ribonucleoside triphosphate metabolic processGO:00092052200.072
dna metabolic processGO:00062593030.067
peptidyl lysine modificationGO:0018205770.062
nucleoside phosphate metabolic processGO:00067533380.059
methylationGO:00322591340.058
purine ribonucleoside metabolic processGO:00461282410.058
histone h3 acetylationGO:0043966140.058
heterocycle catabolic processGO:00467002800.054
nucleotide metabolic processGO:00091173320.051
leukocyte differentiationGO:00025213420.049
compound eye developmentGO:004874910.045
wnt signaling pathwayGO:00160551880.044
purine nucleoside triphosphate metabolic processGO:00091442260.043
histone modificationGO:00165701590.042
cellular amino acid metabolic processGO:00065201030.042
rho protein signal transductionGO:0007266320.042
male gamete generationGO:00482322850.041
lateral inhibitionGO:004633110.041
histone h4 k12 acetylationGO:004398320.040
regulation of histone methylationGO:0031060300.039
stem cell maintenanceGO:00198271300.039
purine ribonucleoside triphosphate catabolic processGO:00092071990.038
gonad developmentGO:00084061410.038
purine nucleoside metabolic processGO:00422782410.037
gene silencing by mirnaGO:0035195100.037
macromolecule catabolic processGO:00090572810.037
ribonucleotide catabolic processGO:00092612080.036
ribose phosphate metabolic processGO:00196932910.035
purine ribonucleotide metabolic processGO:00091502900.035
regulation of histone modificationGO:0031056560.035
purine containing compound catabolic processGO:00725232130.035
histone lysine methylationGO:0034968500.034
nucleobase containing small molecule metabolic processGO:00550863520.034
nucleotide catabolic processGO:00091662170.034
organic cyclic compound catabolic processGO:19013612950.034
ribonucleoside triphosphate catabolic processGO:00092031990.034
protein acylationGO:0043543640.032
posttranscriptional gene silencingGO:0016441100.032
nucleoside metabolic processGO:00091162460.031
somatic stem cell maintenanceGO:0035019470.031
spermatogenesisGO:00072832840.030
male meiosis iGO:0007141160.030
stem cell differentiationGO:00488632680.030
internal peptidyl lysine acetylationGO:0018393420.030
regulation of organelle organizationGO:00330432890.030
positive regulation of cellular amine metabolic processGO:003324050.030
hypermethylation of cpg islandGO:004402730.030
purine containing compound metabolic processGO:00725213110.030
posttranscriptional regulation of gene expressionGO:00106081550.029
regulation of dna templated transcription elongationGO:0032784100.029
nucleoside triphosphate metabolic processGO:00091412300.029
blastocyst developmentGO:0001824800.029
atp metabolic processGO:0046034750.029
ribonucleoside metabolic processGO:00091192450.029
ribonucleoside monophosphate metabolic processGO:0009161800.028
internal protein amino acid acetylationGO:0006475420.028
glycosyl compound metabolic processGO:19016572460.028
cellular nitrogen compound catabolic processGO:00442702800.028
purine ribonucleotide catabolic processGO:00091542080.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
organonitrogen compound catabolic processGO:19015652640.028
neural precursor cell proliferationGO:00613511210.027
regulation of cell cycle processGO:00105641600.027
regulation of transcription during meiosisGO:005103710.027
positive regulation of cell deathGO:00109422240.027
cellular ketone metabolic processGO:0042180840.027
regulation of synaptic growth at neuromuscular junctionGO:000858240.027
regulation of response to dna damage stimulusGO:2001020340.027
amine metabolic processGO:0009308450.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.026
peptidyl lysine methylationGO:0018022290.026
peptidyl amino acid modificationGO:00181933360.025
blood vessel morphogenesisGO:00485142850.025
ribonucleotide metabolic processGO:00092592910.025
purine ribonucleoside catabolic processGO:00461302050.024
protein modification by small protein conjugation or removalGO:00706472070.023
male meiosisGO:0007140370.023
mrna metabolic processGO:0016071840.023
protein dna complex subunit organizationGO:0071824280.023
regulation of cellular amino acid metabolic processGO:000652150.023
digestive tract morphogenesisGO:00485461470.023
negative regulation of synapse assemblyGO:005196430.023
positive regulation of cellular catabolic processGO:00313311480.023
dna methylationGO:0006306430.023
aromatic compound catabolic processGO:00194392860.023
regulation of nucleotide metabolic processGO:00061401690.023
histone methylationGO:0016571710.023
organophosphate catabolic processGO:00464342320.022
rna interferenceGO:001624620.022
lung developmentGO:00303241640.022
muscle tissue developmentGO:00605373080.022
regulation of chromatin organizationGO:1902275570.022
negative regulation of cellular protein metabolic processGO:00322692470.021
macromolecule methylationGO:00434141200.021
negative regulation of cell developmentGO:00107211690.021
dna repairGO:00062811070.021
negative regulation of cell proliferationGO:00082852960.021
endocytosisGO:00068971680.020
stem cell developmentGO:00488642190.020
notch signaling pathwayGO:0007219710.020
germ cell developmentGO:00072811850.020
regulation of cellular catabolic processGO:00313292420.020
negative regulation of cellular component organizationGO:00511291940.020
purine nucleoside catabolic processGO:00061522050.019
rna processingGO:00063961050.019
regulation of cell cycleGO:00517262810.019
Mouse
myeloid cell differentiationGO:00300992330.019
rhythmic processGO:00485111740.019
small gtpase mediated signal transductionGO:0007264970.019
embryonic organ morphogenesisGO:00485622760.019
positive regulation of apoptotic processGO:00430652170.019
purine nucleotide catabolic processGO:00061952110.019
protein catabolic processGO:00301632210.019
purine nucleoside monophosphate metabolic processGO:0009126810.019
cellular amine metabolic processGO:0044106440.019
regulation of cellular response to stressGO:00801351590.019
neuroblast fate commitmentGO:001401710.018
segmentationGO:0035282930.018
mitotic cell cycle processGO:19030471590.018
regulation of neuron differentiationGO:00456642810.018
nucleoside phosphate catabolic processGO:19012922220.018
protein alkylationGO:0008213810.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
regulation of neuron deathGO:19012141340.018
cellular protein catabolic processGO:00442571550.018
ribonucleoside monophosphate catabolic processGO:0009158570.018
nucleoside catabolic processGO:00091642060.018
neuroblast differentiationGO:001401620.018
positive regulation of nucleoside metabolic processGO:0045979910.018
regulation of defense responseGO:00313472330.018
canonical wnt signaling pathwayGO:00600701300.018
purine nucleoside monophosphate catabolic processGO:0009128580.018
regulation of mitotic cell cycleGO:00073461260.018
negative regulation of protein metabolic processGO:00512482820.018
regulation of cellular amine metabolic processGO:0033238200.018
sensory perceptionGO:00076002450.017
regulation of cell projection organizationGO:00313442060.017
histone h4 acetylationGO:0043967100.017
nuclear divisionGO:00002801580.017
purine nucleoside triphosphate catabolic processGO:00091462030.017
striated muscle tissue developmentGO:00147062930.017
peptidyl lysine trimethylationGO:0018023120.017
axon guidanceGO:00074111410.017
telencephalon developmentGO:00215371860.017
chemotaxisGO:00069352470.017
histone h3 k4 trimethylationGO:008018250.017
peptidyl lysine acetylationGO:0018394450.017
cell cycle checkpointGO:0000075470.017
histone h4 k16 acetylationGO:004398430.017
neuron projection guidanceGO:00974851410.017
microtubule based processGO:00070172360.016
organophosphate biosynthetic processGO:00904071220.016
gene silencing by rnaGO:0031047190.016
purine nucleotide metabolic processGO:00061633020.016
alpha beta t cell activationGO:0046631910.016
regulation of purine nucleotide catabolic processGO:00331211220.016
protein methylationGO:0006479810.016
histone deubiquitinationGO:001657820.016
body morphogenesisGO:0010171450.016
gene silencingGO:0016458380.016
regulation of gtp catabolic processGO:00331241130.016
positive regulation of programmed cell deathGO:00430682180.016
mesenchyme developmentGO:00604851520.016
organelle localizationGO:00516401790.016
carbohydrate derivative catabolic processGO:19011362310.016
protein modification by small protein conjugationGO:00324461870.016
renal system developmentGO:00720012250.016
t cell activationGO:00421102890.015
carbohydrate metabolic processGO:00059752300.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.015
lymphocyte differentiationGO:00300982420.015
neuromuscular processGO:0050905990.015
forebrain developmentGO:00309003020.015
heart morphogenesisGO:00030071780.015
sensory perception of mechanical stimulusGO:00509541070.015
morphogenesis of embryonic epitheliumGO:00163311590.015
locomotory behaviorGO:00076261950.015
nucleoside monophosphate metabolic processGO:0009123850.015
digestive tract developmentGO:00485651900.015
regulation of cellular ketone metabolic processGO:0010565660.015
embryonic placenta developmentGO:0001892980.014
transcription elongation from rna polymerase ii promoterGO:000636890.014
axonogenesisGO:00074092740.014
camera type eye developmentGO:00430102660.014
ear developmentGO:00435832000.014
chromatin remodelingGO:0006338320.014
regulation of nucleoside metabolic processGO:00091181300.014
skeletal system developmentGO:00015013560.014
cell recognitionGO:0008037830.014
cell type specific apoptotic processGO:00972852680.014
maintenance of locationGO:0051235890.014
positive regulation of histone h3 k9 methylationGO:005157440.014
microtubule cytoskeleton organizationGO:00002261570.014
stem cell fate specificationGO:004886630.014
anatomical structure homeostasisGO:00602491450.014
asymmetric stem cell divisionGO:009872230.013
positive regulation of nervous system developmentGO:00519622210.013
digestive system developmentGO:00551232000.013
negative regulation of organelle organizationGO:0010639900.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
organelle assemblyGO:00709251770.013
skeletal muscle organ developmentGO:00605381630.013
intracellular receptor signaling pathwayGO:0030522740.013
cytokine productionGO:00018163190.013
respiratory tube developmentGO:00303231670.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
cytoplasmic transportGO:00164822340.013
regulation of mitotic cell cycle phase transitionGO:1901990730.013
neuronal action potentialGO:0019228540.013
gastrulationGO:00073691160.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
modification dependent macromolecule catabolic processGO:00436321330.013
posttranscriptional gene silencing by rnaGO:0035194100.013
mitotic cell cycleGO:00002781950.013
regulation of chromosome organizationGO:0033044830.013
skeletal muscle cell differentiationGO:0035914660.012
b cell activationGO:00421131610.012
development of primary sexual characteristicsGO:00451371430.012
neural tube formationGO:00018411080.012
ribonucleoside catabolic processGO:00424542060.012
regulation of response to drugGO:200102320.012
dna modificationGO:0006304500.012
epithelial cell developmentGO:00020641590.012
artery developmentGO:0060840530.012
pharynx developmentGO:006046510.012
ras protein signal transductionGO:0007265770.012
regulation of anatomical structure sizeGO:00900661780.012
lipid localizationGO:00108761260.012
mesenchymal cell differentiationGO:00487621070.012
nucleoside triphosphate catabolic processGO:00091432050.012
response to growth factorGO:00708481980.012
t cell differentiationGO:00302171740.012
female sex differentiationGO:0046660840.012
morphogenesis of a branching structureGO:00017632030.012
actin cytoskeleton organizationGO:00300362200.012
histone h3 k4 methylationGO:0051568230.012
positive regulation of protein modification processGO:00314012990.012
regulation of wnt signaling pathwayGO:00301111230.012
regulation of cell motilityGO:20001452360.012
proteasomal protein catabolic processGO:0010498980.012
negative regulation of cell cycleGO:00457861230.012
Mouse
regulation of rho gtpase activityGO:0032319580.012
mrna catabolic processGO:0006402220.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
regulation of membrane potentialGO:00423911920.011
neuron apoptotic processGO:00514021420.011
positive regulation of protein phosphorylationGO:00019342420.011
somite developmentGO:0061053810.011
myosin filament assemblyGO:003103420.011
myeloid cell homeostasisGO:00022621140.011
regulation of notch signaling pathwayGO:0008593350.011
neuromuscular process controlling balanceGO:0050885590.011
cellular lipid metabolic processGO:00442553230.011
negative regulation of cell cycle processGO:0010948690.011
endodermal cell fate specificationGO:000171440.011
positive regulation of neuron differentiationGO:00456661410.011
cell fate commitmentGO:00451652100.011
regulation of cellular component sizeGO:00325351210.011
regulation of asymmetric cell divisionGO:000978640.011
sensory system developmentGO:004888030.011
positive regulation of rho gtpase activityGO:0032321410.011
sensory organ morphogenesisGO:00905962420.011
urogenital system developmentGO:00016552610.011
female gamete generationGO:0007292740.011
negative regulation of nervous system developmentGO:00519611560.011
morphogenesis of a branching epitheliumGO:00611381930.011
regulation of neuron apoptotic processGO:00435231220.011
organonitrogen compound biosynthetic processGO:19015661920.011
histone h3 k14 acetylationGO:004415430.011
regulation of neuron projection developmentGO:00109751690.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
glucose homeostasisGO:00425931280.011
vagus nerve developmentGO:002156430.011
regulation of bmp signaling pathwayGO:0030510600.010
positive regulation of nucleotide metabolic processGO:00459811140.010
regulation of purine nucleotide metabolic processGO:19005421690.010
cellular response to growth factor stimulusGO:00713631970.010
dna templated transcription elongationGO:0006354130.010
neuron deathGO:00709971540.010
mitotic cytokinesisGO:000028140.010
carbohydrate homeostasisGO:00335001280.010
regulation of chromatin silencingGO:003193520.010
placenta developmentGO:00018901400.010
myotube differentiationGO:00149021050.010
protein ubiquitinationGO:00165671710.010
nucleocytoplasmic transportGO:00069131390.010
negative regulation of intracellular signal transductionGO:19025321670.010

Helz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.019
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
disease of anatomical entityDOID:700.015
connective tissue diseaseDOID:6500.015
musculoskeletal system diseaseDOID:1700.015