Mus musculus

115 known processes

Hsf1

heat shock factor 1

(Aliases: AA960185)

Hsf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein catabolic processGO:00442571550.481
proteolysis involved in cellular protein catabolic processGO:00516031470.432
proteasomal protein catabolic processGO:0010498980.408
modification dependent protein catabolic processGO:00199411330.394
modification dependent macromolecule catabolic processGO:00436321330.372
protein ubiquitinationGO:00165671710.334
protein modification by small protein conjugation or removalGO:00706472070.266
ubiquitin dependent protein catabolic processGO:00065111290.235
protein catabolic processGO:00301632210.222
regulation of cellular catabolic processGO:00313292420.204
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.173
positive regulation of cellular catabolic processGO:00313311480.171
chromatin modificationGO:00165681870.168
Mouse
macromolecule catabolic processGO:00090572810.150
leukocyte differentiationGO:00025213420.140
defense response to bacteriumGO:00427421190.126
Worm Fly
positive regulation of programmed cell deathGO:00430682180.121
cellular macromolecule catabolic processGO:00442652060.121
regulation of protein kinase activityGO:00458592320.116
cellular ketone metabolic processGO:0042180840.111
negative regulation of protein metabolic processGO:00512482820.110
protein import into nucleusGO:0006606950.101
regulation of antimicrobial humoral responseGO:000275930.100
regulation of hydrolase activityGO:00513362460.095
multi multicellular organism processGO:00447061090.092
protein targetingGO:00066051430.089
dna metabolic processGO:00062593030.087
regulation of protein serine threonine kinase activityGO:00719001570.085
regulation of cellular ketone metabolic processGO:0010565660.085
establishment of protein localization to organelleGO:00725941180.084
protein localization to nucleusGO:00345041210.078
positive regulation of purine nucleotide metabolic processGO:19005441140.078
antimicrobial peptide productionGO:000277520.077
lymphocyte differentiationGO:00300982420.076
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.068
covalent chromatin modificationGO:00165691630.068
Mouse
ribonucleotide metabolic processGO:00092592910.067
regulation of protein catabolic processGO:00421761080.067
regulation of mrna metabolic processGO:1903311430.066
regulation of multi organism processGO:00439001110.065
regulation of cellular protein catabolic processGO:1903362610.065
carbohydrate derivative catabolic processGO:19011362310.063
negative regulation of molecular functionGO:00440922580.061
homeostasis of number of cellsGO:00488722100.061
purine nucleoside catabolic processGO:00061522050.057
rhythmic processGO:00485111740.056
ribose phosphate metabolic processGO:00196932910.055
glycosyl compound metabolic processGO:19016572460.054
developmental growth involved in morphogenesisGO:00605601380.054
negative regulation of cellular protein metabolic processGO:00322692470.054
histone methylationGO:0016571710.053
positive regulation of hydrolase activityGO:00513451480.053
regulation of protein import into nucleusGO:0042306520.053
regulation of intracellular transportGO:00323861590.053
regulation of cytoplasmic transportGO:19036491120.053
organonitrogen compound biosynthetic processGO:19015661920.052
immune effector processGO:00022523210.051
peptidyl amino acid modificationGO:00181933360.050
purine nucleoside triphosphate metabolic processGO:00091442260.050
regulation of antimicrobial peptide productionGO:000278410.049
establishment of monopolar cell polarityGO:006116280.049
small gtpase mediated signal transductionGO:0007264970.049
regulation of proteasomal protein catabolic processGO:0061136460.048
regulation of myeloid cell differentiationGO:0045637960.047
regulation of reactive oxygen species biosynthetic processGO:190342620.047
purine nucleoside triphosphate catabolic processGO:00091462030.047
nucleocytoplasmic transportGO:00069131390.047
protein importGO:00170381010.047
positive regulation of gtp catabolic processGO:0033126850.046
regulation of homeostatic processGO:00328441820.046
protein alkylationGO:0008213810.046
histone deubiquitinationGO:001657820.046
positive regulation of protein phosphorylationGO:00019342420.045
reactive oxygen species biosynthetic processGO:190340980.045
mammary gland epithelium developmentGO:0061180650.045
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.045
spermatogenesisGO:00072832840.044
ribonucleoside triphosphate metabolic processGO:00091992200.044
glycosyl compound catabolic processGO:19016582060.044
positive regulation of kinase activityGO:00336741550.044
gland developmentGO:00487323300.043
digestive system developmentGO:00551232000.043
positive regulation of protein modification processGO:00314012990.043
purine ribonucleotide metabolic processGO:00091502900.043
organic cyclic compound catabolic processGO:19013612950.042
nucleobase containing small molecule metabolic processGO:00550863520.042
nucleotide catabolic processGO:00091662170.042
cytokine biosynthetic processGO:0042089680.042
regulation of protein targetingGO:1903533610.041
regulation of organelle organizationGO:00330432890.041
epithelial tube formationGO:00721751300.041
nuclear transportGO:00511691390.041
skeletal system developmentGO:00015013560.041
intracellular receptor signaling pathwayGO:0030522740.040
negative regulation of protein phosphorylationGO:00019331260.039
ras protein signal transductionGO:0007265770.038
purine nucleoside metabolic processGO:00422782410.038
regulation of proteolysisGO:00301621640.038
ribonucleoside triphosphate catabolic processGO:00092031990.038
defense response to other organismGO:00985421970.038
Worm Fly
negative regulation of kinase activityGO:0033673810.037
sequestering of calcium ionGO:0051208180.036
regulation of protein bindingGO:0043393600.036
nucleoside metabolic processGO:00091162460.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
chromatin organizationGO:00063252060.035
Mouse
negative regulation of cell proliferationGO:00082852960.034
regulation of bindingGO:00510981110.034
Fly
regulation of defense response to bacteriumGO:190042430.034
cellular amine metabolic processGO:0044106440.033
regulation of transferase activityGO:00513382630.033
ribonucleotide catabolic processGO:00092612080.033
cellular amino acid metabolic processGO:00065201030.033
nucleoside triphosphate metabolic processGO:00091412300.033
skeletal system morphogenesisGO:00487052030.033
dna replicationGO:0006260520.033
regulation of defense responseGO:00313472330.033
actin cytoskeleton organizationGO:00300362200.033
response to painGO:0048265260.032
response to organic cyclic compoundGO:00140701980.032
Fly
ribonucleoside catabolic processGO:00424542060.032
nucleoside catabolic processGO:00091642060.032
protein modification by small protein conjugationGO:00324461870.032
primary neural tube formationGO:0014020950.031
regulation of kinase activityGO:00435492490.031
negative regulation of immune system processGO:00026832090.031
negative regulation of multi organism processGO:0043901680.031
macromolecule methylationGO:00434141200.031
cellular response to lipidGO:00713961450.031
purine nucleotide metabolic processGO:00061633020.030
intracellular protein transportGO:00068862040.029
response to organonitrogen compoundGO:00102432460.029
Fly
neurotransmitter secretionGO:0007269620.028
nuclear importGO:0051170950.028
response to decreased oxygen levelsGO:0036293590.028
regulation of cellular amino acid metabolic processGO:000652150.028
positive regulation of nucleoside metabolic processGO:0045979910.028
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
single organism nuclear importGO:1902593950.028
positive regulation of cellular protein catabolic processGO:1903364340.028
intracellular mrna localizationGO:000829840.028
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.028
positive regulation of cell deathGO:00109422240.028
regulation of cytoskeleton organizationGO:00514931220.027
posttranscriptional regulation of gene expressionGO:00106081550.027
rna processingGO:00063961050.027
regulation of chromosome organizationGO:0033044830.026
forebrain developmentGO:00309003020.026
regulation of protein localizationGO:00328802310.026
positive regulation of proteolysisGO:0045862850.026
negative regulation of protein modification processGO:00314001630.026
negative regulation of transferase activityGO:0051348850.026
regulation of purine nucleotide metabolic processGO:19005421690.026
myeloid cell homeostasisGO:00022621140.026
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.026
positive regulation of protein catabolic processGO:0045732600.026
adaptive immune responseGO:00022501550.025
response to radiationGO:00093141650.025
regulation of ras gtpase activityGO:0032318880.025
positive regulation of nucleotide metabolic processGO:00459811140.025
positive regulation of organelle organizationGO:00106381280.025
methylationGO:00322591340.025
positive regulation of neuron differentiationGO:00456661410.025
t cell differentiationGO:00302171740.025
positive regulation of protein serine threonine kinase activityGO:00719021060.025
nucleoside phosphate metabolic processGO:00067533380.024
telencephalon developmentGO:00215371860.024
innate immune responseGO:00450871570.024
Worm
negative regulation of growthGO:0045926990.024
positive regulation of nucleotide catabolic processGO:0030813880.024
urogenital system developmentGO:00016552610.024
establishment of organelle localizationGO:00516561220.024
stem cell developmentGO:00488642190.024
organonitrogen compound catabolic processGO:19015652640.024
regulation of mapk cascadeGO:00434082480.024
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.024
stem cell maintenanceGO:00198271300.024
regulation of establishment of protein localizationGO:00702011810.024
positive regulation of apoptotic processGO:00430652170.024
fat cell differentiationGO:00454441600.023
cation homeostasisGO:00550802120.023
guanosine containing compound catabolic processGO:19010691440.023
regulation of transcription factor import into nucleusGO:0042990240.023
positive regulation of gtpase activityGO:0043547850.023
mrna metabolic processGO:0016071840.023
regulation of apoptotic signaling pathwayGO:20012331970.023
connective tissue developmentGO:00614481790.023
neurotransmitter transportGO:0006836760.023
lipid homeostasisGO:0055088630.023
tube closureGO:0060606910.023
sensory organ morphogenesisGO:00905962420.023
nucleoside phosphate catabolic processGO:19012922220.022
carbohydrate metabolic processGO:00059752300.022
regionalizationGO:00030023370.022
sensory perceptionGO:00076002450.022
regulation of nucleotide metabolic processGO:00061401690.022
protein methylationGO:0006479810.022
organophosphate catabolic processGO:00464342320.022
response to temperature stimulusGO:0009266550.022
positive regulation of protein kinase activityGO:00458601440.022
cytokine metabolic processGO:0042107710.022
negative regulation of intracellular signal transductionGO:19025321670.021
Yeast
myeloid leukocyte differentiationGO:00025731190.021
regulation of mrna processingGO:0050684410.021
rna splicingGO:0008380540.021
regulation of purine nucleotide catabolic processGO:00331211220.021
regulation of wnt signaling pathwayGO:00301111230.021
response to oxidative stressGO:00069791230.021
cellular response to peptide hormone stimulusGO:0071375920.020
protein localization to organelleGO:00333651850.020
regulation of anatomical structure sizeGO:00900661780.020
response to molecule of bacterial originGO:00022371430.020
regulation of neuron projection developmentGO:00109751690.020
activation of rac gtpase activityGO:003286320.020
leukocyte activation involved in immune responseGO:00023661260.020
cell growthGO:00160491300.020
negative regulation of cellular response to insulin stimulusGO:1900077160.020
production of molecular mediator of immune responseGO:00024401030.020
positive regulation of apoptotic signaling pathwayGO:2001235950.020
organ growthGO:00352651170.019
muscle tissue developmentGO:00605373080.019
circadian rhythmGO:00076231140.019
amine metabolic processGO:0009308450.019
cell activation involved in immune responseGO:00022631260.019
purine containing compound catabolic processGO:00725232130.019
regulation of nucleocytoplasmic transportGO:0046822730.019
regulation of neuron deathGO:19012141340.019
purine ribonucleoside catabolic processGO:00461302050.019
apoptotic signaling pathwayGO:00971903060.019
i kappab kinase nf kappab signalingGO:0007249850.019
spermatid differentiationGO:00485151150.019
wnt signaling pathwayGO:00160551880.018
regulation of intracellular protein transportGO:0033157820.018
embryonic organ morphogenesisGO:00485622760.018
regulation of cellular component biogenesisGO:00440871810.018
myeloid cell differentiationGO:00300992330.018
regulation of leukocyte differentiationGO:19021051590.018
heterocycle catabolic processGO:00467002800.018
cellular homeostasisGO:00197252400.018
establishment of planar polarityGO:0001736280.018
positive regulation of cell projection organizationGO:0031346950.017
nucleotide metabolic processGO:00091173320.017
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.017
purine ribonucleotide catabolic processGO:00091542080.017
somitogenesisGO:0001756690.017
regulation of actin filament based processGO:0032970990.017
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoterGO:007236470.017
hexose metabolic processGO:0019318980.017
regulation of production of molecular mediator of immune responseGO:0002700650.017
positive regulation of transferase activityGO:00513471670.017
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.017
lymphocyte mediated immunityGO:00024491390.017
skeletal muscle organ developmentGO:00605381630.017
ribonucleoside metabolic processGO:00091192450.016
regulation of cell cycle processGO:00105641600.016
response to reactive oxygen speciesGO:0000302560.016
negative regulation of immune effector processGO:0002698550.016
tissue homeostasisGO:00018941150.016
execution phase of apoptosisGO:0097194190.016
embryonic epithelial tube formationGO:00018381300.016
stem cell differentiationGO:00488632680.016
negative regulation of protein maturationGO:1903318790.016
action potentialGO:0001508780.016
wound healingGO:00420601570.016
positive regulation of neuron projection developmentGO:0010976790.016
cellular nitrogen compound catabolic processGO:00442702800.016
negative regulation of phosphorylationGO:00423261660.016
epidermis developmentGO:00085441870.016
regulation of fat cell differentiationGO:0045598810.016
cytokine productionGO:00018163190.016
metal ion homeostasisGO:00550651890.016
response to oxygen levelsGO:0070482620.016
positive regulation of purine nucleotide catabolic processGO:0033123880.016
neural tube developmentGO:00219151600.016
regulation of cellular amine metabolic processGO:0033238200.016
cellular ion homeostasisGO:00068731650.015
guanosine containing compound metabolic processGO:19010681440.015
negative regulation of defense responseGO:0031348770.015
regulation of response to biotic stimulusGO:0002831380.015
pharynx developmentGO:006046510.015
cellular response to oxidative stressGO:0034599760.015
positive regulation of protein transportGO:0051222930.015
response to peptideGO:19016521360.015
response to retinoic acidGO:0032526560.015
aromatic compound catabolic processGO:00194392860.015
cellular response to organic cyclic compoundGO:0071407870.015
dna methylationGO:0006306430.015
regulation of protein transportGO:00512231630.015
renal system developmentGO:00720012250.015
regulation of cytokine biosynthetic processGO:0042035590.015
synaptic transmissionGO:00072683290.015
microtubule based processGO:00070172360.015
Yeast
protein import into nucleus translocationGO:0000060120.015
regulation of cell growthGO:0001558910.015
glucose metabolic processGO:0006006920.015
ossificationGO:00015032160.014
rna interferenceGO:001624620.014
positive regulation of ras gtpase activityGO:0032320650.014
lymphocyte activation involved in immune responseGO:0002285930.014
positive regulation of cellular amine metabolic processGO:003324050.014
nucleoside monophosphate catabolic processGO:0009125590.014
regulation of muscle tissue developmentGO:1901861970.014
positive regulation of nervous system developmentGO:00519622210.014
positive regulation of cell developmentGO:00107202370.014
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.014
multicellular organismal response to stressGO:0033555620.014
immune response regulating signaling pathwayGO:00027641250.014
regulation of nucleotide catabolic processGO:00308111220.014
gonad developmentGO:00084061410.014
Worm
cellular response to growth factor stimulusGO:00713631970.014
hexose biosynthetic processGO:0019319390.014
establishment or maintenance of monopolar cell polarityGO:006133980.014
habituationGO:004695930.014
mrna processingGO:0006397630.014
regulation of ras protein signal transductionGO:00465781140.014
cellular response to cytokine stimulusGO:00713451890.014
localization within membraneGO:005166840.014
positive regulation of cytosolic calcium ion concentrationGO:0007204650.013
multicellular organismal homeostasisGO:00488711640.013
positive regulation of cellular component biogenesisGO:0044089940.013
neuron deathGO:00709971540.013
kidney developmentGO:00018222130.013
transmission of nerve impulseGO:0019226760.013
purine nucleotide catabolic processGO:00061952110.013
spermatid developmentGO:00072861080.013
transcription factor import into nucleusGO:0042991260.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
tube formationGO:00351481400.013
mammary gland epithelial cell proliferationGO:0033598240.013
intermediate filament cytoskeleton organizationGO:0045104260.013
glucose homeostasisGO:00425931280.013
positive regulation of defense responseGO:00313491240.013
positive regulation of cytokine biosynthetic processGO:0042108400.013
regulation of cell morphogenesis involved in differentiationGO:00107691510.013
multi organism reproductive behaviorGO:0044705290.013
regulation of nucleoside metabolic processGO:00091181300.013
regulation of lymphocyte differentiationGO:00456191070.013
negative regulation of dna replicationGO:000815640.013
cellular response to peptideGO:1901653920.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
digestive tract developmentGO:00485651900.013
regulation of cellular component sizeGO:00325351210.012
carbohydrate biosynthetic processGO:0016051740.012
positive regulation of homeostatic processGO:0032846640.012
regulation of transcription from rna polymerase iii promoterGO:000635920.012
nucleoside triphosphate catabolic processGO:00091432050.012
regulation of myeloid leukocyte differentiationGO:0002761580.012
cellular response to organonitrogen compoundGO:00714171450.012
reactive nitrogen species metabolic processGO:200105700.012
positive regulation of mapk cascadeGO:00434101700.012
purine ribonucleoside metabolic processGO:00461282410.012
histone modificationGO:00165701590.012
Mouse
cation transportGO:00068123990.012
cellular protein complex assemblyGO:00436231160.012
calcium ion homeostasisGO:00550741270.012
positive regulation of wnt signaling pathwayGO:0030177450.012
multicellular organismal reproductive behaviorGO:0033057230.012
cellular response to hormone stimulusGO:00328701500.012
male gamete generationGO:00482322850.012
leukocyte homeostasisGO:0001776790.012
positive regulation of dna templated transcription elongationGO:003278620.012
maintenance of locationGO:0051235890.012
dna templated transcription elongationGO:0006354130.012
germ cell developmentGO:00072811850.012
divalent inorganic cation transportGO:00725111780.012
negative regulation of proteolysisGO:0045861740.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
dna conformation changeGO:0071103370.012
regulation of striated muscle cell differentiationGO:0051153810.012
cell divisionGO:00513011200.012
sensory perception of mechanical stimulusGO:00509541070.012
purine containing compound metabolic processGO:00725213110.012
somite developmentGO:0061053810.012
locomotory behaviorGO:00076261950.012
intracellular steroid hormone receptor signaling pathwayGO:0030518290.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
camera type eye developmentGO:00430102660.012
Zebrafish Mouse
exocytosisGO:00068871210.012
chemotaxisGO:00069352470.012
fertilizationGO:00095661270.011
neural tube formationGO:00018411080.011
endochondral bone morphogenesisGO:0060350500.011
regulation of antimicrobial peptide biosynthetic processGO:000280510.011
reactive oxygen species metabolic processGO:0072593840.011
response to light stimulusGO:00094161350.011
regulation of canonical wnt signaling pathwayGO:0060828820.011
anatomical structure homeostasisGO:00602491450.011
carbohydrate homeostasisGO:00335001280.011
development of primary sexual characteristicsGO:00451371430.011
Worm
cellular response to acid chemicalGO:0071229680.011
ameboidal type cell migrationGO:00016671280.011
monosaccharide metabolic processGO:00059961060.011
establishment of synaptic vesicle localizationGO:0097480570.011
cytoplasmic transportGO:00164822340.011
muscle cell differentiationGO:00426922610.011
cell type specific apoptotic processGO:00972852680.011
peptidyl tyrosine modificationGO:00182121450.011
regulation of insulin receptor signaling pathwayGO:0046626210.011
peptidyl tyrosine phosphorylationGO:00181081430.011
regulation of ral protein signal transductionGO:003248540.011
cd4 positive alpha beta t cell differentiationGO:0043367410.011
striated muscle cell developmentGO:00550021250.011
epithelial cell proliferationGO:00506731740.011
regulation of neurotransmitter levelsGO:0001505870.011
regulation of translational initiationGO:0006446150.011
regulation of protein maturationGO:1903317960.011
blastocyst developmentGO:0001824800.011
mitochondrion organizationGO:00070051340.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
regulation of endopeptidase activityGO:0052548890.011
atp metabolic processGO:0046034750.011
respiratory tube developmentGO:00303231670.011
multicellular organismal signalingGO:0035637910.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
viral gene expressionGO:001908030.010
canonical wnt signaling pathwayGO:00600701300.010
mitochondrion transport along microtubuleGO:004749730.010
b cell activation involved in immune responseGO:0002312500.010
regulation of neuron differentiationGO:00456642810.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
protein autophosphorylationGO:0046777610.010
regulation of actin cytoskeleton organizationGO:0032956840.010
negative regulation of nervous system developmentGO:00519611560.010
regulation of metal ion transportGO:00109591060.010
retrograde transport endosome to golgiGO:004214720.010
regulation of calcium ion transportGO:0051924690.010
multi organism behaviorGO:0051705620.010
ensheathment of neuronsGO:0007272760.010
pole plasm assemblyGO:000731520.010
regulation of cell activationGO:00508652890.010
positive regulation of myeloid cell differentiationGO:0045639430.010
peptidyl arginine omega n methylationGO:003524720.010
sequestering of metal ionGO:0051238190.010
myotube differentiationGO:00149021050.010
prostate gland developmentGO:0030850480.010

Hsf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.015
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.014