IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Dsc1

desmocollin 1

(Aliases: MGC129348,Dsc1a,Dsc1b)

Entrez: 13505
Ensembl: ENSMUSG00000044322
UniProtKB: P55849
UniProtKB: Q32ME9
UniProtKB: Q2VPA9

Process Predictions
Disease Predictions

Dsc1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
sa node cell action potential	GO:0086015	4	0.385
cell communication by electrical coupling involved in cardiac conduction	GO:0086064	2	0.385
av node cell to bundle of his cell communication	GO:0086067	2	0.383
sa node cell to atrial cardiac muscle cell signalling	GO:0086018	4	0.305
striated muscle contraction	GO:0006941	45	0.285
ion transmembrane transport	GO:0034220	361	0.265
milk ejection	GO:0060156	1	0.259
regulation of action potential	GO:0098900	4	0.255
amine metabolic process	GO:0009308	45	0.228
regulation of defense response	GO:0031347	233	0.216
atrial ventricular junction remodeling	GO:0003294	2	0.211
cell communication by chemical coupling	GO:0010643	2	0.202
sensory perception	GO:0007600	245	0.198	Mouse
muscle system process	GO:0003012	141	0.174
foramen ovale closure	GO:0035922	1	0.172
regulation of renin secretion into blood stream	GO:1900133	4	0.172
cardiac muscle cell contraction	GO:0086003	7	0.165
regulation of membrane depolarization during action potential	GO:0098902	1	0.156
inflammatory response	GO:0006954	244	0.146
synaptic transmission	GO:0007268	329	0.143
regulation of secretion	GO:0051046	274	0.132
regulation of response to wounding	GO:1903034	189	0.131
muscle contraction	GO:0006936	101	0.131
transmembrane transport	GO:0055085	412	0.127	Mouse
wnt signaling pathway	GO:0016055	188	0.125	Mouse
cellular amine metabolic process	GO:0044106	44	0.124
camera type eye development	GO:0043010	266	0.124
embryonic placenta development	GO:0001892	98	0.117
regulation of muscle contraction	GO:0006937	49	0.107
ventricular cardiac muscle cell action potential	GO:0086005	4	0.106
actin filament based movement	GO:0030048	23	0.103
regulation of body fluid levels	GO:0050878	162	0.103	Mouse
regulation of cell activation	GO:0050865	289	0.102
cellular lipid metabolic process	GO:0044255	323	0.099
response to radiation	GO:0009314	165	0.098
stem cell development	GO:0048864	219	0.095	Mouse
muscle tissue development	GO:0060537	308	0.090
small gtpase mediated signal transduction	GO:0007264	97	0.087
regulation of membrane repolarization	GO:0060306	7	0.086
fatty acid metabolic process	GO:0006631	121	0.086
actin cytoskeleton organization	GO:0030036	220	0.080
regulation of inflammatory response	GO:0050727	147	0.074
intermediate filament based process	GO:0045103	27	0.072
protein maturation	GO:0051604	176	0.071
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.071
actin mediated cell contraction	GO:0070252	15	0.071
regulation of ion transmembrane transport	GO:0034765	119	0.070
embryonic organ morphogenesis	GO:0048562	276	0.070
ear development	GO:0043583	200	0.070	Mouse
protein processing	GO:0016485	163	0.069
regulation of blood pressure	GO:0008217	93	0.067
cation transmembrane transport	GO:0098655	266	0.066
regulation of system process	GO:0044057	200	0.065
regulation of secretion by cell	GO:1903530	249	0.065
membrane depolarization	GO:0051899	64	0.064
regulation of muscle system process	GO:0090257	80	0.064
regulation of ventricular cardiac muscle cell membrane depolarization	GO:0060373	2	0.063
sensory perception of sound	GO:0007605	97	0.063	Mouse
regulation of membrane depolarization during cardiac muscle cell action potential	GO:1900825	1	0.063
epithelial cell proliferation	GO:0050673	174	0.063	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.062
cell communication by electrical coupling	GO:0010644	4	0.060
regulation of protein transport	GO:0051223	163	0.060
regulation of hydrolase activity	GO:0051336	246	0.058	Mouse
organonitrogen compound biosynthetic process	GO:1901566	192	0.058
regulation of establishment of protein localization	GO:0070201	181	0.058
cell type specific apoptotic process	GO:0097285	268	0.057
regulation of cellular amine metabolic process	GO:0033238	20	0.056
satellite cell activation involved in skeletal muscle regeneration	GO:0014901	3	0.055
membrane organization	GO:0061024	245	0.055	Mouse
lens development in camera type eye	GO:0002088	62	0.054
morphogenesis of a branching structure	GO:0001763	203	0.053	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.053
septum primum development	GO:0003284	4	0.053
regulation of satellite cell activation involved in skeletal muscle regeneration	GO:0014717	3	0.052
heart process	GO:0003015	94	0.052
carboxylic acid transport	GO:0046942	100	0.052
intermediate filament organization	GO:0045109	15	0.051
regulation of actin filament based process	GO:0032970	99	0.050
response to molecule of bacterial origin	GO:0002237	143	0.050
intermediate filament cytoskeleton organization	GO:0045104	26	0.049
response to lipopolysaccharide	GO:0032496	128	0.049
limb development	GO:0060173	166	0.049
heterocycle catabolic process	GO:0046700	280	0.049
positive regulation of programmed cell death	GO:0043068	218	0.049
urogenital system development	GO:0001655	261	0.048
bone development	GO:0060348	120	0.048
ear morphogenesis	GO:0042471	118	0.048
organophosphate catabolic process	GO:0046434	232	0.047
organic anion transport	GO:0015711	137	0.046
anion transport	GO:0006820	177	0.045
regulation of cardiac muscle cell action potential	GO:0098901	1	0.045
multicellular organismal water homeostasis	GO:0050891	23	0.045	Mouse
regulation of striated muscle contraction	GO:0006942	25	0.045
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.044
blood circulation	GO:0008015	195	0.044
placenta development	GO:0001890	140	0.043
regulation of organelle organization	GO:0033043	289	0.043
purine nucleoside catabolic process	GO:0006152	205	0.043
cellular homeostasis	GO:0019725	240	0.043
regulation of water loss via skin	GO:0033561	16	0.042	Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.042
ribonucleotide metabolic process	GO:0009259	291	0.042
regulation of keratinocyte differentiation	GO:0045616	11	0.041
regulation of heart rate	GO:0002027	36	0.041
regulation of endopeptidase activity	GO:0052548	89	0.040	Mouse
epithelial tube morphogenesis	GO:0060562	303	0.040
response to inorganic substance	GO:0010035	96	0.040
axonogenesis	GO:0007409	274	0.040	Mouse
aromatic compound catabolic process	GO:0019439	286	0.040
cellular nitrogen compound catabolic process	GO:0044270	280	0.039
organic cyclic compound catabolic process	GO:1901361	295	0.039
cardiac muscle contraction	GO:0060048	32	0.039
circulatory system process	GO:0003013	197	0.039
cell maturation	GO:0048469	127	0.038
nucleoside phosphate catabolic process	GO:1901292	222	0.038
regulation of membrane potential	GO:0042391	192	0.038
cation transport	GO:0006812	399	0.038
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.037
regulation of peptidase activity	GO:0052547	96	0.037	Mouse
lymphocyte proliferation	GO:0046651	164	0.037
carboxylic acid biosynthetic process	GO:0046394	86	0.037
sensory perception of smell	GO:0007608	26	0.037
water homeostasis	GO:0030104	27	0.037	Mouse
regulation of vesicle mediated transport	GO:0060627	139	0.037
negative regulation of molecular function	GO:0044092	258	0.036
nucleotide catabolic process	GO:0009166	217	0.036
nitrogen compound transport	GO:0071705	271	0.035	Mouse
regulation of protein processing	GO:0070613	96	0.035
actin filament organization	GO:0007015	113	0.035
cell cell recognition	GO:0009988	44	0.035
negative regulation of cellular protein metabolic process	GO:0032269	247	0.035
sensory perception of pain	GO:0019233	47	0.034
negative regulation of protein metabolic process	GO:0051248	282	0.034
cellular ion homeostasis	GO:0006873	165	0.034
response to extracellular stimulus	GO:0009991	127	0.033	Mouse
positive regulation of secretion	GO:0051047	130	0.033
negative regulation of endopeptidase activity	GO:0010951	44	0.033
reactive oxygen species metabolic process	GO:0072593	84	0.032
heart contraction	GO:0060047	93	0.032
nucleotide metabolic process	GO:0009117	332	0.032
developmental maturation	GO:0021700	193	0.032
blood vessel morphogenesis	GO:0048514	285	0.032	Mouse
regulation of systemic arterial blood pressure	GO:0003073	61	0.032
regulation of cell projection organization	GO:0031344	206	0.032	Mouse
protein secretion	GO:0009306	111	0.032
cellular ketone metabolic process	GO:0042180	84	0.031
positive regulation of defense response	GO:0031349	124	0.031
cellular amino acid metabolic process	GO:0006520	103	0.031
regulation of proteolysis	GO:0030162	164	0.031	Mouse
sensory perception of light stimulus	GO:0050953	54	0.031
male gamete generation	GO:0048232	285	0.031
keratinocyte differentiation	GO:0030216	48	0.031
neuron apoptotic process	GO:0051402	142	0.030
nucleoside phosphate metabolic process	GO:0006753	338	0.030
regulation of protein localization	GO:0032880	231	0.030	Mouse
regulation of kinase activity	GO:0043549	249	0.030
purine nucleoside metabolic process	GO:0042278	241	0.030
regulation of hormone levels	GO:0010817	211	0.030
neuromuscular process	GO:0050905	99	0.030
negative regulation of cell development	GO:0010721	169	0.029
glycosyl compound catabolic process	GO:1901658	206	0.029
sensory perception of chemical stimulus	GO:0007606	51	0.029
regulation of actin cytoskeleton organization	GO:0032956	84	0.029
cellular response to organic cyclic compound	GO:0071407	87	0.029
purine ribonucleotide metabolic process	GO:0009150	290	0.029
sensory organ morphogenesis	GO:0090596	242	0.028
embryonic heart tube morphogenesis	GO:0003143	51	0.028
organic hydroxy compound metabolic process	GO:1901615	203	0.028
purine ribonucleotide catabolic process	GO:0009154	208	0.028
primary neural tube formation	GO:0014020	95	0.028
purine nucleotide metabolic process	GO:0006163	302	0.028
regulation of endocytosis	GO:0030100	69	0.028
small molecule biosynthetic process	GO:0044283	132	0.028
hepatocyte apoptotic process	GO:0097284	11	0.028
cellular response to organonitrogen compound	GO:0071417	145	0.027	Mouse
regulation of membrane depolarization	GO:0003254	11	0.027
leukocyte proliferation	GO:0070661	172	0.027
ribonucleoside catabolic process	GO:0042454	206	0.027
cellular response to cytokine stimulus	GO:0071345	189	0.027
positive regulation of cell cycle	GO:0045787	92	0.027
learning	GO:0007612	98	0.027
cytokine mediated signaling pathway	GO:0019221	115	0.027
phenol containing compound metabolic process	GO:0018958	60	0.027
skin development	GO:0043588	220	0.027
cardiac septum development	GO:0003279	59	0.026
transmission of nerve impulse	GO:0019226	76	0.026
purine containing compound metabolic process	GO:0072521	311	0.026
regulation of cell growth	GO:0001558	91	0.026	Mouse
ras protein signal transduction	GO:0007265	77	0.026
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.026
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.026	Mouse
epithelial cell development	GO:0002064	159	0.026	Mouse
regulation of lipid metabolic process	GO:0019216	118	0.026
skeletal system development	GO:0001501	356	0.025
kidney development	GO:0001822	213	0.025
embryonic limb morphogenesis	GO:0030326	126	0.025
regulation of blood circulation	GO:1903522	93	0.025
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.024	Mouse
cognition	GO:0050890	149	0.024
labyrinthine layer development	GO:0060711	49	0.024
cell recognition	GO:0008037	83	0.024
mapk cascade	GO:0000165	281	0.024	Mouse
cellular response to lipopolysaccharide	GO:0071222	77	0.023
regulation of cardiac muscle cell contraction	GO:0086004	11	0.023
glycosyl compound metabolic process	GO:1901657	246	0.023
purine containing compound catabolic process	GO:0072523	213	0.023
positive regulation of cellular amine metabolic process	GO:0033240	5	0.023
ribonucleotide catabolic process	GO:0009261	208	0.023
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.023
regulation of cytokine production	GO:0001817	266	0.023
synapse organization	GO:0050808	125	0.023
regulation of protein secretion	GO:0050708	82	0.023
cardiac muscle cell action potential involved in contraction	GO:0086002	6	0.022
embryonic epithelial tube formation	GO:0001838	130	0.022
epidermis development	GO:0008544	187	0.022
negative regulation of cytokine production	GO:0001818	84	0.022
single fertilization	GO:0007338	82	0.022
regulation of epidermal cell differentiation	GO:0045604	21	0.022
regulation of leukocyte differentiation	GO:1902105	159	0.022
regulation of cellular ketone metabolic process	GO:0010565	66	0.022
regulation of transmembrane transport	GO:0034762	128	0.022
cellular macromolecule catabolic process	GO:0044265	206	0.022
neural tube development	GO:0021915	160	0.022
organ growth	GO:0035265	117	0.021
rho protein signal transduction	GO:0007266	32	0.021
purine nucleotide catabolic process	GO:0006195	211	0.021
regulation of transferase activity	GO:0051338	263	0.021
central nervous system neuron differentiation	GO:0021953	162	0.021
response to nutrient levels	GO:0031667	109	0.021	Mouse
potassium ion homeostasis	GO:0055075	4	0.021
response to light stimulus	GO:0009416	135	0.021
regulation of response to drug	GO:2001023	2	0.021
response to organic cyclic compound	GO:0014070	198	0.021
regulation of tissue remodeling	GO:0034103	38	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.020
cellular response to molecule of bacterial origin	GO:0071219	83	0.020
cellular response to growth factor stimulus	GO:0071363	197	0.020
nucleoside triphosphate catabolic process	GO:0009143	205	0.020
response to organonitrogen compound	GO:0010243	246	0.020	Mouse
bone mineralization	GO:0030282	54	0.020
cardiac conduction	GO:0061337	17	0.020
protein catabolic process	GO:0030163	221	0.020
bone remodeling	GO:0046849	53	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.020
monocarboxylic acid metabolic process	GO:0032787	191	0.020
blastocyst formation	GO:0001825	33	0.020	Mouse
cardiac atrium development	GO:0003230	24	0.019
negative regulation of proteolysis	GO:0045861	74	0.019
binding of sperm to zona pellucida	GO:0007339	34	0.019
embryonic appendage morphogenesis	GO:0035113	126	0.019
carbohydrate derivative catabolic process	GO:1901136	231	0.019
inorganic cation transmembrane transport	GO:0098662	207	0.019
regulation of actin filament based movement	GO:1903115	12	0.019
regulation of neuron apoptotic process	GO:0043523	122	0.019
cellular response to biotic stimulus	GO:0071216	92	0.019
epithelial cell maturation	GO:0002070	15	0.019
regulation of epithelial cell proliferation	GO:0050678	141	0.019	Mouse
vasodilation	GO:0042311	28	0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.019
negative regulation of cellular amine metabolic process	GO:0033239	1	0.019
purine ribonucleoside metabolic process	GO:0046128	241	0.019
divalent inorganic cation homeostasis	GO:0072507	138	0.019
negative regulation of defense response	GO:0031348	77	0.018
posttranscriptional regulation of gene expression	GO:0010608	155	0.018
ribonucleoside metabolic process	GO:0009119	245	0.018
innate immune response	GO:0045087	157	0.018
regulation of leukocyte proliferation	GO:0070663	121	0.018
epithelial to mesenchymal transition	GO:0001837	47	0.018
cell cell junction organization	GO:0045216	72	0.018	Zebrafish Mouse
negative regulation of protein maturation	GO:1903318	79	0.018
sa node cell to atrial cardiac muscle cell communication	GO:0086070	5	0.018
nucleoside triphosphate metabolic process	GO:0009141	230	0.018
positive regulation of inflammatory response	GO:0050729	47	0.018
ventricular septum morphogenesis	GO:0060412	27	0.018
regulation of systemic arterial blood pressure mediated by a chemical signal	GO:0003044	33	0.017
nucleoside metabolic process	GO:0009116	246	0.017
nucleobase containing small molecule metabolic process	GO:0055086	352	0.017
regulation of ion transport	GO:0043269	215	0.017
regulation of lymphocyte proliferation	GO:0050670	117	0.017
t cell apoptotic process	GO:0070231	39	0.017
regulation of atrial cardiac muscle cell membrane depolarization	GO:0060371	5	0.017
regulation of neurotransmitter levels	GO:0001505	87	0.017
visual perception	GO:0007601	52	0.017
regulation of heart contraction	GO:0008016	77	0.017
endocytosis	GO:0006897	168	0.017
leukocyte mediated cytotoxicity	GO:0001909	62	0.017
apoptotic signaling pathway	GO:0097190	306	0.017
regulation of epidermis development	GO:0045682	33	0.017
hair cycle	GO:0042633	90	0.017
glutamate receptor signaling pathway	GO:0007215	35	0.017
negative regulation of peptidase activity	GO:0010466	46	0.017
stress activated mapk cascade	GO:0051403	80	0.017
calcium ion transport	GO:0006816	159	0.017
neuron death	GO:0070997	154	0.016
regulation of leukocyte apoptotic process	GO:2000106	56	0.016
cardiac chamber morphogenesis	GO:0003206	93	0.016
phospholipid metabolic process	GO:0006644	87	0.016
adult behavior	GO:0030534	135	0.016
multicellular organism growth	GO:0035264	161	0.016
positive regulation of transferase activity	GO:0051347	167	0.016
negative regulation of hydrolase activity	GO:0051346	71	0.016
striated muscle tissue development	GO:0014706	293	0.016
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.016
positive regulation of mapk cascade	GO:0043410	170	0.016	Mouse
cell communication involved in cardiac conduction	GO:0086065	9	0.016
macromolecule catabolic process	GO:0009057	281	0.016
chemotaxis	GO:0006935	247	0.016	Mouse
t cell activation	GO:0042110	289	0.016
regulation of lymphocyte activation	GO:0051249	240	0.016
regulation of cellular catabolic process	GO:0031329	242	0.016
inflammatory response to antigenic stimulus	GO:0002437	30	0.016
regulation of cellular component biogenesis	GO:0044087	181	0.015
myelination	GO:0042552	74	0.015
monocarboxylic acid biosynthetic process	GO:0072330	61	0.015
cellular metal ion homeostasis	GO:0006875	151	0.015
stress activated protein kinase signaling cascade	GO:0031098	81	0.015
fatty acid biosynthetic process	GO:0006633	41	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
biomineral tissue development	GO:0031214	64	0.015
feeding behavior	GO:0007631	62	0.015
cellular response to antibiotic	GO:0071236	4	0.015
purine ribonucleoside catabolic process	GO:0046130	205	0.015
response to amino acid	GO:0043200	37	0.015	Mouse
sensory perception of mechanical stimulus	GO:0050954	107	0.014	Mouse
regulation of circadian sleep wake cycle	GO:0042749	3	0.014
response to drug	GO:0042493	75	0.014
regulation of heart rate by cardiac conduction	GO:0086091	6	0.014
positive regulation of leukocyte proliferation	GO:0070665	73	0.014
regulation of bone remodeling	GO:0046850	28	0.014
memory	GO:0007613	58	0.014
regulation of purine nucleotide metabolic process	GO:1900542	169	0.014
amide transport	GO:0042886	138	0.014	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.014
negative regulation of phosphorus metabolic process	GO:0010563	184	0.014
regulation of receptor activity	GO:0010469	41	0.014
positive regulation of apoptotic process	GO:0043065	217	0.014
regulation of anatomical structure size	GO:0090066	178	0.014	Mouse
blastocyst development	GO:0001824	80	0.014	Mouse
jnk cascade	GO:0007254	72	0.014
carbohydrate derivative biosynthetic process	GO:1901137	183	0.014
exocytosis	GO:0006887	121	0.014
leukocyte apoptotic process	GO:0071887	71	0.014
morphogenesis of embryonic epithelium	GO:0016331	159	0.014
negative regulation of immune system process	GO:0002683	209	0.014
regulation of homeostatic process	GO:0032844	182	0.014
cytokine production	GO:0001816	319	0.014
myeloid cell differentiation	GO:0030099	233	0.014
cellular response to lipid	GO:0071396	145	0.013
regulation of cell cycle	GO:0051726	281	0.013
membrane repolarization	GO:0086009	7	0.013
negative regulation of response to wounding	GO:1903035	77	0.013
cellular response to peptide hormone stimulus	GO:0071375	92	0.013
lymphocyte differentiation	GO:0030098	242	0.013
activation of immune response	GO:0002253	138	0.013
wound healing	GO:0042060	157	0.013
glial cell differentiation	GO:0010001	131	0.013	Mouse
response to steroid hormone	GO:0048545	56	0.013
cardiac ventricle development	GO:0003231	83	0.013
metal ion homeostasis	GO:0055065	189	0.013
neuronal action potential	GO:0019228	54	0.013
multicellular organismal response to stress	GO:0033555	62	0.013
b cell activation	GO:0042113	161	0.013
regulation of saliva secretion	GO:0046877	2	0.013
spermatogenesis	GO:0007283	284	0.013
positive regulation of protein phosphorylation	GO:0001934	242	0.013
cardiac muscle cell action potential	GO:0086001	11	0.013
cellular chemical homeostasis	GO:0055082	215	0.013
action potential	GO:0001508	78	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.013
protein localization to organelle	GO:0033365	185	0.012
regulation of protein maturation	GO:1903317	96	0.012
hormone metabolic process	GO:0042445	86	0.012
tumor necrosis factor superfamily cytokine production	GO:0071706	51	0.012
learning or memory	GO:0007611	148	0.012
regulation of antimicrobial humoral response	GO:0002759	3	0.012
cell activation involved in immune response	GO:0002263	126	0.012
protein ubiquitination	GO:0016567	171	0.012
ventricular septum development	GO:0003281	42	0.012
nucleoside catabolic process	GO:0009164	206	0.012
cell division	GO:0051301	120	0.012
membrane depolarization during action potential	GO:0086010	5	0.012
synapse assembly	GO:0007416	56	0.012
positive regulation of protein modification process	GO:0031401	299	0.012
reactive oxygen species biosynthetic process	GO:1903409	8	0.012
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.012	Mouse
cardiac chamber development	GO:0003205	108	0.012
carbohydrate metabolic process	GO:0005975	230	0.012
regulation of apoptotic signaling pathway	GO:2001233	197	0.012
cell killing	GO:0001906	67	0.012
cation homeostasis	GO:0055080	212	0.012
positive regulation of ossification	GO:0045778	47	0.012
regulation of ventricular cardiac muscle cell membrane repolarization	GO:0060307	5	0.012
negative regulation of interleukin 6 production	GO:0032715	17	0.012
bmp signaling pathway	GO:0030509	93	0.012
forebrain development	GO:0030900	302	0.012
nerve development	GO:0021675	67	0.012
anatomical structure homeostasis	GO:0060249	145	0.012
regulation of cardiac muscle contraction	GO:0055117	21	0.012
sperm egg recognition	GO:0035036	37	0.011
renal system development	GO:0072001	225	0.011
positive regulation of response to wounding	GO:1903036	66	0.011
renal system process	GO:0003014	48	0.011
heart morphogenesis	GO:0003007	178	0.011
morphogenesis of a branching epithelium	GO:0061138	193	0.011	Mouse
cellular glucose homeostasis	GO:0001678	52	0.011
muscle cell differentiation	GO:0042692	261	0.011	Mouse
positive regulation of cell growth	GO:0030307	33	0.011	Mouse
interleukin 1 production	GO:0032612	31	0.011
t cell proliferation	GO:0042098	120	0.011
cellular component assembly involved in morphogenesis	GO:0010927	139	0.011
positive regulation of stress activated mapk cascade	GO:0032874	48	0.011
response to calcium ion	GO:0051592	20	0.011
skin morphogenesis	GO:0043589	38	0.011
positive regulation of antimicrobial humoral response	GO:0002760	2	0.011
positive regulation of cell death	GO:0010942	224	0.011
regulation of t cell activation	GO:0050863	170	0.011
glucose homeostasis	GO:0042593	128	0.011
regulation of nucleotide catabolic process	GO:0030811	122	0.011
organic acid biosynthetic process	GO:0016053	86	0.011
cytokine metabolic process	GO:0042107	71	0.011
ribose phosphate biosynthetic process	GO:0046390	59	0.011
regulation of systemic arterial blood pressure by hormone	GO:0001990	25	0.011
positive regulation of immune effector process	GO:0002699	107	0.011
establishment of skin barrier	GO:0061436	14	0.011
detection of stimulus involved in sensory perception	GO:0050906	44	0.011
negative regulation of t cell apoptotic process	GO:0070233	18	0.011
acute inflammatory response	GO:0002526	41	0.011
negative regulation of protein processing	GO:0010955	79	0.011
hair follicle morphogenesis	GO:0031069	29	0.011
cardiac septum morphogenesis	GO:0060411	46	0.011
steroid metabolic process	GO:0008202	119	0.011
organic acid transport	GO:0015849	101	0.011
digestive tract morphogenesis	GO:0048546	147	0.011	Zebrafish
glycerolipid metabolic process	GO:0046486	122	0.011
positive regulation of camp mediated signaling	GO:0043950	3	0.011
negative regulation of cell proliferation	GO:0008285	296	0.010	Mouse
regulation of cellular response to stress	GO:0080135	159	0.010
negative regulation of epithelial cell proliferation	GO:0050680	64	0.010	Mouse
negative regulation of lymphocyte apoptotic process	GO:0070229	24	0.010
cellular response to tumor necrosis factor	GO:0071356	21	0.010
regulation of protein catabolic process	GO:0042176	108	0.010
fertilization	GO:0009566	127	0.010
spongiotrophoblast layer development	GO:0060712	15	0.010
single organism cell adhesion	GO:0098602	156	0.010	Mouse
paramesonephric duct development	GO:0061205	3	0.010
positive regulation of jnk cascade	GO:0046330	46	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.010
negative regulation of protein modification process	GO:0031400	163	0.010
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure	GO:0001999	6	0.010
receptor mediated endocytosis	GO:0006898	51	0.010
regulation of multi organism process	GO:0043900	111	0.010
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.010
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.010
sperm motility	GO:0030317	47	0.010
lateral line system development	GO:0048925	1	0.010
unsaturated fatty acid biosynthetic process	GO:0006636	15	0.010
positive regulation of lymphocyte activation	GO:0051251	140	0.010
long term synaptic potentiation	GO:0060291	25	0.010
protein modification by small protein conjugation	GO:0032446	187	0.010

Dsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.017
central nervous system disease	DOID:331	0.017
nervous system disease	DOID:863	0.017
neurodegenerative disease	DOID:1289	0.017

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