IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Rexo4

REX4, RNA exonuclease 4 homolog (S. cerevisiae)

(Aliases: Gm111,Xpmc2h)

Entrez: 227656
Ensembl: ENSMUSG00000052406
UniProtKB: Q6PAQ4

Process Predictions
Disease Predictions

Rexo4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
muscle tissue development	GO:0060537	308	0.036
rna processing	GO:0006396	105	0.036
regulation of cellular ketone metabolic process	GO:0010565	66	0.035
regulation of cell cycle	GO:0051726	281	0.034
cellular ketone metabolic process	GO:0042180	84	0.033
chromatin modification	GO:0016568	187	0.031
regulation of cellular amino acid metabolic process	GO:0006521	5	0.030
macromolecule methylation	GO:0043414	120	0.030
regulation of cellular amine metabolic process	GO:0033238	20	0.029
leukocyte mediated immunity	GO:0002443	174	0.029
cellular amine metabolic process	GO:0044106	44	0.029
amine metabolic process	GO:0009308	45	0.027
regulation of lymphocyte activation	GO:0051249	240	0.026
covalent chromatin modification	GO:0016569	163	0.025
purine containing compound metabolic process	GO:0072521	311	0.024
regulation of cell activation	GO:0050865	289	0.024
chromatin organization	GO:0006325	206	0.023
positive regulation of cell death	GO:0010942	224	0.023
nucleoside metabolic process	GO:0009116	246	0.023
maturation of 5 8s rrna	GO:0000460	1	0.023
striated muscle tissue development	GO:0014706	293	0.023
organelle fission	GO:0048285	170	0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.022
peptidyl amino acid modification	GO:0018193	336	0.022
cellular amino acid metabolic process	GO:0006520	103	0.022
immune effector process	GO:0002252	321	0.022
nuclear division	GO:0000280	158	0.021
purine nucleotide metabolic process	GO:0006163	302	0.021
positive regulation of apoptotic process	GO:0043065	217	0.020
ribonucleotide metabolic process	GO:0009259	291	0.020
cell type specific apoptotic process	GO:0097285	268	0.019
positive regulation of programmed cell death	GO:0043068	218	0.019
histone modification	GO:0016570	159	0.019
lymphocyte mediated immunity	GO:0002449	139	0.019
cytoplasmic transport	GO:0016482	234	0.018
ncrna 3 end processing	GO:0043628	2	0.018
t cell activation	GO:0042110	289	0.018
dna metabolic process	GO:0006259	303	0.018
cell activation involved in immune response	GO:0002263	126	0.018
cellular nitrogen compound catabolic process	GO:0044270	280	0.018
neuron death	GO:0070997	154	0.018
negative regulation of immune system process	GO:0002683	209	0.017
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.017
cytokine production	GO:0001816	319	0.017
myeloid cell differentiation	GO:0030099	233	0.017
microtubule based process	GO:0007017	236	0.017
regulation of organelle organization	GO:0033043	289	0.017
camera type eye development	GO:0043010	266	0.017
glycosyl compound metabolic process	GO:1901657	246	0.017
endocytosis	GO:0006897	168	0.017
skeletal muscle organ development	GO:0060538	163	0.016
regulation of anatomical structure size	GO:0090066	178	0.016
positive regulation of cellular amine metabolic process	GO:0033240	5	0.016
mitotic cell cycle	GO:0000278	195	0.016
methylation	GO:0032259	134	0.016
nitrogen compound transport	GO:0071705	271	0.016
epithelial tube morphogenesis	GO:0060562	303	0.016
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.016
regulation of t cell activation	GO:0050863	170	0.016
nucleoside phosphate metabolic process	GO:0006753	338	0.016
nucleotide catabolic process	GO:0009166	217	0.016
nuclear transport	GO:0051169	139	0.016
carbohydrate derivative catabolic process	GO:1901136	231	0.015
negative regulation of cell proliferation	GO:0008285	296	0.015
regulation of t cell differentiation	GO:0045580	83	0.015
negative regulation of cellular protein metabolic process	GO:0032269	247	0.015
carbohydrate metabolic process	GO:0005975	230	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
multicellular organismal signaling	GO:0035637	91	0.015
organelle localization	GO:0051640	179	0.015
transcription from rna polymerase iii promoter	GO:0006383	3	0.014
neuron apoptotic process	GO:0051402	142	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.014
b cell activation	GO:0042113	161	0.014
carbohydrate derivative biosynthetic process	GO:1901137	183	0.014
leukocyte differentiation	GO:0002521	342	0.014
nucleoside phosphate catabolic process	GO:1901292	222	0.014
negative regulation of protein metabolic process	GO:0051248	282	0.014
stem cell differentiation	GO:0048863	268	0.014
aromatic compound catabolic process	GO:0019439	286	0.014
leukocyte activation involved in immune response	GO:0002366	126	0.014
cellular protein complex assembly	GO:0043623	116	0.014
purine ribonucleotide metabolic process	GO:0009150	290	0.013
ribonucleotide catabolic process	GO:0009261	208	0.013
cell division	GO:0051301	120	0.013
negative regulation of phosphate metabolic process	GO:0045936	184	0.013
spermatogenesis	GO:0007283	284	0.013
response to radiation	GO:0009314	165	0.013
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.013
organonitrogen compound catabolic process	GO:1901565	264	0.013
response to organonitrogen compound	GO:0010243	246	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
multicellular organismal homeostasis	GO:0048871	164	0.012
heterocycle catabolic process	GO:0046700	280	0.012
male gamete generation	GO:0048232	285	0.012
somatic diversification of immunoglobulins	GO:0016445	43	0.012
mrna processing	GO:0006397	63	0.012
lymphocyte differentiation	GO:0030098	242	0.012
small gtpase mediated signal transduction	GO:0007264	97	0.012
dna repair	GO:0006281	107	0.012
transmission of nerve impulse	GO:0019226	76	0.012
purine ribonucleoside catabolic process	GO:0046130	205	0.012
purine nucleoside metabolic process	GO:0042278	241	0.012
hematopoietic progenitor cell differentiation	GO:0002244	143	0.012
actin cytoskeleton organization	GO:0030036	220	0.012
regulation of intracellular transport	GO:0032386	159	0.012
regulation of cytoplasmic transport	GO:1903649	112	0.012
regulation of membrane potential	GO:0042391	192	0.012
anatomical structure homeostasis	GO:0060249	145	0.012
negative regulation of molecular function	GO:0044092	258	0.012
macromolecule catabolic process	GO:0009057	281	0.012
lymphocyte activation involved in immune response	GO:0002285	93	0.012
muscle cell differentiation	GO:0042692	261	0.012
mapk cascade	GO:0000165	281	0.011
blood vessel morphogenesis	GO:0048514	285	0.011
regulation of leukocyte differentiation	GO:1902105	159	0.011
regulation of transferase activity	GO:0051338	263	0.011
protein localization to organelle	GO:0033365	185	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.011
regulation of lymphocyte differentiation	GO:0045619	107	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.011
cation transport	GO:0006812	399	0.011
lipoprotein metabolic process	GO:0042157	43	0.011
t cell differentiation	GO:0030217	174	0.011
mrna metabolic process	GO:0016071	84	0.011
production of molecular mediator of immune response	GO:0002440	103	0.011
regulation of neuron apoptotic process	GO:0043523	122	0.011
regulation of mrna metabolic process	GO:1903311	43	0.011
mitotic cell cycle process	GO:1903047	159	0.011
microtubule cytoskeleton organization	GO:0000226	157	0.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000466	1	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
regulation of neuron death	GO:1901214	134	0.011
ribonucleoside catabolic process	GO:0042454	206	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
maintenance of location	GO:0051235	89	0.010
protein localization to nucleus	GO:0034504	121	0.010
dephosphorylation	GO:0016311	129	0.010
adaptive immune response	GO:0002250	155	0.010
purine ribonucleoside metabolic process	GO:0046128	241	0.010
circadian rhythm	GO:0007623	114	0.010
negative regulation of intracellular signal transduction	GO:1902532	167	0.010
organic cyclic compound catabolic process	GO:1901361	295	0.010
regulation of cellular component biogenesis	GO:0044087	181	0.010
regulation of protein transport	GO:0051223	163	0.010
cell growth	GO:0016049	130	0.010
lateral inhibition	GO:0046331	1	0.010
negative regulation of protein modification process	GO:0031400	163	0.010
viral process	GO:0016032	41	0.010
nucleoside monophosphate metabolic process	GO:0009123	85	0.010
response to acid chemical	GO:0001101	111	0.010
organism emergence from protective structure	GO:0071684	4	0.010

Rexo4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.019
nervous system disease	DOID:863	0.019
cancer	DOID:162	0.011
disease of cellular proliferation	DOID:14566	0.011
organ system cancer	DOID:0050686	0.010

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